Aia1 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Aia1 (Adjuvant induced arthritis QTL 1) Rattus norvegicus

Symbol: Aia1
Name: Adjuvant induced arthritis QTL 1
RGD ID: 61472
Trait: joint integrity trait   (VT:0010548)    
Measurement Type: joint inflammation composite score   (CMO:0000919)    
LOD Score: 18.0
P Value: 0.001
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2202,646,395 - 4,597,031RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0203,151,815 - 6,896,013RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0205,249,981 - 8,621,883RGDRnor5.0
RGSC_v3.4202,790,511 - 4,530,895RGDRGSC3.4
RGSC_v3.1202,790,738 - 4,531,120RGD
Cross Type: F2
Strains Crossed: DA F344/NRrrc 
JBrowse: View Region in Genome Browser (JBrowse)
Model



Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain
DA  (IEA)
F344/NRrrc  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Identification of four new quantitative trait loci regulating arthritis severity and one new quantitative trait locus regulating autoantibody production in rats with collagen-induced arthritis. Griffiths MM, etal., Arthritis Rheum 2000 Jun;43(6):1278-89
2. Quest for arthritis-causative genetic factors in the rat. Joe B Physiol Genomics. 2006 Oct 3;27(1):1-11. Epub 2006 Jun 27.
3. Localization of quantitative trait loci regulating adjuvant-induced arthritis in rats: evidence for genetic factors common to multiple autoimmune diseases. Kawahito Y, etal., J Immunol 1998 Oct 15;161(8):4411-9
4. Linkage mapping of the Fos cellular oncogene (Fos) to rat chromosome 6 and its possible role in the regulation of compensatory renal growth. Pravenec M, etal., Folia Biol (Praha) 1998;44(5):151-3.
5. The complexity in hunting for candidate genes within QTL that determine susceptibility to arthritis in rats. Xiong Q, etal., Crit Rev Immunol. 2008;28(2):127-57.
6. Genetic and molecular basis of quantitative trait loci of arthritis in rat: genes and polymorphisms. Xiong Q, etal., J Immunol. 2008 Jul 15;181(2):859-64.
Related QTLs

Related QTL Description Reference
Oia1 interacts with RGD:61035
Pia1 interacts with RGD:61035
Coreg1 maps to same region RGD:69708
Cia1 interacts with RGD:61035
Ciaa1 maps to same region RGD:61066


Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
41288091RT1-O1l1RT1 class Ib, locus O1 like 12026240732658023Rat
1595920RT1-S2RT1 class Ib, locus S22026502332651654Rat
1595735Rps2-ps1ribosomal protein S2, pseudogene 12026539582654686Rat
3501RT1-O1RT1 class Ib, locus O12026551162657520Rat
1598370RT1-N3RT1 class Ib, locus N32026591322665536Rat
735037RT1-S3RT1 class Ib, locus S32026706542675411Rat
1598233RT1-T24-4RT1 class I, locus T24, gene 42026845152747878Rat
727839LOC360231MHC class I RT1.O type 149 processed pseudogene2026845592743176Rat
15944252361ex4-5class I gene fragment 23612026939752694324Rat
1594426Rpl41-ps1ribosomal protein L41, pseudogene 12027044562704840Rat
41100225LOC120098968uncharacterized LOC1200989682027081982732345Rat
1624211RT1-T24-3RT1 class I, locus T24, gene 32027182102730604Rat
15944272331ex4-5class I gene fragment 23312027242342724758Rat
1303033RT1-T24-2RT1 class I, locus T24, gene 22027344152738899Rat
15944282310ex4-5class I gene fragment 23102027453912745740Rat
1359499RT1-T24-1RT1 class I, locus T24, gene 12027614952774871Rat
1303051Gnl1G protein nucleolar 12027831302792115Rat
