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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3876
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tnf
Name: tumor necrosis factor
Acc ID: CHEBI:174748
Term: C.I. Natural Red 20
Definition: null
Chemical ID: MESH:C016101
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tnfmultiple interactionsISOTnf (Mus musculus)6480464CTDshikonin inhibits the reaction [[Tobacco Smoke Pollution results in increased abundance of Particulate Matter] which results in increased expression of TNF protein]; shikonin inhibits the reaction [Antigen-Antibody Complex results in increased expression of TNF mRNA]; shikonin inhibits the reaction [Benzene results in increased expression of TNF mRNA]; shikonin inhibits the reaction [Calcimycin results in increased expression of TNF mRNA]PMID:25451590 PMID:35787437 PMID:36306860
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