Tufm (Tu translation elongation factor, mitochondrial) - Rat Genome Database

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Gene: Tufm (Tu translation elongation factor, mitochondrial) Rattus norvegicus
Analyze
Symbol: Tufm
Name: Tu translation elongation factor, mitochondrial
RGD ID: 1305501
Description: Predicted to enable translation elongation factor activity. Involved in response to ethanol. Is active in synapse. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 4. Orthologous to human TUFM (Tu translation elongation factor, mitochondrial); INTERACTS WITH 17beta-estradiol; 2,4-dibromophenyl 2,4,5-tribromophenyl ether; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: elongation factor Tu, mitochondrial; LOC293481
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81190,504,373 - 190,507,980 (+)NCBIGRCr8
mRatBN7.21181,073,788 - 181,077,395 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1181,073,788 - 181,077,395 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1189,404,383 - 189,407,991 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01196,590,469 - 196,594,077 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01189,278,338 - 189,281,945 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01197,903,582 - 197,907,189 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1197,903,582 - 197,907,189 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01204,882,342 - 204,885,949 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41185,631,333 - 185,634,940 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11185,780,653 - 185,784,699 (+)NCBI
Celera1178,732,489 - 178,736,096 (+)NCBICelera
Cytogenetic Map1q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
(Z)-3-butylidenephthalide  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP)
2-amino-14,16-dimethyloctadecan-3-ol  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-chloropropane-1,2-diol  (EXP)
4,4'-sulfonyldiphenol  (ISO)
actinomycin D  (ISO)
all-trans-retinoic acid  (ISO)
artesunate  (ISO)
aspartame  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
Brodifacoum  (EXP)
buspirone  (EXP)
butan-1-ol  (ISO)
cadmium dichloride  (EXP)
carbon nanotube  (ISO)
carmustine  (ISO)
clofibrate  (EXP)
clofibric acid  (EXP)
cyclosporin A  (ISO)
Dibutyl phosphate  (ISO)
Diisodecyl phthalate  (ISO)
disodium selenite  (ISO)
dopamine  (ISO)
doxorubicin  (EXP,ISO)
enzyme inhibitor  (ISO)
ethanol  (ISO)
etoposide  (ISO)
fenvalerate  (EXP)
flutamide  (EXP)
gentamycin  (EXP)
glyphosate  (ISO)
gold atom  (ISO)
gold(0)  (ISO)
hexadecanoic acid  (ISO)
ivermectin  (ISO)
lipopolysaccharide  (ISO)
lovastatin  (ISO)
methamphetamine  (EXP)
microcystin-LR  (EXP)
monosodium L-glutamate  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (EXP)
Nonylphenol  (EXP)
Nutlin-3  (ISO)
oleic acid  (ISO)
ozone  (EXP)
paracetamol  (ISO)
paraoxon  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
Propiverine  (EXP)
quercetin  (ISO)
resveratrol  (ISO)
rotenone  (EXP)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
Soman  (EXP)
sunitinib  (ISO)
T-2 toxin  (EXP)
temozolomide  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
triptonide  (ISO)
valproic acid  (ISO)
warfarin  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
mitochondrial nucleoid  (ISO)
mitochondrion  (IBA,ISO)
synapse  (EXP,IDA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Proteomics analysis of rat brain postsynaptic density. Implications of the diverse protein functional groups for the integration of synaptic physiology. Li KW, etal., J Biol Chem. 2004 Jan 9;279(2):987-1002. doi: 10.1074/jbc.M303116200. Epub 2003 Oct 7.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Chronic ethanol feeding causes depression of mitochondrial elongation factor Tu in the rat liver: implications for the mitochondrial ribosome. Weiser B, etal., Am J Physiol Gastrointest Liver Physiol. 2011 May;300(5):G815-22. doi: 10.1152/ajpgi.00108.2010. Epub 2011 Feb 24.
