Crip2 (cysteine-rich protein 2) - Rat Genome Database

Name: Crip2
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Crip2 (cysteine-rich protein 2) Rattus norvegicus

Analyze

Symbol:

Crip2

Name:

cysteine-rich protein 2

RGD ID:

1302959

Description:

Predicted to enable metal ion binding activity. Predicted to act upstream of or within hemopoiesis and positive regulation of cell population proliferation. Predicted to be located in cell cortex. Orthologous to human CRIP2 (cysteine rich protein 2); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 17beta-estradiol.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

CRP-2; CRP2; LIM/double zinc-finger protein

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	CRIP2 (cysteine rich protein 2)	HGNC	Ensembl, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Crip2 (cysteine rich protein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Crip2 (cysteine rich protein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	CRIP2 (cysteine rich protein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	CRIP2 (cysteine rich protein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Crip2 (cysteine rich protein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	CRIP2 (cysteine rich protein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	CRIP2 (cysteine rich protein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Crip2 (cysteine rich protein 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	CRIP3 (cysteine rich protein 3)	HGNC	OrthoDB
Homo sapiens (human):	GAB2 (GRB2 associated binding protein 2)	HGNC	OMA
Alliance orthologs ³
Mus musculus (house mouse):	Crip2 (cysteine rich protein 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	CRIP2 (cysteine rich protein 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	zgc:101840	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER)
Danio rerio (zebrafish):	crip2 (cysteine-rich protein 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	mlp-1	Alliance	DIOPT (InParanoid\|OrthoInspector\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	crip2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	6	132,221,120 - 132,226,066 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	132,221,082 - 132,226,065 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	132,390,282 - 132,395,247 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	132,680,431 - 132,685,392 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	132,055,520 - 132,060,465 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	137,953,545 - 137,958,491 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	137,953,545 - 137,958,490 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	146,947,888 - 146,952,833 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	138,147,462 - 138,152,407 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	6	138,153,648 - 138,158,594 (+)	NCBI
Celera	6	129,759,570 - 129,764,515 (+)	NCBI		Celera
Cytogenetic Map	6	q32	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

COVID-19 (ISO)

genetic disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (EXP)

17beta-estradiol (EXP)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (ISO)

2,4,6-tribromophenol (ISO)

2,4-dinitrotoluene (EXP)

3,3',4,4',5-pentachlorobiphenyl (EXP)

3,3',5,5'-tetrabromobisphenol A (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

acrylamide (EXP)

aflatoxin B1 (ISO)

ammonium chloride (EXP)

Aroclor 1254 (EXP)

arsenite(3-) (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

beta-naphthoflavone (ISO)

bisphenol A (EXP,ISO)

bleomycin A2 (EXP)

bortezomib (ISO)

Brodifacoum (EXP)

cadmium dichloride (EXP)

caffeine (ISO)

cantharidin (ISO)

carbon nanotube (ISO)

chlorpyrifos (ISO)

cisplatin (ISO)

clofibric acid (EXP)

cobalt dichloride (ISO)

cocaine (EXP)

copper(II) sulfate (ISO)

coumestrol (ISO)

Cuprizon (EXP)

cyclosporin A (ISO)

decabromodiphenyl ether (ISO)

diazinon (ISO)

doxorubicin (ISO)

endosulfan (EXP)

epoxiconazole (ISO)

ethanol (ISO)

etoposide (ISO)

fipronil (EXP)

flutamide (EXP)

fulvestrant (ISO)

furan (EXP)

genistein (EXP)

hexadecanoic acid (ISO)

hydrogen peroxide (ISO)

ivermectin (ISO)

L-ascorbic acid (EXP)

lead diacetate (EXP)

maneb (ISO)

methoxychlor (EXP)

mitomycin C (ISO)

N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal (ISO)

N-methyl-N-nitrosourea (ISO)

nefazodone (EXP)

nitroglycerin (EXP)

paracetamol (EXP,ISO)

paraquat (ISO)

perfluorooctane-1-sulfonic acid (EXP)

perfluorooctanoic acid (EXP)

phenobarbital (EXP,ISO)

pirinixic acid (EXP,ISO)

potassium chromate (ISO)

pregnenolone 16alpha-carbonitrile (EXP,ISO)

propanal (ISO)

Propiverine (EXP)

resveratrol (ISO)

silicon dioxide (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenite (ISO)

