(+)-catechin multiple interactions EXP 6480464 Catechin inhibits the reaction [EDN1 protein results in decreased susceptibility to Acetylcholine] more ... CTD PMID:20977430 (+)-catechin multiple interactions ISO Edn1 (Mus musculus) 6480464 [resveratrol co-treated with Catechin co-treated with caffeic acid] results in decreased expression of EDN1 mRNA and Catechin inhibits the reaction [APOE gene mutant form results in increased expression of EDN1 protein] CTD PMID:16806235 and PMID:20093625 (-)-epigallocatechin 3-gallate multiple interactions ISO EDN1 (Homo sapiens) 6480464 epigallocatechin gallate inhibits the reaction [Hydrogen Peroxide results in increased expression of EDN1 mRNA] CTD PMID:20021702 (-)-epigallocatechin 3-gallate decreases expression ISO EDN1 (Homo sapiens) 6480464 epigallocatechin gallate results in decreased expression of EDN1 mRNA CTD PMID:20021702 (R)-noradrenaline multiple interactions EXP 6480464 1-(6-((3-methoxyestra-1 more ... CTD PMID:11435416 more ... (R)-noradrenaline increases expression EXP 6480464 Norepinephrine results in increased expression of EDN1 mRNA CTD PMID:11435416 (R)-noradrenaline increases activity EXP 6480464 Norepinephrine results in increased activity of EDN1 promoter CTD PMID:11435416 (R)-noradrenaline decreases secretion EXP 6480464 EDN1 protein results in decreased secretion of Norepinephrine CTD PMID:12184995 (R)-noradrenaline increases secretion EXP 6480464 EDN1 protein results in increased secretion of Norepinephrine CTD PMID:14759557 (S)-nicotine multiple interactions ISO Edn1 (Mus musculus) 6480464 MIR98 mRNA inhibits the reaction [Nicotine results in increased expression of EDN1 mRNA] more ... CTD PMID:33082140 (S)-nicotine increases expression ISO Edn1 (Mus musculus) 6480464 Nicotine results in increased expression of EDN1 mRNA and Nicotine results in increased expression of EDN1 protein CTD PMID:33082140 1,2-dimethylhydrazine decreases expression ISO Edn1 (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in decreased expression of EDN1 mRNA CTD PMID:22206623 1,3-dinitrobenzene increases expression EXP 6480464 3-dinitrobenzene results in increased expression of EDN1 mRNA CTD PMID:22841810 11-deoxycorticosterone multiple interactions EXP 6480464 [Sodium Chloride more ... CTD PMID:16054168 more ... 11-deoxycorticosterone increases expression EXP 6480464 Desoxycorticosterone results in increased expression of EDN1 and Desoxycorticosterone results in increased expression of EDN1 protein CTD PMID:12600921 and PMID:16054168 17alpha-ethynylestradiol affects expression ISO Edn1 (Mus musculus) 6480464 Ethinyl Estradiol affects the expression of EDN1 mRNA CTD PMID:17555576 17alpha-ethynylestradiol affects expression EXP 6480464 Ethinyl Estradiol affects the expression of EDN1 mRNA CTD PMID:20170705 and PMID:26865667 17alpha-ethynylestradiol affects expression ISO EDN1 (Homo sapiens) 6480464 Ethinyl Estradiol affects the expression of EDN1 mRNA CTD PMID:20170705 and PMID:26865667 17alpha-ethynylestradiol multiple interactions ISO Edn1 (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of EDN1 mRNA CTD PMID:17942748 17alpha-ethynylestradiol increases expression ISO Edn1 (Mus musculus) 6480464 Ethinyl Estradiol results in increased expression of EDN1 mRNA CTD PMID:17942748 17beta-estradiol multiple interactions ISO EDN1 (Homo sapiens) 6480464 [Estradiol co-treated with TGFB1 protein] results in increased expression of EDN1 mRNA more ... CTD PMID:12385860 more ... 17beta-estradiol increases secretion ISO EDN1 (Homo sapiens) 6480464 Estradiol results in increased secretion of EDN1 protein CTD PMID:21795739 17beta-estradiol increases expression ISO EDN1 (Homo sapiens) 6480464 Estradiol results in increased expression of EDN1 mRNA CTD PMID:19153601 more ... 17beta-estradiol increases expression ISO Edn1 (Mus musculus) 6480464 Estradiol results in increased expression of EDN1 mRNA CTD PMID:19484750 17beta-estradiol decreases expression ISO EDN1 (Homo sapiens) 6480464 Estradiol results in decreased expression of EDN1 mRNA and Estradiol results in decreased expression of EDN1 protein CTD PMID:12385860 more ... 1D-myo-inositol 1,4,5-trisphosphate multiple interactions EXP 6480464 cyclo(Trp-Asp-Pro-Val-Leu) inhibits the reaction [EDN1 protein results in increased chemical synthesis of Inositol 1 more ... CTD PMID:11911850 and PMID:1443220 1D-myo-inositol 1,4,5-trisphosphate increases chemical synthesis ISO EDN1 (Homo sapiens) 6480464 EDN1 protein results in increased chemical synthesis of Inositol 1 more ... CTD PMID:20691780 1D-myo-inositol 1,4,5-trisphosphate multiple interactions ISO EDN1 (Homo sapiens) 6480464 CAT protein inhibits the reaction [Glucose promotes the reaction [EDN1 protein results in increased chemical synthesis of Inositol 1 more ... CTD PMID:20691780 1D-myo-inositol 1,4,5-trisphosphate increases chemical synthesis EXP 6480464 EDN1 protein results in increased chemical synthesis of Inositol 1 more ... CTD PMID:11911850 1D-myo-inositol 1,4,5-trisphosphate increases abundance EXP 6480464 EDN1 protein results in increased abundance of Inositol 1 more ... CTD PMID:1443220 2,2',5,5'-tetrachlorobiphenyl decreases expression ISO EDN1 (Homo sapiens) 6480464 2 more ... CTD PMID:36804509 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of EDN1 mRNA CTD PMID:22298810 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of EDN1 mRNA CTD PMID:33387578 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Edn1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of EDN1 mRNA CTD PMID:16120747 more ... 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Edn1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of EDN1 mRNA CTD PMID:17942748 and PMID:19933214 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Edn1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of EDN1 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Edn1 (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of EDN1 mRNA CTD PMID:17942748 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of EDN1 mRNA CTD PMID:21724226 2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile multiple interactions ISO EDN1 (Homo sapiens) 6480464 Verapamil inhibits the reaction [EDN1 protein results in increased expression of NPPB mRNA] and Verapamil inhibits the reaction [EDN1 protein results in increased expression of NPPB protein] CTD PMID:28942281 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine multiple interactions EXP 6480464 Carbon Tetrachloride promotes the reaction [EDN1 protein results in increased abundance of Platelet Activating Factor] more ... CTD PMID:18205269 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine increases abundance EXP 6480464 EDN1 protein results in increased abundance of Platelet Activating Factor CTD PMID:18205269 2-butoxyethanol increases expression ISO Edn1 (Mus musculus) 6480464 n-butoxyethanol results in increased expression of EDN1 mRNA CTD PMID:19812364 2-tert-butylhydroquinone increases expression ISO EDN1 (Homo sapiens) 6480464 2-tert-butylhydroquinone results in increased expression of EDN1 mRNA CTD PMID:35724838 3',5'-cyclic GMP multiple interactions EXP 6480464 Puromycin Aminonucleoside inhibits the reaction [EDN1 protein results in increased abundance of Cyclic GMP] CTD PMID:12972712 3',5'-cyclic GMP increases abundance EXP 6480464 EDN1 protein results in increased abundance of Cyclic GMP CTD PMID:12972712 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine multiple interactions EXP 6480464 Enalapril inhibits the reaction [Puromycin Aminonucleoside results in increased expression of EDN1 mRNA] more ... CTD PMID:12972712 more ... 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine increases expression EXP 6480464 Puromycin Aminonucleoside results in increased expression of EDN1 mRNA CTD PMID:12972712 more ... 3,3',4,4',5-pentachlorobiphenyl decreases expression EXP 6480464 3 more ... CTD PMID:23196670 3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione multiple interactions EXP 6480464 bisindolylmaleimide I inhibits the reaction [[EDN1 protein binds to and results in increased activity of EDNRB protein] which results in increased activity of NOS1 protein] more ... CTD PMID:12169099 and PMID:15245872 3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione decreases expression EXP 6480464 bisindolylmaleimide I results in decreased expression of EDN1 mRNA and bisindolylmaleimide I results in decreased expression of EDN1 protein CTD PMID:16080914 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO Edn1 (Mus musculus) 6480464 [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of EDN1 mRNA CTD PMID:16054899 3H-1,2-dithiole-3-thione increases expression EXP 6480464 1 and 2-dithiol-3-thione results in increased expression of EDN1 mRNA CTD PMID:19162173 4,4'-diaminodiphenylmethane increases expression EXP 6480464 4 and 4'-diaminodiphenylmethane results in increased expression of EDN1 protein CTD PMID:26116029 4,4'-sulfonyldiphenol affects expression ISO Edn1 (Mus musculus) 6480464 bisphenol S affects the expression of EDN1 mRNA CTD PMID:30951980 4-hydroxy-TEMPO decreases expression EXP 6480464 tempol results in decreased expression of EDN1 mRNA and tempol results in decreased expression of EDN1 protein CTD PMID:28039404 4-hydroxy-TEMPO multiple interactions ISO Edn1 (Mus musculus) 6480464 tempol inhibits the reaction [AGT protein results in increased expression of EDN1 mRNA] CTD PMID:17391658 4-hydroxynon-2-enal decreases expression ISO Edn1 (Mus musculus) 6480464 4-hydroxy-2-nonenal results in decreased expression of EDN1 mRNA CTD PMID:19191707 4-hydroxyphenyl retinamide increases expression ISO Edn1 (Mus musculus) 6480464 Fenretinide results in increased expression of EDN1 mRNA CTD PMID:28973697 5-fluorouracil increases expression ISO EDN1 (Homo sapiens) 6480464 Fluorouracil results in increased expression of EDN1 mRNA and Fluorouracil results in increased expression of EDN1 protein CTD PMID:1606078 and PMID:19098008 5-formyltetrahydrofolic acid increases expression ISO Edn1 (Mus musculus) 6480464 Leucovorin results in increased expression of EDN1 mRNA and Leucovorin results in increased expression of EDN1 protein CTD PMID:16925845 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of EDN1 mRNA CTD PMID:25825206 6alpha-methylprednisolone multiple interactions EXP 6480464 Methylprednisolone inhibits the reaction [Puromycin Aminonucleoside results in increased expression of EDN1 mRNA] CTD PMID:7756592 7,9-dihydro-1H-purine-2,6,8(3H)-trione multiple interactions ISO EDN1 (Homo sapiens) 6480464 resveratrol inhibits the reaction [Uric Acid results in increased expression of EDN1 mRNA] and resveratrol inhibits the reaction [Uric Acid results in increased expression of EDN1 protein] CTD PMID:25493383 7,9-dihydro-1H-purine-2,6,8(3H)-trione increases expression ISO EDN1 (Homo sapiens) 6480464 Uric Acid results in increased expression of EDN1 mRNA and Uric Acid results in increased expression of EDN1 protein CTD PMID:25493383 7-NITROINDAZOLE multiple interactions EXP 6480464 7-nitroindazole inhibits the reaction [[EDN1 protein binds to and results in increased activity of EDNRB protein] which results in increased activity of NOS1 protein] CTD PMID:15245872 8-bromo-3',5'-cyclic GMP multiple interactions EXP 6480464 8-bromocyclic GMP inhibits the reaction [[EDN1 protein binds to and results in increased activity of EDNRB protein] which results in decreased activity of TH protein] CTD PMID:16023617 8-bromo-3',5'-cyclic GMP multiple interactions ISO EDN1 (Homo sapiens) 6480464 8-bromocyclic GMP inhibits the reaction [cobaltous chloride results in increased expression of EDN1 mRNA] and 8-bromocyclic GMP inhibits the reaction [cobaltous chloride results in increased expression of EDN1 protein] CTD PMID:29165873 acetamide increases expression EXP 6480464 acetamide results in increased expression of EDN1 mRNA CTD PMID:31881176 acetylcholine decreases response to substance EXP 6480464 EDN1 protein results in decreased susceptibility to Acetylcholine CTD PMID:20977430 acetylcholine multiple interactions EXP 6480464 acetovanillone inhibits the reaction [EDN1 protein results in decreased susceptibility to Acetylcholine] more ... CTD PMID:20977430 acrolein multiple interactions ISO EDN1 (Homo sapiens) 6480464 cesium chloride inhibits the reaction [Acrolein results in increased expression of EDN1 protein] and Rotenone inhibits the reaction [Acrolein results in increased expression of EDN1 protein] CTD PMID:22928487 acrolein increases expression ISO EDN1 (Homo sapiens) 6480464 Acrolein results in increased expression of EDN1 protein CTD PMID:22928487 actinomycin D multiple interactions ISO EDN1 (Homo sapiens) 6480464 Dactinomycin inhibits the reaction [EDN1 protein results in increased expression of ADRB2 mRNA] CTD PMID:22483689 afimoxifene increases expression ISO EDN1 (Homo sapiens) 6480464 afimoxifene results in increased expression of EDN1 mRNA CTD PMID:19153601 afimoxifene multiple interactions ISO EDN1 (Homo sapiens) 6480464 GPER1 protein affects the reaction [afimoxifene results in increased expression of EDN1 mRNA] CTD PMID:19153601 aflatoxin B1 affects expression ISO EDN1 (Homo sapiens) 6480464 Aflatoxin B1 affects the expression of EDN1 protein CTD PMID:20106945 aflatoxin B1 increases expression ISO EDN1 (Homo sapiens) 6480464 Aflatoxin B1 results in increased expression of EDN1 mRNA CTD PMID:21632981 more ... aflatoxin B1 decreases methylation ISO EDN1 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of EDN1 gene CTD PMID:27153756 agmatine multiple interactions ISO EDN1 (Homo sapiens) 6480464 Agmatine inhibits the reaction [Palmitic Acid results in decreased expression of EDN1 protein] CTD