STX7 (syntaxin 7) - Rat Genome Database

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Gene: STX7 (syntaxin 7) Homo sapiens
Analyze
Symbol: STX7
Name: syntaxin 7
RGD ID: 737314
HGNC Page HGNC:11442
Description: Enables chloride channel inhibitor activity and syntaxin binding activity. Involved in several processes, including positive regulation of T cell mediated cytotoxicity; positive regulation of receptor localization to synapse; and regulation of protein localization to plasma membrane. Located in cytoplasmic vesicle; immunological synapse; and perinuclear region of cytoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: syntaxin-7
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386132,445,867 - 132,513,472 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6132,445,867 - 132,513,198 (-)EnsemblGRCh38hg38GRCh38
GRCh376132,767,006 - 132,834,611 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366132,822,848 - 132,875,859 (-)NCBINCBI36Build 36hg18NCBI36
Build 346132,822,847 - 132,875,859NCBI
Celera6133,525,518 - 133,581,174 (-)NCBICelera
Cytogenetic Map6q23.2NCBI
HuRef6130,353,519 - 130,409,169 (-)NCBIHuRef
CHM1_16133,042,339 - 133,098,018 (-)NCBICHM1_1
T2T-CHM13v2.06133,640,859 - 133,708,445 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8619474   PMID:9110174   PMID:9358037   PMID:9417091   PMID:9852078   PMID:10564279   PMID:10692457   PMID:10839363   PMID:10982406   PMID:11031247   PMID:11101518   PMID:11252894  
PMID:11278762   PMID:11382755   PMID:11423532   PMID:11786915   PMID:12114520   PMID:12175335   PMID:12218144   PMID:12477932   PMID:12543931   PMID:12665801   PMID:12730232   PMID:14574404  
PMID:14623309   PMID:15345747   PMID:15489334   PMID:16344560   PMID:17255364   PMID:17897319   PMID:18029348   PMID:18198266   PMID:18570918   PMID:18980942   PMID:19322201   PMID:19557002  
PMID:19714869   PMID:20170677   PMID:20458337   PMID:20562859   PMID:21438968   PMID:21516116   PMID:21873635   PMID:21900206   PMID:22939629   PMID:23246001   PMID:23376485   PMID:23434281  
PMID:24173214   PMID:24550300   PMID:24623722   PMID:24711643   PMID:25416956   PMID:26101353   PMID:26186194   PMID:26344197   PMID:26496610   PMID:26638075   PMID:28514442   PMID:29180619  
PMID:29568061   PMID:29997244   PMID:30021884   PMID:30194290   PMID:30639242   PMID:30659120   PMID:30833792   PMID:31073040   PMID:31536960   PMID:31871319   PMID:32296183   PMID:32913203  
PMID:33112705   PMID:33144569   PMID:33422265   PMID:33452816   PMID:33845483   PMID:33957083   PMID:33961781   PMID:34079125   PMID:34432599   PMID:34597346   PMID:34709727   PMID:35063084  
PMID:35253629   PMID:35271311   PMID:35446349   PMID:35762511   PMID:35831314   PMID:35944360   PMID:36042349   PMID:36215168   PMID:36300783   PMID:36610398   PMID:36949045   PMID:37031804  
PMID:37232246   PMID:37616343   PMID:37827155   PMID:38117590  


Genomics

Comparative Map Data
STX7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386132,445,867 - 132,513,472 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6132,445,867 - 132,513,198 (-)EnsemblGRCh38hg38GRCh38
GRCh376132,767,006 - 132,834,611 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366132,822,848 - 132,875,859 (-)NCBINCBI36Build 36hg18NCBI36
Build 346132,822,847 - 132,875,859NCBI
Celera6133,525,518 - 133,581,174 (-)NCBICelera
Cytogenetic Map6q23.2NCBI
HuRef6130,353,519 - 130,409,169 (-)NCBIHuRef
CHM1_16133,042,339 - 133,098,018 (-)NCBICHM1_1
T2T-CHM13v2.06133,640,859 - 133,708,445 (-)NCBIT2T-CHM13v2.0
Stx7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391024,025,182 - 24,064,859 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1024,025,200 - 24,066,120 (+)EnsemblGRCm39 Ensembl
GRCm381024,149,289 - 24,188,961 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1024,149,302 - 24,190,222 (+)EnsemblGRCm38mm10GRCm38
MGSCv371023,869,123 - 23,908,765 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361023,838,776 - 23,878,375 (+)NCBIMGSCv36mm8
Celera1025,082,517 - 25,122,173 (+)NCBICelera
Cytogenetic Map10A4NCBI
cM Map1011.45NCBI
Stx7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8123,016,330 - 23,056,579 (-)NCBIGRCr8
