GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tnf | increases expression | EXP | | 6480464 | CTD | Fructose results in increased expression of TNF mRNA; Fructose results in increased expression of TNF protein | PMID:21704028 PMID:21708140 PMID:22426011 PMID:23968387 PMID:24508943 PMID:25108154 PMID:26358169 PMID:26713546 PMID:30480462 PMID:31661889 | Tnf | increases secretion | EXP | | 6480464 | CTD | Fructose results in increased secretion of TNF protein | PMID:25679220 | Tnf | multiple interactions | EXP | | 6480464 | CTD | 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [caryophyllene inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of TNF protein]]; [dapagliflozin co-treated with Atorvastatin] inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of TNF protein]; [Dietary Fats co-treated with Fructose] results in increased expression of TNF protein; [Fenofibrate co-treated with Resveratrol] inhibits the reaction [Fructose results in increased expression of and results in increased secretion of TNF protein]; [gadolinium chloride co-treated with Fructose co-treated with Copper deficiency] results in decreased expression of TNF mRNA; [Particulate Matter co-treated with Ozone] promotes the reaction [Fructose results in increased expression of TNF mRNA]; [Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of TNF protein; [Streptozocin co-treated with Fructose] results in increased expression of TNF protein; Acetates inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of TNF protein]; Allopurinol inhibits the reaction [Fructose results in increased expression of TNF protein]; bisphenol A promotes the reaction [Fructose results in increased expression of TNF protein]; caffeic acid phenethyl ester inhibits the reaction [Fructose results in increased expression of TNF protein]; caryophyllene inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of TNF protein]; Curcumin inhibits the reaction [Fructose results in increased expression of TNF protein]; dapagliflozin inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of TNF protein]; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of TNF protein]; dapagliflozin promotes the reaction [Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of TNF protein]]; Fenofibrate inhibits the reaction [Fructose results in increased expression of and results in increased secretion of TNF protein]; Fructose inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF protein]; Fructose promotes the reaction [bisphenol A results in increased expression of TNF protein]; Fructose results in increased expression of and results in increased secretion of TNF protein; galangin inhibits the reaction [Fructose results in increased expression of TNF mRNA]; galangin inhibits the reaction [Fructose results in increased expression of TNF protein]; Genistein inhibits the reaction [Fructose results in increased expression of TNF protein]; geraniol inhibits the reaction [Fructose results in increased secretion of TNF protein]; iodopravadoline inhibits the reaction [caryophyllene inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of TNF protein]]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of TNF protein]; Metformin inhibits the reaction [Fructose results in increased expression of TNF protein]; Ozone promotes the reaction [Fructose results in increased expression of TNF mRNA]; Particulate Matter promotes the reaction [Fructose results in increased expression of TNF mRNA]; Pioglitazone inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of TNF protein]; Pioglitazone inhibits the reaction [Fructose results in increased secretion of TNF protein]; Quercetin inhibits the reaction [Fructose results in increased expression of TNF protein]; Resveratrol inhibits the reaction [Fructose results in increased expression of and results in increased secretion of TNF protein]; Resveratrol inhibits the reaction [Fructose results in increased expression of TNF protein]; Rutin inhibits the reaction [Fructose results in increased expression of TNF protein]; tributylhexadecylphosphonium bromide inhibits the reaction [Fructose results in increased expression of TNF protein] | PMID:10090849 PMID:21704028 PMID:21708140 PMID:22426011 PMID:23968387 PMID:24508943 PMID:25108154 PMID:25679220 PMID:25813056 PMID:26358169 PMID:26713546 PMID:26973390 PMID:30343038 PMID:30551545 PMID:31661889 PMID:34656705 PMID:34939712 | Tnf | increases expression | ISO | Tnf (Mus musculus) | 6480464 | CTD | Fructose results in increased expression of TNF mRNA; Fructose results in increased expression of TNF protein | PMID:27531227 PMID:28257781 PMID:31672515 | Tnf | increases secretion | ISO | Tnf (Mus musculus) | 6480464 | CTD | Fructose results in increased secretion of TNF protein | PMID:28257781 | Tnf | multiple interactions | ISO | Tnf (Mus musculus) | 6480464 | CTD | [Dietary Fats co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Ethanol] results in increased expression of TNF protein; [Dietary Fats co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose] results in increased expression of TNF protein; Fructose promotes the reaction [Ethanol results in increased expression of TNF mRNA] | PMID:26858005 PMID:37271273 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |