Tnf (tumor necrosis factor) - Rat Genome Database

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Gene: Tnf (tumor necrosis factor) Mus musculus
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Symbol: Tnf
Name: tumor necrosis factor
RGD ID: 11429
MGI Page MGI
Description: Enables protease binding activity; receptor ligand activity; and tumor necrosis factor receptor binding activity. Involved in several processes, including cellular response to cytokine stimulus; macrophage activation; and positive regulation of cell communication. Acts upstream of or within several processes, including apoptotic signaling pathway; positive regulation of intracellular signal transduction; and regulation of gene expression. Located in several cellular components, including external side of plasma membrane; phagocytic cup; and recycling endosome. Is active in extracellular space. Is expressed in several structures, including brain; genitourinary system; gut; integumental system; and lung. Used to study aortic valve stenosis; heart valve disease; inflammatory bowel disease; rheumatoid arthritis; and spondyloarthropathy. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); eye disease (multiple); lung disease (multiple); and skin disease (multiple). Orthologous to human TNF (tumor necrosis factor).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: cachectin; DI; DIF; MGC151434; Tn; TNF alpha; TNF-; TNF-a; TNF-alpha; Tnfa; TNFalpha; Tnfs; Tnfsf1a; TNFSF2; Tnlg1f; tumor necrosis factor alpha; tumor necrosis factor ligand 1f; tumor necrosis factor ligand superfamily member 2; tumor necrosis factor-alpha
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391735,418,343 - 35,420,983 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1735,418,357 - 35,420,983 (-)EnsemblGRCm39 Ensembl
GRCm381735,199,367 - 35,202,007 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1735,199,381 - 35,202,007 (-)EnsemblGRCm38mm10GRCm38
MGSCv371735,336,335 - 35,338,941 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361734,807,442 - 34,810,048 (-)NCBIMGSCv36mm8
Celera1738,296,090 - 38,298,699 (-)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1718.59NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acne  (ISO)
acquired immunodeficiency syndrome  (ISO)
Acute Coronary Syndrome  (ISO)
Acute Experimental Pancreatitis  (ISO)
Acute Hepatitis  (IEP,ISO)
acute kidney failure  (IMP,ISO)
Acute Liver Failure  (ISO)
Acute Lung Injury  (ISO)
acute myocardial infarction  (ISO)
adenocarcinoma  (ISO)
adult respiratory distress syndrome  (ISO)
Aggressive Fibromatosis  (ISO)
Albuminuria  (ISO)
Alcoholic Fatty Liver  (ISO)
alcoholic hepatitis  (ISO)
alcoholic liver cirrhosis  (ISO)
Alcoholic Liver Diseases  (ISO)
allergic bronchopulmonary aspergillosis  (IEP)
allergic contact dermatitis  (ISO)
allergic disease  (ISO)
Alveolar Bone Loss  (ISO)
Alzheimer's disease  (ISO)
Amebic Liver Abscess  (ISO)
amyloidosis  (ISO)
amyotrophic lateral sclerosis  (IEP)
amyotrophic lateral sclerosis type 1  (ISO)
anemia  (ISO)
Animal Disease Models  (ISO)
anogenital venereal wart  (ISO)
Anorexia  (ISO)
anterior uveitis  (ISO)
anthracosis  (ISO)
anthrax disease  (IEP)
anti-basement membrane glomerulonephritis  (ISO)
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis  (ISO)
anxiety disorder  (ISO)
aortic valve stenosis  (IAGP)
aplastic anemia  (ISO)
Arsenic Poisoning  (ISO)
asbestosis  (ISO)
aspiration pneumonia  (ISO)
asthma  (IMP,ISO)
atherosclerosis  (IDA,IEP,IMP,ISO)
atopic dermatitis  (ISO)
atrial fibrillation  (ISO)
autistic disorder  (ISO)
autoimmune hepatitis  (ISO)
autoimmune thyroiditis  (IMP)
B-Cell Chronic Lymphocytic Leukemia  (ISO)
bacterial pneumonia  (IMP,ISO)
Behcet's disease  (ISO)
berylliosis  (ISO)
beta thalassemia  (ISO)
bilirubin metabolic disorder  (ISO)
brain edema  (ISO)
brain infarction  (ISO)
Brain Injuries  (ISO)
brain ischemia  (ISO)
breast adenocarcinoma  (ISO)
breast cancer  (ISO)
Breast Neoplasms  (ISO)
Bronchial Hyperreactivity  (ISO)
bronchiectasis  (ISO)
bronchopulmonary dysplasia  (ISO)
Burns  (ISO)
Cachexia  (ISO)
calcinosis  (ISO)
cardiac arrest  (ISO)
Cardiomegaly  (ISO)
cardiomyopathy  (ISO)
Cardiotoxicity  (ISO)
Cardiovascular Pregnancy Complications  (ISO)
Cardiovirus Infections  (ISO)
Cerebral Hemorrhage  (ISO)
cerebral infarction  (IEP,ISO)
cervical cancer  (ISO)
Chemical and Drug Induced Liver Injury  (IEP,IMP,ISO)
Chemically-Induced Disorders  (ISO)
chlamydia  (ISO)
cholestasis  (ISO)
cholesteatoma of middle ear  (ISO)
chorioamnionitis  (ISO)
Chronic Allograft Dysfunction  (ISO)
Chronic Hepatitis C  (ISO)
Chronic Intermittent Hypoxia  (ISO)
chronic obstructive pulmonary disease  (ISO)
cicatricial pemphigoid  (ISO)
cochlear disease  (ISO)
colitis  (ISO)
Colonic Neoplasms  (ISO)
Colorectal Neoplasms  (ISO)
congenital diaphragmatic hernia  (ISO)
congestive heart failure  (ISO)
Cor pulmonale  (ISO)
corneal ulcer  (ISO)
coronary artery disease  (ISO)
coronary restenosis  (ISO)
Coronavirus infectious disease  (IEP)
Cough  (ISO)
COVID-19  (ISO)
Coxsackievirus Infections  (ISO)
Crohn's disease  (ISO)
cryoglobulinemia  (ISO)
cutaneous leishmaniasis  (ISO)
cystic fibrosis  (ISO)
cystitis  (ISO)
Cytomegalovirus Infections  (IMP)
cytomegalovirus retinitis  (IEP,IMP)
degenerative disc disease  (ISO)
demyelinating disease  (IMP)
dermatitis  (ISO)
dermatitis herpetiformis  (ISO)
dermatomyositis  (ISO)
diabetic angiopathy  (ISO)
Diabetic Cardiomyopathies  (ISO)
Diabetic Nephropathies  (ISO)
diabetic neuropathy  (ISO)
diabetic retinopathy  (ISO)
Diaphragmatic Hernia  (ISO)
dilated cardiomyopathy  (ISO)
dilated cardiomyopathy 1H  (ISO)
disease by infectious agent  (ISO)
Disease Progression  (ISO)
disseminated intravascular coagulation  (ISO)
drug allergy  (ISO)
Drug Eruptions  (ISO)
Drug-Related Side Effects and Adverse Reactions  (ISO)
dry eye syndrome  (IEP)
Eales Disease  (ISO)
Edema  (ISO)
Emphysema  (IMP)
encephalitis  (ISO)
encephalomyelitis  (IMP)
end stage renal disease  (ISO)
endometriosis  (ISO)
endophthalmitis  (ISO)
Endotoxemia  (IEP,ISO)
epididymitis  (ISO)
epilepsy  (ISO)
erythema nodosum  (ISO)
Escherichia Coli Infections  (ISO)
esophagitis  (ISO)
essential hypertension  (ISO)
Experimental Arthritis  (ISO)
Experimental Autoimmune Encephalomyelitis  (ISO)
Experimental Autoimmune Neuritis  (ISO)
Experimental Colitis  (ISO)
Experimental Diabetes Mellitus  (ISO)
Experimental Liver Cirrhosis  (IEP,ISO)
Experimental Liver Neoplasms  (IEP,ISO)
Experimental Mammary Neoplasms  (IMP)
Experimental Neoplasms  (ISO)
Experimental Radiation Injuries  (ISO)
extrahepatic cholestasis  (ISO)
extrinsic allergic alveolitis  (IEP,ISO)
eye disease  (ISO)
Fanconi anemia  (ISO)
farmer's lung  (ISO)
Fever  (ISO)
Fibrosis  (ISO)
focal segmental glomerulosclerosis  (IEP)
Fungal Lung Diseases  (ISO)
gastric ulcer  (ISO)
gastritis  (ISO)
Gaucher's disease  (ISO)
genetic disease  (ISO)
glaucoma  (IDA,IEP,IMP,ISO)
glomerulonephritis  (ISO)
Graves ophthalmopathy  (ISO)
Graves' disease  (ISO)
Hearing Loss  (IEP)
Hearing Loss, Noise-Induced  (ISO)
Heart Injuries  (IEP)
heart valve disease  (IAGP)
Heat Stroke  (ISO)
hemochromatosis  (ISO)
hemolytic-uremic syndrome  (ISO)
Hemorrhagic Shock  (ISO)
hepatic encephalopathy  (ISO)
hepatitis A  (ISO)
hepatitis B  (ISO)
hepatocellular carcinoma  (IEP,ISO)
hepatopulmonary syndrome  (ISO)
hepatorenal syndrome  (ISO)
hereditary hemorrhagic telangiectasia  (ISO)
herpes simplex virus keratitis  (IEP,IMP)
herpes zoster  (ISO)
hidradenitis suppurativa  (ISO)
high grade glioma  (ISO)
High-Frequency Hearing Loss  (IMP)
HIV Wasting Syndrome  (ISO)
human immunodeficiency virus infectious disease  (ISO)
Human Influenza  (ISO)
Hyperalgesia  (IEP,IMP,ISO)
hypercalcemia  (ISO)
hyperhomocysteinemia  (ISO)
hyperinsulinism  (ISO)
Hyperoxia  (IMP)
hypertension  (ISO)
hypochromic microcytic anemia  (ISO)
hypoglycemia  (ISO)
Hypotension  (ISO)
Hypothermia  (ISO)
idiopathic pulmonary fibrosis  (ISO)
IgA glomerulonephritis  (ISO)
impotence  (ISO)
inclusion body myopathy with Paget disease of bone and frontotemporal dementia  (ISO)
Inflammation  (ISO)
inflammatory bowel disease  (IAGP,IMP,ISO)
Insulin Resistance  (ISO)
intermediate uveitis  (ISO)
interstitial cystitis  (IMP)
Intervertebral Disc Displacement  (ISO)
Intestinal Reperfusion Injury  (ISO)
intracranial aneurysm  (ISO)
Intracranial Hemorrhages  (ISO)
intrahepatic cholestasis of pregnancy  (ISO)
iron deficiency anemia  (ISO)
Kawasaki disease  (ISO)
keratoconjunctivitis sicca  (ISO)
kidney disease  (ISO)
Kidney Reperfusion Injury  (IEP,ISO)
labyrinthitis  (IEP)
leishmaniasis  (ISO)
leprosy  (ISO)
listeriosis  (ISO)
liver cirrhosis  (ISO)
liver disease  (ISO)
Liver Neoplasms  (ISO)
Liver Reperfusion Injury  (IEP,ISO)
localized scleroderma  (ISO)
low tension glaucoma  (ISO)
lung disease  (IEP,IMP,ISO)
Lung Injury  (ISO)
Lung Neoplasms  (ISO)
lung non-small cell carcinoma  (ISO)
Lung Reperfusion Injury  (IEP,ISO)
lupus nephritis  (ISO)
lymphopenia  (ISO)
malaria  (ISO)
Manganese Poisoning  (ISO)
megacolon  (ISO)
melanoma  (ISO)
Meningeal Tuberculosis  (IMP)
metabolic dysfunction-associated steatohepatitis  (IEP,ISO)
metabolic dysfunction-associated steatotic liver disease  (ISO)
Metabolic Syndrome  (ISO)
mevalonic aciduria  (ISO)
Micronuclei, Chromosome-Defective  (ISO)
middle cerebral artery infarction  (IEP,ISO)
Middle East respiratory syndrome  (IEP)
migraine  (ISO)
migraine without aura  (ISO)
mitochondrial myopathy  (ISO)
mixed connective tissue disease  (ISO)
mucocutaneous leishmaniasis  (ISO)
mucopolysaccharidosis VI  (ISO)
multiple myeloma  (ISO)
Multiple Organ Failure  (ISO)
multiple sclerosis  (ISO)
muscular atrophy  (ISO)
muscular dystrophy  (ISO)
Mycobacterium avium complex disease  (ISO)
Mycoplasma pneumoniae pneumonia  (ISO)
myelodysplastic syndrome  (ISO)
myocardial infarction  (ISO)
Myocardial Ischemia  (ISO)
Myocardial Reperfusion Injury  (ISO)
myocardial stunning  (ISO)
myocarditis  (ISO)
myositis  (ISO)
Nasal Polyps  (ISO)
Nausea  (ISO)
Necrosis  (ISO)
Neoplasm Invasiveness  (ISO)
Neoplasm Metastasis  (ISO)
Nerve Degeneration  (ISO)
nervous system disease  (ISO)
Neuralgia  (ISO)
neuroblastoma  (ISO)
Neurogenic Inflammation  (ISO)
neutropenia  (ISO)
obesity  (IDA,ISO)
obstructive sleep apnea  (ISO)
occupational asthma  (ISO)
open-angle glaucoma  (ISO)
oral squamous cell carcinoma  (ISO)
oral submucous fibrosis  (ISO)
Osteolysis  (ISO)
otitis media  (IEP,ISO)
Otitis Media with Effusion  (IEP)
ovarian cancer  (ISO)
Oxygen-Induced Retinopathy  (IEP,IMP)
Pain  (ISO)
Painful Neuropathy  (IEP,IMP,ISO)
pancreatic cancer  (ISO)
paracoccidioidomycosis  (ISO)
Parkinson's disease  (ISO)
Parkinsonism  (IDA,IEP)
Pediatric Crohn's Disease  (ISO)
Penetrating Wounds  (ISO)
peptic esophagitis  (ISO)
perinatal necrotizing enterocolitis  (ISO)
periodontitis  (ISO)
Peripheral Nerve Injuries  (ISO)
peritonitis  (ISO)
periventricular leukomalacia  (ISO)
Picornaviridae Infections  (IEP)
placenta disease  (ISO)
Plaque, Atherosclerotic  (IEP)
plasmacytoma  (IMP)
Plasmodium falciparum malaria  (ISO)
Pleural Effusion  (ISO)
pleurisy  (IMP,ISO)
Pneumococcal Meningitis  (ISO)
Pneumococcal Pneumonia  (IEP,IMP)
pneumonia  (ISO)
polymyositis  (ISO)
portal hypertension  (ISO)
Postmenopausal Osteoporosis  (ISO)
Postoperative Cognitive Dysfunction  (ISO)
pre-eclampsia  (ISO)
Pregnancy-Induced Hypertension  (ISO)
Premature Birth  (ISO)
primary biliary cholangitis  (ISO)
Primary Graft Dysfunction  (ISO)
primary open angle glaucoma  (ISO)
primary sclerosing cholangitis  (ISO)
prostate cancer  (ISO)
proteasome-associated autoinflammatory syndrome 1  (ISO)
Pseudomonas Infections  (IDA,IEP,ISO)
psoriasis  (ISO)
psoriatic arthritis  (ISO)
pulmonary edema  (ISO)
pulmonary emphysema  (ISO)
pulmonary fibrosis  (IEP,IMP,ISO)
pulmonary hypertension  (IMP,ISO)
pulmonary sarcoidosis  (ISO)
pulmonary tuberculosis  (IEP,ISO)
pustulosis of palm and sole  (ISO)
Radiation Pneumonitis  (ISO)
radiculopathy  (ISO)
Refractory Anemia  (ISO)
relapsing polychondritis  (IEP)
renal cell carcinoma  (ISO)
renal hypertension  (ISO)
Reperfusion Injury  (ISO)
respiratory allergy  (ISO)
respiratory syncytial virus infectious disease  (IEP)
respiratory system disease  (ISO)
Respiratory Tract Infections  (ISO)
Retina Reperfusion Injury  (ISO)
retinal artery occlusion  (IEP)
retinal detachment  (IMP,ISO)
retinal disease  (ISO)
rheumatoid arthritis  (IAGP,ISO)
rhinitis  (ISO)
Rhinosinusitis  (IDA,ISO)
Right Ventricular Hypertrophy  (ISO)
root resorption  (ISO)
SAPHO syndrome  (ISO)
sarcoma  (ISO)
schizophrenia  (ISO)
sciatic neuropathy  (ISO)
scleritis  (ISO)
sensorineural hearing loss  (ISO)
Sepsis  (IDA,ISO)
septic arthritis  (ISO)
severe acute respiratory syndrome  (ISO)
Shock  (ISO)
sickle cell anemia  (ISO)
silicosis  (ISO)
Sjogren's syndrome  (ISO)
skin disease  (ISO)
small cell carcinoma  (ISO)
Soft Tissue Neoplasms  (ISO)
Spinal Cord Compression  (ISO)
Spinal Cord Injuries  (ISO)
Spine Osteoarthritis  (ISO)
spondyloarthropathy  (IAGP)
Stable Angina  (ISO)
status epilepticus  (ISO)
steatotic liver disease  (ISO)
Stevens-Johnson syndrome  (ISO)
Stomach Neoplasms  (ISO)
Streptococcal Infections  (ISO)
Streptococcus pneumonia  (IEP)
Stroke  (ISO)
Subarachnoid Hemorrhage  (ISO)
Sudden Hearing Loss  (ISO)
Systemic Candidiasis  (IEP)
systemic lupus erythematosus  (ISO)
Tachycardia  (ISO)
Temporomandibular Joint Disorders  (ISO)
thalassemia  (ISO)
thrombocytopenia  (ISO)
thrombosis  (ISO)
Thyroid Neoplasms  (ISO)
Tinnitus  (ISO)
Tongue Neoplasms  (IEP,ISO)
toxic shock syndrome  (ISO)
trachoma  (ISO)
transient cerebral ischemia  (ISO)
transitional cell carcinoma  (ISO)