Soman (EXP)

sulforaphane (ISO)

tamoxifen (ISO)

temozolomide (ISO)

testosterone (ISO)

tetrachloromethane (EXP)

tetrahydropalmatine (ISO)

thioacetamide (EXP)

tolcapone (EXP)

trichloroethene (EXP)

triclosan (ISO)

triphenyl phosphate (EXP)

Triptolide (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

hemopoiesis (ISO)

positive regulation of cell population proliferation (ISO)

Cellular Component

cell cortex (ISO)

Molecular Function

metal ion binding (IEA)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
2.	Cloning of CRP2, a novel member of the cysteine-rich protein family with two repeats of an unusual LIM/double zinc-finger motif.	Okano I, etal., FEBS Lett 1993 Oct 25;333(1-2):51-5.
3.	GOA pipeline	RGD automated data pipeline
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
5.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:11740862	PMID:12839623	PMID:15489334	PMID:19364329	PMID:20551380

Genomics

Comparative Map Data

Crip2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	6	132,221,120 - 132,226,066 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	132,221,082 - 132,226,065 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	132,390,282 - 132,395,247 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	132,680,431 - 132,685,392 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	132,055,520 - 132,060,465 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	137,953,545 - 137,958,491 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	137,953,545 - 137,958,490 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	146,947,888 - 146,952,833 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	138,147,462 - 138,152,407 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	6	138,153,648 - 138,158,594 (+)	NCBI
Celera	6	129,759,570 - 129,764,515 (+)	NCBI		Celera
Cytogenetic Map	6	q32	NCBI

CRIP2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	105,472,945 - 105,480,170 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	105,472,962 - 105,480,162 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	14	105,939,282 - 105,946,507 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	105,012,176 - 105,017,545 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	14	105,012,175 - 105,017,545	NCBI
Celera	14	85,990,016 - 85,997,894 (+)	NCBI		Celera
Cytogenetic Map	14	q32.33	NCBI
HuRef	14	86,135,124 - 86,144,668 (+)	NCBI		HuRef
CHM1_1	14	105,876,138 - 105,884,225 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	14	99,720,088 - 99,729,539 (+)	NCBI		T2T-CHM13v2.0

Crip2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	113,103,856 - 113,109,126 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	113,103,856 - 113,109,126 (+)	Ensembl		GRCm39 Ensembl
GRCm38	12	113,140,236 - 113,145,506 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	113,140,236 - 113,145,506 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	12	114,378,447 - 114,383,717 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	12	113,588,355 - 113,593,314 (+)	NCBI		MGSCv36	mm8
Celera	12	114,356,079 - 114,361,349 (+)	NCBI		Celera
Cytogenetic Map	12	F1	NCBI
cM Map	12	61.57	NCBI

Crip2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955538	3,673,482 - 3,680,424 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955538	3,673,452 - 3,683,384 (+)	NCBI	ChiLan1.0	ChiLan1.0

CRIP2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	14	105,868,660 - 105,884,588 (+)	NCBI		NHGRI_mPanPan1

CRIP2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	8	72,774,506 - 72,779,009 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	8	72,773,451 - 72,778,949 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	8	72,284,684 - 72,289,197 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	8	73,062,462 - 73,066,955 (+)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	8	72,743,175 - 72,747,654 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	8	72,790,443 - 72,795,507 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	8	73,182,443 - 73,186,962 (+)	NCBI		UU_Cfam_GSD_1.0

Crip2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	1,280,492 - 1,285,348 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936621	109,401 - 114,311 (-)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936621	109,449 - 114,305 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CRIP2
(Sus scrofa - pig)

No map positions available.

CRIP2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	83,372,691 - 83,378,180 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	24	83,372,334 - 83,378,215 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666053	70,830,272 - 70,836,840 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Crip2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624734	61,443 - 66,232 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624734	61,557 - 66,267 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Crip2
17 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	316
Count of miRNA genes:	178
Interacting mature miRNAs:	200
Transcripts:	ENSRNOT00000006804
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
731173	Uae22	Urinary albumin excretion QTL 22	10.1		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	65531555	140994061	Rat
2290393	Uae37	Urinary albumin excretion QTL 37		0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	65531555	140994061	Rat
724513	Uae14	Urinary albumin excretion QTL 14	6.5		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	85311061	133478515	Rat
2303624	Vencon5	Ventilatory control QTL 5	4.45		respiration trait (VT:0001943)	minute ventilation (CMO:0000132)	6	88047916	133047916	Rat
61414	Pia3	Pristane induced arthritis QTL 3	4.5		joint integrity trait (VT:0010548)	post-insult time to onset of experimental arthritis (CMO:0001450)	6	94968928	137848904	Rat
12801411	Schws8	Schwannoma susceptibility QTL 8			nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	6	94968928	139968928	Rat
8552796	Vie3	Viral induced encephalitis QTL 3	2.6		brain integrity trait (VT:0010579)	encephalitis incidence/prevalence measurement (CMO:0002361)	6	96833997	140994061	Rat
1358355	Srcrt4	Stress Responsive Cort QTL 4	6.39		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	6	100364669	140994061	Rat
2313399	Anxrr28	Anxiety related response QTL 28			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	6	100671796	132340886	Rat
71111	Iddm8	Insulin dependent diabetes mellitus QTL 8	1.9	0.002	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	6	105156861	140994061	Rat
4145118	Mcs26	Mammary carcinoma susceptibility QTL 26		0.0001	mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	6	106752656	132339866	Rat
737976	Pia24	Pristane induced arthritis QTL 24			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	6	112636280	140994061	Rat
1641917	Colcr5	Colorectal carcinoma resistance QTL 5	3.18	0.0009	intestine integrity trait (VT:0010554)	benign colorectal tumor number (CMO:0001795)	6	122549046	137801795	Rat
2293085	Iddm29	Insulin dependent diabetes mellitus QTL 29	7.66		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	6	122549046	140286318	Rat
61329	Eae9	Experimental allergic encephalomyelitis QTL 9	3.7		body mass (VT:0001259)	change in body weight (CMO:0002045)	6	122549046	140994061	Rat
2312560	Pur20	Proteinuria QTL 20	2.1	0.005	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	6	125628133	137801795	Rat

Markers in Region

RH127355

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	X	16,094,614 - 16,094,816 (+)	MAPPER	mRatBN7.2
mRatBN7.2	6	132,225,822 - 132,226,023 (+)	MAPPER	mRatBN7.2
Rnor_6.0	6	137,958,248 - 137,958,448	NCBI	Rnor6.0
Rnor_6.0	X	16,947,044 - 16,947,245	NCBI	Rnor6.0
Rnor_5.0	6	146,952,591 - 146,952,791	UniSTS	Rnor5.0
Rnor_5.0	X	17,729,253 - 17,729,454	UniSTS	Rnor5.0
RGSC_v3.4	6	138,152,165 - 138,152,365	UniSTS	RGSC3.4
RGSC_v3.4	X	29,089,767 - 29,089,968	UniSTS	RGSC3.4
Celera	X	16,165,278 - 16,165,479	UniSTS
Celera	6	129,764,273 - 129,764,473	UniSTS
Cytogenetic Map	X	q13	UniSTS
Cytogenetic Map	6	q32	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High		21										1
Medium	3	22	57	41	19	41	8	11	74	35	41	10	8
Low
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_022501	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008764943	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC061774	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474034	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	D17512	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ226314	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ227529	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ230331	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ233584	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000169	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000006804 ⟹ ENSRNOP00000006804

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	132,221,082 - 132,226,063 (+)	Ensembl
Rnor_6.0 Ensembl	6	137,953,545 - 137,958,490 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000108543 ⟹ ENSRNOP00000088659

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	132,223,429 - 132,226,065 (+)	Ensembl

RefSeq Acc Id:

NM_022501 ⟹ NP_071946

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	6	132,221,120 - 132,226,065 (+)	NCBI
Rnor_6.0	6	137,953,545 - 137,958,490 (+)	NCBI
Rnor_5.0	6	146,947,888 - 146,952,833 (+)	NCBI
RGSC_v3.4	6	138,147,462 - 138,152,407 (+)	RGD
Celera	6	129,759,570 - 129,764,515 (+)	RGD

Sequence:

