Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3876
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tnf
Name: tumor necrosis factor
Acc ID: CHEBI:30187
Term: aluminium oxide
Definition: null
Chemical ID: MESH:D000537
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tnfincreases activityEXP 6480464CTDAluminum Oxide results in increased activity of TNF proteinPMID:11306444
Tnfincreases expressionEXP 6480464CTDAluminum Oxide results in increased expression of TNF mRNAPMID:35403826
Tnfmultiple interactionsEXP 6480464CTDsesamol inhibits the reaction [Aluminum Oxide results in increased expression of TNF mRNA]PMID:35403826
Tnfaffects secretionISOTNF (Homo sapiens)6480464CTDAluminum Oxide affects the secretion of TNF proteinPMID:10413987
Tnfincreases expressionISOTNF (Homo sapiens)6480464CTDAluminum Oxide results in increased expression of TNF mRNAPMID:15183442 PMID:16488289
Tnfmultiple interactionsISOTnf (Mus musculus)6480464CTD[Aluminum Oxide co-treated with Nanotubes, Carbon] results in increased expression of TNF mRNAPMID:25216247
Tnfmultiple interactionsISOTNF (Homo sapiens)6480464CTDAluminum Oxide inhibits the reaction [Nanotubes, Carbon results in increased secretion of TNF protein]PMID:25216247
Go Back to source page   Continue to Ontology report