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Gene: Ripk2 (receptor-interacting serine-threonine kinase 2) Rattus norvegicus
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Symbol: Ripk2
Name: receptor-interacting serine-threonine kinase 2
Description: Predicted to have several functions, including caspase binding activity; protein domain specific binding activity; and protein homodimerization activity. Predicted to be involved in several processes, including immune response-activating signal transduction; positive regulation of cellular protein metabolic process; and positive regulation of cytokine production. Predicted to localize to several cellular components, including the cytoskeleton; cytosol; and mitochondrion. Orthologous to human RIPK2 (receptor interacting serine/threonine kinase 2); PARTICIPATES IN interleukin-12 signaling pathway; nuclear factor kappa B signaling pathway; neurotrophic factor signaling pathway; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1-chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethyl]benzene; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC362491; receptor (TNFRSF)-interacting serine-threonine kinase 2; receptor-interacting serine/threonine-protein kinase 2
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0529,838,713 - 29,870,390 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl529,838,747 - 29,870,735 (-)Ensembl
Rnor_5.0534,512,111 - 34,543,807 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4530,714,817 - 30,745,941 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1530,715,463 - 30,738,284 (-)NCBI
Celera528,836,598 - 28,867,674 (-)NCBICelera
Cytogenetic Map5q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Ripk2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1309167
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.