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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3876
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tnf
Name: tumor necrosis factor
Acc ID: CHEBI:80230
Term: Potassium 2,6-dihydroxytriazinecarboxylate
Definition: An organic molecular entity that has formula C4H2KN3O4.
Chemical ID: MESH:C489337
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tnfmultiple interactionsEXP 6480464CTD[Inosine Monophosphate co-treated with potassium oxonate] inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; potassium oxonate inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]PMID:20868668
Tnfmultiple interactionsISORGD:114296480464CTD[Hypoxanthine co-treated with potassium oxonate] inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of TNF mRNA]PMID:33749747
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