1303270Prr3proline rich 32027928682799865Rat
620286Abcf1ATP binding cassette subfamily F member 12028025192815433Rat
2325510Mir877microRNA 8772028114762811560Rat
620079Ppp1r10protein phosphatase 1, regulatory subunit 102028229952838125Rat
1302998Mrps18bmitochondrial ribosomal protein S18B2028381742844260Rat
1303066Atat1alpha tubulin acetyltransferase 12028445952857809Rat
1302996C20h6orf136similar to human chromosome 6 open reading frame 1362028578402861952Rat
1302963Dhx16DEAH-box helicase 162028620002874991Rat
1309543Ppp1r18protein phosphatase 1, regulatory subunit 182028775672887526Rat
7489035Mir6328microRNA 63282028853002885396Rat
1302966Nrmnurim2028883212892804Rat
1559468Mdc1mediator of DNA damage checkpoint 12028936932912394Rat
628596Tubb5tubulin, beta 5 class I2029127792916928Rat
70991Flot1flotillin 12029178642927993Rat
1303321Ier3immediate early response 32029283782929582Rat
7678499LOC102553505uncharacterized LOC1025535052029620292972097Rat
2313830Cb707485hypothetical LOC1003107832030213903024364Rat
2252Ddr1discoidin domain receptor tyrosine kinase 12030424943064442Rat
1303309Gtf2h4general transcription factor 2H subunit 42030713283076990Rat
1303122Vars2valyl-tRNA synthetase 2, mitochondrial2030771323087994Rat
1303180Sfta2surfactant associated 22030935693094299Rat
1303125Mucl3mucin like 32031006523108569Rat
1302953CB741658CB741658 gene2031190503122302Rat
41289706LOC120098824uncharacterized LOC1200988242031507553162973Rat
2324335Mt2-ps1metallothionein 2, pseudogene 12031590373159409Rat
1562885C20h6orf15similar to human chromosome 6 open reading frame 152031723303173886Rat
41360741LOC120098827uncharacterized LOC1200988272031788873183700Rat
1598543Cdsncorneodesmosin2031794323184252Rat
1594430Rpl22-ps1ribosomal protein L22, pseudogene 12031901483190745Rat
1591981Psors1c2psoriasis susceptibility 1 candidate 22032021783203599Rat
1302992Cchcr1coiled-coil alpha-helical rod protein 12032056753218437Rat
1302974Tcf19transcription factor 192032187563222861Rat
1359491Pou5f1POU class 5 homeobox 12032231283227891Rat
1359403RT1-CE16RT1 class I, locus CE162032571093260747Rat
11357632LOC108353253uncharacterized LOC1083532532032606973290136Rat
1594403Cdk2ap1-ps8Cdk2ap1-ps8 pseudogene2032679053268051Rat
1359630RT1-CE15RT1 class I, locus CE152032755753279074Rat
41066463LOC120098828uncharacterized LOC1200988282032790753280604Rat
1594404LOC224733l-9LOC224733l-9 pseudogene2032824953282800Rat
1359342RT1-CE14RT1 class I, locus CE142032966543300795Rat
1359196RT1-CE13RT1 class I, locus CE132033148303318106Rat
41203922LOC120098829uncharacterized LOC1200988292033180513324485Rat
1594406Cdk2ap1-ps6Cdk2ap1-ps6 pseudogene2033261663327363Rat
1594407Sacm2l-ps7Sacm2l-ps7 pseudogene2033307463331375Rat
1594408Sacm2l-ps6Sacm2l-ps6 pseudogene2033314613331539Rat
1594409Sacm2l-ps5Sacm2l-ps5 pseudogene2033317283332881Rat
1359103RT1-CE12RT1 class I, locus CE122033389073342547Rat
1359483RT1-CE11RT1 class I, locus CE112033553933358520Rat
41049112LOC120098832uncharacterized LOC1200988322033588293382786Rat
1594410LOC224733l-8LOC224733l-8 pseudogene2033619303362233Rat
1594411Cdk2ap1-ps5Cdk2ap1-ps5 pseudogene2033690473369193Rat
1359292RT1-CE10RT1 class I, locus CE102033772843380301Rat
1594412LOC224733l-7LOC224733l-7 pseudogene2033831633383468Rat
1595868RT1-CE5RT1 class I, locus CE52034034183479476Rat
