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Gene: Trip13 (thyroid hormone receptor interactor 13) Rattus norvegicus

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Symbol:

Trip13

Name:

thyroid hormone receptor interactor 13

RGD ID:

1308516

Description:

Predicted to enable identical protein binding activity. Predicted to be involved in several processes, including double-strand break repair; meiosis I; and negative regulation of nuclear division. Predicted to act upstream of or within germ cell development and meiosis I. Predicted to be located in male germ cell nucleus. Predicted to be active in chromosome and nucleus. Human ortholog(s) of this gene implicated in mosaic variegated aneuploidy syndrome 3. Orthologous to human TRIP13 (thyroid hormone receptor interactor 13); INTERACTS WITH 1-naphthyl isothiocyanate; 3,3',4,4',5-pentachlorobiphenyl; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC292206; pachytene checkpoint protein 2 homolog; thyroid receptor-interacting protein 13; TR-interacting protein 13; TRIP-13

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TRIP13 (thyroid hormone receptor interactor 13)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Trip13 (thyroid hormone receptor interactor 13)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Trip13 (thyroid hormone receptor interactor 13)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	LOC129394329 (pachytene checkpoint protein 2 homolog)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TRIP13 (thyroid hormone receptor interactor 13)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Trip13 (thyroid hormone receptor interactor 13)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TRIP13 (thyroid hormone receptor interactor 13)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TRIP13 (thyroid hormone receptor interactor 13)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Trip13 (thyroid hormone receptor interactor 13)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	TRIP13 (thyroid hormone receptor interactor 13)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Trip13 (thyroid hormone receptor interactor 13)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	trip13 (thyroid hormone receptor interactor 13)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	PCH2	Alliance	DIOPT (InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	pch-2	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	pch2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	trip13	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	31,185,700 - 31,230,638 (+)	NCBI		GRCr8
mRatBN7.2	1	29,357,093 - 29,402,078 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	29,357,130 - 29,402,074 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	29,158,523 - 29,203,557 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	35,158,377 - 35,203,413 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	29,359,151 - 29,404,185 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	31,967,980 - 32,012,923 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	31,967,978 - 32,012,919 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	33,392,425 - 33,437,368 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	30,165,330 - 30,210,271 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	30,168,274 - 30,213,214 (+)	NCBI
Celera	1	28,006,108 - 28,051,038 (+)	NCBI		Celera
Cytogenetic Map	1	p11	NCBI

JBrowse:

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Model

Annotation Click to see Annotation Detail View

RGD Manual Disease Annotations Click to see Annotation Detail View

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Trip13	Rat	COVID-19		ISO	RGD:1318331	9068941	mRNA:increased expression:peripheral blood mononuclear cell (human)	RGD	PMID:32228226\|REF_RGD_ID:28912744

Imported Disease Annotations - ClinVar

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Trip13	Rat	autosomal dominant dyskeratosis congenita 2		ISO	RGD:1318331	8554872	ClinVar Annotator: match by term: Dyskeratosis congenita, autosomal dominant 2	ClinVar	PMID:12629597\|PMID:16247010\|PMID:17460043\|PMID:28492532
Trip13	Rat	dopamine transporter deficiency syndrome		ISO	RGD:1318331	8554872	ClinVar Annotator: match by term: Parkinsonism-dystonia, infantile	ClinVar	PMID:21112253\|PMID:28492532
Trip13	Rat	interstitial lung disease 2		ISO	RGD:1318331	8554872	ClinVar Annotator: match by term: Interstitial lung disease 2	ClinVar	PMID:12629597\|PMID:28492532
Trip13	Rat	mosaic variegated aneuploidy syndrome 3		ISO	RGD:1318331	8554872	ClinVar Annotator: match by term: Mosaic variegated aneuploidy syndrome 3 \| ClinVar Annotator: match by more ...	ClinVar	PMID:17576681\|PMID:25741868\|PMID:28492532\|PMID:28553959\|PMID:32473092\|PMID:35812326\|PMID:37340965\|PMID:9536098
Trip13	Rat	Oocyte/Zygote/Embryo Maturation Arrest 9		ISO	RGD:1318331	8554872	ClinVar Annotator: match by term: Oocyte maturation defect 9	ClinVar	PMID:25741868\|PMID:28492532\|PMID:29758562\|PMID:32473092\|PMID:35812326\|PMID:37340965

Imported Disease Annotations - CTD

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Trip13	Rat	Aneuploidy		ISO	RGD:1318331	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:28553959
Trip13	Rat	Germ Cell and Embryonal Neoplasms		ISO	RGD:1318331	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:28553959
Trip13	Rat	hepatocellular carcinoma		ISO	RGD:1318331	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:28284560
Trip13	Rat	mosaic variegated aneuploidy syndrome		ISO	RGD:1318331	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:28553959
Trip13	Rat	nephroblastoma		ISO	RGD:1318331	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:28553959

Imported Disease Annotations - OMIM

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Trip13	Rat	mosaic variegated aneuploidy syndrome 3		ISO	RGD:1318331	7240710		OMIM
Trip13	Rat	Oocyte/Zygote/Embryo Maturation Arrest 9		ISO	RGD:1318331	7240710		OMIM

