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Gene: Ddit4 (DNA-damage-inducible transcript 4) Rattus norvegicus
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Symbol: Ddit4
Name: DNA-damage-inducible transcript 4
Description: Predicted to have 14-3-3 protein binding activity. Involved in several processes, including negative regulation of protein phosphorylation; nervous system development; and neurotrophin TRK receptor signaling pathway. Predicted to localize to cytosol and mitochondrion. Orthologous to human DDIT4 (DNA damage inducible transcript 4); PARTICIPATES IN mTOR signaling pathway; INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 1,2,4-trimethylbenzene; 1,3-dinitrobenzene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: DNA damage-inducible transcript 4 protein; DNA-damage-inducible transcript 4 protein; HIF-1 responsive protein RTP801; HIF-1 responsive RTP801; protein regulated in development and DNA damage response 1; REDD-1; Rtp801
Orthologs:
Homo sapiens (human) : DDIT4 (DNA damage inducible transcript 4)  HGNC  Alliance
Mus musculus (house mouse) : Ddit4 (DNA-damage-inducible transcript 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ddit4 (DNA damage inducible transcript 4)
Pan paniscus (bonobo/pygmy chimpanzee) : DDIT4 (DNA damage inducible transcript 4)
Canis lupus familiaris (dog) : DDIT4 (DNA damage inducible transcript 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ddit4 (DNA damage inducible transcript 4)
Sus scrofa (pig) : DDIT4 (DNA damage inducible transcript 4)
Chlorocebus sabaeus (African green monkey) : DDIT4 (DNA damage inducible transcript 4)
Heterocephalus glaber (naked mole-rat) : Ddit4 (DNA damage inducible transcript 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02029,509,283 - 29,511,382 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2029,509,289 - 29,511,382 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02031,315,024 - 31,317,123 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42027,252,273 - 27,254,371 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12027,266,073 - 27,268,171 (-)NCBI
Celera2029,333,162 - 29,335,357 (-)NCBICelera
Cytogenetic Map20q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Ddit4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621731
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.