Tnf (tumor necrosis factor) - Rat Genome Database
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Gene: Tnf (tumor necrosis factor) Mus musculus
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Symbol: Tnf
Name: tumor necrosis factor
RGD ID: 11429
MGI Page MGI
Description: Exhibits cytokine activity; protease binding activity; and tumor necrosis factor receptor binding activity. Involved in several processes, including apoptotic signaling pathway; positive regulation of cell communication; and positive regulation of macromolecule metabolic process. Localizes to several cellular components, including external side of plasma membrane; phagocytic cup; and recycling endosome. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and lung. Used to study several diseases, including autoimmune disease (multiple); congestive heart failure; heart valve disease (multiple); idiopathic pulmonary fibrosis; and spondyloarthropathy. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); eye disease (multiple); lung disease (multiple); and skin disease (multiple). Orthologous to human TNF (tumor necrosis factor).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cachectin; DI; DIF; MGC151434; Tn; TNF alpha; TNF-; TNF-a; TNF-alpha; Tnfa; TNFalpha; Tnfs; Tnfsf1a; TNFSF2; Tnlg1f; tumor necrosis factor alpha; tumor necrosis factor ligand 1f; tumor necrosis factor ligand superfamily member 2; tumor necrosis factor-alpha
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391735,418,343 - 35,420,983 (-)NCBIGRCm39mm39
GRCm381735,199,367 - 35,202,007 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1735,199,381 - 35,202,007 (-)EnsemblGRCm38mm10GRCm38
MGSCv371735,336,335 - 35,338,941 (-)NCBIGRCm37mm9NCBIm37
MGSCv361734,807,442 - 34,810,048 (-)NCBImm8
Celera1738,296,090 - 38,298,699 (-)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1718.59NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model