(+)-catechin multiple interactions ISO RGD:1606037 6480464 [Catechin co-treated with Grape Seed Proanthocyanidins] results in increased expression of DNMT3B mRNA CTD PMID:24763279 (-)-epigallocatechin 3-gallate multiple interactions ISO RGD:1606037 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of DNMT3B mRNA CTD PMID:22079256 (-)-epigallocatechin 3-gallate increases expression ISO RGD:1606037 6480464 epigallocatechin gallate results in increased expression of DNMT3B mRNA CTD PMID:25839702 1-chloro-2,4-dinitrobenzene decreases expression ISO RGD:1606037 6480464 Dinitrochlorobenzene results in decreased expression of DNMT3B mRNA CTD PMID:25236440 17beta-estradiol multiple interactions EXP 6480464 [Testosterone co-treated with Estradiol] affects the reaction [bisphenol A results in increased expression of DNMT3B mRNA], [Testosterone co-treated with Estradiol] affects the reaction [estradiol-17 beta-benzoate results in increased expression of DNMT3B mRNA] CTD PMID:22109888 17beta-estradiol multiple interactions ISO RGD:1606037 6480464 Estradiol promotes the reaction [DNMT3B protein binds to COMT promoter] more ... CTD PMID:30684530 17beta-estradiol increases expression ISO RGD:1606037 6480464 Estradiol results in increased expression of DNMT3B mRNA CTD PMID:30684530 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO RGD:1551604 6480464 [2 more ... CTD PMID:25510870 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO RGD:1551604 6480464 [2 more ... CTD PMID:25510870 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid decreases expression ISO RGD:1606037 6480464 2 more ... CTD PMID:32068100 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:1551604 6480464 Tetrachlorodibenzodioxin results in decreased expression of DNMT3B mRNA CTD PMID:19770486 , PMID:28922406 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of DNMT3B mRNA CTD PMID:26455773 , PMID:32109520 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1606037 6480464 Resveratrol inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [DNMT3B protein binds to BRCA1 promoter]], Tetrachlorodibenzodioxin promotes the reaction [DNMT3B protein binds to BRCA1 promoter] CTD PMID:22197621 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:1606037 6480464 Tetrachlorodibenzodioxin results in decreased expression of DNMT3B mRNA CTD PMID:20106945 , PMID:21632981 3,3'-diindolylmethane decreases expression ISO RGD:1606037 6480464 3, 3'-diindolylmethane results in decreased expression of DNMT3B mRNA CTD PMID:24466240 3,4-methylenedioxymethamphetamine increases expression ISO RGD:1551604 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in increased expression of DNMT3B mRNA CTD PMID:26251327 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:1551604 6480464 [Dexamethasone co-treated with INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with perfluorooctanoic acid] results in increased expression of DNMT3B mRNA CTD PMID:29094436 3-phenylprop-2-enal decreases expression ISO RGD:1606037 6480464 cinnamic aldehyde results in decreased expression of DNMT3B mRNA CTD PMID:17178418 4,4'-sulfonyldiphenol increases expression ISO RGD:1606037 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of DNMT3B mRNA, bis(4-hydroxyphenyl)sulfone results in increased expression of DNMT3B protein CTD PMID:25912373 , PMID:32105160 4,4'-sulfonyldiphenol multiple interactions ISO RGD:1606037 6480464 bis(4-hydroxyphenyl)sulfone promotes the reaction [ESR1 protein binds to DNMT3B promoter] more ... CTD PMID:32105160 4,4'-sulfonyldiphenol increases expression ISO RGD:1551604 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of DNMT3B mRNA, bis(4-hydroxyphenyl)sulfone results in increased expression of DNMT3B protein CTD PMID:29741722 , PMID:31532523 4-nonylphenol multiple interactions ISO RGD:1606037 6480464 [4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of DNMT3B mRNA more ... CTD PMID:23626723 4-tert-Octylphenol multiple interactions ISO RGD:1606037 6480464 [4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of DNMT3B mRNA more ... CTD PMID:23626723 5-aza-2'-deoxycytidine decreases response to substance ISO RGD:1606037 6480464 DNMT3B gene mutant form results in decreased susceptibility to Decitabine CTD PMID:23300844 5-aza-2'-deoxycytidine multiple interactions ISO RGD:1606037 6480464 Decitabine affects the reaction [hydroquinone affects the expression of DNMT3B mRNA] more ... CTD PMID:16887905 more ... 