Transplant Rejection  (ISO)
traumatic brain injury  (ISO)
trichinosis  (IMP)
trigeminal neuralgia  (ISO)
tuberculosis  (ISO)
type 1 diabetes mellitus  (ISO)
type 2 diabetes mellitus  (ISO)
typhoid fever  (ISO)
ulcerative colitis  (IEP,ISO)
ureteral obstruction  (ISO)
urinary bladder cancer  (ISO)
urticaria  (ISO)
uveitis  (ISO)
vascular dementia  (ISO)
vascular disease  (ISO)
Vascular System Injuries  (ISO)
Venous Thromboembolism  (ISO)
Ventricular Dysfunction  (ISO)
Viral Bronchiolitis  (ISO)
viral pneumonia  (IEP)
visceral leishmaniasis  (IMP,ISO)
visual epilepsy  (ISO)
vitiligo  (ISO)
Vogt-Koyanagi-Harada disease  (ISO)
Vulvar Vestibulitis  (ISO)
Weight Gain  (ISO)
Weill-Marchesani syndrome  (ISO)
Wilson disease  (ISO)
Wounds and Injuries  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-albicanol  (EXP)
(+)-artemisinin  (EXP)
(+)-catechin  (EXP,ISO)
(+)-epicatechin-3-O-gallate  (ISO)
(+)-isoborneol  (EXP)
(+)-pilocarpine  (EXP,ISO)
(+)-Pimaric acid  (ISO)
(+)-pinoresinol  (ISO)
(+)-sesamin  (EXP)
(+)-syringaresinol beta-D-glucoside  (EXP)
(+)-taxifolin  (EXP,ISO)
(+)-Tetrandrine  (EXP,ISO)
(-)-anisomycin  (ISO)
(-)-Arctigenin  (ISO)
(-)-citrinin  (EXP,ISO)
(-)-cotinine  (ISO)
(-)-demecolcine  (ISO)
(-)-epigallocatechin 3-gallate  (EXP,ISO)
(-)-hinokiresinol  (EXP)
(-)-matairesinol  (ISO)
(1->4)-beta-D-glucan  (ISO)
(20S)-ginsenoside Rg3  (EXP,ISO)
(20S)-ginsenoside Rh1  (EXP,ISO)
(2E,4E)-hexa-2,4-dienoic acid  (ISO)
(4-chloro-2-methylphenoxy)acetic acid  (ISO)
(4-oxo-3-\{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl\}-3,4-dihydrophthalazin-1-yl)acetic acid  (EXP)
(4Z,7Z,10Z,13Z,15E,19Z)-17-hydroxydocosahexaenoic acid  (EXP)
(5Z,8Z,11Z,13E)-15-HETE  (ISO)
(E)-roxithromycin  (ISO)
(E)-thiamethoxam  (ISO)
(R)-adrenaline  (ISO)
(R)-carnitine  (ISO)
(R)-linalyl acetate  (EXP)
(R)-lipoic acid  (EXP,ISO)
(R)-noradrenaline  (ISO)
(R,R)-tramadol  (ISO)
(R,R,R)-alpha-tocopherol  (EXP,ISO)
(S)-(-)-perillyl alcohol  (ISO)
(S)-AMPA  (ISO)
(S)-colchicine  (EXP,ISO)
(S)-naringenin  (EXP,ISO)
(S)-nicotine  (EXP,ISO)
(S)-ropivacaine  (ISO)
(Z)-ligustilide  (EXP)
1'-acetoxychavicol acetate  (ISO)
1,1'-azobis(N,N-dimethylformamide)  (ISO)
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (EXP,ISO)
1,1-bis(2-aminoethyl)-2-hydroxy-3-oxotriazane  (ISO)
1,1-dichloroethene  (EXP)
1,1-dimethyl-4-phenylpiperazinium iodide  (ISO)
1,2,3-Trichloropropane  (ISO)
1,2-dibromoethane  (ISO)
1,2-dichlorobenzene  (EXP)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP,ISO)
1,3,5-trinitro-1,3,5-triazinane  (ISO)
1,3,5-trinitrobenzene  (EXP)
1,3,7,9-tetramethyluric acid  (ISO)
1,3-benzothiazole-2-thiol  (ISO)
1,3-dichloropropan-2-ol  (EXP)
1,4-benzoquinone  (EXP)
1,4-dithiothreitol  (EXP,ISO)
1,4-naphthoquinone  (EXP,ISO)
1,4-phenylenediamine  (EXP,ISO)
1,7-dimethylxanthine  (EXP,ISO)
1,8-cineole  (ISO)
1-(5-isoquinolinesulfonyl)-2-methylpiperazine  (EXP,ISO)
1-[(2,3,4-trimethoxyphenyl)methyl]piperazine  (EXP,ISO)
1-[2-(3,4-dichlorophenyl)ethyl]-4-methylpiperazine  (EXP,ISO)
1-bromopropane  (EXP)
1-chloro-2,4,6-trinitrobenzene  (EXP)
1-chloro-2,4-dinitrobenzene  (EXP,ISO)
1-fluoro-2,4-dinitrobenzene  (EXP,ISO)
1-hydroxy-1-norresistomycin  (ISO)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (EXP,ISO)
1-naphthaleneacetic acid  (EXP)
1-naphthyl isothiocyanate  (EXP,ISO)
1-Naphthylacetylspermine  (ISO)
1-nitropyrene  (ISO)
1-O-palmitoyl-2-O-(5-oxovaleryl)-sn-glycero-3-phosphocholine  (ISO)
1-octadec-9-enoylglycero-3-phosphate  (EXP)
1-Phenyl-6,7-dihydroxy-isochroman  (ISO)
11-deoxycorticosterone  (ISO)
11-deoxyprostaglandin E1  (ISO)
14-Deoxy-11,12-didehydroandrographolide  (ISO)
15-acetyldeoxynivalenol  (EXP,ISO)
15-deoxy-Delta(12,14)-prostaglandin J2  (ISO)
15-oxo-ETE  (ISO)
16,16-dimethylprostaglandin E2  (ISO)
17-hydroxyjolkinolide B  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17alpha-hydroxyprogesterone  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
1H-pyrazole  (EXP)
2''-galloylhyperin  (EXP)
2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP,ISO)
2,2'-bipyridine  (ISO)
2,2,2-trichloroethanol  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,3-bis(4-hydroxyphenyl)propionitrile  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP,ISO)
2,4-D  (EXP,ISO)
2,4-dinitrobenzenesulfonic acid  (ISO)
2,5-dihydroxybenzoic acid  (EXP)
2,5-hexanedione  (ISO)
2,6-di-tert-butyl-4-methylphenol  (EXP,ISO)
2,6-dichloroindophenol  (ISO)
2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile  (EXP,ISO)
2-(4-chloro-2-methylphenoxy)propanoic acid  (ISO)
2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine  (ISO)
2-acetamidofluorene  (ISO)
2-acetyl-1-alkyl-sn-glycero-3-phosphocholine  (EXP,ISO)
2-amino-2-deoxy-D-galactopyranose  (EXP,ISO)
2-amino-2-deoxy-D-glucopyranose  (EXP,ISO)
2-amino-2-deoxy-D-glucopyranose 6-phosphate  (EXP)
2-aminopurine  (EXP)
2-arachidonoylglycerol  (EXP,ISO)
2-butan-2-yl-4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-1,2,4-triazol-3-one  (EXP)
2-chloroethanol  (EXP)
2-deoxy-D-glucose  (EXP,ISO)
2-Hydroxy-6-(8,11,14-pentadecatrienyl)benzoic acid  (ISO)
2-hydroxyethyl methacrylate  (EXP,ISO)
2-hydroxypropanoic acid  (ISO)
2-O-acetyl-1-O-octadecyl-sn-glycero-3-phosphocholine  (ISO)
2-tert-butylhydroquinone  (EXP,ISO)
2-trans,6-trans,10-trans-geranylgeranyl diphosphate  (EXP,ISO)
2-trans,6-trans-farnesyl diphosphate  (EXP)
22-Hydroxycholesterol  (ISO)
23-epi-26-deoxyactein  (EXP)
3',5'-cyclic AMP  (EXP,ISO)
3',5'-cyclic GMP  (ISO)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (ISO)
3'-O-(4-Benzoyl)benzoyl ATP  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP,ISO)
3,3',4,4'-tetrachlorobiphenyl  (EXP)
3,3',5'-triiodo-L-thyronine  (ISO)
3,3',5'-triiodothyronine  (ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP,ISO)
3,3',5-triiodo-L-thyronine  (ISO)
3,3'-diindolylmethane  (EXP,ISO)
3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-1-decanol  (EXP)
3,4-dihydroxybenzoic acid  (EXP,ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3,5-diethoxycarbonyl-1,4-dihydrocollidine  (EXP)
3-[3-(tert-butylsulfanyl)-1-(4-chlorobenzyl)-5-(propan-2-yl)-1H-indol-2-yl]-2,2-dimethylpropanoic acid  (ISO)
3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione  (ISO)
3-acetyldeoxynivalenol  (EXP)
3-chloropropane-1,2-diol  (EXP,ISO)
3-hydroxybutyric acid  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (EXP,ISO)
3-mercaptopropanoic acid  (EXP)
3-methyladenine  (EXP,ISO)
3-methylcatechol  (EXP)
3-methylcholanthrene  (EXP,ISO)
3-Nitrofluoranthene  (ISO)
3-nitropropanoic acid  (EXP,ISO)
3-phenylprop-2-enal  (EXP,ISO)
4'-epidoxorubicin  (EXP)
4'-hydroxydiclofenac  (ISO)
4'-Methoxychalcone  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (EXP)
4-[6-(diaminomethylideneamino)-1-oxohexoxy]benzoic acid ethyl ester  (ISO)
4-\{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino\}benzoic acid  (ISO)
4-\{[4-(dimethylamino)phenyl]diazenyl\}phenyl-beta-lactoside  (EXP)
4-aminobenzoic acid  (ISO)
4-hydroperoxycyclophosphamide  (EXP)
4-hydroxy-3-[4-(2-hydroxyphenyl)phenyl]-6-oxo-7H-thieno[2,3-b]pyridine-5-carbonitrile  (EXP)
4-hydroxy-TEMPO  (EXP,ISO)
4-hydroxynon-2-enal  (EXP)
4-hydroxyphenyl retinamide  (EXP,ISO)
4-methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylic acid methyl ester  (EXP)
4-methylcatechol  (EXP)
4-methylhistamine  (ISO)
4-nitrophenol  (EXP)
4-Nitropyrene  (EXP)
4-nitroquinoline N-oxide  (ISO)
4-nonylphenol  (ISO)
4-octylphenol  (ISO)
4-phenylbutyric acid  (EXP)
4-tert-butylphenol  (ISO)
5'-S-methyl-5'-thioadenosine  (EXP)
5,6,7-trimethoxyflavone  (EXP)
5-(2-chloroethyl)-4-methylthiazole  (EXP)
5-(2-methylpiperazine-1-sulfonyl)isoquinoline  (EXP,ISO)
5-aminoimidazole-4-carboxamide  (ISO)
5-aza-2'-deoxycytidine  (EXP,ISO)
5-azacytidine  (EXP,ISO)
5-benzyl-1-(2-hydroxyethoxymethyl)uracil  (EXP)
5-fluorouracil  (EXP,ISO)
5-Hydroxycapric acid  (EXP,ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP,ISO)
5-methoxypsoralen  (ISO)
5-Nitro-2-(3-phenylpropylamino)benzoic acid  (EXP)
6-(cyclohexylmethoxy)-5-nitrosopyrimidine-2,4-diamine  (EXP,ISO)
6-aminonicotinamide  (EXP)
6-bromoindirubin-3'-oxime  (ISO)
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide  (EXP,ISO)
6-oxoprostaglandin F1alpha  (ISO)
6-propyl-2-thiouracil  (ISO)
6alpha-methylprednisolone  (EXP,ISO)
7,12-dimethyltetraphene  (EXP,ISO)
7,8-diacetoxy-4-methylcoumarin  (ISO)
7,8-dihydroxycoumarin  (EXP,ISO)
7,9-dihydro-1H-purine-2,6,8(3H)-trione  (EXP,ISO)
7-ketocholesterol  (ISO)
8-Br-cAMP  (EXP,ISO)
8-bromo-3',5'-cyclic GMP  (EXP)
8-OH-DPAT  (ISO)
9-cis,11-trans-octadecadienoic acid  (EXP)
9-cis-retinoic acid  (EXP,ISO)
9-Methoxycamptothecin  (ISO)
[6]-Shogaol  (EXP)
[des-Arg(9)]-bradykinin  (EXP)
AACOCF3  (ISO)
abacavir  (ISO)
abamectin  (ISO)
acarbose  (EXP,ISO)
aceclofenac  (EXP)
acetaldehyde  (ISO)
acetate  (ISO)
acetate ester  (ISO)
acetic acid  (EXP,ISO)
acetic anhydride  (ISO)
acetone  (ISO)
acetylcholine  (EXP)
acetylsalicylic acid  (EXP,ISO)
acrolein  (ISO)
acrylamide  (EXP,ISO)
acrylic acid  (ISO)
acrylonitrile  (EXP,ISO)
acteoside  (ISO)
actinomycin D  (EXP,ISO)
acyclovir  (ISO)
adenine  (EXP,ISO)
adenosine  (EXP,ISO)
Adenosine, cyclic 3',5'-[hydrogen [p(s)]-phosphorothioate]  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (EXP,ISO)
Aflatoxin B2 alpha  (EXP)
Aflatoxin G1  (EXP,ISO)
agathisflavone  (ISO)
agmatine  (EXP,ISO)
agrimoniin  (ISO)
AH23848  (ISO)
AICA ribonucleotide  (EXP,ISO)
alachlor  (EXP)
albendazole  (ISO)
albuterol  (EXP,ISO)
alcohol  (EXP,ISO)
aldehydo-D-glucosamine  (EXP,ISO)
aldehydo-D-glucosamine 6-phosphate  (EXP)
aldehydo-D-glucose  (EXP,ISO)
aldosterone  (ISO)
alendronic acid  (EXP)
alfacalcidol  (ISO)
alginic acid  (ISO)
aliskiren  (ISO)
Alisol B  (EXP)
Alkannin  (EXP,ISO)
all-trans-retinoic acid  (EXP,ISO)
all-trans-retinol  (ISO)
allantoin  (ISO)
allethrin  (ISO)
allicin  (ISO)
allopurinol  (EXP,ISO)
alloxan  (EXP,ISO)
alloxanthine  (ISO)
allyl alcohol  (ISO)
allyl isothiocyanate  (EXP,ISO)
allyl methyl disulfide  (EXP)
Aloe emodin  (ISO)
Alpha-Boswellic acid  (ISO)
alpha-Chaconine  (EXP)
alpha-D-galactose  (EXP,ISO)
alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide  (ISO)
alpha-hexylcinnamaldehyde  (EXP,ISO)
alpha-linolenic acid  (ISO)
alpha-mangostin  (ISO)
alpha-methylhistamine  (EXP)
alpha-naphthoflavone  (EXP,ISO)
alpha-pinene  (ISO)
alpha-Solamarine  (EXP)
Alpinetin  (ISO)
alternariol  (EXP,ISO)
Altertoxin II  (ISO)
aluminium atom  (EXP,ISO)
aluminium hydroxide  (EXP)
aluminium oxide  (EXP,ISO)
aluminium(0)  (EXP,ISO)
alvocidib  (EXP)
AM-251  (EXP)
ambroxol  (ISO)
amiloride  (EXP,ISO)
aminoguanidine  (EXP,ISO)
amiodarone  (EXP,ISO)
amitrole  (EXP,ISO)
amlexanox  (EXP)
amlodipine  (ISO)
ammonia  (ISO)
ammonium chloride  (ISO)
ammonium hexachloroplatinate  (ISO)
ammonium sulfate  (ISO)
Ammothamnine  (EXP,ISO)
amobarbital  (ISO)
amosite asbestos  (ISO)
amphetamine  (ISO)
amphibole asbestos  (EXP,ISO)
amphotericin B  (ISO)
ampicillin  (EXP,ISO)
amrinone  (ISO)
anandamide  (EXP,ISO)
andrastin A  (EXP)
andrographolide  (ISO)
androst-4-ene-3,17-dione  (ISO)
Anemoside B4  (EXP,ISO)
anethole  (ISO)
Anetholtrithion  (ISO)
angiotensin II  (ISO)
Angoline  (EXP)
aniline  (ISO)
anthocyanin  (EXP,ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (EXP,ISO)
anthracene  (ISO)
anthracene-1,8,9-triol  (ISO)
antigen  (EXP)
antimycin A  (EXP,ISO)
antipyrine  (EXP)
antirheumatic drug  (ISO)
Apafant  (ISO)
apigenin  (EXP,ISO)
apocynin  (EXP,ISO)
arachidonic acid  (EXP,ISO)
arachidonyl-2'-chloroethylamide  (EXP)
Arctiin  (ISO)
aripiprazole  (ISO)
aristolochic acid A  (EXP,ISO)
aristolochic acids  (ISO)
arjunolic acid  (ISO)
Arkin (TN)  (ISO)
Aroclor 1254  (ISO)
arsane  (EXP,ISO)
arsenic acid  (EXP)
arsenic atom  (EXP,ISO)
arsenite(3-)  (EXP,ISO)
arsenous acid  (EXP,ISO)
artesunate  (ISO)
asarone  (EXP)
asbestos  (EXP,ISO)
asiatic acid  (EXP,ISO)
aspalathin  (ISO)
aspartame  (EXP)
asperentin  (EXP)
asperuloside  (EXP)
Asperulosidic acid  (EXP)
astaxanthin  (EXP)
astilbin  (EXP,ISO)
astragaloside IV  (EXP,ISO)
astressin 2B  (ISO)
atorvastatin calcium  (EXP,ISO)
ATP  (EXP,ISO)
atrazine  (EXP,ISO)
atropine  (EXP)
aucubin  (EXP)
auranofin  (EXP,ISO)
aurantio-obtusin  (EXP)
aureusidin  (EXP)
azadirachtin A  (EXP)
azathioprine  (EXP,ISO)
azetidine  (EXP)
aziridines  (EXP,ISO)
azithromycin  (EXP)
azoxystrobin  (EXP)
baclofen  (ISO)
bafilomycin A1  (EXP,ISO)
baicalein  (EXP,ISO)
baicalin  (EXP,ISO)
BAPTA  (EXP)
Bardoxolone methyl  (EXP,ISO)
barium chloride  (ISO)
barium(0)  (EXP)
bathocuproine disulfonic acid  (ISO)
batimastat  (ISO)
Bavachinin  (EXP,ISO)
BAY 60-6583  (EXP)
beclomethasone  (ISO)
Belnacasan  (ISO)
benazepril  (ISO)
benfotiamine  (EXP)
benomyl  (ISO)
bentonite  (ISO)
benzalkonium chloride  (EXP,ISO)
benzamide  (ISO)
benzbromarone  (ISO)
benzene  (EXP,ISO)
benzene-1,2,4-triol  (ISO)
benzo[a]pyrene  (EXP,ISO)
Benzo[a]pyrene-7,8-diol  (ISO)
Benzo[ghi]perylene  (ISO)
benzoic acid  (ISO)
benzylpenicillin  (EXP)
beraprost  (EXP)
berberine  (EXP,ISO)
Bergenin  (EXP,ISO)
beryllium atom  (ISO)
beryllium dihydride  (ISO)
beryllium sulfate  (EXP,ISO)
beryllium(0)  (ISO)
Besigomsin  (EXP)
beta-amyrin  (EXP,ISO)
beta-carotene  (EXP,ISO)
beta-D-glucan  (EXP)
beta-D-glucosamine  (EXP,ISO)
beta-D-glucosamine 6-sulfate  (ISO)
beta-eudesmol  (EXP)
beta-ionone  (EXP)
beta-lapachone  (ISO)
beta-naphthoflavone  (ISO)
betalain  (EXP)
betulin  (ISO)
betulinic acid  (ISO)
bezafibrate  (EXP,ISO)
bicalutamide  (ISO)
bifenthrin  (EXP,ISO)
bilirubin IXalpha  (EXP,ISO)
biliverdin  (EXP)
biochanin A  (ISO)
biotin  (ISO)
bis(2-chloroethyl) sulfide  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisdemethoxycurcumin  (ISO)