1594413RT1-CE9-ps1RT1 class I, locus CE9, pseudogene 12034036553406844Rat
1594414RT1-CE8-ps1RT1 class I, locus CE8, pseudogene 12034182653421623Rat
1594416Cdk2ap1-ps4Cdk2ap1-ps4 pseudogene2034289273430126Rat
1598234RT1-CE4RT1 class I, locus CE42034315093504535Rat
1595786RT1-CE7RT1 class I, locus CE72034342053437152Rat
41176734LOC120098833uncharacterized LOC1200988332034373733439343Rat
1594417LOC224733l-5LOC224733l-5 pseudogene2034397233440020Rat
1303017RT1-CE6RT1 class I, locus CE62034609793461929Rat
1594418Sacm2l-ps4Sacm2l-ps4 pseudogene2034680353469175Rat
1594419LOC224733l-4LOC224733l-4 pseudogene2034828943483196Rat
1594420Cdk2ap1-ps3Cdk2ap1-ps3 pseudogene2034930953493240Rat
1594421LOC224733l-3LOC224733l-3 pseudogene2035079743508279Rat
1598231RT1-CE3RT1 class I, locus CE32035166473520938Rat
1594422Cdk2ap1-ps2Cdk2ap1-ps2 pseudogene2035335093534644Rat
1598235RT1-CE2RT1 class I, locus CE22035384523541841Rat
70923Ddx39bDExD-box helicase 39B2035477023585064Rat
1594423Sacm2l-ps3Sacm2l-ps3 pseudogene2035484813548940Rat
1595869RT1-CE1RT1 class I, locus12035557793559487Rat
41374192Snord83Small nucleolar RNA SNORD832035787663578840Rat
41079206LOC120099056small nucleolar RNA SNORD832035839713584049Rat
1303186Atp6v1g2ATPase H+ transporting V1 subunit G22035876813591309Rat
1303310Nfkbil1NFKB inhibitor like 12035899743608348Rat
3020Ltalymphotoxin alpha2036188533621324Rat
3876Tnftumor necrosis factor2036220113624629Rat
1303162Ltblymphotoxin beta2036275363629381Rat
620077Lst1leukocyte specific transcript 12036346803639731Rat
727881Ncr3natural cytotoxicity triggering receptor 32036372423643748Rat
61924Aif1allograft inflammatory factor 12036467843652670Rat
1303199E230034O05RikE230034O05Rik gene2036563063658463Rat
1303025Prrc2aproline-rich coiled-coil 2A2036583913674143Rat
41318103Snora38small nucleolar RNA, H/ACA box 382036609003661033Rat
71064Bag6BAG cochaperone 62036759383690414Rat
620773Apomapolipoprotein M2036909503693550Rat
1303038G4G4 protein2036936913696194Rat
1303304Gpank1G patch domain and ankyrin repeats 12036976413700814Rat
619978Csnk2bcasein kinase 2 beta2037003633705331Rat
1303101Ly6g5blymphocyte antigen 6 family member G5B2037054643707830Rat
735180Ly6g5clymphocyte antigen 6 family member G5C2037094263713940Rat
1303164Abhd16aabhydrolase domain containing 16A, phospholipase2037190893733952Rat
1594424Rps25-ps2ribosomal protein S25, pseudogene 22037353473735801Rat
1303333Ly6g6flymphocyte antigen 6 family member G6F2037374593742327Rat
1303064Ly6g6dlymphocyte antigen 6 family member G6D2037419733752378Rat
1303112Ly6g6elymphocyte antigen 6 family member G6E2037449993749867Rat
1302999Ly6g6clymphocyte antigen 6 family member G6C2037536323757205Rat
1303269Mpig6bmegakaryocyte and platelet inhibitory receptor G6b2037573963761024Rat
1302955Ddah2DDAH family member 2, ADMA-independent2037614603764718Rat
1303043Clic1chloride intracellular channel 12037648673773711Rat
1303008Msh5mutS homolog 52037738673793337Rat
41396061LOC120099048U6 spliceosomal RNA2037745723774677Rat
1359359Sapcd1suppressor APC domain containing 12037939803795767Rat
1303137Vwa7von Willebrand factor A domain containing 72037949913805646Rat
3950Vars1valyl-tRNA synthetase 12038057743820468Rat
11436027LOC108349032uncharacterized LOC1083490322038206733830868Rat
1590214Rpl13-ps1ribosomal protein L13, pseudogene 12038394603839702Rat
