 Gene-Chemical Interaction Annotations | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene Ontology AnnotationsMolecular Pathway Annotations |
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Analyze GeneStrainQTL List |
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Gene Ontology AnnotationsMolecular Pathway AnnotationsDisease AnnotationsGene-Chemical Interaction Annotations
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Gene Ontology AnnotationsBiological Process
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Cellular Component
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Molecular Function
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Molecular Pathway Annotations
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References - curated| 1. | Antonin W, etal., Nat Struct Biol 2002 Feb;9(2):107-11. |
| 2. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
| 3. | GOA data from the GO Consortium |
| 4. | MGD data from the GO Consortium |
| 5. | NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
| 6. | Pipeline to import KEGG annotations from KEGG into RGD |
| 7. | Pryor PR, etal., EMBO Rep. 2004 Jun;5(6):590-5. Epub 2004 May 7. |
| 8. | RGD automated data pipeline |
| 9. | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 10. | RGD automated import pipeline for gene-chemical interactions |
| 11. | Richardson SC, etal., Mol Biol Cell 2004 Mar;15(3):1197-210. Epub 2003 Dec 10. |
| 12. | Takamori S, etal., Cell. 2006 Nov 17;127(4):831-46. |
| 13. | Wilhelm BG, etal., Science. 2014 May 30;344(6187):1023-8. doi: 10.1126/science.1252884. |
| 14. | Wong SH, etal., J Biol Chem 1998 Jan 2;273(1):375-80. |
References - uncurated| PubMed | 10564279 11101518 12477932 17897319 18321981 18570918 18980942 19549681 20170677 20458337 21438968 21700703 22871113 23376485 24550300 |
Genomics
Comparative Map Data| Stx7 (Rattus norvegicus - Norway rat) |
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| STX7 (Homo sapiens - human) |
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| Stx7 (Mus musculus - house mouse) |
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| Stx7 (Chinchilla lanigera - long-tailed chinchilla) |
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| STX7 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| STX7 (Canis lupus familiaris - dog) |
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| Stx7 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| STX7 (Sus scrofa - pig) |
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| STX7 (Chlorocebus sabaeus - African green monkey) |
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| Stx7 (Heterocephalus glaber - naked mole-rat) |
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Position Markers| BF403910 |
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QTLs in Region (Rnor_6.0)| The following QTLs overlap with this region. |  | Full Report | | CSV | | TAB | | Printer | | Gviewer |
miRNA Target Status
Predicted Target Of
| The detailed report is available here: | | Full Report | | CSV | | TAB | | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
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Expression
RNA-SEQ ExpressionHigh: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM
| alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
| High | |||||||||||||
| Medium | 3 | 41 | 52 | 36 | 19 | 36 | 1 | 1 | 74 | 35 | 34 | 11 | 1 |
| Low | 2 | 5 | 5 | 5 | 7 | 10 | 7 | 7 | |||||
| Below cutoff |
View RNA-SEQ Expression Data
Sequence
Nucleotide Sequences| RefSeq Transcripts | NM_021869 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| XM_017589644 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_017589645 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_017589646 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| GenBank Nucleotide | AABR07071852 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| AAHX01002024 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AAHX01002025 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AC116279 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| AF031430 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| BC085737 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| CH474002 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
Reference Sequences
| RefSeq Acc Id: | ENSRNOT00000021318 ⟹ ENSRNOP00000021318 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | ENSRNOT00000081804 ⟹ ENSRNOP00000073994 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | NM_021869 ⟹ NP_068641 | ||||||||||||||||||||
| RefSeq Status: | PROVISIONAL | ||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||
| Position: |
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| Sequence: |
GCAGCTGGAGGTGACAGAGGAAGCCAACGAGGTGACTCCTAGAAAACCCGACAGCCTGCTTGCAhide sequence |
| RefSeq Acc Id: | XM_017589644 ⟹ XP_017445133 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| Sequence: |
GTGCTTGCGCCACCGCCCATTCGCTGAGACTGGCTGCGCAGGGCCGTGGGCCCTCGGTGACAGChide sequence |
| RefSeq Acc Id: | XM_017589645 ⟹ XP_017445134 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| Sequence: |
ATATGCATATATTATTTTTGGTTGCTTTAGATCTCGTATTCTGTTAGGAATTATTATTTACAAGhide sequence |
