Prrc2a (proline-rich coiled-coil 2A) - Rat Genome Database

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Gene: Prrc2a (proline-rich coiled-coil 2A) Rattus norvegicus
Analyze
Symbol: Prrc2a
Name: proline-rich coiled-coil 2A
RGD ID: 1303025
Description: Predicted to be involved in cell differentiation. Predicted to be located in cytosol; nucleoplasm; and plasma membrane. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to human PRRC2A (proline rich coiled-coil 2A); INTERACTS WITH 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Bat2; HLA-B associated transcript 2; HLA-B-associated transcript 2; large proline-rich protein BAT2; proline-rich and coiled-coil-containing protein 2A
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2203,658,391 - 3,674,143 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl203,658,695 - 3,674,130 (+)Ensembl
Rnor_6.0205,139,881 - 5,155,371 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl205,139,882 - 5,155,293 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0207,213,139 - 7,228,817 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4203,724,278 - 3,737,795 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1203,724,504 - 3,737,844 (+)NCBI
Celera204,351,502 - 4,365,021 (-)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:15060004   PMID:16641100   PMID:19056867   PMID:19946888   PMID:22658674   PMID:22681889   PMID:29476059  


Genomics

Comparative Map Data
Prrc2a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2203,658,391 - 3,674,143 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl203,658,695 - 3,674,130 (+)Ensembl
Rnor_6.0205,139,881 - 5,155,371 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl205,139,882 - 5,155,293 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0207,213,139 - 7,228,817 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4203,724,278 - 3,737,795 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1203,724,504 - 3,737,844 (+)NCBI
Celera204,351,502 - 4,365,021 (-)NCBICelera
Cytogenetic Map20p12NCBI
PRRC2A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38631,620,715 - 31,637,771 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl631,620,715 - 31,637,771 (+)EnsemblGRCh38hg38GRCh38
GRCh37631,588,492 - 31,605,548 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36631,696,429 - 31,713,533 (+)NCBINCBI36hg18NCBI36
Build 34631,696,575 - 31,713,516NCBI
Celera633,186,676 - 33,203,776 (+)NCBI
Cytogenetic Map6p21.33NCBI
HuRef631,374,625 - 31,391,727 (+)NCBIHuRef
CHM1_1631,590,586 - 31,607,690 (+)NCBICHM1_1
T2T-CHM13v2.0631,473,760 - 31,490,814 (+)NCBI
Prrc2a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391735,368,052 - 35,384,877 (-)NCBIGRCm39mm39
GRCm39 Ensembl1735,368,052 - 35,383,873 (-)Ensembl
GRCm381735,149,076 - 35,165,321 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1735,149,076 - 35,164,897 (-)EnsemblGRCm38mm10GRCm38
MGSCv371735,286,021 - 35,299,993 (-)NCBIGRCm37mm9NCBIm37
MGSCv361734,757,317 - 34,771,039 (-)NCBImm8
Celera1738,246,015 - 38,259,986 (-)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1718.59NCBI
Prrc2a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955437163,714 - 176,517 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955437161,618 - 176,225 (+)NCBIChiLan1.0ChiLan1.0
PRRC2A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1632,171,616 - 32,188,738 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl632,171,621 - 32,188,729 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0631,281,722 - 31,298,825 (+)NCBIMhudiblu_PPA_v0panPan3
PRRC2A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1121,110,627 - 1,125,535 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl121,112,614 - 1,125,443 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha121,246,702 - 1,261,980 (+)NCBI
ROS_Cfam_1.0121,255,501 - 1,270,769 (+)NCBI
ROS_Cfam_1.0 Ensembl121,255,865 - 1,270,757 (+)Ensembl
UMICH_Zoey_3.1121,115,163 - 1,130,162 (+)NCBI
UNSW_CanFamBas_1.0121,182,120 - 1,197,395 (+)NCBI
UU_Cfam_GSD_1.0121,249,182 - 1,264,483 (+)NCBI
Prrc2a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494635,659,538 - 35,674,896 (+)NCBI
SpeTri2.0NW_0049367271,886,457 - 1,901,832 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRRC2A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl723,740,144 - 23,756,066 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1723,742,302 - 23,755,950 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2727,495,908 - 27,511,744 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PRRC2A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366604431,530,849 - 31,547,970 (+)NCBIVero_WHO_p1.0
Prrc2a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475424,572,546 - 24,584,643 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462475424,572,178 - 24,586,696 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
MARC_11957-11958:1003854518:1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2203,662,991 - 3,663,548 (-)MAPPERmRatBN7.2
Rnor_6.0205,150,472 - 5,151,028NCBIRnor6.0
Rnor_5.0207,223,731 - 7,224,287UniSTSRnor5.0
RGSC_v3.4203,726,649 - 3,727,205UniSTSRGSC3.4
Celera204,362,093 - 4,362,649UniSTS
Cytogenetic Map20p12UniSTS
MARC_5045-5046:996690083:1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2203,672,619 - 3,673,182 (-)MAPPERmRatBN7.2
Rnor_6.0205,140,838 - 5,141,400NCBIRnor6.0
Rnor_5.0207,214,097 - 7,214,659UniSTSRnor5.0
RGSC_v3.4203,736,277 - 3,736,839UniSTSRGSC3.4
Celera204,352,458 - 4,353,020UniSTS