1598536Lsm2LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated2038434673847217Rat
1595925Hspa1lheat shock protein family A (Hsp70) member 1 like2038488433855571Rat
2840Hspa1bheat shock protein family A (Hsp70) member 1B2038551043859148Rat
1593284Hspa1aheat shock protein family A (Hsp70) member 1A2038707653873221Rat
7707260LOC102549726uncharacterized LOC1025497262038765633879281Rat
41104675Snord48small nucleolar RNA, C/D box 482038772833877346Rat
41062511Snord52small nucleolar RNA, C/D box 522038784123878477Rat
3163Neu1neuraminidase 12038974803901745Rat
41072487LOC120098979uncharacterized LOC1200989792039009763906605Rat
1303167Slc44a4solute carrier family 44, member 42039030993919215Rat
1302972Ehmt2euchromatic histone lysine methyltransferase 22039196233936751Rat
1302958Zbtb12zinc finger and BTB domain containing 122039376683940514Rat
7661101LOC102553878uncharacterized LOC1025538782039398263944890Rat
2231C2complement C22039514743970376Rat
2204Cfbcomplement factor B2039706433976510Rat
1303325Nelfenegative elongation factor complex member E2039765123982389Rat
1303059Skic2SKI2 subunit of superkiller complex2039824943993261Rat
1303267Dxodecapping exoribonuclease2039933223995484Rat
1359601Stk19serine/threonine kinase 192039955904005117Rat
620005C4acomplement C4A2040057314020083Rat
2461Cyp21a1cytochrome P450, family 21, subfamily a, polypeptide 12040202174026923Rat
3887Tnxa-ps1tenascin XA, pseudogene 12040264714027826Rat
40991350LOC120098978uncharacterized LOC1200989782040846124087472Rat
1303317Atf6bactivating transcription factor 6 beta2040909214098920Rat
1303227FkbplFKBP prolyl isomerase like2040998454101315Rat
620375Ppt2palmitoyl-protein thioesterase 22041125204132774Rat
1359348Prrt1proline-rich transmembrane protein 12041179574121643Rat
1549706Egfl8EGF-like-domain, multiple 82041329304136024Rat
1303287Agpat11-acylglycerol-3-phosphate O-acyltransferase 12041359554144880Rat
1588458Rnf5ring finger protein 52041455394147985Rat
69258Ageradvanced glycosylation end product-specific receptor2041481504151361Rat
1303084Pbx2PBX homeobox 22041515004156425Rat
1303014Gpsm3G-protein signaling modulator 32041571234158984Rat
1303282Notch4notch receptor 42041603624184466Rat
1588459Stk19-psserine/threonine kinase 19 pseudogene2041941714196677Rat
1591983C4bcomplement C4B2041973714211684Rat
1303332Cyp21a1-pscytochrome P450, family 21, subfamily a, polypeptide 1, pseudogene2042156374231737Rat
1624210Btnl4butyrophilin-like 42042313504244825Rat
1303010Btnl8butyrophilin-like 82042648404280876Rat
1303124Btnl7butyrophilin-like 72043010784313522Rat
1588460Btnl6-ps1butyrophilin-like 6, pseudogene 12043369024344877Rat
1598537Btnl5butyrophilin-like 52043667804376385Rat
1598538Btn3a2butyrophilin, subfamily 3, member A22043982544405681Rat
1597063Tsbp1testis expressed basic protein 12044100024467284Rat
1303262Btnl3butyrophilin-like 32044740564489024Rat
11477629LOC108349035uncharacterized LOC1083490352044758274479937Rat
620731Btnl2butyrophilin-like 22044901694504002Rat
1593283RT1-DaRT1 class II, locus Da2045134644518457Rat
1595922RT1-Db2RT1 class II, locus Db22045207234539724Rat
1303212Arrb2-psarrestin, beta 2, pseudogene2045238974524874Rat
1593282RT1-Db1RT1 class II, locus Db12045486644558237Rat
1595867RT1-BaRT1 class II, locus Ba2045751344579727Rat