Bisibuthiamine  (ISO)
bisoprolol  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol A diglycidyl ether  (EXP,ISO)
Bisphenol A glycidylmethacrylate  (ISO)
bisphenol F  (EXP,ISO)
bleomycin A2  (EXP,ISO)
boldenone  (ISO)
Boldine  (EXP)
boric acid  (ISO)
boron atom  (ISO)
bortezomib  (EXP,ISO)
bosentan  (EXP)
Botulinum toxin type A  (EXP,ISO)
BQ 123  (EXP,ISO)
brefeldin A  (EXP)
Brevetoxin B  (ISO)
Brevianamide A  (EXP)
bromoacetate  (ISO)
bromocriptine  (EXP,ISO)
bromodichloromethane  (EXP)
brucine  (EXP,ISO)
bucladesine  (EXP,ISO)
budesonide  (EXP,ISO)
Budlein A  (ISO)
bufalin  (ISO)
buspirone  (ISO)
busulfan  (ISO)
butachlor  (EXP)
butanal  (ISO)
butane-2,3-dione  (EXP,ISO)
butein  (ISO)
butylated hydroxyanisole  (EXP,ISO)
Butylbenzyl phthalate  (EXP)
butyric acid  (EXP,ISO)
C.I. Natural Red 20  (EXP)
C60 fullerene  (EXP)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
cadmium sulfate  (EXP,ISO)
caffeine  (EXP,ISO)
calcidiol  (EXP,ISO)
Calcimycin  (EXP,ISO)
calciol  (EXP,ISO)
calcitriol  (EXP,ISO)
Calcium arsenate  (ISO)
calcium atom  (EXP,ISO)
calcium dichloride  (EXP,ISO)
Calcium propionate  (ISO)
calcium(0)  (EXP,ISO)
calycosin  (ISO)
camostat  (EXP,ISO)
candesartan  (ISO)
cannabidiol  (EXP,ISO)
Cannabidivarin  (EXP)
cannabigerol  (ISO)
capsaicin  (EXP,ISO)
capsazepine  (EXP,ISO)
captan  (ISO)
captopril  (ISO)
carbachol  (EXP,ISO)
carbamate ester  (ISO)
carbamazepine  (ISO)
Carbaprostacyclin  (EXP)
carbendazim  (ISO)
CARBENOXOLONE  (EXP)
carbidopa  (EXP,ISO)
carbon atom  (ISO)
carbon monoxide  (EXP,ISO)
carbon nanotube  (EXP,ISO)
carboplatin  (ISO)
Cardamonin  (EXP,ISO)
carfilzomib  (EXP)
carmustine  (EXP,ISO)
carnosic acid  (EXP)
carnosine  (EXP,ISO)
Carnosol  (EXP,ISO)
carrageenan  (EXP,ISO)
carteolol  (ISO)
carvacrol  (EXP,ISO)
carvedilol  (ISO)
carveol  (EXP)
Casuarictin  (ISO)
catalpol  (EXP,ISO)
catechol  (EXP)
CCCP  (EXP,ISO)
cefoxitin  (EXP)
ceftaroline  (ISO)
ceftriaxone  (ISO)
celastrol  (EXP,ISO)
celecoxib  (EXP,ISO)
Cellulose, microcrystalline  (ISO)
ceric oxide  (EXP,ISO)
cerium trichloride  (EXP)
cerivastatin  (ISO)
ceruletide  (EXP,ISO)
cetylpyridinium  (ISO)
CGS-21680  (ISO)
chaetoglobosin A  (EXP)
chaetomugilin D  (EXP)
chalcone  (EXP)
chalcones  (EXP,ISO)
charcoal  (ISO)
Chebulagic acid  (ISO)
chelerythrine  (EXP)
chetomin  (ISO)
chitosan  (ISO)
chlorendic acid  (ISO)
chlornitrofen  (ISO)
chlorobenzene  (ISO)
chloroethene  (EXP)
chlorogenic acid  (EXP,ISO)
chloroprene  (ISO)
chloroquine  (EXP,ISO)
chlorothalonil  (ISO)
chlorpromazine  (EXP,ISO)
chlorpyrifos  (EXP,ISO)
cholate  (ISO)
cholesterol  (EXP,ISO)
cholic acid  (EXP)
choline  (EXP,ISO)
chondroitin sulfate  (ISO)
chromium atom  (EXP,ISO)
chromium(3+) trichloride  (EXP,ISO)
chromium(6+)  (EXP,ISO)
chrysene  (ISO)
chrysin  (EXP,ISO)
cicaprost  (ISO)
cilostazol  (EXP,ISO)
cimetidine  (EXP,ISO)
Cinobufagin  (ISO)
ciprofibrate  (EXP)
ciprofloxacin  (EXP,ISO)
cirsilineol  (EXP)
Cirsimarin  (EXP,ISO)
cis-caffeic acid  (EXP,ISO)
cisplatin  (EXP,ISO)
citronellol  (ISO)
cladribine  (ISO)
clarithromycin  (ISO)
clenbuterol  (ISO)
clobetasol  (EXP)
clodronic acid  (EXP,ISO)
clofibrate  (EXP,ISO)
clomipramine  (ISO)
clonidine  (ISO)
clonidine (amino form)  (ISO)
clonidine (imino form)  (ISO)
clopidogrel  (EXP)
clorgyline  (ISO)
cloricromen  (ISO)
clothianidin  (ISO)
cloxacillin  (ISO)
clozapine  (ISO)
cobalt atom  (EXP,ISO)
cobalt dichloride  (EXP,ISO)
cocaine  (EXP,ISO)
coenzyme Q10  (EXP,ISO)
colforsin daropate hydrochloride  (EXP,ISO)
colistin  (ISO)
compound 48/80  (ISO)
coniferyl aldehyde  (ISO)
conjugated linoleic acid  (EXP,ISO)
copanlisib  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) chloride  (EXP,ISO)
copper(II) sulfate  (ISO)
cordycepin  (EXP,ISO)
corilagin  (EXP,ISO)
corticosterone  (EXP,ISO)
cortisol  (EXP,ISO)
cortisone  (EXP)
corynoline  (EXP)
costunolide  (EXP)
coumarin  (ISO)
coumarins  (EXP,ISO)
coumermycin A1  (EXP)
coumestrol  (EXP)
crocidolite asbestos  (EXP,ISO)
crocin-1  (ISO)
crotonaldehyde  (ISO)
Cryptotanshinone  (ISO)
CU-O LINKAGE  (ISO)
cucurbitacin B  (EXP)
cudratricusxanthone A  (EXP)
cumene hydroperoxide  (EXP)
Cuprizon  (EXP)
curcumin  (EXP,ISO)
Curcumol  (ISO)
cyanidin cation  (EXP)
cyanocob(III)alamin  (ISO)
cyclizine  (EXP)
cycloastragenol  (ISO)
cycloheximide  (EXP,ISO)
cyclophosphamide  (EXP,ISO)
cyclosporin A  (EXP,ISO)
cyfluthrin  (EXP,ISO)
cyhalothrin  (ISO)
cylindrospermopsin  (ISO)
cypermethrin  (EXP,ISO)
cytarabine  (ISO)
cytisine  (EXP)
cytochalasin D  (EXP,ISO)
D-glucose  (EXP,ISO)
D-mannitol  (EXP)
D-penicillamine  (EXP)
dabigatran  (ISO)
dabrafenib  (ISO)
dacarbazine  (EXP)
daidzein  (EXP)
danazol  (ISO)
dantrolene  (EXP,ISO)
dapagliflozin  (ISO)
dapoxetine  (ISO)
DAPT  (EXP,ISO)
daunorubicin  (ISO)
DDE  (EXP,ISO)
DDT  (EXP,ISO)
decabromodiphenyl ether  (EXP,ISO)
Decursin  (EXP)
deferiprone  (ISO)
deguelin  (EXP,ISO)
dehydrocostus lactone  (EXP)
dehydroepiandrosterone  (ISO)
delphinidin  (EXP)
Delta(9)-tetrahydrocannabinolic acid  (EXP)
delta-tocotrienol  (EXP)
delta8-THC  (ISO)
demeclocycline  (ISO)
demethoxycurcumin  (ISO)
deoxycholic acid  (EXP,ISO)
Deoxycorticosterone acetate  (EXP)
deoxynivalenol  (EXP,ISO)
desferrioxamine B  (EXP,ISO)
desflurane  (ISO)
desipramine  (ISO)
devazepide  (EXP)
dexamethasone  (EXP,ISO)
dexamethasone phosphate  (ISO)
dexmedetomidine  (EXP,ISO)
dextran sulfate  (EXP,ISO)
dextromethorphan  (EXP,ISO)
Di-n-hexyl phthalate  (ISO)
diallyl disulfide  (EXP)
Diallyl sulfide  (EXP,ISO)
diallyl trisulfide  (EXP,ISO)
diarsenic trioxide  (EXP,ISO)
diazepam  (EXP)
diazinon  (EXP,ISO)
diazoxide  (EXP,ISO)
diazoxon  (ISO)
dibenziodolium  (EXP,ISO)
dibutyl phthalate  (EXP,ISO)
dibutylstannane  (EXP)
dichlorine  (EXP)
dichloroacetic acid  (EXP,ISO)
dichloroacetyl chloride  (EXP,ISO)
dichloromethane  (EXP)
dichlorvos  (ISO)
dichromic acid  (ISO)
dichromium trioxide  (ISO)
diclofenac  (EXP,ISO)
dicoumarol  (ISO)
Didecyldimethylammonium  (ISO)
dieckol  (EXP,ISO)
dieldrin  (ISO)
dienogest  (ISO)
diethyl dithiophosphate  (ISO)
diethyl maleate  (EXP,ISO)
diethyl phthalate  (ISO)
diethyldithiocarbamic acid  (EXP)
diethylstilbestrol  (EXP,ISO)
diflunisal  (ISO)
dihydroartemisinin  (ISO)
Dihydrotanshinone I  (EXP)
dihydroxyacetone  (ISO)
diiodine  (EXP)
diisononyl phthalate  (EXP)
diisopropyl fluorophosphate  (EXP,ISO)
Dimaprit  (EXP,ISO)
dimemorfan  (EXP)
dimethoate  (EXP)
dimethyl fumarate  (EXP,ISO)
dimethyl sulfoxide  (EXP,ISO)
dimethylarsinic acid  (EXP,ISO)
dimethylarsinous acid  (ISO)
diminazene diaceturate  (ISO)
Diosbulbin B  (EXP)
dioscin  (EXP,ISO)
diosgenin  (ISO)
diosmetin  (EXP)
diosmin  (ISO)
dioxygen  (EXP,ISO)
diprotium oxide  (ISO)
dipyridamole  (EXP)
diquat  (ISO)
disodium cromoglycate  (EXP)
disodium selenite  (EXP,ISO)
disulfiram  (EXP,ISO)
dithianon  (ISO)
diuron  (ISO)
divanadium pentaoxide  (ISO)
dobutamine  (ISO)
docebenone  (EXP)
dodecane  (ISO)
donepezil hydrochloride  (EXP,ISO)
dopamine  (EXP,ISO)
dopaminechrome (enol form)  (ISO)
doramapimod  (ISO)
dorsomorphin  (EXP,ISO)
doxepin  (ISO)
doxifluridine  (EXP,ISO)
doxorubicin  (EXP,ISO)
doxycycline  (ISO)
dydrogesterone  (ISO)
ebselen  (ISO)
EC 3.1.1.4 (phospholipase A2) inhibitor  (ISO)
edaravone  (EXP,ISO)
efavirenz  (ISO)
elemental boron  (ISO)
elemental carbon  (ISO)
elemental selenium  (EXP,ISO)
ellagic acid  (ISO)
emamectin benzoate  (ISO)
embelin  (ISO)
emodin  (EXP,ISO)
enalapril  (EXP,ISO)
enalaprilat dihydrate  (EXP)
endosulfan  (EXP,ISO)
enflurane  (ISO)
enilconazole  (EXP)
Enterolactone  (ISO)
epalrestat  (EXP)
Epimedin B  (EXP)
eplerenone  (ISO)
erdosteine  (EXP,ISO)
ergothioneine  (ISO)
eriodictyol  (EXP)
erythromycin A  (EXP,ISO)
erythrosin B  (ISO)
esculetin  (EXP)
estragole  (EXP)
estriol  (EXP,ISO)
estrone  (ISO)
etacrynic acid  (ISO)
ethanol  (EXP,ISO)
ethidium  (EXP)
ethion  (EXP)
ethionamide  (ISO)
ethyl methanesulfonate  (ISO)
Ethyl pyruvate  (EXP)
ethylene glycol  (ISO)
ethylene glycol bis(2-aminoethyl)tetraacetic acid  (EXP)
ethylenediaminetetraacetic acid  (ISO)
ethylmalonic acid  (ISO)
ethylmercuric chloride  (ISO)
eticlopride(1+)  (ISO)
etidronic acid  (ISO)
etoposide  (EXP,ISO)
eugenol  (EXP,ISO)
eumelanin  (EXP)
eupatilin  (EXP)
everolimus  (ISO)
Evodiamine  (ISO)
excitatory amino acid agonist  (ISO)
ezetimibe  (ISO)
famotidine  (EXP,ISO)
Fargesin  (EXP)
farnesol  (EXP,ISO)
farnesyl diphosphate  (EXP)
farrerol  (ISO)
fasudil  (EXP,ISO)
febuxostat  (ISO)
felodipine  (EXP)
fenamic acid  (EXP)
fenbendazole  (ISO)
fenitrothion  (ISO)
fenofibrate  (EXP,ISO)
fenoprofen  (EXP)
fentin chloride  (ISO)
fentin hydroxide  (EXP)
fenvalerate  (ISO)
ferric ammonium citrate  (EXP)
ferric oxide  (EXP,ISO)
ferroheme b  (EXP,ISO)
ferrosoferric oxide  (ISO)
ferrostatin-1  (ISO)
ferruginol  (ISO)
ferulic acid  (EXP)
Fexaramine  (EXP)
Fexofenadine hydrochloride  (ISO)
Fidarestat  (EXP)
finasteride  (ISO)
fingolimod hydrochloride  (EXP)
fipronil  (ISO)
fisetin  (EXP,ISO)
Flavokawain A  (EXP)
flavones  (EXP)
flavonoids  (EXP,ISO)
flavonols  (EXP)
flucloxacillin  (EXP,ISO)
flufenamic acid  (ISO)
flumequine  (EXP)
flunisolide  (ISO)
fluoranthene  (ISO)
fluorene  (ISO)
fluorometholone  (ISO)
fluoxetine  (EXP,ISO)
flurbiprofen  (EXP,ISO)
flutamide  (ISO)
fluticasone  (ISO)
folic acid  (EXP,ISO)
fomepizole  (ISO)
formaldehyde  (EXP,ISO)
formic acid  (EXP)
formoterol fumarate  (EXP,ISO)
Forsythiaside  (EXP)
fosinopril  (EXP)
fragrance  (ISO)
fraxetin  (ISO)
Fraxinellone  (EXP)
fructosamine  (ISO)
fructose  (EXP,ISO)
fucoxanthin  (EXP)
fulvestrant  (EXP,ISO)
fumaric acid  (EXP)
fumigaclavine C  (EXP)
fumonisin B1  (EXP)
furan  (EXP,ISO)
furosemide  (ISO)
Fusarenone X  (EXP)
gabexate methanesulfonate  (ISO)
gadolinium trichloride  (EXP,ISO)
galactose  (EXP,ISO)
galangin  (ISO)
galanthamine  (ISO)
gallic acid  (EXP,ISO)
gallocatechin  (ISO)
gamma-aminobutyric acid  (ISO)
gamma-hexachlorocyclohexane  (EXP,ISO)
gamma-linolenic acid  (ISO)
gamma-tocopherol  (ISO)
ganciclovir  (ISO)
Ganoderic acid A  (EXP)
Garcinol  (ISO)
Gastrodin  (EXP,ISO)
gefitinib  (EXP,ISO)
geldanamycin  (EXP,ISO)
gemcitabine  (ISO)
gemfibrozil  (EXP,ISO)
Genipin  (EXP)
Geniposide  (EXP)
genistein  (EXP,ISO)
genkwanin  (ISO)
gentamycin  (EXP,ISO)
Gentiopicrin  (EXP)
Geraniin  (EXP)
geraniol  (EXP,ISO)
geranylgeraniol  (ISO)
ghrelin  (EXP)
Gingerenone A  (EXP,ISO)
gingerol  (EXP,ISO)
Ginkgolide A  (EXP)
ginkgolide B  (ISO)
Ginkgolide C  (ISO)
ginsenoside C-K  (EXP,ISO)
ginsenoside Rb1  (EXP)
ginsenoside Re  (EXP,ISO)
ginsenoside Rg1  (EXP,ISO)
glafenine  (ISO)
gliclazide  (ISO)
gliotoxin  (ISO)
glucagon  (EXP)
glucose  (EXP,ISO)
glutaraldehyde  (ISO)
glutathione  (EXP,ISO)
Glutathione ethyl ester  (EXP)
Gly-His-Lys  (ISO)
glyburide  (EXP,ISO)
glycerol  (ISO)
glycidol  (ISO)
glycine  (EXP)
glycine betaine  (EXP)
glycyrrhetinate  (EXP,ISO)
glycyrrhetinic acid  (EXP,ISO)
glycyrrhizinic acid  (EXP,ISO)
glyoxal  (ISO)
glyphosate  (EXP,ISO)
Goe 6976  (EXP,ISO)
gold atom  (EXP)
gold nanoparticle  (ISO)
gold(0)  (EXP)
gossypin  (ISO)
graphene oxide  (EXP)
graphite  (EXP,ISO)
griseofulvin  (ISO)
GSK690693  (ISO)
guanidines  (EXP)
guggulsterone  (EXP,ISO)
GW 1929  (ISO)
GW 4064  (EXP,ISO)
GW 501516  (EXP,ISO)
GW 6471  (ISO)
gypenoside LXXV  (EXP)
haloperidol  (EXP,ISO)
halothane  (EXP,ISO)
Harpagide  (EXP)
helenalin  (EXP)
heme b  (EXP,ISO)
hemin  (EXP,ISO)
heparin  (ISO)
herbicide  (EXP,ISO)
herbimycin  (ISO)
heroin  (ISO)
hesperetin  (EXP,ISO)
hesperidin  (EXP,ISO)
hexadecanoic acid  (EXP,ISO)
hexaflumuron  (ISO)
hexanal  (ISO)
high-density lipoprotein cholesterol  (ISO)
hinokiflavone  (EXP)
histamine  (EXP,ISO)
homocysteine  (ISO)
homoeriodictyol  (EXP)
Honokiol  (EXP,ISO)
HU-308  (EXP,ISO)
huperzine A  (ISO)
hyaluronic acid  (EXP,ISO)
hydralazine  (ISO)
hydrocortisone succinate  (ISO)
hydrogen chloride  (EXP,ISO)
hydrogen peroxide  (EXP,ISO)
hydrogen sulfide  (EXP)
hydroquinone  (EXP,ISO)
hydroquinone O-beta-D-glucopyranoside  (ISO)
hydroxamic acid  (EXP,ISO)
hydroxychloroquine  (EXP,ISO)
hydroxycitronellal  (ISO)
hydroxysafflor yellow A  (EXP,ISO)
hydroxytyrosol  (EXP,ISO)
hydroxyurea  (ISO)
hypoxanthine  (EXP)
ibrutinib  (ISO)
Ibudilast  (ISO)
ibuprofen  (EXP,ISO)
icariin  (EXP,ISO)
icatibant  (ISO)
ICI 118551  (ISO)
icosanoid  (ISO)
idelalisib  (ISO)
ifosfamide  (ISO)
Iguratimod  (ISO)
Ile(5)-angiotensin II  (ISO)
imidacloprid  (EXP,ISO)
Imipenem-cilastatin  (EXP)
imipramine  (EXP,ISO)
imiquimod  (EXP,ISO)
immunological adjuvant  (ISO)
IMP  (ISO)
indinavir  (ISO)
indirubin-3'-monoxime  (EXP)
indole-3-acetic acid  (EXP)
indole-3-methanol  (EXP,ISO)
indoline  (ISO)
indometacin  (EXP,ISO)
indoprofen  (ISO)
insulin  (ISO)
insulin (human)  (ISO)
iohexol  (EXP,ISO)
ionomycin  (EXP,ISO)
iprodione  (EXP)
irbesartan  (EXP,ISO)
irigenin  (ISO)
irinotecan  (EXP,ISO)
iron atom  (EXP,ISO)
iron dextran  (EXP,ISO)
iron trichloride  (EXP,ISO)
iron(0)  (EXP,ISO)
iron(2+) sulfate (anhydrous)  (EXP,ISO)
iron(III) citrate  (ISO)
iron(III) nitrilotriacetate  (EXP,ISO)
isatin  (ISO)
isoamylol  (EXP)
isocyanates  (ISO)
isoeugenol  (EXP,ISO)
isoflavones  (ISO)
isoflurane  (EXP,ISO)
isoliquiritigenin  (EXP,ISO)
isoniazide  (ISO)
isoorientin  (ISO)
isoprenaline  (EXP,ISO)
isorhamnetin  (EXP,ISO)
isoscutellarein  (EXP)
isothiocyanate  (EXP)
isotretinoin  (ISO)
isovitexin  (EXP,ISO)
itraconazole  (EXP)
ivermectin  (EXP,ISO)
jaspamide  (ISO)
JTE-013  (ISO)
juglone  (ISO)
kaempferol  (EXP,ISO)
kaempferol 3-O-beta-D-glucoside  (EXP)
kahweol  (ISO)
kainic acid  (EXP,ISO)
kenpaullone  (ISO)
ketamine  (EXP,ISO)
ketoconazole  (EXP,ISO)
ketoprofen  (EXP)
ketotifen  (ISO)
KN-93  (EXP)
kojic acid  (ISO)
KT 5720  (ISO)
KT 5823  (EXP)
Kukoamine B  (EXP)
kuwanone G  (EXP)
kynurenic acid  (EXP)
