Cyp2c24 (cytochrome P450, family 2, subfamily c, polypeptide 24) - Rat Genome Database

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Gene: Cyp2c24 (cytochrome P450, family 2, subfamily c, polypeptide 24) Rattus norvegicus
Analyze
Symbol: Cyp2c24
Name: cytochrome P450, family 2, subfamily c, polypeptide 24
RGD ID: 1563697
Description: Predicted to enable heme binding activity and monooxygenase activity. Predicted to be involved in epoxygenase P450 pathway; retinoic acid metabolic process; and xenobiotic metabolic process. Predicted to act upstream of or within arachidonic acid metabolic process and linoleic acid metabolic process. Predicted to be located in plasma membrane. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in several diseases, including Plasmodium falciparum malaria; carcinoma (multiple); eosinophilic esophagitis; glucose metabolism disease (multiple); and invasive aspergillosis. Orthologous to several human genes including CYP2C18 (cytochrome P450 family 2 subfamily C member 18); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC499353; RGD1563697; similar to Cytochrome P450 2C24 (CYPIIC24) (P450-PROS2)
RGD Orthologs
Mouse
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81246,286,341 - 246,348,607 (+)NCBIGRCr8
mRatBN7.21236,873,967 - 236,936,238 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1236,873,967 - 236,936,238 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1245,297,865 - 245,365,048 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01252,191,120 - 252,253,394 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01245,029,377 - 245,091,647 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01258,074,797 - 258,139,176 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1258,074,860 - 258,139,176 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01265,526,375 - 265,590,930 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41243,374,165 - 243,579,050 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1233,976,115 - 234,021,371 (+)NCBICelera
Cytogenetic Map1q53NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1,4-dichlorobenzene  (ISO)
1-naphthyl isothiocyanate  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
4-hydroxytolbutamide  (ISO)
acetamide  (EXP)
aflatoxin B1  (EXP,ISO)
ammonium chloride  (EXP)
Aroclor 1254  (ISO)
benzo[a]pyrene  (ISO)
beta-hexachlorocyclohexane  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP)
captan  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
cyanocob(III)alamin  (ISO)
cyclosporin A  (ISO)
cyproconazole  (EXP,ISO)
cyproterone acetate  (ISO)
dextran sulfate  (ISO)
dichloroacetic acid  (ISO)
diclofenac  (ISO)
difenoconazole  (ISO)
dimethyl sulfoxide  (ISO)
dioxygen  (ISO)
endosulfan  (EXP)
epoxiconazole  (ISO)
ethanol  (ISO)
etoposide  (ISO)
finasteride  (EXP)
fluconazole  (ISO)
flutamide  (EXP)
folic acid  (ISO)
furan  (EXP)
glycine betaine  (ISO)
Heptachlor epoxide  (ISO)
indole-3-methanol  (EXP)
inulin  (ISO)
L-methionine  (ISO)
lipopolysaccharide  (ISO)
methidathion  (ISO)
monosodium L-glutamate  (ISO)
N-nitrosodiethylamine  (EXP)
orphenadrine  (EXP)
paracetamol  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenformin  (EXP)
phenobarbital  (ISO)
pioglitazone  (ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
prochloraz  (EXP,ISO)
propiconazole  (ISO)
rotenone  (EXP)
sodium arsenite  (ISO)
succimer  (ISO)
sulfasalazine  (ISO)
tetrachloromethane  (EXP,ISO)
thiacloprid  (ISO)
thioacetamide  (EXP)
thiophanate-methyl  (ISO)
titanium dioxide  (ISO)
tolbutamide  (ISO)
triadimefon  (ISO)
trichloroethene  (EXP)
triptonide  (ISO)
valproic acid  (ISO)
verteporfin  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)
ziram  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7916606   PMID:11093772   PMID:15102943   PMID:29351317  


