(+)-artemisinin multiple interactions ISO IKBKB (Homo sapiens) 6480464 artemisinin inhibits the reaction [Simvastatin results in increased phosphorylation of IKBKB protein] CTD PMID:18463201 (+)-catechin multiple interactions EXP 6480464 Catechin inhibits the reaction [Rotenone results in increased expression of IKBKB mRNA] CTD PMID:35337893 (-)-epigallocatechin 3-gallate multiple interactions ISO IKBKB (Homo sapiens) 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of IKBKB mRNA CTD PMID:22079256 (-)-epigallocatechin 3-gallate decreases expression EXP 6480464 epigallocatechin gallate results in decreased expression of IKBKB protein modified form CTD PMID:27659729 (1->4)-beta-D-glucan multiple interactions ISO Ikbkb (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of IKBKB mRNA CTD PMID:36331819 (R,R,R)-alpha-tocopherol multiple interactions ISO IKBKB (Homo sapiens) 6480464 alpha-Tocopherol inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of IKBKB protein] CTD PMID:34310962 (S)-colchicine increases phosphorylation ISO IKBKB (Homo sapiens) 6480464 Colchicine results in increased phosphorylation of IKBKB protein CTD PMID:17029595 (S)-colchicine affects response to substance ISO Ikbkb (Mus musculus) 6480464 IKBKB protein affects the susceptibility to Colchicine CTD PMID:20159942 (S)-colchicine multiple interactions ISO IKBKB (Homo sapiens) 6480464 Colchicine results in decreased localization of [IKBKB protein binds to NFKBIA protein] CTD PMID:17029595 (S)-naringenin increases expression ISO Ikbkb (Mus musculus) 6480464 naringenin results in increased expression of IKBKB mRNA CTD PMID:28395574 1'-acetoxychavicol acetate multiple interactions ISO IKBKB (Homo sapiens) 6480464 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased activity of IKBKB protein] and 1'-acetoxychavicol acetate inhibits the reaction [TNF protein results in increased expression of IKBKB protein] CTD PMID:15905586 1,2-dimethylhydrazine increases expression ISO Ikbkb (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in increased expression of IKBKB mRNA CTD PMID:22206623 1,2-dimethylhydrazine multiple interactions ISO Ikbkb (Mus musculus) 6480464 Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of IKBKB mRNA] CTD PMID:22206623 1,2-naphthoquinone multiple interactions ISO Ikbkb (Mus musculus) 6480464 1 more ... CTD PMID:21139339 1,4-dithiothreitol multiple interactions ISO IKBKB (Homo sapiens) 6480464 Dithiothreitol inhibits the reaction [3 more ... CTD PMID:20584749 1,4-dithiothreitol multiple interactions ISO Ikbkb (Mus musculus) 6480464 Dithiothreitol inhibits the reaction [Melitten binds to and results in decreased activity of IKBKB protein] and Dithiothreitol inhibits the reaction [Melitten inhibits the reaction [Nitroprusside results in increased activity of IKBKB protein]] CTD PMID:17067557 15-oxo-ETE multiple interactions ISO IKBKB (Homo sapiens) 6480464 [15-keto-5 more ... CTD PMID:25450232 15-oxo-ETE decreases activity ISO IKBKB (Homo sapiens) 6480464 15-keto-5 more ... CTD PMID:25450232 17beta-estradiol multiple interactions ISO IKBKB (Homo sapiens) 6480464 Estradiol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of IKBKB protein] CTD PMID:26220752 2,2',5,5'-tetrachlorobiphenyl increases expression ISO IKBKB (Homo sapiens) 6480464 2 more ... CTD PMID:36804509 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Ikbkb (Mus musculus) 6480464 Colforsin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of IKBKB mRNA] and N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of IKBKB mRNA] CTD PMID:17407152 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of IKBKB mRNA CTD PMID:33387578 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Ikbkb (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of IKBKB mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Ikbkb (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of IKBKB mRNA CTD PMID:17407152 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of and results in increased phosphorylation of IKBKB protein CTD PMID:12361703 2,6-dinitrotoluene affects expression EXP 6480464 2 and 6-dinitrotoluene affects the expression of IKBKB mRNA CTD PMID:21346803 2-acetamidofluorene increases activity ISO IKBKB (Homo sapiens) 6480464 2-Acetylaminofluorene results in increased activity of IKBKB protein CTD PMID:11960367 2-amino-2-deoxy-D-galactopyranose multiple interactions EXP 6480464 mangiferin inhibits the reaction [Galactosamine results in increased phosphorylation of IKBKB protein] CTD PMID:22310181 2-amino-2-deoxy-D-galactopyranose increases phosphorylation EXP 6480464 Galactosamine results in increased phosphorylation of IKBKB protein CTD PMID:22310181 2-amino-2-deoxy-D-glucopyranose multiple interactions ISO Ikbkb (Mus musculus) 6480464 Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of IKBKB protein] CTD PMID:18786831 2-tert-butylhydroquinone multiple interactions EXP 6480464 2-tert-butylhydroquinone inhibits the reaction [Sodium Chloride and Dietary results in increased expression of IKBKB protein modified form] CTD PMID:28844481 3-chloropropane-1,2-diol increases expression EXP 6480464 alpha-Chlorohydrin results in increased expression of IKBKB protein CTD PMID:34915118 3-phenylprop-2-enal decreases phosphorylation EXP 6480464 cinnamaldehyde results in decreased phosphorylation of IKBKB protein CTD PMID:17486422 4-vinylcyclohexene dioxide affects expression ISO Ikbkb (Mus musculus) 6480464 4-vinyl-1-cyclohexene dioxide affects the expression of IKBKB mRNA CTD PMID:20829426 5-aza-2'-deoxycytidine increases expression ISO Ikbkb (Mus musculus) 6480464 Decitabine results in increased expression of IKBKB mRNA CTD PMID:27915011 5-fluorouracil decreases expression ISO IKBKB (Homo sapiens) 6480464 Fluorouracil results in decreased expression of IKBKB protein CTD PMID:30177839 [6]-Shogaol multiple interactions ISO IKBKB (Homo sapiens) 6480464 shogaol analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased expression of IKBKB protein] CTD PMID:23899529 acetylsalicylic acid decreases activity ISO IKBKB (Homo sapiens) 6480464 Aspirin results in decreased activity of IKBKB protein CTD PMID:16199534 acetylsalicylic acid decreases phosphorylation EXP 6480464 Aspirin results in decreased phosphorylation of IKBKB protein CTD PMID:16310244 acetylsalicylic acid decreases expression ISO Ikbkb (Mus musculus) 6480464 Aspirin results in decreased expression of IKBKB protein CTD PMID:16880202 acrolein affects metabolic processing ISO IKBKB (Homo sapiens) 6480464 Acrolein affects the metabolism of IKBKB protein CTD PMID:15650393 acrolein multiple interactions ISO IKBKB (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of and results in increased oxidation of IKBKB mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of and results in increased oxidation of IKBKB mRNA CTD PMID:32699268 afatinib decreases expression ISO IKBKB (Homo sapiens) 6480464 afatinib results in decreased expression of IKBKB protein CTD PMID:22242139 aflatoxin B1 increases expression ISO Ikbkb (Mus musculus) 6480464 Aflatoxin B1 results in increased expression of IKBKB mRNA CTD PMID:19770486 aflatoxin B1 multiple interactions EXP 6480464 [Aflatoxin B1 co-treated with caryophyllene] results in increased expression of IKBKB protein CTD PMID:34506763 aflatoxin B1 increases methylation ISO IKBKB (Homo sapiens) 6480464 Aflatoxin B1 results in increased methylation of IKBKB gene CTD PMID:27153756 aldehydo-D-glucosamine multiple interactions ISO Ikbkb (Mus musculus) 6480464 Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of IKBKB protein] CTD PMID:18786831 aldehydo-D-glucose multiple interactions EXP 6480464 IKBKB affects the reaction [IL1B protein inhibits the reaction [Glucose results in increased expression of INS2 mRNA alternative form]] more ... CTD PMID:22558381 aldehydo-D-glucose multiple interactions ISO Ikbkb (Mus musculus) 6480464 IKBKB protein affects the reaction [Particulate Matter promotes the