Cdkn1a (cyclin-dependent kinase inhibitor 1A) - Rat Genome Database

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Gene: Cdkn1a (cyclin-dependent kinase inhibitor 1A) Rattus norvegicus
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Symbol: Cdkn1a
Name: cyclin-dependent kinase inhibitor 1A
RGD ID: 69328
Description: Predicted to enable several functions, including cyclin binding activity; enzyme binding activity; and protein kinase regulator activity. Involved in several processes, including intestinal epithelial cell maturation; response to corticosterone; and response to hyperoxia. Located in nucleus and perinuclear region of cytoplasm. Biomarker of autosomal dominant polycystic kidney disease; hypertension (multiple); lipoid nephrosis; liver benign neoplasm; and pre-malignant neoplasm. Human ortholog(s) of this gene implicated in high grade glioma; ocular hypertension; oral mucosa leukoplakia; oral squamous cell carcinoma; and primary open angle glaucoma. Orthologous to human CDKN1A (cyclin dependent kinase inhibitor 1A); PARTICIPATES IN G1/S transition pathway; Notch signaling pathway; nuclear factor, erythroid 2 like 2 signaling pathway; INTERACTS WITH (+)-alpha-tocopherol; (+)-schisandrin B; (S)-colchicine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Cip1; cyclin-dependent kinase inhibitor 1; cyclin-dependent kinase inhibitor 1A (P21); cyclin-dependent kinase inhibitor 1A (p21, Cip1); UV96; Waf1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Is Marker For: Strains:   BUF.ACI-(D20Img2-Cdkn1a)/Ncc   ACI.BUF-(D20Img2-Cdkn1a)/Ncc  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2207,149,177 - 7,159,727 (+)NCBI
Rnor_6.0 Ensembl206,351,458 - 6,358,864 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0206,348,422 - 6,358,864 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0208,592,437 - 8,602,879 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4207,376,325 - 7,386,778 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1207,379,612 - 7,385,803 (+)NCBI
Celera208,699,290 - 8,709,718 (+)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model