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Trip13	Rat	(-)-epigallocatechin 3-gallate	multiple interactions	ISO	RGD:1318331	6480464	[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of TRIP13 mRNA	CTD	PMID:22079256
Trip13	Rat	1,1-dichloroethene	increases expression	ISO	RGD:1318332	6480464	vinylidene chloride results in increased expression of TRIP13 mRNA	CTD	PMID:26682919
Trip13	Rat	1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene	multiple interactions	ISO	RGD:1318332	6480464	[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ...	CTD	PMID:25510870
Trip13	Rat	1,2-dichloroethane	decreases expression	ISO	RGD:1318332	6480464	ethylene dichloride results in decreased expression of TRIP13 mRNA	CTD	PMID:28960355
Trip13	Rat	1-naphthyl isothiocyanate	increases expression	EXP		6480464	1-Naphthylisothiocyanate results in increased expression of TRIP13 mRNA	CTD	PMID:30723492
Trip13	Rat	17alpha-ethynylestradiol	increases expression	ISO	RGD:1318332	6480464	Ethinyl Estradiol results in increased expression of TRIP13 mRNA	CTD	PMID:17942748
Trip13	Rat	17alpha-ethynylestradiol	multiple interactions	ISO	RGD:1318332	6480464	[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of TRIP13 mRNA	CTD	PMID:17942748
Trip13	Rat	17beta-estradiol	increases expression	ISO	RGD:1318331	6480464	Estradiol results in increased expression of TRIP13 mRNA	CTD	PMID:16474171\|PMID:19167446
Trip13	Rat	2,2',4,4',5,5'-hexachlorobiphenyl	multiple interactions	ISO	RGD:1318332	6480464	[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ...	CTD	PMID:25510870
Trip13	Rat	2,2',5,5'-tetrachlorobiphenyl	multiple interactions	ISO	RGD:1318332	6480464	[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ...	CTD	PMID:25510870
Trip13	Rat	2,3,7,8-tetrachlorodibenzodioxine	multiple interactions	ISO	RGD:1318332	6480464	[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of TRIP13 mRNA	CTD	PMID:17942748
Trip13	Rat	2,3,7,8-tetrachlorodibenzodioxine	affects expression	ISO	RGD:1318331	6480464	Tetrachlorodibenzodioxin affects the expression of TRIP13 mRNA	CTD	PMID:22574217
Trip13	Rat	2,3,7,8-tetrachlorodibenzodioxine	increases expression	ISO	RGD:1318332	6480464	Tetrachlorodibenzodioxin results in increased expression of TRIP13 mRNA	CTD	PMID:19465110\|PMID:19770486
Trip13	Rat	2,3-dimethoxynaphthalene-1,4-dione	increases expression	ISO	RGD:1318331	6480464	2,3-dimethoxy-1,4-naphthoquinone results in increased expression of TRIP13 mRNA	CTD	PMID:17547211
Trip13	Rat	2,4,4'-trichlorobiphenyl	multiple interactions	ISO	RGD:1318332	6480464	[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ...	CTD	PMID:25510870
Trip13	Rat	2-palmitoylglycerol	increases expression	ISO	RGD:1318331	6480464	2-palmitoylglycerol results in increased expression of TRIP13 mRNA	CTD	PMID:37199045
Trip13	Rat	3,3',4,4',5-pentachlorobiphenyl	increases expression	EXP		6480464	3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TRIP13 mRNA	CTD	PMID:23196670
Trip13	Rat	3-methylcholanthrene	increases expression	ISO	RGD:1318332	6480464	Methylcholanthrene results in increased expression of TRIP13 mRNA	CTD	PMID:20713471
Trip13	Rat	4,4'-sulfonyldiphenol	increases expression	ISO	RGD:1318331	6480464	bisphenol S results in increased expression of TRIP13 mRNA	CTD	PMID:27685785
Trip13	Rat	4-hydroxynon-2-enal	decreases expression	ISO	RGD:1318332	6480464	4-hydroxy-2-nonenal results in decreased expression of TRIP13 mRNA	CTD	PMID:19191707
Trip13	Rat	4-hydroxynon-2-enal	increases expression	ISO	RGD:1318332	6480464	4-hydroxy-2-nonenal results in increased expression of TRIP13 mRNA	CTD	PMID:19191707
Trip13	Rat	6-propyl-2-thiouracil	increases expression	EXP		6480464	Propylthiouracil results in increased expression of TRIP13 mRNA	CTD	PMID:24780913
Trip13	Rat	acetamide	increases expression	EXP		6480464	acetamide results in increased expression of TRIP13 mRNA	CTD	PMID:31881176
Trip13	Rat	acetohydrazide	decreases expression	ISO	RGD:1318332	6480464	acetylhydrazine results in decreased expression of TRIP13 mRNA	CTD	PMID:15282401
Trip13	Rat	acrolein	multiple interactions	ISO	RGD:1318331	6480464	[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of more ...	CTD	PMID:32699268
Trip13	Rat	acrylamide	decreases expression	ISO	RGD:1318331	6480464	Acrylamide results in decreased expression of TRIP13 mRNA	CTD	PMID:32763439
Trip13	Rat	aflatoxin B1	affects expression	ISO	RGD:1318331	6480464	Aflatoxin B1 affects the expression of TRIP13 protein	CTD	PMID:20106945
Trip13	Rat	aflatoxin B1	multiple interactions	EXP		6480464	[sulforaphane co-treated with Aflatoxin B1] affects the expression of TRIP13 mRNA	CTD	PMID:25450479
Trip13	Rat	aflatoxin B1	increases expression	EXP		6480464	Aflatoxin B1 results in increased expression of TRIP13 mRNA	CTD	PMID:23630614
Trip13	Rat	all-trans-retinoic acid	decreases expression	ISO	RGD:1318331	6480464	Tretinoin results in decreased expression of TRIP13 mRNA	CTD	PMID:33167477
Trip13	Rat	alpha-pinene	multiple interactions	ISO	RGD:1318331	6480464	[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of more ...	CTD	PMID:32699268
Trip13	Rat	arsenite(3-)	decreases expression	ISO	RGD:1318332	6480464	arsenite results in decreased expression of TRIP13 mRNA	CTD	PMID:18929588
Trip13	Rat	arsenous acid	increases expression	ISO	RGD:1318331	6480464	Arsenic Trioxide results in increased expression of TRIP13 mRNA	CTD	PMID:17547211
Trip13	Rat	atrazine	decreases expression	ISO	RGD:1318331	6480464	Atrazine results in decreased expression of TRIP13 mRNA	CTD	PMID:22378314
Trip13	Rat	azathioprine	decreases expression	ISO	RGD:1318331	6480464	Azathioprine results in decreased expression of TRIP13 mRNA	CTD	PMID:22623647
Trip13	Rat	benzo[a]pyrene	increases expression	ISO	RGD:1318332	6480464	Benzo(a)pyrene results in increased expression of TRIP13 mRNA	CTD	PMID:20713471
Trip13	Rat	benzo[a]pyrene	increases expression	ISO	RGD:1318331	6480464	Benzo(a)pyrene results in increased expression of TRIP13 mRNA	CTD	PMID:32234424
Trip13	Rat	benzo[a]pyrene	decreases expression	ISO	RGD:1318332	6480464	Benzo(a)pyrene results in decreased expression of TRIP13 mRNA	CTD	PMID:19770486
Trip13	Rat	benzo[a]pyrene diol epoxide I	decreases expression	ISO	RGD:1318331	6480464	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of TRIP13 mRNA	CTD	PMID:20382639
Trip13	Rat	benzo[b]fluoranthene	increases expression	ISO	RGD:1318332	6480464	benzo(b)fluoranthene results in increased expression of TRIP13 mRNA	CTD	PMID:26377693
Trip13	Rat	bis(2-chloroethyl) sulfide	decreases expression	ISO	RGD:1318331	6480464	Mustard Gas results in decreased expression of TRIP13 mRNA	CTD	PMID:25102026
Trip13	Rat	bis(2-ethylhexyl) phthalate	decreases expression	ISO	RGD:1318332	6480464	Diethylhexyl Phthalate results in decreased expression of TRIP13 mRNA	CTD	PMID:34319233
Trip13	Rat	bisphenol A	increases expression	ISO	RGD:1318331	6480464	bisphenol A results in increased expression of TRIP13 mRNA	CTD	PMID:16474171
Trip13	Rat	bisphenol A	decreases expression	ISO	RGD:1318331	6480464	bisphenol A results in decreased expression of TRIP13 mRNA	CTD	PMID:29275510
Trip13	Rat	bisphenol A	increases expression	EXP		6480464	bisphenol A results in increased expression of TRIP13 mRNA	CTD	PMID:30816183\|PMID:32528016
Trip13	Rat	bisphenol A	decreases expression	EXP		6480464	bisphenol A results in decreased expression of TRIP13 mRNA	CTD	PMID:25181051
Trip13	Rat	cadmium dichloride	increases expression	ISO	RGD:1318331	6480464	Cadmium Chloride results in increased expression of TRIP13 mRNA	CTD	PMID:38382870
Trip13	Rat	calcitriol	multiple interactions	ISO	RGD:1318331	6480464	[Testosterone co-treated with Calcitriol] results in decreased expression of TRIP13 mRNA	CTD	PMID:21592394
Trip13	Rat	calcitriol	decreases expression	ISO	RGD:1318331	6480464	Calcitriol results in decreased expression of TRIP13 mRNA	CTD	PMID:21592394
Trip13	Rat	carbon nanotube	increases expression	ISO	RGD:1318332	6480464	Nanotubes, Carbon analog results in increased expression of TRIP13 mRNA; Nanotubes, Carbon results in increased more ...	CTD	PMID:25554681
Trip13	Rat	carbon nanotube	decreases expression	ISO	RGD:1318332	6480464	Nanotubes, Carbon results in decreased expression of TRIP13 mRNA	CTD	PMID:25620056
Trip13	Rat	chlorpyrifos	decreases expression	ISO	RGD:1318332	6480464	Chlorpyrifos results in decreased expression of TRIP13 mRNA	CTD	PMID:37019170
Trip13	Rat	chromium(6+)	multiple interactions	ISO	RGD:1318331	6480464	[zinc chromate results in increased abundance of chromium hexavalent ion] which results in decreased expression more ...	CTD	PMID:38479592
Trip13	Rat	cisplatin	affects response to substance	ISO	RGD:1318331	6480464	TRIP13 protein affects the susceptibility to Cisplatin	CTD	PMID:16217747
Trip13	Rat	cobalt dichloride	decreases expression	ISO	RGD:1318331	6480464	cobaltous chloride results in decreased expression of TRIP13 mRNA	CTD	PMID:19320972\|PMID:19376846
Trip13	Rat	copper atom	increases expression	ISO	RGD:1318332	6480464	Copper results in increased expression of TRIP13 mRNA	CTD	PMID:17205981
Trip13	Rat	copper(0)	increases expression	ISO	RGD:1318332	6480464	Copper results in increased expression of TRIP13 mRNA	CTD	PMID:17205981
Trip13	Rat	coumestrol	multiple interactions	ISO	RGD:1318331	6480464	[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of TRIP13 mRNA; [Coumestrol co-treated with resveratrol] more ...	CTD	PMID:19167446
Trip13	Rat	coumestrol	increases expression	ISO	RGD:1318331	6480464	Coumestrol results in increased expression of TRIP13 mRNA	CTD	PMID:19167446
Trip13	Rat	cyclosporin A	decreases expression	ISO	RGD:1318331	6480464	Cyclosporine results in decreased expression of TRIP13 mRNA	CTD	PMID:19159671\|PMID:25562108
Trip13	Rat	DDE	increases expression	ISO	RGD:1318331	6480464	Dichlorodiphenyl Dichloroethylene results in increased expression of TRIP13 mRNA	CTD	PMID:38568856
Trip13	Rat	diarsenic trioxide	increases expression	ISO	RGD:1318331	6480464	Arsenic Trioxide results in increased expression of TRIP13 mRNA	CTD	PMID:17547211
Trip13	Rat	diazinon	increases methylation	ISO	RGD:1318331	6480464	Diazinon results in increased methylation of TRIP13 gene	CTD	PMID:22964155
Trip13	Rat	dibenzo[a,l]pyrene	decreases expression	ISO	RGD:1318332	6480464	dibenzo(a,l)pyrene results in decreased expression of TRIP13 mRNA	CTD	PMID:25908611
Trip13	Rat	dibutyl phthalate	decreases expression	ISO	RGD:1318332	6480464	Dibutyl Phthalate results in decreased expression of TRIP13 mRNA	CTD	PMID:21266533
Trip13	Rat	dieldrin	increases expression	EXP		6480464	Dieldrin results in increased expression of TRIP13 mRNA	CTD	PMID:23153324
Trip13	Rat	diethyl maleate	increases expression	EXP		6480464	diethyl maleate results in increased expression of TRIP13 mRNA	CTD	PMID:21161181
Trip13	Rat	dioxygen	decreases expression	ISO	RGD:1318331	6480464	Oxygen deficiency results in decreased expression of TRIP13 mRNA	CTD	PMID:26516004
