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Gene: Gria3 (glutamate ionotropic receptor AMPA type subunit 3) Rattus norvegicus
Symbol: Gria3
Name: glutamate ionotropic receptor AMPA type subunit 3
Description: Exhibits AMPA glutamate receptor activity; PDZ domain binding activity; and amyloid-beta binding activity. Involved in regulation of receptor recycling; response to fungicide; and response to lithium ion. Localizes to several cellular components, including the dendrite; integral component of plasma membrane; and perikaryon. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability 94. Orthologous to human GRIA3 (glutamate ionotropic receptor AMPA type subunit 3); PARTICIPATES IN glutamate signaling pathway; long term depression; INTERACTS WITH (+)-pilocarpine; 1-nitropropane; 17beta-estradiol.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AMPA-selective glutamate receptor 3; GluA3; GluR-3; GluR-C; GluR-K3; GLUR3; glutamate receptor 3; glutamate receptor, ionotrophic, AMPA 3; glutamate receptor, ionotropic, AMPA 3; glutamate receptor, ionotropic, AMPA3 (alpha 3)
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0X127,561,843 - 127,829,763 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX127,562,660 - 127,829,753 (+)Ensembl
Rnor_5.0X127,655,758 - 127,922,244 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X3,452,523 - 3,718,486 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X3,460,084 - 3,724,042 (-)NCBI
CeleraX119,369,614 - 119,631,774 (+)NCBICelera
Cytogenetic MapXq35NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Gria3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 70958
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.