reaction [Glucose results in increased secretion of INS1 protein]] CTD PMID:31095431 aldehydo-D-ribose increases phosphorylation ISO Ikbkb (Mus musculus) 6480464 Ribose results in increased phosphorylation of IKBKB protein CTD PMID:30101366 all-trans-retinoic acid decreases expression ISO IKBKB (Homo sapiens) 6480464 Tretinoin results in decreased expression of IKBKB mRNA CTD PMID:23724009 allopurinol multiple interactions EXP 6480464 Allopurinol inhibits the reaction [Fructose results in increased phosphorylation of IKBKB protein] CTD PMID:24491314 alpha-pinene multiple interactions ISO IKBKB (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of and results in increased oxidation of IKBKB mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of and results in increased oxidation of IKBKB mRNA CTD PMID:32699268 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of IKBKB mRNA CTD PMID:16483693 anethole decreases activity ISO IKBKB (Homo sapiens) 6480464 anethole results in decreased activity of IKBKB protein CTD PMID:10871845 aniline increases phosphorylation EXP 6480464 aniline results in increased phosphorylation of IKBKB protein CTD PMID:18420242 aniline increases expression EXP 6480464 aniline results in increased expression of IKBKB protein CTD PMID:18420242 anthocyanin multiple interactions ISO Ikbkb (Mus musculus) 6480464 Anthocyanins inhibits the reaction [Dietary Fats results in increased phosphorylation of IKBKB protein] CTD PMID:24795233 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions EXP 6480464 pyrazolanthrone inhibits the reaction [sodium arsenite results in increased phosphorylation of IKBKB protein] CTD PMID:19616567 apigenin multiple interactions ISO IKBKB (Homo sapiens) 6480464 Apigenin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of IKBKB protein] more ... CTD PMID:24148603 and PMID:36350155 apigenin multiple interactions ISO Ikbkb (Mus musculus) 6480464 Apigenin inhibits the reaction [Ovalbumin results in increased phosphorylation of IKBKB protein] CTD PMID:36350155 apigenin multiple interactions EXP 6480464 Apigenin inhibits the reaction [Freund's Adjuvant results in increased phosphorylation of IKBKB protein] and Apigenin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of IKBKB protein] CTD PMID:25557508 and PMID:25935278 aristolochic acid A increases expression ISO IKBKB (Homo sapiens) 6480464 aristolochic acid I results in increased expression of IKBKB mRNA CTD PMID:33212167 arjunolic acid multiple interactions ISO Ikbkb (Mus musculus) 6480464 arjunolic acid inhibits the reaction [Cadmium Chloride results in increased phosphorylation of IKBKB protein] CTD PMID:21420465 Aroclor 1254 multiple interactions EXP 6480464 [Chlorodiphenyl (54% Chlorine) co-treated with aroclor 1242 co-treated with aroclor 1248] results in increased expression of IKBKB mRNA CTD PMID:29879404 arsane decreases expression ISO IKBKB (Homo sapiens) 6480464 Arsenic results in decreased expression of IKBKB mRNA CTD PMID:19945496 and PMID:31864032 arsane affects methylation ISO IKBKB (Homo sapiens) 6480464 Arsenic affects the methylation of IKBKB gene CTD PMID:25304211 arsane affects response to substance ISO Ikbkb (Mus musculus) 6480464 IKBKB protein affects the susceptibility to Arsenic CTD PMID:20159942 arsenic atom decreases expression ISO IKBKB (Homo sapiens) 6480464 Arsenic results in decreased expression of IKBKB mRNA CTD PMID:19945496 and PMID:31864032 arsenic atom affects methylation ISO IKBKB (Homo sapiens) 6480464 Arsenic affects the methylation of IKBKB gene CTD PMID:25304211 arsenic atom affects response to substance ISO Ikbkb (Mus musculus) 6480464 IKBKB protein affects the susceptibility to Arsenic CTD PMID:20159942 arsenic trichloride multiple interactions ISO Ikbkb (Mus musculus) 6480464 IKBKB affects the reaction [arsenic trichloride results in increased expression of DDIT3 mRNA] more ... CTD PMID:16283526 arsenite(3-) multiple interactions ISO IKBKB (Homo sapiens) 6480464 arsenite inhibits the reaction [4' more ... CTD PMID:10967126 and PMID:30177839 arsenite(3-) decreases expression ISO IKBKB (Homo sapiens) 6480464 arsenite results in decreased expression of IKBKB mRNA and arsenite results in decreased expression of IKBKB protein CTD PMID:30177839 arsenite(3-) decreases activity ISO IKBKB (Homo sapiens) 6480464 arsenite results in decreased activity of IKBKB protein CTD PMID:10967126 arsenous acid increases expression ISO IKBKB (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of IKBKB mRNA CTD PMID:29633893 arsenous acid decreases expression ISO IKBKB (Homo sapiens) 6480464 Arsenic Trioxide results in decreased expression of IKBKB mRNA and Arsenic Trioxide results in decreased expression of IKBKB protein CTD PMID:19763917 and PMID:22988968 arsenous acid multiple interactions ISO IKBKB (Homo sapiens) 6480464 [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of IKBKB protein] which results in increased phosphorylation of and results in increased ubiquitination of and results in increased degradation of CCND1 protein more ... CTD PMID:22988968 and PMID:23949314 atorvastatin calcium multiple interactions ISO Ikbkb (Mus musculus) 6480464 Atorvastatin inhibits the reaction [Sodium Glutamate results in increased phosphorylation of IKBKB protein] CTD PMID:19800637 Atractylodin multiple interactions ISO IKBKB (Homo sapiens) 6480464 atractylodin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of IKBKB protein] CTD PMID:34152691 Atractylodin multiple interactions ISO Ikbkb (Mus musculus) 6480464 atractylodin inhibits the reaction [Ovalbumin results in increased phosphorylation of IKBKB protein] CTD PMID:34152691 azadirachtin A decreases expression ISO IKBKB (Homo sapiens) 6480464 azadirachtin results in decreased expression of IKBKB protein CTD PMID:20429769 benzene increases expression ISO Ikbkb (Mus musculus) 6480464 Benzene results in increased expression of IKBKB mRNA CTD PMID:33502539 benzo[a]pyrene decreases methylation ISO IKBKB (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased methylation of IKBKB promoter CTD PMID:27901495 benzo[a]pyrene increases methylation ISO Ikbkb (Mus musculus) 6480464 Benzo(a)pyrene results in increased methylation of IKBKB intron CTD PMID:27901495 benzo[e]pyrene decreases methylation ISO IKBKB (Homo sapiens) 6480464 benzo(e)pyrene results in decreased methylation of IKBKB intron CTD PMID:30157460 beta-D-glucosamine multiple interactions ISO Ikbkb (Mus musculus) 6480464 Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of IKBKB protein] CTD PMID:18786831 beta-D-glucosamine 6-sulfate multiple interactions ISO IKBKB (Homo sapiens) 6480464 glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of IKBKB protein] CTD PMID:21877189 bis(2-chloroethyl) sulfide multiple interactions ISO Ikbkb (Mus musculus) 6480464 Mustard Gas results in increased phosphorylation of and results in increased activity of IKBKB protein CTD PMID:18200059 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of IKBKB mRNA CTD PMID:17010207 and PMID:25181051 bisphenol A increases expression ISO IKBKB (Homo sapiens) 6480464 bisphenol A results in increased expression of IKBKB mRNA and bisphenol A results in increased expression of IKBKB protein modified form CTD PMID:29793316 and PMID:33670352 bisphenol A multiple interactions ISO IKBKB (Homo sapiens) 6480464 [IKBKB protein co-treated with bisphenol A] results in decreased expression of APOA1 mRNA and Curcumin inhibits the reaction [bisphenol A results in increased expression of IKBKB protein modified form] CTD PMID:29793316 and PMID:31842455 bortezomib multiple interactions ISO IKBKB (Homo sapiens) 6480464 Bortezomib promotes the reaction [abexinostat results in decreased expression of IKBKB mRNA] and IKBKB protein affects the reaction [Bortezomib results in increased phosphorylation of and results in increased degradation of NFKBIA protein] CTD PMID:19417023 and PMID:24085292 bortezomib decreases expression ISO IKBKB (Homo sapiens) 