Genomics

Comparative Map Data
Cyp2c24
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81246,286,341 - 246,348,607 (+)NCBIGRCr8
mRatBN7.21236,873,967 - 236,936,238 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1236,873,967 - 236,936,238 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1245,297,865 - 245,365,048 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01252,191,120 - 252,253,394 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01245,029,377 - 245,091,647 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01258,074,797 - 258,139,176 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1258,074,860 - 258,139,176 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01265,526,375 - 265,590,930 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41243,374,165 - 243,579,050 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1233,976,115 - 234,021,371 (+)NCBICelera
Cytogenetic Map1q53NCBI
Cyp2c55
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391938,995,384 - 39,031,134 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1938,995,463 - 39,031,137 (+)EnsemblGRCm39 Ensembl
GRCm381939,006,940 - 39,042,690 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1939,007,019 - 39,042,693 (+)EnsemblGRCm38mm10GRCm38
MGSCv371939,081,509 - 39,117,177 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361939,072,063 - 39,107,731 (+)NCBIMGSCv36mm8
Celera1939,809,823 - 39,845,531 (+)NCBICelera
Cytogenetic Map19C3NCBI
cM Map1933.64NCBI

Variants

.
Variants in Cyp2c24
206 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:152
Count of miRNA genes:105
Interacting mature miRNAs:112
Transcripts:ENSRNOT00000001990, ENSRNOT00000054729
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7794788Mcs32Mammary carcinoma susceptibility QTL 322.61mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)1115540693238914717Rat
7421630Bp362Blood pressure QTL 3620.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1118608292241799120Rat
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1144267353251128347Rat
724531Uae5Urinary albumin excretion QTL 54urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)1150700142252085212Rat
1578759Uae30Urinary albumin excretion QTL 303.30.003urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1150700247252085048Rat
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1150700247252085048Rat
1354610Bw34Body weight QTL 344.1body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512256448636Rat
1354661Bw33Body weight QTL 335.2body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
1549837Hcar15Hepatocarcinoma resistance QTL 150.05liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1153136852260522016Rat
1354580Scort1Serum corticosterone level QTL 13.4blood corticosterone amount (VT:0005345)blood corticosterone level (CMO:0001172)1156677124256448636Rat
2292220Bp306Blood pressure QTL 3063.470.00087arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1164310393243914901Rat
738032Hcas5Hepatocarcinoma susceptibility QTL 53.12liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1176426412257976495Rat
1354624Cm35Cardiac mass QTL355.7heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1177227632256448636Rat
1354652Kidm20Kidney mass QTL 204.3kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1177227632256448636Rat
634321Hc1Hypercalciuria QTL 12.91urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1178810256240830002Rat
1578763Kidm29Kidney mass QTL 293.30.0001kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1179567751260522016Rat
8655655Arrd2Age-related retinal degeneration QTL 27.79retinal layer morphology trait (VT:0003727)percentage of study population developing retinopathy during a period of time (CMO:0002453)1183970203243914901Rat
8655855Arrd3Age-related retinal degeneration QTL 33.07lens clarity trait (VT:0001304)cataract incidence/prevalence measurement (CMO:0001585)1183970203243914901Rat
1358898Bp255Blood pressure QTL 2553.6arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1191019702246062233Rat
1358191Ept10Estrogen-induced pituitary tumorigenesis QTL 103.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)1192825253243914732Rat
8552891Epfw5Epididymal fat weight QTL 54.4epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1193113876238113876Rat
1600388Niddm67Non-insulin dependent diabetes mellitus QTL 675.840.000004blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1195804352257091168Rat
1600395Niddm69Non-insulin dependent diabetes mellitus QTL 694.140.0002blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1195804352257091168Rat
1600396Niddm68Non-insulin dependent diabetes mellitus QTL 684.970.0003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1195804352257091168Rat
631658Cm7Cardiac mass QTL 75.320.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)1196248093241248093Rat
1358292Cm37Cardiac mass QTL 376.20.00000081heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)1196248093241248093Rat
1600374Mcs17Mammary carcinoma susceptibility QTL 173mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1197670404242670404Rat
1641926Teswt2Testicular weight QTL 22.82testis mass (VT:1000644)both testes wet weight (CMO:0000175)1197697768238755659Rat
2302375Bw83Body weight QTL 834.870.0002body mass (VT:0001259)body weight (CMO:0000012)1197697768242697768Rat
