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GENE - TERM ANNOTATION REPORT

RGD ID: 14181661
Species: Sus scrofa
RGD Object: Gene
Symbol: TNF
Name: tumor necrosis factor
Acc ID: DOID:9002211
Term: Hyperalgesia
Definition: An increased sensation of pain or discomfort produced by mimimally noxious stimuli due to damage to soft tissue containing NOCICEPTORS or injury to a peripheral nerve.
Definition Source(s): MESH:D006930
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
TNF ISOTnf (Mus musculus)9068941RGD PMID:10825476 PMID:18790011 REF_RGD_ID:7394737 REF_RGD_ID:7394741
TNF ISOTnf (Mus musculus)9068941RGDassociated with Diabetic Neuropathies;PMID:21104419 REF_RGD_ID:7401179
TNF ISOTnf (Mus musculus)9068941RGDmRNA,protein:increased expression:spinal cord:PMID:18790011 REF_RGD_ID:7394737
TNF ISOTnf (Rattus norvegicus)9068941RGD PMID:16675114 PMID:17304130 PMID:17459378 REF_RGD_ID:7387300 REF_RGD_ID:7387302 REF_RGD_ID:7394757
TNF ISOTnf (Rattus norvegicus)9068941RGDprotein:increased expression:lumbar vertebra:PMID:16675114 REF_RGD_ID:7387300
TNF ISOTNF (Homo sapiens)9068941CTDCTD Direct Evidence: marker/mechanismPMID:10401557 PMID:12727271 PMID:16472913 PMID:17320857 PMID:18463260 PMID:18582539 PMID:20383154 PMID:26141506 PMID:27093858 PMID:7582491 PMID:7881729
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