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Imported Disease Annotations - ClinVarTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Alzheimer's disease | | ISO | TNF (Homo sapiens) | 8554872 | ClinVar Annotator: match by term: Alzheimer disease and protection against | ClinVar | PMID:10400991 and PMID:16908746 | asthma | | ISO | TNF (Homo sapiens) | 8554872 | ClinVar Annotator: match by term: Asthma and susceptibility to | ClinVar | PMID:10450718 more ... | COVID-19 | | ISO | TNF (Homo sapiens) | 8554872 | ClinVar Annotator: match by term: Susceptibility to severe coronavirus disease (COVID-19) | ClinVar | PMID:10450718 more ... | endometriosis | | ISO | TNF (Homo sapiens) | 8554872 | ClinVar Annotator: match by term: Endometriosis | ClinVar | PMID:10450718 more ... | genetic disease | | ISO | TNF (Homo sapiens) | 8554872 | ClinVar Annotator: match by term: Inborn genetic diseases | ClinVar | | malaria | | ISO | TNF (Homo sapiens) | 8554872 | ClinVar Annotator: match by term: Malaria more ... | ClinVar | PMID:10369255 more ... | megacolon | | ISO | TNF (Homo sapiens) | 8554872 | ClinVar Annotator: match by term: Megacolon | ClinVar | PMID:21681106 | migraine | | ISO | TNF (Homo sapiens) | 8554872 | ClinVar Annotator: match by term: Migraine with or without aura more ... | ClinVar | PMID:25741868 | proteasome-associated autoinflammatory syndrome 1 | | ISO | TNF (Homo sapiens) | 8554872 | ClinVar Annotator: match by term: Proteasome-associated autoinflammatory syndrome 1 | ClinVar | PMID:28492532 | psoriatic arthritis | | ISO | TNF (Homo sapiens) | 8554872 | ClinVar Annotator: match by term: Psoriatic arthritis and susceptibility to | ClinVar | PMID:10450718 more ... | systemic lupus erythematosus | | ISO | TNF (Homo sapiens) | 8554872 | ClinVar Annotator: match by term: Systemic lupus erythematosus and susceptibility to | ClinVar | PMID:10450718 more ... | |
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PMID:7948427 | PMID:10331940 | PMID:11730929 | PMID:16022989 | PMID:17573384 | PMID:18343681 | PMID:19254251 | PMID:19261619 | PMID:19578946 | PMID:19605916 | PMID:21212278 | PMID:22154216 |
PMID:22300704 | PMID:22301074 | PMID:23978557 | PMID:24042337 | PMID:25312048 | PMID:26646413 | PMID:26692319 | PMID:26824356 | PMID:30032202 |
TNF (Canis lupus familiaris - dog) |
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TNF (Homo sapiens - human) |
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Tnf (Mus musculus - house mouse) |
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Tnf (Rattus norvegicus - Norway rat) |
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Tnf (Chinchilla lanigera - long-tailed chinchilla) |
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TNF (Pan paniscus - bonobo/pygmy chimpanzee) |
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Tnf (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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TNF (Sus scrofa - pig) |
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TNF (Chlorocebus sabaeus - green monkey) |
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Tnf (Heterocephalus glaber - naked mole-rat) |
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Variants in TNF
33 total Variants |
alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | reproductive system | respiratory system | adipose tissue | |
High | ||||||||||||
Medium | 3 | |||||||||||
Low | 4 | 10 | 6 | 3 | 6 | 6 | 1 | 6 | 2 | |||
Below cutoff | 1 | 5 | 12 | 5 | 11 | 8 | 4 | 4 |
RefSeq Transcripts | NM_001003244 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
GenBank Nucleotide | AAEX04000012 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
AB819627 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AB819628 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AB819629 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AF103743 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AF327899 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AF349537 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
AY423389 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
DQ923808 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
EU249361 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
JAAHUQ010000123 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
JAAQRD010000012 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
JAAUVH010000357 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
LN874472 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
REHQ01000012 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
S74068 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
X94932 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