L-1,4-dithiothreitol  (EXP,ISO)
L-365260  (EXP)
L-arginine  (EXP,ISO)
L-ascorbic acid  (EXP,ISO)
L-cysteine  (ISO)
L-ethionine  (EXP)
L-gamma-glutamyl-L-cysteine  (EXP)
L-glutamic acid  (EXP)
L-methionine  (EXP,ISO)
L-mimosine  (EXP,ISO)
L-proline betaine  (ISO)
lactacystin  (EXP,ISO)
lactulose  (ISO)
lamivudine  (ISO)
lansoprazole  (EXP,ISO)
latrunculin B  (ISO)
lead diacetate  (EXP,ISO)
lead nitrate  (EXP,ISO)
lead(0)  (EXP,ISO)
lead(II) chloride  (EXP,ISO)
leflunomide  (EXP)
lenalidomide  (EXP,ISO)
lentinan  (EXP)
Leonurine  (EXP,ISO)
letrozole  (ISO)
leukotriene D4  (ISO)
leuprolide  (ISO)
levamisole  (ISO)
levetiracetam  (ISO)
levofloxacin  (EXP,ISO)
levonorgestrel  (ISO)
Licarin A  (ISO)
Licochalcone A  (ISO)
Licochalcone B  (EXP)
lidocaine  (EXP,ISO)
lignan  (EXP)
lignin  (EXP)
limonene  (EXP,ISO)
limonin  (EXP)
linagliptin  (EXP,ISO)
linalool  (EXP)
linalyl acetate  (EXP)
linoleic acid  (ISO)
linsidomine  (EXP)
linuron  (EXP,ISO)
lipid As  (EXP)
lipoic acid  (EXP,ISO)
lipophosphoglycan  (ISO)
lipopolysaccharide  (EXP,ISO)
lipoteichoic acid  (EXP,ISO)
lipoxin A4  (EXP,ISO)
liquiritin  (EXP)
liraglutide  (ISO)
lithium atom  (EXP,ISO)
lithium carbonate  (EXP)
lithium chloride  (EXP,ISO)
lithium hydride  (EXP,ISO)
lithocholic acid  (EXP,ISO)
LLY-507  (EXP)
loganin  (EXP,ISO)
lonafarnib  (EXP,ISO)
lopinavir  (ISO)
lorcaserin  (EXP)
losartan  (EXP,ISO)
lovastatin  (EXP,ISO)
Lucidone  (ISO)
lumiracoxib  (EXP)
lupeol  (ISO)
luteolin  (EXP,ISO)
Luteolin 7-methyl ether  (ISO)
luteolin 7-O-beta-D-glucoside  (EXP)
luzindole  (ISO)
LY294002  (EXP,ISO)
lycopene  (EXP,ISO)
lycorine  (EXP)
m-xylene  (ISO)
Macrosphelide B  (EXP)
madecassoside  (ISO)
magnesium atom  (ISO)
Magnolol  (EXP)
malathion  (ISO)
maleic acid  (ISO)
malonaldehyde  (ISO)
malvidin 3-O-beta-D-glucoside  (EXP,ISO)
mancozeb  (EXP,ISO)
maneb  (EXP,ISO)
manganese atom  (EXP,ISO)
manganese(0)  (EXP,ISO)
manganese(II) chloride  (EXP,ISO)
manganese(II) sulfate  (EXP)
mangiferin  (EXP,ISO)
manoalide  (ISO)
manumycin A  (EXP,ISO)
masitinib  (ISO)
masoprocol  (EXP,ISO)
MC1568  (EXP)
mebendazole  (ISO)
Mecamylamine  (ISO)
mechlorethamine  (EXP,ISO)
meclofenamic acid  (ISO)
mecoprop  (ISO)
medroxyprogesterone acetate  (ISO)
MeIQx  (EXP)
melatonin  (EXP,ISO)
melittin  (EXP,ISO)
meloxicam  (EXP)
melphalan  (ISO)
memantine  (EXP,ISO)
menadione  (EXP,ISO)
mephedrone  (ISO)
mercaptoethanol  (ISO)
mercury atom  (EXP,ISO)
mercury dichloride  (EXP,ISO)
mercury(0)  (EXP,ISO)
mesalamine  (EXP,ISO)
metam  (EXP)
metamizole sodium  (ISO)
metformin  (EXP,ISO)
methacholine chloride  (EXP)
methadone  (ISO)
methamphetamine  (EXP,ISO)
methanol  (EXP,ISO)
methimazole  (ISO)
methotrexate  (EXP,ISO)
methoxsalen  (ISO)
methoxychlor  (EXP)
methyl 3,4,5-trihydroxybenzoate  (EXP)
methyl beta-cyclodextrin  (ISO)
methyl L-leucinate  (ISO)
methyl methacrylate  (ISO)
Methyl palmitate  (EXP)
methyl salicylate  (ISO)
methylene blue  (ISO)
methylglyoxal  (EXP,ISO)
methylisothiazolinone  (ISO)
methyllycaconitine  (EXP,ISO)
methylmalonic acid  (ISO)
methylmercury chloride  (ISO)
methylphenidate  (EXP)
Methylthiouracil  (ISO)
Methysticin  (EXP)
metiram  (ISO)
metoclopramide  (EXP)
metoprolol  (ISO)
metronidazole  (EXP)
metyrapone  (EXP,ISO)
mevalonic acid  (EXP,ISO)
mevastatin  (ISO)
mexiletine  (ISO)
microcystin-LR  (EXP,ISO)
mifepristone  (EXP,ISO)
Miglitol  (ISO)
milrinone  (ISO)
minocycline  (EXP,ISO)
miquelianin  (ISO)
mirtazapine  (ISO)
misoprostol  (ISO)
mitogen  (ISO)
MK 571  (EXP)
MK-2206  (ISO)
mocetinostat  (EXP)
molybdenum trichloride  (EXP)
mometasone furoate  (ISO)
monascin  (ISO)
mono(2-ethylhexyl) phthalate  (EXP)
monobenzyl phthalate  (ISO)
Monobutylphthalate  (EXP)
monocrotaline  (EXP,ISO)
monocrotophos  (ISO)
monosodium L-glutamate  (EXP,ISO)
monotropein  (EXP)
montelukast  (EXP,ISO)
morin  (EXP,ISO)
morphine  (EXP,ISO)
Morroniside  (EXP,ISO)
moxifloxacin  (ISO)
muramyl dipeptide  (EXP,ISO)
mycophenolic acid  (EXP,ISO)
mycotoxin  (EXP)
Mycotrienin I  (ISO)
Mycotrienin II  (ISO)
myo-inositol hexakisphosphate  (ISO)
myricetin  (ISO)
myricitrin  (EXP)
myrtenol  (ISO)
Myrtucommulone A  (EXP)
myxothiazol  (ISO)
N(gamma)-nitro-L-arginine methyl ester  (ISO)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (EXP,ISO)
N,N-diethyl-m-toluamide  (ISO)
N,N-dimethylacetamide  (EXP,ISO)
N,O-dimethyltyramine  (ISO)
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide  (EXP,ISO)
N-[2-(diethylamino)ethyl]-2-methoxy-5-methylsulfonylbenzamide  (ISO)
N-[3,5-bis(trifluoromethyl)phenyl]-5-chloro-2-hydroxybenzamide  (ISO)
N-[3-(aminomethyl)benzyl]acetamidine  (ISO)
N-acetyl-beta-D-glucosamine  (ISO)
N-acetyl-D-glucosamine  (ISO)
N-acetyl-L-cysteine  (EXP,ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (EXP,ISO)
N-desethylamiodarone  (ISO)
N-ethyl-5'-carboxamidoadenosine  (ISO)
N-ethyl-N-nitrosourea  (EXP)
N-ethylmaleimide  (ISO)
N-formyl-L-methionyl-L-leucyl-L-phenylalanine  (ISO)
N-hexadecanoylsphingosine  (EXP,ISO)
N-methyl-4-phenylpyridinium  (EXP,ISO)
N-methyl-N-nitrosourea  (EXP,ISO)
N-methylnicotinate  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (EXP,ISO)
N-tosyl-L-phenylalanyl chloromethyl ketone  (EXP,ISO)
N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine  (ISO)
nafcillin  (ISO)
naloxone  (EXP,ISO)
naltrexone  (ISO)
nandrolone  (ISO)
Nandrolone decanoate  (ISO)
naphthalene  (EXP)
naproxen  (ISO)
Narciclasine  (EXP)
naringin  (EXP,ISO)
nefazodone  (ISO)
Neferine  (ISO)
nelfinavir  (EXP,ISO)
neoastilbin  (EXP,ISO)
neocuproine  (EXP,ISO)
neoechinulin A  (EXP)
neomycin  (EXP)
neosaxitoxin  (EXP)
neostigmine  (ISO)
nerolidol  (ISO)
nickel atom  (EXP,ISO)
nickel dichloride  (EXP,ISO)
nickel sulfate  (EXP,ISO)
niclosamide  (EXP,ISO)
nicorandil  (EXP,ISO)
nicotinamide  (EXP,ISO)
nicotine  (EXP,ISO)
nicotinic acid  (ISO)
nifedipine  (ISO)
nifuroxazide  (ISO)
nigericin  (EXP)
nilotinib  (EXP,ISO)
nimesulide  (EXP,ISO)
nimodipine  (EXP)
nitrates  (EXP)
nitric oxide  (EXP,ISO)
nitrites  (EXP,ISO)
nitrofen  (EXP,ISO)
nitroflurbiprofen  (EXP,ISO)
nitrofurazone  (ISO)
nitrogen dioxide  (ISO)
nitroglycerin  (ISO)
nitroprusside  (EXP,ISO)
nitrososulfamethoxazole  (ISO)
nobiletin  (ISO)
Nodularin  (ISO)
nonane  (ISO)
nonanoic acid  (EXP)
nonivamide  (ISO)
Nonylphenol  (EXP,ISO)
norlaudanosoline  (EXP)
nortriptyline  (ISO)
norwogonin  (EXP)
notoginsenoside R1  (EXP,ISO)
NS-398  (EXP,ISO)
NSC 23766  (EXP,ISO)
o-anisidine  (ISO)
obeticholic acid  (EXP,ISO)
ochratoxin A  (EXP,ISO)
octadecanoic acid  (EXP)
octan-1-ol  (ISO)
octreotide  (EXP,ISO)
okadaic acid  (EXP,ISO)
olanzapine  (EXP)
olaparib  (EXP)
oleanolic acid  (EXP,ISO)
oleic acid  (EXP,ISO)
oleuropein  (EXP,ISO)
oligopeptide  (EXP)
Olmesartan medoxomil  (ISO)
Olopatadine hydrochloride  (EXP)
omeprazole  (EXP,ISO)
omethoate  (ISO)
organoselenium compound  (EXP,ISO)
oridonin  (ISO)
orlistat  (ISO)
oroxylin A  (EXP,ISO)
oxaliplatin  (ISO)
oxidopamine  (EXP,ISO)
ozone  (EXP,ISO)
p-cresol  (ISO)
p-menth-4(8)-en-3-one  (ISO)
p-menthan-3-ol  (ISO)
p-tolualdehyde  (EXP)
paclitaxel  (EXP,ISO)
paeoniflorin  (EXP,ISO)
Paeonol  (EXP,ISO)
palmatine  (EXP)
Palmitic acid(d3)  (ISO)
palmitoyl ethanolamide  (ISO)
pamidronate  (EXP,ISO)
paracetamol  (EXP,ISO)
paraoxon  (EXP,ISO)
paraquat  (EXP,ISO)
parathion  (EXP,ISO)
parathion-methyl  (ISO)
paricalcitol  (EXP)
paroxetine  (ISO)
parthenolide  (ISO)
patchouli alcohol  (EXP,ISO)
paxilline  (ISO)
PCB138  (EXP)
pefloxacin  (EXP)
pelargonidin  (EXP,ISO)
penconazole  (EXP)
pendimethalin  (ISO)
pentachlorophenol  (ISO)
pentanal  (ISO)
pentetic acid  (ISO)
pentobarbital  (EXP,ISO)
Pentoxifylline  (EXP,ISO)
peptidoglycan  (EXP,ISO)
perfluorobutyric acid  (ISO)
perfluorodecanoic acid  (EXP)
perfluorohexanesulfonic acid  (EXP)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
perifosine  (ISO)
perillyl alcohol  (ISO)
perindopril  (EXP,ISO)
permethrin  (EXP,ISO)
peroxynitrous acid  (ISO)
pevonedistat  (EXP)
phenanthrene  (EXP,ISO)
phenanthridone  (EXP,ISO)
phencyclidine  (ISO)
phenethyl caffeate  (EXP,ISO)
phenethyl isothiocyanate  (EXP,ISO)
phenobarbital  (ISO)
phenol  (EXP,ISO)
phentolamine  (ISO)
phenylacetaldehyde  (ISO)
phenylarsine oxide  (EXP,ISO)
phenylbutazone  (EXP,ISO)
phenylephrine  (ISO)
phenylhydrazine  (EXP,ISO)
phenytoin  (ISO)
PhIP  (EXP,ISO)
phloretin  (EXP)
phorbol 13-acetate 12-myristate  (EXP,ISO)
phosalone  (ISO)
phosgene  (ISO)
phosmet  (ISO)
phosphatidic acid  (EXP,ISO)
phosphatidylcholine  (EXP,ISO)
phosphocholine  (ISO)
phosphorylcholine chloride  (ISO)
phoxim  (ISO)
phthalaldehyde  (EXP)
phthalazine  (ISO)
phthalic anhydride  (EXP,ISO)
phthalimide  (ISO)
physostigmine  (EXP)
phytoestrogen  (EXP)
Phytolaccoside E  (EXP)
phytosterols  (EXP)
piclamilast  (ISO)
picolinic acid  (ISO)
picropodophyllotoxin  (EXP)
pimecrolimus  (EXP,ISO)
pimobendan  (EXP,ISO)
Pinacidil  (EXP,ISO)
pinitol  (EXP,ISO)
pinostrobin  (ISO)
pioglitazone  (EXP,ISO)
Pioglitazone hydrochloride  (ISO)
piperacillin  (ISO)
piperine  (ISO)
Pipermethystine  (ISO)
pipoxolan  (EXP)
Pirarubicin  (ISO)
pirfenidone  (ISO)
pirinixic acid  (EXP,ISO)
piroxicam  (EXP,ISO)
pitavastatin  (EXP)
pitavastatin(1-)  (EXP)
platycodin D  (EXP,ISO)
plaunotol  (ISO)
pluronic P-123  (EXP)
Poloxamer  (EXP)
Polpunonic acid  (EXP)
poly(ethylene)  (EXP,ISO)
poly(I:C)  (EXP,ISO)
polymyxin B2  (EXP,ISO)
polyphosphates  (ISO)
Potassium 2,6-dihydroxytriazinecarboxylate  (EXP,ISO)
potassium atom  (EXP,ISO)
potassium bromate  (EXP)
potassium chloride  (ISO)
potassium chromate  (EXP)
potassium dichromate  (EXP,ISO)
PR-39  (EXP)
Praeruptorin A  (EXP)
pravastatin  (EXP)
prednisolone  (EXP,ISO)
prednisone  (ISO)
pregabalin  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
pristane  (ISO)
proanthocyanidin  (ISO)
probenecid  (EXP)
probucol  (ISO)
procaterol  (ISO)
procyanidin B1  (ISO)
procyanidin B2  (ISO)
procymidone  (EXP)
prodigiosin  (ISO)
progesterone  (EXP,ISO)
promethazine  (ISO)
propacetamol  (EXP)
propamocarb  (EXP)
propan-2-ol  (EXP,ISO)
propanil  (EXP,ISO)
propionic acid  (ISO)
propofol  (EXP)
propranolol  (ISO)
propylparaben  (ISO)
prostaglandin A2  (ISO)
prostaglandin D2  (ISO)
prostaglandin E1  (EXP,ISO)
prostaglandin E2  (EXP,ISO)
prostaglandin F2alpha  (ISO)
protein kinase inhibitor  (ISO)
protoporphyrin  (ISO)
prunetin  (EXP)
Ptaquiloside  (EXP)
pterostilbene  (EXP,ISO)
puerarin  (EXP,ISO)
Punicalagin  (ISO)
pyocyanine  (EXP)
pyrene  (ISO)
Pyridostigmine bromide  (EXP,ISO)
pyridoxamine  (ISO)
pyrrolidine dithiocarbamate  (EXP,ISO)
pyrvinium  (ISO)
quartz  (EXP,ISO)
quercetin  (EXP,ISO)
quercetin 3-O-beta-D-galactopyranoside  (EXP)
quercetin 3-O-beta-D-glucofuranoside  (ISO)
quercetin 3-O-beta-D-glucopyranoside  (ISO)
quercetin 3-sulfate  (ISO)
quercitrin  (ISO)
quinazolines  (ISO)
quinine  (EXP,ISO)
quinoline  (EXP,ISO)
quinolinic acid  (ISO)
Quinotrierixin  (ISO)
rac-1,2-dichloropropane  (ISO)
rac-lactic acid  (ISO)
raloxifene  (EXP,ISO)
ramipril  (ISO)
ranitidine  (ISO)
Ranitidine bismuth citrate  (ISO)
raspberry ketone  (EXP,ISO)
reactive oxygen species  (EXP,ISO)
rebaudioside A  (ISO)
remdesivir  (ISO)
reserpine  (ISO)
resiniferatoxin  (ISO)
resiquimod  (EXP,ISO)
resolvin D1  (EXP)
resolvin D2  (EXP)
resorcinol  (ISO)
resveratrol  (EXP,ISO)
Rhein  (EXP,ISO)
Rhynchophylline  (ISO)
ribavirin  (ISO)
riboflavin  (EXP,ISO)
riddelliine  (ISO)
rifampicin  (ISO)
rifaximin  (EXP)
Riluzole  (ISO)
rimexolone  (ISO)
rimonabant  (EXP,ISO)
ritonavir  (EXP,ISO)
rivaroxaban  (ISO)
rivastigmine  (ISO)
Ro 31-8220  (EXP)
rofecoxib  (ISO)
roflumilast  (ISO)
rolipram  (EXP,ISO)
ropinirole  (ISO)
Roridin A  (EXP)
rosmarinic acid  (ISO)
rosuvastatin calcium  (ISO)
rotenone  (EXP,ISO)
rucaparib  (EXP)
Ruscogenin  (EXP)
Rutecarpine  (ISO)
ruthenium red  (EXP)
rutin  (EXP,ISO)
ruxolitinib  (EXP,ISO)
ryanodine  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
S-adenosyl-L-methioninate  (EXP,ISO)
S-adenosyl-L-methionine  (EXP,ISO)
S-allylcysteine  (EXP,ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (EXP,ISO)
S-nitrosoglutathione  (ISO)
saccharin  (EXP)
salicylates  (ISO)
salicylic acid  (ISO)
Salidroside  (EXP,ISO)
Salmeterol xinafoate  (EXP,ISO)
salubrinal  (EXP)
Salvianolic acid A  (EXP,ISO)
salvianolic acid B  (EXP,ISO)
Sanggenon C  (ISO)
sanguinarine  (ISO)
saquinavir  (EXP,ISO)
sarin  (ISO)
saroglitazar  (ISO)
sarpogrelate  (EXP,ISO)
saxagliptin  (ISO)
SB 203580  (EXP,ISO)
SB 206553  (EXP)
SB 415286  (EXP)
scalaradial  (ISO)
sciadopitysin  (EXP)
scoparone  (EXP)
scopolamine  (EXP,ISO)
scopoletin  (ISO)
selenium atom  (EXP,ISO)
serotonin  (EXP,ISO)
serpentine asbestos  (EXP,ISO)
sertraline  (ISO)
Sesamol  (EXP,ISO)
sesquiterpene  (ISO)
sevoflurane  (EXP,ISO)
Shikonin  (EXP)
sildenafil citrate  (EXP)
silibinin  (ISO)
silicic acid  (EXP)
silicon atom  (ISO)
silicon carbide  (ISO)
silicon dioxide  (EXP,ISO)
silver atom  (EXP,ISO)
silver(0)  (EXP,ISO)
silychristin  (ISO)
simazine  (EXP,ISO)
simvastatin  (EXP,ISO)
sinapic acid  (EXP,ISO)
sincalide  (ISO)
sinigrin  (EXP)
Sinomenine  (EXP)
sirolimus  (EXP,ISO)
sirtinol  (EXP,ISO)
SM-164  (EXP,ISO)
sodium acetate trihydrate  (EXP)
sodium arsenate  (EXP,ISO)
sodium arsenite  (EXP,ISO)
sodium azide  (ISO)
sodium benzoate  (EXP,ISO)
sodium chloride  (EXP,ISO)
sodium cholate  (ISO)
sodium dichromate  (EXP,ISO)
sodium dodecyl sulfate  (ISO)
sodium fluoride  (EXP,ISO)
sodium hydrogencarbonate  (EXP)
sodium hydrogensulfite  (EXP)
sodium nitrite  (ISO)
Sodium oleate  (ISO)
sodium perchlorate  (ISO)
sodium propionate  (EXP)
Sodium salicylate  (EXP,ISO)
sodium silicate  (ISO)
sodium stibogluconate  (ISO)
solasodine  (ISO)
Soman  (EXP,ISO)
Sophocarpine  (EXP)
Sophoricoside  (EXP)
sorafenib  (EXP,ISO)
sorbinil  (EXP,ISO)
soyasaponin I  (EXP)
sphingosine 1-phosphate  (ISO)