Additional References at PubMed
PMID:9332382   PMID:12865426   PMID:14651853   PMID:17634366   PMID:18063578   PMID:18614015   PMID:19946888   PMID:20458337   PMID:20833797   PMID:21700703   PMID:22658674   PMID:23041468  
PMID:24625528   PMID:25002582   PMID:29476059   PMID:30053369   PMID:30361391   PMID:32357304   PMID:35352799  


Genomics

Comparative Map Data
Tufm
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81190,504,373 - 190,507,980 (+)NCBIGRCr8
mRatBN7.21181,073,788 - 181,077,395 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1181,073,788 - 181,077,395 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1189,404,383 - 189,407,991 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01196,590,469 - 196,594,077 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01189,278,338 - 189,281,945 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01197,903,582 - 197,907,189 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1197,903,582 - 197,907,189 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01204,882,342 - 204,885,949 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41185,631,333 - 185,634,940 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11185,780,653 - 185,784,699 (+)NCBI
Celera1178,732,489 - 178,736,096 (+)NCBICelera
Cytogenetic Map1q36NCBI
TUFM
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381628,842,411 - 28,846,348 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1628,842,411 - 28,846,348 (-)EnsemblGRCh38hg38GRCh38
GRCh371628,853,732 - 28,857,669 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361628,761,613 - 28,765,144 (-)NCBINCBI36Build 36hg18NCBI36
Build 341628,761,613 - 28,765,144NCBI
Celera1627,808,340 - 27,812,337 (-)NCBICelera
Cytogenetic Map16p11.2NCBI
HuRef1626,721,293 - 26,725,288 (-)NCBIHuRef
CHM1_11629,865,576 - 29,869,573 (-)NCBICHM1_1
T2T-CHM13v2.01629,122,980 - 29,140,210 (-)NCBIT2T-CHM13v2.0
Tufm
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397126,086,445 - 126,089,903 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7126,086,533 - 126,089,903 (+)EnsemblGRCm39 Ensembl
GRCm387126,487,271 - 126,490,731 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7126,487,361 - 126,490,731 (+)EnsemblGRCm38mm10GRCm38
MGSCv377133,630,869 - 133,634,245 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367126,278,580 - 126,281,878 (+)NCBIMGSCv36mm8
Celera7126,339,931 - 126,343,307 (+)NCBICelera
Cytogenetic Map7F3NCBI
cM Map769.08NCBI
Tufm
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554936,619,205 - 6,623,780 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554936,619,205 - 6,623,780 (+)NCBIChiLan1.0ChiLan1.0
TUFM
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21831,899,627 - 31,917,744 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11636,731,726 - 36,735,282 (+)NCBINHGRI_mPanPan1
PanPan1.11629,229,905 - 29,233,508 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1629,227,852 - 29,233,513 (-)Ensemblpanpan1.1panPan2
TUFM
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1618,357,223 - 18,360,929 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl618,357,244 - 18,361,557 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha619,935,471 - 19,939,110 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0618,493,014 - 18,496,651 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl618,493,018 - 18,496,775 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1618,292,398 - 18,296,035 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0618,207,329 - 18,210,966 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0618,523,444 - 18,527,083 (-)NCBIUU_Cfam_GSD_1.0
Tufm
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344123,761,676 - 123,765,829 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650111,859,552 - 11,865,747 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650111,859,558 - 11,863,689 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TUFM
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl318,521,128 - 18,524,959 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1318,521,119 - 18,524,705 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2318,706,416 - 18,709,827 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TUFM
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1526,221,203 - 26,225,080 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl526,221,337 - 26,225,083 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660683,348,805 - 3,353,298 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tufm
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478212,914,359 - 12,918,194 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478212,914,362 - 12,918,194 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tufm
7 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:31
Count of miRNA genes:30
Interacting mature miRNAs:31
Transcripts:ENSRNOT00000025203