5-aza-2'-deoxycytidine decreases expression ISO RGD:1551604 6480464 Decitabine results in decreased expression of DNMT3B protein CTD PMID:19679824 5-aza-2'-deoxycytidine affects response to substance ISO RGD:1606037 6480464 DNMT3B protein affects the susceptibility to Decitabine CTD PMID:17991895 5-aza-2'-deoxycytidine multiple interactions ISO RGD:1551604 6480464 Decitabine inhibits the reaction [Particulate Matter promotes the reaction [[ovalbumin-alum co-treated with Ovalbumin] results in increased expression of DNMT3B protein]], Decitabine inhibits the reaction [Particulate Matter results in increased expression of DNMT3B protein] CTD PMID:30481581 5-aza-2'-deoxycytidine affects expression EXP 6480464 Decitabine affects the expression of DNMT3B mRNA CTD PMID:24447120 5-aza-2'-deoxycytidine multiple interactions EXP 6480464 Decitabine inhibits the reaction [Dust results in increased expression of DNMT3B mRNA] CTD PMID:30815999 5-aza-2'-deoxycytidine decreases expression ISO RGD:1606037 6480464 Decitabine results in decreased expression of DNMT3B mRNA, Decitabine results in decreased expression of DNMT3B protein CTD PMID:17991895 more ... 5-aza-2'-deoxycytidine affects expression ISO RGD:1606037 6480464 [Decitabine affects the expression of DNMT3B protein] which affects the expression of CDKN1A mRNA more ... CTD PMID:18544619 5-fluorouracil decreases expression ISO RGD:1551604 6480464 Fluorouracil results in decreased expression of DNMT3B protein CTD PMID:21296659 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of DNMT3B mRNA CTD PMID:24780913 8-hydroxy-2'-deoxyguanosine affects abundance ISO RGD:1606037 6480464 DNMT3B gene SNP affects the abundance of 8-Hydroxy-2'-Deoxyguanosine CTD PMID:19896490 acetic acid decreases expression ISO RGD:1551604 6480464 Acetic Acid results in decreased expression of DNMT3B protein CTD PMID:21296659 acrylamide decreases expression ISO RGD:1551604 6480464 Acrylamide results in decreased expression of DNMT3B mRNA CTD PMID:30807115 aflatoxin B1 decreases methylation ISO RGD:1606037 6480464 Aflatoxin B1 results in decreased methylation of DNMT3B exon CTD PMID:30157460 all-trans-retinoic acid decreases expression ISO RGD:1551604 6480464 Tretinoin results in decreased expression of DNMT3B mRNA CTD PMID:16788091 all-trans-retinoic acid decreases expression ISO RGD:1606037 6480464 Tretinoin results in decreased expression of DNMT3B mRNA CTD PMID:17273765 , PMID:21934132 amphetamine decreases expression EXP 6480464 Amphetamine results in decreased expression of DNMT3B mRNA CTD PMID:30779732 arsane affects metabolic processing ISO RGD:1606037 6480464 DNMT3B gene polymorphism affects the metabolism of Arsenic CTD PMID:21247820 arsane multiple interactions ISO RGD:1606037 6480464 DNMT3B gene SNP affects the reaction [Arsenic affects the methylation of CDH1 promoter] CTD PMID:30220071 arsenic atom affects metabolic processing ISO RGD:1606037 6480464 DNMT3B gene polymorphism affects the metabolism of Arsenic CTD PMID:21247820 arsenic atom multiple interactions ISO RGD:1606037 6480464 DNMT3B gene SNP affects the reaction [Arsenic affects the methylation of CDH1 promoter] CTD PMID:30220071 arsenous acid decreases activity ISO RGD:1606037 6480464 Arsenic Trioxide results in decreased activity of DNMT3B protein CTD PMID:20596618 arsenous acid decreases expression ISO RGD:1606037 6480464 Arsenic Trioxide results in decreased expression of DNMT3B, Arsenic Trioxide results in decreased expression of DNMT3B mRNA CTD PMID:12667347 more ... arsenous acid decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of DNMT3B mRNA CTD PMID:29223816 arsenous acid decreases expression ISO RGD:1551604 6480464 Arsenic Trioxide results in decreased expression of DNMT3B protein CTD PMID:19679824 arsenous acid increases expression ISO RGD:1606037 6480464 Arsenic Trioxide results in increased expression of DNMT3B mRNA CTD PMID:25534098 azathioprine decreases expression ISO RGD:1606037 6480464 Azathioprine results in decreased expression of DNMT3B mRNA CTD PMID:22623647 benzo[a]pyrene increases mutagenesis ISO RGD:1606037 6480464 Benzo(a)pyrene results in increased mutagenesis of DNMT3B gene CTD PMID:25435355 benzo[a]pyrene decreases methylation ISO RGD:1606037 6480464 Benzo(a)pyrene results in decreased methylation of DNMT3B 5' UTR CTD