6480464 Bortezomib results in decreased expression of IKBKB mRNA CTD PMID:20471514 butylated hydroxyanisole multiple interactions ISO Ikbkb (Mus musculus) 6480464 Butylated Hydroxyanisole inhibits the reaction [IKBKB protein inhibits the reaction [Diethylnitrosamine results in increased activity of MAPK8 protein]] more ... CTD PMID:18691550 butyric acid multiple interactions ISO Ikbkb (Mus musculus) 6480464 [Sodium Acetate co-treated with Butyric Acid co-treated with sodium propionate] inhibits the reaction [Fluorides results in increased expression of IKBKB mRNA] and [Sodium Acetate co-treated with Butyric Acid co-treated with sodium propionate] inhibits the reaction [Fluorides results in increased expression of IKBKB protein] CTD PMID:37269894 cadmium atom multiple interactions ISO IKBKB (Homo sapiens) 6480464 [Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in increased expression of IKBKB mRNA CTD PMID:21481475 cadmium dichloride multiple interactions ISO Ikbkb (Mus musculus) 6480464 arjunolic acid inhibits the reaction [Cadmium Chloride results in increased phosphorylation of IKBKB protein] CTD PMID:21420465 cadmium dichloride increases phosphorylation ISO Ikbkb (Mus musculus) 6480464 Cadmium Chloride results in increased phosphorylation of IKBKB protein CTD PMID:21420465 caffeine increases expression EXP 6480464 Caffeine results in increased expression of IKBKB mRNA CTD PMID:20864626 calcitriol decreases phosphorylation EXP 6480464 Calcitriol results in decreased phosphorylation of IKBKB protein CTD PMID:32147540 cannabidiol multiple interactions ISO IKBKB (Homo sapiens) 6480464 [Cannabidiol co-treated with moringin] results in decreased expression of IKBKB mRNA CTD PMID:30096889 carbon atom multiple interactions ISO IKBKB (Homo sapiens) 6480464 [Air Pollutants results in increased abundance of [Carbon co-treated with Particulate Matter]] which results in increased expression of IKBKB mRNA more ... CTD PMID:31268311 carbon nanotube increases expression ISO Ikbkb (Mus musculus) 6480464 Nanotubes and Carbon results in increased expression of IKBKB mRNA CTD PMID:30081225 Carnosol multiple interactions ISO IKBKB (Homo sapiens) 6480464 carnosol inhibits the reaction [TNF protein results in increased phosphorylation of IKBKB protein] CTD PMID:20116392 carvedilol multiple interactions EXP 6480464 carvedilol inhibits the reaction [Doxorubicin results in increased expression of IKBKB protein] CTD PMID:26036690 cefoxitin multiple interactions ISO Ikbkb (Mus musculus) 6480464 [Gentamicins co-treated with Vancomycin co-treated with Cefoxitin co-treated with Metronidazole] inhibits the reaction [Fluorides results in increased expression of IKBKB mRNA] CTD PMID:37269894 cerium trichloride increases expression ISO Ikbkb (Mus musculus) 6480464 cerous chloride results in increased expression of IKBKB mRNA and cerous chloride results in increased expression of IKBKB protein CTD PMID:21656643 chloroquine decreases expression ISO IKBKB (Homo sapiens) 6480464 Chloroquine results in decreased expression of IKBKB protein CTD PMID:26116531 chromium atom affects response to substance ISO Ikbkb (Mus musculus) 6480464 IKBKB protein affects the susceptibility to Chromium CTD PMID:11726646 chromium(6+) multiple interactions ISO Ikbkb (Mus musculus) 6480464 IKBKB protein affects the reaction [chromium hexavalent ion results in increased expression of PTGS2 mRNA] more ... CTD PMID:22472290 chrysin multiple interactions ISO IKBKB (Homo sapiens) 6480464 chrysin inhibits the reaction [nickel chloride results in increased phosphorylation of IKBKB protein] CTD PMID:30016632 cisplatin affects response to substance ISO IKBKB (Homo sapiens) 6480464 IKBKB protein affects the susceptibility to Cisplatin CTD PMID:21720550 cisplatin multiple interactions ISO Ikbkb (Mus musculus) 6480464 anemoside B4 inhibits the reaction [Cisplatin results in increased phosphorylation of IKBKB protein] CTD PMID:32991863 cisplatin increases phosphorylation ISO Ikbkb (Mus musculus) 6480464 Cisplatin results in increased phosphorylation of IKBKB protein CTD PMID:32991863 cisplatin multiple interactions EXP 6480464 2-((aminocarbonyl)amino)-5-(4-fluorophenyl)-3-thiophenecarboxamide inhibits the reaction [Cisplatin results in increased phosphorylation of IKBKB protein] and 7-hydroxycoumarin inhibits the reaction [Cisplatin results in increased expression of IKBKB protein] CTD PMID:28119452 and PMID:33522649 cisplatin increases phosphorylation EXP 6480464 Cisplatin results in increased phosphorylation of IKBKB protein CTD PMID:28119452 cisplatin increases expression ISO IKBKB (Homo sapiens) 6480464 Cisplatin results in increased expression of IKBKB mRNA CTD PMID:27392435 cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of IKBKB protein CTD PMID:33522649 cisplatin affects response to substance ISO Ikbkb (Mus musculus) 6480464 IKBKB protein affects the susceptibility to Cisplatin CTD PMID:20159942 cocaine affects expression EXP 6480464 Cocaine affects the expression of IKBKB mRNA CTD PMID:20187946 colforsin daropate hydrochloride multiple interactions ISO Ikbkb (Mus musculus) 6480464 Colforsin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of IKBKB mRNA] CTD PMID:17407152 copper atom multiple interactions ISO IKBKB (Homo sapiens) 6480464 [Chelating Agents binds to Copper] which results in increased expression of IKBKB mRNA more ... CTD PMID:19747488 and PMID:30911355 copper(0) multiple interactions ISO IKBKB (Homo sapiens) 6480464 [Chelating Agents binds to Copper] which results in increased expression of IKBKB mRNA more ... CTD PMID:19747488 and PMID:30911355 curcumin multiple interactions ISO IKBKB (Homo sapiens) 6480464 Curcumin inhibits the reaction [bisphenol A results in increased expression of IKBKB protein modified form] more ... CTD PMID:16219905 more ... curcumin multiple interactions ISO Ikbkb (Mus musculus) 6480464 Curcumin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of IKBKB protein] CTD PMID:20054000 curcumin decreases activity ISO Ikbkb (Mus musculus) 6480464 Curcumin results in decreased activity of IKBKB protein CTD PMID:16678799 curcumin decreases activity ISO IKBKB (Homo sapiens) 6480464 Curcumin results in decreased activity of IKBKB protein CTD PMID:16023083 and PMID:16219905 cytochalasin D increases phosphorylation ISO IKBKB (Homo sapiens) 6480464 Cytochalasin D results in increased phosphorylation of IKBKB protein CTD PMID:17029595 cytochalasin D multiple interactions ISO IKBKB (Homo sapiens) 6480464 Cytochalasin D results in decreased localization of [IKBKB protein binds to NFKBIA protein] CTD PMID:17029595 D-glucose multiple interactions EXP 6480464 IKBKB affects the reaction [IL1B protein inhibits the reaction [Glucose results in increased expression of INS2 mRNA alternative form]] more ... CTD PMID:22558381 D-glucose multiple interactions ISO Ikbkb (Mus musculus) 6480464 IKBKB protein affects the reaction [Particulate Matter promotes the reaction [Glucose results in increased secretion of INS1 protein]] CTD PMID:31095431 D-ribofuranose increases phosphorylation ISO Ikbkb (Mus musculus) 6480464 Ribose results in increased phosphorylation of IKBKB protein CTD PMID:30101366 deferiprone multiple interactions EXP 6480464 deferiprone inhibits the reaction [ferrous sulfate results in increased activity of [CHUK protein binds to IKBKB protein]] and deferiprone inhibits the reaction [Iron results in increased activity of [CHUK protein binds to IKBKB protein]] CTD PMID:17172471 dexamethasone multiple interactions ISO Ikbkb (Mus musculus) 6480464 Dexamethasone inhibits the reaction [Ovalbumin results in increased phosphorylation of IKBKB protein] CTD PMID:36350155 dextran sulfate multiple interactions ISO Ikbkb (Mus musculus) 6480464 3 more ... CTD PMID:20155626 more ... dextran sulfate increases expression ISO Ikbkb (Mus musculus) 6480464 Dextran Sulfate results in increased expression of IKBKB protein modified form CTD PMID:25472953 dextran sulfate