PMID:35747990 aldehydo-D-glucose multiple interactions ISO EDN1 (Homo sapiens) 6480464 carvedilol inhibits the reaction [Glucose results in increased expression of EDN1 mRNA] more ... CTD PMID:16428915 more ... aldehydo-D-glucose decreases expression ISO EDN1 (Homo sapiens) 6480464 Glucose results in decreased expression of EDN1 mRNA CTD PMID:31655124 aldehydo-D-glucose increases expression EXP 6480464 Glucose results in increased expression of EDN1 protein CTD PMID:26891083 aldehydo-D-glucose increases expression ISO EDN1 (Homo sapiens) 6480464 Glucose results in increased expression of EDN1 mRNA and Glucose results in increased expression of EDN1 protein CTD PMID:16428915 more ... aldehydo-D-glucose multiple interactions EXP 6480464 Glucose affects the reaction [EDN1 protein affects the abundance of and affects the localization of Calcium] more ... CTD PMID:12821678 and PMID:26891083 aldosterone increases expression EXP 6480464 Aldosterone results in increased expression of EDN1 protein CTD PMID:18660453 aldosterone multiple interactions EXP 6480464 [EDN1 protein binds to and results in increased activity of EDNRA protein] promotes the reaction [Aldosterone results in increased expression of IL18 mRNA] CTD PMID:18660453 all-trans-retinoic acid multiple interactions ISO EDN1 (Homo sapiens) 6480464 [Tretinoin co-treated with Ascorbic Acid] results in increased expression of EDN1 mRNA CTD PMID:16443354 all-trans-retinoic acid decreases expression ISO Edn1 (Mus musculus) 6480464 Tretinoin results in decreased expression of EDN1 protein CTD PMID:17551590 all-trans-retinoic acid increases expression ISO EDN1 (Homo sapiens) 6480464 Tretinoin results in increased expression of EDN1 mRNA CTD PMID:15498508 all-trans-retinoic acid decreases expression EXP 6480464 Tretinoin results in decreased expression of EDN1 protein CTD PMID:16619265 alpha-Zearalanol multiple interactions ISO EDN1 (Homo sapiens) 6480464 Zeranol inhibits the reaction [Homocysteine affects the expression of EDN1 protein] CTD PMID:16757814 aminoguanidine multiple interactions EXP 6480464 pimagedine inhibits the reaction [Mercuric Chloride results in increased expression of EDN1 mRNA] CTD PMID:9853001 amlodipine affects expression ISO EDN1 (Homo sapiens) 6480464 Amlodipine affects the expression of EDN1 protein CTD PMID:11369837 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of EDN1 mRNA CTD PMID:16483693 ampicillin increases expression ISO EDN1 (Homo sapiens) 6480464 Ampicillin results in increased expression of EDN1 mRNA CTD PMID:21632981 andrographolide multiple interactions ISO EDN1 (Homo sapiens) 6480464 andrographolide inhibits the reaction [cobaltous chloride results in increased expression of EDN1 mRNA] more ... CTD PMID:27297870 and PMID:29165873 andrographolide increases expression ISO EDN1 (Homo sapiens) 6480464 andrographolide results in increased expression of EDN1 mRNA CTD PMID:35724838 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO EDN1 (Homo sapiens) 6480464 pyrazolanthrone inhibits the reaction [Glucose results in increased expression of EDN1 mRNA] CTD PMID:24376792 apocynin multiple interactions EXP 6480464 [polyethylene glycol-superoxide dismutase co-treated with acetovanillone] inhibits the reaction [EDN1 protein results in increased expression of and results in increased cleavage of PARP1 protein] more ... CTD PMID:20977430 more ... apocynin multiple interactions ISO Edn1 (Mus musculus) 6480464 acetovanillone inhibits the reaction [AGT protein results in increased expression of EDN1 mRNA] CTD PMID:17391658 arsenite(3-) affects expression ISO Edn1 (Mus musculus) 6480464 arsenite affects the expression of EDN1 mRNA CTD PMID:15738583 arsenous acid increases expression ISO EDN1 (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of EDN1 mRNA CTD PMID:26705709 asbestos decreases expression ISO EDN1 (Homo sapiens) 6480464 Asbestos results in decreased expression of EDN1 mRNA CTD PMID:22398240 atenolol affects response to substance ISO EDN1 (Homo sapiens) 6480464 EDN1 gene polymorphism affects the susceptibility to Atenolol CTD PMID:15188945 atorvastatin calcium decreases expression ISO EDN1 (Homo sapiens) 6480464 Atorvastatin results in decreased expression of EDN1 protein CTD PMID:16360360 atrasentan multiple interactions EXP 6480464 atrasentan inhibits the reaction [EDN1 protein results in increased abundance of Reactive Oxygen Species] CTD PMID:22431579 atropine multiple interactions ISO EDN1 (Homo sapiens) 6480464 EDN1 protein results in decreased activity of [Atropine co-treated with Histamine] CTD PMID:12906840 Bardoxolone methyl increases expression ISO EDN1 (Homo sapiens) 6480464 bardoxolone methyl results in increased expression of EDN1 mRNA CTD PMID:35724838 belinostat increases expression ISO EDN1 (Homo sapiens) 6480464 belinostat results in increased expression of EDN1 mRNA CTD PMID:26272509 belinostat multiple interactions ISO EDN1 (Homo sapiens) 6480464 [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EDN1 mRNA CTD PMID:27188386 benazepril decreases expression EXP 6480464 benazepril results in decreased expression of EDN1 mRNA and benazepril results in decreased expression of EDN1 protein CTD PMID:16191423 benazepril multiple interactions EXP 6480464 [Valsartan co-treated with benazepril] results in decreased expression of EDN1 protein CTD PMID:11136700 benazepril increases activity EXP 6480464 benazepril results in increased activity of EDN1 protein CTD PMID:7528292 benzo[a]pyrene decreases expression ISO EDN1 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of EDN1 mRNA CTD PMID:20106945 and PMID:31255691 benzo[a]pyrene increases expression ISO EDN1 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased expression of EDN1 mRNA CTD PMID:16269432 more ... benzo[a]pyrene decreases expression ISO Edn1 (Mus musculus) 6480464 Benzo(a)pyrene results in decreased expression of EDN1 mRNA CTD PMID:21569818 benzo[a]pyrene multiple interactions ISO Edn1 (Mus musculus) 6480464 Benzo(a)pyrene promotes the reaction [AHR protein binds to EDN1 promoter] CTD PMID:19654925 benzo[a]pyrene affects expression ISO EDN1 (Homo sapiens) 6480464 Benzo(a)pyrene affects the expression of EDN1 mRNA CTD PMID:21632981 benzo[a]pyrene diol epoxide I increases expression ISO EDN1 (Homo sapiens) 6480464 7 more ... CTD PMID:20382639 and PMID:26238291 beta-carotene multiple interactions ISO Edn1 (Mus musculus) 6480464 [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of EDN1 mRNA CTD PMID:24657404 bezafibrate decreases expression ISO EDN1 (Homo sapiens) 6480464 Bezafibrate results in decreased expression of EDN1 protein CTD PMID:11330878 bezafibrate multiple interactions EXP 6480464 Bezafibrate inhibits the reaction [Streptozocin results in increased expression of EDN1 mRNA] CTD PMID:12967931 bilirubin IXalpha multiple interactions ISO EDN1 (Homo sapiens) 6480464 Bilirubin inhibits the reaction [cobaltous chloride results in increased expression of EDN1 mRNA] and Bilirubin inhibits the reaction [cobaltous chloride results in increased secretion of EDN1 protein] CTD PMID:27297870 bis(2-chloroethyl) sulfide increases expression ISO EDN1 (Homo sapiens) 6480464 Mustard Gas results in increased expression of EDN1 mRNA CTD PMID:25102026 bis(2-ethylhexyl) phthalate affects expression EXP 6480464 Diethylhexyl Phthalate affects the expression of EDN1 mRNA CTD PMID:20920545 bis(2-ethylhexyl) phthalate multiple interactions EXP 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of EDN1 mRNA CTD PMID:31199487 bisphenol A affects expression ISO EDN1 (Homo sapiens) 6480464 bisphenol A affects the expression of EDN1 mRNA CTD PMID:20170705 bisphenol A increases expression ISO EDN1 (Homo sapiens) 6480464 bisphenol A analog results in increased expression of EDN1 mRNA CTD PMID:32387340 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of EDN1 mRNA CTD PMID:30816183 more ... bisphenol A decreases expression ISO Edn1 (Mus musculus) 6480464 bisphenol A results in decreased expression of EDN1 mRNA CTD PMID:30951980 bisphenol A decreases expression ISO EDN1 (Homo sapiens) 6480464 bisphenol A results in decreased expression of EDN1 mRNA CTD PMID:29275510 and PMID:29718440 bisphenol A decreases secretion ISO EDN1 (Homo sapiens) 6480464 bisphenol A results in decreased secretion of EDN1 protein CTD PMID:27745655 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of EDN1 mRNA CTD PMID:25181051 bisphenol F affects expression ISO Edn1 (Mus musculus) 6480464 bisphenol F affects the expression of EDN1 mRNA CTD PMID:30951980 bleomycin A2 increases expression EXP 6480464 Bleomycin results in increased expression of EDN1 mRNA CTD PMID:26093215 bleomycin A2 multiple interactions EXP 6480464 Phytochemicals inhibits the reaction [Bleomycin results in increased expression of EDN1 mRNA] CTD PMID:26093215 bosentan decreases activity EXP 6480464 bosentan results in decreased activity of EDN1 protein CTD PMID:10961375 bosentan decreases activity ISO EDN1 (Homo sapiens) 6480464 bosentan results in decreased activity of EDN1 protein CTD PMID:22796455 bosentan decreases expression EXP 6480464 bosentan results in decreased expression of EDN1 protein CTD PMID:16431896 bosentan multiple interactions ISO EDN1 (Homo sapiens) 6480464 bosentan inhibits the reaction [EDN1 protein results in increased expression of ADRB2 mRNA] more ... CTD PMID:20392896 more ... bosentan multiple interactions EXP 6480464 3 more ... CTD PMID:10474778 more ... BQ 123 multiple interactions ISO Edn1 (Mus musculus) 6480464 cyclo(Trp-Asp-Pro-Val-Leu) inhibits the reaction [[APOE protein affects the susceptibility to Vehicle Emissions] which results in increased expression of EDN1 mRNA] more ... CTD PMID:12839867 more ... BQ 123 multiple interactions EXP 6480464 3 more ... CTD PMID:11093786 more ... BQ 123 decreases activity ISO EDN1 (Homo sapiens) 6480464 cyclo(Trp-Asp-Pro-Val-Leu) results in decreased activity of EDN1 protein CTD PMID:12906840 BQ 123 increases secretion ISO EDN1 (Homo sapiens) 6480464 cyclo(Trp-Asp-Pro-Val-Leu) results in increased secretion of EDN1 protein CTD PMID:24557580 BQ 123 multiple interactions ISO EDN1 (Homo sapiens) 6480464 [BQ 788 co-treated with cyclo(Trp-Asp-Pro-Val-Leu)] inhibits the reaction [EDN1 protein results in increased phosphorylation of PTK2 protein] more ... CTD PMID:12875994 more ... BQ 485 multiple interactions EXP 6480464 BQ 485 inhibits the reaction [EDN1 protein results in increased abundance of Reactive Oxygen Species] CTD PMID:16391241 buta-1,3-diene decreases expression ISO Edn1 (Mus musculus) 6480464 1 and 3-butadiene results in decreased expression of EDN1 mRNA CTD PMID:29038090 Butylbenzyl phthalate multiple interactions EXP 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of EDN1 mRNA CTD PMID:31199487 cadmium atom increases expression ISO EDN1 (Homo sapiens) 6480464 Cadmium results in increased expression of EDN1 mRNA CTD PMID:21120746 cadmium atom multiple interactions EXP 6480464 Cadmium promotes the reaction [EDN1 protein results in increased metabolism of Phosphatidylinositols] CTD PMID:9439784 cadmium atom decreases activity EXP 6480464 Cadmium results in decreased activity of EDN1 protein CTD PMID:8553374 cadmium dichloride increases expression ISO EDN1 (Homo sapiens) 6480464 Cadmium Chloride results in increased expression of EDN1 mRNA CTD PMID:18560533 cadmium dichloride multiple interactions ISO EDN1 (Homo sapiens) 6480464 TNF affects the reaction [Cadmium Chloride results in increased expression of EDN1 mRNA] CTD PMID:18560533 caesium chloride multiple interactions ISO EDN1 (Homo sapiens) 6480464 cesium chloride inhibits the reaction [Acrolein results in increased expression of EDN1 protein] CTD PMID:22928487 caffeine increases activity EXP 6480464 Caffeine results in increased activity of EDN1 protein CTD PMID:1860718 Calcimycin multiple interactions EXP 6480464 [EDN1 protein co-treated with Calcimycin] results in increased abundance of Superoxides more ... CTD PMID:20977430 calcitriol decreases expression ISO EDN1 (Homo sapiens) 6480464 Calcitriol results in decreased expression of EDN1 mRNA CTD PMID:16002434 calcitriol multiple interactions ISO EDN1 (Homo sapiens) 6480464 [Testosterone co-treated with Calcitriol] results in increased expression of EDN1 mRNA CTD PMID:21592394 calcitriol increases expression ISO EDN1 (Homo sapiens) 6480464 Calcitriol results in increased expression of EDN1 mRNA CTD PMID:21592394 calcium atom multiple interactions ISO EDN1 (Homo sapiens) 6480464 EDN1 protein results in increased transport of and results in increased abundance of Calcium and Propofol inhibits the reaction [EDN1 protein affects the transport of Calcium] CTD PMID:27226631 and PMID:9138053 calcium atom multiple interactions ISO Edn1 (Mus musculus) 6480464 EDN1 protein affects the localization of and affects the abundance of Calcium CTD PMID:11425647 calcium atom increases uptake ISO Edn1 (Mus musculus) 6480464 EDN1 protein results in increased uptake of Calcium CTD PMID:11425647 calcium atom affects localization EXP 6480464 EDN1 protein affects the localization of Calcium CTD PMID:12628492 calcium atom increases abundance EXP 6480464 EDN1 protein results in increased abundance of Calcium CTD PMID:1443220 calcium atom multiple interactions EXP 6480464 Carvedilol inhibits the reaction [EDN1 protein results in increased import of and results in increased abundance of Calcium] more ... CTD PMID:12821678 more ... calcium atom affects transport ISO EDN1 (Homo sapiens) 6480464 EDN1 protein affects the transport of Calcium CTD PMID:9138053 calcium(0) multiple interactions ISO EDN1 (Homo sapiens) 6480464 EDN1 protein results in increased transport of and results in increased abundance of Calcium