3469RT1-BbRT1 class II, locus Bb2045965584602201Rat
1594405Cdk2ap1-ps7Cdk2ap1-ps7 pseudogene2032896063289752Rat
1594415LOC224733l-6LOC224733l-6 pseudogene2034236423423957Rat

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
11206D20Arb21642026463952646556Ratregion
11206D20Arb21642026664952666654Ratregion
11207D20Wox52592026588952659158Ratregion
11208D20Mgh32462034177563417890Ratregion
11208D20Mgh32462035168013516931Ratregion
11209D20Wox42412034177613417890Ratregion
11209D20Wox42412035168063516931Ratregion
34749D20UW11522036216493621791Ratregion
34749D20UW11522036216493621791Ratregion
11428D20Wox31152036216563621771Ratregion
11428D20Wox31152036216563621771Ratregion
35593D20Rat171722033967533396913Ratregion
38826D20Rat421412044596984459841Ratregion
41562D20Rat461682028925972892739Ratregion
43140D20Rat712322028836772883902Ratregion
45668D20Got21272030900783090202Ratregion
45669D20Got41742037758303776003Ratregion
66471D20Uia11402044487204448860Ratregion
1576378D20Ztm11742036215993621773Ratregion
1576378D20Ztm11742036215993621773Ratregion
1630310D20Got1021622041463734146535Ratregion
1639768D20Wox122032038688473869052Ratregion
1633553D20Wox152026464072646531Ratregion
1633553D20Wox152026665072666629Ratregion
2303197D20Yum621502041275334127683Ratregion
2303199D20Yum581702039985813998751Ratregion
2303203D20Yum512212037340773734302Ratregion
2303205D20Yum711522044233414423493Ratregion
2303207D20Yum571792039658813966060Ratregion
2303211D20Yum611662040994114099577Ratregion
2303213D20Yum361562029236622924126Ratregion
2303213D20Yum361562029239702924126Ratregion
2303215D20Yum651062042423524242458Ratregion
2303219D20Yum551612038975213897682Ratregion
2303223D20Yum671792042743464274525Ratregion
2303223D20Yum671792042770004277180Ratregion
2303225D20Yum631572041714334171590Ratregion
2303233D20Yum501552037025943702749Ratregion
2303235D20Yum371862029776932977879Ratregion
2303237D20Yum842392026612162661459Ratregion
2303239D20Yum591742040310684031242Ratregion
2303247D20Yum311792026884992688678Ratregion
2303249D20Yum641542042014954201649Ratregion
2303251D20Yum381512030050823005233Ratregion
2303253D20Yum602040571584057419Ratregion
2303253D20Yum602040572774057419Ratregion
2303255D20Yum411672031366703136837Ratregion
2303265D20Yum472272035761103576337Ratregion
2303267D20Yum402372031078673108104Ratregion
2303269D20Yum741622045763954576557Ratregion
2303271D20Yum422452031660293166274Ratregion
2303273D20Yum702272044095874409812Ratregion
2303275D20Yum491852036473353647520Ratregion
2303281D20Yum341662028072422807408Ratregion
2303287D20Yum481922036268273627019Ratregion
2303287D20Yum481922036268273627019Ratregion
2303289D20Yum522232037500983750321Ratregion
2303293D20Yum331632027664602766623Ratregion
2303299D20Yum531972038366033836800Ratregion
2303301D20Yum391672030573303057497Ratregion
2303305D20Yum691892043432284343417Ratregion
2303307D20Yum731142045224654522579Ratregion
2303307D20Yum731142045224654522797Ratregion
2303309D20Yum721692044931384493307Ratregion
7206058Tubb52012029159292916130Ratregion
7206082Pou5f13472032245213224868Ratregion
5039134RH1275322032033293163329519Ratregion
5031244PMC112151P14702036230593623529Ratregion
5031244PMC112151P14702036230593623529Ratregion
5031256PMC116546P11712036235303623701Ratregion
5031256PMC116546P11712036235303623701Ratregion
5025988RH1304731512045183044518455Ratregion
5028591AI3260742072037195393719746Ratregion
5034400BE1170581502028555672855717Ratregion
5034450AA9003791862036763863676977Ratregion
5034480BG3725722062037926423793155Ratregion
5034660BF3908041852041366264136811Ratregion
5026672RH1330972142045959994596213Ratregion
5029529Bat1_microsatellite1412035727293572876Ratregion
5032479D17Ertd710e2252039196383919863Ratregion
5029743BI2844841902027253132725503Ratregion
5027519AI255840982039763003976398Ratregion
5030335AI1132372152036204783620693Ratregion
5030335AI1132372152036204783620693Ratregion
5025356RH1279991942038435753843769Ratregion
5033427RH1387921462040999164100062Ratregion
5033455RH1388961202037275253727645Ratregion
5030981BF4053041642026775592677730Ratregion
5031159BI2987341542026850512685205Ratregion
5031159BI2987341542027619432762097Ratregion
5051911RH947291752036241973624375Ratregion
5051911RH947291752036241973624375Ratregion
5052061RH948173302036226943623024Ratregion
5052061RH948173302036226943623024Ratregion
5051276RH1345401812038057873806488Ratregion
5051913RH947301452036216583621793Ratregion
5051913RH947301452036216583621793Ratregion
5055647RH1439211712034372183437388Ratregion
5055647RH1439211712035045463504716Ratregion
5058600BI2843062062041363854136591Ratregion
5056361RH1443342602035726013572969Ratregion
5052549AI450394942028778142877908Ratregion
5053205RH1425141002037813183781418Ratregion
5058492AW5238911012026519642652065Ratregion
5049826RH1337042142037191303719391Ratregion
5049906RH1337501912041477934147984Ratregion
5051715RH94616902040265094026599Ratregion
5041592RH1289461852038728853873070Ratregion
5041828RH1290821692029179092918078Ratregion
5046034RH1315202132027253662725579Ratregion
5046070RH1315411812031795223179703Ratregion
5041826RH1290811632037955793795742Ratregion
5044844RH1308362072039758063976336Ratregion
5048724RH1330692012041571914157392Ratregion
5046292RH1316681942028616622861856Ratregion
5046166RH1315962182038586363858854Ratregion
5047646RH1324471802032022713202451Ratregion
5046662RH1318821502041180034118153Ratregion
5046728RH1319201832029284482928631Ratregion
5049232RH1333611902028937742893964Ratregion
5048046RH1326772032032645543264757Ratregion
5048046RH1326772032032862503286454Ratregion
5048046RH1326772032033656903365894Ratregion
5048160RH1327432192027832782783761Ratregion
5046938RH13204102030936733094016Ratregion
5047106RH1321371972036977273697924Ratregion
5048384RH1328721962036384753638774Ratregion
5048576RH132983982026794032679501Ratregion
5049522RH1335291532045966024596755Ratregion
5049578RH13356102033108593311041Ratregion
5049578RH13356102033517533351935Ratregion
5040020RH1280431812028439812844162Ratregion
5040094RH1280852132037615043761717Ratregion
5039338RH1276491822029159642916146Ratregion
5039362RH1276622102036276373627847Ratregion
5039362RH1276622102036276373627847Ratregion
5040506RH1283231922039930113993203Ratregion
5040746RH1284591892028150852815274Ratregion
5040886RH1285402092032225723222781Ratregion
5043344RH1299721902037051103705300Ratregion
7192235D20Wox122042038688463869052Ratregion
5072778RH1370481862037051153705301Ratregion
5071940RH1353732052036519103652637Ratregion
5075544RH1386551712036243603624532Ratregion
5075544RH1386551712036243603624532Ratregion
5076798RH1393842042041357964136000Ratregion
5077722RH1399202152037608083761023Ratregion
5077736RH1399281872028890112889198Ratregion
