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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3876
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tnf
Name: tumor necrosis factor
Acc ID: CHEBI:44485
Term: N-ethylmaleimide
Definition: A member of the class of maleimides that is the N-ethyl derivative of maleimide.
Chemical ID: MESH:D005033
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tnfmultiple interactionsISORGD:13441926480464CTDEthylmaleimide inhibits the reaction [TNF protein results in increased expression of SOD2 mRNA] Ethylmaleimide inhibits the reaction [TNF protein results in increased expression of SOD2 protein]

PMID:7476933
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