and Propofol inhibits the reaction [EDN1 protein affects the transport of Calcium] CTD PMID:27226631 and PMID:9138053 calcium(0) multiple interactions ISO Edn1 (Mus musculus) 6480464 EDN1 protein affects the localization of and affects the abundance of Calcium CTD PMID:11425647 calcium(0) increases uptake ISO Edn1 (Mus musculus) 6480464 EDN1 protein results in increased uptake of Calcium CTD PMID:11425647 calcium(0) affects localization EXP 6480464 EDN1 protein affects the localization of Calcium CTD PMID:12628492 calcium(0) increases abundance EXP 6480464 EDN1 protein results in increased abundance of Calcium CTD PMID:1443220 calcium(0) multiple interactions EXP 6480464 Carvedilol inhibits the reaction [EDN1 protein results in increased import of and results in increased abundance of Calcium] more ... CTD PMID:12821678 more ... calcium(0) affects transport ISO EDN1 (Homo sapiens) 6480464 EDN1 protein affects the transport of Calcium CTD PMID:9138053 Calphostin C decreases activity EXP 6480464 calphostin C results in decreased activity of EDN1 protein CTD PMID:15464066 Candesartan cilexetil multiple interactions EXP 6480464 candesartan cilexetil inhibits the reaction [Mercuric Chloride results in increased expression of EDN1 mRNA] CTD PMID:9853001 capsaicin decreases activity ISO EDN1 (Homo sapiens) 6480464 EDN1 protein results in decreased activity of Capsaicin CTD PMID:9932722 capsaicin multiple interactions ISO EDN1 (Homo sapiens) 6480464 EDN1 protein promotes the reaction [Capsaicin results in increased activity of TRPV1 protein] and FR 139317 inhibits the reaction [EDN1 protein results in decreased activity of Capsaicin] CTD PMID:19429182 and PMID:9932722 carbon atom decreases activity EXP 6480464 Carbon analog results in decreased activity of EDN1 protein CTD PMID:20214918 carbon monoxide increases expression EXP 6480464 Carbon Monoxide results in increased expression of EDN1 mRNA and Carbon Monoxide results in increased expression of EDN1 protein CTD PMID:11781074 carbon monoxide increases expression ISO Edn1 (Mus musculus) 6480464 Carbon Monoxide results in increased expression of EDN1 mRNA CTD PMID:20197249 carbon monoxide multiple interactions EXP 6480464 Carbon Monoxide deficiency promotes the reaction [HMOX2 mutant form results in increased expression of EDN1 protein] CTD PMID:12969895 carbon nanotube decreases expression ISO EDN1 (Homo sapiens) 6480464 Nanotubes and Carbon analog results in decreased expression of EDN1 mRNA CTD PMID:25102311 carbon nanotube increases expression ISO Edn1 (Mus musculus) 6480464 Nanotubes and Carbon analog results in increased expression of EDN1 mRNA CTD PMID:25554681 carbon nanotube affects expression ISO Edn1 (Mus musculus) 6480464 Nanotubes and Carbon affects the expression of EDN1 mRNA CTD PMID:25554681 carvedilol decreases secretion ISO EDN1 (Homo sapiens) 6480464 carvedilol results in decreased secretion of EDN1 protein CTD PMID:11078433 carvedilol decreases expression EXP 6480464 carvedilol results in decreased expression of EDN1 mRNA CTD PMID:18971572 carvedilol multiple interactions EXP 6480464 carvedilol inhibits the reaction [EDN1 protein results in increased import of and results in increased abundance of Calcium] CTD PMID:14711191 carvedilol decreases expression ISO EDN1 (Homo sapiens) 6480464 carvedilol results in decreased expression of EDN1 mRNA and carvedilol results in decreased expression of EDN1 protein CTD PMID:9500873 carvedilol multiple interactions ISO EDN1 (Homo sapiens) 6480464 carvedilol inhibits the reaction [Glucose results in increased expression of EDN1 mRNA] and carvedilol inhibits the reaction [Glucose results in increased expression of EDN1 protein] CTD PMID:16428915 chelerythrine multiple interactions EXP 6480464 chelerythrine inhibits the reaction [EDN1 protein results in increased expression of NCF1 protein] CTD PMID:18436224 chenodeoxycholic acid decreases expression EXP 6480464 Chenodeoxycholic Acid results in decreased expression of EDN1 mRNA CTD PMID:16357303 chetomin multiple interactions ISO EDN1 (Homo sapiens) 6480464 chetomin inhibits the reaction [Oxygen deficiency results in increased expression of EDN1 mRNA] and chetomin inhibits the reaction [Oxygen deficiency results in increased expression of EDN1 protein] CTD PMID:21926265 chlordecone increases expression ISO Edn1 (Mus musculus) 6480464 Chlordecone results in increased expression of EDN1 mRNA CTD PMID:33711761 chlorpyrifos increases expression ISO Edn1 (Mus musculus) 6480464 Chlorpyrifos results in increased expression of EDN1 mRNA CTD PMID:37019170 choline increases expression ISO Edn1 (Mus musculus) 6480464 Choline results in increased expression of EDN1 protein CTD PMID:27567547 choline multiple interactions ISO Edn1 (Mus musculus) 6480464 Ursolic Acid inhibits the reaction [Choline results in increased expression of EDN1 protein] CTD PMID:27567547 chromium(6+) affects expression ISO Edn1 (Mus musculus) 6480464 chromium hexavalent ion affects the expression of EDN1 mRNA CTD PMID:28472532 chrysin increases expression ISO EDN1 (Homo sapiens) 6480464 chrysin results in increased expression of EDN1 mRNA CTD PMID:18457675 cicaprost decreases expression ISO EDN1 (Homo sapiens) 6480464 cicaprost results in decreased expression of EDN1 protein CTD PMID:12391278 cis-caffeic acid multiple interactions ISO Edn1 (Mus musculus) 6480464 [resveratrol co-treated with Catechin co-treated with caffeic acid] results in decreased expression of EDN1 mRNA CTD PMID:16806235 cisplatin increases expression ISO EDN1 (Homo sapiens) 6480464 Cisplatin results in increased expression of EDN1 mRNA CTD PMID:21674241 cisplatin multiple interactions EXP 6480464 montelukast inhibits the reaction [Cisplatin results in increased secretion of EDN1 protein] CTD PMID:28902463 cisplatin increases secretion EXP 6480464 Cisplatin results in increased secretion of EDN1 protein CTD PMID:28902463 cisplatin decreases response to substance ISO EDN1 (Homo sapiens) 6480464 EDN1 results in decreased susceptibility to Cisplatin CTD PMID:21656314 cisplatin decreases expression EXP 6480464 Cisplatin results in decreased expression of EDN1 mRNA CTD PMID:22023808 cisplatin multiple interactions ISO EDN1 (Homo sapiens) 6480464 cyclo(Trp-Asp-Pro-Val-Leu) inhibits the reaction [EDN1 results in decreased susceptibility to Cisplatin] CTD PMID:21656314 clofibrate multiple interactions EXP 6480464 Clofibrate inhibits the reaction [Desoxycorticosterone results in increased expression of EDN1 protein] CTD PMID:16054168 cobalt dichloride decreases expression EXP 6480464 cobaltous chloride results in decreased expression of EDN1 mRNA CTD PMID:15948191 cobalt dichloride increases secretion ISO EDN1 (Homo sapiens) 6480464 cobaltous chloride results in increased secretion of EDN1 protein CTD PMID:27297870 cobalt dichloride increases expression ISO EDN1 (Homo sapiens) 6480464 cobaltous chloride results in increased expression of EDN1 mRNA and cobaltous chloride results in increased expression of EDN1 protein CTD PMID:10939628 more ... cobalt dichloride increases expression EXP 6480464 cobaltous chloride results in increased expression of EDN1 mRNA and cobaltous chloride results in increased expression of EDN1 protein CTD PMID:11078357 more ... cobalt dichloride multiple interactions ISO EDN1 (Homo sapiens) 6480464 8-bromocyclic GMP inhibits the reaction [cobaltous chloride results in increased expression of EDN1 mRNA] more ... CTD PMID:10939628 more ... cobalt dichloride decreases expression ISO EDN1 (Homo sapiens) 6480464 cobaltous chloride results in decreased expression of EDN1 mRNA CTD PMID:19320972 cocaine increases expression EXP 6480464 Cocaine results in increased expression of EDN1 protein CTD PMID:17420087 cocaine increases expression ISO EDN1 (Homo sapiens) 6480464 Cocaine results in increased expression of EDN1 protein CTD PMID:11948058 more ... coenzyme Q10 multiple interactions ISO EDN1 (Homo sapiens) 6480464 coenzyme Q10 inhibits the reaction [Lamivudine results in increased secretion of EDN1 protein] more ... CTD PMID:23640862 colforsin daropate hydrochloride multiple interactions ISO EDN1 (Homo sapiens) 6480464 Colforsin inhibits the reaction [EDN1 protein results in increased expression of CALCRL mRNA] and Colforsin inhibits the reaction [EDN1 protein results in increased expression of ICAM2 mRNA] CTD PMID:25194819 copper atom multiple interactions EXP 6480464 Copper promotes the reaction [[Iron co-treated with Diethylnitrosamine] results in increased expression of EDN1 protein] CTD PMID:20302851 copper(0) multiple interactions EXP 6480464 Copper promotes the reaction [[Iron co-treated with Diethylnitrosamine] results in increased expression of EDN1 protein] CTD PMID:20302851 copper(II) sulfate increases expression ISO EDN1 (Homo sapiens) 6480464 Copper Sulfate results in increased expression of EDN1 mRNA CTD PMID:19549813 corticosterone increases secretion EXP 6480464 EDN1 results in increased secretion of Corticosterone CTD PMID:1659878 coumestrol decreases expression ISO EDN1 (Homo sapiens) 6480464 Coumestrol results in decreased expression of EDN1 mRNA CTD PMID:19167446 coumestrol multiple interactions ISO EDN1 (Homo sapiens) 6480464 [Coumestrol co-treated with resveratrol] results in decreased expression of EDN1 mRNA CTD PMID:19167446 crocidolite asbestos increases expression ISO EDN1 (Homo sapiens) 6480464 Asbestos and Crocidolite results in increased expression of EDN1 mRNA CTD PMID:25351596 crocidolite asbestos decreases expression ISO EDN1 (Homo sapiens) 6480464 Asbestos and Crocidolite results in decreased expression of EDN1 mRNA CTD PMID:29523930 cycloheximide multiple interactions ISO EDN1 (Homo sapiens) 6480464 [Cycloheximide co-treated with EDN1 protein] results in increased expression of ADRB2 mRNA CTD PMID:22483689 cyclophosphamide increases expression ISO EDN1 (Homo sapiens) 6480464 Cyclophosphamide results in increased expression of EDN1 protein CTD PMID:17562616 and PMID:18548196 cyclosporin A multiple interactions EXP 6480464 Cyclosporine inhibits the reaction [Isoproterenol results in increased activity of EDN1 promoter] CTD PMID:11435416 cyclosporin A decreases expression ISO EDN1 (Homo sapiens) 6480464 Cyclosporine results in decreased expression of EDN1 mRNA CTD PMID:27989131 cylindrospermopsin increases expression ISO EDN1 (Homo sapiens) 6480464 cylindrospermopsin results in increased expression of EDN1 mRNA CTD PMID:24921660 cytarabine multiple interactions ISO EDN1 (Homo sapiens) 6480464 EDN1 mutant form inhibits the reaction [VEGFC protein results in decreased susceptibility to Cytarabine] CTD PMID:24184161 cytarabine multiple interactions ISO Edn1 (Mus musculus) 6480464 EDN1 mutant form affects the reaction [VEGFC protein results in decreased susceptibility to Cytarabine] CTD PMID:24184161 D-glucose multiple interactions ISO EDN1 (Homo sapiens) 6480464 carvedilol inhibits the reaction [Glucose results in increased expression of EDN1 mRNA] more ... CTD PMID:16428915 more ... D-glucose increases expression EXP 6480464 Glucose results in increased expression of EDN1 protein CTD PMID:26891083 D-glucose decreases expression ISO EDN1 (Homo sapiens) 6480464 Glucose results in decreased expression of EDN1 mRNA CTD PMID:31655124 D-glucose increases expression ISO EDN1 (Homo sapiens) 6480464 Glucose results in increased expression of EDN1 mRNA and Glucose results in increased expression of EDN1 protein CTD PMID:16428915 more ... D-glucose multiple interactions EXP 6480464 Glucose affects the reaction [EDN1 protein affects the abundance of and affects the localization of Calcium] more ... CTD PMID:12821678 and PMID:26891083 dantrolene decreases activity EXP 6480464 Dantrolene results in decreased activity of EDN1 protein CTD PMID:12628492 dapsone multiple interactions ISO Edn1 (Mus musculus) 6480464 Dapsone inhibits the reaction [Paraquat results in increased expression of EDN1 mRNA] CTD PMID:21765237 daunorubicin increases expression EXP 6480464 Daunorubicin results in increased expression of EDN1 protein CTD PMID:20888384 daunorubicin multiple interactions EXP 6480464 telmisartan inhibits the reaction [Daunorubicin results in increased expression of EDN1 protein] CTD PMID:20888384 Deoxycorticosterone acetate increases expression EXP 6480464 Desoxycorticosterone Acetate results in increased expression of EDN1 protein CTD PMID:23089228 Deoxycorticosterone acetate multiple interactions EXP 6480464 [Desoxycorticosterone Acetate co-treated with Sodium Chloride more ... CTD PMID:23089228 more ... desferrioxamine B increases expression EXP 6480464 Deferoxamine results in increased expression of EDN1 protein CTD PMID:9357851 dexamethasone decreases expression ISO EDN1 (Homo sapiens) 6480464 Dexamethasone results in decreased expression of EDN1 mRNA CTD PMID:12206003 dexamethasone increases expression ISO Edn1 (Mus musculus) 6480464 Dexamethasone results in increased expression of EDN1 mRNA CTD PMID:22733784 dexamethasone multiple interactions ISO Edn1 (Mus musculus) 6480464 [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of EDN1 mRNA more ... CTD PMID:12407540 and PMID:16054899 dextran sulfate multiple interactions ISO Edn1 (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of EDN1 mRNA CTD PMID:29950665 diallyl disulfide multiple interactions ISO EDN1 (Homo sapiens) 6480464 diallyl disulfide inhibits the reaction [tobacco tar analog results in decreased expression of EDN1 mRNA] CTD PMID:36758788 diarsenic trioxide increases expression ISO EDN1 (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of EDN1 mRNA CTD PMID:26705709 dibenziodolium multiple interactions ISO Edn1 (Mus musculus) 6480464 diphenyleneiodonium inhibits the reaction [AGT protein