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1150700247252085048Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512256448636Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
1354652Kidm20Kidney mass QTL 204.3kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1177227632256448636Rat
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1144267353251128347Rat
1354653Despr9Despair related QTL 90.00019locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1167909849212909849Rat
1578770Stresp23Stress response QTL 23kidney sympathetic nerve activity (VT:0004050)stimulated renal sympathetic nerve activity to basal renal sympathetic nerve activity ratio (CMO:0001786)1123350408182418476Rat
2293673Bss27Bone structure and strength QTL 2718.630.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)1171629477216629477Rat
61326Eae6Experimental allergic encephalomyelitis QTL 65.3body mass (VT:0001259)change in body weight (CMO:0002045)1172949660181830018Rat
2293677Bss41Bone structure and strength QTL 419.380.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)1171629477216629477Rat
1302787Stl25Serum triglyceride level QTL 252.70.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)1180359209210702199Rat
70160Bw18Body weight QTL 185.7body mass (VT:0001259)body weight (CMO:0000012)1144267353196383668Rat
1549830Bss1Bone structure and strength QTL 14.8femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)1172609619217609619Rat
7794788Mcs32Mammary carcinoma susceptibility QTL 322.61mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)1115540693238914717Rat
70163Bw20Body weight QTL 205.1body mass (VT:0001259)body weight (CMO:0000012)1174133260219133260Rat
1578763Kidm29Kidney mass QTL 293.30.0001kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1179567751260522016Rat
1354624Cm35Cardiac mass QTL355.7heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1177227632256448636Rat
1558658Bw59Body weight QTL 593.50.0003body mass (VT:0001259)body weight (CMO:0000012)1178784622223784622Rat
1354636Lmblg1Limb length QTL 16.4tibia length (VT:0004357)tibia length (CMO:0000450)1151162512201278233Rat
1549837Hcar15Hepatocarcinoma resistance QTL 150.05liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1153136852260522016Rat
2293689Bss47Bone structure and strength QTL 477.250.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)1171629477216629477Rat
1598853Memor3Memory QTL 34.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)1143506580212458660Rat
61341Bp26Blood pressure QTL 26arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1169537671214537671Rat
1354634Kidm12Kidney mass QTL 123.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)1151162512201278233Rat
4889428Stresp24Stress response QTL 240.05heart pumping trait (VT:2000009)absolute change in electrocardiographic low frequency R-R spectral component to high frequency R-R spectral component ratio (CMO:0002162)1155866514200866514Rat
1578759Uae30Urinary albumin excretion QTL 303.30.003urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1150700247252085048Rat
61343Bp28Blood pressure QTL 28arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1151646613196646613Rat
2293693Bss22Bone structure and strength QTL 2233.520.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1171629477216629477Rat
2300161Bmd43Bone mineral density QTL 438.40.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1171629477216629477Rat
61347Bp197Blood pressure QTL 1974.2arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)1158633083203633083Rat
61348Bp30Blood pressure QTL 302.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1144017057197814409Rat
8655649Arrd1Age-related retinal degeneration QTL 14.89retinal layer morphology trait (VT:0003727)percentage of study population developing retinopathy during a period of time (CMO:0002453)1100357752183970443Rat
2303622Vencon6Ventilatory control QTL 60.001respiration trait (VT:0001943)respiration rate (CMO:0000289)1154561505199561505Rat
631214Bw61Body weight QTL613.40.0001intramuscular adipose amount (VT:0010044)intramuscular fat area (CMO:0001162)1173108781218108781Rat
7771612Cm80Cardiac mass QTL 808.4heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)1149448574221264292Rat
731168Bp154Blood pressure QTL 1543.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194642644214537671Rat
631205Bp196Blood pressure QTL 19640.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1118944897199050459Rat
1300158Bp173Blood pressure QTL 1733.48arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)1115540693185145286Rat
2300174Bmd42Bone mineral density QTL 428.40.0001lumbar vertebra mineral mass (VT:0010511)bone mineral density (CMO:0001226)1171629477216629477Rat
737828Hcas3Hepatocarcinoma susceptibility QTL 34.9liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)1144267353222987745Rat
1331749Hrtrt11Heart rate QTL 112.973heart pumping trait (VT:2000009)heart rate (CMO:0000002)194494440198211706Rat