Trip13	Rat	Enterolactone	multiple interactions	ISO	RGD:1318331	6480464	[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of TRIP13 mRNA	CTD	PMID:19167446
Trip13	Rat	enzyme inhibitor	multiple interactions	ISO	RGD:1318331	6480464	[Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation more ...	CTD	PMID:23301498
Trip13	Rat	ethyl methanesulfonate	decreases expression	ISO	RGD:1318331	6480464	Ethyl Methanesulfonate results in decreased expression of TRIP13 mRNA	CTD	PMID:23649840
Trip13	Rat	folic acid	multiple interactions	ISO	RGD:1318331	6480464	[Folic Acid deficiency co-treated with Methotrexate] results in decreased expression of TRIP13 mRNA	CTD	PMID:24657277
Trip13	Rat	formaldehyde	decreases expression	ISO	RGD:1318331	6480464	Formaldehyde results in decreased expression of TRIP13 mRNA	CTD	PMID:23649840
Trip13	Rat	genistein	increases expression	ISO	RGD:1318331	6480464	Genistein results in increased expression of TRIP13 mRNA	CTD	PMID:16474171
Trip13	Rat	heptachlor	increases expression	EXP		6480464	Heptachlor results in increased expression of TRIP13 mRNA	CTD	PMID:23153324
Trip13	Rat	ivermectin	decreases expression	ISO	RGD:1318331	6480464	Ivermectin results in decreased expression of TRIP13 protein	CTD	PMID:32959892
Trip13	Rat	Lasiocarpine	increases expression	ISO	RGD:1318331	6480464	lasiocarpine results in increased expression of TRIP13 mRNA	CTD	PMID:32234424
Trip13	Rat	leflunomide	decreases expression	ISO	RGD:1318331	6480464	leflunomide results in decreased expression of TRIP13 mRNA	CTD	PMID:28988120
Trip13	Rat	lidocaine	increases expression	EXP		6480464	Lidocaine results in increased expression of TRIP13 mRNA	CTD	PMID:35283115
Trip13	Rat	linezolid	decreases expression	EXP		6480464	Linezolid results in decreased expression of TRIP13 mRNA	CTD	PMID:21296123
Trip13	Rat	mercury atom	increases expression	ISO	RGD:1318331	6480464	Mercury results in increased expression of TRIP13 mRNA	CTD	PMID:17547211
Trip13	Rat	mercury(0)	increases expression	ISO	RGD:1318331	6480464	Mercury results in increased expression of TRIP13 mRNA	CTD	PMID:17547211
Trip13	Rat	methotrexate	multiple interactions	ISO	RGD:1318331	6480464	[Folic Acid deficiency co-treated with Methotrexate] results in decreased expression of TRIP13 mRNA	CTD	PMID:24657277
Trip13	Rat	methyl methanesulfonate	decreases expression	ISO	RGD:1318331	6480464	Methyl Methanesulfonate results in decreased expression of TRIP13 mRNA	CTD	PMID:23649840
Trip13	Rat	mirex	increases expression	EXP		6480464	Mirex results in increased expression of TRIP13 mRNA	CTD	PMID:23153324
Trip13	Rat	N-nitrosodiethylamine	increases expression	ISO	RGD:1318332	6480464	Diethylnitrosamine results in increased expression of TRIP13 mRNA	CTD	PMID:17854601
Trip13	Rat	N-nitrosodiethylamine	multiple interactions	ISO	RGD:1318332	6480464	RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of TRIP13 mRNA]	CTD	PMID:17854601
Trip13	Rat	N-Nitrosopyrrolidine	decreases expression	ISO	RGD:1318331	6480464	N-Nitrosopyrrolidine results in decreased expression of TRIP13 mRNA	CTD	PMID:32234424
Trip13	Rat	nickel atom	increases expression	ISO	RGD:1318331	6480464	Nickel results in increased expression of TRIP13 mRNA	CTD	PMID:25583101
Trip13	Rat	niclosamide	decreases expression	ISO	RGD:1318331	6480464	Niclosamide results in decreased expression of TRIP13 mRNA	CTD	PMID:28284560
Trip13	Rat	okadaic acid	increases expression	ISO	RGD:1318331	6480464	Okadaic Acid results in increased expression of TRIP13 mRNA	CTD	PMID:38832940
Trip13	Rat	oxaliplatin	multiple interactions	EXP		6480464	[oxaliplatin co-treated with Topotecan] results in decreased expression of TRIP13 mRNA	CTD	PMID:25729387
Trip13	Rat	ozone	increases expression	ISO	RGD:1318332	6480464	Ozone results in increased expression of TRIP13 mRNA	CTD	PMID:25658374
Trip13	Rat	ozone	multiple interactions	ISO	RGD:1318331	6480464	[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of more ...	CTD	PMID:32699268
Trip13	Rat	ozone	multiple interactions	ISO	RGD:1318332	6480464	[Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased more ...	CTD	PMID:24381131\|PMID:25658374\|PMID:27106289\|PMID:34911549
Trip13	Rat	paracetamol	affects expression	ISO	RGD:1318332	6480464	Acetaminophen affects the expression of TRIP13 mRNA	CTD	PMID:17562736
Trip13	Rat	paracetamol	increases expression	ISO	RGD:1318331	6480464	Acetaminophen results in increased expression of TRIP13 mRNA	CTD	PMID:22230336
Trip13	Rat	PCB138	multiple interactions	ISO	RGD:1318332	6480464	[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ...	CTD	PMID:25510870
Trip13	Rat	perfluorooctanoic acid	decreases expression	ISO	RGD:1318331	6480464	perfluorooctanoic acid results in decreased expression of TRIP13 mRNA	CTD	PMID:36326898
Trip13	Rat	phenethyl isothiocyanate	decreases expression	ISO	RGD:1318331	6480464	phenethyl isothiocyanate results in decreased expression of TRIP13 mRNA	CTD	PMID:26678675
Trip13	Rat	phenobarbital	affects expression	ISO	RGD:1318332	6480464	Phenobarbital affects the expression of TRIP13 mRNA	CTD	PMID:23091169
Trip13	Rat	picoxystrobin	increases expression	ISO	RGD:1318331	6480464	picoxystrobin results in increased expression of TRIP13 mRNA	CTD	PMID:33512557
Trip13	Rat	pirinixic acid	multiple interactions	ISO	RGD:1318331	6480464	[pirinixic acid binds to and results in increased activity of PPARA protein] which results in more ...	CTD	PMID:19710929
Trip13	Rat	pirinixic acid	increases expression	ISO	RGD:1318332	6480464	pirinixic acid results in increased expression of TRIP13 mRNA	CTD	PMID:18445702\|PMID:23811191
Trip13	Rat	potassium chromate	multiple interactions	ISO	RGD:1318331	6480464	[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of TRIP13 mRNA	CTD	PMID:22079256
Trip13	Rat	potassium chromate	decreases expression	ISO	RGD:1318331	6480464	potassium chromate(VI) results in decreased expression of TRIP13 mRNA	CTD	PMID:22079256
Trip13	Rat	quercetin	affects expression	ISO	RGD:1318331	6480464	Quercetin affects the expression of TRIP13 mRNA	CTD	PMID:21632981
Trip13	Rat	resveratrol	multiple interactions	ISO	RGD:1318331	6480464	[Coumestrol co-treated with resveratrol] results in increased expression of TRIP13 mRNA	CTD	PMID:19167446
Trip13	Rat	resveratrol	increases expression	ISO	RGD:1318331	6480464	resveratrol results in increased expression of TRIP13 mRNA	CTD	PMID:19167446
Trip13	Rat	rotenone	increases expression	ISO	RGD:1318331	6480464	Rotenone results in increased expression of TRIP13 mRNA	CTD	PMID:33512557
Trip13	Rat	silicon dioxide	decreases expression	ISO	RGD:1318331	6480464	Silicon Dioxide analog results in decreased expression of TRIP13 mRNA	CTD	PMID:23806026
Trip13	Rat	silicon dioxide	increases expression	ISO	RGD:1318332	6480464	Silicon Dioxide results in increased expression of TRIP13 mRNA	CTD	PMID:29341224
Trip13	Rat	sodium arsenite	affects expression	ISO	RGD:1318331	6480464	sodium arsenite affects the expression of TRIP13 mRNA	CTD	PMID:29301061
Trip13	Rat	sodium arsenite	decreases expression	ISO	RGD:1318331	6480464	sodium arsenite results in decreased expression of TRIP13 mRNA; sodium arsenite results in decreased expression more ...	CTD	PMID:30528433\|PMID:38568856
Trip13	Rat	sodium arsenite	increases expression	ISO	RGD:1318331	6480464	sodium arsenite results in increased expression of TRIP13 mRNA	CTD	PMID:34032870
Trip13	Rat	sodium dichromate	increases expression	EXP		6480464	sodium bichromate results in increased expression of TRIP13 mRNA	CTD	PMID:25993096
Trip13	Rat	sodium fluoride	increases expression	ISO	RGD:1318332	6480464	Sodium Fluoride results in increased expression of TRIP13 protein	CTD	PMID:28918527
Trip13	Rat	sulforaphane	multiple interactions	EXP		6480464	[sulforaphane co-treated with Aflatoxin B1] affects the expression of TRIP13 mRNA	CTD	PMID:25450479
Trip13	Rat	sunitinib	decreases expression	ISO	RGD:1318331	6480464	Sunitinib results in decreased expression of TRIP13 mRNA	CTD	PMID:31533062
Trip13	Rat	tacrolimus hydrate	increases expression	ISO	RGD:1318332	6480464	Tacrolimus results in increased expression of TRIP13 mRNA	CTD	PMID:29362864
Trip13	Rat	testosterone	multiple interactions	ISO	RGD:1318331	6480464	[Testosterone co-treated with Calcitriol] results in decreased expression of TRIP13 mRNA	CTD	PMID:21592394
Trip13	Rat	testosterone	decreases expression	ISO	RGD:1318331	6480464	Testosterone results in decreased expression of TRIP13 mRNA	CTD	PMID:21592394
Trip13	Rat	tetrachloromethane	affects expression	ISO	RGD:1318332	6480464	Carbon Tetrachloride affects the expression of TRIP13 mRNA	CTD	PMID:17484886
Trip13	Rat	tetrachloromethane	increases expression	ISO	RGD:1318332	6480464	Carbon Tetrachloride results in increased expression of TRIP13 mRNA	CTD	PMID:31919559
Trip13	Rat	thioacetamide	increases expression	EXP		6480464	Thioacetamide results in increased expression of TRIP13 mRNA	CTD	PMID:23411599
Trip13	Rat	titanium dioxide	increases expression	ISO	RGD:1318332	6480464	titanium dioxide results in increased expression of TRIP13 mRNA	CTD	PMID:23557971
Trip13	Rat	titanium dioxide	decreases methylation	ISO	RGD:1318332	6480464	titanium dioxide results in decreased methylation of TRIP13 gene	CTD	PMID:35295148
Trip13	Rat	topotecan	multiple interactions	EXP		6480464	[oxaliplatin co-treated with Topotecan] results in decreased expression of TRIP13 mRNA	CTD	PMID:25729387
Trip13	Rat	trimellitic anhydride	increases expression	ISO	RGD:1318332	6480464	trimellitic anhydride results in increased expression of TRIP13 mRNA	CTD	PMID:19042947
Trip13	Rat	troglitazone	decreases expression	ISO	RGD:1318331	6480464	troglitazone results in decreased expression of TRIP13 mRNA	CTD	PMID:19140230
Trip13	Rat	trovafloxacin	decreases expression	ISO	RGD:1318332	6480464	trovafloxacin results in decreased expression of TRIP13 mRNA	CTD	PMID:35537566
Trip13	Rat	tunicamycin	decreases expression	ISO	RGD:1318331	6480464	Tunicamycin results in decreased expression of TRIP13 mRNA	CTD	PMID:29453283
Trip13	Rat	urethane	decreases expression	ISO	RGD:1318331	6480464	Urethane results in decreased expression of TRIP13 mRNA	CTD	PMID:28818685
Trip13	Rat	valproic acid	decreases expression	ISO	RGD:1318331	6480464	Valproic Acid results in decreased expression of TRIP13 mRNA	CTD	PMID:19101580
Trip13	Rat	valproic acid	affects expression	ISO	RGD:1318331	6480464	Valproic Acid affects the expression of TRIP13 mRNA	CTD	PMID:25979313
Trip13	Rat	zinc atom	increases expression	ISO	RGD:1318331	6480464	Zinc deficiency results in increased expression of TRIP13 mRNA	CTD	PMID:22171008
Trip13	Rat	zinc(0)	increases expression	ISO	RGD:1318331	6480464	Zinc deficiency results in increased expression of TRIP13 mRNA	CTD	PMID:22171008
Trip13	Rat	zoledronic acid	decreases expression	ISO	RGD:1318331	6480464	zoledronic acid results in decreased expression of TRIP13 mRNA	CTD	PMID:24714768