increases activity ISO Ikbkb (Mus musculus) 6480464 Dextran Sulfate results in increased activity of IKBKB protein CTD PMID:20155626 diarsenic trioxide decreases expression ISO IKBKB (Homo sapiens) 6480464 Arsenic Trioxide results in decreased expression of IKBKB mRNA and Arsenic Trioxide results in decreased expression of IKBKB protein CTD PMID:19763917 and PMID:22988968 diarsenic trioxide increases expression ISO IKBKB (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of IKBKB mRNA CTD PMID:29633893 diarsenic trioxide multiple interactions ISO IKBKB (Homo sapiens) 6480464 [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of IKBKB protein] which results in increased phosphorylation of and results in increased ubiquitination of and results in increased degradation of CCND1 protein more ... CTD PMID:22988968 and PMID:23949314 diclofenac multiple interactions EXP 6480464 Diclofenac inhibits the reaction [Freund's Adjuvant results in increased phosphorylation of IKBKB protein] CTD PMID:25935278 dimercaprol multiple interactions ISO IKBKB (Homo sapiens) 6480464 Dimercaprol inhibits the reaction [arsenite inhibits the reaction [4' more ... CTD PMID:10967126 dimethyl fumarate multiple interactions ISO IKBKB (Homo sapiens) 6480464 Dimethyl Fumarate inhibits the reaction [IKBKB protein results in increased expression of CCL2 mRNA] and Dimethyl Fumarate inhibits the reaction [IKBKB protein results in increased expression of TNF mRNA] CTD PMID:26683377 dimethylarsinic acid increases expression EXP 6480464 Cacodylic Acid results in increased expression of IKBKB protein CTD PMID:26617437 dioxygen multiple interactions ISO IKBKB (Homo sapiens) 6480464 3 more ... CTD PMID:23452621 dioxygen increases expression ISO IKBKB (Homo sapiens) 6480464 Oxygen deficiency results in increased expression of IKBKB mRNA CTD PMID:23452621 dipyridamole multiple interactions ISO Ikbkb (Mus musculus) 6480464 Dipyridamole inhibits the reaction [Lipopolysaccharides results in increased activity of IKBKB protein] CTD PMID:16765938 doxorubicin increases phosphorylation ISO IKBKB (Homo sapiens) 6480464 Doxorubicin results in increased phosphorylation of IKBKB protein CTD PMID:18463201 doxorubicin increases expression EXP 6480464 Doxorubicin results in increased expression of IKBKB protein CTD PMID:26036690 doxorubicin multiple interactions EXP 6480464 carvedilol inhibits the reaction [Doxorubicin results in increased expression of IKBKB protein] and febuxostat inhibits the reaction [Doxorubicin results in increased expression of IKBKB protein] CTD PMID:26036690 doxorubicin multiple interactions ISO IKBKB (Homo sapiens) 6480464 IKBKB gene mutant form inhibits the reaction [Doxorubicin results in increased degradation of NFKBIA protein] and Simvastatin promotes the reaction [Doxorubicin results in increased phosphorylation of IKBKB protein] CTD PMID:15899819 and PMID:18463201 elemental carbon multiple interactions ISO IKBKB (Homo sapiens) 6480464 [Air Pollutants results in increased abundance of [Carbon co-treated with Particulate Matter]] which results in increased expression of IKBKB mRNA more ... CTD PMID:31268311 elemental selenium multiple interactions ISO Ikbkb (Mus musculus) 6480464 Selenium inhibits the reaction [lipopolysaccharide and Escherichia coli O111 B4 results in increased activity of IKBKB protein] CTD PMID:17439952 elemental selenium multiple interactions ISO IKBKB (Homo sapiens) 6480464 [Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in increased expression of IKBKB mRNA CTD PMID:21481475 emamectin benzoate multiple interactions ISO IKBKB (Homo sapiens) 6480464 emamectin benzoate results in increased expression of and affects the localization of IKBKB protein CTD PMID:36269090 endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of IKBKB mRNA CTD PMID:29391264 enzyme inhibitor multiple interactions ISO IKBKB (Homo sapiens) 6480464 [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of IKBKB protein CTD PMID:23301498 ethanol multiple interactions ISO Ikbkb (Mus musculus) 6480464 Ethanol affects the expression of and affects the splicing of IKBKB mRNA CTD PMID:30319688 etoposide affects response to substance ISO Ikbkb (Mus musculus) 6480464 IKBKB protein affects the susceptibility to Etoposide CTD PMID:20159942 etoposide decreases expression ISO IKBKB (Homo sapiens) 6480464 Etoposide results in decreased expression of IKBKB protein CTD PMID:30177839 etoposide multiple interactions ISO IKBKB (Homo sapiens) 6480464 DAPK1 protein promotes the reaction [Etoposide results in decreased expression of IKBKB protein] more ... CTD PMID:30177839 eugenol multiple interactions EXP 6480464 Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of IKBKB protein] CTD PMID:19851710 Evodiamine multiple interactions ISO IKBKB (Homo sapiens) 6480464 evodiamine inhibits the reaction [TNF protein results in increased activity of IKBKB protein] CTD PMID:15710601 febuxostat multiple interactions EXP 6480464 Febuxostat inhibits the reaction [Doxorubicin results in increased expression of IKBKB protein] CTD PMID:26036690 filipin III multiple interactions EXP 6480464 Filipin inhibits the reaction [ferrous sulfate results in increased activity of [CHUK protein binds to IKBKB protein]] and Filipin inhibits the reaction [Iron results in increased activity of [CHUK protein binds to IKBKB protein]] CTD PMID:17172471 flavonoids increases expression EXP 6480464 Flavonoids results in increased expression of IKBKB mRNA CTD PMID:18035473 fluorescein 5-isothiocyanate affects binding ISO IKBKB (Homo sapiens) 6480464 Fluorescein-5-isothiocyanate binds to IKBKB protein CTD PMID:27129696 folic acid multiple interactions ISO Ikbkb (Mus musculus) 6480464 Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of IKBKB mRNA] CTD PMID:22206623 folic acid decreases expression ISO Ikbkb (Mus musculus) 6480464 Folic Acid results in decreased expression of IKBKB mRNA CTD PMID:25629700 folpet decreases expression ISO Ikbkb (Mus musculus) 6480464 folpet results in decreased expression of IKBKB mRNA CTD PMID:31558096 fructose increases phosphorylation EXP 6480464 Fructose results in increased phosphorylation of IKBKB protein CTD PMID:24491314 fructose multiple interactions EXP 6480464 Allopurinol inhibits the reaction [Fructose results in increased phosphorylation of IKBKB protein] and Quercetin inhibits the reaction [Fructose results in increased phosphorylation of IKBKB protein] CTD PMID:24491314 fulvestrant multiple interactions ISO IKBKB (Homo sapiens) 6480464 fulvestrant promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of IKBKB protein] CTD PMID:26220752 Fusaric acid decreases phosphorylation ISO IKBKB (Homo sapiens) 6480464 Fusaric Acid results in decreased phosphorylation of IKBKB protein CTD PMID:30582969 gallic acid multiple interactions ISO IKBKB (Homo sapiens) 6480464 Gallic Acid inhibits the reaction [TNF protein results in increased phosphorylation of IKBKB protein] CTD PMID:21420233 genistein increases expression EXP 6480464 Genistein results in increased expression of IKBKB mRNA CTD PMID:17010207 genistein multiple interactions ISO IKBKB (Homo sapiens) 6480464 Genistein inhibits the reaction [Oxygen deficiency results in increased expression of IKBKB mRNA] CTD PMID:23452621 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of IKBKB mRNA CTD PMID:22061828 and PMID:33387578 gentamycin multiple interactions ISO Ikbkb (Mus musculus) 6480464 [Gentamicins co-treated with Vancomycin co-treated with Cefoxitin co-treated with Metronidazole] inhibits the reaction [Fluorides results in increased expression of IKBKB mRNA] CTD PMID:37269894 ginsenoside Re multiple interactions ISO Ikbkb (Mus musculus) 6480464 ginsenoside Re inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of IKBKB protein] CTD PMID:22849695 glucose multiple interactions EXP 6480464 IKBKB affects the reaction [IL1B protein inhibits the reaction [Glucose results in increased expression of INS2 mRNA alternative