mRatBN7.2121,197,075 - 21,237,320 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl121,197,075 - 21,237,279 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx120,973,496 - 21,014,331 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0126,973,523 - 27,014,359 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0121,173,353 - 21,214,086 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0122,241,655 - 22,281,850 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl122,241,661 - 22,281,788 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0123,721,812 - 23,762,002 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4121,721,897 - 21,762,024 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1121,724,841 - 21,764,969 (-)NCBI
Celera119,947,867 - 19,987,994 (-)NCBICelera
Cytogenetic Map1p12NCBI
Stx7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495543612,928,274 - 12,975,745 (-)NCBIChiLan1.0ChiLan1.0
STX7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25152,440,392 - 152,495,586 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16150,345,389 - 150,402,661 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06130,232,041 - 130,289,326 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16134,342,305 - 134,397,533 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6134,342,304 - 134,398,215 (-)Ensemblpanpan1.1panPan2
STX7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1125,544,283 - 25,607,179 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl125,546,596 - 25,607,231 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha126,531,632 - 26,594,249 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0125,455,483 - 25,518,496 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl125,458,138 - 25,518,571 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1125,501,729 - 25,564,656 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0125,400,189 - 25,462,818 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0125,663,904 - 25,726,563 (-)NCBIUU_Cfam_GSD_1.0
Stx7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946120,685,451 - 120,733,071 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936560464,617 - 513,009 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936560464,667 - 512,322 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
STX7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl131,184,947 - 31,235,865 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1131,184,905 - 31,237,052 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2134,705,635 - 34,757,859 (+)NCBISscrofa10.2Sscrofa10.2susScr3
STX7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11341,029,992 - 41,086,589 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1341,030,073 - 41,088,308 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604013,220,150 - 13,275,468 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Stx7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247536,514,056 - 6,547,480 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247536,511,516 - 6,554,406 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in STX7
12 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 6q23.2(chr6:132455272-133141153)x3 copy number gain See cases [RCV000053388] Chr6:132455272..133141153 [GRCh38]
Chr6:132776411..133462292 [GRCh37]
Chr6:132818104..133503985 [NCBI36]
Chr6:6q23.2		 uncertain significance
GRCh38/hg38 6q13-24.1(chr6:74382807-142040500)x3 copy number gain See cases [RCV000139729] Chr6:74382807..142040500 [GRCh38]
Chr6:75092523..142361637 [GRCh37]
Chr6:75149243..142403330 [NCBI36]
Chr6:6q13-24.1		 pathogenic
GRCh38/hg38 6q22.32-23.2(chr6:126494533-132497855)x1 copy number loss See cases [RCV000142805] Chr6:126494533..132497855 [GRCh38]
Chr6:126815679..132818994 [GRCh37]
Chr6:126857372..132860687 [NCBI36]
Chr6:6q22.32-23.2		 likely pathogenic
NM_003569.3(STX7):c.159A>C (p.Gln53His) single nucleotide variant Abnormality of neuronal migration [RCV000203258] Chr6:132472372 [GRCh38]
Chr6:132793511 [GRCh37]
Chr6:6q23.2		 pathogenic|likely pathogenic
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482)x3 copy number gain See cases [RCV000512067] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482) copy number gain See cases [RCV000510595] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
GRCh37/hg19 6q23.2-23.3(chr6:131388023-137469640)x1 copy number loss not provided [RCV000682724] Chr6:131388023..137469640 [GRCh37]
Chr6:6q23.2-23.3		 pathogenic
GRCh37/hg19 6q23.2-23.3(chr6:132002460-137160850)x1 copy number loss not provided [RCV000682725] Chr6:132002460..137160850 [GRCh37]
Chr6:6q23.2-23.3		 pathogenic