spironolactone  (ISO)
splitomicin  (ISO)
squalene  (ISO)
SR 144528  (ISO)
stattic  (EXP)
staurosporine  (EXP)
stavudine  (ISO)
sterigmatocystin  (EXP)
stigmasterol  (EXP,ISO)
streptomycin  (ISO)
streptozocin  (EXP,ISO)
styrene  (EXP,ISO)
succimer  (EXP,ISO)
sucrose  (EXP)
sulfamethizole  (EXP)
sulfapyridine  (ISO)
sulfasalazine  (EXP,ISO)
sulforaphane  (EXP,ISO)
sulfoxaflor  (ISO)
sulfur dioxide  (ISO)
sulindac  (EXP,ISO)
sulindac sulfide  (ISO)
sulindac sulfone  (ISO)
Sulpyrine  (ISO)
sumatriptan  (ISO)
sunitinib  (ISO)
Sunset Yellow FCF  (EXP)
superoxide  (EXP,ISO)
Suplatast tosilate  (EXP)
suramin  (ISO)
surfactin  (ISO)
surfactin C  (ISO)
synephrine  (EXP)
syringic acid  (ISO)
syringin  (EXP)
T-2 toxin  (EXP,ISO)
tacrine  (EXP)
tacrolimus hydrate  (EXP,ISO)
tadalafil  (EXP,ISO)
Talc  (ISO)
tamibarotene  (ISO)
tamoxifen  (EXP,ISO)
tangeretin  (ISO)
tannic acid  (ISO)
Tanshinone I  (EXP,ISO)
tartrazine  (ISO)
taurine  (EXP,ISO)
taurochenodeoxycholic acid  (ISO)
taurocholic acid  (ISO)
tazobactam  (ISO)
tebuconazole  (ISO)
tectorigenin  (EXP)
telithromycin  (ISO)
telmisartan  (EXP,ISO)
temozolomide  (ISO)
tenofovir disoproxil fumarate  (ISO)
tephrosin  (ISO)
terameprocol  (EXP)
terbinafine  (ISO)
terbutaline  (EXP,ISO)
Terfenadine  (ISO)
teriflunomide  (ISO)
tert-butanol  (ISO)
tert-butyl hydroperoxide  (EXP,ISO)
testosterone  (ISO)
testosterone enanthate  (ISO)
Testosterone propionate  (EXP)
tetrachloro-1,4-benzoquinone  (EXP)
tetrachloroethene  (ISO)
tetrachlorohydroquinone  (EXP)
tetrachloromethane  (EXP,ISO)
tetracyclines  (EXP)
tetradecane  (ISO)
tetrahydrocurcumin  (ISO)
tetralin  (EXP)
tetramethylpyrazine  (EXP,ISO)
Tetramethylthiourea  (EXP,ISO)
tetraphene  (ISO)
tetrathiomolybdate(2-)  (EXP)
tetrodotoxin  (EXP)
thalidomide  (EXP,ISO)
thapsigargin  (EXP,ISO)
theophylline  (EXP,ISO)
thiamethoxam  (ISO)
thiamine(1+) chloride  (ISO)
thiazoles  (ISO)
thiazolidinediones  (EXP)
thiazolidines  (ISO)
thimerosal  (ISO)
thioacetamide  (EXP,ISO)
thiomalic acid  (EXP)
thiopental  (ISO)
thiram  (ISO)
thromboxane B2  (ISO)
thymol  (EXP,ISO)
thymol sulfate(1-)  (EXP,ISO)
thymoquinone  (ISO)
thyroxine  (EXP,ISO)
tigecycline  (ISO)
Timosaponin b ii  (EXP)
Tiopronin  (ISO)
tiotropium bromide  (ISO)
tipifarnib  (EXP)
Tiron  (ISO)
titanium atom  (EXP,ISO)
titanium dioxide  (EXP,ISO)
TMC-120A  (EXP)
tobramycin  (ISO)
tocopherol  (ISO)
tofacitinib  (EXP,ISO)
toluene  (EXP,ISO)
toluene 2,4-diisocyanate  (EXP,ISO)
Tomentosin  (ISO)
topotecan  (ISO)
tramadol  (ISO)
tranilast  (ISO)
trans-anethole  (ISO)
trans-caffeic acid  (EXP,ISO)
trans-chalcone  (EXP)
trans-cinnamic acid  (EXP)
trans-isoeugenol  (EXP,ISO)
trans-piceid  (ISO)
trans-rhaponticin  (ISO)
trans-urocanic acid  (EXP)
trelagliptin  (EXP)
triamcinolone acetonide  (ISO)
tribromoethanol  (ISO)
tributylstannane  (EXP,ISO)
tributyrin  (ISO)
trichloroacetic acid  (EXP,ISO)
trichloroethene  (EXP,ISO)
trichostatin A  (EXP)
triclocarban  (EXP)
triclosan  (EXP,ISO)
Trienomycin A  (ISO)
trierixin  (ISO)
trilobatin  (EXP)
trimellitic anhydride  (EXP)
trimethylarsine oxide  (EXP)
trimethyltin  (EXP,ISO)
Triptolide  (EXP,ISO)
triptonide  (EXP)
troglitazone  (EXP,ISO)
troleandomycin  (EXP)
tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate  (EXP)
tropisetron  (ISO)
trovafloxacin  (EXP,ISO)
Tryptanthrine  (ISO)
tungsten  (EXP,ISO)
Tungsten carbide  (ISO)
tunicamycin  (EXP)
Tylophorine  (ISO)
tyloxapol  (EXP)
tyrphostin AG 1478  (ISO)
U-73122  (EXP)
ubiquinones  (ISO)
umbelliferone  (ISO)
undecan-2-one  (EXP,ISO)
uranium atom  (EXP,ISO)
urethane  (ISO)
urocanic acid  (EXP)
ursodeoxycholic acid  (EXP,ISO)
ursolic acid  (EXP)
usnic acid  (ISO)
vadimezan  (EXP,ISO)
valdecoxib  (ISO)
valproic acid  (EXP,ISO)
valsartan  (EXP,ISO)
vanadium atom  (ISO)
vanadium(0)  (ISO)
vancomycin  (EXP)
vanillin  (EXP,ISO)
vanoxerine dihydrochloride  (EXP)
vemurafenib  (ISO)
venom  (ISO)
verapamil  (EXP,ISO)
verbascose  (ISO)
verteporfin  (EXP,ISO)
very-low-density lipoprotein triglyceride  (ISO)
vildagliptin  (EXP)
vinclozolin  (ISO)
vincristine  (EXP,ISO)
vinorelbine  (EXP)
Vinpocetine  (EXP,ISO)
vitamin D  (EXP,ISO)
vitamin E  (EXP,ISO)
vitamin K  (ISO)
vorinostat  (ISO)
VX-745  (ISO)
Walleminone  (EXP)
warfarin  (ISO)
water  (ISO)
wedelolactone  (EXP,ISO)
WIN 55212-2  (EXP,ISO)
withaferin A  (EXP,ISO)
wogonin  (EXP,ISO)
wortmannin  (EXP,ISO)
xanthohumol  (ISO)
xyloglucan  (EXP)
Y-27632  (EXP,ISO)
Yangonin  (EXP)
yohimbine  (ISO)
Z-Val-Phe-H  (EXP)
zafirlukast  (ISO)
zaragozic acid A  (EXP,ISO)
zearalenone  (EXP,ISO)
zerumbone  (EXP,ISO)
zidovudine  (ISO)
zileuton  (EXP,ISO)
zinc atom  (EXP,ISO)
zinc dichloride  (EXP,ISO)
zinc molecular entity  (ISO)
zinc oxide  (EXP,ISO)
zinc protoporphyrin  (EXP,ISO)
zinc pyrithione  (ISO)
zinc sulfate  (EXP,ISO)
zinc(0)  (EXP,ISO)
zineb  (EXP,ISO)
zingerone  (EXP,ISO)
ziram  (ISO)
zoledronic acid  (EXP,ISO)
zotarolimus  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
animal organ morphogenesis  (IMP)
antiviral innate immune response  (ISO)
apoptotic signaling pathway  (IDA)
calcium-mediated signaling  (ISO)
cellular extravasation  (IDA)
cellular response to amino acid stimulus  (IDA)
cellular response to amyloid-beta  (ISO)
cellular response to lipopolysaccharide  (IDA,IMP,ISO)
cellular response to molecule of bacterial origin  (ISO)
cellular response to nicotine  (ISO)
cellular response to retinoic acid  (ISO)
cellular response to toxic substance  (ISO)
cellular response to type II interferon  (IMP,ISO)
chronic inflammatory response to antigenic stimulus  (ISO)
circadian rhythm  (ISO)
cortical actin cytoskeleton organization  (ISO)
defense response  (IMP)
defense response to bacterium  (IDA)
defense response to Gram-positive bacterium  (IGI)
detection of mechanical stimulus involved in sensory perception of pain  (ISO)
embryonic digestive tract development  (ISO)
endothelial cell apoptotic process  (IDA)
epithelial cell proliferation involved in salivary gland morphogenesis  (IDA)
extracellular matrix organization  (IDA)
extrinsic apoptotic signaling pathway  (IGI,ISO)
extrinsic apoptotic signaling pathway via death domain receptors  (IBA,IGI,ISO)
glucose metabolic process  (IDA)
humoral immune response  (IMP)
immune response  (IEA)
inflammatory response  (IGI,ISO,TAS)
inflammatory response to wounding  (IDA,ISO)
intrinsic apoptotic signaling pathway in response to DNA damage  (IDA)
JNK cascade  (IDA,IGI)
leukocyte migration  (IDA)
leukocyte migration involved in inflammatory response  (ISO)
leukocyte tethering or rolling  (ISO)
liver regeneration  (ISO)
macrophage activation involved in immune response  (IMP)
microglial cell activation  (IDA,TAS)
necroptotic signaling pathway  (IGI,ISO)
negative regulation of amyloid-beta clearance  (IGI)
negative regulation of apoptotic process  (ISO)
negative regulation of apoptotic signaling pathway  (ISO)
negative regulation of bicellular tight junction assembly  (ISO)
negative regulation of bile acid secretion  (ISO)
negative regulation of blood vessel endothelial cell migration  (ISO)
negative regulation of branching involved in lung morphogenesis  (ISO)
negative regulation of cell population proliferation  (ISO)
negative regulation of cytokine production involved in immune response  (ISO)
negative regulation of DNA-templated transcription  (ISO)
negative regulation of endothelial cell proliferation  (IDA)
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand  (ISO)
negative regulation of fat cell differentiation  (ISO)
negative regulation of gene expression  (IDA,ISO)
negative regulation of glucose import  (IDA,ISO)
negative regulation of heart rate  (ISO)
negative regulation of insulin receptor signaling pathway  (TAS)
negative regulation of interleukin-6 production  (ISO)
negative regulation of L-glutamate import across plasma membrane  (ISO)
negative regulation of lipid catabolic process  (ISO)
negative regulation of mitotic cell cycle  (IDA)
negative regulation of myelination  (ISO)
negative regulation of myoblast differentiation  (IMP)
negative regulation of osteoblast differentiation  (IDA)
negative regulation of oxidative phosphorylation  (ISO)
negative regulation of protein-containing complex disassembly  (ISO)
negative regulation of systemic arterial blood pressure  (ISO)
negative regulation of transcription by RNA polymerase II  (IDA,ISO)
negative regulation of vascular wound healing  (ISO)
negative regulation of viral genome replication  (ISO)
osteoclast differentiation  (IGI)
phosphatidylinositol 3-kinase/protein kinase B signal transduction  (IDA)
positive regulation of action potential  (ISO)
positive regulation of amide metabolic process  (IDA)
positive regulation of amyloid-beta formation  (IDA)
positive regulation of apoptotic process  (ISO)
positive regulation of blood microparticle formation  (ISO)
positive regulation of calcineurin-NFAT signaling cascade  (ISO)
positive regulation of canonical NF-kappaB signal transduction  (IBA,IDA,IGI,ISO)
positive regulation of cell adhesion  (ISO)
positive regulation of cell population proliferation  (TAS)
positive regulation of chemokine (C-X-C motif) ligand 2 production  (ISO)
positive regulation of chemokine production  (ISO)
positive regulation of chronic inflammatory response to antigenic stimulus  (IGI)
positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis  (ISO)
positive regulation of cytokine production  (ISO)
positive regulation of cytokine production involved in inflammatory response  (ISO)
positive regulation of DNA biosynthetic process  (ISO)
positive regulation of DNA-templated transcription  (IDA,ISO)
positive regulation of endothelial cell apoptotic process  (ISO)
positive regulation of estradiol secretion  (ISO)
positive regulation of extrinsic apoptotic signaling pathway  (IBA)
positive regulation of fever generation  (IDA)
positive regulation of fractalkine production  (ISO)
positive regulation of gene expression  (IDA,ISO)
positive regulation of glial cell proliferation  (ISO)
positive regulation of hair follicle development  (IMP)
positive regulation of hepatocyte proliferation  (ISO)
positive regulation of heterotypic cell-cell adhesion  (IDA,ISO)
positive regulation of humoral immune response mediated by circulating immunoglobulin  (IGI)
positive regulation of I-kappaB phosphorylation  (ISO)
positive regulation of interleukin-1 beta production  (ISO)
positive regulation of interleukin-18 production  (ISO)
positive regulation of interleukin-33 production  (ISO)
positive regulation of interleukin-6 production  (IDA,ISO)
positive regulation of interleukin-8 production  (ISO)
positive regulation of JNK cascade  (IDA,IGI)
positive regulation of leukocyte adhesion to arterial endothelial cell  (ISO)
positive regulation of leukocyte adhesion to vascular endothelial cell  (ISO)
positive regulation of lipid metabolic process  (IDA)
positive regulation of MAPK cascade  (ISO)
positive regulation of membrane protein ectodomain proteolysis  (ISO)
positive regulation of miRNA transcription  (ISO)
positive regulation of mitotic nuclear division  (ISO)
positive regulation of neuron apoptotic process  (IDA,ISO)
positive regulation of neutrophil activation  (ISO)
positive regulation of nitric oxide biosynthetic process  (ISO)
positive regulation of nitric-oxide synthase activity  (ISO)
positive regulation of nitrogen compound metabolic process  (IGI)
positive regulation of non-canonical NF-kappaB signal transduction  (IMP,ISO)
positive regulation of osteoclast differentiation  (ISO)
positive regulation of peptidyl-serine phosphorylation  (ISO)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction  (IDA,ISO)
positive regulation of podosome assembly  (ISO)
positive regulation of programmed cell death  (ISO)
positive regulation of protein catabolic process  (ISO)
positive regulation of protein localization to cell surface  (ISO)
positive regulation of protein localization to plasma membrane  (IMP,ISO)
positive regulation of protein phosphorylation  (ISO)
positive regulation of protein transport  (ISO)
positive regulation of protein-containing complex assembly  (ISO)
positive regulation of protein-containing complex disassembly  (ISO)
positive regulation of receptor signaling pathway via JAK-STAT  (ISO)
positive regulation of smooth muscle cell proliferation  (ISO)
positive regulation of synaptic transmission  (IMP,ISO)
positive regulation of synoviocyte proliferation  (ISO)
positive regulation of transcription by RNA polymerase II  (IBA,IDA,IGI,ISO)
positive regulation of translational initiation by iron  (IDA)
positive regulation of type II interferon production  (IGI)
positive regulation of tyrosine phosphorylation of STAT protein  (ISO)
positive regulation of vascular associated smooth muscle cell proliferation  (IDA)
positive regulation of vitamin D biosynthetic process  (ISO)
protein localization to plasma membrane  (ISO)
regulation of branching involved in salivary gland morphogenesis  (IDA,IMP)
regulation of canonical NF-kappaB signal transduction  (ISO)
regulation of cell population proliferation  (IDA,ISO)
regulation of endothelial cell apoptotic process  (ISO)
regulation of establishment of endothelial barrier  (ISO)
regulation of fat cell differentiation  (ISO)
regulation of immunoglobulin production  (IDA)
regulation of inflammatory response  (IDA)
regulation of insulin secretion  (ISO)
regulation of membrane lipid metabolic process  (IDA)
regulation of osteoclast differentiation  (IDA)
regulation of protein phosphorylation  (IDA)
regulation of protein secretion  (IDA)
regulation of reactive oxygen species metabolic process  (IDA)
regulation of synapse organization  (IMP)