form]] more ... CTD PMID:22558381 glucose multiple interactions ISO Ikbkb (Mus musculus) 6480464 IKBKB protein affects the reaction [Particulate Matter promotes the reaction [Glucose results in increased secretion of INS1 protein]] CTD PMID:31095431 glutathione multiple interactions ISO Ikbkb (Mus musculus) 6480464 GCLC protein inhibits the reaction [IKBKB protein mutant form results in decreased abundance of Glutathione] more ... CTD PMID:17067557 and PMID:20159942 glutathione affects abundance ISO Ikbkb (Mus musculus) 6480464 IKBKB protein affects the abundance of Glutathione CTD PMID:20159942 homoeriodictyol multiple interactions ISO Ikbkb (Mus musculus) 6480464 homoeriodictyol inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of IKBKB protein] CTD PMID:31850465 hydrogen peroxide affects response to substance ISO Ikbkb (Mus musculus) 6480464 IKBKB protein affects the susceptibility to Hydrogen Peroxide CTD PMID:20159942 hydrogen peroxide multiple interactions ISO IKBKB (Homo sapiens) 6480464 IKBKB protein affects the reaction [Hydrogen Peroxide results in increased expression of MMP9 mRNA] CTD PMID:26514923 hydrogen peroxide multiple interactions ISO Ikbkb (Mus musculus) 6480464 Hydrogen Peroxide inhibits the reaction [Melitten inhibits the reaction [Nitroprusside results in increased activity of IKBKB protein]] CTD PMID:17067557 hydroquinone multiple interactions ISO Ikbkb (Mus musculus) 6480464 hydroquinone inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of IKBKB protein] CTD PMID:20054000 ibrutinib multiple interactions ISO IKBKB (Homo sapiens) 6480464 (+)-JQ1 compound promotes the reaction [ibrutinib results in decreased activity of IKBKB protein] and ibrutinib promotes the reaction [(+)-JQ1 compound results in decreased activity of IKBKB protein] CTD PMID:25049379 ibrutinib decreases activity ISO IKBKB (Homo sapiens) 6480464 ibrutinib results in decreased activity of IKBKB protein CTD PMID:25049379 indole-3-methanol multiple interactions ISO IKBKB (Homo sapiens) 6480464 indole-3-carbinol inhibits the reaction [TNF protein results in increased activity of IKBKB protein] CTD PMID:15811958 indometacin increases expression EXP 6480464 Indomethacin results in increased expression of IKBKB mRNA and Indomethacin results in increased expression of IKBKB protein CTD PMID:23892052 iron atom multiple interactions EXP 6480464 deferiprone inhibits the reaction [Iron results in increased activity of [CHUK protein binds to IKBKB protein]] more ... CTD PMID:17172471 iron(0) multiple interactions EXP 6480464 deferiprone inhibits the reaction [Iron results in increased activity of [CHUK protein binds to IKBKB protein]] more ... CTD PMID:17172471 iron(2+) sulfate (anhydrous) multiple interactions EXP 6480464 deferiprone inhibits the reaction [ferrous sulfate results in increased activity of [CHUK protein binds to IKBKB protein]] more ... CTD PMID:17172471 Isorhapontigenin affects activity EXP 6480464 isorhapontigenin affects the activity of IKBKB protein CTD PMID:15607907 L-1,4-dithiothreitol multiple interactions ISO IKBKB (Homo sapiens) 6480464 Dithiothreitol inhibits the reaction [3 more ... CTD PMID:20584749 L-1,4-dithiothreitol multiple interactions ISO Ikbkb (Mus musculus) 6480464 Dithiothreitol inhibits the reaction [Melitten binds to and results in decreased activity of IKBKB protein] and Dithiothreitol inhibits the reaction [Melitten inhibits the reaction [Nitroprusside results in increased activity of IKBKB protein]] CTD PMID:17067557 lipopolysaccharide multiple interactions ISO IKBKB (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of IKBKB protein] more ... CTD PMID:18789402 more ... lipopolysaccharide increases expression EXP 6480464 Lipopolysaccharides results in increased expression of IKBKB mRNA and Lipopolysaccharides results in increased expression of IKBKB protein CTD PMID:17594812 and PMID:28070109 lipopolysaccharide increases phosphorylation ISO Ikbkb (Mus musculus) 6480464 Lipopolysaccharides results in increased phosphorylation of IKBKB protein CTD PMID:18789402 more ... lipopolysaccharide increases expression ISO Ikbkb (Mus musculus) 6480464 Lipopolysaccharides results in increased expression of IKBKB protein CTD PMID:18786831 lipopolysaccharide increases degradation ISO Ikbkb (Mus musculus) 6480464 Lipopolysaccharides results in increased degradation of IKBKB protein CTD PMID:17541474 lipopolysaccharide increases activity ISO Ikbkb (Mus musculus) 6480464 Lipopolysaccharides results in increased activity of IKBKB protein CTD PMID:16765938 more ... lipopolysaccharide increases phosphorylation EXP 6480464 Lipopolysaccharides results in increased phosphorylation of IKBKB protein CTD PMID:21893401 and PMID:25557508 lipopolysaccharide multiple interactions EXP 6480464 Apigenin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of IKBKB protein] more ... CTD PMID:17594812 more ... lipopolysaccharide multiple interactions ISO Ikbkb (Mus musculus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of IKBKB protein] more ... CTD PMID:10820281 more ... lipopolysaccharide increases phosphorylation ISO IKBKB (Homo sapiens) 6480464 Lipopolysaccharides results in increased phosphorylation of IKBKB protein CTD PMID:18789402 more ... lipopolysaccharide increases expression ISO IKBKB (Homo sapiens) 6480464 Lipopolysaccharides results in increased expression of IKBKB protein CTD PMID:21877189 LY294002 multiple interactions ISO Ikbkb (Mus musculus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of IKBKB protein] CTD PMID:18789402 LY294002 multiple interactions ISO IKBKB (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of IKBKB protein] CTD PMID:18789402 manganese atom multiple interactions ISO Ikbkb (Mus musculus) 6480464 IKBKB gene mutant form results in increased susceptibility to [manganese chloride results in increased abundance of Manganese] CTD PMID:32692843 manganese atom multiple interactions ISO IKBKB (Homo sapiens) 6480464 [manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of IKBKB protein more ... CTD PMID:34310962 manganese(0) multiple interactions ISO Ikbkb (Mus musculus) 6480464 IKBKB gene mutant form results in increased susceptibility to [manganese chloride results in increased abundance of Manganese] CTD PMID:32692843 manganese(0) multiple interactions ISO IKBKB (Homo sapiens) 6480464 [manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of IKBKB protein more ... CTD PMID:34310962 manganese(II) chloride multiple interactions ISO Ikbkb (Mus musculus) 6480464 IKBKB gene mutant form results in increased susceptibility to [manganese chloride results in increased abundance of Manganese] CTD PMID:32692843 manganese(II) chloride multiple interactions ISO IKBKB (Homo sapiens) 6480464 [manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of IKBKB protein more ... CTD PMID:34310962 mangiferin multiple interactions ISO IKBKB (Homo sapiens) 6480464 mangiferin inhibits the reaction [TNF protein results in increased phosphorylation of IKBKB protein] CTD PMID:21420233 mangiferin multiple interactions EXP 6480464 mangiferin inhibits the reaction [Galactosamine results in increased phosphorylation of IKBKB protein] CTD PMID:22310181 melittin multiple interactions ISO Ikbkb (Mus musculus) 6480464 Dithiothreitol inhibits the reaction [Melitten binds to and results in decreased activity of IKBKB protein] more ... CTD PMID:17067557 melittin affects binding ISO Ikbkb (Mus musculus) 6480464 Melitten binds to IKBKB protein CTD PMID:17067557 melittin multiple interactions ISO IKBKB (Homo sapiens) 6480464 Melitten inhibits the reaction [Nitroprusside results in increased activity of IKBKB protein] CTD PMID:17067557 metformin multiple interactions ISO IKBKB (Homo sapiens) 6480464 [Paclitaxel co-treated with Metformin] results in decreased expression of IKBKB mRNA CTD PMID:29309887 methapyrilene decreases methylation ISO IKBKB (Homo sapiens) 6480464 Methapyrilene results in decreased methylation of IKBKB