results in increased expression of EDN1 mRNA] CTD PMID:17391658 dibenziodolium multiple interactions ISO EDN1 (Homo sapiens) 6480464 diphenyleneiodonium inhibits the reaction [Glucose promotes the reaction [EDN1 protein results in increased chemical synthesis of Inositol 1 more ... CTD PMID:20691780 dibenziodolium multiple interactions EXP 6480464 diphenyleneiodonium inhibits the reaction [EDN1 protein results in increased oxidation of PTPN11 protein] and diphenyleneiodonium inhibits the reaction [EDN1 protein results in increased phosphorylation of and results in increased activity of EGFR protein] CTD PMID:16391241 dibenzo[a,l]pyrene decreases expression ISO EDN1 (Homo sapiens) 6480464 dibenzo(a and l)pyrene results in decreased expression of EDN1 mRNA CTD PMID:31255691 dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of EDN1 mRNA CTD PMID:21266533 dibutyl phthalate multiple interactions EXP 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of EDN1 mRNA CTD PMID:31199487 dibutyl phthalate increases expression ISO Edn1 (Mus musculus) 6480464 Dibutyl Phthalate results in increased expression of EDN1 mRNA CTD PMID:17361019 and PMID:21266533 diclofenac multiple interactions ISO Edn1 (Mus musculus) 6480464 Diclofenac inhibits the reaction [EDN1 protein results in decreased transport of Potassium] CTD PMID:15083534 diethyl phthalate multiple interactions EXP 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of EDN1 mRNA CTD PMID:31199487 diisobutyl phthalate multiple interactions EXP 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of EDN1 mRNA CTD PMID:31199487 diisononyl phthalate multiple interactions EXP 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of EDN1 mRNA CTD PMID:31199487 dimethylarsinic acid multiple interactions ISO Edn1 (Mus musculus) 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of EDN1 mRNA CTD PMID:34876320 dimethylarsinous acid increases expression ISO EDN1 (Homo sapiens) 6480464 dimethylarsinous acid results in increased expression of EDN1 mRNA CTD PMID:23876855 dioxygen increases expression ISO Edn1 (Mus musculus) 6480464 Oxygen deficiency results in increased expression of EDN1 mRNA more ... CTD PMID:10939628 more ... dioxygen increases expression ISO EDN1 (Homo sapiens) 6480464 Oxygen deficiency results in increased expression of EDN1 mRNA and Oxygen deficiency results in increased expression of EDN1 protein CTD PMID:10939628 more ... dioxygen increases expression EXP 6480464 Oxygen deficiency results in increased expression of EDN1 mRNA and Oxygen deficiency results in increased expression of EDN1 protein CTD PMID:22860425 more ... dioxygen multiple interactions ISO Edn1 (Mus musculus) 6480464 [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of EDN1 mRNA more ... CTD PMID:16980344 more ... dioxygen increases secretion ISO EDN1 (Homo sapiens) 6480464 Oxygen deficiency results in increased secretion of EDN1 protein CTD PMID:21926265 and PMID:24557580 dioxygen multiple interactions ISO EDN1 (Homo sapiens) 6480464 caffeic acid phenethyl ester inhibits the reaction [Oxygen deficiency results in increased expression of EDN1 mRNA] more ... CTD PMID:10939628 more ... dioxygen multiple interactions EXP 6480464 [Ozone co-treated with Oxygen] inhibits the reaction [[Desoxycorticosterone Acetate co-treated with Sodium Chloride] results in increased expression of EDN1 mRNA] more ... CTD PMID:12969895 more ... diprotium oxide affects export ISO Edn1 (Mus musculus) 6480464 EDN1 protein affects the export of Water CTD PMID:16340664 dorsomorphin multiple interactions ISO EDN1 (Homo sapiens) 6480464 [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 doxorubicin increases activity ISO EDN1 (Homo sapiens) 6480464 Doxorubicin results in increased activity of EDN1 protein CTD PMID:7665224 doxorubicin increases expression ISO Edn1 (Mus musculus) 6480464 Doxorubicin results in increased expression of EDN1 mRNA and Doxorubicin results in increased expression of EDN1 protein CTD PMID:17974986 and PMID:18321777 doxorubicin multiple interactions ISO Edn1 (Mus musculus) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Doxorubicin results in increased expression of EDN1 mRNA] more ... CTD PMID:17974986 and PMID:18321777 doxorubicin multiple interactions EXP 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Doxorubicin results in increased expression of EDN1 mRNA] more ... CTD PMID:14736733 and PMID:17974986 doxorubicin increases expression EXP 6480464 Doxorubicin results in increased expression of EDN1 mRNA and Doxorubicin results in increased expression of EDN1 protein CTD PMID:11589785 more ... doxorubicin multiple interactions ISO EDN1 (Homo sapiens) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Doxorubicin results in increased expression of EDN1 mRNA] and RTKI cpd inhibits the reaction [Doxorubicin results in increased expression of EDN1 mRNA] CTD PMID:17974986 doxorubicin increases expression ISO EDN1 (Homo sapiens) 6480464 Doxorubicin results in increased expression of EDN1 protein CTD PMID:17974986 and PMID:7969316 dydrogesterone multiple interactions ISO EDN1 (Homo sapiens) 6480464 Dydrogesterone affects the reaction [Estradiol results in decreased expression of EDN1 protein] CTD PMID:12385860 EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor decreases secretion ISO EDN1 (Homo sapiens) 6480464 Angiotensin-Converting Enzyme Inhibitors results in decreased secretion of EDN1 protein CTD PMID:19079593 elemental carbon decreases activity EXP 6480464 Carbon analog results in decreased activity of EDN1 protein CTD PMID:20214918 enalapril multiple interactions EXP 6480464 Enalapril inhibits the reaction [Puromycin Aminonucleoside results in increased expression of EDN1 mRNA] CTD PMID:9175058 enalaprilat dihydrate decreases secretion ISO EDN1 (Homo sapiens) 6480464 Enalaprilat results in decreased secretion of EDN1 protein CTD PMID:19079593 endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of EDN1 mRNA CTD PMID:29391264 entinostat multiple interactions ISO EDN1 (Homo sapiens) 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EDN1 mRNA CTD PMID:27188386 entinostat increases expression ISO EDN1 (Homo sapiens) 6480464 entinostat results in increased expression of EDN1 mRNA CTD PMID:26272509 ethanol multiple interactions EXP 6480464 cyclo(Trp-Asp-Pro-Val-Leu) affects the reaction [Ethanol affects the activity of EDN1 protein] and nymphayol inhibits the reaction [Ethanol results in increased expression of EDN1 protein] CTD PMID:16651399 and PMID:25289771 ethanol increases expression EXP 6480464 Ethanol results in increased expression of EDN1 protein CTD PMID:25289771 ethanol increases expression ISO Edn1 (Mus musculus) 6480464 Ethanol results in increased expression of EDN1 mRNA CTD PMID:12193144 ethanol affects activity EXP 6480464 Ethanol affects the activity of EDN1 protein CTD PMID:16651399 etoposide multiple interactions ISO EDN1 (Homo sapiens) 6480464 EDN1 mutant form inhibits the reaction [VEGFC protein results in decreased susceptibility to Etoposide] CTD PMID:24184161 fenofibrate multiple interactions EXP 6480464 EDN1 protein promotes the reaction [Fenofibrate promotes the reaction [NFATC4 protein binds to PPARA protein]] more ... CTD PMID:22198280 fenofibrate multiple interactions ISO Edn1 (Mus musculus) 6480464 Fenofibrate affects the reaction [[AHR protein affects the susceptibility to AGT protein] which affects the expression of EDN1 mRNA] CTD PMID:31016362 fluoranthene multiple interactions ISO Edn1 (Mus musculus) 6480464 [1-methylanthracene co-treated with fluoranthene] results in increased expression of EDN1 mRNA CTD PMID:28329830 folic acid decreases expression ISO Edn1 (Mus musculus) 6480464 Folic Acid results in decreased expression of EDN1 mRNA CTD PMID:25629700 formaldehyde increases expression ISO EDN1 (Homo sapiens) 6480464 Formaldehyde results in increased expression of EDN1 mRNA CTD PMID:17938736 formaldehyde decreases expression ISO EDN1 (Homo sapiens) 6480464 Formaldehyde results in decreased expression of EDN1 mRNA CTD PMID:27664576 fructose increases response to substance EXP 6480464 Fructose results in increased susceptibility to EDN1 protein CTD PMID:9869011 fructose increases expression EXP 6480464 Fructose results in increased expression of EDN1 mRNA and Fructose results in increased expression of EDN1 protein modified form CTD PMID:11172478 more ... fructose multiple interactions EXP 6480464 KLK1 protein inhibits the reaction [Fructose results in increased expression of EDN1 mRNA] more ... CTD PMID:14568997 and PMID:25108154 fulvestrant multiple interactions ISO EDN1 (Homo sapiens) 6480464 [fulvestrant co-treated with Tamoxifen co-treated with ZD4054] results in decreased expression of EDN1 mRNA CTD PMID:19943105 furan increases expression EXP 6480464 furan results in increased expression of EDN1 mRNA CTD PMID:27387713 geldanamycin increases expression ISO EDN1 (Homo sapiens) 6480464 geldanamycin results in increased expression of EDN1 mRNA CTD PMID:26705709 gemcitabine decreases expression ISO EDN1 (Homo sapiens) 6480464 Gemcitabine results in decreased expression of EDN1 protein CTD PMID:20531411 genistein multiple interactions ISO EDN1 (Homo sapiens) 6480464 Genistein affects the reaction [cobaltous chloride promotes the reaction [HIF1A protein binds to ARNT protein binds to EDN1 promoter]] more ... CTD PMID:10939628 genistein increases methylation EXP 6480464 Genistein results in increased methylation of EDN1 gene CTD PMID:28505145 genistein decreases expression ISO EDN1 (Homo sapiens) 6480464 Genistein results in decreased expression of EDN1 mRNA CTD PMID:26865667 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of EDN1 mRNA and Gentamicins results in increased expression of EDN1 protein CTD PMID:10607017 more ... Gingerenone A increases expression ISO EDN1 (Homo sapiens) 6480464 gingerenone A results in increased expression of EDN1 mRNA CTD PMID:35326237 glucose multiple interactions ISO EDN1 (Homo sapiens) 6480464 carvedilol inhibits the reaction [Glucose results in increased expression of EDN1 mRNA] more ... CTD PMID:16428915 more ... glucose decreases expression ISO EDN1 (Homo sapiens) 6480464 Glucose results in decreased expression of EDN1 mRNA CTD PMID:31655124 glucose increases expression EXP 6480464 Glucose results in increased expression of EDN1 protein CTD PMID:26891083 glucose increases expression ISO EDN1 (Homo sapiens) 6480464 Glucose results in increased expression of EDN1 mRNA and Glucose results in increased expression of EDN1 protein CTD PMID:16428915 more ... glucose multiple interactions EXP 6480464 Glucose affects the reaction [EDN1 protein affects the abundance of and affects the localization of Calcium] more ... CTD PMID:12821678 and PMID:26891083 glyburide multiple interactions EXP 6480464 Glyburide inhibits the reaction [natakalim inhibits the reaction [Isoproterenol results in increased expression of EDN1 mRNA]] and Glyburide inhibits the reaction [natakalim inhibits the reaction [Isoproterenol results in increased expression of EDN1 protein]] CTD PMID:27890915 glycidol decreases expression EXP 6480464 glycidol results in decreased expression of EDN1 mRNA CTD PMID:24915197 glycoursodeoxycholic acid decreases expression ISO EDN1 (Homo sapiens) 6480464 glycoursodeoxycholic acid results in decreased expression of EDN1 protein CTD PMID:15556138 GW 4064 decreases expression EXP 6480464 GW 4064 results in decreased expression of EDN1 mRNA CTD PMID:16357303 heparin multiple interactions ISO EDN1 (Homo sapiens) 6480464 Heparin inhibits the reaction [F2 protein results in increased expression of EDN1 mRNA] and Heparin inhibits the reaction [F2 protein results in increased secretion of EDN1 protein] CTD PMID:7509996 and PMID:8408661 heparin decreases expression ISO EDN1 (Homo sapiens) 6480464 Heparin results in decreased expression of EDN1 mRNA CTD PMID:7509996 and PMID:8408661 heparin multiple interactions EXP 6480464 Heparin inhibits the reaction [EDN1 protein results in increased abundance of Calcium] more ... CTD PMID:1443220 heparin decreases secretion ISO EDN1 (Homo sapiens) 6480464 Heparin results in decreased secretion of EDN1 protein CTD PMID:7509996 and PMID:8408661 hexadecanoic acid increases expression ISO EDN1 (Homo sapiens) 6480464 Palmitic Acid results in increased expression of EDN1 mRNA and Palmitic Acid results in increased expression of EDN1 protein CTD PMID:16895544 hexadecanoic acid multiple interactions ISO EDN1 (Homo sapiens) 6480464 Agmatine inhibits the reaction [Palmitic Acid results in decreased expression of EDN1 protein] CTD PMID:35747990 hexadecanoic acid decreases expression ISO EDN1 (Homo sapiens) 6480464 Palmitic Acid results in decreased expression of EDN1 protein CTD PMID:35747990 histamine multiple interactions ISO EDN1 (Homo sapiens) 6480464 EDN1 protein results in decreased activity of [Atropine co-treated with Histamine] CTD PMID:12906840 homocysteine multiple interactions ISO EDN1 (Homo sapiens) 6480464 Zeranol inhibits the reaction [Homocysteine affects the expression of EDN1 protein] CTD PMID:16757814 homocysteine affects expression ISO EDN1 (Homo sapiens) 6480464 Homocysteine affects the expression of EDN1 protein CTD PMID:16757814 hydralazine multiple interactions EXP 6480464 Hydralazine inhibits the reaction [Nitric Oxide deficiency results in increased expression of EDN1 mRNA] CTD PMID:16326922 hydrochlorothiazide multiple interactions EXP 6480464 Hydrochlorothiazide inhibits the reaction [Nitric Oxide deficiency results in increased expression of EDN1 mRNA] CTD PMID:16326922 hydrogen chloride increases expression EXP 6480464 Hydrochloric Acid results in increased expression of EDN1 protein CTD PMID:19262391 hydrogen