response to 3,3',5-triiodo-L-thyronine  (ISO)
response to activity  (ISO)
response to bacterium  (ISO)
response to ethanol  (ISO)
response to fructose  (ISO)
response to glucocorticoid  (ISO)
response to gold nanoparticle  (ISO)
response to Gram-negative bacterium  (ISO)
response to hypoxia  (ISO)
response to isolation stress  (ISO)
response to L-glutamate  (ISO)
response to lipopolysaccharide  (ISO)
response to macrophage colony-stimulating factor  (ISO)
response to mechanical stimulus  (ISO)
response to nutrient levels  (ISO)
response to organic cyclic compound  (ISO)
response to organic substance  (IDA)
response to virus  (ISO)
response to xenobiotic stimulus  (ISO)
sequestering of triglyceride  (ISO)
signal transduction  (IDA)
skeletal muscle contraction  (ISO)
toll-like receptor 3 signaling pathway  (ISO)
tumor necrosis factor-mediated signaling pathway  (IBA,IDA,ISO,TAS)
vascular endothelial growth factor production  (ISO)
vasodilation  (ISO)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal alpha-beta intraepithelial T cell morphology  (IAGP)
abnormal aorta bulb morphology  (IAGP)
abnormal aortic valve flow  (IAGP)
abnormal aortic valve morphology  (IAGP)
abnormal CD4-positive, alpha-beta T cell physiology  (IAGP)
abnormal CD8-positive, alpha beta T cell morphology  (IAGP)
abnormal cell adhesion  (IAGP)
abnormal cell cycle  (IAGP)
abnormal cell physiology  (IAGP)
abnormal cerebral cortex morphology  (IAGP)
abnormal chemokine secretion  (IAGP)
abnormal circulating chemokine level  (IAGP)
abnormal circulating leptin level  (IAGP)
abnormal class switch recombination  (IAGP)
abnormal cytokine level  (IAGP)
abnormal cytokine secretion  (IAGP)
abnormal cytotoxic T cell physiology  (IAGP)
abnormal embryo morphology  (IAGP)
abnormal epidermal layer morphology  (IAGP)
abnormal epidermis stratum basale morphology  (IAGP)
abnormal fat pad morphology  (IAGP)
abnormal female reproductive system physiology  (IAGP)
abnormal fibroblast physiology  (IAGP)
abnormal follicular dendritic cell physiology  (IAGP)
abnormal food intake  (IAGP)
abnormal gamma-delta T cell morphology  (IAGP)
abnormal glucose homeostasis  (IAGP)
abnormal hair follicle placode formation  (IAGP)
abnormal humoral immune response  (IAGP)
abnormal immune system physiology  (IAGP)
abnormal inflammatory response  (IAGP)
abnormal intestinal mucosa morphology  (IAGP)
abnormal intestine physiology  (IAGP)
abnormal joint morphology  (IAGP)
abnormal keratinocyte morphology  (IAGP)
abnormal limb morphology  (IAGP)
abnormal lipid homeostasis  (IAGP)
abnormal liver physiology  (IAGP)
abnormal long-term spatial reference memory  (IAGP)
abnormal lung morphology  (IAGP)
abnormal lymph node B cell domain morphology  (IAGP)
abnormal lymph node cell ratio  (IAGP)
abnormal lymph node primary follicle morphology  (IAGP)
abnormal lymphocyte physiology  (IAGP)
abnormal macrophage physiology  (IAGP)
abnormal mesenteric lymph node morphology  (IAGP)
abnormal metallophilic macrophage morphology  (IAGP)
abnormal motor coordination/balance  (IAGP)
abnormal myelopoiesis  (IAGP)
abnormal myogenesis  (IAGP)
abnormal nervous system physiology  (IAGP)
abnormal neutrophil physiology  (IAGP)
abnormal osteoclast differentiation  (IAGP)
abnormal Peyer's patch follicle morphology  (IAGP)
abnormal Peyer's patch germinal center morphology  (IAGP)
abnormal Peyer's patch morphology  (IAGP)
abnormal Peyer's patch T cell area morphology  (IAGP)
abnormal response to transplant  (IAGP)
abnormal retina morphology  (IAGP)
abnormal rib joint morphology  (IAGP)
abnormal sleep pattern  (IAGP)
abnormal small intestinal villus morphology  (IAGP)
abnormal spermatogenesis  (IAGP)
abnormal spermiation  (IAGP)
abnormal spine curvature  (IAGP)
abnormal spleen B cell follicle morphology  (IAGP)
abnormal spleen follicular dendritic cell network  (IAGP)
abnormal spleen marginal sinus morphology  (IAGP)
abnormal spleen marginal zone morphology  (IAGP)
abnormal spleen morphology  (IAGP)
abnormal spleen primary B follicle morphology  (IAGP)
abnormal spleen white pulp morphology  (IAGP)
abnormal susceptibility to infection  (IAGP)
abnormal T cell physiology  (IAGP)
abnormal T cell subpopulation ratio  (IAGP)
abnormal T-helper 17 cell physiology  (IAGP)
abnormal testis physiology  (IAGP)
abnormal thoracic vertebrae morphology  (IAGP)
abnormal trabecular bone morphology  (IAGP)
abnormal vagina weight  (IAGP)
abnormal vasodilation  (IAGP)
abnormal wound healing  (IAGP)
abnormal wrist joint morphology  (IAGP)
absent axillary lymph nodes  (IAGP)
absent brachial lymph nodes  (IAGP)
absent cervical lymph nodes  (IAGP)
absent follicular dendritic cells  (IAGP)
absent germinal center B cells  (IAGP)
absent inguinal lymph nodes  (IAGP)
absent lymph node germinal center  (IAGP)
absent lymph nodes  (IAGP)
absent mesenteric lymph nodes  (IAGP)
absent peripheral lymph nodes  (IAGP)
absent Peyer's patches  (IAGP)
absent popliteal lymph nodes  (IAGP)
absent spleen germinal center  (IAGP)
absent spleen marginal zone  (IAGP)
accelerated temporomandibular joint osteoarthritis  (IAGP)
alopecia  (IAGP)
alveolar process atrophy  (IAGP)
aortic aneurysm  (IAGP)
aortic valve inflammation  (IAGP)
aortic valve stenosis  (IAGP)
arthritis  (IAGP)
autoimmune response  (IAGP)
cachexia  (IAGP)
cardiac fibrosis  (IAGP)
cardiac valve regurgitation  (IAGP)
cardiovalvulitis  (IAGP)
cecum inflammation  (IAGP)
colitis  (IAGP)
conjunctivitis  (IAGP)
decreased apoptosis  (IAGP)
decreased body weight  (IAGP)
decreased cardiac output  (IAGP)
decreased cell proliferation  (IAGP)
decreased circulating glucose level  (IAGP)
decreased circulating insulin level  (IAGP)
decreased circulating interferon-gamma level  (IAGP)
decreased circulating interleukin-1 alpha level  (IAGP)
decreased circulating interleukin-1 beta level  (IAGP)
decreased circulating interleukin-6 level  (IAGP)
decreased circulating leptin level  (IAGP)
decreased circulating triglyceride level  (IAGP)
decreased circulating tumor necrosis factor level  (IAGP)
decreased coping response  (IAGP)
decreased cytotoxic T cell cytolysis  (IAGP)
decreased embryo size  (IAGP)
decreased follicular dendritic cell number  (IAGP)
decreased gamma-delta intraepithelial T cell number  (IAGP)
decreased grip strength  (IAGP)
decreased hair follicle number  (IAGP)
decreased heart rate  (IAGP)
decreased IgA level  (IAGP)
decreased IgG level  (IAGP)
decreased IgG1 level  (IAGP)
decreased IgG2a level  (IAGP)
decreased IgG3 level  (IAGP)
decreased immunoglobulin level  (IAGP)
decreased incidence of tumors by chemical induction  (IAGP)
decreased inflammatory response  (IAGP)
decreased interferon-gamma secretion  (IAGP)
decreased keratinocyte proliferation  (IAGP)
decreased liver free fatty acids level  (IAGP)
decreased locomotor activity  (IAGP)
decreased macrophage cytokine production  (IEA)
decreased Paneth cell number  (IAGP)
decreased percent body fat/body weight  (IAGP)
decreased Peyer's patch number  (IAGP)
decreased skeletal muscle fiber diameter  (IAGP)
decreased small intestinal villus number  (IAGP)
decreased spleen B cell follicle number  (IAGP)
decreased spleen germinal center number  (IAGP)
decreased spleen germinal center size  (IAGP)
decreased spleen white pulp amount  (IAGP)
decreased susceptibility to autoimmune disorder  (IAGP)
decreased susceptibility to bacterial infection  (IAGP)
decreased susceptibility to diet-induced obesity  (IAGP)
decreased susceptibility to endotoxin shock  (IAGP)
decreased susceptibility to experimental autoimmune encephalomyelitis  (IAGP)
decreased susceptibility to induced arthritis  (IAGP)
decreased susceptibility to induced morbidity/mortality  (IAGP)
decreased susceptibility to parasitic infection  (IAGP)
decreased susceptibility to type IV hypersensitivity reaction  (IAGP)
decreased T cell number  (IAGP)
decreased testes secretion  (IAGP)
decreased testis weight  (IAGP)
decreased tumor necrosis factor secretion  (IAGP)
decreased ventricle muscle contractility  (IAGP)
decreased vertical activity  (IAGP)
dermatitis  (IAGP)
dilated heart left ventricle  (IAGP)
enhanced wound healing  (IAGP)
enlarged liver  (IAGP)
enlarged spleen  (IAGP)
esophageal inflammation  (IAGP)
eyelid edema  (IAGP)
granulomatous inflammation  (IAGP)
hepatic necrosis  (IAGP)
hepatic steatosis  (IAGP)
hindlimb paralysis  (IAGP)
ileum inflammation  (IAGP)
impaired coordination  (IAGP)
impaired macrophage phagocytosis  (IAGP)
increased anxiety-related response  (IAGP)
increased apoptosis  (IAGP)
increased B cell number  (IAGP)
increased body length  (IAGP)
increased body mass index  (IAGP)
increased body weight  (IAGP)
increased bone mineral density  (IAGP)
increased CD4-positive, alpha-beta memory T cell number  (IAGP)
increased CD4-positive, alpha-beta T cell number  (IAGP)
increased CD8-positive, alpha-beta T cell number  (IAGP)
increased cell migration  (IAGP)
increased cell proliferation  (IAGP)
increased circulating tumor necrosis factor level  (IAGP)
increased dendritic cell number  (IAGP)
increased fibroblast cell migration  (IAGP)
increased fibroblast proliferation  (IAGP)
increased grooming behavior  (IAGP)
increased heart weight  (IAGP)
increased IgM level  (IAGP)
increased interferon-gamma secretion  (IAGP)
increased interleukin-12b secretion  (IAGP)
increased interleukin-2 secretion  (IAGP)
increased interleukin-6 secretion  (IAGP)
increased leukocyte cell number  (IAGP)
increased liver weight  (IAGP)
increased lymphocyte cell number  (IAGP)
increased neutrophil cell number  (IAGP)
increased osteoblast cell number  (IAGP)
increased serotonin level  (IAGP)
increased single-positive T cell number  (IAGP)
increased skeletal muscle fiber number  (IAGP)
increased spleen weight  (IAGP)
increased susceptibility to bacterial infection  (IAGP)
increased susceptibility to bacterial infection induced morbidity/mortality  (IAGP)
increased susceptibility to diet-induced obesity  (IAGP)
increased susceptibility to endotoxin shock  (IAGP)
increased susceptibility to fungal infection  (IAGP)
increased susceptibility to induced morbidity/mortality  (IAGP)
increased susceptibility to injury  (IAGP)
increased susceptibility to parasitic infection  (IAGP)
increased susceptibility to Poxviridae infection  (IAGP)
increased susceptibility to Riboviria infection  (IAGP)
increased tumor necrosis factor secretion  (IAGP)
intermingled spleen red and white pulp  (IAGP)
intestinal inflammation  (IAGP)
joint dislocation  (IAGP)
joint inflammation  (IAGP)
kyphosis  (IAGP)
large intestinal inflammation  (IAGP)
lethality throughout fetal growth and development, complete penetrance  (IAGP)
limb paralysis  (IAGP)
long tibia  (IAGP)
lung inflammation  (IAGP)
lymph node hypoplasia  (IAGP)
mitral valve inflammation  (IAGP)
myeloid hyperplasia  (IAGP)
neonatal lethality, complete penetrance  (IAGP)
oligozoospermia  (IAGP)
oxidative stress  (IAGP)
perinatal lethality, incomplete penetrance  (IAGP)
postnatal lethality  (IAGP)
premature death  (IAGP)
prenatal lethality, complete penetrance  (IAGP)
prenatal lethality, incomplete penetrance  (IAGP)
preweaning lethality, incomplete penetrance  (IAGP)
prolonged estrus  (IAGP)
prolonged QT interval  (IAGP)
retina neovascularization  (IMP)
retina photoreceptor degeneration  (IAGP)
rheumatoid arthritis  (IAGP)
skin inflammation  (IAGP)
skin lesions  (IAGP)
small intestinal inflammation  (IAGP)
small Peyer's patches  (IAGP)
steatorrhea  (IAGP)
thick aortic valve  (IAGP)
thick aortic valve cusps  (IAGP)
thick mitral valve  (IAGP)
thin epidermis  (IAGP)
thin retina inner nuclear layer  (IAGP)
thin retina outer nuclear layer  (IAGP)
thymus hypoplasia  (IAGP)
underdeveloped hair follicles  (IAGP)
weight loss  (IAGP)
References

References - curated
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7. Tumor necrosis factor-alpha levels and promoter polymorphism in patients with Kawasaki disease in Korea. Ahn SY, etal., Yonsei Med J. 2003 Dec 30;44(6):1021-6.
8. Plasma cytokine levels in patients with obstructive sleep apnea syndrome: a preliminary study. Alberti A, etal., J Sleep Res. 2003 Dec;12(4):305-11.
9. Serum evaluation of angiogenic cytokine basic fibroblast growth factor, hepatocyte growth factor and TNF-alpha in patients with myelodysplastic syndromes: correlation with bone marrow microvascular density. Alexandrakis MG, etal., Int J Immunopathol Pharmacol. 2005 Apr-Jun;18(2):287-95.
10. Measurement of mRNA expression for a variety of cytokines and its receptors in bone marrows of patients with myelodysplastic syndromes. Allampallam K, etal., Anticancer Res. 1999 Nov-Dec;19(6B):5323-8.
11. TNF-alpha levels and TNF-alpha gene polymorphism in type I Gaucher disease. Altarescu G, etal., Cytokine. 2005 Jul 21;31(2):149-52.
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13. Effect of low-level laser therapy on the expression of inflammatory mediators and on neutrophils and macrophages in acute joint inflammation. Alves AC, etal., Arthritis Res Ther. 2013;15(5):R116.
14. Ablation of T-helper 1 cell derived cytokines and of monocyte-derived tumor necrosis factor-alpha in hereditary hemorrhagic telangiectasia: immunological consequences and clinical considerations. Amati L, etal., Curr Pharm Des. 2006;12(10):1201-8.
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17. High circulating N-terminal pro-brain natriuretic peptide and tumor necrosis factor-alpha in mixed cryoglobulinemia. Antonelli A, etal., World J Gastroenterol. 2009 Oct 28;15(40):5074-9.
18. Characterization of the innate immune response to chronic aspiration in a novel rodent model. Appel JZ 3rd, etal., Respir Res. 2007 Nov 27;8:87.