intron CTD PMID:30157460 methapyrilene decreases expression EXP 6480464 Methapyrilene results in decreased expression of IKBKB mRNA CTD PMID:30467583 methoxyacetic acid increases expression EXP 6480464 methoxyacetic acid results in increased expression of IKBKB mRNA CTD PMID:20864626 methoxychlor affects methylation EXP 6480464 Methoxychlor affects the methylation of IKBKB gene CTD PMID:35440735 methylmercury chloride increases expression EXP 6480464 methylmercuric chloride results in increased expression of IKBKB mRNA CTD PMID:20864626 metronidazole multiple interactions ISO Ikbkb (Mus musculus) 6480464 [Gentamicins co-treated with Vancomycin co-treated with Cefoxitin co-treated with Metronidazole] inhibits the reaction [Fluorides results in increased expression of IKBKB mRNA] CTD PMID:37269894 miquelianin multiple interactions ISO IKBKB (Homo sapiens) 6480464 quercetin 3-O-glucuronide inhibits the reaction [Palmitates results in increased phosphorylation of IKBKB protein] CTD PMID:23504962 Monobutylphthalate increases expression EXP 6480464 monobutyl phthalate results in increased expression of IKBKB mRNA CTD PMID:20864626 Monobutylphthalate increases phosphorylation ISO Ikbkb (Mus musculus) 6480464 monobutyl phthalate results in increased phosphorylation of IKBKB protein CTD PMID:26745512 monosodium L-glutamate increases phosphorylation ISO Ikbkb (Mus musculus) 6480464 Sodium Glutamate results in increased phosphorylation of IKBKB protein CTD PMID:19800637 monosodium L-glutamate multiple interactions ISO Ikbkb (Mus musculus) 6480464 Atorvastatin inhibits the reaction [Sodium Glutamate results in increased phosphorylation of IKBKB protein] CTD PMID:19800637 monotropein multiple interactions ISO Ikbkb (Mus musculus) 6480464 monotropein inhibits the reaction [Lipopolysaccharides results in increased activity of IKBKB protein] CTD PMID:23261679 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine multiple interactions ISO Ikbkb (Mus musculus) 6480464 N more ... CTD PMID:16818790 N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide multiple interactions ISO Ikbkb (Mus musculus) 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of IKBKB mRNA] CTD PMID:17407152 N-[3,5-bis(trifluoromethyl)phenyl]-5-chloro-2-hydroxybenzamide multiple interactions ISO IKBKB (Homo sapiens) 6480464 [N-(3 and 5-bis(trifluoromethyl)phenyl)-5-chloro-2-hydroxybenzamide results in decreased activity of IKBKB protein] which results in decreased susceptibility to Copper CTD PMID:19747488 N-[3,5-bis(trifluoromethyl)phenyl]-5-chloro-2-hydroxybenzamide multiple interactions ISO Ikbkb (Mus musculus) 6480464 N-(3 and 5-bis(trifluoromethyl)phenyl)-5-chloro-2-hydroxybenzamide inhibits the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in increased expression of IKBKB mRNA] CTD PMID:25358444 N-acetyl-L-cysteine decreases activity ISO IKBKB (Homo sapiens) 6480464 Acetylcysteine results in decreased activity of IKBKB protein CTD PMID:17395010 N-acetyl-L-cysteine multiple interactions ISO IKBKB (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of IKBKB protein] CTD PMID:34310962 N-methyl-N'-nitro-N-nitrosoguanidine multiple interactions EXP 6480464 Eugenol inhibits the reaction [Methylnitronitrosoguanidine results in increased expression of IKBKB protein] CTD PMID:19851710 N-methyl-N'-nitro-N-nitrosoguanidine increases expression EXP 6480464 Methylnitronitrosoguanidine results in increased expression of IKBKB protein CTD PMID:19851710 N-nitrosodiethylamine multiple interactions ISO Ikbkb (Mus musculus) 6480464 Butylated Hydroxyanisole inhibits the reaction [IKBKB protein inhibits the reaction [Diethylnitrosamine results in increased activity of MAPK8 protein]] more ... CTD PMID:18691550 N-nitrosodiethylamine decreases response to substance ISO Ikbkb (Mus musculus) 6480464 IKBKB protein results in decreased susceptibility to Diethylnitrosamine CTD PMID:18691550 and PMID:19171122 N-nitrosodiethylamine affects response to substance ISO Ikbkb (Mus musculus) 6480464 IKBKB gene affects the susceptibility to Diethylnitrosamine CTD PMID:15989949 neratinib decreases expression ISO IKBKB (Homo sapiens) 6480464 neratinib results in decreased expression of IKBKB protein CTD PMID:22242139 nickel dichloride affects response to substance ISO Ikbkb (Mus musculus) 6480464 IKBKB affects the susceptibility to nickel chloride CTD PMID:16982623 nickel dichloride increases phosphorylation ISO IKBKB (Homo sapiens) 6480464 nickel chloride results in increased phosphorylation of IKBKB protein CTD PMID:30016632 nickel dichloride multiple interactions ISO IKBKB (Homo sapiens) 6480464 chrysin inhibits the reaction [nickel chloride results in increased phosphorylation of IKBKB protein] more ... CTD PMID:21466819 and PMID:30016632 nickel dichloride multiple interactions ISO Ikbkb (Mus musculus) 6480464 IKBKB affects the reaction [nickel chloride results in increased activity of PTGS2 promoter] CTD PMID:16982623 niclosamide affects localization ISO IKBKB (Homo sapiens) 6480464 Niclosamide affects the localization of IKBKB protein CTD PMID:26116531 nitroprusside multiple interactions ISO IKBKB (Homo sapiens) 6480464 Bee Venoms inhibits the reaction [Nitroprusside results in increased activity of IKBKB protein] and Melitten inhibits the reaction [Nitroprusside results in increased activity of IKBKB protein] CTD PMID:17067557 nitroprusside increases activity ISO Ikbkb (Mus musculus) 6480464 Nitroprusside results in increased activity of IKBKB protein CTD PMID:17067557 nitroprusside multiple interactions ISO Ikbkb (Mus musculus) 6480464 Bee Venoms inhibits the reaction [Nitroprusside results in increased activity of IKBKB protein] more ... CTD PMID:17067557 nitroprusside increases activity ISO IKBKB (Homo sapiens) 6480464 Nitroprusside results in increased activity of IKBKB protein CTD PMID:17067557 Nonylphenol increases expression EXP 6480464 nonylphenol results in increased expression of IKBKB mRNA CTD PMID:17010207 Nonylphenol increases phosphorylation EXP 6480464 nonylphenol results in increased phosphorylation of IKBKB protein CTD PMID:35998786 Nonylphenol increases phosphorylation ISO IKBKB (Homo sapiens) 6480464 nonylphenol results in increased phosphorylation of IKBKB protein CTD PMID:35998786 notoginsenoside R1 multiple interactions ISO Ikbkb (Mus musculus) 6480464 notoginsenoside R1 inhibits the reaction [Dextran Sulfate results in increased expression of IKBKB protein modified form] CTD PMID:25472953 o-anisidine affects expression ISO IKBKB (Homo sapiens) 6480464 2-anisidine affects the expression of IKBKB mRNA CTD PMID:28089782 ozone multiple interactions ISO IKBKB (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of and results in increased oxidation of IKBKB mRNA more ... CTD PMID:21621609 and PMID:32699268 ozone multiple interactions ISO Ikbkb (Mus musculus) 6480464 [SFTPA2 protein co-treated with Ozone] results in decreased expression of IKBKB mRNA and Ozone promotes the reaction [Soot results in increased phosphorylation of IKBKB protein] CTD PMID:27570198 and PMID:29202868 ozone increases phosphorylation EXP 6480464 Ozone results in increased phosphorylation of IKBKB protein CTD PMID:33383130 paclitaxel affects response to substance ISO Ikbkb (Mus musculus) 6480464 IKBKB protein affects the susceptibility to Paclitaxel CTD PMID:20159942 paclitaxel multiple interactions ISO IKBKB (Homo sapiens) 6480464 [Paclitaxel co-treated with Metformin] results in decreased expression of IKBKB mRNA CTD PMID:29309887 Paeonol multiple interactions ISO Ikbkb (Mus musculus) 6480464 [paeonol inhibits the reaction [[CHUK protein binds to IKBKB protein] which results in increased degradation of NFKBIA protein]] which affects the localization of NFKB1 protein more ... CTD PMID:22542583 paracetamol decreases expression ISO IKBKB (Homo sapiens) 6480464 Acetaminophen results in decreased expression of IKBKB mRNA CTD PMID:21420995 parthenolide multiple interactions ISO IKBKB (Homo sapiens) 