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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3876
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tnf
Name: tumor necrosis factor
Acc ID: CHEBI:37208
Term: pinitol
Definition: A cyclitol ether formed by etherification of the 3-hydroxy group of chiro-inositol. It is plant metabolite isolated from the leaves of Sutherlandia frutescens.
Chemical ID: MESH:C021730
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tnfmultiple interactionsEXP 6480464CTDpinitol inhibits the reaction [Streptozocin results in increased expression of TNF protein]PMID:20643114
Tnfmultiple interactionsISORGD:114296480464CTDpinitol inhibits the reaction [Cisplatin results in increased expression of TNF protein]PMID:29752894
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