5076288RH1390891892041613384161713Ratregion
5077998RH1400822102028101602810370Ratregion
5078186RH1401931942038976813897875Ratregion
5078264RH1402392162026648532665068Ratregion
5079300RH1409011512029178632918014Ratregion
5070974RH1348141842040265584026742Ratregion
5073334RH1373761502027998512800001Ratregion
5080420RH1415691802033285753328755Ratregion
5080420RH1415691802033285753328755Ratregion
5080420RH1415691802034315273431707Ratregion
5080420RH1415691802034315273431707Ratregion
5078672RH1404821322041323614132493Ratregion
5071400RH1350601922037451353745327Ratregion
5071660RH1352112142041361834136397Ratregion
5070201RH945301872038729183873105Ratregion
5060676BE0988921722036889303689103Ratregion
5065894AA9979091322036054513605583Ratregion
5065438BE1154942122040909764091188Ratregion
5066056BF4132352012040766934076894Ratregion
5061146BI2930461612032058003205961Ratregion
5062936BE1134821512041807094180860Ratregion
5066352PMC162222P19282041494854150413Ratregion
5064956BF4053322002041246334125169Ratregion
5082179BI2803351552033769373377091Ratregion
5087138BQ1943501662033815393381705Ratregion
5087138BQ1943501662034812553481421Ratregion
5082653BE1199391692041474994147668Ratregion
5087560PMC314357P14892038567183857207Ratregion
5087560PMC314357P14892038713103871800Ratregion
5087518PMC26794P36722036230583623730Ratregion
5087518PMC26794P36722036230583623730Ratregion
5084460AI1768041012041517444151845Ratregion
5084518AI1775601112034447173445771Ratregion
5084572AI0139412282040870984087326Ratregion
5081823BI2737851742029159642916138Ratregion
5084930AI2367511222028886512888773Ratregion
5085493AI5480471642028573642857528Ratregion
5081384AI4539612092041482174148512Ratregion
5081234RH1420432062036937483693954Ratregion
5085689BM3834641752034224963422670Ratregion
5507585Aif102036510593651818Ratregion
5503560UniSTS:46395902036228633623794Ratregion
5503560UniSTS:46395902036228633623794Ratregion
5503648UniSTS:4654675612041616764162237Ratregion
5504522PMC26660P43182029155792915897Ratregion
5505126H2-T234392026711772672392Ratregion
5505982UniSTS:4967391022029289402929042Ratregion
5506169UniSTS:4985067482037451873745935Ratregion
5506207Pou5f11772032233763223553Ratregion
5506231Clic11552037650253765180Ratregion
5499635MARC_5887-5888:991939775:17322041545724155304Ratregion
5499619MARC_3347-3348:991937077:11952037040623705128Ratregion
5500469RH12686602036798163680353Ratregion
5500507RH12688102035725693572935Ratregion
5503264UniSTS:2376302142040999204100134Ratregion
5501516RH358712462036778353678288Ratregion
5501760MARC_11957-11958:1003854518:15572036629913663548Ratregion
5501728UniSTS:2670092022029158572916059Ratregion
5502146MARC_5857-5858:997299374:102036512403651828Ratregion
5502124MARC_5045-5046:996690083:15632036726193673182Ratregion
5502132MARC_5411-5412:996690356:11742036763813676960Ratregion
5502299RH1243321632041324554132618Ratregion
Position Markers

Flank 1: (D20Arb2)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2202,666,495 - 2,666,654 (+)MAPPER
mRatBN7.2202,646,395 - 2,646,556 (+)MAPPER
Rnor_6.0203,151,815 - 3,151,975NCBI
Rnor_6.0203,171,911 - 3,172,069NCBI
Rnor_5.0205,270,077 - 5,270,235UniSTS
Rnor_5.0205,249,981 - 5,250,141UniSTS
RGSC_v3.4202,790,512 - 2,790,672UniSTS
RGSC_v3.4202,811,408 - 2,811,567RGD
RGSC_v3.4202,790,511 - 2,790,672RGD
RGSC_v3.4202,811,409 - 2,811,567UniSTS
