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Gene: S1pr3 (sphingosine-1-phosphate receptor 3) Rattus norvegicus
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Symbol: S1pr3
Name: sphingosine-1-phosphate receptor 3
Description: Predicted to have integrin binding activity. Predicted to be involved in several processes, including Notch signaling pathway; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; and negative regulation of establishment of endothelial barrier. Predicted to localize to the plasma membrane. Orthologous to human S1PR3 (sphingosine-1-phosphate receptor 3); PARTICIPATES IN sphingosine 1-phosphate signaling pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; aldehydo-D-glucose; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: cardiac sphingosine-1-phosphate specific receptor; Edg3; Edg3l; endothelial differentiation, sphingolipid G-protein-coupled receptor, 3; LOC306792; lpb3; similar to Sphingosine 1-phosphate receptor Edg-3 (S1P receptor Edg-3) (Endothelial differentiation G-protein coupled receptor 3) (Sphingosine 1-phosphate receptor 3) (S1P3) (Lysophospholipid receptor B3); sphingosine 1-phosphate receptor 3
Orthologs:
Homo sapiens (human) : S1PR3 (sphingosine-1-phosphate receptor 3)  HGNC  Alliance
Mus musculus (house mouse) : S1pr3 (sphingosine-1-phosphate receptor 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : S1pr3 (sphingosine-1-phosphate receptor 3)
Pan paniscus (bonobo/pygmy chimpanzee) : S1PR3 (sphingosine-1-phosphate receptor 3)
Canis lupus familiaris (dog) : S1PR3 (sphingosine-1-phosphate receptor 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : S1pr3 (sphingosine-1-phosphate receptor 3)
Sus scrofa (pig) : S1PR3 (sphingosine-1-phosphate receptor 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01713,799,383 - 13,812,877 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01715,871,251 - 15,884,751 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41719,657,822 - 19,661,106 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1713,529,246 - 13,542,351 (-)NCBICelera
Cytogenetic Map17p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on S1pr3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1583843
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.