Golga2 (golgin A2) - Rat Genome Database

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Gene: Golga2 (golgin A2) Rattus norvegicus
Analyze
Symbol: Golga2
Name: golgin A2
RGD ID: 620282
Description: Enables importin-alpha family protein binding activity and protein kinase binding activity. Involved in several processes, including Golgi disassembly; mitotic spindle assembly; and protein homotetramerization. Located in Golgi apparatus and neuronal cell body. Part of protein-containing complex. Orthologous to human GOLGA2 (golgin A2); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 130 kDa cis-Golgi matrix protein; cis-Golgi matrix protein GM130; Gm130; golgi autoantigen, golgin subfamily a, 2; golgin subfamily A member 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2315,583,862 - 15,604,279 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl315,584,039 - 15,604,279 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx318,652,773 - 18,672,989 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0327,237,766 - 27,257,982 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0325,488,516 - 25,508,776 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0311,317,328 - 11,337,569 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl311,317,183 - 11,336,458 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0316,666,198 - 16,686,439 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4311,412,088 - 11,434,260 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1311,308,459 - 11,330,632 (+)NCBI
Celera310,328,596 - 10,348,889 (+)NCBICelera
Cytogenetic Map3p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. The p115-interactive proteins GM130 and giantin participate in endoplasmic reticulum-Golgi traffic. Alvarez C, etal., J Biol Chem. 2001 Jan 26;276(4):2693-700. Epub 2000 Oct 16.
2. ZFPL1, a novel ring finger protein required for cis-Golgi integrity and efficient ER-to-Golgi transport. Chiu CF, etal., EMBO J. 2008 Apr 9;27(7):934-47. doi: 10.1038/emboj.2008.40. Epub 2008 Mar 6.
3. Molecular characterization of two human autoantigens: unique cDNAs encoding 95- and 160-kD proteins of a putative family in the Golgi complex. Fritzler MJ, etal., J Exp Med. 1993 Jul 1;178(1):49-62.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. The palmitoyl transferase DHHC2 targets a dynamic membrane cycling pathway: regulation by a C-terminal domain. Greaves J, etal., Mol Biol Cell. 2011 Jun 1;22(11):1887-95. doi: 10.1091/mbc.E10-11-0924. Epub 2011 Apr 6.
6. GM130 is a parallel tetramer with a flexible rod-like structure and N-terminally open (Y-shaped) and closed (I-shaped) conformations. Ishida R, etal., FEBS J. 2015 Jun;282(11):2232-44. doi: 10.1111/febs.13271. Epub 2015 Apr 11.
7. Cdc2 kinase directly phosphorylates the cis-Golgi matrix protein GM130 and is required for Golgi fragmentation in mitosis. Lowe M, etal., Cell 1998 Sep 18;94(6):783-93.
8. The mitotic phosphorylation cycle of the cis-Golgi matrix protein GM130. Lowe M, etal., J Cell Biol. 2000 Apr 17;149(2):341-56.
9. The vesicle docking protein p115 binds GM130, a cis-Golgi matrix protein, in a mitotically regulated manner. Nakamura N, etal., Cell 1997 May 2;89(3):445-55.
10. Characterization of a cis-Golgi matrix protein, GM130. Nakamura N, etal., J Cell Biol 1995 Dec;131(6 Pt 2):1715-26.
11. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
12. YSK1 is activated by the Golgi matrix protein GM130 and plays a role in cell migration through its substrate 14-3-3zeta. Preisinger C, etal., J Cell Biol. 2004 Mar 29;164(7):1009-20. Epub 2004 Mar 22.
13. UBXD4, a UBX-containing protein, regulates the cell surface number and stability of alpha3-containing nicotinic acetylcholine receptors. Rezvani K, etal., J Neurosci. 2009 May 27;29(21):6883-96. doi: 10.1523/JNEUROSCI.4723-08.2009.
14. GOA pipeline RGD automated data pipeline
15. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
16. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
17. Comprehensive gene review and curation RGD comprehensive gene curation
18. Rab1 defines a novel pathway connecting the pre-Golgi intermediate compartment with the cell periphery. Sannerud R, etal., Mol Biol Cell. 2006 Apr;17(4):1514-26. Epub 2006 Jan 18.
19. Differential expression of otoferlin in brain, vestibular system, immature and mature cochlea of the rat. Schug N, etal., Eur J Neurosci. 2006 Dec;24(12):3372-80.