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Trip13	Rat	cell differentiation	involved_in	IEA	UniProtKB-KW:KW-0221	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Trip13	Rat	double-strand break repair	involved_in	ISO	RGD:1318332	1624291	PMID:20711356	RGD	PMID:20711356
Trip13	Rat	double-strand break repair	acts_upstream_of_or_within	IEA	UniProtKB:Q3UA06\|ensembl:ENSMUSP00000022053	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Trip13	Rat	double-strand break repair	acts_upstream_of_or_within	ISO	RGD:1318332	1624291	MGI:3719273 PMID:17696610	RGD	PMID:17696610
Trip13	Rat	double-strand break repair	involved_in	ISS	UniProtKB:Q3UA06	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Trip13	Rat	female meiosis I	acts_upstream_of_or_within	ISO	RGD:1318332	1624291	MGI:3719273 PMID:17696610	RGD	PMID:17696610
Trip13	Rat	female meiosis I	acts_upstream_of_or_within	IEA	UniProtKB:Q3UA06\|ensembl:ENSMUSP00000022053	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Trip13	Rat	male meiosis I	acts_upstream_of_or_within	ISO	RGD:1318332	1624291	MGI:3719273 PMID:17696610	RGD	PMID:17696610
Trip13	Rat	male meiosis I	acts_upstream_of_or_within	IEA	UniProtKB:Q3UA06\|ensembl:ENSMUSP00000022053	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Trip13	Rat	meiotic cell cycle	involved_in	IEA	UniRule:UR001683769	1600115	GO_REF:0000104	UniProt	GO_REF:0000104
Trip13	Rat	meiotic cell cycle	involved_in	IEA	UniProtKB-KW:KW-0469	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Trip13	Rat	meiotic recombination checkpoint signaling	involved_in	IBA	FB:FBgn0051453\|PANTHER:PTN000554401\|SGD:S000000390	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Trip13	Rat	mitotic spindle assembly checkpoint signaling	involved_in	ISS	UniProtKB:Q15645	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Trip13	Rat	mitotic spindle assembly checkpoint signaling	involved_in	IEA	UniProtKB:Q15645\|ensembl:ENSP00000166345	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Trip13	Rat	mitotic spindle assembly checkpoint signaling	involved_in	ISO	RGD:1318331	1624291	PMID:28553959	RGD	PMID:28553959
Trip13	Rat	oocyte maturation	acts_upstream_of_or_within	ISO	RGD:1318332	1624291	MGI:1929645\|MGI:3719273 PMID:17696610	RGD	PMID:17696610
Trip13	Rat	oocyte maturation	acts_upstream_of_or_within	IEA	UniProtKB:Q3UA06\|ensembl:ENSMUSP00000022053	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Trip13	Rat	oogenesis	involved_in	ISS	UniProtKB:Q3UA06	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Trip13	Rat	oogenesis	involved_in	IEA	UniProtKB:Q3UA06\|ensembl:ENSMUSP00000022053	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Trip13	Rat	oogenesis	involved_in	ISO	RGD:1318332	1624291	PMID:20711356	RGD	PMID:20711356
Trip13	Rat	oogenesis	involved_in	IEA	UniProtKB-KW:KW-0896	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Trip13	Rat	reciprocal meiotic recombination	involved_in	ISS	UniProtKB:Q3UA06	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Trip13	Rat	reciprocal meiotic recombination	acts_upstream_of_or_within	IEA	UniProtKB:Q3UA06\|ensembl:ENSMUSP00000022053	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Trip13	Rat	reciprocal meiotic recombination	acts_upstream_of_or_within	ISO	RGD:1318332	1624291	MGI:3719273 PMID:17696610	RGD	PMID:17696610
Trip13	Rat	reciprocal meiotic recombination	involved_in	IBA	MGI:1916966\|PANTHER:PTN000554401\|SGD:S000000390\|TAIR:locus:2121939\|UniProtKB:Q7XK25	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Trip13	Rat	reciprocal meiotic recombination	involved_in	ISO	RGD:1318332	1624291	PMID:20711356	RGD	PMID:20711356
Trip13	Rat	reciprocal meiotic recombination	involved_in	IEA	UniRule:UR001683769	1600115	GO_REF:0000104	UniProt	GO_REF:0000104
Trip13	Rat	spermatid development	acts_upstream_of_or_within	ISO	RGD:1318332	1624291	MGI:3719273 PMID:17696610	RGD	PMID:17696610
Trip13	Rat	spermatid development	acts_upstream_of_or_within	IEA	UniProtKB:Q3UA06\|ensembl:ENSMUSP00000022053	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Trip13	Rat	spermatogenesis	involved_in	ISO	RGD:1318332	1624291	PMID:20711356	RGD	PMID:20711356
Trip13	Rat	spermatogenesis	involved_in	IEA	UniProtKB:Q3UA06\|ensembl:ENSMUSP00000022053	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Trip13	Rat	spermatogenesis	involved_in	IEA	UniProtKB-KW:KW-0744	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Trip13	Rat	spermatogenesis	involved_in	IEA	UniRule:UR001683769	1600115	GO_REF:0000104	UniProt	GO_REF:0000104
Trip13	Rat	spermatogenesis	involved_in	ISS	UniProtKB:Q3UA06	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Trip13	Rat	synaptonemal complex assembly	involved_in	ISS	UniProtKB:Q3UA06	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Trip13	Rat	synaptonemal complex assembly	involved_in	IEA	UniProtKB:Q3UA06\|ensembl:ENSMUSP00000022053	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Trip13	Rat	synaptonemal complex assembly	involved_in	ISO	RGD:1318332	1624291	PMID:20711356	RGD	PMID:20711356

