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Pathways
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Gene: TNF (tumor necrosis factor) Sus scrofa
Analyze
Symbol: TNF
Name: tumor necrosis factor
Description: ENCODES a protein that exhibits identical protein binding (inferred); protease binding (inferred); transcription regulatory region DNA binding (inferred); INVOLVED IN positive regulation of endothelial cell apoptotic process; positive regulation of estradiol secretion; regulation of fat cell differentiation; PARTICIPATES IN allograft rejection pathway; Alzheimer's disease pathway; amyotrophic lateral sclerosis pathway; ASSOCIATED WITH acne (ortholog); acquired immunodeficiency syndrome (ortholog); Acute Coronary Syndrome (ortholog); FOUND IN external side of plasma membrane (inferred); integral component of plasma membrane (inferred); membrane raft (inferred); INTERACTS WITH (-)-epigallocatechin 3-gallate; 1,3-thiazolidine-2,4-dione; 2,3-dimethoxynaphthalene-1,4-dione
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: cachectin; TNF-a; TNF-alpha; TNFa; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor ligand superfamily member 2
Orthologs:
Homo sapiens (human) : TNF (tumor necrosis factor)  HGNC  Alliance
Mus musculus (house mouse) : Tnf (tumor necrosis factor)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tnf (tumor necrosis factor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tnf (tumor necrosis factor)
Pan paniscus (bonobo/pygmy chimpanzee) : TNF (tumor necrosis factor)
Canis lupus familiaris (dog) : TNF (tumor necrosis factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tnf (tumor necrosis factor)
Heterocephalus glaber (naked mole-rat) : Tnf (tumor necrosis factor)
more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl723,699,636 - 23,703,655 (+)Ensembl
Sscrofa11.1723,699,635 - 23,702,393 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2727,549,619 - 27,552,377 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap7p11-q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
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Additional Information

External Database Links
  
More on TNF
NCBI Gene
Ensembl Gene
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RGD Object Information
RGD ID: 14181661
Created: 2019-01-29
Species: Sus scrofa
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.