Gene: Tnf (tumor necrosis factor) Rattus norvegicus
Symbol: Tnf
Name: tumor necrosis factor
Description: ENCODES a protein that exhibits RNA polymerase II regulatory region sequence-specific DNA binding; tumor necrosis factor receptor binding; cytokine activity (ortholog); INVOLVED IN acute inflammatory response; apoptotic process; calcium-mediated signaling; PARTICIPATES IN tumor necrosis factor mediated signaling pathway; ceramide signaling pathway; Fc epsilon receptor mediated signaling pathway; ASSOCIATED WITH altered response to myocardial infarction; decreased heart rate; decreased vasodilation; ASSOCIATED WITH Acute Liver Failure; Acute Lung Injury; Albuminuria; FOUND IN external side of plasma membrane; extracellular space; cell surface (ortholog); INTERACTS WITH (+)-alpha-tocopherol; (+)-catechin; (+)-pilocarpine
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: cachectin; MGC124630; RATTNF; TNF-a; TNF-alpha; Tnfa; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor ligand superfamily member 2; tumor necrosis factor superfamily member 2; tumor necrosis factor superfamily, member 2; tumor necrosis factor-alpha
Homo sapiens (human) : TNF (tumor necrosis factor)  HGNC  Alliance
Mus musculus (house mouse) : Tnf (tumor necrosis factor)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tnf (tumor necrosis factor)
Pan paniscus (bonobo/pygmy chimpanzee) : TNF (tumor necrosis factor)
Canis lupus familiaris (dog) : TNF (tumor necrosis factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tnf (tumor necrosis factor)
more info ...
Is Marker For: QTLs:   Bp144  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0205,189,382 - 5,192,000 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0206,936,229 - 6,938,847 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4203,661,000 - 3,663,618 (+)NCBIRGSC3.4rn4RGSC3.4
Celera204,400,860 - 4,403,478 (-)NCBICelera
Cytogenetic Map20p12NCBI
RH 3.4 Map20 RGD
JBrowse: View Region in Genome Browser (JBrowse)