PMID:27901495 benzo[a]pyrene affects methylation ISO RGD:1606037 6480464 Benzo(a)pyrene affects the methylation of DNMT3B promoter CTD PMID:27901495 benzo[a]pyrene decreases methylation ISO RGD:1551604 6480464 Benzo(a)pyrene results in decreased methylation of DNMT3B intron CTD PMID:27901495 benzo[a]pyrene decreases expression ISO RGD:1606037 6480464 Benzo(a)pyrene results in decreased expression of DNMT3B mRNA CTD PMID:27901495 benzo[a]pyrene decreases expression ISO RGD:1551604 6480464 Benzo(a)pyrene results in decreased expression of DNMT3B mRNA CTD PMID:19770486 , PMID:21715664 benzophenanthridine decreases expression ISO RGD:1606037 6480464 Benzophenanthridines analog results in decreased expression of DNMT3B mRNA CTD PMID:23117580 berberine decreases expression ISO RGD:1606037 6480464 Berberine results in decreased expression of DNMT3B mRNA CTD PMID:27311644 bis(2-chloroethyl) sulfide increases expression ISO RGD:1551604 6480464 Mustard Gas results in increased expression of DNMT3B mRNA CTD PMID:15674844 bis(2-chloroethyl) sulfide decreases expression ISO RGD:1551604 6480464 Mustard Gas results in decreased expression of DNMT3B mRNA CTD PMID:26392148 bis(2-ethylhexyl) phthalate increases expression ISO RGD:1551604 6480464 Diethylhexyl Phthalate results in increased expression of DNMT3B mRNA CTD PMID:20335514 bis(2-ethylhexyl) phthalate affects expression ISO RGD:1551604 6480464 Diethylhexyl Phthalate affects the expression of DNMT3B mRNA CTD PMID:32628958 bis(2-ethylhexyl) phthalate decreases expression ISO RGD:1551604 6480464 Diethylhexyl Phthalate results in decreased expression of DNMT3B mRNA CTD PMID:31211961 bis(2-ethylhexyl) phthalate increases expression ISO RGD:1606037 6480464 Diethylhexyl Phthalate results in increased expression of DNMT3B protein CTD PMID:31163220 bis(2-ethylhexyl) phthalate decreases expression ISO RGD:1606037 6480464 Diethylhexyl Phthalate results in decreased expression of DNMT3B mRNA CTD PMID:31163220 bis(2-ethylhexyl) phthalate increases expression EXP 6480464 Diethylhexyl Phthalate results in increased expression of DNMT3B mRNA, Diethylhexyl Phthalate results in increased expression of DNMT3B protein CTD PMID:25280772 bisphenol A decreases expression ISO RGD:1551604 6480464 bisphenol A results in decreased expression of DNMT3B mRNA, bisphenol A results in decreased expression of DNMT3B protein CTD PMID:22131059 more ... bisphenol A multiple interactions ISO RGD:1606037 6480464 bisphenol A promotes the reaction [ESR1 protein binds to DNMT3B promoter] more ... CTD PMID:32105160 bisphenol A affects methylation ISO RGD:1551604 6480464 bisphenol A affects the methylation of DNMT3B promoter CTD PMID:27334623 bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of DNMT3B gene CTD PMID:28505145 bisphenol A decreases methylation ISO RGD:1606037 6480464 bisphenol A results in decreased methylation of DNMT3B promoter CTD PMID:27271280 bisphenol A increases expression ISO RGD:1606037 6480464 bisphenol A results in increased expression of DNMT3B mRNA, bisphenol A results in increased expression of DNMT3B protein CTD PMID:27685785 , PMID:32105160 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of DNMT3B mRNA CTD PMID:25181051 , PMID:25748669 bisphenol A multiple interactions EXP 6480464 [Testosterone co-treated with Estradiol] affects the reaction [bisphenol A results in increased expression of DNMT3B mRNA] CTD PMID:22109888 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of DNMT3B mRNA, bisphenol A results in increased expression of DNMT3B protein CTD PMID:21827818 more ... bisphenol A increases expression ISO RGD:1551604 6480464 bisphenol A results in increased expression of DNMT3B mRNA, bisphenol A results in increased expression of DNMT3B protein CTD PMID:23535407 more ... bisphenol A multiple interactions ISO RGD:1551604 6480464 Fulvestrant inhibits the reaction [bisphenol A results in decreased expression of DNMT3B mRNA], Fulvestrant inhibits the reaction [bisphenol A results in increased expression of DNMT3B mRNA] CTD PMID:22131059 , PMID:30892605 bromobenzene increases expression EXP 6480464 bromobenzene results in increased expression of DNMT3B mRNA CTD PMID:32479839 bromochloroacetic acid decreases expression ISO RGD:1551604 6480464 bromochloroacetic acid results in decreased expression of DNMT3B protein CTD PMID:21296659 buta-1,3-diene decreases expression ISO