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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3876
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tnf
Name: tumor necrosis factor
Acc ID: CHEBI:48707
Term: (-)-citrinin
Definition: A citrinin that has formula C13H14O5.
Chemical ID: MESH:D002953
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tnfmultiple interactionsISOTnf (Mus musculus)6480464CTDCitrinin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Citrinin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Citrinin inhibits the reaction [Poly I-C results in increased expression of TNF mRNA]; Citrinin inhibits the reaction [Poly I-C results in increased expression of TNF protein]; Citrinin promotes the reaction [CPG-oligonucleotide results in increased expression of TNF mRNA]; Citrinin promotes the reaction [CPG-oligonucleotide results in increased expression of TNF protein]PMID:22771370
Tnfmultiple interactionsISOTNF (Homo sapiens)6480464CTD[ochratoxin A co-treated with Citrinin] results in increased expression of TNF mRNA; [ochratoxin A co-treated with Citrinin] results in increased expression of TNF protein; pyrazolanthrone inhibits the reaction [[ochratoxin A co-treated with Citrinin] results in increased expression of TNF mRNA]; U 0126 inhibits the reaction [[ochratoxin A co-treated with Citrinin] results in increased expression of TNF mRNA]PMID:29673704
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