show sequence

CGGCGGCGCAGAGAGGAGCGCGGGTGGAGGGCGCGGACCGACCGAGCGCACCGACCATGGCCTC
CAAGTGTCCCAAGTGTGACAAGACCGTGTACTTCGCCGAGAAGGTGAGCTCCCTGGGCAAGGAC
TGGCACAAGTTCTGCCTCAAGTGTGAGCGCTGCAACAAGACACTGACGCCTGGCGGCCATGCTG
AGCATGATGGGAAACCCTTCTGCCACAAGCCCTGTTATGCCACACTGTTTGGACCCAAAGGCGT
GAATATCGGGGGCGCTGGTTCCTACATCTACGAGAAGCCTCCGACGGAGGCCCCTCAGGTCACT
GGCCCCATCGAGGTCCCTGTGGTACGAACTGAAGAGCGGAAGACCAGCGGGCCGCCCAAGGGTC
CCAGCAAAGCCTCTAGTGTCACCACGTTCACTGGGGAGCCCAACATGTGCCCTCGATGCAACAA
GAGAGTGTACTTCGCTGAGAAGGTGACCTCCCTGGGCAAGGACTGGCACCGACCCTGCCTGCGC
TGTGAGCGCTGCTCCAAGACACTGACCCCAGGCGGGCATGCTGAGCATGATGGCCAACCCTACT
GCCACAAGCCCTGCTATGGAATACTCTTTGGACCCAAAGGAGTGAATACTGGTGCTGTGGGCAG
CTACATCTACGACAAGGACCCGGAAGGCACAGTTCAGCCTTAGATCTGCAGATGCTGCCCCTCG
CGGTCCCCTATTTGACCCTGAGGGAGAGTGATCTGCTGCCTAGTCCTGCCTCAGTGTGTCTCGC
CTGCAATTCCAGCACCTAAGTGATGGAGGAGAAAGCCCAGCTAGTCCTAGAATTTCAGCTCCCT
TGGTCACCTTGGCATGTCCTATGTTGCCCGTGGTTTACTTTCTGTCTGTGTGTCTCCATAGCAC
CATGGGTCCTGTGTCCCCATGTCCCTGATAACTCTCCAAGGTGGCTGTCCTATGATATCCCTTT
GCCCACACTCGCCCGCCAGTATTATTTATGCTCTGCTTGCCGGTGATGGGCATGAGCTAGCTCA
CAGCATTCCCGGGGTGACGGCACCCCAGCAAGGAGCCCTTTGCTGGTTCCCACACTACTCCCTA
CTTACCCTCACATGGTTCACAGCTATGGAGATTTGCTGTCAATAAATAGTTTGGTTTAAAGATT
GC

hide sequence

RefSeq Acc Id:

XM_008764943 ⟹ XP_008763165

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	6	132,223,473 - 132,226,066 (+)	NCBI
Rnor_6.0	6	137,955,898 - 137,958,491 (+)	NCBI

Sequence:

show sequence

CTTTTCCTGCCTTACTCCCTTGGGGAGGCCCAGGCTTCCGTCCATTGGGATGTGGCTTAGCAGT
CATTGCCCTGGCCATGGCGGGGTGGGGTCCACAACCCTCAGCTGCTGGTCGCAAACCTTTGGCG
CCAAACTGGCAGCTGGAGGCAGTGGGTGGAGGGAGAGACCTCAGGGCTTAGGATGAGGAAACCA
AATAGGGATCTTTCCTGGTGGTCCTGCGGCCGTGTTCCCTCACCTGGTGCTGAAGATCAAGGGC
TTTTCTCTTGGCGGTGGGACTCTGCCTGGCTCTGTGGGGAGGGAGAGAGGTGTGAGGAGACCAC
CGTGGGGGTGAGGCAGGGATTTTGAGGAACAAGGTATAAATAGCCGAGAAGGTGAGCTCCCTGG
GCAAGGACTGGCACAAGTTCTGCCTCAAGTGTGAGCGCTGCAACAAGACACTGACGCCTGGCGG
CCATGCTGAGCATGATGGGAAACCCTTCTGCCACAAGCCCTGTTATGCCACACTGTTTGGACCC
AAAGGCGTGAATATCGGGGGCGCTGGTTCCTACATCTACGAGAAGCCTCCGACGGAGGCCCCTC
AGGTCACTGGCCCCATCGAGGTCCCTGTGGTACGAACTGAAGAGCGGAAGACCAGCGGGCCGCC
CAAGGGTCCCAGCAAAGCCTCTAGTGTCACCACGTTCACTGGGGAGCCCAACATGTGCCCTCGA
TGCAACAAGAGAGTGTACTTCGCTGAGAAGGTGACCTCCCTGGGCAAGGACTGGCACCGACCCT
GCCTGCGCTGTGAGCGCTGCTCCAAGACACTGACCCCAGGCGGGCATGCTGAGCATGATGGCCA
ACCCTACTGCCACAAGCCCTGCTATGGAATACTCTTTGGACCCAAAGGAGTGAATACTGGTGCT
GTGGGCAGCTACATCTACGACAAGGACCCGGAAGGCACAGTTCAGCCTTAGATCTGCAGATGCT
GCCCCTCGCGGTCCCCTATTTGACCCTGAGGGAGAGTGACCTGCTGCCTAGTCCTGCCTCAGTG
TGTCTCGCCTGCAATTCCAGCACCTAAGTGATGGAGGAGAAAGCCCAGCTAGTCCTAGAATTTC
AGCTCCCTTGGTCACCTTGGCATGTCCTATGTTGCCCGTGGTTTACTTTCTGTCTGTGTGTCTC
CATAGCACCATGGGTCCTGTGTCCCCATGTCCCTGATAACTCTCCAAGGTGGCTGTCCTATGAT
ATCCCTTTGCCCACACTCGCCCGCCAGTATTATTTATGCTCTGCTTGCCGGTGATGGGCATGAG
CTAGCTCACAGCATTCCCGGGGTGACGGCACCCCAGCAAGGAGCCCTTTGCTGGTTCCCACACT
ACTCCCTACTTACCCTCACATGGTTCACAGCTATGGAGATTTGCTGTCAATAAATAGTTTGGTT
TAAAGATTGCA