peroxide multiple interactions EXP 6480464 CAT protein inhibits the reaction [Hydrogen Peroxide results in decreased expression of EDN1 protein] CTD PMID:9357851 hydrogen peroxide affects expression ISO EDN1 (Homo sapiens) 6480464 Hydrogen Peroxide affects the expression of EDN1 mRNA CTD PMID:20044591 and PMID:23410634 hydrogen peroxide increases secretion ISO EDN1 (Homo sapiens) 6480464 Hydrogen Peroxide results in increased secretion of EDN1 protein CTD PMID:14623829 and PMID:20021702 hydrogen peroxide multiple interactions ISO EDN1 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of EDN1 mRNA] more ... CTD PMID:11755377 more ... hydrogen peroxide increases expression ISO EDN1 (Homo sapiens) 6480464 Hydrogen Peroxide results in increased expression of EDN1 mRNA and Hydrogen Peroxide results in increased expression of EDN1 protein CTD PMID:11755377 more ... hydrogen peroxide decreases expression EXP 6480464 Hydrogen Peroxide results in decreased expression of EDN1 protein CTD PMID:9357851 hydrogen sulfide increases expression ISO Edn1 (Mus musculus) 6480464 Hydrogen Sulfide results in increased expression of EDN1 mRNA CTD PMID:31843631 hydroquinone decreases expression ISO EDN1 (Homo sapiens) 6480464 hydroquinone results in decreased expression of EDN1 mRNA CTD PMID:31256213 ICI 118551 multiple interactions ISO EDN1 (Homo sapiens) 6480464 ICI 118551 inhibits the reaction [olodaterol results in decreased expression of EDN1 mRNA] CTD PMID:22796455 indometacin increases expression ISO EDN1 (Homo sapiens) 6480464 Indomethacin results in increased expression of EDN1 mRNA CTD PMID:16984733 indometacin increases expression EXP 6480464 Indomethacin results in increased expression of EDN1 protein CTD PMID:10423059 more ... indometacin decreases activity ISO EDN1 (Homo sapiens) 6480464 EDN1 protein results in decreased activity of Indomethacin CTD PMID:12906840 indometacin multiple interactions ISO EDN1 (Homo sapiens) 6480464 BQ 788 inhibits the reaction [EDN1 protein results in decreased activity of Indomethacin] and cyclo(Trp-Asp-Pro-Val-Leu) inhibits the reaction [EDN1 protein results in decreased activity of Indomethacin] CTD PMID:12906840 indometacin multiple interactions EXP 6480464 EDN1 protein inhibits the reaction [phosphoramidon inhibits the reaction [Indomethacin results in increased activity of ECE1 protein]] more ... CTD PMID:10423059 more ... indometacin decreases secretion ISO EDN1 (Homo sapiens) 6480464 Indomethacin results in decreased secretion of EDN1 protein CTD PMID:16133044 iodixanol increases expression EXP 6480464 iodixanol results in increased expression of EDN1 protein CTD PMID:21354280 iopromide increases expression EXP 6480464 iopromide results in increased expression of EDN1 protein CTD PMID:21354280 irbesartan affects response to substance ISO EDN1 (Homo sapiens) 6480464 EDN1 gene polymorphism affects the susceptibility to irbesartan CTD PMID:15188945 iron atom multiple interactions EXP 6480464 [Iron co-treated with Diethylnitrosamine] results in increased expression of EDN1 protein and Copper promotes the reaction [[Iron co-treated with Diethylnitrosamine] results in increased expression of EDN1 protein] CTD PMID:20302851 iron(0) multiple interactions EXP 6480464 [Iron co-treated with Diethylnitrosamine] results in increased expression of EDN1 protein and Copper promotes the reaction [[Iron co-treated with Diethylnitrosamine] results in increased expression of EDN1 protein] CTD PMID:20302851 iron(III) citrate decreases expression ISO EDN1 (Homo sapiens) 6480464 ferric citrate results in decreased expression of EDN1 mRNA CTD PMID:29959986 isoprenaline multiple interactions EXP 6480464 Cyclosporine inhibits the reaction [Isoproterenol results in increased activity of EDN1 promoter] more ... CTD PMID:11435416 more ... isoprenaline increases activity EXP 6480464 Isoproterenol results in increased activity of EDN1 promoter CTD PMID:11435416 isoprenaline increases expression EXP 6480464 Isoproterenol results in increased expression of EDN1 mRNA and Isoproterenol results in increased expression of EDN1 protein CTD PMID:27174236 more ... isoquinoline-1,5-diol decreases expression EXP 6480464 1 more ... CTD PMID:12824290 isorhamnetin multiple interactions EXP 6480464 3-methylquercetin inhibits the reaction [EDN1 protein results in increased expression of NCF1 mRNA] and 3-methylquercetin inhibits the reaction [EDN1 protein results in increased expression of NCF1 protein] CTD PMID:18436224 isosorbide dinitrate multiple interactions ISO EDN1 (Homo sapiens) 6480464 [Isosorbide Dinitrate co-treated with Plant Preparations] results in decreased expression of EDN1 mRNA CTD PMID:15719745 ivermectin multiple interactions ISO EDN1 (Homo sapiens) 6480464 Ivermectin inhibits the reaction [EDN1 protein results in increased expression of NPPB mRNA] and Ivermectin inhibits the reaction [EDN1 protein results in increased expression of NPPB protein] CTD PMID:28942281 KT 5823 multiple interactions EXP 6480464 KT 5823 inhibits the reaction [EDN1 protein results in decreased secretion of Norepinephrine] more ... CTD PMID:12184995 and PMID:16389725 L-ascorbic acid multiple interactions ISO EDN1 (Homo sapiens) 6480464 [Tretinoin co-treated with Ascorbic Acid] results in increased expression of EDN1 mRNA CTD PMID:16443354 L-mimosine increases expression ISO EDN1 (Homo sapiens) 6480464 Mimosine results in increased expression of EDN1 mRNA and Mimosine results in increased expression of EDN1 protein CTD PMID:25469848 L-mimosine increases expression EXP 6480464 Mimosine results in increased expression of EDN1 mRNA and Mimosine results in increased expression of EDN1 protein CTD PMID:25469848 lamivudine increases secretion ISO EDN1 (Homo sapiens) 6480464 Lamivudine results in increased secretion of EDN1 protein CTD PMID:23640862 lamivudine multiple interactions ISO EDN1 (Homo sapiens) 6480464 coenzyme Q10 inhibits the reaction [Lamivudine results in increased secretion of EDN1 protein] CTD PMID:23640862 leflunomide increases expression ISO Edn1 (Mus musculus) 6480464 leflunomide results in increased expression of EDN1 mRNA CTD PMID:19751817 leukotriene C4 increases expression ISO EDN1 (Homo sapiens) 6480464 Leukotriene C4 results in increased expression of EDN1 mRNA and Leukotriene C4 results in increased expression of EDN1 protein CTD PMID:11372388 leukotriene C4 multiple interactions ISO EDN1 (Homo sapiens) 6480464 zafirlukast inhibits the reaction [Leukotriene C4 results in increased expression of EDN1 mRNA] and zafirlukast inhibits the reaction [Leukotriene C4 results in increased expression of EDN1 protein] CTD PMID:11372388 levamisole decreases expression ISO EDN1 (Homo sapiens) 6480464 Levamisole results in decreased expression of EDN1 mRNA CTD PMID:11139434 linalool increases expression ISO EDN1 (Homo sapiens) 6480464 linalool results in increased expression of EDN1 mRNA CTD PMID:19922762 linoleic acid decreases expression ISO EDN1 (Homo sapiens) 6480464 Linoleic Acid results in decreased expression of EDN1 mRNA and Linoleic Acid results in decreased expression of EDN1 protein CTD PMID:16895544 lipopolysaccharide increases expression EXP 6480464 Lipopolysaccharides results in increased expression of EDN1 mRNA CTD PMID:26694894 lipopolysaccharide multiple interactions ISO EDN1 (Homo sapiens) 6480464 [S-(1 more ... CTD PMID:35811015 lipopolysaccharide increases expression ISO EDN1 (Homo sapiens) 6480464 Lipopolysaccharides results in increased expression of EDN1 mRNA CTD PMID:35811015 lipopolysaccharide increases expression ISO Edn1 (Mus musculus) 6480464 Lipopolysaccharides results in increased expression of EDN1 mRNA CTD PMID:21355878 lipopolysaccharide multiple interactions EXP 6480464 5 more ... CTD PMID:26694894 lisinopril dihydrate decreases secretion ISO EDN1 (Homo sapiens) 6480464 Lisinopril results in decreased secretion of EDN1 protein CTD PMID:19079593 losartan decreases expression ISO EDN1 (Homo sapiens) 6480464 Losartan results in decreased expression of EDN1 protein CTD PMID:11369837 losartan decreases expression EXP 6480464 Losartan results in decreased expression of EDN1 mRNA and Losartan results in decreased expression of EDN1 protein CTD PMID:16191423 and PMID:18971572 losartan multiple interactions EXP 6480464 Losartan inhibits the reaction [Nitroglycerin results in increased expression of EDN1 protein] CTD PMID:12901495 losartan multiple interactions ISO EDN1 (Homo sapiens) 6480464 Losartan inhibits the reaction [AGT protein modified form results in increased expression of EDN1 protein] CTD PMID:17666345 LY294002 multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [EDN1 protein results in increased activity of RPS6KB1 protein] CTD PMID:12411397 Magnolol multiple interactions EXP 6480464 magnolol inhibits the reaction [Monocrotaline results in increased expression of EDN1 protein] CTD PMID:30466619 malathion increases expression ISO EDN1 (Homo sapiens) 6480464 Malathion results in increased expression of EDN1 mRNA CTD PMID:37047231 manganese(II) chloride decreases expression EXP 6480464 manganese chloride results in decreased expression of EDN1 mRNA CTD PMID:28801915 Meglumine sodium amidotrizoate increases expression EXP 6480464 urovision results in increased expression of EDN1 protein CTD PMID:9413771 melphalan increases expression ISO EDN1 (Homo sapiens) 6480464 Melphalan results in increased expression of EDN1 protein CTD PMID:18548196 menadione increases expression ISO EDN1 (Homo sapiens) 6480464 Vitamin K 3 results in increased expression of EDN1 mRNA CTD PMID:12414654 menadione affects expression ISO EDN1 (Homo sapiens) 6480464 Vitamin K 3 affects the expression of EDN1 mRNA CTD PMID:20044591 and PMID:23410634 mercury dibromide multiple interactions ISO EDN1 (Homo sapiens) 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EDN1 mRNA CTD PMID:27188386 mercury dichloride multiple interactions EXP 6480464 candesartan cilexetil inhibits the reaction [Mercuric Chloride results in increased expression of EDN1 mRNA] and pimagedine inhibits the reaction [Mercuric Chloride results in increased expression of EDN1 mRNA] CTD PMID:9853001 mercury dichloride increases expression EXP 6480464 Mercuric Chloride results in increased expression of EDN1 mRNA and Mercuric Chloride results in increased expression of EDN1 protein CTD PMID:9788586 and PMID:9853001 metformin multiple interactions EXP 6480464 Metformin inhibits the reaction [Fructose results in increased expression of EDN1 protein] CTD PMID:25108154 metformin multiple interactions ISO Edn1 (Mus musculus) 6480464 Metformin inhibits the reaction [IL13 protein results in increased expression of EDN1 mRNA] CTD PMID:26497364 methotrexate increases expression ISO EDN1 (Homo sapiens) 6480464 Methotrexate results in increased expression of EDN1 mRNA CTD PMID:21678067 methoxychlor increases methylation EXP 6480464 Methoxychlor results in increased methylation of EDN1 gene CTD PMID:23303685 methyl 2-methylpropyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate decreases expression ISO EDN1 (Homo sapiens) 6480464 Nisoldipine results in decreased expression of EDN1 protein CTD PMID:8742913 methyl beta-cyclodextrin multiple interactions ISO Edn1 (Mus musculus) 6480464 methyl-beta-cyclodextrin inhibits the reaction [EDN1 protein affects the localization of CD38 protein] CTD PMID:23940720 methylarsonic acid multiple interactions ISO Edn1 (Mus musculus) 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of EDN1 mRNA CTD PMID:34876320 methylisothiazolinone increases expression ISO EDN1 (Homo sapiens) 6480464 2-methyl-4-isothiazolin-3-one results in increased expression of EDN1 mRNA CTD PMID:31629900 methylmercury chloride increases expression ISO EDN1 (Homo sapiens) 6480464 methylmercuric chloride results in increased expression of EDN1 mRNA CTD PMID:28001369 and PMID:31878059 methylmercury chloride multiple interactions ISO EDN1 (Homo sapiens) 6480464 HOXB13 protein affects the reaction [methylmercuric chloride results in increased expression of EDN1 mRNA] CTD PMID:31878059 metoprolol multiple interactions EXP 6480464 Metoprolol inhibits the reaction [Norepinephrine results in increased expression of EDN1 mRNA] CTD PMID:11435416 mevalonic acid multiple interactions ISO EDN1 (Homo sapiens) 6480464 Mevalonic Acid inhibits the reaction [Simvastatin results in decreased expression of EDN1 mRNA] and Mevalonic Acid inhibits the reaction [Simvastatin results in decreased expression of EDN1 protein] CTD PMID:18390205 Mibefradil multiple interactions EXP 6480464 Mibefradil inhibits the reaction [[Sodium Chloride and Dietary co-treated with Desoxycorticosterone] results in increased expression of EDN1 mRNA] CTD PMID:8934362 microcystin-LR increases expression ISO Edn1 (Mus musculus) 6480464 cyanoginosin LR results in increased expression of EDN1 mRNA CTD PMID:37342990 MK-2206 multiple interactions ISO EDN1 (Homo sapiens) 6480464 MK 2206 inhibits the reaction [RARRES2 protein results in increased expression of EDN1 protein] CTD PMID:34398343 MK-2206 decreases expression ISO EDN1 (Homo sapiens) 6480464 MK 2206 results in decreased expression of EDN1 protein CTD PMID:34398343 mono(2-ethylhexyl) phthalate increases expression EXP 6480464 mono-(2-ethylhexyl)phthalate results in increased expression of EDN1 mRNA CTD PMID:16809437 monocrotaline multiple interactions EXP 6480464 4-chlorobenzyltetrahydroberberine inhibits the reaction [Monocrotaline results in increased expression of EDN1 mRNA] more ... CTD PMID:16225752 more ... monocrotaline increases expression EXP 6480464 Monocrotaline results in increased expression of EDN1 mRNA and Monocrotaline results in increased expression of EDN1 protein CTD PMID:16225752 more ... montelukast multiple interactions EXP 6480464 montelukast inhibits the reaction [Cisplatin results in increased secretion of EDN1 protein] CTD PMID:28902463 N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide multiple interactions EXP 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [[EDN1 protein binds to and results in increased activity of EDNRB protein] which results in increased activity of NOS1 protein] and N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [EDN1 protein results in increased secretion of Norepinephrine] CTD PMID:14759557 and PMID:15245872 N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [EDN1 protein results in increased phosphorylation of and results in increased activity of EGFR protein] more ... CTD PMID:16261333 N-acetyl-L-cysteine multiple interactions ISO Edn1 (Mus musculus) 6480464 Acetylcysteine inhibits the reaction [Paraquat results in increased expression of EDN1 mRNA] CTD PMID:21765237 N-acetyl-L-cysteine multiple interactions ISO EDN1 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of EDN1 mRNA] and Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased secretion of EDN1 protein] CTD PMID:14623829 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases expression ISO EDN1 (Homo sapiens) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of EDN1 mRNA CTD PMID:18457675 N-nitrosodiethylamine multiple interactions EXP 6480464 [Iron co-treated with Diethylnitrosamine] results in increased expression of EDN1 protein and Copper promotes the reaction [[Iron co-treated with Diethylnitrosamine] results in increased expression of EDN1 protein] CTD PMID:20302851 naphthalene increases expression ISO Edn1 (Mus musculus) 6480464 naphthalene results in increased expression of EDN1 mRNA CTD PMID:18978301 nebivolol decreases expression ISO EDN1 (Homo sapiens) 6480464 Nebivolol results in decreased expression of EDN1 mRNA CTD PMID:11078433 nebivolol decreases secretion ISO EDN1 (Homo sapiens) 6480464 Nebivolol results in decreased secretion of EDN1 protein CTD PMID:11078433 nickel atom decreases expression ISO EDN1 (Homo sapiens) 6480464 Nickel results in decreased expression of EDN1 mRNA CTD PMID:25583101 nickel sulfate increases expression ISO EDN1 (Homo sapiens) 6480464 nickel sulfate results in increased expression of EDN1 mRNA CTD PMID:22714537 nicotine increases expression ISO Edn1 (Mus musculus) 6480464 Nicotine results in increased expression of EDN1 mRNA and Nicotine results in increased expression of EDN1 protein CTD PMID:33082140 nicotine multiple interactions ISO Edn1 (Mus musculus) 6480464 MIR98 mRNA inhibits the reaction [Nicotine results in increased expression of EDN1 mRNA] more ... CTD PMID:33082140 nicotinic acid-adenine dinucleotide phosphate increases metabolic processing ISO Edn1 (Mus musculus) 6480464 EDN1 protein results in increased metabolism of NAADP CTD PMID:23940720 nicotinic acid-adenine dinucleotide phosphate multiple interactions ISO Edn1 (Mus musculus) 6480464 NOX1 mutant form inhibits the reaction [EDN1 protein results in increased metabolism of NAADP] CTD PMID:23940720 nifedipine decreases activity EXP 6480464 Nifedipine results in decreased activity of EDN1 protein CTD PMID:12628492 nifedipine increases activity EXP 6480464 Nifedipine results in increased activity of EDN1 protein CTD PMID:7528292 nifedipine multiple interactions EXP 6480464 Nifedipine inhibits the reaction [Isoproterenol results in increased activity of EDN1 promoter] CTD PMID:11435416 nimesulide multiple interactions EXP 6480464 nimesulide inhibits the reaction [[KNG1 protein co-treated with F2 protein co-treated with EDN1 protein co-treated with Potassium Chloride] results in increased expression of TAC1 mRNA] more ... CTD PMID:21811393 nisoldipine decreases expression ISO EDN1 (Homo sapiens) 6480464 Nisoldipine results in decreased expression of EDN1 protein CTD PMID:8742913 nitric oxide increases chemical synthesis ISO EDN1 (Homo sapiens) 6480464 EDN1 protein results in increased chemical synthesis of Nitric Oxide CTD PMID:11187978 nitric oxide increases expression ISO Edn1 (Mus musculus) 6480464 Nitric Oxide results in increased expression of EDN1 mRNA CTD PMID:20197249 nitric oxide increases secretion EXP 6480464 Nitric Oxide results in increased secretion of EDN1 protein CTD PMID:15640287 nitric oxide increases expression EXP 6480464 Nitric Oxide deficiency results in increased expression of EDN1 mRNA CTD PMID:16326922 nitric oxide decreases activity EXP 6480464 Nitric Oxide deficiency results in decreased activity of EDN1 protein CTD PMID:16810074 nitric oxide increases abundance EXP 6480464 EDN1 protein results in increased abundance of Nitric Oxide CTD PMID:16380457 nitric oxide multiple interactions EXP 6480464 [EDN1 protein results in increased activity of EDNRB protein] which results in increased abundance of Nitric Oxide more ... CTD PMID:16326922 more ... nitric oxide increases expression ISO EDN1 (Homo sapiens) 6480464 Nitric Oxide results in increased expression of EDN1 protein CTD PMID:20929026 nitric oxide decreases expression ISO EDN1 (Homo sapiens) 6480464 Nitric Oxide results in decreased expression of EDN1 protein CTD PMID:15838368 nitrofen decreases expression ISO Edn1 (Mus musculus) 6480464 nitrofen results in decreased expression of EDN1 mRNA and nitrofen results in decreased expression of EDN1 protein CTD PMID:12407540 nitrofen increases expression EXP 6480464 nitrofen results in increased expression of EDN1 mRNA and nitrofen results in increased expression of EDN1 protein CTD PMID:10693666 more ... nitrofen multiple interactions ISO Edn1 (Mus musculus) 6480464 Dexamethasone inhibits the reaction [nitrofen results in decreased expression of EDN1 mRNA] and Dexamethasone inhibits the reaction [nitrofen results in decreased expression of EDN1 protein] CTD PMID:12407540 nitrogen dioxide multiple interactions ISO Edn1 (Mus musculus) 6480464 [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of EDN1 protein CTD PMID:30090456 nitroglycerin decreases expression ISO EDN1 (Homo sapiens) 6480464 Nitroglycerin results in decreased expression of EDN1 mRNA CTD PMID:12206003 nitroglycerin increases expression EXP 6480464 Nitroglycerin results in increased expression of EDN1 protein CTD PMID:12901495 nitroglycerin decreases expression EXP 6480464 Nitroglycerin results in decreased expression of EDN1 mRNA and Nitroglycerin results in decreased expression of EDN1 protein CTD PMID:11751199 nitroglycerin multiple interactions EXP 6480464 Losartan inhibits the reaction [Nitroglycerin results in increased expression of EDN1 protein] CTD PMID:12901495 nitroprusside multiple interactions EXP 6480464 Nitroprusside inhibits the reaction [[EDN1 protein binds to and results in increased activity of EDNRB protein] which results in decreased activity of TH protein] more ... CTD PMID:16023617 and PMID:16389725 Nutlin-3 increases expression ISO EDN1 (Homo sapiens) 6480464 nutlin 3 results in increased expression of EDN1 mRNA and nutlin 3 results in increased expression of EDN1 protein CTD PMID:19098008 ochratoxin A increases expression ISO EDN1 (Homo sapiens) 6480464 ochratoxin A results in increased expression of EDN1 mRNA CTD PMID:30559759 octadecanoic acid increases expression ISO EDN1 (Homo sapiens) 6480464 stearic acid results in increased expression of EDN1 mRNA and stearic acid results in increased expression of EDN1 protein CTD PMID:16895544 oleic acid decreases expression ISO EDN1 (Homo sapiens) 6480464 Oleic Acid results in decreased expression of EDN1 mRNA and Oleic Acid results in decreased expression of EDN1 protein CTD PMID:16895544 Olmesartan medoxomil decreases expression EXP 6480464 Olmesartan Medoxomil results in decreased expression of EDN1 mRNA CTD PMID:16336959 olodaterol multiple interactions ISO EDN1 (Homo sapiens) 6480464 2'-O-methyl-8-(4-chlorophenylthio)cAMP inhibits the reaction [olodaterol results in decreased expression of EDN1 mRNA] more ... CTD PMID:22483689 and PMID:22796455 olodaterol decreases expression ISO EDN1 (Homo sapiens) 6480464 olodaterol results in decreased expression of EDN1 mRNA CTD PMID:22796455 orotic acid increases expression EXP 6480464 Orotic Acid results in increased expression of EDN1 protein CTD PMID:25601987 oroxylin A multiple interactions EXP 6480464 5 more ... CTD PMID:26694894 ouabain increases expression EXP 6480464 Ouabain results in increased expression of EDN1 mRNA CTD PMID:15477225 ouabain decreases expression ISO EDN1 (Homo sapiens) 6480464 Ouabain results in decreased expression of EDN1 mRNA CTD PMID:28795476 Oxotremorine increases activity ISO EDN1 (Homo sapiens) 6480464 Oxotremorine results in increased activity of EDN1 protein CTD PMID:22796455 Oxotremorine multiple interactions ISO EDN1 (Homo sapiens) 6480464 [Oxotremorine co-treated with TGFB1 protein] results in increased expression of EDN1 mRNA more ... CTD PMID:22796455 Oxotremorine increases expression ISO EDN1 (Homo sapiens) 6480464 Oxotremorine results in increased expression of EDN1 mRNA CTD PMID:22796455 ozone multiple interactions EXP 6480464 [Ozone co-treated with Oxygen] inhibits the reaction [[Desoxycorticosterone Acetate co-treated with Sodium Chloride] results in increased expression of EDN1 mRNA] more ... CTD PMID:16081523 and PMID:26550192 ozone multiple interactions ISO Edn1 (Mus musculus) 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of EDN1 mRNA CTD PMID:34911549 ozone increases expression ISO EDN1 (Homo sapiens) 6480464 Ozone results in increased expression of EDN1 mRNA CTD PMID:27206323 ozone increases expression EXP 6480464 Ozone results in increased expression of EDN1 mRNA and Ozone results in increased expression of EDN1 protein CTD PMID:16081523 more ... panobinostat increases expression ISO EDN1 (Homo sapiens) 6480464 panobinostat results in increased expression of EDN1 mRNA CTD PMID:26272509 panobinostat multiple interactions ISO EDN1 (Homo sapiens) 6480464 [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EDN1 mRNA CTD PMID:27188386 paracetamol multiple interactions EXP 6480464 Acetaminophen inhibits the reaction [[KNG1 protein co-treated with F2 protein co-treated with EDN1 protein co-treated with Potassium Chloride] results in increased expression of TAC1 mRNA] and Acetaminophen inhibits the reaction [[KNG1 protein co-treated with F2 protein co-treated with EDN1 protein co-treated with Potassium Chloride] results in increased secretion of Dinoprostone] CTD PMID:21811393 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of EDN1 mRNA CTD PMID:33387578 paracetamol affects expression ISO Edn1 (Mus musculus) 6480464 Acetaminophen affects the expression of EDN1 mRNA CTD PMID:17562736 paraquat multiple interactions EXP 6480464 green tea extract AR25 inhibits the reaction [Paraquat results in increased expression of EDN1 mRNA] and green tea extract AR25 inhibits the reaction [Paraquat results in increased expression of EDN1 protein] CTD PMID:17235729 paraquat multiple interactions ISO Edn1 (Mus musculus) 6480464 Acetylcysteine inhibits the reaction [Paraquat results in increased expression of EDN1 mRNA] and Dapsone inhibits the reaction [Paraquat results in increased expression of EDN1 mRNA] CTD PMID:21765237 paraquat increases expression ISO Edn1 (Mus musculus) 6480464 Paraquat results in increased expression of EDN1 mRNA CTD PMID:21765237 paraquat increases expression EXP 6480464 Paraquat results in increased expression of EDN1 mRNA and Paraquat results in increased expression of EDN1 protein CTD PMID:17235729 paricalcitol multiple interactions EXP 6480464 paricalcitol inhibits the reaction [EDN1 protein results in increased expression of NPPA mRNA] and paricalcitol inhibits the reaction [EDN1 protein results in increased expression of PRKCA protein modified form] CTD PMID:21565836 PD123319 multiple interactions EXP 6480464 PD 123319 inhibits the reaction [AGT protein results in increased expression of EDN1 protein] CTD PMID:15007106 phenethyl caffeate multiple interactions ISO EDN1 (Homo sapiens) 6480464 caffeic acid phenethyl ester inhibits the reaction [Oxygen deficiency results in increased expression of EDN1 mRNA] and caffeic acid phenethyl ester inhibits the reaction [Oxygen deficiency results in increased expression of EDN1 protein] CTD PMID:21926265 phenethyl isothiocyanate decreases expression ISO EDN1 (Homo sapiens) 6480464 phenethyl isothiocyanate results in decreased expression of EDN1 mRNA CTD PMID:26678675 phenobarbital decreases expression ISO EDN1 (Homo sapiens) 6480464 Phenobarbital results in decreased expression of EDN1 mRNA CTD PMID:19084549 phenylephrine increases response to substance EXP 6480464 EDN1 protein results in increased susceptibility to Phenylephrine CTD PMID:20977430 phenylephrine increases expression EXP 6480464 Phenylephrine results in increased expression of EDN1 mRNA and Phenylephrine results in increased expression of EDN1 protein CTD PMID:10788492 and PMID:15220332 phenylephrine multiple interactions ISO EDN1 (Homo sapiens) 6480464 EP300 protein promotes the reaction [[Phenylephrine results in increased activity of GATA4 protein] which results in increased expression of EDN1 mRNA] CTD PMID:12724418 phenylephrine multiple interactions EXP 6480464 Phenylephrine promotes the reaction [GATA4 protein binds to EDN1 promoter] more ... CTD PMID:10788492 more ... phenylmercury acetate multiple interactions ISO EDN1 (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EDN1 mRNA CTD PMID:27188386 PhIP increases expression EXP 6480464 2-amino-1-methyl-6-phenylimidazo(4 and 5-b)pyridine results in increased expression of EDN1 mRNA CTD PMID:15215175 phosgene increases expression EXP 6480464 Phosgene results in increased expression of EDN1 protein CTD PMID:18645720 phosphoramide mustard increases expression EXP 6480464 phosphoramide mustard results in increased expression of EDN1 mRNA CTD PMID:27888070 phosphoramidon decreases expression EXP 6480464 phosphoramidon results in decreased expression of EDN1 protein CTD PMID:16391412 phosphoramidon multiple interactions EXP 6480464 EDN1 protein inhibits the reaction [phosphoramidon inhibits the reaction [Indomethacin results in increased activity of ECE1 protein]] more ... CTD PMID:11145282 and PMID:16280098 picrotoxin multiple interactions EXP 6480464 Picrotoxin inhibits the reaction [EDN1 protein results in decreased secretion of Norepinephrine] CTD PMID:12184995 potassium atom decreases transport ISO Edn1 (Mus musculus) 6480464 EDN1 protein results in decreased transport of Potassium CTD PMID:15083534 potassium atom multiple interactions ISO Edn1 (Mus musculus) 6480464 Diclofenac inhibits the reaction [EDN1 protein results in decreased transport of Potassium] CTD PMID:15083534 potassium chloride multiple interactions EXP 6480464 [19-oxo-11-deoxycorticosterone acetate co-treated with Potassium Chloride co-treated with Sodium Chloride] results in increased expression of EDN1 mRNA more ... CTD PMID:18823320 and PMID:21811393 potassium chromate decreases expression ISO EDN1 (Homo sapiens) 6480464 potassium chromate(VI) results in decreased expression of EDN1 mRNA CTD PMID:22714537 pravastatin decreases expression ISO EDN1 (Homo sapiens) 6480464 Pravastatin results in decreased expression of EDN1 protein CTD PMID:12105140 pravastatin decreases expression EXP 6480464 Pravastatin results in decreased expression of EDN1 mRNA and Pravastatin results in decreased expression of EDN1 protein CTD PMID:19812503 prazosin multiple interactions EXP 6480464 Prazosin inhibits the reaction [EDN1 protein results in increased expression of NPPA protein] and Prazosin inhibits the reaction [Phenylephrine results in increased expression of EDN1 protein] CTD PMID:12513686 and PMID:15007106 progesterone multiple interactions ISO EDN1 (Homo sapiens) 6480464 Progesterone inhibits the reaction [Estradiol results in increased expression of EDN1 mRNA] and Progesterone inhibits the reaction [Estradiol results in increased secretion of EDN1 protein] CTD PMID:21795739 progesterone increases expression ISO Edn1 (Mus musculus) 6480464 Progesterone results in increased expression of EDN1 mRNA CTD PMID:22238285 progesterone decreases expression EXP 6480464 Progesterone results in decreased expression of EDN1 mRNA CTD PMID:20726854 propofol decreases expression EXP 6480464 Propofol results in decreased expression of EDN1 protein CTD PMID:17470888 propofol multiple interactions ISO EDN1 (Homo sapiens) 6480464 Propofol inhibits the reaction [EDN1 protein affects the transport of Calcium] CTD PMID:9138053 prostaglandin E2 multiple interactions EXP 6480464 [KNG1 protein co-treated with F2 protein co-treated with EDN1 protein co-treated with Potassium Chloride] results in increased secretion of Dinoprostone more ... CTD PMID:21811393 prostaglandin E2 increases secretion ISO Edn1 (Mus musculus) 6480464 EDN1 protein results in increased secretion of Dinoprostone CTD PMID:16384872 quartz decreases expression ISO EDN1 (Homo sapiens) 6480464 Quartz results in decreased expression of EDN1 mRNA CTD PMID:27917503 quercetin multiple interactions ISO EDN1 (Homo sapiens) 6480464 Quercetin inhibits the reaction [Hydrogen Peroxide results in increased expression of EDN1 mRNA] more ... CTD PMID:11755377 and PMID:20021702 quercetin decreases expression ISO EDN1 (Homo sapiens) 6480464 Quercetin results in decreased expression of EDN1 mRNA CTD PMID:18234130 and PMID:20021702 quercetin decreases secretion ISO EDN1 (Homo sapiens) 6480464 Quercetin results in decreased secretion of EDN1 protein CTD PMID:20021702 quercetin increases expression ISO EDN1 (Homo sapiens) 6480464 Quercetin results in increased expression of EDN1 mRNA CTD PMID:21632981 quercetin multiple interactions EXP 6480464 Quercetin inhibits the reaction [EDN1 protein results in increased expression of NCF1 mRNA] and Quercetin inhibits the reaction [EDN1 protein results in increased expression of NCF1 protein] CTD PMID:18436224 quercetin multiple interactions ISO Edn1 (Mus musculus) 6480464 Quercetin inhibits the reaction [APOE gene mutant form results in increased expression of EDN1 protein] CTD PMID:20093625 quinapril hydrochloride decreases expression ISO EDN1 (Homo sapiens) 6480464 Quinapril results in decreased expression of EDN1 and Quinapril results in decreased expression of EDN1 protein CTD PMID:12149661 and PMID:12425201 reactive oxygen species increases abundance EXP 6480464 EDN1 protein results in increased abundance of Reactive Oxygen Species CTD PMID:16391241 and PMID:22431579 reactive oxygen species multiple interactions ISO EDN1 (Homo sapiens) 6480464 Reactive Oxygen Species results in increased phosphorylation of and results in increased activity of EDN1 protein CTD PMID:11603923 reactive oxygen species increases expression ISO EDN1 (Homo sapiens) 6480464 Reactive Oxygen Species results in increased expression of EDN1 protein CTD PMID:11603923 reactive oxygen species increases chemical synthesis EXP 6480464 EDN1 protein results in increased chemical synthesis of Reactive Oxygen Species CTD PMID:16271043 reactive oxygen species multiple interactions EXP 6480464 acetovanillone inhibits the reaction [EDN1 protein results in increased abundance of Reactive Oxygen Species] more ... CTD PMID:16391241 and PMID:22431579 rebaudioside A decreases expression ISO EDN1 (Homo sapiens) 6480464 rebaudioside A results in decreased expression of EDN1 mRNA CTD PMID:31655124 RES-701-1 multiple interactions EXP 6480464 RES 701-1 inhibits the reaction [EDN1 protein results in decreased secretion of NPY protein] CTD PMID:12234805 resveratrol multiple interactions ISO EDN1 (Homo sapiens) 6480464 [Coumestrol co-treated with resveratrol] results in decreased expression of EDN1 mRNA more ... CTD PMID:11755377 more ... resveratrol multiple interactions ISO Edn1 (Mus musculus) 6480464 [resveratrol co-treated with Catechin co-treated with caffeic acid] results in decreased expression of EDN1 mRNA CTD PMID:16806235 resveratrol decreases expression ISO Edn1 (Mus musculus) 6480464 resveratrol results in decreased expression of EDN1 mRNA CTD PMID:22935447 resveratrol decreases expression ISO EDN1 (Homo sapiens) 6480464 resveratrol results in decreased expression of EDN1 mRNA CTD PMID:14623829 more ... resveratrol decreases secretion ISO EDN1 (Homo sapiens) 6480464 resveratrol results in decreased secretion of EDN1 protein CTD PMID:14623829 and PMID:20021702 resveratrol decreases expression EXP 6480464 resveratrol results in decreased expression of EDN1 CTD PMID:16535856 resveratrol multiple interactions EXP 6480464 resveratrol inhibits the reaction [AGT protein results in increased expression of EDN1 mRNA] more ... CTD PMID:15878161 more ... rifampicin multiple interactions ISO EDN1 (Homo sapiens) 6480464 [Rifampin co-treated with NR1I2 protein] results in increased expression of EDN1 mRNA CTD PMID:21127053 Ro 31-8220 multiple interactions EXP 6480464 Ro 31-8220 inhibits the reaction [EDN1 protein results in increased phosphorylation of JUN protein] CTD PMID:12169099 rolipram increases activity EXP 6480464 Rolipram results in increased activity of EDN1 protein CTD PMID:15464066 rotenone multiple interactions EXP 6480464 Rotenone results in increased expression of and results in increased secretion of EDN1 protein CTD PMID:11707688 rotenone decreases expression ISO EDN1 (Homo sapiens) 6480464 Rotenone results in decreased expression of EDN1 mRNA CTD PMID:36586010 rotenone multiple interactions ISO EDN1 (Homo sapiens) 6480464 Rotenone inhibits the reaction [Acrolein results in increased expression of EDN1 protein] CTD PMID:22928487 rotenone increases expression EXP 6480464 Rotenone results in increased expression of EDN1 mRNA CTD PMID:11078378 and PMID:11707688 ruxolitinib decreases phosphorylation EXP 6480464 ruxolitinib results in decreased phosphorylation of EDN1 protein CTD PMID:30670587 S-(1,2-dichlorovinyl)-L-cysteine multiple interactions ISO EDN1 (Homo sapiens) 6480464 [S-(1 more ... CTD PMID:35811015 S-methyl-L-thiocitrulline multiple interactions EXP 6480464 S-methylthiocitrulline inhibits the reaction [EDN1 protein results in increased abundance of Nitric Oxide] CTD PMID:16380457 S-nitroso-N-acetyl-D-penicillamine increases secretion EXP 6480464 S-Nitroso-N-Acetylpenicillamine results in increased secretion of EDN1 protein CTD PMID:15640287 SB 203580 multiple interactions ISO EDN1 (Homo sapiens) 6480464 SB 203580 inhibits the reaction [cobaltous chloride results in increased secretion of EDN1 protein] more ... CTD PMID:18457675 more ... SB 203580 multiple interactions EXP 6480464 SB 203580 inhibits the reaction [EDN1 protein results in increased phosphorylation of CREB1 protein] CTD PMID:14741741 SB 431542 multiple interactions ISO EDN1 (Homo sapiens) 6480464 [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 sevoflurane affects expression EXP 6480464 sevoflurane affects the expression of EDN1 mRNA CTD PMID:15967596 sildenafil citrate multiple interactions ISO EDN1 (Homo sapiens) 6480464 Sildenafil Citrate inhibits the reaction [EDN1 protein results in increased expression of TRPC1 mRNA] CTD PMID:18818482 silicon dioxide decreases expression ISO EDN1 (Homo sapiens) 6480464 Silicon Dioxide analog results in decreased expression of EDN1 mRNA CTD PMID:25895662 silicon dioxide increases expression ISO EDN1 (Homo sapiens) 6480464 Silicon Dioxide results in increased expression of EDN1 mRNA CTD PMID:25351596 silicon dioxide increases expression ISO Edn1 (Mus musculus) 6480464 Silicon Dioxide results in increased expression of EDN1 mRNA CTD PMID:19073995 and PMID:33720480 silicon dioxide decreases expression ISO Edn1 (Mus musculus) 6480464 Silicon Dioxide results in decreased expression of EDN1 mRNA CTD PMID:30453980 silver atom increases expression ISO EDN1 (Homo sapiens) 6480464 Silver results in increased expression of EDN1 mRNA CTD PMID:26014281 silver(0) increases expression ISO EDN1 (Homo sapiens) 6480464 Silver results in increased expression of EDN1 mRNA CTD PMID:26014281 simvastatin decreases secretion ISO EDN1 (Homo sapiens) 6480464 Simvastatin results in decreased secretion of EDN1 protein CTD PMID:16375908 simvastatin decreases expression EXP 6480464 Simvastatin results in decreased expression of EDN1 mRNA CTD PMID:19099753 and PMID:21844074 simvastatin multiple interactions ISO EDN1 (Homo sapiens) 6480464 Mevalonic Acid inhibits the reaction [Simvastatin results in decreased expression of EDN1 mRNA] more ... CTD PMID:18390205 and PMID:20369390 simvastatin decreases expression ISO EDN1 (Homo sapiens) 6480464 Simvastatin results in decreased expression of EDN1 mRNA and Simvastatin results in decreased expression of EDN1 protein CTD PMID:18390205 simvastatin multiple interactions EXP 6480464 Simvastatin inhibits the reaction [EDN1 protein results in increased expression of CLCN3 protein] and Simvastatin inhibits the reaction [Monocrotaline results in increased expression of EDN1 mRNA] CTD PMID:20644009 and PMID:22022327 sirolimus multiple interactions EXP 6480464 Sirolimus inhibits the reaction [EDN1 protein results in increased activity of RPS6KB1 protein] and Sirolimus inhibits the reaction [EDN1 protein results in increased phosphorylation of EIF4EBP1 protein] CTD PMID:12411397 sodium arsenate multiple interactions ISO Edn1 (Mus musculus) 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of EDN1 mRNA CTD PMID:34876320 sodium arsenite increases expression ISO Edn1 (Mus musculus) 6480464 sodium arsenite results in increased expression of EDN1 protein CTD PMID:28470405 sodium arsenite multiple interactions ISO Edn1 (Mus musculus) 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of EDN1 mRNA CTD PMID:34876320 sodium arsenite decreases expression ISO EDN1 (Homo sapiens) 6480464 sodium arsenite results in decreased expression of EDN1 mRNA CTD PMID:34032870 sodium arsenite increases expression ISO EDN1 (Homo sapiens) 6480464 sodium arsenite results in increased expression of EDN1 mRNA CTD PMID:28470405 sodium arsenite multiple interactions ISO EDN1 (Homo sapiens) 6480464 RELA protein affects the reaction [sodium arsenite results in increased expression of EDN1 mRNA] more ... CTD PMID:28470405 sodium atom affects response to substance ISO Edn1 (Mus musculus) 6480464 EDN1 protein affects the susceptibility to Sodium CTD PMID:16340664 sodium atom affects export ISO Edn1 (Mus musculus) 6480464 EDN1 protein affects the export of Sodium CTD PMID:16340664 sodium chloride multiple interactions EXP 6480464 [19-oxo-11-deoxycorticosterone acetate co-treated with Potassium Chloride co-treated with Sodium Chloride] results in increased expression of EDN1 mRNA more ... CTD PMID:18823320 and PMID:26550192 sodium dodecyl sulfate increases expression ISO EDN1 (Homo sapiens) 6480464 Sodium Dodecyl Sulfate results in increased expression of EDN1 mRNA CTD PMID:31734321 sorafenib increases expression EXP 6480464 Sorafenib results in increased expression of EDN1 protein CTD PMID:33503445 stattic multiple interactions EXP 6480464 stattic inhibits the reaction [EDN1 protein results in increased expression of CCND1 mRNA] more ... CTD PMID:30670587 staurosporine decreases activity EXP 6480464 Staurosporine results in decreased activity of EDN1 protein CTD PMID:15464066 steviol decreases expression ISO EDN1 (Homo sapiens) 6480464 steviol results in decreased expression of EDN1 mRNA CTD PMID:31655124 stevioside decreases expression ISO EDN1 (Homo sapiens) 6480464 stevioside results