Z70046 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
RefSeq Acc Id: | ENSCAFT00000000804 ⟹ ENSCAFP00000000739 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | ENSCAFT00000093235 ⟹ ENSCAFP00000065180 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | ENSCAFT00845018595 ⟹ ENSCAFP00845014504 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | ENSCAFT00845018639 ⟹ ENSCAFP00845014546 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | NM_001003244 ⟹ NP_001003244 | ||||||||||||||||||||||||||||
RefSeq Status: | PROVISIONAL | ||||||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||||||
Position: |
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Sequence: |
Protein RefSeqs | NP_001003244 | (Get FASTA) | NCBI Sequence Viewer |
GenBank Protein | AAB32391 | (Get FASTA) | NCBI Sequence Viewer |
AAD40571 | (Get FASTA) | NCBI Sequence Viewer | |
AAK54071 | (Get FASTA) | NCBI Sequence Viewer | |
AAL26919 | (Get FASTA) | NCBI Sequence Viewer | |
AAR27885 | (Get FASTA) | NCBI Sequence Viewer | |
ABJ51909 | (Get FASTA) | NCBI Sequence Viewer | |
ABX26051 | (Get FASTA) | NCBI Sequence Viewer | |
BAO03771 | (Get FASTA) | NCBI Sequence Viewer | |
BAO03772 | (Get FASTA) | NCBI Sequence Viewer | |
BAO03773 | (Get FASTA) | NCBI Sequence Viewer | |
CAA64403 | (Get FASTA) | NCBI Sequence Viewer | |
CAA93908 | (Get FASTA) | NCBI Sequence Viewer | |
CTQ86237 | (Get FASTA) | NCBI Sequence Viewer | |
Ensembl Protein | ENSCAFP00000000739.3 | ||
ENSCAFP00000065180.1 | |||
ENSCAFP00030008179.1 | |||
ENSCAFP00030008206.1 | |||
ENSCAFP00040015692.1 | |||
ENSCAFP00040015714.1 | |||
ENSCAFP00805020516 | |||
ENSCAFP00845014504 | |||
ENSCAFP00845014504.1 | |||
ENSCAFP00845014546.1 | |||
GenBank Protein | P51742 | (Get FASTA) | NCBI Sequence Viewer |
RefSeq Acc Id: | NP_001003244 ⟸ NM_001003244 |
- UniProtKB: | Q006K5 (UniProtKB/Swiss-Prot), Q28339 (UniProtKB/Swiss-Prot), P51742 (UniProtKB/Swiss-Prot), A9LMQ0 (UniProtKB/TrEMBL), A0A8I3N4X6 (UniProtKB/TrEMBL), A0A8C0L329 (UniProtKB/TrEMBL), A0A8C0M945 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | ENSCAFP00000000739 ⟸ ENSCAFT00000000804 |
RefSeq Acc Id: | ENSCAFP00000065180 ⟸ ENSCAFT00000093235 |
RefSeq Acc Id: | ENSCAFP00845014504 ⟸ ENSCAFT00845018595 |
RefSeq Acc Id: | ENSCAFP00845014546 ⟸ ENSCAFT00845018639 |
Database | Acc Id | Source(s) |
Ensembl Genes | ENSCAFG00000000517 | Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
ENSCAFG00030005072 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
ENSCAFG00040009744 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
ENSCAFG00805014361 | UniProtKB/Swiss-Prot | |
ENSCAFG00845010558 | Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Ensembl Transcript | ENSCAFT00000000804.5 | UniProtKB/Swiss-Prot |
ENSCAFT00000093235.2 | UniProtKB/TrEMBL | |
ENSCAFT00030009334.1 | UniProtKB/TrEMBL | |
ENSCAFT00030009369.1 | UniProtKB/Swiss-Prot | |
ENSCAFT00040018078.1 | UniProtKB/Swiss-Prot | |
ENSCAFT00040018102.1 | UniProtKB/TrEMBL | |
ENSCAFT00805026116 | UniProtKB/Swiss-Prot | |
ENSCAFT00845018595 | ENTREZGENE | |
ENSCAFT00845018595.1 | UniProtKB/Swiss-Prot | |
ENSCAFT00845018639.1 | UniProtKB/TrEMBL | |
Gene3D-CATH | 2.60.120.40 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
InterPro | TNF | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
TNF_alpha | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
TNF_CS | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
TNF_dom | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Tumour_necrosis_fac-like_dom | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
KEGG Report | cfa:403922 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
NCBI Gene | TNF | ENTREZGENE |
PANTHER | PTHR11471:SF23 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
TUMOR NECROSIS FACTOR FAMILY MEMBER | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Pfam | TNF | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
PRINTS | TNECROSISFCT | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
TNFALPHA | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
PROSITE | TNF_1 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
TNF_2 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
SMART | TNF | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
Superfamily-SCOP | SSF49842 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
UniProt | A0A8C0L329 | ENTREZGENE |
A0A8C0M945 | ENTREZGENE, UniProtKB/TrEMBL | |
A0A8I3N4X6 | ENTREZGENE, UniProtKB/TrEMBL | |
A9LMQ0 | ENTREZGENE, UniProtKB/TrEMBL | |
P51742 | ENTREZGENE | |
Q006K5 | ENTREZGENE | |
Q28339 | ENTREZGENE | |
TNFA_CANLF | UniProtKB/Swiss-Prot | |
UniProt Secondary | Q006K5 | UniProtKB/Swiss-Prot |
Q28339 | UniProtKB/Swiss-Prot | |
VGNC ID | VGNC:47647 | ENTREZGENE |