20. The role of the tethering proteins p115 and GM130 in transport through the Golgi apparatus in vivo. Seemann J, etal., Mol Biol Cell. 2000 Feb;11(2):635-45.
21. A GRASP55-rab2 effector complex linking Golgi structure to membrane traffic. Short B, etal., J Cell Biol. 2001 Dec 10;155(6):877-83. Epub 2001 Dec 10.
22. GRASP55, a second mammalian GRASP protein involved in the stacking of Golgi cisternae in a cell-free system. Shorter J, etal., EMBO J 1999 Sep 15;18(18):4949-60.
23. Sequential tethering of Golgins and catalysis of SNAREpin assembly by the vesicle-tethering protein p115. Shorter J, etal., J Cell Biol 2002 Apr 1;157(1):45-62.
24. SDF2L1 interacts with the ER-associated degradation machinery and retards the degradation of mutant proinsulin in pancreatic beta-cells. Tiwari A, etal., J Cell Sci. 2013 May 1;126(Pt 9):1962-8. doi: 10.1242/jcs.117374. Epub 2013 Feb 26.
25. Heterotypic tubular connections at the endoplasmic reticulum-Golgi complex interface. Vivero-Salmeron G, etal., Histochem Cell Biol. 2008 Oct;130(4):709-17. Epub 2008 Jul 22.
26. GM130 Regulates Golgi-Derived Spindle Assembly by Activating TPX2 and Capturing Microtubules. Wei JH, etal., Cell. 2015 Jul 16;162(2):287-99. doi: 10.1016/j.cell.2015.06.014. Epub 2015 Jul 9.
27. Direct targeting of cis-Golgi matrix proteins to the Golgi apparatus. Yoshimura SI, etal., J Cell Sci. 2001 Nov;114(Pt 22):4105-15.
Additional References at PubMed
PMID:8889548   PMID:11784862   PMID:12646573   PMID:14622145   PMID:14718562   PMID:14728599   PMID:15078902   PMID:15229288   PMID:15452145   PMID:15800058   PMID:16336229   PMID:16399995  
PMID:16413118   PMID:16489344   PMID:16778019   PMID:17003038   PMID:17036164   PMID:17046993   PMID:17204322   PMID:17314401   PMID:17488291   PMID:17724343   PMID:17765678   PMID:18045989  
PMID:18166528   PMID:18167358   PMID:19061864   PMID:19109421   PMID:19187565   PMID:19242490   PMID:19956733   PMID:20332113   PMID:20368623   PMID:20421892   PMID:20605918   PMID:20699666  
PMID:20943658   PMID:21111240   PMID:21187406   PMID:21300694   PMID:21525244   PMID:21552007   PMID:21606205   PMID:21640725   PMID:22735382   PMID:22792322   PMID:22802641   PMID:22841714  
PMID:23814182   PMID:23918928   PMID:23926254   PMID:24367100   PMID:24648492   PMID:25468996   PMID:26582200   PMID:27107012   PMID:27655914   PMID:29437892   PMID:29568061   PMID:30053369  


Genomics

Comparative Map Data
Golga2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2315,583,862 - 15,604,279 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl315,584,039 - 15,604,279 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx318,652,773 - 18,672,989 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0327,237,766 - 27,257,982 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0325,488,516 - 25,508,776 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0311,317,328 - 11,337,569 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl311,317,183 - 11,336,458 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0316,666,198 - 16,686,439 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4311,412,088 - 11,434,260 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1311,308,459 - 11,330,632 (+)NCBI
Celera310,328,596 - 10,348,889 (+)NCBICelera
Cytogenetic Map3p12NCBI
GOLGA2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389128,255,829 - 128,276,007 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9128,255,829 - 128,276,026 (-)EnsemblGRCh38hg38GRCh38
GRCh379131,018,108 - 131,038,286 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369130,057,929 - 130,078,089 (-)NCBINCBI36Build 36hg18NCBI36
Build 349128,097,662 - 128,117,822NCBI
Celera9101,669,012 - 101,689,172 (-)NCBICelera
Cytogenetic Map9q34.11NCBI
HuRef9100,631,562 - 100,651,722 (-)NCBIHuRef
CHM1_19131,169,131 - 131,189,291 (-)NCBICHM1_1
T2T-CHM13v2.09140,462,943 - 140,483,121 (-)NCBIT2T-CHM13v2.0
Golga2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39232,178,299 - 32,197,925 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl232,177,396 - 32,197,933 (+)EnsemblGRCm39 Ensembl
GRCm38232,288,287 - 32,307,913 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl232,287,384 - 32,307,921 (+)EnsemblGRCm38mm10GRCm38
MGSCv37232,143,773 - 32,163,441 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36232,109,393 - 32,129,930 (+)NCBIMGSCv36mm8
Celera231,992,729 - 32,012,412 (+)NCBICelera
Cytogenetic Map2BNCBI
cM Map222.09NCBI
Golga2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955570782,218 - 799,044 (-)NCBIChiLan1.0ChiLan1.0
GOLGA2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1911,079,657 - 11,099,108 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0999,376,847 - 99,397,128 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19128,045,805 - 128,065,200 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9128,047,056 - 128,065,137 (-)Ensemblpanpan1.1panPan2
