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Gene: Acta1 (actin, alpha 1, skeletal muscle) Rattus norvegicus
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Symbol: Acta1
Name: actin, alpha 1, skeletal muscle
Description: Predicted to have ATP binding activity. Involved in several processes, including response to lithium ion; response to steroid hormone; and skeletal muscle fiber adaptation. Predicted to localize to several cellular components, including the actin cytoskeleton; filopodium; and lamellipodium. Human ortholog(s) of this gene implicated in nemaline myopathy 3. Orthologous to human ACTA1 (actin alpha 1, skeletal muscle); INTERACTS WITH (+)-schisandrin B; (R)-noradrenaline; (S)-nicotine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: actin alpha 1; actin alpha 1 skeletal muscle; actin, alpha skeletal muscle; alpha-actin-1
Orthologs:
Homo sapiens (human) : ACTA1 (actin alpha 1, skeletal muscle)  HGNC  Alliance
Mus musculus (house mouse) : Acta1 (actin, alpha 1, skeletal muscle)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Acta1 (actin alpha 1, skeletal muscle)
Pan paniscus (bonobo/pygmy chimpanzee) : ACTA1 (actin alpha 1, skeletal muscle)
Canis lupus familiaris (dog) : ACTA1 (actin alpha 1, skeletal muscle)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Acta1 (actin alpha 1, skeletal muscle)
Sus scrofa (pig) : ACTA1 (actin alpha 1, skeletal muscle)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01956,674,072 - 56,677,084 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1956,674,074 - 56,677,084 (-)Ensembl
Rnor_5.01967,389,899 - 67,392,911 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41954,081,496 - 54,084,508 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11954,086,370 - 54,089,389 (-)NCBI
Celera1951,258,256 - 51,261,324 (-)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Acta1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2025
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.