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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:(+)-lariciresinol
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Accession:CHEBI:67246 term browser browse the term
Definition:A lignan that is tetrahydrofuran substituted at positions 2, 3 and 4 by 4-hydroxy-3-methoxyphenyl, hydroxymethyl and 4-hydroxy-3-methoxybenzyl groups respectively (the 2S,3R,4R-diastereomer).
Synonyms:exact_synonym: 4-[(2S,3R,4R)-4-(4-hydroxy-3-methoxybenzyl)-3-(hydroxymethyl)tetrahydrofuran-2-yl]-2-methoxyphenol
 related_synonym: Formula=C20H24O6;   InChI=1S/C20H24O6/c1-24-18-8-12(3-5-16(18)22)7-14-11-26-20(15(14)10-21)13-4-6-17(23)19(9-13)25-2/h3-6,8-9,14-15,20-23H,7,10-11H2,1-2H3/t14-,15-,20+/m0/s1;   InChIKey=MHXCIKYXNYCMHY-AUSJPIAWSA-N;   SMILES=COc1cc(C[C@H]2CO[C@@H]([C@H]2CO)c2ccc(O)c(OC)c2)ccc1O
 xref: CAS:27003-73-2;   CAS:83327-19-9;   KEGG:C10646;   KNApSAcK:C00000602
 xref_mesh: MESH:C060282
 xref: MetaCyc:CPD-8907;   PMID:21138310;   PMID:21679690;   PMID:21973054;   PMID:22218086;   PMID:8262939;   Wikipedia:Lariciresinol
 cyclic_relationship: is_enantiomer_of CHEBI:67244



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(+)-lariciresinol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa1 annexin A1 increases expression ISO lariciresinol results in increased expression of ANXA1 protein CTD PMID:27417256 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
JBrowse link
G Basp1 brain abundant, membrane attached signal protein 1 decreases expression ISO lariciresinol results in decreased expression of BASP1 protein CTD PMID:27417256 NCBI chr 2:75,816,130...75,863,801
Ensembl chr 2:75,816,122...75,864,043
JBrowse link
G Gale UDP-galactose-4-epimerase increases expression ISO lariciresinol results in increased expression of GALE protein CTD PMID:27417256 NCBI chr 5:148,193,886...148,198,392
Ensembl chr 5:148,194,791...148,198,388
JBrowse link
G Gapdhs glyceraldehyde-3-phosphate dehydrogenase, spermatogenic increases expression ISO lariciresinol results in increased expression of GAPDHS protein CTD PMID:27417256 NCBI chr 1:85,979,096...85,994,153
Ensembl chr 1:85,979,098...85,993,640
JBrowse link
G Hp haptoglobin decreases expression ISO lariciresinol results in decreased expression of HP protein CTD PMID:27417256 NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 decreases expression ISO lariciresinol results in decreased expression of HSPB1 protein CTD PMID:27417256 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
JBrowse link
G Tmod2 tropomodulin 2 decreases expression ISO lariciresinol results in decreased expression of TMOD2 protein CTD PMID:27417256 NCBI chr 8:76,316,736...76,366,003
Ensembl chr 8:76,325,667...76,365,720
JBrowse link
G Tuba1a tubulin, alpha 1A decreases expression ISO lariciresinol results in decreased expression of TUBA1A protein CTD PMID:27417256 NCBI chr 7:130,113,214...130,116,880
Ensembl chr 7:130,081,032...130,196,186
JBrowse link
G Ubc ubiquitin C increases expression ISO lariciresinol results in increased expression of UBC protein CTD PMID:27417256 NCBI chr12:31,239,149...31,243,924
Ensembl chr12:31,239,152...31,243,925
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19918
    role 19894
      biological role 19892
        antimicrobial agent 18166
          antifungal agent 16885
            (+)-lariciresinol 9
              (+)-(7S,8R,8'R)-5,5'-dimethoxylariciresinol 0
              (+)-5'-methoxylariciresinol 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19918
    subatomic particle 19916
      composite particle 19916
        hadron 19916
          baryon 19916
            nucleon 19916
              atomic nucleus 19916
                atom 19916
                  main group element atom 19866
                    p-block element atom 19866
                      carbon group element atom 19811
                        carbon atom 19806
                          organic molecular entity 19806
                            organic molecule 19758
                              organic cyclic compound 19565
                                organic aromatic compound 19430
                                  phenylpropanoid 11114
                                    lignan 1704
                                      (+)-lariciresinol 9
                                        (+)-(7S,8R,8'R)-5,5'-dimethoxylariciresinol 0
                                        (+)-5'-methoxylariciresinol 0
paths to the root