GOLGA2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1955,234,836 - 55,251,698 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha954,429,688 - 54,446,610 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0956,156,848 - 56,173,782 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl956,156,862 - 56,173,777 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1954,916,750 - 54,933,678 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0955,231,389 - 55,248,316 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0955,322,893 - 55,339,826 (+)NCBIUU_Cfam_GSD_1.0
Golga2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947196,030,098 - 196,045,856 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493648715,798,623 - 15,814,360 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GOLGA2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11268,702,823 - 268,721,174 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21302,693,900 - 302,710,489 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GOLGA2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1129,852,442 - 9,873,536 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl129,852,461 - 9,873,767 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660796,359,761 - 6,380,755 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Golga2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247606,588,351 - 6,605,518 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Golga2
71 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:202
Count of miRNA genes:117
Interacting mature miRNAs:161
Transcripts:ENSRNOT00000016341
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70202Alc19Alcohol consumption QTL 192.5drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)3127494778Rat
631679Cm10Cardiac mass QTL 107.340.0001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3131158234Rat
631831Alc8Alcohol consumption QTL 82.7consumption behavior trait (VT:0002069)calculated ethanol drink intake rate (CMO:0001615)3133230976Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)diastolic blood pressure (CMO:0000005)3133278763Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)3133278763Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)pulse pressure (CMO:0000292)3133278763Rat
631545Bp85Blood pressure QTL 853.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3133278763Rat
4889966Bss95Bone structure and strength QTL 954.4tibia area (VT:1000281)tibia-fibula cross-sectional area (CMO:0001718)3136847613Rat
2312664Scl62Serum cholesterol level QTL 620.05blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)3138710544Rat
631568Bp92Blood pressure QTL 922.20.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3139874793Rat
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)3191609953Rat
1298526Arunc3Aerobic running capacity QTL 32.2exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)3822719433703538Rat
10401810Kidm53Kidney mass QTL 53kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3822719447233430Rat
70203Gcr2Gastric cancer resistance QTL 22.6stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)3865816227494778Rat
1358357Srcrtb1Stress Responsive Cort Basal QTL 16.360.002blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)3865816227494778Rat
6893355Bw101Body weight QTL 1010.40.38body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
6893363Bw105Body weight QTL 1052.60.0036body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
1558654Bw56Body weight QTL 564.50.0000171body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
70191BpQTLcluster4Blood pressure QTL cluster 43arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)31077870450302886Rat
70191BpQTLcluster4Blood pressure QTL cluster 43arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)31077870450302886Rat
1558647Cm46Cardiac mass QTL 465.40.0000055heart mass (VT:0007028)heart wet weight (CMO:0000069)31077882330356773Rat
1558650Cm48Cardiac mass QTL 4840.0001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)31077882330356773Rat
1558657Cm43Cardiac mass QTL 436.60.0000000293heart mass (VT:0007028)heart wet weight (CMO:0000069)31077882330356773Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)31086191289878372Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
2298542Neuinf11Neuroinflammation QTL 113.9nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)31500542276927699Rat

Markers in Region
RH128357  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2315,603,984 - 15,604,169 (+)MAPPERmRatBN7.2
Rnor_6.0311,337,275 - 11,337,459NCBIRnor6.0
Rnor_5.0316,686,145 - 16,686,329UniSTSRnor5.0
RGSC_v3.4311,433,970 - 11,434,154UniSTSRGSC3.4
Celera310,348,595 - 10,348,779UniSTS
RH 3.4 Map360.4UniSTS
Cytogenetic Map3p11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 56 40 19 40 8 11 74 35 41 11 8
Low 1 1 1