GRCh37/hg19 6p25.3-q27(chr6:60107-171054786)x3 copy number gain not provided [RCV000745400] Chr6:60107..171054786 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
GRCh37/hg19 6p25.3-q27(chr6:108666-170980171)x3 copy number gain not provided [RCV000745403] Chr6:108666..170980171 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
GRCh37/hg19 6p25.3-q27(chr6:165632-170919470)x3 copy number gain not provided [RCV000745404] Chr6:165632..170919470 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
GRCh37/hg19 6q23.2(chr6:132794904-132879258)x3 copy number gain not provided [RCV000746039] Chr6:132794904..132879258 [GRCh37]
Chr6:6q23.2		 benign
Single allele deletion Interstitial 6q microdeletion syndrome [RCV002280353] Chr6:115941808..133892653 [GRCh38]
Chr6:6q22.1-23.2		 pathogenic
GRCh37/hg19 6q23.1-23.3(chr6:130769034-136009217)x1 copy number loss not provided [RCV001829086] Chr6:130769034..136009217 [GRCh37]
Chr6:6q23.1-23.3		 pathogenic
NM_003569.3(STX7):c.170A>G (p.Gln57Arg) single nucleotide variant Inborn genetic diseases [RCV002817494] Chr6:132472361 [GRCh38]
Chr6:132793500 [GRCh37]
Chr6:6q23.2		 uncertain significance
NM_003569.3(STX7):c.253C>G (p.Gln85Glu) single nucleotide variant Inborn genetic diseases [RCV002803432] Chr6:132471597 [GRCh38]
Chr6:132792736 [GRCh37]
Chr6:6q23.2		 uncertain significance
NM_003569.3(STX7):c.497G>A (p.Arg166His) single nucleotide variant Inborn genetic diseases [RCV002665512] Chr6:132469991 [GRCh38]
Chr6:132791130 [GRCh37]
Chr6:6q23.2		 uncertain significance
NM_003569.3(STX7):c.307A>G (p.Asn103Asp) single nucleotide variant Inborn genetic diseases [RCV003283165] Chr6:132471543 [GRCh38]
Chr6:132792682 [GRCh37]
Chr6:6q23.2		 uncertain significance
NM_003569.3(STX7):c.14C>T (p.Pro5Leu) single nucleotide variant Inborn genetic diseases [RCV003371623] Chr6:132503517 [GRCh38]
Chr6:132824656 [GRCh37]
Chr6:6q23.2		 uncertain significance
GRCh37/hg19 6q22.31-23.3(chr6:120218852-137160850)x1 copy number loss not provided [RCV003482930] Chr6:120218852..137160850 [GRCh37]
Chr6:6q22.31-23.3		 pathogenic
GRCh37/hg19 6q23.2-24.2(chr6:131569837-145572239)x3 copy number gain not specified [RCV003986663] Chr6:131569837..145572239 [GRCh37]
Chr6:6q23.2-24.2		 pathogenic
GRCh37/hg19 6q22.31-25.3(chr6:119840686-156623091)x3 copy number gain not specified [RCV003986631] Chr6:119840686..156623091 [GRCh37]
Chr6:6q22.31-25.3		 pathogenic
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:5218
Count of miRNA genes:1314
Interacting mature miRNAs:1722
Transcripts:ENST00000367937, ENST00000367941, ENST00000448348, ENST00000475879
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
STS-W94888  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376132,779,014 - 132,779,204UniSTSGRCh37
Build 366132,820,707 - 132,820,897RGDNCBI36
Celera6133,525,869 - 133,526,059RGD
Cytogenetic Map6q23.1UniSTS
HuRef6130,353,870 - 130,354,060UniSTS
GeneMap99-GB4 RH Map6538.94UniSTS
NCBI RH Map61538.9UniSTS
RH92707  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376132,778,888 - 132,778,969UniSTSGRCh37
Build 366132,820,581 - 132,820,662RGDNCBI36
Celera6133,525,743 - 133,525,824RGD
Cytogenetic Map6q23.1UniSTS
HuRef6130,353,744 - 130,353,825UniSTS
GeneMap99-GB4 RH Map6532.92UniSTS
RH93946  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376132,779,734 - 132,779,902UniSTSGRCh37
Build 366132,821,427 - 132,821,595RGDNCBI36
Celera6133,526,589 - 133,526,757RGD
Cytogenetic Map6q23.1UniSTS
HuRef6130,354,590 - 130,354,758UniSTS
GeneMap99-GB4 RH Map6532.92UniSTS
RH103341  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376132,779,183 - 132,779,334UniSTSGRCh37
Build 366132,820,876 - 132,821,027RGDNCBI36
Celera6133,526,038 - 133,526,189RGD
Cytogenetic Map6q23.1UniSTS
HuRef6130,354,039 - 130,354,190UniSTS
GeneMap99-GB4 RH Map6532.81UniSTS
RH121178  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376132,792,171 - 132,792,463UniSTSGRCh37
Build 366132,833,864 - 132,834,156RGDNCBI36
Celera6133,539,019 - 133,539,311RGD
Cytogenetic Map6q23.1UniSTS
HuRef6130,367,013 - 130,367,305UniSTS
TNG Radiation Hybrid Map665683.0UniSTS
D6S957  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376132,812,001 - 132,812,214UniSTSGRCh37
Build 366132,853,694 - 132,853,907RGDNCBI36
Celera6133,558,849 - 133,559,067RGD
Cytogenetic Map6q23.1UniSTS
HuRef6130,386,847 - 130,387,060UniSTS
G28630  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376132,834,646 - 132,834,762UniSTSGRCh37
Build 366132,876,339 - 132,876,455RGDNCBI36