Cytogenetic Map20p12UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124159021Rat
1600382Edcs3Endometrial carcinoma susceptibility QTL33.50.003uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)20125159026Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129191651Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129191651Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129191651Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129191651Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129191651Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578807Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600972Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600972Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20152784246527842Rat
2306850Pia40Pristane induced arthritis QTL 400.0001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)2015279595304575Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20153065546530655Rat
1598816Memor12Memory QTL 122.4exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)20260683647606836Rat
61448Ciaa1CIA Autoantibody QTL 1300.001blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)2026463954597031Rat
61472Aia1Adjuvant induced arthritis QTL 1180.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)2026463954597031Rat
2317057Aia27Adjuvant induced arthritis QTL 272.83joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)20289259726381954Rat
1300152Bp195Blood pressure QTL 1953.46arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2036216499243559Rat
1331772Cdexp2CD45RC expression in CD8 T cells QTL 25.7CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)20362164910078919Rat
737973Pia21Pristane induced arthritis QTL 214.8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)2036216564606812Rat
61432Cia1Collagen induced arthritis QTL 1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)20362165614101050Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:103
Count of miRNA genes:90
Interacting mature miRNAs:95
Transcripts:ENSRNOT00000001133
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 36 49 33 19 33 1 4 71 33 41 11 1
Low 7 8 8 8 7 7 3 2 7
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000001133   ⟹   ENSRNOP00000001133
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl203,658,695 - 3,674,023 (+)Ensembl
Rnor_6.0 Ensembl205,139,890 - 5,153,399 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000092322   ⟹   ENSRNOP00000075873
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl203,658,695 - 3,674,130 (+)Ensembl
Rnor_6.0 Ensembl205,139,882 - 5,155,293 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000092646   ⟹   ENSRNOP00000075902
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl205,139,882 - 5,140,304 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000111770   ⟹   ENSRNOP00000078944
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl203,658,725 - 3,674,130 (+)Ensembl
RefSeq Acc Id: NM_212462   ⟹   NP_997627
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2203,660,621 - 3,674,138 (+)NCBI
Rnor_6.0205,139,882 - 5,153,399 (-)NCBI
Rnor_5.0207,213,139 - 7,228,817 (-)NCBI
RGSC_v3.4203,724,278 - 3,737,795 (+)RGD
Celera204,351,502 - 4,365,021 (-)RGD
Sequence:
RefSeq Acc Id: XM_006256048   ⟹   XP_006256110
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2203,658,639 - 3,674,143 (+)NCBI
Rnor_6.0205,139,881 - 5,155,371 (-)NCBI
Rnor_5.0207,213,139 - 7,228,817 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006256050   ⟹   XP_006256112
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2203,658,639 - 3,674,143 (+)NCBI
Rnor_6.0205,139,881 - 5,155,371 (-)NCBI
Rnor_5.0207,213,139 - 7,228,817 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006256051   ⟹   XP_006256113
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2203,658,640 - 3,674,143 (+)NCBI
Rnor_6.0205,139,881 - 5,155,370 (-)NCBI
Rnor_5.0207,213,139 - 7,228,817 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006256052   ⟹   XP_006256114
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2203,658,640 - 3,674,130 (+)NCBI
Rnor_6.0205,139,881 - 5,155,370 (-)NCBI
Rnor_5.0207,213,139 - 7,228,817 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006256053   ⟹   XP_006256115
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2203,658,638 - 3,674,138 (+)NCBI
Rnor_6.0205,139,881 - 5,155,371 (-)NCBI
Rnor_5.0207,213,139 - 7,228,817 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039098488   ⟹   XP_038954416
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2203,658,391 - 3,674,143 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_997627   ⟸   NM_212462
- UniProtKB: Q6MG48 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006256114   ⟸   XM_006256052
- Peptide Label: isoform X4
- UniProtKB: Q6MG48 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006256112   ⟸   XM_006256050
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006256115   ⟸   XM_006256053
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_006256110   ⟸   XM_006256048
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006256113   ⟸   XM_006256051
- Peptide Label: isoform X3
- UniProtKB: A0A0U1RRZ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000075873   ⟸   ENSRNOT00000092322
RefSeq Acc Id: ENSRNOP00000075902   ⟸   ENSRNOT00000092646
RefSeq Acc Id: ENSRNOP00000001133   ⟸   ENSRNOT00000001133
RefSeq Acc Id: XP_038954416   ⟸   XM_039098488
- Peptide Label: isoform X1
RefSeq Acc Id: ENSRNOP00000078944   ⟸   ENSRNOT00000111770
Protein Domains
BAT2_N