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_022596 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006233992 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006233993 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006233994 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006233995 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006233996 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006233997 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006233998 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592025 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105792 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105793 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105794 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105795 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105796 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105797 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA899518 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ746344 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FN805702 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FN805927 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ147221 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000115 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U35022 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000016341   ⟹   ENSRNOP00000016341
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl315,584,039 - 15,604,275 (+)Ensembl
Rnor_6.0 Ensembl311,317,328 - 11,336,379 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000091171   ⟹   ENSRNOP00000074890
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl315,584,075 - 15,604,279 (+)Ensembl
Rnor_6.0 Ensembl311,317,183 - 11,336,458 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000095262   ⟹   ENSRNOP00000080186
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl315,584,075 - 15,604,279 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000100279   ⟹   ENSRNOP00000087352
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl315,584,075 - 15,604,279 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000106907   ⟹   ENSRNOP00000078482
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl315,587,490 - 15,604,275 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000112704   ⟹   ENSRNOP00000079188
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl315,587,645 - 15,604,279 (+)Ensembl
RefSeq Acc Id: NM_022596   ⟹   NP_072118
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2315,584,039 - 15,604,279 (+)NCBI
Rnor_6.0311,317,328 - 11,337,569 (+)NCBI
Rnor_5.0316,666,198 - 16,686,439 (+)NCBI
RGSC_v3.4311,412,088 - 11,434,260 (+)RGD
Celera310,328,596 - 10,348,889 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006233992   ⟹   XP_006234054
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2315,583,862 - 15,604,279 (+)NCBI
Rnor_6.0311,317,351 - 11,336,373 (+)NCBI
Rnor_5.0316,666,198 - 16,686,439 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006233993   ⟹   XP_006234055
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2315,583,862 - 15,602,970 (+)NCBI
Rnor_6.0311,317,351 - 11,336,373 (+)NCBI
Rnor_5.0316,666,198 - 16,686,439 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006233994   ⟹   XP_006234056
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2315,583,862 - 15,604,279 (+)NCBI
Rnor_6.0311,317,351 - 11,336,373 (+)NCBI
Rnor_5.0316,666,198 - 16,686,439 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006233995   ⟹   XP_006234057
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2315,583,862 - 15,604,279 (+)NCBI
Rnor_6.0311,317,351 - 11,336,373 (+)NCBI
Rnor_5.0316,666,198 - 16,686,439 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006233996   ⟹   XP_006234058
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2315,583,862 - 15,604,279 (+)NCBI
Rnor_6.0311,317,351 - 11,336,373 (+)NCBI
Rnor_5.0316,666,198 - 16,686,439 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006233997   ⟹   XP_006234059
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2315,583,862 - 15,602,970 (+)NCBI
Rnor_6.0311,317,351 - 11,336,373 (+)NCBI
Rnor_5.0316,666,198 - 16,686,439 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006233998   ⟹   XP_006234060
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2315,584,045 - 15,603,449 (+)NCBI
Rnor_6.0311,317,351 - 11,336,373 (+)NCBI
Rnor_5.0316,666,198 - 16,686,439 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017592025   ⟹   XP_017447514
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2315,584,128 - 15,604,279 (+)NCBI
Rnor_6.0311,317,467 - 11,336,373 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039105792   ⟹   XP_038961720
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2315,583,862 - 15,602,970 (+)NCBI
RefSeq Acc Id: XM_039105793   ⟹   XP_038961721
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2315,583,862 - 15,604,279 (+)NCBI
RefSeq Acc Id: XM_039105794   ⟹   XP_038961722
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2315,583,862 - 15,602,970 (+)NCBI
RefSeq Acc Id: XM_039105795   ⟹   XP_038961723
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2315,583,862 - 15,602,970 (+)NCBI
RefSeq Acc Id: XM_039105796   ⟹   XP_038961724
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2315,583,862 - 15,602,970 (+)NCBI
RefSeq Acc Id: XM_039105797   ⟹   XP_038961725
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2315,584,247 - 15,604,279 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_072118   ⟸   NM_022596