Celera6133,581,483 - 133,581,599RGD
Cytogenetic Map6q23.1UniSTS
HuRef6130,409,478 - 130,409,594UniSTS
SHGC-155523  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376132,801,636 - 132,801,912UniSTSGRCh37
Build 366132,843,329 - 132,843,605RGDNCBI36
Celera6133,548,485 - 133,548,761RGD
Cytogenetic Map6q23.1UniSTS
TNG Radiation Hybrid MapX1349.0UniSTS
RH46764  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376132,780,720 - 132,780,900UniSTSGRCh37
Build 366132,822,413 - 132,822,593RGDNCBI36
Celera6133,527,575 - 133,527,755RGD
Cytogenetic Map6q23.1UniSTS
HuRef6130,355,576 - 130,355,756UniSTS
GeneMap99-GB4 RH Map6532.92UniSTS
NCBI RH Map61538.9UniSTS
A009O06  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376132,823,323 - 132,823,430UniSTSGRCh37
Build 366132,865,016 - 132,865,123RGDNCBI36
Celera6133,570,180 - 133,570,287RGD
Cytogenetic Map6q23.1UniSTS
HuRef6130,398,173 - 130,398,280UniSTS
GeneMap99-GB4 RH Map6537.1UniSTS
NCBI RH Map61538.9UniSTS
WI-17521  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376132,780,670 - 132,780,776UniSTSGRCh37
Build 366132,822,363 - 132,822,469RGDNCBI36
Celera6133,527,525 - 133,527,631RGD
Cytogenetic Map6q23.1UniSTS
HuRef6130,355,526 - 130,355,632UniSTS
GeneMap99-GB4 RH Map6532.92UniSTS
Whitehead-RH Map6756.1UniSTS
NCBI RH Map61538.9UniSTS
RH12578  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376132,794,887 - 132,795,048UniSTSGRCh37
Build 366132,836,580 - 132,836,741RGDNCBI36
Celera6133,541,736 - 133,541,897RGD
Cytogenetic Map6q23.1UniSTS
HuRef6130,369,730 - 130,369,891UniSTS
GeneMap99-GB4 RH Map6533.13UniSTS
D6S2191  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6q23.1UniSTS
HuRef6130,355,971 - 130,356,112UniSTS
G32698  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376132,823,323 - 132,823,430UniSTSGRCh37
Celera6133,570,180 - 133,570,287UniSTS
Cytogenetic Map6q23.1UniSTS
HuRef6130,398,173 - 130,398,280UniSTS
RH46806  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6q23.1UniSTS
HuRef6130,355,971 - 130,356,080UniSTS
GeneMap99-GB4 RH Map6532.92UniSTS
NCBI RH Map61538.9UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 1370 1496 693 100 1242 52 2651 695 1680 247 692 1276 61 1 930 1587 4 2
Low 1069 1491 1033 524 707 413 1706 1499 2054 172 768 337 114 274 1201 2
Below cutoff 4 1 3

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_050740 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001326578 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001326579 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001326580 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_003569 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_137169 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF131808 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ420529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK294911 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK301464 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL357034 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL589691 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW500305 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC011975 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BF064142 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068272 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA242979 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KF458280 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U77942 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000367937   ⟹   ENSP00000356914
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl6132,461,714 - 132,513,198 (-)Ensembl
RefSeq Acc Id: ENST00000367941   ⟹   ENSP00000356918
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl6132,445,867 - 132,513,116 (-)Ensembl
RefSeq Acc Id: ENST00000448348
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl6132,469,994 - 132,513,135 (-)Ensembl
RefSeq Acc Id: ENST00000475879
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl6132,475,280 - 132,513,065 (-)Ensembl
RefSeq Acc Id: NM_001326578   ⟹   NP_001313507
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386132,445,867 - 132,512,783 (-)NCBI
T2T-CHM13v2.06133,640,859 - 133,707,756 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001326579   ⟹   NP_001313508
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386132,445,867 - 132,513,472 (-)NCBI