RGD:1551604 6480464 1, 3-butadiene results in decreased expression of DNMT3B mRNA CTD PMID:30552462 Butylparaben increases expression EXP 6480464 butylparaben results in increased expression of DNMT3B mRNA CTD PMID:26888303 cadmium atom affects expression ISO RGD:1606037 6480464 Cadmium affects the expression of DNMT3B mRNA CTD PMID:22382075 cadmium dichloride increases expression ISO RGD:1606037 6480464 Cadmium Chloride results in increased expression of DNMT3B mRNA CTD PMID:17938735 , PMID:25448810 cadmium dichloride increases expression ISO RGD:1551604 6480464 Cadmium Chloride results in increased expression of DNMT3B protein CTD PMID:27984135 caffeine increases expression EXP 6480464 Caffeine results in increased expression of DNMT3B mRNA CTD PMID:25868845 , PMID:30423288 calcitriol decreases expression ISO RGD:1606037 6480464 Calcitriol results in decreased expression of DNMT3B mRNA CTD PMID:21592394 calcitriol multiple interactions ISO RGD:1606037 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of DNMT3B mRNA CTD PMID:21592394 carbon nanotube increases expression ISO RGD:1551604 6480464 Nanotubes, Carbon results in increased expression of DNMT3B mRNA CTD PMID:25620056 choline multiple interactions ISO RGD:1551604 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DNMT3B protein CTD PMID:20548288 cisplatin decreases response to substance ISO RGD:1606037 6480464 DNMT3B protein results in decreased susceptibility to Cisplatin CTD PMID:18314485 cisplatin multiple interactions ISO RGD:1606037 6480464 [Cisplatin co-treated with jinfukang] results in increased expression of DNMT3B mRNA CTD PMID:27392435 cisplatin increases phosphorylation ISO RGD:1551604 6480464 Cisplatin results in increased phosphorylation of DNMT3B protein CTD PMID:22006019 cocaine decreases expression ISO RGD:1551604 6480464 Cocaine results in decreased expression of DNMT3B mRNA, Cocaine results in decreased expression of DNMT3B protein CTD PMID:22438930 cocaine multiple interactions ISO RGD:1551604 6480464 Methionine inhibits the reaction [Cocaine results in decreased expression of DNMT3B mRNA], Methionine inhibits the reaction [Cocaine results in decreased expression of DNMT3B protein] CTD PMID:22438930 copper(II) sulfate increases expression ISO RGD:1606037 6480464 Copper Sulfate results in increased expression of DNMT3B mRNA CTD PMID:19549813 curcumin decreases expression ISO RGD:1606037 6480464 Curcumin results in decreased expression of DNMT3B mRNA CTD PMID:23593078 curcumin decreases expression ISO RGD:1551604 6480464 Curcumin analog results in decreased expression of DNMT3B protein CTD PMID:26991801 , PMID:29228771 cyclosporin A decreases expression ISO RGD:1606037 6480464 Cyclosporine results in decreased expression of DNMT3B mRNA CTD PMID:20106945 , PMID:27989131 cyclosporin A increases expression ISO RGD:1606037 6480464 Cyclosporine results in increased expression of DNMT3B mRNA CTD PMID:25562108 D-penicillamine multiple interactions ISO RGD:1551604 6480464 Penicillamine promotes the reaction [ATP7B protein mutant form results in decreased expression of DNMT3B mRNA] CTD PMID:22945834 DDT decreases expression EXP 6480464 DDT results in decreased expression of DNMT3B mRNA CTD PMID:19797855 desferrioxamine B decreases expression ISO RGD:1606037 6480464 Deferoxamine results in decreased expression of DNMT3B mRNA CTD PMID:23483119 desferrioxamine B increases expression ISO RGD:1606037 6480464 Deferoxamine results in increased expression of DNMT3B mRNA CTD PMID:23483119 dexamethasone multiple interactions ISO RGD:1551604 6480464 [Dexamethasone co-treated with INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with perfluorooctanoic acid] results in increased expression of DNMT3B mRNA CTD PMID:29094436 diarsenic trioxide decreases activity ISO RGD:1606037 6480464 Arsenic Trioxide results in decreased activity of DNMT3B protein CTD PMID:20596618 diarsenic trioxide decreases expression ISO RGD:1551604 6480464 Arsenic Trioxide results in decreased expression of DNMT3B protein CTD PMID:19679824 diarsenic trioxide increases expression ISO RGD:1606037 6480464 Arsenic Trioxide results in increased expression of DNMT3B mRNA CTD PMID:25534098 diarsenic trioxide decreases expression ISO RGD:1606037 6480464 Arsenic Trioxide results in decreased expression of DNMT3B, Arsenic Trioxide results in decreased expression of DNMT3B mRNA CTD