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GENE - TERM ANNOTATION REPORT

RGD ID: 14181661
Species: Sus scrofa
RGD Object: Gene
Symbol: TNF
Name: tumor necrosis factor
Acc ID: DOID:13141
Term: uveitis
Definition: An uveal disease is characterized by inflammation of any of the layers of the uvea of the eye, which includes the iris, ciliary body, and choroid. (DO)
Definition Source(s): https://www.mayoclinic.org/diseases-conditions/uveitis/symptoms-causes/syc-20378734 "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
TNF ISOTNF (Homo sapiens)9068941RGD PMID:1318867 PMID:20673052 REF_RGD_ID:7394761 REF_RGD_ID:7401178
TNF ISOTNF (Homo sapiens)9068941RGDassociated with Behcet Syndrome; protein:increased expression:serum:PMID:15209464 REF_RGD_ID:7387294
TNF ISOTnf (Rattus norvegicus)9068941RGD PMID:8125721 REF_RGD_ID:7401166
TNFdisease_progressionISOTNF (Homo sapiens)9068941RGDprotein:increased expression:serum,Aqueous Humor:PMID:11586057 REF_RGD_ID:7394806
TNFtreatmentISOTnf (Rattus norvegicus)9068941RGD PMID:19440225 REF_RGD_ID:13825264
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