T2T-CHM13v2.06133,640,859 - 133,708,445 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001326580   ⟹   NP_001313509
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386132,461,474 - 132,513,116 (-)NCBI
T2T-CHM13v2.06133,656,465 - 133,708,089 (-)NCBI
Sequence:
RefSeq Acc Id: NM_003569   ⟹   NP_003560
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386132,445,867 - 132,513,116 (-)NCBI
GRCh376132,778,663 - 132,834,337 (-)ENTREZGENE
Build 366132,822,848 - 132,875,859 (-)NCBI Archive
HuRef6130,353,519 - 130,409,169 (-)ENTREZGENE
CHM1_16133,042,339 - 133,098,018 (-)NCBI
T2T-CHM13v2.06133,640,859 - 133,708,089 (-)NCBI
Sequence:
RefSeq Acc Id: NR_137169
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh386132,445,867 - 132,513,116 (-)NCBI
T2T-CHM13v2.06133,640,859 - 133,708,089 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_003560   ⟸   NM_003569
- Peptide Label: isoform a
- UniProtKB: Q5SZW2 (UniProtKB/Swiss-Prot),   E1P579 (UniProtKB/Swiss-Prot),   Q96ES9 (UniProtKB/Swiss-Prot),   O15400 (UniProtKB/Swiss-Prot),   B4DH37 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001313508   ⟸   NM_001326579
- Peptide Label: isoform a
- UniProtKB: Q5SZW2 (UniProtKB/Swiss-Prot),   E1P579 (UniProtKB/Swiss-Prot),   Q96ES9 (UniProtKB/Swiss-Prot),   O15400 (UniProtKB/Swiss-Prot),   B4DH37 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001313507   ⟸   NM_001326578
- Peptide Label: isoform a
- UniProtKB: Q5SZW2 (UniProtKB/Swiss-Prot),   E1P579 (UniProtKB/Swiss-Prot),   Q96ES9 (UniProtKB/Swiss-Prot),   O15400 (UniProtKB/Swiss-Prot),   B4DH37 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001313509   ⟸   NM_001326580
- Peptide Label: isoform b
- UniProtKB: O15400 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000356918   ⟸   ENST00000367941
RefSeq Acc Id: ENSP00000356914   ⟸   ENST00000367937
Protein Domains
t-SNARE coiled-coil homology

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O15400-F1-model_v2 AlphaFold O15400 1-261 view protein structure

Promoters
RGD ID:7209171
Promoter ID:EPDNEW_H10331
Type:initiation region
Name:STX7_1
Description:syntaxin 7
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh386132,513,116 - 132,513,176EPDNEW
RGD ID:6804824
Promoter ID:HG_KWN:55039
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lymphoblastoid
Transcripts:ENST00000367941
Position:
Human AssemblyChrPosition (strand)Source
Build 366132,867,161 - 132,867,661 (-)MPROMDB
RGD ID:6804827
Promoter ID:HG_KWN:55040
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_003569,   OTTHUMT00000042251,   OTTHUMT00000042253
Position:
Human AssemblyChrPosition (strand)Source
Build 366132,875,506 - 132,876,006 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:11442 AgrOrtholog
COSMIC STX7 COSMIC
Ensembl Genes ENSG00000079950 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000367937 ENTREZGENE
  ENST00000367937.4 UniProtKB/Swiss-Prot
  ENST00000367941 ENTREZGENE
  ENST00000367941.7 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.5.110 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.20.58.70 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000079950 GTEx
HGNC ID HGNC:11442 ENTREZGENE
Human Proteome Map STX7 Human Proteome Map
InterPro SNARE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Syntaxin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Syntaxin/epimorphin_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Syntaxin_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  T_SNARE_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:8417 UniProtKB/Swiss-Prot
NCBI Gene 8417 ENTREZGENE
OMIM 603217 OMIM
PANTHER PTHR19957 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SYNTAXIN-7 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam SNARE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Syntaxin_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA36239 PharmGKB
PROSITE SYNTAXIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  T_SNARE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SynN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  t_SNARE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47661 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt B4DH37 ENTREZGENE, UniProtKB/TrEMBL
  E1P579 ENTREZGENE
  O15400 ENTREZGENE
  Q5SZW2 ENTREZGENE
  Q96ES9 ENTREZGENE
  STX7_HUMAN UniProtKB/Swiss-Prot
UniProt Secondary E1P579 UniProtKB/Swiss-Prot
  Q5SZW2 UniProtKB/Swiss-Prot
  Q96ES9 UniProtKB/Swiss-Prot