Gene: Ikbkb (inhibitor of nuclear factor kappa B kinase subunit beta) Rattus norvegicus
Symbol: Ikbkb
Name: inhibitor of nuclear factor kappa B kinase subunit beta
Description: ENCODES a protein that exhibits ATP binding; protein heterodimerization activity; identical protein binding (ortholog); INVOLVED IN neuron projection development; positive regulation of cell proliferation; positive regulation of neuron death; PARTICIPATES IN adenosine signaling pathway; FasL mediated signaling pathway; granulocyte-macrophage colony-stimulating factor signaling pathway; ASSOCIATED WITH Alzheimer's Disease; Arthritis, Experimental; Colitis; FOUND IN cytosol; IkappaB kinase complex; intracellular membrane-bounded organelle; INTERACTS WITH (-)-epigallocatechin 3-gallate; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AIM-1; I-kappa-B kinase 2; I-kappa-B-kinase beta; IKK-B; IKK-beta; IKK2; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta; inhibitor of kappaB kinase beta; inhibitor of nuclear factor kappa B kinase beta subunit; inhibitor of nuclear factor kappa-B kinase subunit beta; NFKBIKB; nuclear factor NF-kappa-B inhibitor kinase beta
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01674,177,233 - 74,230,809 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01673,809,854 - 73,863,636 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41673,804,730 - 73,858,510 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11673,805,346 - 73,858,348 (+)NCBI
Celera1667,214,025 - 67,266,348 (+)NCBICelera
Cytogenetic Map16q12.5NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Ikbkb
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621375
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2018-04-10
Status: ACTIVE