61376Bp42Blood pressure QTL 4223.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1197814409242814409Rat
1298084Thym4Thymus enlargement QTL 410.68thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)1197814409242814409Rat
1357335Bw39Body weight QTL 393.3body mass (VT:0001259)body weight (CMO:0000012)1197814409242814409Rat
634313Niddm43Non-insulin dependent diabetes mellitus QTL 43blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1199050459259647894Rat
2293694Bss38Bone structure and strength QTL 387.050.0001femur strength trait (VT:0010010)femur stiffness (CMO:0001674)1201554356246554356Rat
7394701Uae46Urinary albumin excretion QTL 463.60.0056urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1201554356246554356Rat
2300175Bmd40Bone mineral density QTL 4015.40.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)1201554356246554356Rat
2293655Bss36Bone structure and strength QTL 3610.660.0001femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)1201554356246554356Rat
2293674Bss39Bone structure and strength QTL 397.10.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)1201554356246554356Rat
10059587Bw173Body weight QTL 1733.230.025body mass (VT:0001259)body weight (CMO:0000012)1202069611247069611Rat
1600363Hc6Hypercalciuria QTL 62.7urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1203995416244113296Rat
1600397Edcs4Endometrial carcinoma susceptibility QTL 42.2uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)1206081677251081677Rat
1357399Bw45Body weight QTL 453.05body mass (VT:0001259)body mass index (BMI) (CMO:0000105)1206329708251329708Rat
1357404Bw42Body weight QTL 424.490.0001body mass (VT:0001259)body weight (CMO:0000012)1206329708251329708Rat
1358916Kidm22Kidney mass QTL 223.32kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1210702053240947965Rat
1358890Bp259Blood pressure QTL 2593.06arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1210702053260522016Rat
2292216Bw80Body weight QTL 803.230.0019body mass (VT:0001259)body weight (CMO:0000012)1213533809243914901Rat
724538Kidm1Kidney mass QTL 13.2kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1213707201252085212Rat
734768Niddm59Non-insulin dependent diabetes mellitus QTL 59body mass (VT:0001259)body weight (CMO:0000012)1213843987258843987Rat
61455Niddm7Non-insulin dependent diabetes mellitus QTL 75.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1214537555238757011Rat
70211Niddm24Non-insulin dependent diabetes mellitus QTL 243.79blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1214647894259647894Rat
1549910Bw54Body weight QTL 540.05body mass (VT:0001259)body weight (CMO:0000012)1214647894259647894Rat
61327Eae7Experimental allergic encephalomyelitis QTL 75.6body mass (VT:0001259)change in body weight (CMO:0002045)1216255568260522016Rat
2302040Pia35Pristane induced arthritis QTL 353.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)1216255568260522016Rat
1598821Rf55Renal function QTL 556.3renal blood flow trait (VT:2000006)ratio of change in renal blood flow to change in renal perfusion pressure (CMO:0001239)1218748008257976495Rat
61400Niddm1Non-insulin dependent diabetes mellitus QTL 111blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1218753689245907899Rat
724533Rf51Renal function QTL 515.30.0002kidney plasma flow trait (VT:0005524)renal plasma flow (CMO:0001914)1218753816256448513Rat
731175Uae20Urinary albumin excretion QTL 203.50.0018urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1221264111259647894Rat
10053715Scort24Serum corticosterone level QTL 242.130.0088blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1221414816260522016Rat
724552Glom2Glomerulus QTL 23.30.0001kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)1222363780260522016Rat
1600392Bw123Body weight QTL 1230.001body mass (VT:0001259)body weight (CMO:0000012)1223201027260522016Rat
2293700Bmd27Bone mineral density QTL 276.60.0001femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)1224054293243747962Rat
2293701Bmd34Bone mineral density QTL 348.30.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)1224054293243747962Rat
734767Niddm57Non-insulin dependent diabetes mellitus QTL 57body mass (VT:0001259)body weight (CMO:0000012)1224054293260122809Rat
631843Bw116Body weight QTL 1164.10.016abdominal adipose amount (VT:1000220)abdominal fat pad weight (CMO:0000088)1224054293260122809Rat
734769Niddm58Non-insulin dependent diabetes mellitus QTL 58body mass (VT:0001259)body weight (CMO:0000012)1224569538260122809Rat
631215Stl8Serum triglyceride level QTL 89.270.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1225126575260522016Rat
1300108Rf8Renal function QTL 83.75renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)1228581588259647894Rat
2316896Gluco57Glucose level QTL 577.2blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1228985440245907899Rat
1581544Rf52Renal function QTL 520.05urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)1232156370259647894Rat
631669Iddm9Insulin dependent diabetes mellitus QTL 92.80.039blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1233190394258625266Rat
631536Lnnr2Liver neoplastic nodule remodeling QTL 22.90.0005liver integrity trait (VT:0010547)liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)1233948574260522016Rat
631690Scl5Serum cholesterol level QTL 52.1blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1236125214260522016Rat