RGSC_v3.1202,790,738 - 2,790,899RGD
Celera2076,870 - 77,030UniSTS
Celera2096,911 - 97,069UniSTS
SHRSP x BN Map200.0RGD
SHRSP x BN Map200.0UniSTS
FHH x ACI Map200.16RGD
Peak: (D20Wox3)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2203,621,656 - 3,621,771 (+)MAPPER
mRatBN7.2203,621,656 - 3,621,771 (-)MAPPER
Rnor_6.0205,192,240 - 5,192,354NCBI
Rnor_6.0204,855,475 - 4,855,589NCBI
Rnor_5.0206,935,875 - 6,935,989UniSTS
RGSC_v3.4203,660,646 - 3,660,760UniSTS
RGSC_v3.1203,660,872 - 3,660,987RGD
Celera204,403,718 - 4,403,832UniSTS
Cytogenetic Map20p12UniSTS
Flank 2: (D20Arb8)
Rat AssemblyChrPosition (strand)Source
Cytogenetic Map20 RGD


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2306850Pia40Pristane induced arthritis QTL 400.0001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)2015279595304575Rat
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124159021Rat
61448Ciaa1CIA Autoantibody QTL 1300.001blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)2026463954597031Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129191651Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129191651Rat
7175099Tcs2T cell selection QTL 2T cell selection trait (VT:0004917)expression2045040024693102Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578807Rat
61472Aia1Adjuvant induced arthritis QTL 1180.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)2026463954597031Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20153065546530655Rat
2317057Aia27Adjuvant induced arthritis QTL 272.83joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)20289259726381954Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600972Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20152784246527842Rat
1600382Edcs3Endometrial carcinoma susceptibility QTL33.50.003uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)20125159026Rat
1331772Cdexp2CD45RC expression in CD8 T cells QTL 25.7CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)20362164910078919Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129191651Rat
1300152Bp195Blood pressure QTL 1953.46arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2036216499243559Rat
724519Bp144Blood pressure QTL 1440.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2013624629Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129191651Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129191651Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
1598816Memor12Memory QTL 122.4exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)20260683647606836Rat
61432Cia1Collagen induced arthritis QTL 1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)20362165614101050Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600972Rat
737973Pia21Pristane induced arthritis QTL 214.8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)2036216564606812Rat


Additional Information

Database Acc Id Source(s)
NCBI Gene Aia1

RGD Curation Notes
Note Type Note Reference
qtl_gene 396 known and 70 novel genes were found in an analysis based on PubMed and OMIM data 2307198
qtl_gene whole genome analysis using PGMapper revealed Tnf, Mif, Tap2, Tap1, Hla-dma, Hla-dmb and Nfkbil1 as RA associated genes and Tnf, Mif, Tap2, Tap1, Hla-dma, Hla-dmb and Nfkbil1 as RA associated polymorphism either in coding or regulatory region 2300074