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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3876
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tnf
Name: tumor necrosis factor
Acc ID: CHEBI:8984
Term: sodium dodecyl sulfate
Definition: An organic sodium salt that is the sodium salt of dodecyl hydrogen sulfate.
Chemical ID: MESH:D012967
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tnfaffects expressionISOTNF (Homo sapiens)6480464CTDSodium Dodecyl Sulfate affects the expression of TNF mRNAPMID:20385217
Tnfincreases expressionISOTNF (Homo sapiens)6480464CTDSodium Dodecyl Sulfate results in increased expression of TNF mRNAPMID:31734321 PMID:9856837
Tnfincreases secretionISOTNF (Homo sapiens)6480464CTDSodium Dodecyl Sulfate results in increased secretion of TNF proteinPMID:15679580
Tnfmultiple interactionsISOTNF (Homo sapiens)6480464CTDSodium Dodecyl Sulfate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of TNF protein]; TNF protein affects the reaction [Sodium Dodecyl Sulfate results in increased secretion of CCL20 protein]; TNF protein affects the reaction [Sodium Dodecyl Sulfate results in increased secretion of CXCL8 protein]PMID:15679580 PMID:36416909
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