hide sequence

Protein Sequences


Protein RefSeqs	NP_071946	(Get FASTA)	NCBI Sequence Viewer
	XP_008763165	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH61774	(Get FASTA)	NCBI Sequence Viewer
	BAA04464	(Get FASTA)	NCBI Sequence Viewer
	EDL97394	(Get FASTA)	NCBI Sequence Viewer
	EDL97395	(Get FASTA)	NCBI Sequence Viewer
	EDL97396	(Get FASTA)	NCBI Sequence Viewer
	P36201	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_071946 ⟸ NM_022501

- UniProtKB:

P36201 (UniProtKB/Swiss-Prot), A6KBY2 (UniProtKB/TrEMBL), A0A8I6A6Z5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MASKCPKCDKTVYFAEKVSSLGKDWHKFCLKCERCNKTLTPGGHAEHDGKPFCHKPCYATLFGP
KGVNIGGAGSYIYEKPPTEAPQVTGPIEVPVVRTEERKTSGPPKGPSKASSVTTFTGEPNMCPR
CNKRVYFAEKVTSLGKDWHRPCLRCERCSKTLTPGGHAEHDGQPYCHKPCYGILFGPKGVNTGA
VGSYIYDKDPEGTVQP

hide sequence

RefSeq Acc Id:	XP_008763165 ⟸ XM_008764943
- Peptide Label:	isoform X1
- UniProtKB:	A6KBY6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MCPRCNKRVYFAEKVTSLGKDWHRPCLRCERCSKTLTPGGHAEHDGQPYCHKPCYGILFGPKGV NTGAVGSYIYDKDPEGTVQP hide sequence

RefSeq Acc Id:

ENSRNOP00000006804 ⟸ ENSRNOT00000006804

RefSeq Acc Id:

ENSRNOP00000088659 ⟸ ENSRNOT00000108543

Protein Domains

LIM zinc-binding

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P36201-F1-model_v2	AlphaFold	P36201	1-208	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1302959	AgrOrtholog
BioCyc Gene	G2FUF-35762	BioCyc
Ensembl Genes	ENSRNOG00000005041	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000006804	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSRNOP00000088659.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000006804	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSRNOT00000108543.1	UniProtKB/TrEMBL
Gene3D-CATH	Cysteine Rich Protein	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:5621903	IMAGE-MGC_LOAD
InterPro	Znf_LIM	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:338401	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:72447	IMAGE-MGC_LOAD
NCBI Gene	338401	ENTREZGENE
PANTHER	CYSTEINE-RICH PROTEIN 2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	CYSTEINE-RICH PROTEIN CRIP FAMILY MEMBER	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	LIM	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Crip2	PhenoGen
PROSITE	LIM_DOMAIN_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	LIM_DOMAIN_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	LIM	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	Glucocorticoid receptor-like (DNA-binding domain)	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8I6A6Z5	ENTREZGENE, UniProtKB/TrEMBL
	A6KBY2	ENTREZGENE, UniProtKB/TrEMBL
	A6KBY6	ENTREZGENE, UniProtKB/TrEMBL
	CRIP2_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2006-03-30	Crip2	cysteine-rich protein 2			Symbol and Name status set to approved	1299863	APPROVED
2005-02-14	Crip2	cysteine-rich protein 2			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar