Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	2532
Species:	Rattus norvegicus
RGD Object:	Gene
Symbol:	Edn1
Name:	endothelin 1

Acc ID:	CHEBI:144421
Term:	iron(III) citrate
Definition:	An iron chelate resulting from the combination of iron(3+) and citrate(3-).
Chemical ID:	MESH:C025314

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
Edn1	decreases expression	ISO	EDN1 (Homo sapiens)	6480464	CTD	ferric citrate results in decreased expression of EDN1 mRNA	PMID:29959986

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.