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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 14181661
Species: Sus scrofa
RGD Object: Gene
Symbol: TNF
Name: tumor necrosis factor
Acc ID: CHEBI:10022
Term: deoxynivalenol
Definition: A trichothecene mycotoxin produced by Fusarium to which wheat, barley, maize (corn) and their products are susceptible to contamination.
Chemical ID: MESH:C007262
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
TNFincreases expressionEXP 6480464CTDdeoxynivalenol results in increased expression of TNF mRNA

PMID:19027837 PMID:23326479 PMID:23688591 PMID:24394488
TNFmultiple interactionsEXP 6480464CTD[deoxynivalenol co-treated with fumonisin B1] results in increased expression of TNF mRNA [deoxynivalenol co-treated with Lipopolysaccharides co-treated with fumonisin B1] results in increased expression of TNF mRNA [deoxynivalenol co-treated with Lipopolysaccharides co-treated with fumonisin B1] results in increased expression of TNF protein [deoxynivalenol co-treated with nivalenol co-treated with fumonisin B1] results in increased expression of TNF mRNA [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of TNF mRNA [deoxynivalenol co-treated with nivalenol co-treated with Zearalenone] results in increased expression of TNF mRNA [deoxynivalenol co-treated with nivalenol] results in increased expression of TNF mRNA [deoxynivalenol co-treated with Zearalenone co-treated with fumonisin B1] results in increased expression of TNF mRNA [deoxynivalenol co-treated with Zearalenone] results in increased expression of TNF mRNA [Zearalenone co-treated with deoxynivalenol] results in decreased expression of TNF mRNA deoxynivalenol promotes the reaction [lipopolysaccharide Escherichia coli O111 B4 results in increased expression of TNF mRNA] deoxynivalenol promotes the reaction [lipopolysaccharide Escherichia coli O111 B4 results in increased expression of TNF protein] lipopolysaccharide Escherichia coli O111 B4 promotes the reaction [deoxynivalenol results in increased expression of TNF mRNA]

PMID:18296887 PMID:19027837 PMID:19607891 PMID:23688591 PMID:30708112
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