in decreased expression of EDN1 mRNA CTD PMID:31655124 stilbene-4,4'-diol decreases secretion ISO EDN1 (Homo sapiens) 6480464 4 and 4'-dihydroxystilbene results in decreased secretion of EDN1 protein CTD PMID:21554123 stilbene-4,4'-diol decreases expression ISO EDN1 (Homo sapiens) 6480464 4 and 4'-dihydroxystilbene results in decreased expression of EDN1 mRNA CTD PMID:21554123 streptozocin multiple interactions EXP 6480464 Bezafibrate inhibits the reaction [Streptozocin results in increased expression of EDN1 mRNA] CTD PMID:12967931 streptozocin multiple interactions ISO EDN1 (Homo sapiens) 6480464 diphenyleneiodonium inhibits the reaction [Streptozocin promotes the reaction [EDN1 protein results in increased chemical synthesis of Inositol 1 more ... CTD PMID:20691780 streptozocin increases expression EXP 6480464 Streptozocin results in increased expression of EDN1 mRNA CTD PMID:12458661 and PMID:12967931 Sucralfate multiple interactions EXP 6480464 Sucralfate inhibits the reaction [Indomethacin results in increased expression of EDN1 protein] CTD PMID:10423059 sulfur dioxide increases expression EXP 6480464 Sulfur Dioxide results in increased expression of EDN1 mRNA and Sulfur Dioxide results in increased expression of EDN1 protein CTD PMID:20083630 sulfur dioxide multiple interactions ISO Edn1 (Mus musculus) 6480464 [Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of EDN1 protein CTD PMID:30090456 sunitinib decreases expression ISO EDN1 (Homo sapiens) 6480464 Sunitinib results in decreased expression of EDN1 mRNA CTD PMID:31533062 superoxide multiple interactions EXP 6480464 [EDN1 protein co-treated with Calcimycin] results in increased abundance of Superoxides more ... CTD PMID:20977430 superoxide multiple interactions ISO Edn1 (Mus musculus) 6480464 NOX1 mutant form inhibits the reaction [EDN1 protein results in increased abundance of Superoxides] CTD PMID:23940720 superoxide increases abundance ISO Edn1 (Mus musculus) 6480464 EDN1 protein results in increased abundance of Superoxides CTD PMID:23940720 superoxide increases abundance EXP 6480464 EDN1 protein results in increased abundance of Superoxides CTD PMID:20977430 tacrolimus hydrate increases expression EXP 6480464 Tacrolimus results in increased expression of EDN1 mRNA and Tacrolimus results in increased expression of EDN1 protein CTD PMID:9517403 and PMID:9931093 tamibarotene increases expression ISO EDN1 (Homo sapiens) 6480464 tamibarotene results in increased expression of EDN1 mRNA CTD PMID:15498508 tamoxifen multiple interactions ISO EDN1 (Homo sapiens) 6480464 [fulvestrant co-treated with Tamoxifen co-treated with ZD4054] results in decreased expression of EDN1 mRNA more ... CTD PMID:19943105 tamoxifen affects expression ISO Edn1 (Mus musculus) 6480464 Tamoxifen affects the expression of EDN1 mRNA CTD PMID:17555576 tamoxifen increases expression ISO EDN1 (Homo sapiens) 6480464 Tamoxifen results in increased expression of EDN1 mRNA CTD PMID:19943105 Tanshinone I multiple interactions EXP 6480464 tanshinone inhibits the reaction [Oxygen deficiency results in increased expression of EDN1 protein] CTD PMID:28985491 tauroursodeoxycholic acid decreases expression ISO EDN1 (Homo sapiens) 6480464 ursodoxicoltaurine results in decreased expression of EDN1 protein CTD PMID:15556138 telmisartan multiple interactions EXP 6480464 telmisartan inhibits the reaction [Daunorubicin results in increased expression of EDN1 protein] CTD PMID:20888384 temozolomide increases expression ISO EDN1 (Homo sapiens) 6480464 Temozolomide results in increased expression of EDN1 mRNA CTD PMID:31758290 tenofovir disoproxil fumarate increases secretion ISO EDN1 (Homo sapiens) 6480464 Tenofovir results in increased secretion of EDN1 protein CTD PMID:23640862 tenofovir disoproxil fumarate multiple interactions ISO EDN1 (Homo sapiens) 6480464 coenzyme Q10 inhibits the reaction [Tenofovir results in increased secretion of EDN1 protein] CTD PMID:23640862 teprenone decreases expression EXP 6480464 geranylgeranylacetone results in decreased expression of EDN1 protein CTD PMID:16324314 tert-butyl hydroperoxide increases expression ISO EDN1 (Homo sapiens) 6480464 tert-Butylhydroperoxide results in increased expression of EDN1 mRNA CTD PMID:12414654 tert-butyl hydroperoxide affects expression ISO EDN1 (Homo sapiens) 6480464 tert-Butylhydroperoxide affects the expression of EDN1 mRNA CTD PMID:23410634 testosterone multiple interactions ISO EDN1 (Homo sapiens) 6480464 [Testosterone co-treated with Calcitriol] results in increased expression of EDN1 mRNA CTD PMID:21592394 testosterone increases expression ISO Edn1 (Mus musculus) 6480464 Testosterone deficiency results in increased expression of EDN1 mRNA CTD PMID:33848595 testosterone increases expression ISO EDN1 (Homo sapiens) 6480464 Testosterone results in increased expression of EDN1 mRNA CTD PMID:21592394 testosterone affects expression EXP 6480464 Testosterone affects the expression of EDN1 mRNA CTD PMID:12122504 and PMID:14616470 tetrachloromethane multiple interactions EXP 6480464 Carbon Tetrachloride promotes the reaction [EDN1 protein results in increased abundance of Platelet Activating Factor] more ... CTD PMID:12632514 and PMID:18205269 tetrachloromethane increases activity EXP 6480464 Carbon Tetrachloride results in increased activity of EDN1 protein CTD PMID:25858767 tetrachloromethane multiple interactions ISO Edn1 (Mus musculus) 6480464 Lipids inhibits the reaction [Carbon Tetrachloride results in increased expression of EDN1 protein] CTD PMID:25445725 tetrachloromethane increases expression ISO Edn1 (Mus musculus) 6480464 Carbon Tetrachloride results in increased expression of EDN1 mRNA and Carbon Tetrachloride results in increased expression of EDN1 protein CTD PMID:17484886 more ... tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of EDN1 mRNA and Carbon Tetrachloride results in increased expression of EDN1 protein CTD PMID:12575897 more ... tetracosanoic acid increases expression ISO EDN1 (Homo sapiens) 6480464 lignoceric acid results in increased expression of EDN1 protein CTD PMID:16895544 tetraphene increases expression ISO Edn1 (Mus musculus) 6480464 benz(a)anthracene results in increased expression of EDN1 mRNA CTD PMID:26377693 theophylline multiple interactions ISO EDN1 (Homo sapiens) 6480464 Theophylline inhibits the reaction [CSF2 protein results in increased expression of EDN1 mRNA] CTD PMID:10374451 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of EDN1 mRNA CTD PMID:23411599 and PMID:34492290 thymidine increases uptake ISO EDN1 (Homo sapiens) 6480464 EDN1 protein results in increased uptake of Thymidine CTD PMID:10100047 tiotropium bromide multiple interactions ISO EDN1 (Homo sapiens) 6480464 Tiotropium Bromide inhibits the reaction [Oxotremorine results in increased expression of EDN1 mRNA] CTD PMID:22796455 Tiron multiple interactions ISO Edn1 (Mus musculus) 6480464 1 more ... CTD PMID:17391658 titanium dioxide increases expression ISO Edn1 (Mus musculus) 6480464 titanium dioxide results in increased expression of EDN1 mRNA CTD PMID:23409001 and PMID:23557971 titanium dioxide multiple interactions ISO Edn1 (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of EDN1 mRNA CTD PMID:29950665 torcetrapib multiple interactions EXP 6480464 torcetrapib affects the expression of and affects the activity of EDN1 protein CTD PMID:21920972 trans-caffeic acid multiple interactions ISO Edn1 (Mus musculus) 6480464 [resveratrol co-treated with Catechin co-treated with caffeic acid] results in decreased expression of EDN1 mRNA CTD PMID:16806235 trans-stilbene-4,4'-diol decreases secretion ISO EDN1 (Homo sapiens) 6480464 4 and 4'-dihydroxystilbene results in decreased secretion of EDN1 protein CTD PMID:21554123 trans-stilbene-4,4'-diol decreases expression ISO EDN1 (Homo sapiens) 6480464 4 and 4'-dihydroxystilbene results in decreased expression of EDN1 mRNA CTD PMID:21554123 triadimefon decreases expression ISO EDN1 (Homo sapiens) 6480464 triadimefon results in decreased expression of EDN1 mRNA CTD PMID:26705709 tributylstannane increases expression EXP 6480464 tributyltin results in increased expression of EDN1 mRNA CTD PMID:31129395 trichloroethene increases expression ISO Edn1 (Mus musculus) 6480464 Trichloroethylene results in increased expression of EDN1 mRNA and Trichloroethylene results in increased expression of EDN1 protein CTD PMID:32763311 trichloroethene multiple interactions ISO Edn1 (Mus musculus) 6480464 N-(benzyloxycarbonyl)-phenylalanyl-tyrosinal inhibits the reaction [Trichloroethylene results in increased expression of EDN1 mRNA] and N-(benzyloxycarbonyl)-phenylalanyl-tyrosinal inhibits the reaction [Trichloroethylene results in increased expression of EDN1 protein] CTD PMID:32763311 trichostatin A decreases expression ISO EDN1 (Homo sapiens) 6480464 trichostatin A results in decreased expression of EDN1 mRNA CTD PMID:24935251 trichostatin A multiple interactions ISO EDN1 (Homo sapiens) 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EDN1 mRNA CTD PMID:27188386 trichostatin A increases expression ISO EDN1 (Homo sapiens) 6480464 trichostatin A results in increased expression of EDN1 mRNA CTD PMID:24935251 more ... triclosan decreases expression ISO EDN1 (Homo sapiens) 6480464 Triclosan results in decreased expression of EDN1 mRNA CTD PMID:30510588 troglitazone multiple interactions ISO EDN1 (Homo sapiens) 6480464 troglitazone inhibits the reaction [AGT protein modified form results in increased expression of EDN1 protein] CTD PMID:17666345 tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate multiple interactions ISO EDN1 (Homo sapiens) 6480464 EDN1 protein results in decreased activity of [Atropine co-treated with Histamine] CTD PMID:12906840 tyrphostin AG 1478 multiple interactions EXP 6480464 RTKI cpd inhibits the reaction [Doxorubicin results in increased expression of EDN1 mRNA] more ... CTD PMID:16261333 and PMID:17974986 tyrphostin AG 1478 multiple interactions ISO Edn1 (Mus musculus) 6480464 RTKI cpd inhibits the reaction [Doxorubicin results in increased expression of EDN1 mRNA] CTD PMID:17974986 tyrphostin AG 1478 multiple interactions ISO EDN1 (Homo sapiens) 6480464 RTKI cpd inhibits the reaction [Doxorubicin results in increased expression of EDN1 mRNA] CTD PMID:17974986 U-73122 multiple interactions EXP 6480464 1-(6-((3-methoxyestra-1 more ... CTD PMID:14759557 and PMID:15245872 urethane decreases expression ISO EDN1 (Homo sapiens) 6480464 Urethane results in decreased expression of EDN1 mRNA CTD PMID:28818685 ursodeoxycholic acid decreases expression ISO EDN1 (Homo sapiens) 6480464 Ursodeoxycholic Acid results in decreased expression of EDN1 mRNA and Ursodeoxycholic Acid results in decreased expression of EDN1 protein CTD PMID:15556138 ursolic acid multiple interactions ISO Edn1 (Mus musculus) 6480464 Ursolic Acid inhibits the reaction [Choline results in increased expression of EDN1 protein] CTD PMID:27567547 valproic acid affects expression ISO Edn1 (Mus musculus) 6480464 Valproic Acid affects the expression of EDN1 mRNA CTD PMID:17292431 valproic acid increases expression ISO EDN1 (Homo sapiens) 6480464 Valproic Acid results in increased expression of EDN1 mRNA CTD PMID:23179753 more ... valproic acid affects expression ISO EDN1 (Homo sapiens) 6480464 Valproic Acid affects the expression of EDN1 mRNA CTD PMID:25979313 valsartan multiple interactions EXP 6480464 [Valsartan co-treated with benazepril] results in decreased expression of EDN1 protein CTD PMID:11136700 vanadyl sulfate increases expression ISO EDN1 (Homo sapiens) 6480464 vanadyl sulfate results in increased expression of EDN1 mRNA CTD PMID:16330358 verapamil multiple interactions ISO EDN1 (Homo sapiens) 6480464 Verapamil inhibits the reaction [EDN1 protein results in increased expression of NPPB mRNA] and Verapamil inhibits the reaction [EDN1 protein results in increased expression of NPPB protein] CTD PMID:28942281 vinclozolin increases methylation EXP 6480464 vinclozolin results in increased methylation of EDN1 promoter CTD PMID:22570695 water affects export ISO Edn1 (Mus musculus) 6480464 EDN1 protein affects the export of Water CTD PMID:16340664 wortmannin multiple interactions ISO Edn1 (Mus musculus) 6480464 wortmannin inhibits the reaction [EDN1 protein inhibits the reaction [TNF protein results in increased expression of NOS2 protein]] CTD PMID:12839867 Y-27632 multiple interactions EXP 6480464 Y 27632 inhibits the reaction [Phenylephrine results in increased expression of EDN1 mRNA] CTD PMID:11739382 zafirlukast multiple interactions ISO EDN1 (Homo sapiens) 6480464 zafirlukast inhibits the reaction [Leukotriene C4 results in increased expression of EDN1 mRNA] and zafirlukast inhibits the reaction [Leukotriene C4 results in increased expression of EDN1 protein] CTD PMID:11372388 zafirlukast decreases expression ISO EDN1 (Homo sapiens) 6480464 zafirlukast results in decreased expression of EDN1 protein CTD PMID:12781059 zidovudine multiple interactions ISO EDN1 (Homo sapiens) 6480464 coenzyme Q10 inhibits the reaction [Zidovudine results in increased secretion of EDN1 protein] CTD PMID:23640862 zidovudine increases secretion ISO EDN1 (Homo sapiens) 6480464 Zidovudine results in increased secretion of EDN1 protein CTD PMID:23640862 zinc atom multiple interactions ISO EDN1 (Homo sapiens) 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of EDN1 mRNA CTD PMID:18593933 zinc(0) multiple interactions ISO EDN1 (Homo sapiens) 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of EDN1 mRNA CTD PMID:18593933 zoledronic acid increases expression ISO EDN1 (Homo sapiens) 6480464 zoledronic acid results in increased expression of EDN1 mRNA CTD PMID:24714768