GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tnf | multiple interactions | EXP | | 6480464 | CTD | Cilostazol inhibits the reaction [Cyclophosphamide results in increased expression of TNF mRNA] | PMID:32456565 | Tnf | decreases expression | ISO | Tnf (Mus musculus) | 6480464 | CTD | cilostazol results in decreased expression of TNF protein | PMID:20131233 | Tnf | decreases response to substance | ISO | TNF (Homo sapiens) | 6480464 | CTD | cilostazol results in decreased susceptibility to TNF protein | PMID:21660147 | Tnf | multiple interactions | ISO | Tnf (Mus musculus) | 6480464 | CTD | cilostazol inhibits the reaction [4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone results in decreased expression of TNF protein]; cilostazol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] | PMID:15169552 PMID:21256160 | Tnf | multiple interactions | ISO | TNF (Homo sapiens) | 6480464 | CTD | [Cilostazol co-treated with Probucol] inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Cilostazol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Cilostazol inhibits the reaction [TNF protein results in increased expression of CCL2]; Cilostazol inhibits the reaction [TNF protein results in increased expression of VCAM1]; Cilostazol inhibits the reaction [TNF results in decreased phosphorylation of AKT1 protein]; Cilostazol inhibits the reaction [TNF results in decreased phosphorylation of CREB1 protein]; Cilostazol inhibits the reaction [TNF results in increased phosphorylation of PTEN protein]; Cilostazol promotes the reaction [Probucol inhibits the reaction [TNF protein results in increased expression of CCL2]]; Cilostazol promotes the reaction [Probucol inhibits the reaction [TNF protein results in increased expression of VCAM1]]; HMOX1 mutant form inhibits the reaction [Cilostazol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]]; iberiotoxin inhibits the reaction [Cilostazol inhibits the reaction [TNF results in decreased phosphorylation of AKT1 protein]]; iberiotoxin inhibits the reaction [Cilostazol inhibits the reaction [TNF results in decreased phosphorylation of CREB1 protein]]; iberiotoxin inhibits the reaction [Cilostazol inhibits the reaction [TNF results in increased phosphorylation of PTEN protein]]; paxilline inhibits the reaction [Cilostazol inhibits the reaction [TNF results in decreased phosphorylation of AKT1 protein]]; paxilline inhibits the reaction [Cilostazol inhibits the reaction [TNF results in decreased phosphorylation of CREB1 protein]]; paxilline inhibits the reaction [Cilostazol inhibits the reaction [TNF results in increased phosphorylation of PTEN protein]]; Probucol promotes the reaction [Cilostazol inhibits the reaction [TNF protein results in increased expression of CCL2]]; Probucol promotes the reaction [Cilostazol inhibits the reaction [TNF protein results in increased expression of VCAM1]]; PTEN affects the reaction [Cilostazol inhibits the reaction [TNF results in decreased phosphorylation of AKT1 protein]]; PTEN affects the reaction [Cilostazol inhibits the reaction [TNF results in decreased phosphorylation of CREB1 protein]]; PTEN affects the reaction [iberiotoxin inhibits the reaction [Cilostazol inhibits the reaction [TNF results in decreased phosphorylation of AKT1 protein]]]; PTEN affects the reaction [iberiotoxin inhibits the reaction [Cilostazol inhibits the reaction [TNF results in decreased phosphorylation of CREB1 protein]]]; zinc protoporphyrin inhibits the reaction [Cilostazol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]]; zinc protoporphyrin inhibits the reaction [Cilostazol results in decreased susceptibility to TNF protein] | PMID:12807996 PMID:19967051 PMID:20131233 PMID:21660147 | | ||||||||||||||||||||||
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