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GENE - TERM ANNOTATION REPORT

RGD ID: 14181661
Species: Sus scrofa
RGD Object: Gene
Symbol: TNF
Name: tumor necrosis factor
Acc ID: DOID:10763
Term: hypertension
Definition: An artery disease characterized by chronic elevated blood pressure in the arteries. (DO)
Definition Source(s): https://en.wikipedia.org/wiki/Hypertension "DO" "DO", https://www.ncbi.nlm.nih.gov/pubmed/24352797 "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
TNF ISOTNF (Homo sapiens)9068941RGD PMID:16202847 REF_RGD_ID:1580312
TNF ISOTnf (Rattus norvegicus)9068941RGD PMID:9590569 REF_RGD_ID:1357163
TNFamelioratesISOTnf (Rattus norvegicus)9068941RGDassociated with Cardiac FibrosisPMID:25715999 REF_RGD_ID:401794570
TNFtreatmentISOTnf (Rattus norvegicus)9068941RGD PMID:16415373 REF_RGD_ID:1580207
TNF ISOTNF (Homo sapiens)9068941CTDCTD Direct Evidence: marker/mechanismPMID:18605955 PMID:27292124 PMID:27659729 PMID:27847271 PMID:32147540
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