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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:(+)-lariciresinol
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Accession:CHEBI:67246 term browser browse the term
Definition:A lignan that is tetrahydrofuran substituted at positions 2, 3 and 4 by 4-hydroxy-3-methoxyphenyl, hydroxymethyl and 4-hydroxy-3-methoxybenzyl groups respectively (the 2S,3R,4R-diastereomer).
Synonyms:exact_synonym: 4-[(2S,3R,4R)-4-(4-hydroxy-3-methoxybenzyl)-3-(hydroxymethyl)tetrahydrofuran-2-yl]-2-methoxyphenol
 related_synonym: Formula=C20H24O6;   InChI=1S/C20H24O6/c1-24-18-8-12(3-5-16(18)22)7-14-11-26-20(15(14)10-21)13-4-6-17(23)19(9-13)25-2/h3-6,8-9,14-15,20-23H,7,10-11H2,1-2H3/t14-,15-,20+/m0/s1;   InChIKey=MHXCIKYXNYCMHY-AUSJPIAWSA-N;   SMILES=COc1cc(C[C@H]2CO[C@@H]([C@H]2CO)c2ccc(O)c(OC)c2)ccc1O
 xref: CAS:27003-73-2;   CAS:83327-19-9;   KEGG:C10646;   KNApSAcK:C00000602
 xref_mesh: MESH:C060282
 xref: MetaCyc:CPD-8907;   PMID:21138310;   PMID:21679690;   PMID:21973054;   PMID:22218086;   PMID:8262939;   Wikipedia:Lariciresinol
 cyclic_relationship: is_enantiomer_of CHEBI:67244


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(+)-lariciresinol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa1 annexin A1 increases expression ISO lariciresinol results in increased expression of ANXA1 protein CTD PMID:27417256 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343 		JBrowse link
G Basp1 brain abundant, membrane attached signal protein 1 decreases expression ISO lariciresinol results in decreased expression of BASP1 protein CTD PMID:27417256 NCBI chr 2:75,816,130...75,863,801
Ensembl chr 2:75,816,122...75,864,043 		JBrowse link
G Gale UDP-galactose-4-epimerase increases expression ISO lariciresinol results in increased expression of GALE protein CTD PMID:27417256 NCBI chr 5:148,193,886...148,198,392
Ensembl chr 5:148,194,791...148,198,388 		JBrowse link
G Gapdhs glyceraldehyde-3-phosphate dehydrogenase, spermatogenic increases expression ISO lariciresinol results in increased expression of GAPDHS protein CTD PMID:27417256 NCBI chr 1:85,979,096...85,994,153
Ensembl chr 1:85,979,098...85,993,640 		JBrowse link
G Hp haptoglobin decreases expression ISO lariciresinol results in decreased expression of HP protein CTD PMID:27417256 NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 decreases expression ISO lariciresinol results in decreased expression of HSPB1 protein CTD PMID:27417256 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743 		JBrowse link
G Tmod2 tropomodulin 2 decreases expression ISO lariciresinol results in decreased expression of TMOD2 protein CTD PMID:27417256 NCBI chr 8:76,316,736...76,366,003
Ensembl chr 8:76,325,667...76,365,720 		JBrowse link
G Tuba1a tubulin, alpha 1A decreases expression ISO lariciresinol results in decreased expression of TUBA1A protein CTD PMID:27417256 NCBI chr 7:130,113,214...130,116,880
Ensembl chr 7:130,081,032...130,196,186 		JBrowse link
G Ubc ubiquitin C increases expression ISO lariciresinol results in increased expression of UBC protein CTD PMID:27417256 NCBI chr12:31,239,149...31,243,924
Ensembl chr12:31,239,152...31,243,925 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19915
    role 19885
      biological role 19883
        antimicrobial agent 18267
          antifungal agent 17160
            (+)-lariciresinol 9
              (+)-(7S,8R,8'R)-5,5'-dimethoxylariciresinol 0
              (+)-5'-methoxylariciresinol 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19915
    subatomic particle 19913
      composite particle 19895
        hadron 19895
          baryon 19913
            nucleon 19895
              atomic nucleus 19913
                atom 19895
                  main group element atom 19852
                    p-block element atom 19834
                      carbon group element atom 19774
                        carbon atom 19770
                          organic molecular entity 19770
                            organic molecule 19722
                              organic cyclic compound 19529
                                organic aromatic compound 19374
                                  phenylpropanoid 11297
                                    lignan 1706
                                      (+)-lariciresinol 9
                                        (+)-(7S,8R,8'R)-5,5'-dimethoxylariciresinol 0
                                        (+)-5'-methoxylariciresinol 0
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