Predicted to enable identical protein binding activity and single-stranded DNA binding activity. Predicted to be involved in double-strand break repair via homologous recombination; double-strand break repair via single-strand annealing; and mitotic recombination. Predicted to act upstream of or within DNA double-strand break processing involved in repair via single-strand annealing; cellular response to oxidative stress; and regulation of nucleotide-excision repair. Predicted to be part of protein-DNA complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in gastrointestinal system cancer (multiple); lung cancer (multiple); mucoepidermoid carcinoma; and nicotine dependence. Orthologous to human RAD52 (RAD52 homolog, DNA repair protein); PARTICIPATES IN homologous recombination pathway of double-strand break repair; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 6-propyl-2-thiouracil.
[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of RAD52 mRNA
[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of RAD52 mRNA
[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of RAD52 mRNA
[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of RAD52 mRNA
Identification of an SCLC susceptibility rs7963551 genetic polymorphism in a previously GWAS-identified 12p13.33 RAD52 lung cancer risk locus in the Chinese population.
Double-strand break repair and colorectal cancer: gene variants within 3' UTRs and microRNAs binding as modulators of cancer risk and clinical outcome.