Markers in Region
RH143759  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21236,927,295 - 236,927,486 (+)MAPPERmRatBN7.2
mRatBN7.2179,313,674 - 9,313,865 (+)MAPPERmRatBN7.2
Rnor_6.0179,842,571 - 9,842,761NCBIRnor6.0
Rnor_6.01258,130,238 - 258,130,428NCBIRnor6.0
Rnor_5.01711,952,251 - 11,952,441UniSTSRnor5.0
Rnor_5.01265,581,992 - 265,582,182UniSTSRnor5.0
RGSC_v3.41715,358,410 - 15,358,600UniSTSRGSC3.4
RGSC_v3.41715,360,920 - 15,361,110UniSTSRGSC3.4
Celera179,392,045 - 9,392,235UniSTS
Celera1234,012,432 - 234,012,622UniSTS
RH 3.4 Map1783.1UniSTS
Cytogenetic Map1q53UniSTS
BE116223  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21236,928,239 - 236,928,459 (+)MAPPERmRatBN7.2
mRatBN7.2179,314,618 - 9,314,838 (+)MAPPERmRatBN7.2
Rnor_6.0179,843,515 - 9,843,734NCBIRnor6.0
Rnor_6.01258,131,182 - 258,131,401NCBIRnor6.0
Rnor_5.01711,953,195 - 11,953,414UniSTSRnor5.0
Rnor_5.01265,582,936 - 265,583,155UniSTSRnor5.0
RGSC_v3.41715,361,864 - 15,362,083UniSTSRGSC3.4
Celera179,392,989 - 9,393,208UniSTS
Celera1234,013,376 - 234,013,595UniSTS
RH 3.4 Map1781.4UniSTS
Cytogenetic Map1q53UniSTS
RH141754  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21236,925,717 - 236,925,932 (+)MAPPERmRatBN7.2
mRatBN7.2179,312,098 - 9,312,313 (+)MAPPERmRatBN7.2
Rnor_6.0179,840,995 - 9,841,209NCBIRnor6.0
Rnor_6.01258,128,365 - 258,128,579NCBIRnor6.0
Rnor_5.01711,950,675 - 11,950,889UniSTSRnor5.0
Rnor_5.01265,580,119 - 265,580,333UniSTSRnor5.0
RGSC_v3.41715,356,834 - 15,357,048UniSTSRGSC3.4
RGSC_v3.41715,359,342 - 15,359,556UniSTSRGSC3.4
Celera179,390,469 - 9,390,683UniSTS
Celera1234,010,856 - 234,011,070UniSTS
RH 3.4 Map1752.6UniSTS
Cytogenetic Map1q53UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system endocrine system exocrine system hemolymphoid system hepatobiliary system nervous system renal system reproductive system respiratory system
High
Medium 2 4 4 4 5
Low 1 3 3 3 4 2
Below cutoff 4 3 1 3 1 4 6 1