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Trip13	Rat	chromosome	is_active_in	IBA	PANTHER:PTN000554401\|TAIR:locus:2121939\|UniProtKB:Q7XK25\|WB:WBGene00008641	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Trip13	Rat	male germ cell nucleus	located_in	ISO	RGD:1318332	1624291	PMID:17696610	RGD	PMID:17696610
Trip13	Rat	male germ cell nucleus	located_in	IEA	UniProtKB:Q3UA06\|ensembl:ENSMUSP00000022053	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Trip13	Rat	nucleus	located_in	IEA	UniProtKB-SubCell:SL-0191	1600115	GO_REF:0000044	UniProt	GO_REF:0000044
Trip13	Rat	nucleus	located_in	IEA	UniProtKB-KW:KW-0539	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Trip13	Rat	nucleus	is_active_in	IBA	MGI:1916966\|PANTHER:PTN000554401\|SGD:S000000390\|TAIR:locus:2121939\|UniProtKB:Q7XK25	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Trip13	Rat	nucleus	located_in	IEA	UniRule:UR001683769	1600115	GO_REF:0000104	UniProt	GO_REF:0000104

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Trip13	Rat	ATP binding	enables	IEA	UniProtKB-KW:KW-0067	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Trip13	Rat	ATP binding	enables	IEA	InterPro:IPR003959\|InterPro:IPR003960	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Trip13	Rat	ATP binding	enables	IEA	InterPro:IPR001270\|InterPro:IPR003959\|InterPro:IPR003960	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Trip13	Rat	ATP hydrolysis activity	enables	IEA	InterPro:IPR003959\|InterPro:IPR003960	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Trip13	Rat	ATP hydrolysis activity	enables	IEA	InterPro:IPR003593\|InterPro:IPR003959\|InterPro:IPR003960	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Trip13	Rat	identical protein binding	enables	ISO	RGD:1318331	1624291	UniProtKB:Q15645 PMID:16169070, PMID:16189514, PMID:25416956, PMID:32296183	RGD	PMID:16169070\|PMID:16189514\|PMID:25416956\|PMID:32296183
Trip13	Rat	identical protein binding	enables	IEA	UniProtKB:Q15645\|ensembl:ENSP00000166345	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Trip13	Rat	nucleotide binding	enables	IEA	UniProtKB-KW:KW-0547	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Trip13	Rat	protein binding	enables	ISO	RGD:1318331	1624291	UniProtKB:A0A0S2Z4I0\|UniProtKB:A0A0S2Z515\|UniProtKB:A0A0S2Z576\|UniProtKB:A6NJ78-4\|UniProtKB:O00560\|UniProtKB:O00746\|UniProtKB:O14531\|UniProtKB:O15389\|UniProtKB:O60260\|UniProtKB:O75935-2\|UniProtKB:O95231\|UniProtKB:O95630\|UniProtKB:O95865\|UniProtKB:P07902\|UniProtKB:P11473\|UniProtKB:P13693\|UniProtKB:P14784\|UniProtKB:P15289\|UniProtKB:P21964\|UniProtKB:P21964-2\|UniProtKB:P22307\|UniProtKB:P28062-2\|UniProtKB:P30039\|UniProtKB:P47897\|UniProtKB:P47897-2\|UniProtKB:P53672\|UniProtKB:P54646\|UniProtKB:P55771\|UniProtKB:P59990\|UniProtKB:P59991\|UniProtKB:P60329\|UniProtKB:P62875\|UniProtKB:P67775\|UniProtKB:P78317\|UniProtKB:Q0VD86\|UniProtKB:Q13214-2\|UniProtKB:Q13228\|UniProtKB:Q14689\|UniProtKB:Q14689-6\|UniProtKB:Q14847\|UniProtKB:Q14847-2\|UniProtKB:Q15013\|UniProtKB:Q15777\|UniProtKB:Q16773\|UniProtKB:Q3LI64\|UniProtKB:Q3LI66\|UniProtKB:Q53EP0-3\|UniProtKB:Q5BKX5-3\|UniProtKB:Q5W111\|UniProtKB:Q6BCY4\|UniProtKB:Q6BCY4-2\|UniProtKB:Q6P9B6\|UniProtKB:Q6PEX3\|UniProtKB:Q6PF18\|UniProtKB:Q6PIM4\|UniProtKB:Q7KZS0\|UniProtKB:Q86VF2-5\|UniProtKB:Q8IVS8\|UniProtKB:Q8N1A6\|UniProtKB:Q8N3C7\|UniProtKB:Q8NDV7\|UniProtKB:Q8TBB1\|UniProtKB:Q8TC57\|UniProtKB:Q8WXK3-2\|UniProtKB:Q92824-2\|UniProtKB:Q969Q4\|UniProtKB:Q96A09\|UniProtKB:Q96EZ4\|UniProtKB:Q96FA3\|UniProtKB:Q96G04\|UniProtKB:Q96HA8\|UniProtKB:Q96JB6\|UniProtKB:Q96L50\|UniProtKB:Q96LM6\|UniProtKB:Q9BQY4\|UniProtKB:Q9BSH5\|UniProtKB:Q9GZM7\|UniProtKB:Q9GZM7-3\|UniProtKB:Q9GZT8\|UniProtKB:Q9H0F6-2\|UniProtKB:Q9H0W9\|UniProtKB:Q9H0W9-3\|UniProtKB:Q9NRQ2\|UniProtKB:Q9NRY6\|UniProtKB:Q9NTN9\|UniProtKB:Q9NTN9-3\|UniProtKB:Q9NXR5-2\|UniProtKB:Q9NZ81\|UniProtKB:Q9UBX5\|UniProtKB:Q9UJ78-2\|UniProtKB:Q9Y2V0\|UniProtKB:Q9Y303\|UniProtKB:Q9Y303-2\|UniProtKB:Q9Y4F5-3 PMID:16169070, PMID:16189514, PMID:19060904, PMID:21516116, PMID:24722188, PMID:25416956, PMID:25910212, PMID:26871637, PMID:29892012, PMID:31515488, PMID:32296183	RGD	PMID:16169070\|PMID:16189514\|PMID:19060904\|PMID:21516116\|PMID:24722188\|PMID:25416956\|PMID:25910212\|PMID:26871637\|PMID:29892012\|PMID:31515488\|PMID:32296183
Trip13	Rat	protein binding	enables	ISO	RGD:1318332	1624291	UniProtKB:Q99LG4 PMID:28256593	RGD	PMID:28256593

Disease Annotations Click to see Annotation Detail View

Aneuploidy (ISO)

autosomal dominant dyskeratosis congenita 2 (ISO)

COVID-19 (ISO)

dopamine transporter deficiency syndrome (ISO)

Germ Cell and Embryonal Neoplasms (ISO)

hepatocellular carcinoma (ISO)

interstitial lung disease 2 (ISO)

mosaic variegated aneuploidy syndrome (ISO)

mosaic variegated aneuploidy syndrome 3 (ISO)

nephroblastoma (ISO)

Oocyte/Zygote/Embryo Maturation Arrest 9 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

1,1-dichloroethene (ISO)

1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ISO)

1,2-dichloroethane (ISO)

1-naphthyl isothiocyanate (EXP)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,3-dimethoxynaphthalene-1,4-dione (ISO)

2,4,4'-trichlorobiphenyl (ISO)

2-palmitoylglycerol (ISO)

3,3',4,4',5-pentachlorobiphenyl (EXP)

3-methylcholanthrene (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxynon-2-enal (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

acetohydrazide (ISO)

acrolein (ISO)

acrylamide (ISO)

aflatoxin B1 (EXP,ISO)

all-trans-retinoic acid (ISO)

alpha-pinene (ISO)

arsenite(3-) (ISO)

arsenous acid (ISO)

atrazine (ISO)

azathioprine (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

benzo[b]fluoranthene (ISO)

bis(2-chloroethyl) sulfide (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

cadmium dichloride (ISO)

calcitriol (ISO)

carbon nanotube (ISO)

chlorpyrifos (ISO)

chromium(6+) (ISO)

cisplatin (ISO)

cobalt dichloride (ISO)

copper atom (ISO)

copper(0) (ISO)

coumestrol (ISO)

cyclosporin A (ISO)

DDE (ISO)

diarsenic trioxide (ISO)

diazinon (ISO)

dibenzo[a,l]pyrene (ISO)

dibutyl phthalate (ISO)

dieldrin (EXP)

diethyl maleate (EXP)

dioxygen (ISO)

Enterolactone (ISO)

enzyme inhibitor (ISO)

ethyl methanesulfonate (ISO)

folic acid (ISO)

formaldehyde (ISO)

genistein (ISO)

heptachlor (EXP)

ivermectin (ISO)