| RefSeq Acc Id: | XM_017589646 ⟹ XP_017445135 | ||||||||
| RefSeq Status: | |||||||||
| Type: | CODING | ||||||||
| Position: |
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| Sequence: |
AACCACTGCTCGCCGGTGGTTGGTTTGGGGTGCGCAGAGCGGGGCTCCCTAGGGCGCAGGGCCAhide sequence |
Protein Sequences| Protein RefSeqs | NP_068641 | (Get FASTA) | NCBI Sequence Viewer |
| XP_017445133 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_017445134 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_017445135 | (Get FASTA) | NCBI Sequence Viewer | |
| GenBank Protein | AAC17131 | (Get FASTA) | NCBI Sequence Viewer |
| AAH85737 | (Get FASTA) | NCBI Sequence Viewer | |
| EDL87765 | (Get FASTA) | NCBI Sequence Viewer | |
| EDL87766 | (Get FASTA) | NCBI Sequence Viewer | |
| EDL87767 | (Get FASTA) | NCBI Sequence Viewer | |
| EDL87768 | (Get FASTA) | NCBI Sequence Viewer | |
| O70257 | (Get FASTA) | NCBI Sequence Viewer |
Reference Sequences
| RefSeq Acc Id: | NP_068641 ⟸ NM_021869 |
| - UniProtKB: | O70257 (UniProtKB/Swiss-Prot) |
| - Sequence: |
MSYTPGIGGDPAQLAQRISSNIQKITQCSAEIQRTLNQLGTPQDTPELRQQLQQEQQYTNQLAKhide sequence |
| RefSeq Acc Id: | XP_017445133 ⟸ XM_017589644 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | O70257 (UniProtKB/Swiss-Prot) |
| - Sequence: |
MSYTPGIGGDPAQLAQRISSNIQKITQCSAEIQRTLNQLGTPQDTPELRQQLQQEQQYTNQLAKhide sequence |
| RefSeq Acc Id: | XP_017445135 ⟸ XM_017589646 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | O70257 (UniProtKB/Swiss-Prot) |
| - Sequence: |
MSYTPGIGGDPAQLAQRISSNIQKITQCSAEIQRTLNQLGTPQDTPELRQQLQQEQQYTNQLAKhide sequence |
| RefSeq Acc Id: | XP_017445134 ⟸ XM_017589645 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | O70257 (UniProtKB/Swiss-Prot) |
| - Sequence: |
MSYTPGIGGDPAQLAQRISSNIQKITQCSAEIQRTLNQLGTPQDTPELRQQLQQEQQYTNQLAKhide sequence |
| RefSeq Acc Id: | ENSRNOP00000021318 ⟸ ENSRNOT00000021318 |
| RefSeq Acc Id: | ENSRNOP00000073994 ⟸ ENSRNOT00000081804 |
Protein Domains
t-SNARE coiled-coil homology
TranscriptomePromoters| RGD ID: | 13689529 | ||||||||
| Promoter ID: | EPDNEW_R53 | ||||||||
| Type: | initiation region | ||||||||
| Name: | Stx7_1 | ||||||||
| Description: | syntaxin 7 | ||||||||
| SO ACC ID: | SO:0000170 | ||||||||
| Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
| Experiment Methods: | Single-end sequencing. | ||||||||
| Position: |
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Strain Variation
Strain Sequence Variants (Rnor 6.0)
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Additional Information
External Database Links| Database | Acc Id | Source(s) |
| AGR Gene | RGD:619747 | AgrOrtholog |
| Ensembl Genes | ENSRNOG00000015670 | Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
| Ensembl Protein | ENSRNOP00000021318 | ENTREZGENE, UniProtKB/Swiss-Prot |
| ENSRNOP00000073994 | UniProtKB/TrEMBL | |
| Ensembl Transcript | ENSRNOT00000021318 | ENTREZGENE, UniProtKB/Swiss-Prot |
| ENSRNOT00000081804 | UniProtKB/TrEMBL | |
| IMAGE_CLONE | IMAGE:7193349 | IMAGE-MGC_LOAD |
| InterPro | SNARE | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
| Syntaxin/epimorphin_CS | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| Syntaxin_N | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| T_SNARE_dom | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| KEGG Report | rno:60466 | UniProtKB/Swiss-Prot |
| MGC_CLONE | MGC:93455 | IMAGE-MGC_LOAD |
| NCBI Gene | 60466 | ENTREZGENE |
| Pfam | SNARE | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
| Syntaxin_2 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| PhenoGen | Stx7 | PhenoGen |
| PROSITE | SYNTAXIN | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
| T_SNARE | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| SMART | SynN | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
| t_SNARE | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
| Superfamily-SCOP | SSF47661 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
| UniGene | Rn.1993 | ENTREZGENE |
| UniProt | A0A0G2K6Y9_RAT | UniProtKB/TrEMBL |
| O70257 | ENTREZGENE, UniProtKB/Swiss-Prot | |
| UniProt Secondary | Q5U337 | UniProtKB/Swiss-Prot |
Nomenclature History| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
|---|---|---|---|---|---|---|---|
| 2004-02-26 | Stx7 | syntaxin 7 | Symbol and Name status set to approved | 625702 | APPROVED | ||
| 2002-08-07 | Stx7 | syntaxin 7 | Symbol and Name status set to provisional | 70820 | PROVISIONAL |
RGD Curation Notes| Note Type | Note | Reference |
|---|---|---|
| gene_expression | mRNA widely expressed in all tissues | 634188 |
| gene_process | involved with vesicle docking and fusion events with membrane | 634188 |
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| More on Stx7 | |
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Alliance Gene |
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NCBI Gene |
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Ensembl Gene |
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JBrowse: rn5 rn6 |
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NCBI Genome Data Viewer |
| RGD Object Information | |
| RGD ID: | 619747 |
| Created: | 2002-08-06 |
| Species: | Rattus norvegicus |
| Last Modified: | 2020-08-20 |
| Status: | ACTIVE |