Sequence


RefSeq Acc Id: ENSRNOT00000054729   ⟹   ENSRNOP00000051612
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1236,873,967 - 236,936,238 (+)Ensembl
Rnor_6.0 Ensembl1258,074,860 - 258,139,176 (+)Ensembl
RefSeq Acc Id: NM_001271354   ⟹   NP_001258283
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81246,286,341 - 246,348,607 (+)NCBI
mRatBN7.21236,873,967 - 236,936,238 (+)NCBI
Rnor_6.01258,074,860 - 258,139,176 (+)NCBI
Rnor_5.01265,526,375 - 265,590,930 (+)NCBI
Celera1233,976,115 - 234,021,371 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001258283 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB26468 (Get FASTA)   NCBI Sequence Viewer  
  AAB26469 (Get FASTA)   NCBI Sequence Viewer  
  AAB26471 (Get FASTA)   NCBI Sequence Viewer  
  AAB26472 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000051612
  ENSRNOP00000051612.4
RefSeq Acc Id: NP_001258283   ⟸   NM_001271354
- Peptide Label: precursor
- UniProtKB: P33273 (UniProtKB/Swiss-Prot),   F1M0F9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000051612   ⟸   ENSRNOT00000054729

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1M0F9-F1-model_v2 AlphaFold F1M0F9 1-490 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13690889
Promoter ID:EPDNEW_R1414
Type:single initiation site
Name:Cyp2c24_1
Description:cytochrome P450, family 2, subfamily c, polypeptide 24
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01258,074,861 - 258,074,921EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1563697 AgrOrtholog
BioCyc Gene G2FUF-55768 BioCyc
Ensembl Genes ENSRNOG00000013241 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000054729 ENTREZGENE
  ENSRNOT00000054729.5 UniProtKB/TrEMBL
Gene3D-CATH 1.10.630.10 UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
InterPro Cyt_P450 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyt_P450_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyt_P450_E_grp-I UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyt_P450_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:499353 UniProtKB/TrEMBL
NCBI Gene 499353 ENTREZGENE
PANTHER CYTOCHROME P450 2C55 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CYTOCHROME P450 508A4-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam p450 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cyp2c24 PhenoGen
PRINTS EP450I UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P450 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE CYTOCHROME_P450 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000013241 RatGTEx
Superfamily-SCOP Cytochrome P450 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt CP255_RAT UniProtKB/Swiss-Prot
  F1M0F9 ENTREZGENE, UniProtKB/TrEMBL
  P33273 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-05-24 Cyp2c24  cytochrome P450, family 2, subfamily c, polypeptide 24  LOC687842  similar to Cytochrome P450 2C24 (CYPIIC24) (P450-PROS2)  Data merged from RGD:1596261 1643240 APPROVED
2008-04-30 Cyp2c24  cytochrome P450, family 2, subfamily c, polypeptide 24   Cyp2c24_predicted  cytochrome P450, family 2, subfamily c, polypeptide 24 (predicted)  'predicted' is removed 2292626 APPROVED
2007-07-06 Cyp2c24_predicted  cytochrome P450, family 2, subfamily c, polypeptide 24 (predicted)  RGD1563697_predicted  similar to Cytochrome P450 2C24 (CYPIIC24) (P450-PROS2) (predicted)  Name updated 1299863 APPROVED
2006-11-20 LOC687842  similar to Cytochrome P450 2C24 (CYPIIC24) (P450-PROS2)      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-03-07 RGD1563697_predicted  similar to Cytochrome P450 2C24 (CYPIIC24) (P450-PROS2) (predicted)  LOC499353  similar to Cytochrome P450 2C24 (CYPIIC24) (P450-PROS2)  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC499353  similar to Cytochrome P450 2C24 (CYPIIC24) (P450-PROS2)      Symbol and Name status set to provisional 70820 PROVISIONAL