PMID:12667347 more ... diarsenic trioxide decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of DNMT3B mRNA CTD PMID:29223816 dibenz[a,h]anthracene decreases expression ISO RGD:1551604 6480464 1 more ... CTD PMID:26377693 dibutyl phthalate decreases expression ISO RGD:1551604 6480464 Dibutyl Phthalate results in decreased expression of DNMT3B mRNA CTD PMID:21266533 dibutyl phthalate decreases expression EXP 6480464 Dibutyl Phthalate results in decreased expression of DNMT3B protein CTD PMID:26745512 dicrotophos increases expression ISO RGD:1606037 6480464 dicrotophos results in increased expression of DNMT3B mRNA CTD PMID:28302478 diethylstilbestrol increases expression ISO RGD:1551604 6480464 Diethylstilbestrol results in increased expression of DNMT3B mRNA CTD PMID:16714842 diphenylcyclopropenone decreases expression ISO RGD:1606037 6480464 diphenylcyclopropenone results in decreased expression of DNMT3B mRNA CTD PMID:25236440 dorsomorphin multiple interactions ISO RGD:1606037 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 endosulfan increases expression ISO RGD:1606037 6480464 Endosulfan results in increased expression of DNMT3B mRNA, Endosulfan results in increased expression of DNMT3B protein CTD PMID:29054638 endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of DNMT3B mRNA CTD PMID:29391264 entinostat decreases expression ISO RGD:1551604 6480464 entinostat results in decreased expression of DNMT3B protein CTD PMID:19679824 entinostat increases expression ISO RGD:1606037 6480464 entinostat results in increased expression of DNMT3B mRNA CTD PMID:26272509 entinostat multiple interactions ISO RGD:1606037 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of DNMT3B mRNA CTD PMID:27188386 ethanol multiple interactions ISO RGD:1551604 6480464 [Carbon Tetrachloride co-treated with Ethanol] results in decreased expression of DNMT3B mRNA, benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Ethanol results in increased degradation of DNMT3B protein] CTD PMID:23395981 , PMID:30517762 ethanol decreases expression ISO RGD:1551604 6480464 Ethanol results in decreased expression of DNMT3B protein CTD PMID:23395981 ethanol increases expression ISO RGD:1551604 6480464 Ethanol results in increased expression of DNMT3B mRNA CTD PMID:23395981 ethanol increases degradation ISO RGD:1551604 6480464 Ethanol results in increased degradation of DNMT3B protein CTD PMID:23395981 etoposide decreases response to substance ISO RGD:1606037 6480464 DNMT3B protein results in decreased susceptibility to Etoposide CTD PMID:18314485 folic acid affects expression ISO RGD:1606037 6480464 Folic Acid affects the expression of DNMT3B mRNA, Folic Acid affects the expression of DNMT3B protein CTD PMID:17311948 , PMID:26492244 folic acid decreases expression ISO RGD:1606037 6480464 Folic Acid results in decreased expression of DNMT3B mRNA CTD PMID:21867686 folic acid increases expression ISO RGD:1551604 6480464 Folic Acid results in increased expression of DNMT3B mRNA CTD PMID:26547318 folic acid decreases expression ISO RGD:1551604 6480464 Folic Acid results in decreased expression of DNMT3B mRNA CTD PMID:25629700 folic acid multiple interactions ISO RGD:1606037 6480464 APP protein affects the reaction [Folic Acid affects the expression of DNMT3B mRNA], APP protein affects the reaction [Folic Acid affects the expression of DNMT3B protein] CTD PMID:26492244 folic acid multiple interactions ISO RGD:1551604 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DNMT3B protein, Folic Acid affects the reaction [[APOE protein affects the susceptibility to Dietary Fats] which affects the expression of DNMT3B mRNA] CTD PMID:20548288 , PMID:28475147 formaldehyde decreases expression ISO RGD:1606037 6480464 Formaldehyde results in decreased expression of DNMT3B mRNA, Formaldehyde results in decreased expression of DNMT3B protein CTD PMID:21745553 fulvestrant multiple interactions ISO RGD:1551604 6480464 Fulvestrant inhibits the reaction [bisphenol A results in decreased expression of DNMT3B mRNA], Fulvestrant inhibits the reaction [bisphenol A results in increased expression of DNMT3B mRNA] CTD PMID:22131059 , PMID:30892605 fumonisin B1 decreases activity ISO RGD:1606037 6480464 fumonisin B1 results in decreased activity of DNMT3B protein CTD PMID:24280379 gemcitabine multiple interactions ISO RGD:1606037 6480464 [gemcitabine results