- UniProtKB: A0A140TAB6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006234060   ⟸   XM_006233998
- Peptide Label: isoform X8
- UniProtKB: F1LSS0 (UniProtKB/Swiss-Prot),   Q62839 (UniProtKB/Swiss-Prot),   A6JU52 (UniProtKB/TrEMBL),   A0A140TAB6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006234054   ⟸   XM_006233992
- Peptide Label: isoform X1
- UniProtKB: A6JU51 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006234055   ⟸   XM_006233993
- Peptide Label: isoform X2
- UniProtKB: A0A0G2K977 (UniProtKB/TrEMBL),   A0A140TAB6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006234056   ⟸   XM_006233994
- Peptide Label: isoform X3
- UniProtKB: A0A140TAB6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006234058   ⟸   XM_006233996
- Peptide Label: isoform X5
- UniProtKB: A6JU51 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006234057   ⟸   XM_006233995
- Peptide Label: isoform X4
- UniProtKB: A0A140TAB6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006234059   ⟸   XM_006233997
- Peptide Label: isoform X6
- UniProtKB: A0A140TAB6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017447514   ⟸   XM_017592025
- Peptide Label: isoform X13
- UniProtKB: A0A140TAB6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000016341   ⟸   ENSRNOT00000016341
RefSeq Acc Id: ENSRNOP00000074890   ⟸   ENSRNOT00000091171
RefSeq Acc Id: XP_038961721   ⟸   XM_039105793
- Peptide Label: isoform X9
- UniProtKB: A6JU53 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038961720   ⟸   XM_039105792
- Peptide Label: isoform X7
- UniProtKB: A0A8I6G694 (UniProtKB/TrEMBL),   A6JU51 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038961722   ⟸   XM_039105794
- Peptide Label: isoform X10
- UniProtKB: A0A140TAB6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038961723   ⟸   XM_039105795
- Peptide Label: isoform X11
- UniProtKB: A6JU53 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038961724   ⟸   XM_039105796
- Peptide Label: isoform X12
- UniProtKB: A6JU53 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038961725   ⟸   XM_039105797
- Peptide Label: isoform X13
- UniProtKB: A0A140TAB6 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000080186   ⟸   ENSRNOT00000095262
RefSeq Acc Id: ENSRNOP00000078482   ⟸   ENSRNOT00000106907
RefSeq Acc Id: ENSRNOP00000087352   ⟸   ENSRNOT00000100279
RefSeq Acc Id: ENSRNOP00000079188   ⟸   ENSRNOT00000112704
Protein Domains
Golgin subfamily A conserved

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q62839-F1-model_v2 AlphaFold Q62839 1-998 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691981
Promoter ID:EPDNEW_R2506
Type:multiple initiation site
Name:Golga2_1
Description:golgin A2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0311,317,398 - 11,317,458EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620282 AgrOrtholog
BioCyc Gene G2FUF-50147 BioCyc
Ensembl Genes ENSRNOG00000011884 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000016341 ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOT00000091171 ENTREZGENE
  ENSRNOT00000091171.2 UniProtKB/TrEMBL
  ENSRNOT00000095262 ENTREZGENE
  ENSRNOT00000095262.1 UniProtKB/TrEMBL
  ENSRNOT00000100279 ENTREZGENE
  ENSRNOT00000100279.1 UniProtKB/TrEMBL
  ENSRNOT00000106907 ENTREZGENE
  ENSRNOT00000106907.1 UniProtKB/TrEMBL
  ENSRNOT00000112704 ENTREZGENE
  ENSRNOT00000112704.1 UniProtKB/TrEMBL
InterPro GM130_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GOLGA_cons_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Golgin_A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:64528 UniProtKB/Swiss-Prot
NCBI Gene 64528 ENTREZGENE
PANTHER GOLGIN SUBFAMILY A MEMBER 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10881 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam GM130_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GOLGA2L5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB GOLGA2 RGD
PhenoGen Golga2 PhenoGen
RatGTEx ENSRNOG00000011884 RatGTEx
UniProt A0A0G2K977 ENTREZGENE, UniProtKB/TrEMBL
  A0A140TAB6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZKX8_RAT UniProtKB/TrEMBL
  A0A8I5ZMK4_RAT UniProtKB/TrEMBL
  A0A8I6A5P6_RAT UniProtKB/TrEMBL
  A0A8I6G694 ENTREZGENE, UniProtKB/TrEMBL
  A6JU51 ENTREZGENE, UniProtKB/TrEMBL
  A6JU52 ENTREZGENE, UniProtKB/TrEMBL
  A6JU53 ENTREZGENE, UniProtKB/TrEMBL
  F1LSS0 ENTREZGENE
  GOGA2_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary F1LSS0 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-08-02 Golga2  golgin A2  Golga2  golgi autoantigen, golgin subfamily a, 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-22 Golga2  golgi autoantigen, golgin subfamily a, 2  Golga2  cis-Golgi matrix protein GM130  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Golga2  cis-Golgi matrix protein GM130  Gm130    Symbol and Name updated 1299863 APPROVED
2002-08-07 Gm130  cis-Golgi matrix protein GM130      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization localized to the cis-Golgi network 632909