19. TNF-α and IL-10 polymorphisms increase the risk to hepatocellular carcinoma in HCV infected individuals. Aroucha DC, etal., J Med Virol. 2016 Sep;88(9):1587-95. doi: 10.1002/jmv.24501. Epub 2016 Mar 21.
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21. Lack of association of tumor necrosis factor-alpha gene polymorphisms with disease susceptibility and severity in Behçet's disease. Ates A, etal., Rheumatol Int. 2006 Feb;26(4):348-53. Epub 2005 May 5.
22. Tumor necrosis factor SNP haplotypes are associated with iron deficiency anemia in West African children. Atkinson SH, etal., Blood. 2008 Nov 15;112(10):4276-83. doi: 10.1182/blood-2008-06-162008. Epub 2008 Aug 20.
23. Intra-arterial administration of TNF-alpha followed by arterial ablation is an effective therapy for a regionally confined TNF-resistant rat mammary adenocarcinoma. Badgwell BD, etal., Cancer Immunol Immunother. 2003 Jan;52(1):10-6. doi: 10.1007/s00262-002-0330-2. Epub 2002 Nov 1.
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27. Moxibustion inhibits apoptosis and tumor necrosis factor-alpha/tumor necrosis factor receptor 1 in the colonic epithelium of Crohn's disease model rats. Bao CH, etal., Dig Dis Sci. 2012 Sep;57(9):2286-95. doi: 10.1007/s10620-012-2161-0. Epub 2012 Apr 25.
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32. Targeted therapy of renal cell carcinoma: synergistic activity of cG250-TNF and IFNg. Bauer S, etal., Int J Cancer. 2009 Jul 1;125(1):115-23.
33. Association between tumor necrosis factor-alpha gene promoter polymorphism at position -308 and acne in Turkish patients. Baz K, etal., Arch Dermatol Res. 2008 Aug;300(7):371-6. doi: 10.1007/s00403-008-0871-0. Epub 2008 Jul 10.
34. Association of tumor necrosis factor and human leukocyte antigen DRB1 alleles with Graves' ophthalmopathy. Bednarczuk T, etal., Hum Immunol. 2004 Jun;65(6):632-9.
35. Deleterious role of TNF-alpha in retinal ischemia-reperfusion injury. Berger S, etal., Invest Ophthalmol Vis Sci. 2008 Aug;49(8):3605-10. doi: 10.1167/iovs.07-0817.
36. New insights into the pathological role of TNF-alpha in early cardiac dysfunction and subsequent heart failure after infarction in rats. Berthonneche C, etal., Am J Physiol Heart Circ Physiol. 2004 Jul;287(1):H340-50.
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38. TNF-alpha gene polymorphism and TNF-alpha levels in obese Asian Indians with obstructive sleep apnea. Bhushan B, etal., Respir Med. 2009 Mar;103(3):386-92. Epub 2008 Nov 20.
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42. Intracellular tumor necrosis factor production by T- and B-cells in B-cell chronic lymphocytic leukemia. Bojarska-Junak A, etal., Haematologica. 2002 May;87(5):490-9.
43. Primary infection of mice with high titer inoculum respiratory syncytial virus: characterization and response to antiviral therapy. Bolger G, etal., Can J Physiol Pharmacol. 2005 Feb;83(2):198-213.
44. Interleukin-10 and tumor necrosis factor-alpha single nucleotide gene polymorphism frequency in paracoccidioidomycosis. Bozzi A, etal., Hum Immunol. 2006 Nov;67(11):931-9. Epub 2006 Sep 1.
45. Gene polymorphism at position -308 of the tumor-necrosis-factor-alpha (TNF-alpha) in multiple sclerosis and it's influence on the regulation of TNF-alpha production. Braun N, etal., Neurosci Lett. 1996 Sep 6;215(2):75-8.
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47. TNFR2 interposes the proliferative and NF-kappaB-mediated inflammatory response by podocytes to TNF-alpha. Bruggeman LA, etal., Lab Invest. 2011 Mar;91(3):413-25. doi: 10.1038/labinvest.2010.199. Epub 2011 Jan 10.
48. Lack of association between atopic asthma and the tumor necrosis factor alpha-308 gene polymorphism in a Czech population. Buckova D, etal., J Investig Allergol Clin Immunol. 2002;12(3):192-7.
49. Polymorphism in tumor necrosis factor genes associated with mucocutaneous leishmaniasis. Cabrera M, etal., J Exp Med. 1995 Nov 1;182(5):1259-64.
50. Exercise training improves the IL-10/TNF-α cytokine balance in the gastrocnemius of rats with heart failure. Calegari L, etal., Braz J Phys Ther. 2018 Mar - Apr;22(2):154-160. doi: 10.1016/j.bjpt.2017.09.004. Epub 2017 Sep 7.
51. Hypothermia after cardiac arrest does not alter serum inflammatory markers. Callaway CW, etal., Crit Care Med. 2008 Sep;36(9):2607-12.
52. Hepatic ischemia/reperfusion injury is diminished by atorvastatin in Wistar rats. Camara-Lemarroy CR, etal., Arch Med Res. 2014 Apr;45(3):210-6. doi: 10.1016/j.arcmed.2014.02.001. Epub 2014 Apr 13.
53. Effect of sulfasalazine on renal ischemia/reperfusion injury in rats. Camara-Lemarroy CR, etal., Ren Fail. 2009;31(9):822-8.
54. ZFP36 protects lungs from intestinal I/R-induced injury and fibrosis through the CREBBP/p53/p21/Bax pathway. Cao Y, etal., Cell Death Dis. 2021 Jul 8;12(7):685. doi: 10.1038/s41419-021-03950-y.
55. Myelodysplasia and anemia of chronic disease in human tumor necrosis factor-alpha transgenic mice. Capocasale RJ, etal., Cytometry A. 2008 Feb;73(2):148-59. doi: 10.1002/cyto.a.20512.
56. Joint effect of obesity and TNFA variability on asthma: two international cohort studies. Castro-Giner F, etal., Eur Respir J. 2009 May;33(5):1003-9. Epub 2009 Feb 5.
57. Polymorphism in the TNF-alpha gene promoter at position -1031 is associated with increased circulating levels of TNF-alpha, myeloperoxidase and nitrotyrosine in primary Sjogren's syndrome. Cay HF, etal., Clin Exp Rheumatol. 2012 Nov-Dec;30(6):843-9. Epub 2012 Dec 17.
58. Anti-inflammatory effects of low molecular weight heparin derivative in a rat model of carrageenan-induced pleurisy. Ceccarelli M, etal., J Cell Mol Med. 2009 Aug;13(8B):2704-12.
59. Granzyme-b is involved in mediating post-ischemic neuronal death during focal cerebral ischemia in rat model. Chaitanya GV, etal., Neuroscience. 2010 Feb 17;165(4):1203-16. Epub 2009 Nov 4.
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PMID:27184845   PMID:27185876   PMID:27211851   PMID:27226618   PMID:27230858   PMID:27240831   PMID:27256566   PMID:27257617   PMID:27260954   PMID:27264187   PMID:27268285   PMID:27273006  
PMID:27288458   PMID:27292196   PMID:27292635   PMID:27311810   PMID:27311858   PMID:27314319   PMID:27318131   PMID:27324279   PMID:27349859   PMID:27365293   PMID:27365402   PMID:27369778  
PMID:27374884   PMID:27384243   PMID:27391954   PMID:27395777   PMID:27408775   PMID:27432943   PMID:27447669   PMID:27456129   PMID:27476761   PMID:27492217   PMID:27503807   PMID:27505147  
PMID:27506541   PMID:27515532   PMID:27515767   PMID:27526711   PMID:27552480   PMID:27556180   PMID:27560715   PMID:27562094   PMID:27591224   PMID:27591508   PMID:27595832   PMID:27596364  
PMID:27632536   PMID:27635406   PMID:27653694   PMID:27659424   PMID:27692610   PMID:27706765   PMID:27712936   PMID:27732846   PMID:27735938   PMID:27746173   PMID:27750040   PMID:27752902  
PMID:27760760   PMID:27814300   PMID:27820699   PMID:27830702   PMID:27832973   PMID:27853236   PMID:27863204   PMID:27863332   PMID:27911957   PMID:27914456   PMID:27979472   PMID:27979975  
PMID:27982014   PMID:28017833   PMID:28039479   PMID:28059444   PMID:28063705   PMID:28063995   PMID:28064242   PMID:28079895   PMID:28088582   PMID:28093554   PMID:28095415   PMID:28096297  
PMID:28096401   PMID:28099414   PMID:28100666   PMID:28100745   PMID:28109179   PMID:28111081   PMID:28122986   PMID:28123022   PMID:28130856   PMID:28131916   PMID:28160574   PMID:28162974  
PMID:28183530   PMID:28184968   PMID:28204823   PMID:28215713   PMID:28264935   PMID:28287124   PMID:28330904   PMID:28345588   PMID:28349965   PMID:28358362   PMID:28358372   PMID:28379965  
PMID:28396236   PMID:28399411   PMID:28410990   PMID:28422748   PMID:28438992   PMID:28439030   PMID:28442538   PMID:28444900   PMID:28447740   PMID:28483582   PMID:28489068   PMID:28497109  
PMID:28504723   PMID:28506461   PMID:28543680   PMID:28545808   PMID:28546545   PMID:28570274   PMID:28574501   PMID:28575756   PMID:28580280   PMID:28619762   PMID:28637883   PMID:28666573  
PMID:28671989   PMID:28688761   PMID:28701229   PMID:28731277   PMID:28746871   PMID:28747340   PMID:28756234   PMID:28758900   PMID:28796256   PMID:28800644   PMID:28801579   PMID:28811474  
PMID:28823863   PMID:28826177   PMID:28842479   PMID:28849104   PMID:28852052   PMID:28874664   PMID:28890718   PMID:28892415   PMID:28902427   PMID:28910376   PMID:28912506   PMID:28917655  
PMID:28922680   PMID:28947753   PMID:28965953   PMID:28974711   PMID:29018280   PMID:29040534   PMID:29072682   PMID:29095915   PMID:29101349   PMID:29113822   PMID:29130929   PMID:29132095  
PMID:29138464   PMID:29143372   PMID:29162452   PMID:29175304   PMID:29195897   PMID:29199072   PMID:29203883   PMID:29217508   PMID:29234064   PMID:29238068   PMID:29242588   PMID:29273790  
PMID:29286110   PMID:29322353   PMID:29329948   PMID:29330412   PMID:29339399   PMID:29391475   PMID:29401621   PMID:29403488   PMID:29434332   PMID:29437957   PMID:29438518   PMID:29445073  
PMID:29445180   PMID:29465304   PMID:29465830   PMID:29476069   PMID:29500178   PMID:29500244   PMID:29512766   PMID:29513410   PMID:29532456   PMID:29558472   PMID:29559745   PMID:29563178  
PMID:29563337   PMID:29570119   PMID:29596938   PMID:29608550   PMID:29618659   PMID:29649942   PMID:29657255   PMID:29696511   PMID:29702281   PMID:29723540   PMID:29724065   PMID:29724888  
PMID:29724913   PMID:29728804   PMID:29741644   PMID:29746256   PMID:29749399   PMID:29765402   PMID:29776906   PMID:29776993   PMID:29791904   PMID:29798841   PMID:29800552   PMID:29802833  
PMID:29847081   PMID:29849090   PMID:29872095   PMID:29891719   PMID:29930103   PMID:29940243   PMID:29969604   PMID:29973541   PMID:30033139   PMID:30035749   PMID:30042130   PMID:30048240  
PMID:30072733   PMID:30073573   PMID:30085101   PMID:30097714   PMID:30107066   PMID:30114280   PMID:30114984   PMID:30143634   PMID:30146158   PMID:30174297   PMID:30181240   PMID:30209212  
PMID:30216540   PMID:30232332   PMID:30244178   PMID:30256507   PMID:30301719   PMID:30327532   PMID:30354252   PMID:30361263   PMID:30389199   PMID:30389698   PMID:30394583   PMID:30397205  
PMID:30398566   PMID:30407559   PMID:30420664   PMID:30456702   PMID:30457980   PMID:30463004   PMID:30498033   PMID:30510188   PMID:30515151   PMID:30532756   PMID:30540940   PMID:30544870  
PMID:30571485   PMID:30582235   PMID:30610060   PMID:30631042   PMID:30635041   PMID:30635238   PMID:30664762   PMID:30717817   PMID:30755793   PMID:30776316   PMID:30796945   PMID:30860638  
PMID:30936247   PMID:30938680   PMID:30944411   PMID:30980570   PMID:30996002   PMID:31004466   PMID:31017694   PMID:31026287   PMID:31049124   PMID:31057027   PMID:31073040   PMID:31092054  
PMID:31125264   PMID:31194726   PMID:31211773   PMID:31230859   PMID:31243089   PMID:31296735   PMID:31301888   PMID:31341915   PMID:31352002   PMID:31378003   PMID:31450968   PMID:31462647  
PMID:31486675   PMID:31505254   PMID:31519887   PMID:31525456   PMID:31529816   PMID:31552020   PMID:31561945   PMID:31562208   PMID:31570507   PMID:31576092   PMID:31578352   PMID:31618254  
PMID:31637886   PMID:31657476   PMID:31677795   PMID:31682627   PMID:31721276   PMID:31736350   PMID:31759325   PMID:31760229   PMID:31813248   PMID:31825818   PMID:31840058   PMID:31846439  
PMID:31848486   PMID:31852844   PMID:31886238   PMID:31891805   PMID:31907354   PMID:31970902   PMID:31975434   PMID:31980603   PMID:31991752   PMID:32004684   PMID:32022429   PMID:32075762  
PMID:32094226   PMID:32101016   PMID:32101731   PMID:32103173   PMID:32190663   PMID:32205880   PMID:32234472   PMID:32277785   PMID:32296175   PMID:32419317   PMID:32424229   PMID:32449525  
PMID:32457323   PMID:32503845   PMID:32522975   PMID:32527376   PMID:32532183   PMID:32540999   PMID:32560900   PMID:32569771   PMID:32571912   PMID:32579912   PMID:32579923   PMID:32625209  
PMID:32652549   PMID:32662821   PMID:32708537   PMID:32719333   PMID:32731392   PMID:32732898   PMID:32892421   PMID:32941525   PMID:32963013   PMID:32989095   PMID:32992926   PMID:33049219  
PMID:33080865   PMID:33126536   PMID:33131307   PMID:33147455   PMID:33153044   PMID:33165593   PMID:33179086   PMID:33210082   PMID:33238518   PMID:33255553   PMID:33314792   PMID:33484643  
PMID:33513343   PMID:33525436   PMID:33559894   PMID:33586672   PMID:33620118   PMID:33760163   PMID:33803476   PMID:33814270   PMID:33846639   PMID:33889824   PMID:33914811   PMID:33917855  
PMID:33924148   PMID:33969572   PMID:33972436   PMID:34016976   PMID:34022882   PMID:34052361   PMID:34088851   PMID:34140389   PMID:34188052   PMID:34233954   PMID:34348145   PMID:34359856  
PMID:34369383   PMID:34395439   PMID:34400780   PMID:34498735   PMID:34511110   PMID:34529751   PMID:34534548   PMID:34550328   PMID:34556023   PMID:34565380   PMID:34613772   PMID:34621265  
PMID:34756873   PMID:34758308   PMID:34766371   PMID:34788601   PMID:34797693   PMID:34831454   PMID:34853447   PMID:34919331   PMID:34965421   PMID:34974067   PMID:35011604   PMID:35058362  
PMID:35077396   PMID:35139355   PMID:35293576   PMID:35312688   PMID:35314399   PMID:35372108   PMID:35383266   PMID:35409236   PMID:35464065   PMID:35474517   PMID:35493520   PMID:35609421  
PMID:35657353   PMID:35727972   PMID:35741098   PMID:35775903   PMID:35790400   PMID:35792863   PMID:35820612   PMID:35859175   PMID:35866513   PMID:35900193   PMID:35939138   PMID:35993019  
PMID:36076559   PMID:36104437   PMID:36150609   PMID:36182699   PMID:36183840   PMID:36191961   PMID:36207400   PMID:36274060   PMID:36398584   PMID:36403190   PMID:36414671   PMID:36499472  
PMID:36517241   PMID:36522157   PMID:36591221   PMID:36623778   PMID:36640256   PMID:36645344   PMID:36881482   PMID:36890117   PMID:36917193   PMID:36980752   PMID:36983072   PMID:37001596  
PMID:37021418   PMID:37040844   PMID:37048092   PMID:37085057   PMID:37115584   PMID:37142087   PMID:37169343   PMID:37178508   PMID:37261543   PMID:37261911   PMID:37317560   PMID:37459052  
PMID:37499863   PMID:37553427   PMID:37576598   PMID:37598207   PMID:37643009   PMID:37683301   PMID:37686246   PMID:37702066   PMID:37713664   PMID:37718683   PMID:37789765   PMID:37848095  
PMID:37879102   PMID:37914098   PMID:37940071   PMID:37948457   PMID:37967220   PMID:37986166   PMID:37993094   PMID:38054905   PMID:38195497   PMID:38218976   PMID:38241841   PMID:38256229  


Genomics

Comparative Map Data
Tnf
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391735,418,343 - 35,420,983 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1735,418,357 - 35,420,983 (-)EnsemblGRCm39 Ensembl
GRCm381735,199,367 - 35,202,007 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1735,199,381 - 35,202,007 (-)EnsemblGRCm38mm10GRCm38
MGSCv371735,336,335 - 35,338,941 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361734,807,442 - 34,810,048 (-)NCBIMGSCv36mm8
Celera1738,296,090 - 38,298,699 (-)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1718.59NCBI
TNF
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38631,575,565 - 31,578,336 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl631,575,565 - 31,578,336 (+)EnsemblGRCh38hg38GRCh38
GRCh37631,543,342 - 31,546,113 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36631,651,329 - 31,654,091 (+)NCBINCBI36Build 36hg18NCBI36
Build 34631,651,328 - 31,654,091NCBI
Celera633,141,565 - 33,144,327 (+)NCBICelera
Cytogenetic Map6p21.33NCBI
HuRef631,330,078 - 31,332,847 (+)NCBIHuRef
CHM1_1631,545,476 - 31,548,245 (+)NCBICHM1_1
T2T-CHM13v2.0631,428,617 - 31,431,388 (+)NCBIT2T-CHM13v2.0
Tnf
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8203,626,685 - 3,629,303 (+)NCBIGRCr8
mRatBN7.2203,622,011 - 3,624,629 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl203,622,011 - 3,624,629 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx204,321,864 - 4,324,463 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0203,683,924 - 3,686,523 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0204,221,516 - 4,224,112 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0205,189,382 - 5,192,000 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl205,189,390 - 5,192,000 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl204,855,829 - 4,858,447 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0206,936,229 - 6,938,847 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4203,661,000 - 3,663,618 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera204,400,860 - 4,403,478 (-)NCBICelera
RH 3.4 Map20 RGD
Cytogenetic Map20p12NCBI
Tnf
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955437117,206 - 120,700 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955437117,267 - 119,899 (+)NCBIChiLan1.0ChiLan1.0
TNF
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2546,052,507 - 46,055,280 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1642,014,074 - 42,016,847 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0631,236,650 - 31,239,423 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1632,126,618 - 32,129,389 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl632,126,618 - 32,129,381 (+)Ensemblpanpan1.1panPan2
TNF
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1121,074,561 - 1,076,425 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl121,074,552 - 1,076,425 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha121,211,002 - 1,212,867 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0121,219,807 - 1,221,672 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl121,219,798 - 1,221,672 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1121,078,543 - 1,080,407 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0121,146,468 - 1,148,336 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0121,213,251 - 1,215,120 (+)NCBIUU_Cfam_GSD_1.0
Tnf
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494635,623,427 - 35,626,009 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367271,936,066 - 1,937,766 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367271,936,066 - 1,937,766 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TNF
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl723,699,628 - 23,702,416 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1723,699,635 - 23,702,393 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2727,549,619 - 27,552,377 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap7p11-q11NCBI
TNF