Lasiocarpine (ISO)

leflunomide (ISO)

lidocaine (EXP)

linezolid (EXP)

mercury atom (ISO)

mercury(0) (ISO)

methotrexate (ISO)

methyl methanesulfonate (ISO)

mirex (EXP)

N-nitrosodiethylamine (ISO)

N-Nitrosopyrrolidine (ISO)

nickel atom (ISO)

niclosamide (ISO)

okadaic acid (ISO)

oxaliplatin (EXP)

ozone (ISO)

paracetamol (ISO)

PCB138 (ISO)

perfluorooctanoic acid (ISO)

phenethyl isothiocyanate (ISO)

phenobarbital (ISO)

picoxystrobin (ISO)

pirinixic acid (ISO)

potassium chromate (ISO)

quercetin (ISO)

resveratrol (ISO)

rotenone (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

sodium dichromate (EXP)

sodium fluoride (ISO)

sulforaphane (EXP)

sunitinib (ISO)

tacrolimus hydrate (ISO)

testosterone (ISO)

tetrachloromethane (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

topotecan (EXP)

trimellitic anhydride (ISO)

troglitazone (ISO)

trovafloxacin (ISO)

tunicamycin (ISO)

urethane (ISO)

valproic acid (ISO)

zinc atom (ISO)

zinc(0) (ISO)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell differentiation (IEA)

double-strand break repair (IEA,ISO,ISS)

female meiosis I (IEA,ISO)

male meiosis I (IEA,ISO)

meiotic cell cycle (IEA)

meiotic recombination checkpoint signaling (IBA)

mitotic spindle assembly checkpoint signaling (IEA,ISO,ISS)

oocyte maturation (IEA,ISO)

oogenesis (IEA,ISO,ISS)

reciprocal meiotic recombination (IBA,IEA,ISO,ISS)

spermatid development (IEA,ISO)

spermatogenesis (IEA,ISO,ISS)

synaptonemal complex assembly (IEA,ISO,ISS)

Cellular Component

chromosome (IBA)

male germ cell nucleus (IEA,ISO)

nucleus (IBA,IEA)

Molecular Function

ATP binding (IEA)

ATP hydrolysis activity (IEA)

identical protein binding (IEA,ISO)

nucleotide binding (IEA)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	GOA pipeline	RGD automated data pipeline
5.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:11591653	PMID:12477932	PMID:15489334	PMID:16169070	PMID:16189514	PMID:17696610	PMID:20711356	PMID:25416956	PMID:28553959

Genomics

Comparative Map Data

Trip13
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	31,185,700 - 31,230,638 (+)	NCBI		GRCr8
mRatBN7.2	1	29,357,093 - 29,402,078 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	29,357,130 - 29,402,074 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	29,158,523 - 29,203,557 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	35,158,377 - 35,203,413 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	29,359,151 - 29,404,185 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	31,967,980 - 32,012,923 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	31,967,978 - 32,012,919 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	33,392,425 - 33,437,368 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	30,165,330 - 30,210,271 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	30,168,274 - 30,213,214 (+)	NCBI
Celera	1	28,006,108 - 28,051,038 (+)	NCBI		Celera
Cytogenetic Map	1	p11	NCBI

TRIP13
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	892,884 - 919,348 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	892,884 - 919,357 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	5	892,999 - 918,235 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	946,004 - 971,160 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	5	946,003 - 971,158	NCBI
Celera	5	934,119 - 956,942 (+)	NCBI		Celera
Cytogenetic Map	5	p15.33	NCBI
HuRef	5	878,510 - 902,319 (+)	NCBI		HuRef
CHM1_1	5	892,681 - 916,387 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	5	798,936 - 824,664 (+)	NCBI		T2T-CHM13v2.0

Trip13
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	13	74,060,577 - 74,085,855 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	13	74,059,466 - 74,085,903 (-)	Ensembl		GRCm39 Ensembl
GRCm38	13	73,912,450 - 73,937,795 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	13	73,911,347 - 73,937,784 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	13	74,049,910 - 74,075,215 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	13	74,377,349 - 74,403,784 (-)	NCBI		MGSCv36	mm8
Celera	13	76,242,042 - 76,267,349 (-)	NCBI		Celera
Cytogenetic Map	13	C1	NCBI
cM Map	13	40.15	NCBI

Trip13
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955504	434,159 - 452,671 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955504	434,187 - 452,636 (+)	NCBI	ChiLan1.0	ChiLan1.0

LOC129394329
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	18	62,747,149 - 62,752,803 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	16	68,664,916 - 68,671,423 (+)	NCBI		NHGRI_mPanPan1

TRIP13
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	34	11,522,940 - 11,539,885 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	34	11,522,940 - 11,539,885 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	34	16,033,842 - 16,050,187 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	34	11,424,655 - 11,441,021 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	34	11,424,655 - 11,441,021 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	34	11,475,417 - 11,491,720 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	34	11,455,172 - 11,471,463 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	34	11,665,947 - 11,682,409 (-)	NCBI		UU_Cfam_GSD_1.0

Trip13
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	244,572,199 - 244,584,096 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936815	734,167 - 745,092 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936815	734,029 - 745,381 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TRIP13
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	16	79,458,847 - 79,473,712 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	16	79,458,843 - 79,473,705 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

TRIP13
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	4	737,214 - 760,263 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	4	737,263 - 760,171 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666054	35,288,652 - 35,311,359 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Trip13
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624751	439,119 - 459,080 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624751	439,195 - 459,033 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Trip13
191 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	230
Count of miRNA genes:	168
Interacting mature miRNAs:	184
Transcripts:	ENSRNOT00000021532
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631688	Hcas2	Hepatocarcinoma susceptibility QTL 2	3	0.0001	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	5925874	115540829	Rat
1357397	Bw41	Body weight QTL 41	4.19	0.0001	body mass (VT:0001259)	body weight (CMO:0000012)	1	22340647	49361612	Rat
1578650	Bmd6	Bone mineral density QTL 6	12.2		femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	1	509108	43284926	Rat
1578651	Bmd7	Bone mineral density QTL 7	14.2		femur mineral mass (VT:0010011)	compact volumetric bone mineral density (CMO:0001730)	1	509108	43284926	Rat
2313062	Bmd73	Bone mineral density QTL 73	3.9	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	1	11481312	82174945	Rat
1554320	Bmd1	Bone mineral density QTL 1	12.2	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	1	509108	86060548	Rat
2313065	Bss67	Bone structure and strength QTL 67	3.1	0.0001	tibia area (VT:1000281)	tibia total energy absorbed before break (CMO:0001736)	1	11481312	82174945	Rat
7421626	Bp360	Blood pressure QTL 360		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	4393289	49393289	Rat
1357400	Bw62	Body weight QTL62	4.05		inguinal fat pad mass (VT:0010424)	inguinal fat pad weight to body weight ratio (CMO:0001253)	1	22340647	67340647	Rat
2313070	Bss52	Bone structure and strength QTL 52	4.4	0.0001	body length (VT:0001256)	body length (CMO:0000013)	1	1	32356093	Rat
1357401	Bw43	Body weight QTL 43	3.75		body mass (VT:0001259)	body weight (CMO:0000012)	1	22340647	49361612	Rat
2313069	Bss68	Bone structure and strength QTL 68	2.9	0.0001	tibia size trait (VT:0100001)	tibia total energy absorbed before break (CMO:0001736)	1	11481312	82174945	Rat
631495	Bp96	Blood pressure QTL 96	4.52		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	22340647	102268831	Rat
631494	Bp95	Blood pressure QTL 95	40	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	16206210	49268520	Rat
2313075	Bss66	Bone structure and strength QTL 66	3.4	0.0001	tibia length (VT:0004357)	tibia length (CMO:0000450)	1	11481312	82174945	Rat
5684998	Bss101	Bone structure and strength QTL 101	3.6		tibia strength trait (VT:1000284)	tibia ultimate force (CMO:0001734)	1	15431621	49361612	Rat
5684999	Bss102	Bone structure and strength QTL 102	5.5	7e-07	tibia strength trait (VT:1000284)	tibia stiffness (CMO:0001735)	1	15431621	49361612	Rat
1300167	Hrtrt2	Heart rate QTL 2	4.35		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	1	11481312	75088344	Rat
2313077	Bss69	Bone structure and strength QTL 69	3.5	0.0001	tibia strength trait (VT:1000284)	bone polar moment of inertia (CMO:0001558)	1	11481312	82174945	Rat
2317755	Glom22	Glomerulus QTL 22	3.8		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	1	11481482	32355910	Rat
1578756	Iddm22	Insulin dependent diabetes mellitus QTL 22	2.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	11835181	56835181	Rat
631508	Sald1	Serum aldosterone level QTL 1	3.7		blood aldosterone amount (VT:0005346)	serum aldosterone level (CMO:0000487)	1	9856001	54856001	Rat
1331785	Rf27	Renal function QTL 27	4.643		urine sodium amount (VT:0006274)	urine sodium level (CMO:0000129)	1	28879780	78430678	Rat
2313090	Bmd69	Bone mineral density QTL 69	4.4	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	1	1	32356093	Rat
724520	Bp145	Blood pressure QTL 145	2.1	0.0024	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	20784828	65784828	Rat
1558642	Prcr2	Prostate cancer resistance QTL 2	4.3		prostate integrity trait (VT:0010571)	area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)	1	20763158	44095856	Rat
2313092	Bmd72	Bone mineral density QTL 72	2.5	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	1	11481312	82174945	Rat
2313097	Bss70	Bone structure and strength QTL 70	3.5	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	1	11481312	82174945	Rat
738020	Pia8	Pristane induced arthritis QTL 8	4.7		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	1	1	65833076	Rat
1600360	Mcs16	Mammary carcinoma susceptibility QTL 16	2.4		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	1	2244390	43433040	Rat
1578669	Bss9	Bone structure and strength QTL 9	6.3		femur morphology trait (VT:0000559)	bone trabecular cross-sectional area (CMO:0002311)	1	509108	43284926	Rat
2302038	Pia31	Pristane induced arthritis QTL 31	5.5	0.001	blood autoantibody amount (VT:0003725)	serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)	1	10992065	55992065	Rat
634353	Rends2	Renal damage susceptibility QTL 2		0.05	kidney blood vessel morphology trait (VT:0000530)	organ lesion measurement (CMO:0000677)	1	19333571	56983283	Rat
2313053	Bss51	Bone structure and strength QTL 51	3.8	0.0001	tibia length (VT:0004357)	tibia length (CMO:0000450)	1	1	32356093	Rat