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6MG48-F1-model_v2 AlphaFold Q6MG48 1-2161 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701400
Promoter ID:EPDNEW_R11922
Type:multiple initiation site
Name:Prrc2a_1
Description:proline-rich coiled-coil 2A
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0205,155,317 - 5,155,377EPDNEW

Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Damaging Variants


Assembly: Rnor_6.0
Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
20 5149106 5149107 C T snv ACI/N (MCW), WN/N (MCW), WKY/N (MCW), MR/N (MCW), F344/NRrrc (MCW)
20 5149781 5149782 A C snv WKY/N (MCW), F344/NRrrc (MCW), ACI/N (MCW)
20 5149793 5149794 G A snv MR/N (MCW)
20 5151072 5151073 G A snv Buf/N (MCW)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1303025 AgrOrtholog
BioCyc Gene G2FUF-4653 BioCyc
Ensembl Genes ENSRNOG00000000852 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000001133 UniProtKB/Swiss-Prot
  ENSRNOP00000075873 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000078944 ENTREZGENE
Ensembl Transcript ENSRNOT00000001133 UniProtKB/Swiss-Prot
  ENSRNOT00000092322 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000111770 ENTREZGENE
InterPro BAT2_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PRRC2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:294250 UniProtKB/Swiss-Prot
NCBI Gene 294250 ENTREZGENE
PANTHER PTHR14038 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam BAT2_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Prrc2a PhenoGen
UniProt A0A0U1RRZ5 ENTREZGENE, UniProtKB/TrEMBL
  PRC2A_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-07-28 Prrc2a  proline-rich coiled-coil 2A  Bat2  HLA-B associated transcript 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Bat2  HLA-B associated transcript 2      Symbol and Name status set to approved 1299863 APPROVED
2005-02-14 Bat2  HLA-B associated transcript 2      Symbol and Name status set to provisional 70820 PROVISIONAL