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Gene: S1pr3 (sphingosine-1-phosphate receptor 3) Rattus norvegicus
Symbol: S1pr3
Name: sphingosine-1-phosphate receptor 3
RGD ID: 1583843
Description: Predicted to have G protein-coupled receptor activity and integrin binding activity. Predicted to be involved in several processes, including adenylate cyclase-modulating G protein-coupled receptor signaling pathway; negative regulation of establishment of endothelial barrier; and regulation of interleukin-1 beta production. Predicted to localize to cytoplasm and plasma membrane. Orthologous to human S1PR3 (sphingosine-1-phosphate receptor 3); PARTICIPATES IN sphingosine 1-phosphate signaling pathway; INTERACTS WITH acetamide; aldehydo-D-glucose; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: cardiac sphingosine-1-phosphate specific receptor; Edg3; Edg3l; endothelial differentiation, sphingolipid G-protein-coupled receptor, 3; LOC306792; lpb3; similar to Sphingosine 1-phosphate receptor Edg-3 (S1P receptor Edg-3) (Endothelial differentiation G-protein coupled receptor 3) (Sphingosine 1-phosphate receptor 3) (S1P3) (Lysophospholipid receptor B3); sphingosine 1-phosphate receptor 3
Homo sapiens (human) : S1PR3 (sphingosine-1-phosphate receptor 3)  HGNC  Alliance
Mus musculus (house mouse) : S1pr3 (sphingosine-1-phosphate receptor 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : S1pr3 (sphingosine-1-phosphate receptor 3)
Pan paniscus (bonobo/pygmy chimpanzee) : S1PR3 (sphingosine-1-phosphate receptor 3)
Canis lupus familiaris (dog) : S1PR3 (sphingosine-1-phosphate receptor 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : S1pr3 (sphingosine-1-phosphate receptor 3)
Sus scrofa (pig) : S1PR3 (sphingosine-1-phosphate receptor 3)
Chlorocebus sabaeus (African green monkey) : S1PR3 (sphingosine-1-phosphate receptor 3)
Heterocephalus glaber (naked mole-rat) : S1pr3 (sphingosine-1-phosphate receptor 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01713,799,383 - 13,812,877 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1713,799,383 - 13,812,704 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01715,871,251 - 15,884,751 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41719,657,822 - 19,661,106 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1713,529,246 - 13,542,351 (-)NCBICelera
Cytogenetic Map17p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on S1pr3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1583843
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.