Markers in Region

RH129445

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	29,375,806 - 29,376,021 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	31,986,649 - 31,986,863	NCBI	Rnor6.0
Rnor_5.0	1	33,411,094 - 33,411,308	UniSTS	Rnor5.0
RGSC_v3.4	1	30,183,997 - 30,184,211	UniSTS	RGSC3.4
Celera	1	28,024,767 - 28,024,981	UniSTS
Cytogenetic Map	1	p11	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001011930	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008758681	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039103353	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC083900	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000021532 ⟹ ENSRNOP00000021532

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	29,357,140 - 29,402,074 (+)	Ensembl
Rnor_6.0 Ensembl	1	31,967,982 - 32,012,919 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000081471 ⟹ ENSRNOP00000070709

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	29,357,130 - 29,376,156 (+)	Ensembl
Rnor_6.0 Ensembl	1	31,967,978 - 31,987,125 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000112286 ⟹ ENSRNOP00000076549

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	29,357,140 - 29,402,074 (+)	Ensembl

RefSeq Acc Id:

NM_001011930 ⟹ NP_001011930

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	31,185,700 - 31,230,638 (+)	NCBI
mRatBN7.2	1	29,357,140 - 29,402,078 (+)	NCBI
Rnor_6.0	1	31,967,982 - 32,012,923 (+)	NCBI
Rnor_5.0	1	33,392,425 - 33,437,368 (+)	NCBI
RGSC_v3.4	1	30,165,330 - 30,210,271 (+)	RGD
Celera	1	28,006,108 - 28,051,038 (+)	RGD

Sequence:

show sequence

CGGCCAGGGTGGATCTTCGTACAGCTGAGAAGACTGTCCCACAGGGCGCCGAGAGGCGACCGCG
ACCTCATTCTGGCTGGCCGCATTTCCTCGGCTCCCGGCTGCGGCGCCATGGACGACGCGGTGGG
CGACCTGAAGCAAGCGCTTCCGTGTGTTGCCGAGTCGCCCGCGGTCCATGTGGAGGTTTTGCAG
CGCAGCGGAAGCACTGCAAAAAAAGAAGATATAAAGCAGAGCGTTTACAGGCTGCTCAAGAGGC
ATAACATTGTGTTTGGAGATTACGTGTGGACTGAGTTTGATGAGCCTTTTCTAACTAGAAATGT
TCAGTCGGTATCTATTGTTGACACAGAATTAAAGGCTAAAGACCCTCAGCCCATTGATCTGAGT
GCATGCACCATTGCACTTCACATCTTCCAGCTGAATGAAGAAGGCCCCAGCAGTGAAAATTTGG
ATGAAGAAACAGAAAATATAATTGCAGCAAGTCACTGGGTTTTGCCTGCAGCTGAATTTCATGG
GCTTTGGGATAGCCTCGTGTATGATGTGGAGGTCAAATCACATCTCCTTGACTATGTGATGACC
ACCTTACTATTCTCAGACAAGAATGTGGACAGCAACCTTATCACCTGGAACCGGGTGGTACTGC
TGCACGGTCCTCCGGGTACTGGAAAGACATCCCTTTGTAAGGCATTAGCCCAGAAACTGACCAT
CAGACTGTCAAGCAGGTACCGGTATGGCCAGTTAATTGAAATAAACAGCCACAGCCTATTTTCT
AAGTGGTTTTCAGAAAGTGGCAAGTTGGTAACTAAGATGTTCCAGAAGATTCAGGACTTGATTG
ATGATAAAGAAGCTTTGGTGTTTGTTCTGATTGATGAGGTGGAGAGTCTTACAGCTGCTCGAAA
TGCTTGCAGGGCAGGCGCAGAGCCATCAGATGCTATCCGTGTAGTCAATGCTGTGTTGACTCAG
ATTGATCAGATTAAAAGGCATTCCAATGTGGTGATTCTGACCACTTCCAACATCACTGAGAAGA
TTGATGTGGCCTTTGTGGATAGAGCTGACATCAAACAATATATTGGCCCCCCCTCTGCAGCAGC
CATCTTCAAAATCTACCTGTCTTGTTTAGAAGAACTGATGAAGTGCCAGATCATATATCCCCGT
CAGCAGCTGTTGACCCTTCGAGAGCTGGAAATGATTGGCTTCATTGAAAATAATGTGTCGAAGT
TGAGCCTCCTTTTGAGTGAAATTTCAAGGAAGAGTGAGGGCCTCAGCGGCCGGGTCTTGAGGAA
ACTTCCTTTCCTGGCTCATGCGCTGTATATCCAGGCTCCCAGCGTCACCATCGAGGGTTTCCTC
CAGGCCCTGTCACTGGCAGTGGACAAACAGTTTGAGGAGAAAAAGAAACTCTCAGCTCATGTTT
GATCCCAGACATCCATATCTGTGGTTTTCAATGGACAGGCCCTGCCAAGGGATTGCCACTTGTG
CAAATACCCCGGGAGAAAGGGGATTCCTGTGCCAATGTCCTCCTACGTACAGAGGAATGAATGC
AACTGCTGCTAATTCCTATGGAGGGAACACCTGCTACAGAGAGCCAGAGTGCCCTGTCTCTATC
TGCCCTGCTGGATATTCTGGAAGGTTCTGTAAGTCGGATCACACTGAGTGTGCTTCCAACCCCT
ACCACAATGGGGTGCTGTGCCAGGATGGCGTCAATAACTGCACCTGCTTCTGTATGCCTGGGTA
CCAAGGCAGGTGTTGTGACTTGAAAATTGAGTTTAAGTCTTTAACCAAATCTTTCAGTGGGTAC
ACACAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_008758681 ⟹ XP_008756903

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	31,185,769 - 31,204,719 (+)	NCBI
mRatBN7.2	1	29,357,093 - 29,376,159 (+)	NCBI
Rnor_6.0	1	31,967,980 - 31,987,007 (+)	NCBI

Sequence:

show sequence

CTCGGCCAGGGTGGATCTTCGTACAGCTGAGAAGACTGTCCCACAGGGCGCCGAGAGGCGACCG
CGACCTCATTCTGGCTGGCCGCATTTCCTCGGCTCCCGGCTGCGGCGCCATGGACGACGCGGTG
GGCGACCTGAAGCAAGCGCTTCCGTGTGTTGCCGAGTCGCCCGCGGTCCATGTGGAGGTTTTGC
AGCGCAGCGGAAGCACTGCAAAAAAAGAAGATATAAAGCAGAGCGTTTACAGGCTGCTCAAGAG
GCATAACATTGTGTTTGGAGATTACGTGTGGACTGAGTTTGATGAGCCTTTTCTAACTAGAAAT
GTTCAGTCGGTATCTATTGTTGACACAGAATTAAAGGCTAAAGACCCTCAGCCCATTGATCTGA
GTGCATGCACCATTGCACTTCACATCTTCCAGCTGAATGAAGAAGGCCCCAGCAGTGAAAATTT
GGATGAAGAAACAGAAAATATAATTGCAGCAAGTCACTGGGTTTTGCCTGCAGCTGAATTTCAT
GGGCTTTGGGATAGCCTCGTGTATGATGTGGAGGTCAAATCACATCTCCTTGACTATGTGATGA
CCACCTTACTATTCTCAGACAAGAATGTGGACAGCAACCTTATCACCTGGAACCGGGTGGTACT
GCTGCACGGTCCTCCGGGTACTGGAAAGACATCCCTTTGTAAGGCATTAGCCCAGAAACTGACC
ATCAGACTGTCAAGCAGGTACCGGTATGGCCAGTTAATTGAAATAAACAGCCACAGCCTATTTT
CTAAGTGGTTTTCAGAAAGTGGCAAGTTGGTAACTAAGATGTTCCAGAAGATTCAGGACTTGAT
TGATGATAAAGAAGCTTTGGTGTTTGTTCTGATTGATGAGGTGGAGAGTCTTACAGCTGCTCGA
AATGCTTGCAGGGCAGGCGCAGAGCCATCAGATGCTATCCGTGTAGTCAATGCTGTGTTGACTC
AGATTGATCAGATTAAAAGGCATTCCAATGTGGTGATTCTGACCACTTCCAACATCACTGAGAA
GATTGATGTGGCCTTTGTGGATAGAGCTGACATCAAACAATATATTGGCCCCCCCTCTGCAGCA
GCCATCTTCAAAATCTACCTGTCTTGTTTAGAAGAACTGATGAAGTGCCAGATCATATATCCCC
GTCAGCAGCTGTTGACCCTTCGAGAGCTGGAAATGATTGGCTTCATTGAAAATAATGTGTCGAA
GTTGAGCCTCCTTTTGAGTGAAATTTCAAGGAAGAGTGAGGGCCTCAGCGGCCGGGTCTTGAGG
AAACTTCCTTTCCTGGCTCATGCGCTGTATATCCAGGCTCCCAGCGTCACCATCGAGGGTTTCC
TCCAGGCCCTGTCTCTGGCAGTGGACAAACAGTTTGAGGAGAAAAAGAAACTCTCAGCTCATGT
TTGATCCCAGACATCCATATCTGTGGTTTTCAATGGACAGGTAGGAGGTGATACCGTCTACCTC
ACAGTGTGCATCAGAAATGACTAAACCATGTAGGTCTGCAGGCCAGGCCAGACAGATGGGTGTA
CAGACTTTGTCAAAAGGACTGTTTGTGTTATTTTACAATGCACATTGAAAGGCAAACTGCCTGT
CTTTTTCACTGTTTTTAAAAGACAATTGATTCCAGTCTGTTTACATCTATGTAAAGCCCCATCC
TGACTCTAGCCTGTCAGACACAAGATGTTAAAATTTGTTTAAAATAAAGGGAGATCAAAACAGC
TTTCCTAGAGCAAGAGGAGTGCTGAATAATGCAGTTACGGCACTGAAAGATGGACTCTTGCTCC
GGCTAGAAGGGAGCGGCTACTTCCTGGCAGGAGTCTGCTTCGGTTAGCACCGGATGCTGTGGAA
TGGGTGAGAAAGACGTGCTCCTGTGATACAGAAACTGAGAAAAGGATTGCAGATAAGAAGATAA
AGACTTCTGTGATAGCGATCAGATGTTGTGTTCAGAGGAGCAGTACGTACTTTCTATGGTCAAG
AGAATCAGGCAATGTGTGTTTTGTTTTTCCAGTAATTTTACTCATATTTCAAGTGAAAATTCAT
GTTGTCAAATATAAAATAAGTCAATGTGTGTTGCACCTCACAGAATACCATGTTTTACTTCATC
TTCTGCTAAAAGTTTAGCATTAATACTTTGTACGTGAATACACTTTTAAATGGAATGCTGCCTT
TGTCATAGAATTTTTTGTAATATTAAACTTGTTTTCAGAATGCGCTTATTCCAA

hide sequence

RefSeq Acc Id:

XM_039103353 ⟹ XP_038959281

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	31,185,769 - 31,216,605 (+)	NCBI
mRatBN7.2	1	29,357,093 - 29,387,739 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001011930	(Get FASTA)	NCBI Sequence Viewer
	XP_008756903	(Get FASTA)	NCBI Sequence Viewer
	XP_038959281	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH83900	(Get FASTA)	NCBI Sequence Viewer
	EDL87668	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000021532
	ENSRNOP00000021532.3
GenBank Protein	Q5XHZ9	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001011930 ⟸ NM_001011930

- UniProtKB:

Q5XHZ9 (UniProtKB/Swiss-Prot), A6JUW1 (UniProtKB/TrEMBL), A0A8L2R3S2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MDDAVGDLKQALPCVAESPAVHVEVLQRSGSTAKKEDIKQSVYRLLKRHNIVFGDYVWTEFDEP
FLTRNVQSVSIVDTELKAKDPQPIDLSACTIALHIFQLNEEGPSSENLDEETENIIAASHWVLP
AAEFHGLWDSLVYDVEVKSHLLDYVMTTLLFSDKNVDSNLITWNRVVLLHGPPGTGKTSLCKAL
AQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKMFQKIQDLIDDKEALVFVLIDEVES
LTAARNACRAGAEPSDAIRVVNAVLTQIDQIKRHSNVVILTTSNITEKIDVAFVDRADIKQYIG
PPSAAAIFKIYLSCLEELMKCQIIYPRQQLLTLRELEMIGFIENNVSKLSLLLSEISRKSEGLS
GRVLRKLPFLAHALYIQAPSVTIEGFLQALSLAVDKQFEEKKKLSAHV

hide sequence

RefSeq Acc Id:	XP_008756903 ⟸ XM_008758681
- Peptide Label:	isoform X1
- UniProtKB:	Q5XHZ9 (UniProtKB/Swiss-Prot), A6JUW1 (UniProtKB/TrEMBL), A0A8L2R3S2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDDAVGDLKQALPCVAESPAVHVEVLQRSGSTAKKEDIKQSVYRLLKRHNIVFGDYVWTEFDEP FLTRNVQSVSIVDTELKAKDPQPIDLSACTIALHIFQLNEEGPSSENLDEETENIIAASHWVLP AAEFHGLWDSLVYDVEVKSHLLDYVMTTLLFSDKNVDSNLITWNRVVLLHGPPGTGKTSLCKAL AQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKMFQKIQDLIDDKEALVFVLIDEVES LTAARNACRAGAEPSDAIRVVNAVLTQIDQIKRHSNVVILTTSNITEKIDVAFVDRADIKQYIG PPSAAAIFKIYLSCLEELMKCQIIYPRQQLLTLRELEMIGFIENNVSKLSLLLSEISRKSEGLS GRVLRKLPFLAHALYIQAPSVTIEGFLQALSLAVDKQFEEKKKLSAHV hide sequence

Ensembl Acc Id:

ENSRNOP00000021532 ⟸ ENSRNOT00000021532

Ensembl Acc Id:

ENSRNOP00000070709 ⟸ ENSRNOT00000081471

RefSeq Acc Id:	XP_038959281 ⟸ XM_039103353
- Peptide Label:	isoform X1
- UniProtKB:	Q5XHZ9 (UniProtKB/Swiss-Prot), A6JUW1 (UniProtKB/TrEMBL), A0A8L2R3S2 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000076549 ⟸ ENSRNOT00000112286

Protein Domains

AAA+ ATPase ATPase AAA-type core

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5XHZ9-F1-model_v2	AlphaFold	Q5XHZ9	1-432	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13689571

Promoter ID:

EPDNEW_R88

Type:

initiation region

Name:

Trip13_1

Description:

thyroid hormone receptor interactor 13

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	31,967,966 - 31,968,026	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1308516	AgrOrtholog
BioCyc Gene	G2FUF-61934	BioCyc
Ensembl Genes	ENSRNOG00000015810	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000021532	ENTREZGENE
	ENSRNOT00000021532.5	UniProtKB/Swiss-Prot
Gene3D-CATH	3.40.50.300	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7133557	IMAGE-MGC_LOAD
InterPro	AAA+_ATPase	UniProtKB/Swiss-Prot
	ATPase_AAA_core	UniProtKB/Swiss-Prot
	ATPase_AAA_CS	UniProtKB/Swiss-Prot
	ClpA/B	UniProtKB/Swiss-Prot
	P-loop_NTPase	UniProtKB/Swiss-Prot
	Pch2-like	UniProtKB/Swiss-Prot
KEGG Report	rno:292206	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:95258	IMAGE-MGC_LOAD
NCBI Gene	292206	ENTREZGENE
PANTHER	PACHYTENE CHECKPOINT PROTEIN 2 HOMOLOG	UniProtKB/Swiss-Prot
	PTHR45991	UniProtKB/Swiss-Prot
Pfam	AAA	UniProtKB/Swiss-Prot
PhenoGen	Trip13	PhenoGen
PRINTS	CLPPROTEASEA	UniProtKB/Swiss-Prot
PROSITE	AAA	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000015810	RatGTEx
SMART	AAA	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF52540	UniProtKB/Swiss-Prot
UniProt	A0A8I5Y057_RAT	UniProtKB/TrEMBL
	A0A8L2R3S2	ENTREZGENE, UniProtKB/TrEMBL
	A6JUW1	ENTREZGENE, UniProtKB/TrEMBL
	PCH2_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2005-12-06	Trip13	thyroid hormone receptor interactor 13	Trip13_predicted	thyroid hormone receptor interactor 13 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Trip13_predicted	thyroid hormone receptor interactor 13 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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