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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3876
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tnf
Name: tumor necrosis factor
Acc ID: CHEBI:135628
Term: cloricromen
Definition: null
Chemical ID: MESH:C025945
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tnfdecreases expressionEXP 6480464CTDcloricromen results in decreased expression of TNF proteinPMID:16572308
Tnfmultiple interactionsEXP 6480464CTDcloricromen inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; cloricromen inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; cloricromen inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; cloricromen inhibits the reaction [Streptozocin results in increased expression of TNF protein]PMID:11343695 PMID:15322736 PMID:19279317
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