6480464 parthenolide inhibits the reaction [Simvastatin results in increased phosphorylation of IKBKB protein] CTD PMID:18463201 perfluorooctane-1-sulfonic acid multiple interactions ISO Ikbkb (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of IKBKB mRNA CTD PMID:36331819 phenobarbital affects expression ISO Ikbkb (Mus musculus) 6480464 Phenobarbital affects the expression of IKBKB mRNA CTD PMID:23091169 phenylephrine increases activity EXP 6480464 Phenylephrine results in increased activity of IKBKB protein CTD PMID:11381115 phenylephrine multiple interactions EXP 6480464 IKBKB protein promotes the reaction [Phenylephrine results in increased expression of NPPA mRNA] CTD PMID:11381115 phorbol 13-acetate 12-myristate increases phosphorylation ISO IKBKB (Homo sapiens) 6480464 Tetradecanoylphorbol Acetate results in increased phosphorylation of IKBKB protein CTD PMID:26220752 phorbol 13-acetate 12-myristate multiple interactions ISO IKBKB (Homo sapiens) 6480464 3 more ... CTD PMID:20584749 more ... phorbol 13-acetate 12-myristate increases activity ISO IKBKB (Homo sapiens) 6480464 Tetradecanoylphorbol Acetate results in increased activity of IKBKB protein CTD PMID:20584749 phorbol 13-acetate 12-myristate increases activity ISO Ikbkb (Mus musculus) 6480464 Tetradecanoylphorbol Acetate results in increased activity of IKBKB protein CTD PMID:16474181 phorbol 13-acetate 12-myristate multiple interactions ISO Ikbkb (Mus musculus) 6480464 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of IKBKB protein] and resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of IKBKB protein] CTD PMID:16474181 pioglitazone decreases expression ISO IKBKB (Homo sapiens) 6480464 Pioglitazone results in decreased expression of IKBKB mRNA CTD PMID:32589349 platycodin D increases activity ISO IKBKB (Homo sapiens) 6480464 platycodin D results in increased activity of IKBKB protein CTD PMID:16631160 potassium chromate decreases expression ISO IKBKB (Homo sapiens) 6480464 potassium chromate(VI) results in decreased expression of IKBKB mRNA CTD PMID:22079256 potassium chromate multiple interactions ISO IKBKB (Homo sapiens) 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of IKBKB mRNA CTD PMID:22079256 progesterone increases expression ISO Ikbkb (Mus musculus) 6480464 Progesterone results in increased expression of IKBKB mRNA CTD PMID:21549006 protein kinase inhibitor multiple interactions ISO IKBKB (Homo sapiens) 6480464 [Protein Kinase Inhibitors results in decreased activity of IRAK4 protein] inhibits the reaction [resiquimod results in increased phosphorylation of IKBKB protein] CTD PMID:28924041 quercetin multiple interactions EXP 6480464 Quercetin inhibits the reaction [Fructose results in increased phosphorylation of IKBKB protein] and Quercetin inhibits the reaction [Rotenone results in increased expression of IKBKB mRNA] CTD PMID:24491314 and PMID:35337893 quercetin multiple interactions ISO Ikbkb (Mus musculus) 6480464 Quercetin inhibits the reaction [Lipopolysaccharides results in increased activity of IKBKB protein] CTD PMID:16171798 quercetin multiple interactions ISO IKBKB (Homo sapiens) 6480464 Quercetin inhibits the reaction [nickel chloride results in increased phosphorylation of IKBKB protein] and Quercetin inhibits the reaction [Palmitates results in increased phosphorylation of IKBKB protein] CTD PMID:23504962 and PMID:30016632 reactive oxygen species increases expression ISO IKBKB (Homo sapiens) 6480464 Reactive Oxygen Species results in increased expression of IKBKB mRNA CTD PMID:25800948 reactive oxygen species multiple interactions ISO Ikbkb (Mus musculus) 6480464 IKBKB protein inhibits the reaction [Diethylnitrosamine results in increased abundance of Reactive Oxygen Species] CTD PMID:18691550 resiquimod increases phosphorylation ISO IKBKB (Homo sapiens) 6480464 resiquimod results in increased phosphorylation of IKBKB protein CTD PMID:28924041 resiquimod multiple interactions ISO IKBKB (Homo sapiens) 6480464 2-((aminocarbonyl)amino)-5-(4-fluorophenyl)-3-thiophenecarboxamide promotes the reaction [resiquimod results in increased phosphorylation of IKBKB protein] and [Protein Kinase Inhibitors results in decreased activity of IRAK4 protein] inhibits the reaction [resiquimod results in increased phosphorylation of IKBKB protein] CTD PMID:28924041 resveratrol multiple interactions ISO Ikbkb (Mus musculus) 6480464 resveratrol inhibits the reaction [Dextran Sulfate results in increased activity of IKBKB protein] and resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of IKBKB protein] CTD PMID:16474181 and PMID:20155626 resveratrol multiple interactions ISO IKBKB (Homo sapiens) 6480464 [Plant Extracts co-treated with Resveratrol] results in increased expression of IKBKB mRNA and Resveratrol inhibits the reaction [Oxygen deficiency results in increased expression of IKBKB mRNA] CTD PMID:23452621 and PMID:23557933 resveratrol decreases phosphorylation ISO IKBKB (Homo sapiens) 6480464 resveratrol results in decreased phosphorylation of IKBKB protein CTD PMID:25692777 resveratrol decreases expression ISO Ikbkb (Mus musculus) 6480464 resveratrol results in decreased expression of IKBKB mRNA CTD PMID:19819963 resveratrol affects expression EXP 6480464 resveratrol affects the expression of IKBKB protein CTD PMID:17112897 rocaglamide decreases expression ISO IKBKB (Homo sapiens) 6480464 rocaglamide results in decreased expression of IKBKB protein CTD PMID:31433962 rotenone multiple interactions EXP 6480464 Catechin inhibits the reaction [Rotenone results in increased expression of IKBKB mRNA] and Quercetin inhibits the reaction [Rotenone results in increased expression of IKBKB mRNA] CTD PMID:35337893 rotenone increases expression EXP 6480464 Rotenone results in increased expression of IKBKB mRNA CTD PMID:35337893 SB 203580 multiple interactions ISO Ikbkb (Mus musculus) 6480464 SB 203580 inhibits the reaction [Lipopolysaccharides results in increased activity of IKBKB protein] CTD PMID:16765938 SB 203580 multiple interactions EXP 6480464 SB 203580 inhibits the reaction [sodium arsenite results in increased phosphorylation of IKBKB protein] CTD PMID:19616567 selenium atom multiple interactions ISO Ikbkb (Mus musculus) 6480464 Selenium inhibits the reaction [lipopolysaccharide and Escherichia coli O111 B4 results in increased activity of IKBKB protein] CTD PMID:17439952 selenium atom multiple interactions ISO IKBKB (Homo sapiens) 6480464 [Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in increased expression of IKBKB mRNA CTD PMID:21481475 selenomethionine affects expression ISO IKBKB (Homo sapiens) 6480464 Selenomethionine affects the expression of IKBKB mRNA CTD PMID:17222674 silicon dioxide increases expression ISO Ikbkb (Mus musculus) 6480464 Silicon Dioxide results in increased expression of IKBKB protein CTD PMID:32017981 silicon dioxide multiple interactions ISO Ikbkb (Mus musculus) 6480464 LIAS protein promotes the reaction [Silicon Dioxide results in increased expression of IKBKB protein] CTD PMID:32017981 simvastatin multiple interactions ISO IKBKB (Homo sapiens) 6480464 artemisinin inhibits the reaction [Simvastatin results in increased phosphorylation of IKBKB protein] more ... CTD PMID:18463201 simvastatin increases phosphorylation ISO IKBKB (Homo sapiens) 6480464 Simvastatin results in increased phosphorylation of IKBKB protein CTD PMID:18463201 simvastatin decreases expression ISO IKBKB (Homo sapiens) 6480464 Simvastatin results in decreased expression of IKBKB mRNA CTD PMID:17277159 sodium acetate trihydrate multiple interactions ISO Ikbkb (Mus musculus) 6480464 [Sodium Acetate co-treated with Butyric Acid co-treated with sodium propionate] inhibits the reaction [Fluorides results in increased expression of IKBKB mRNA] and [Sodium Acetate co-treated with Butyric Acid co-treated with sodium propionate] inhibits the reaction [Fluorides results in increased expression of IKBKB protein] CTD PMID:37269894 sodium