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366604431,477,411 - 31,480,675 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tnf
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475424,623,425 - 24,625,531 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475424,623,059 - 24,625,647 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1241
Count of miRNA genes:478
Interacting mature miRNAs:552
Transcripts:ENSMUST00000025263, ENSMUST00000167924
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10412276Leci2_mleukocyte endothelial cell interactions 2 (mouse)Not determined17334817537348299Mouse
1300890Bhr3_mbronchial hyperresponsiveness 3 (mouse)Not determined17397489048866091Mouse
4141215Mnic1_mmacronutrient intake, carbohydrate 1 (mouse)Not determined485475245670266Mouse
1300706Alan1_malloantigen response 1 (mouse)Not determined17485475246469702Mouse
1357789Kdnw3_mkidney weight 3 (mouse)Not determined17485475247885665Mouse
4141272Tfv1_mtotal food volume 1 (mouse)Not determined485475265637357Mouse
10043949Pbft7_mpercent body fat 7 (mouse)Not determined17689393640893936Mouse
1301935Skull24_mskull morphology 24 (mouse)Not determined17858491442585149Mouse
1300787Cd8mts5_mCD8 memory T cell subset 5 (mouse)Not determined17858491442585149Mouse
1301338Lmr1_mleishmaniasis resistance 1 (mouse)Not determined171008134086996400Mouse
1302028Asbb3_mautoimmune susceptibility in C57BL/6J and BALB/c 3 (mouse)Not determined171087811944878219Mouse
4142342Lfnq4_mlung function QTL 4 (mouse)Not determined1120648439364059Mouse
4141067Hbnr2_mHeligmosomoides bakeri nematode resistance 2 (mouse)Not determined1188597145886119Mouse
14747010Mancz14_mmandible centroid size 14 (mouse)171199818445998184Mouse
4142150Stheal11_msoft tissue heal 11 (mouse)Not determined171228621183361768Mouse
12904946Tammq8_mtibialis anterior muscle mass QTL 8 (mouse)171245178746451787Mouse
13524847Asrq8a_macoustic startle response 8a (mouse)171264696146646961Mouse
11081168Tir7_mtrypanosome infection response 7 (mouse)171412337248123496Mouse
1300995Fembrs4_mfemur breaking strength 4 (mouse)Not determined171506165249061760Mouse
1300914Pcir4_mperiosteal circumference 4 (mouse)Not determined171506165249061760Mouse
1302070Tbbmd7_mtotal body bone mineral density 7 (mouse)Not determined171506165249061760Mouse
1558886Lgth9_mbody length 9 (mouse)Not determined171506165249061760Mouse
1302140Wta4_mweight adult 4 (mouse)Not determined171681972150819843Mouse
1302152Skull25_mskull morphology 25 (mouse)Not determined171681972150819843Mouse
10412083Sm2_msusceptibility to Schistosoma mansoni infection 2 (mouse)Not determined171702994351030078Mouse
13452396Leusq3_mleucocytosis susceptibility QTL 3 (mouse)171746220851462345Mouse
13452399Leusq6_mleucocytosis susceptibility QTL 6 (mouse)171746220851462345Mouse
10412214Sxbq3_mSGC/Knj cross B6 QTL 3 (mouse)Not determined171746220851462345Mouse
1300535Char3_mP. chabaudi malaria resistance QTL 3 (mouse)Not determined171746220851462345Mouse
1301840Ssial4_msusceptibility to sialadenitiss 4 (mouse)Not determined171817541252178214Mouse
1301331Lbw1_mlupus NZB x NZW 1 (mouse)Not determined171841835752420983Mouse
1301056Pas2_mpulmonary adenoma susceptibility 2 (mouse)Not determined171842214152424327Mouse
15039354Nmrs36_mNAFLD-associated magnetic resonance shift 36 (mouse)171914502553145025Mouse
1301454Eae5_msusceptibility to experimental allergic encephalomyelitis 5 (mouse)Not determined172461275058612864Mouse
10412198Sst5_msusceptibility to tuberculosis 5 (mouse)Not determined172507658355712970Mouse
10412196Bbaa28_mB.burgdorferi-associated arthritis 28 (mouse)Not determined172558491443976235Mouse
10412204Bbaa29_mB.burgdorferi-associated arthritis 29 (mouse)Not determined172605118560051352Mouse
1558758Kcal2_mkilocalorie 2 (mouse)Not determined172640101252911704Mouse
1300602Eye2_meye weight 2 (mouse)Not determined172650533741105037Mouse
1302005Loco2_mlocomotor activity 2 (mouse)Not determined172688497260885114Mouse
11075105Modc1_mmodifier of Odc1 (mouse)172771579245622654Mouse
15039348Nmrs37_mNAFLD-associated magnetic resonance shift 37 (mouse)172781520961815209Mouse
10045977Tir9_mtrypanosome infection response 9 (mouse)Not determined172787811943885114Mouse
1300703Uvbi2_mUVB induced immunosuppression 2 (mouse)Not determined172862240662622654Mouse
1300589Myaa2_mmodifier of Yaa 2 (mouse)Not determined173013255564132666Mouse
4141357Mrdq1_mmodifier of retinal degeneration QTL 1 (mouse)Not determined3098790348039703Mouse
4140955Plgr1_mplague resistance locus 1 (mouse)Not determined3103350065033630Mouse
1300692Blmpf1_mbleomycin-induced pulmonary fibrosis 1 (mouse)Not determined173206165237644775Mouse
25394538Skmw84_mskeletal muscle weight 84, TA (mouse)173266042635520036Mouse
26884379Skwq5_mskull length QTL 5, 5 week (mouse)173311897454107028Mouse
1302189Dps3_mdelta power in slow-wave sleep 3 (mouse)Not determined173381972136250180Mouse
1300885Mbis4_mMycobacterium bovis-induced systemic lupus erythematosus 4 (mouse)Not determined173517581770165926Mouse

Markers in Region
AW824221  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381735,199,439 - 35,199,566UniSTSGRCm38
MGSCv371735,336,384 - 35,336,511UniSTSGRCm37
Celera1738,296,139 - 38,296,266UniSTS
Cytogenetic Map17B1UniSTS
cM Map1719.06UniSTS
Whitehead/MRC_RH17481.43UniSTS
PMC112151P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381735,200,410 - 35,200,888UniSTSGRCm38
MGSCv371735,337,355 - 35,337,833UniSTSGRCm37
Celera1738,297,110 - 38,297,588UniSTS
Cytogenetic Map17B1UniSTS
cM Map1719.06UniSTS
PMC116546P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381735,200,238 - 35,200,408UniSTSGRCm38
MGSCv371735,337,183 - 35,337,353UniSTSGRCm37
Celera1738,296,938 - 38,297,108UniSTS
Cytogenetic Map17B1UniSTS
cM Map1719.06UniSTS
Tnf  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381735,202,236 - 35,202,337UniSTSGRCm38
MGSCv371735,339,181 - 35,339,282UniSTSGRCm37
Celera1738,298,939 - 38,299,040UniSTS
Cytogenetic Map17B1UniSTS
cM Map1719.06UniSTS
D20Wox3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381735,202,236 - 35,202,345UniSTSGRCm38
MGSCv371735,339,181 - 35,339,290UniSTSGRCm37
Celera1738,298,939 - 38,299,048UniSTS
Cytogenetic Map17B1UniSTS
cM Map1719.06UniSTS
Tnf  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381735,200,145 - 35,201,114UniSTSGRCm38
MGSCv371735,337,090 - 35,338,059UniSTSGRCm37
Celera1738,296,845 - 38,297,814UniSTS
Cytogenetic Map17B1UniSTS
Lta  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381735,203,276 - 35,203,660UniSTSGRCm38
MGSCv371735,340,221 - 35,340,605UniSTSGRCm37
Celera1738,299,979 - 38,300,363UniSTS
Cytogenetic Map17B1UniSTS
cM Map1719.06UniSTS
Tnf  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381735,199,852 - 35,199,962UniSTSGRCm38
MGSCv371735,336,797 - 35,336,907UniSTSGRCm37
Celera1738,296,552 - 38,296,662UniSTS
Cytogenetic Map17B1UniSTS
cM Map1719.06UniSTS
Tnf  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381735,200,161 - 35,200,554UniSTSGRCm38
MGSCv371735,337,106 - 35,337,499UniSTSGRCm37
Celera1738,296,861 - 38,297,254UniSTS
Cytogenetic Map17B1UniSTS
cM Map1719.06UniSTS
Tnf  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381735,200,131 - 35,201,099UniSTSGRCm38
MGSCv371735,337,076 - 35,338,044UniSTSGRCm37
Celera1738,296,831 - 38,297,799UniSTS
Cytogenetic Map17B1UniSTS
cM Map1719.06UniSTS
Tnf  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381735,202,247 - 35,202,354UniSTSGRCm38
MGSCv371735,339,192 - 35,339,299UniSTSGRCm37
Celera1738,298,950 - 38,299,057UniSTS
Cytogenetic Map17B1UniSTS
Tnf  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381735,202,251 - 35,202,354UniSTSGRCm38
MGSCv371735,339,196 - 35,339,299UniSTSGRCm37
Celera1738,298,954 - 38,299,057UniSTS
Cytogenetic Map17B1UniSTS
cM Map1719.06UniSTS
cM Map1419.5UniSTS
Tnf  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381735,200,332 - 35,201,744UniSTSGRCm38
MGSCv371735,337,277 - 35,338,689UniSTSGRCm37
Celera1738,297,032 - 38,298,447UniSTS
Cytogenetic Map17B1UniSTS
cM Map1719.06UniSTS
Tnf  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map17B1UniSTS
cM Map1719.06UniSTS
Tnf  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map17B1UniSTS
cM Map1719.06UniSTS
Tnf  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381735,200,209 - 35,200,883UniSTSGRCm38
MGSCv371735,337,154 - 35,337,828UniSTSGRCm37
Celera1738,296,909 - 38,297,583UniSTS
Cytogenetic Map17B1UniSTS
Tnf  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map17B1UniSTS
Tnf  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381735,200,436 - 35,201,837UniSTSGRCm38
MGSCv371735,337,381 - 35,338,782UniSTSGRCm37
Celera1738,297,136 - 38,298,540UniSTS
Cytogenetic Map17B1UniSTS
Lta  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381735,203,741 - 35,203,958UniSTSGRCm38
MGSCv371735,340,686 - 35,340,903UniSTSGRCm37
Celera1738,300,444 - 38,300,661UniSTS
Cytogenetic Map17B1UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001278601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_013693 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB039224 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB039226 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB039227 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB039228 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB039229 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB039230 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB039231 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB039232 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB062426 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB185894 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB185895 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB185896 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF109719 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK153319 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK153800 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK154223 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK155964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY423855 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC117057 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC137720 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY167004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466666 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR974444 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU407309 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU466548 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D84196 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D84199 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GQ917239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L22359 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L22360 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L22361 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L22362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L22363 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L22364 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L22365 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  LC636331 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  LN874395 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M11731 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M13049 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M20155 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M38296 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MW116778 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MW116779 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MW116780 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MW116781 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MW116782 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U06950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U68414 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X02611 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y00467 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000025263   ⟹   ENSMUSP00000025263
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1735,418,357 - 35,420,983 (-)Ensembl
GRCm38.p6 Ensembl1735,199,381 - 35,202,007 (-)Ensembl
RefSeq Acc Id: ENSMUST00000167924   ⟹   ENSMUSP00000126122
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1735,418,483 - 35,420,980 (-)Ensembl
GRCm38.p6 Ensembl1735,199,507 - 35,202,004 (-)Ensembl
RefSeq Acc Id: NM_001278601   ⟹   NP_001265530
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391735,418,343 - 35,420,983 (-)NCBI
GRCm381735,199,367 - 35,202,007 (-)NCBI
Celera1738,296,067 - 38,298,710 (-)NCBI
Sequence:
RefSeq Acc Id: NM_013693   ⟹   NP_038721
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391735,418,343 - 35,420,983 (-)NCBI
GRCm381735,199,367 - 35,202,007 (-)NCBI
MGSCv371735,336,335 - 35,338,941 (-)RGD
Celera1738,296,067 - 38,298,710 (-)NCBI
cM Map17 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_001265530 (Get FASTA)   NCBI Sequence Viewer  
  NP_038721 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA18594 (Get FASTA)   NCBI Sequence Viewer  
  AAA40457 (Get FASTA)   NCBI Sequence Viewer  
  AAA40458 (Get FASTA)   NCBI Sequence Viewer  
  AAA40459 (Get FASTA)   NCBI Sequence Viewer  
  AAA40462 (Get FASTA)   NCBI Sequence Viewer  
  AAB65593 (Get FASTA)   NCBI Sequence Viewer  
  AAC82484 (Get FASTA)   NCBI Sequence Viewer  
  AAI17058 (Get FASTA)   NCBI Sequence Viewer  
  AAI37721 (Get FASTA)   NCBI Sequence Viewer  
  AAR00346 (Get FASTA)   NCBI Sequence Viewer  
  BAA19512 (Get FASTA)   NCBI Sequence Viewer  
  BAA19513 (Get FASTA)   NCBI Sequence Viewer  
  BAB68748 (Get FASTA)   NCBI Sequence Viewer  
  BAB68750 (Get FASTA)   NCBI Sequence Viewer  
  BAB68751 (Get FASTA)   NCBI Sequence Viewer  
  BAB68752 (Get FASTA)   NCBI Sequence Viewer  
  BAB68753 (Get FASTA)   NCBI Sequence Viewer  
  BAB68754 (Get FASTA)   NCBI Sequence Viewer  
  BAB68755 (Get FASTA)   NCBI Sequence Viewer  
  BAB68756 (Get FASTA)   NCBI Sequence Viewer  
  BAB78397 (Get FASTA)   NCBI Sequence Viewer  
  BAE31899 (Get FASTA)   NCBI Sequence Viewer  
  BAE32187 (Get FASTA)   NCBI Sequence Viewer  
  BAE32445 (Get FASTA)   NCBI Sequence Viewer  
  BAE33525 (Get FASTA)   NCBI Sequence Viewer  
  BAF02298 (Get FASTA)   NCBI Sequence Viewer  
  BAF02299 (Get FASTA)   NCBI Sequence Viewer  
  BAF02300 (Get FASTA)   NCBI Sequence Viewer  
  CAA26457 (Get FASTA)   NCBI Sequence Viewer  
  CAA68530 (Get FASTA)   NCBI Sequence Viewer  
  CTQ86160 (Get FASTA)   NCBI Sequence Viewer  
  EDL26631 (Get FASTA)   NCBI Sequence Viewer  
  EDL26632 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000025263
  ENSMUSP00000025263.9
  ENSMUSP00000126122
  ENSMUSP00000126122.2
GenBank Protein P06804 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_038721   ⟸   NM_013693
- Peptide Label: isoform 1
- UniProtKB: Q62326 (UniProtKB/Swiss-Prot),   O35853 (UniProtKB/Swiss-Prot),   Q91VF3 (UniProtKB/Swiss-Prot),   P06804 (UniProtKB/Swiss-Prot),   Q3U593 (UniProtKB/TrEMBL),   Q3U4I6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001265530   ⟸   NM_001278601
- Peptide Label: isoform 2
- UniProtKB: A0A0R4J210 (UniProtKB/TrEMBL),   Q3U4I6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000126122   ⟸   ENSMUST00000167924
RefSeq Acc Id: ENSMUSP00000025263   ⟸   ENSMUST00000025263
Protein Domains
TNF family profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P06804-F1-model_v2 AlphaFold P06804 1-235 view protein structure

Promoters
RGD ID:13675844
Promoter ID:EPDNEW_M22071
Type:multiple initiation site
Name:Tnf_1
Description:Mus musculus tumor necrosis factor , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381735,202,007 - 35,202,067EPDNEW
RGD ID:6828817
Promoter ID:MM_KWN:23288
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Liver,   Lung,   Spleen
Transcripts:ENSMUST00000025263,   UC008CGS.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361735,338,676 - 35,339,822 (-)MPROMDB
RGD ID:6850154
Promoter ID:EP36013
Type:single initiation site
Name:MM_TNFA
Description:Tumor necrosis factor-alpha, TNF or TNFA gene.
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Notes:homology_group=Homology group 211; Mammalian tumor necrosis factor alpha
Experiment Methods:Sequencing of a full-length cDNA; Nuclease protection with homologous sequence ladder; experiments; performed with closely related gene
Regulation:monocytes, macrophages ( (induced by or strongly expressed in) LPS); T (repressed by or weakly expressed in) cells
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv371735,338,952 - 35,339,012EPD
MGSCv361735,338,952 - 35,339,012EPD

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:104798 AgrOrtholog
Ensembl Genes ENSMUSG00000024401 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000025263 ENTREZGENE
  ENSMUST00000025263.15 UniProtKB/Swiss-Prot
  ENSMUST00000167924 ENTREZGENE
  ENSMUST00000167924.2 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro TNF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TNF_alpha UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TNF_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TNF_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tumour_necrosis_fac-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:21926 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:104798 ENTREZGENE
NCBI Gene 21926 ENTREZGENE
PANTHER PTHR11471:SF23 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TUMOR NECROSIS FACTOR FAMILY MEMBER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam TNF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB TNF RGD
PhenoGen Tnf PhenoGen
PRINTS TNECROSISFCT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TNFALPHA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE TNF_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TNF_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART TNF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF49842 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0R4J210 ENTREZGENE, UniProtKB/TrEMBL
  A0A0U5J4W4_MOUSE UniProtKB/TrEMBL
  O35853 ENTREZGENE
  P06804 ENTREZGENE
  Q3U4I6 ENTREZGENE, UniProtKB/TrEMBL
  Q3U593 ENTREZGENE, UniProtKB/TrEMBL
  Q62326 ENTREZGENE
  Q6TDG3_MOUSE UniProtKB/TrEMBL
  Q91VF3 ENTREZGENE
  TNFA_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary O35853 UniProtKB/Swiss-Prot
  Q62326 UniProtKB/Swiss-Prot
  Q91VF3 UniProtKB/Swiss-Prot