in decreased susceptibility to gemcitabine] which results in increased expression of DNMT3B protein CTD PMID:25189999 genistein decreases expression ISO RGD:1606037 6480464 Genistein results in decreased expression of DNMT3B mRNA, Genistein results in decreased expression of DNMT3B protein CTD PMID:19221000 , PMID:23593078 genistein multiple interactions ISO RGD:1606037 6480464 Genistein promotes the reaction [DNMT3B protein binds to COMT promoter] CTD PMID:30684530 gibberellin A3 decreases expression EXP 6480464 gibberellic acid results in decreased expression of DNMT3B mRNA CTD PMID:31733319 glycine betaine decreases expression ISO RGD:1551604 6480464 Betaine results in decreased expression of DNMT3B mRNA CTD PMID:22945834 guggulsterone decreases expression ISO RGD:1606037 6480464 pregna-4 more ... CTD PMID:23593078 hydrogen peroxide decreases response to substance ISO RGD:1606037 6480464 DNMT3B protein results in decreased susceptibility to Hydrogen Peroxide CTD PMID:18314485 hydroquinone decreases expression ISO RGD:1606037 6480464 hydroquinone results in decreased expression of DNMT3B mRNA CTD PMID:22245671 hydroquinone multiple interactions ISO RGD:1606037 6480464 Decitabine affects the reaction [hydroquinone affects the expression of DNMT3B mRNA], trichostatin A affects the reaction [hydroquinone affects the expression of DNMT3B mRNA] CTD PMID:31899212 hydroquinone affects expression ISO RGD:1606037 6480464 hydroquinone affects the expression of DNMT3B mRNA CTD PMID:31899212 indole-3-methanol affects expression EXP 6480464 indole-3-carbinol affects the expression of DNMT3B mRNA CTD PMID:21396975 isoprenaline increases expression ISO RGD:1551604 6480464 Isoproterenol results in increased expression of DNMT3B mRNA CTD PMID:21335049 ketamine decreases expression EXP 6480464 Ketamine results in decreased expression of DNMT3B mRNA CTD PMID:20080153 L-methionine multiple interactions ISO RGD:1551604 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DNMT3B protein more ... CTD PMID:20548288 , PMID:22438930 lead(0) affects expression ISO RGD:1606037 6480464 Lead affects the expression of DNMT3B mRNA CTD PMID:28903495 lead(2+) affects expression ISO RGD:1606037 6480464 Lead affects the expression of DNMT3B mRNA CTD PMID:28903495 leflunomide decreases expression ISO RGD:1606037 6480464 leflunomide results in decreased expression of DNMT3B mRNA CTD PMID:28988120 LY294002 multiple interactions ISO RGD:1606037 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Particulate Matter results in increased expression of DNMT3B protein] CTD PMID:26942697 menadione affects expression ISO RGD:1606037 6480464 Vitamin K 3 affects the expression of DNMT3B mRNA CTD PMID:20044591 methoxychlor increases expression EXP 6480464 Methoxychlor results in increased expression of DNMT3B mRNA CTD PMID:19589859 methyl methanesulfonate increases expression ISO RGD:1606037 6480464 Methyl Methanesulfonate results in increased expression of DNMT3B mRNA CTD PMID:23649840 methylmercury chloride decreases expression EXP 6480464 methylmercuric chloride results in decreased expression of DNMT3B mRNA CTD PMID:19636072 microcystin-LR increases expression ISO RGD:1606037 6480464 cyanoginosin LR results in increased expression of DNMT3B mRNA CTD PMID:29518473 Monobutylphthalate decreases expression ISO RGD:1551604 6480464 monobutyl phthalate results in decreased expression of DNMT3B protein CTD PMID:26745512 N-acetyl-L-cysteine multiple interactions ISO RGD:1606037 6480464 Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in decreased expression of DNMT3B protein], Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of DNMT3B protein] CTD PMID:26942697 , PMID:31551408 N-acetyl-L-cysteine multiple interactions ISO RGD:1551604 6480464 Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in decreased expression of DNMT3B protein] CTD PMID:31551408 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO RGD:1551604 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Ethanol results in increased degradation of DNMT3B protein] CTD PMID:23395981 ozone affects response to substance ISO RGD:1606037 6480464 DNMT3B gene polymorphism affects the susceptibility to Ozone CTD PMID:27219456 ozone decreases expression EXP 6480464 Ozone results in decreased expression of DNMT3B mRNA CTD PMID:29947284 p-tert-Amylphenol multiple interactions ISO RGD:1606037 