arsenite affects response to substance ISO IKBKB (Homo sapiens) 6480464 IKBKB affects the susceptibility to sodium arsenite CTD PMID:20810208 sodium arsenite affects expression ISO IKBKB (Homo sapiens) 6480464 sodium arsenite affects the expression of IKBKB mRNA and sodium arsenite affects the expression of IKBKB protein CTD PMID:29528074 sodium arsenite multiple interactions ISO Ikbkb (Mus musculus) 6480464 [TRP53 gene mutant form affects the susceptibility to sodium arsenite] which results in decreased phosphorylation of IKBKB protein CTD PMID:29944914 sodium arsenite decreases expression ISO Ikbkb (Mus musculus) 6480464 sodium arsenite results in decreased expression of IKBKB mRNA CTD PMID:31233874 sodium arsenite increases phosphorylation EXP 6480464 sodium arsenite results in increased phosphorylation of IKBKB protein CTD PMID:19616567 sodium arsenite multiple interactions EXP 6480464 PS1145 inhibits the reaction [sodium arsenite results in increased phosphorylation of IKBKB protein] more ... CTD PMID:19616567 sodium arsenite increases activity ISO IKBKB (Homo sapiens) 6480464 sodium arsenite results in increased activity of IKBKB protein CTD PMID:23069812 sodium aurothiomalate multiple interactions ISO Ikbkb (Mus musculus) 6480464 Gold Sodium Thiomalate inhibits the reaction [Lipopolysaccharides results in increased activity of IKBKB protein] CTD PMID:10820281 sodium propionate multiple interactions ISO Ikbkb (Mus musculus) 6480464 [Sodium Acetate co-treated with Butyric Acid co-treated with sodium propionate] inhibits the reaction [Fluorides results in increased expression of IKBKB mRNA] and [Sodium Acetate co-treated with Butyric Acid co-treated with sodium propionate] inhibits the reaction [Fluorides results in increased expression of IKBKB protein] CTD PMID:37269894 Sodium salicylate multiple interactions ISO IKBKB (Homo sapiens) 6480464 Sodium Salicylate inhibits the reaction [Palmitates results in increased phosphorylation of IKBKB protein] CTD PMID:23504962 Sodium salicylate decreases expression ISO Ikbkb (Mus musculus) 6480464 Sodium Salicylate results in decreased expression of IKBKB protein modified form CTD PMID:21303813 sulfasalazine decreases expression ISO IKBKB (Homo sapiens) 6480464 Sulfasalazine results in decreased expression of IKBKB protein CTD PMID:15564333 sulfur dioxide multiple interactions ISO IKBKB (Homo sapiens) 6480464 [Air Pollutants results in increased abundance of [Particulate Matter co-treated with Carbon co-treated with Sulfur Dioxide co-treated with Nitrogen Oxides]] which results in increased expression of IKBKB mRNA CTD PMID:31268311 sulindac decreases activity ISO IKBKB (Homo sapiens) 6480464 Sulindac results in decreased activity of IKBKB protein CTD PMID:19526344 sulindac sulfide decreases activity ISO IKBKB (Homo sapiens) 6480464 sulindac sulfide results in decreased activity of IKBKB protein CTD PMID:11912124 sunitinib increases expression ISO IKBKB (Homo sapiens) 6480464 Sunitinib results in increased expression of IKBKB mRNA CTD PMID:31533062 taurine multiple interactions EXP 6480464 Taurine inhibits the reaction [sodium arsenite results in increased phosphorylation of IKBKB protein] CTD PMID:19616567 testosterone decreases expression ISO IKBKB (Homo sapiens) 6480464 Testosterone results in decreased expression of IKBKB mRNA CTD PMID:33359661 titanium dioxide increases expression ISO IKBKB (Homo sapiens) 6480464 titanium dioxide results in increased expression of IKBKB mRNA CTD PMID:22342292 titanium dioxide multiple interactions ISO Ikbkb (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of IKBKB mRNA CTD PMID:29950665 titanium dioxide increases expression ISO Ikbkb (Mus musculus) 6480464 titanium dioxide results in increased expression of IKBKB mRNA and titanium dioxide results in increased expression of IKBKB protein CTD PMID:28646487 more ... trans-anethole decreases activity ISO IKBKB (Homo sapiens) 6480464 anethole results in decreased activity of IKBKB protein CTD PMID:10871845 Triptolide decreases phosphorylation ISO Ikbkb (Mus musculus) 6480464 triptolide results in decreased phosphorylation of IKBKB protein CTD PMID:31618665 Triptolide multiple interactions ISO Ikbkb (Mus musculus) 6480464 TRP53 protein affects the reaction [triptolide results in decreased phosphorylation of IKBKB protein] CTD PMID:31618665 Triptolide decreases phosphorylation EXP 6480464 triptolide results in decreased phosphorylation of IKBKB protein CTD PMID:31618665 Triptolide multiple interactions EXP 6480464 pifithrin inhibits the reaction [triptolide results in decreased phosphorylation of IKBKB protein] CTD PMID:31618665 triptonide decreases expression ISO IKBKB (Homo sapiens) 6480464 triptonide results in decreased expression of IKBKB protein CTD PMID:31866380 triptonide increases expression ISO Ikbkb (Mus musculus) 6480464 triptonide results in increased expression of IKBKB mRNA CTD PMID:33045310 trovafloxacin decreases expression ISO Ikbkb (Mus musculus) 6480464 trovafloxacin results in decreased expression of IKBKB mRNA CTD PMID:35537566 tungsten decreases expression ISO Ikbkb (Mus musculus) 6480464 Tungsten results in decreased expression of IKBKB mRNA CTD PMID:30912803 umbelliferone multiple interactions EXP 6480464 7-hydroxycoumarin inhibits the reaction [Cisplatin results in increased expression of IKBKB protein] CTD PMID:33522649 valproic acid increases expression ISO Ikbkb (Mus musculus) 6480464 Valproic Acid results in increased expression of IKBKB mRNA CTD PMID:21427059 valproic acid decreases expression ISO IKBKB (Homo sapiens) 6480464 Valproic Acid results in decreased expression of IKBKB mRNA CTD PMID:29154799 vancomycin multiple interactions ISO Ikbkb (Mus musculus) 6480464 [Gentamicins co-treated with Vancomycin co-treated with Cefoxitin co-treated with Metronidazole] inhibits the reaction [Fluorides results in increased expression of IKBKB mRNA] CTD PMID:37269894 vincaleukoblastine increases phosphorylation ISO IKBKB (Homo sapiens) 6480464 Vinblastine results in increased phosphorylation of IKBKB protein CTD PMID:17029595 vincaleukoblastine multiple interactions ISO IKBKB (Homo sapiens) 6480464 Vinblastine results in decreased localization of [IKBKB protein binds to NFKBIA protein] CTD PMID:17029595 vorinostat decreases phosphorylation ISO IKBKB (Homo sapiens) 6480464 vorinostat results in decreased phosphorylation of IKBKB protein CTD PMID:17681667 vorinostat multiple interactions ISO IKBKB (Homo sapiens) 6480464 [vorinostat co-treated with TNFSF10 protein] results in decreased expression of IKBKB protein CTD PMID:16450389 wedelolactone decreases activity ISO IKBKB (Homo sapiens) 6480464 wedelolactone results in decreased activity of IKBKB protein CTD PMID:25450232 wedelolactone multiple interactions ISO IKBKB (Homo sapiens) 6480464 [wedelolactone results in decreased activity of IKBKB protein] which results in decreased phosphorylation of NFKBIA protein CTD PMID:25450232 zerumbone multiple interactions ISO IKBKB (Homo sapiens) 6480464 zerumbone inhibits the reaction [TNF protein results in increased activity of IKBKB protein] CTD PMID:16007145 zinc atom multiple interactions ISO IKBKB (Homo sapiens) 6480464 [Zinc results in increased localization of [IKBKB protein binds to NFKBIA protein]] which results in increased expression of BCL2 protein more ... CTD PMID:17029595 zinc atom affects expression ISO IKBKB (Homo sapiens) 6480464 Zinc affects the expression of IKBKB mRNA CTD PMID:16979875 zinc dichloride decreases expression ISO IKBKB (Homo sapiens) 6480464 zinc chloride results in decreased expression of IKBKB mRNA CTD PMID:21540303 zinc(0) multiple interactions ISO IKBKB (Homo sapiens) 6480464 [Zinc results in increased localization of [IKBKB protein binds to NFKBIA protein]] which results in increased expression of BCL2 protein more ... CTD PMID:17029595 zinc(0) affects expression ISO IKBKB (Homo sapiens) 6480464 Zinc affects the expression of IKBKB mRNA CTD PMID:16979875