6480464 [4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of DNMT3B mRNA more ... CTD PMID:23626723 paracetamol increases expression ISO RGD:1606037 6480464 Acetaminophen results in increased expression of DNMT3B mRNA CTD PMID:22230336 paracetamol decreases expression ISO RGD:1606037 6480464 Acetaminophen results in decreased expression of DNMT3B mRNA CTD PMID:29665328 pelargonidin decreases expression ISO RGD:1551604 6480464 pelargonidin results in decreased expression of DNMT3B protein CTD PMID:31181187 perfluorooctane-1-sulfonic acid decreases expression ISO RGD:1551604 6480464 perfluorooctane sulfonic acid results in decreased expression of DNMT3B protein CTD PMID:26178269 perfluorooctane-1-sulfonic acid decreases expression ISO RGD:1606037 6480464 perfluorooctane sulfonic acid results in decreased expression of DNMT3B mRNA, perfluorooctane sulfonic acid results in decreased expression of DNMT3B protein CTD PMID:31508952 perfluorooctanoic acid multiple interactions ISO RGD:1551604 6480464 [Dexamethasone co-treated with INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with perfluorooctanoic acid] results in increased expression of DNMT3B mRNA CTD PMID:29094436 perfluorooctanoic acid increases expression ISO RGD:1551604 6480464 perfluorooctanoic acid results in increased expression of DNMT3B mRNA CTD PMID:32320774 perfluorooctanoic acid decreases expression ISO RGD:1606037 6480464 perfluorooctanoic acid results in decreased expression of DNMT3B mRNA CTD PMID:32068100 phenobarbital decreases expression ISO RGD:1551604 6480464 Phenobarbital results in decreased expression of DNMT3B mRNA CTD PMID:19270015 phenobarbital decreases expression EXP 6480464 Phenobarbital results in decreased expression of DNMT3B mRNA CTD PMID:28495587 phenobarbital affects expression ISO RGD:1551604 6480464 Phenobarbital affects the expression of DNMT3B mRNA CTD PMID:23091169 phenylmercury acetate decreases expression ISO RGD:1606037 6480464 Phenylmercuric Acetate results in decreased expression of DNMT3B mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO RGD:1606037 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of DNMT3B mRNA CTD PMID:27188386 pirinixic acid decreases expression ISO RGD:1551604 6480464 pirinixic acid results in decreased expression of DNMT3B mRNA CTD PMID:20813756 potassium chromate multiple interactions ISO RGD:1606037 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of DNMT3B mRNA CTD PMID:22079256 potassium chromate decreases expression ISO RGD:1606037 6480464 potassium chromate(VI) results in decreased expression of DNMT3B mRNA CTD PMID:22079256 procyanidin B2 increases expression ISO RGD:1606037 6480464 procyanidin B2 results in increased expression of DNMT3B mRNA CTD PMID:25839702 pterostilbene multiple interactions ISO RGD:1606037 6480464 pterostilbene promotes the reaction [resveratrol results in decreased expression of DNMT3B mRNA] CTD PMID:26459286 quartz decreases expression ISO RGD:1606037 6480464 Quartz results in decreased expression of DNMT3B mRNA CTD PMID:27917503 quinoline decreases activity ISO RGD:1551604 6480464 quinoline analog results in decreased activity of DNMT3B protein CTD PMID:19417133 resveratrol multiple interactions ISO RGD:1606037 6480464 pterostilbene promotes the reaction [resveratrol results in decreased expression of DNMT3B mRNA], resveratrol inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [DNMT3B protein binds to BRCA1 promoter]] CTD PMID:22197621 , PMID:26459286 resveratrol affects expression EXP 6480464 resveratrol affects the expression of DNMT3B mRNA CTD PMID:24447120 resveratrol increases expression ISO RGD:1606037 6480464 resveratrol results in increased expression of DNMT3B mRNA CTD PMID:26934322 resveratrol decreases expression ISO RGD:1606037 6480464 resveratrol results in decreased expression of DNMT3B mRNA CTD PMID:23593078 , PMID:26459286 SB 431542 multiple interactions ISO RGD:1606037 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 sodium arsenite decreases expression ISO RGD:1606037 6480464 sodium arsenite results in decreased expression of DNMT3B mRNA CTD PMID:19615344 sodium arsenite increases expression ISO RGD:1606037 6480464 sodium arsenite results in increased expression of DNMT3B mRNA, sodium arsenite results in increased expression of DNMT3B protein CTD PMID:24570342 , PMID:30191986 sodium arsenite multiple interactions ISO RGD:1606037 6480464 monoisoamyl-2, 3-dimercaptosuccinate inhibits the reaction [sodium arsenite results in decreased expression of DNMT3B mRNA] CTD PMID:19615344 streptozocin multiple interactions ISO RGD:1551604 6480464 [Streptozocin co-treated with Dietary Fats] results in increased expression of DNMT3B mRNA, [Streptozocin co-treated with Dietary Fats] results in increased expression of DNMT3B protein CTD PMID:29127188 sulforaphane decreases expression ISO RGD:1606037 6480464 sulforafan results in decreased expression of DNMT3B mRNA CTD PMID:24466240 sulforaphane multiple interactions ISO RGD:1606037 6480464 sulforafan inhibits the reaction [DNMT3B protein binds to COMT promoter] more ... CTD PMID:30684530 tamoxifen decreases expression ISO RGD:1551604 6480464 Tamoxifen results in decreased expression of DNMT3B mRNA CTD PMID:25123088 tamoxifen increases expression ISO RGD:1606037 6480464 Tamoxifen results in increased expression of DNMT3B mRNA alternative form, Tamoxifen results in increased expression of DNMT3B protein alternative form CTD PMID:19019622 tamoxifen multiple interactions ISO RGD:1606037 6480464 DNMT3B protein affects the reaction [Tamoxifen results in decreased expression of CXCR4 mRNA], DNMT3B protein affects the reaction [Tamoxifen results in decreased expression of CXCR4 protein] CTD PMID:19019622 testosterone multiple interactions ISO RGD:1606037 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of DNMT3B mRNA CTD PMID:21592394 testosterone multiple interactions EXP 6480464 [Testosterone co-treated with Estradiol] affects the reaction [bisphenol A results in increased expression of DNMT3B mRNA] more ... CTD PMID:20056826 , PMID:22109888 testosterone decreases expression ISO RGD:1606037 6480464 Testosterone results in decreased expression of DNMT3B mRNA CTD PMID:21592394 tetrachloromethane multiple interactions ISO RGD:1551604 6480464 [Carbon Tetrachloride co-treated with Ethanol] results in decreased expression of DNMT3B mRNA CTD PMID:30517762 tetrachloromethane increases expression ISO RGD:1551604 6480464 Carbon Tetrachloride results in increased expression of DNMT3B mRNA CTD PMID:31919559 tributylstannane decreases expression ISO RGD:1551604 6480464 tributyltin results in decreased expression of DNMT3B mRNA CTD PMID:31939706 trichloroethene decreases expression ISO RGD:1551604 6480464 Trichloroethylene results in decreased expression of DNMT3B mRNA CTD PMID:28013219 trichostatin A affects expression ISO RGD:1606037 6480464 [trichostatin A affects the expression of DNMT3B protein] which affects the expression of CDKN1A mRNA more ... CTD PMID:18544619 trichostatin A multiple interactions ISO RGD:1606037 6480464 trichostatin A affects the reaction [hydroquinone affects the expression of DNMT3B mRNA] CTD PMID:31899212 uranium atom increases expression EXP 6480464 Uranium results in increased expression of DNMT3B mRNA CTD PMID:29024790 valproic acid decreases expression ISO RGD:1551604 6480464 Valproic Acid results in decreased expression of DNMT3B mRNA CTD PMID:21427059 valproic acid affects expression ISO RGD:1551604 6480464 Valproic Acid affects the expression of DNMT3B mRNA CTD PMID:26072468 valproic acid affects expression ISO RGD:1606037 6480464 Valproic Acid affects the expression of DNMT3B mRNA CTD PMID:25979313 , PMID:26072468 vanillin decreases expression ISO RGD:1606037 6480464 vanillin results in decreased expression of DNMT3B mRNA CTD PMID:17178418 vinclozolin multiple interactions EXP 6480464 [Testosterone co-treated with vinclozolin] results in increased expression of DNMT3B mRNA, [Testosterone co-treated with vinclozolin] results in increased expression of DNMT3B protein CTD PMID:20056826 vinclozolin increases expression EXP 6480464 vinclozolin results in increased expression of DNMT3B mRNA, vinclozolin results in increased expression of DNMT3B protein CTD PMID:20056826 vinyl carbamate decreases expression ISO RGD:1551604 6480464 vinyl carbamate results in decreased expression of DNMT3B mRNA CTD PMID:17849452 withaferin A decreases expression ISO RGD:1606037 6480464 withaferin A results in decreased expression of DNMT3B mRNA CTD PMID:23593078 wortmannin multiple interactions ISO RGD:1606037 6480464 wortmannin inhibits the reaction [[4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of DNMT3B protein] CTD PMID:23626723
Gene-Chemical Interaction Annotations