1354661Bw33Body weight QTL 335.2body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
1358886Bp260Blood pressure QTL 2603.67arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1151162766225824951Rat
1331751Bp199Blood pressure QTL 1993.60022arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)194494440181830018Rat
2293654Bss30Bone structure and strength QTL 3032.650.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1171629477216629477Rat
724531Uae5Urinary albumin excretion QTL 54urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)1150700142252085212Rat
2300187Bmd41Bone mineral density QTL 418.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1171629477216629477Rat
737974Bp161Blood pressure QTL 1610.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1164747558181133855Rat
1641895Bp298Blood pressure QTL 298arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1123350408182418476Rat
70209Niddm23Non-insulin dependent diabetes mellitus QTL 232.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)194494440198324465Rat
1354580Scort1Serum corticosterone level QTL 13.4blood corticosterone amount (VT:0005345)blood corticosterone level (CMO:0001172)1156677124256448636Rat
1358294Bw37Body weight QTL 3750.000011body mass (VT:0001259)body weight (CMO:0000012)1171310381216310381Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
2312420Pur17Proteinuria QTL 177.10.0001urine protein amount (VT:0005160)urine total protein excretion rate (CMO:0000756)1156677124218753816Rat
10059600Bp378Blood pressure QTL 3783.080.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1176869060221869060Rat
1354591Cm36Cardiac mass QTL 364.1heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1102813953201278233Rat
724550Thym3Thymus enlargement QTL 37.820.001thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)1136829932181829932Rat
2312558Glom17Glomerulus QTL 173.90.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)1166532971191278129Rat
7421630Bp362Blood pressure QTL 3620.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1118608292241799120Rat
71118Thym1Thymus enlargement QTL 110.170.001thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)1136829932181829932Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
619613Bp77Blood pressure QTL 770.01arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1164747424209747424Rat
631519Pia11Pristane induced arthritis QTL 115.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1136830018181830018Rat
619614Bp78Blood pressure QTL 780.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1169112897197261052Rat
634321Hc1Hypercalciuria QTL 12.91urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1178810256240830002Rat
724562Rends1Renal damage susceptibility QTL 10.05kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)1169537671214537671Rat
2292222Bp307Blood pressure QTL 3073.060.0014arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1164310393213533942Rat
2292220Bp306Blood pressure QTL 3063.470.00087arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1164310393243914901Rat
1354615Cm32Cardiac mass QTL 325.2heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1102813953201278233Rat
1600380Niddm70Non-insulin dependent diabetes mellitus QTL 703.10.0008blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1176550523221550523Rat
1354610Bw34Body weight QTL 344.1body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
1354620Kidm19Kidney mass QTL 194kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512201278233Rat
1354618Kidm15Kidney mass QTL 155kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)1156677124201278233Rat
6903303Scl34Serum cholesterol QTL 342.50.0033blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)1180359209218108781Rat
631544Bp84Blood pressure QTL 845.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1123350408181759564Rat
631549Bp89Blood pressure QTL 895.7arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1123350581201284552Rat
1358189Cstrr1Cold stress response QTL 10.0001catecholamine amount (VT:0010543)urine norepinephrine level (CMO:0001629)1123350408182418476Rat
1354606Bp246Blood pressure QTL 2463.6arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)1102813953218753816Rat
738032Hcas5Hepatocarcinoma susceptibility QTL 53.12liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1176426412257976495Rat
1354602Bw35Body weight QTL 3512.2body mass (VT:0001259)body weight (CMO:0000012)1151162512201278233Rat
2325725Eae31Experimental allergic encephalomyelitis QTL 31nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)1178810256188377506Rat
631670Iddm10Insulin dependent diabetes mellitus QTL 101.9blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1174133260196383668Rat

Markers in Region
RH127594  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21181,076,537 - 181,077,179 (+)MAPPERmRatBN7.2
Rnor_6.01197,906,332 - 197,906,973NCBIRnor6.0
Rnor_5.01204,885,092 - 204,885,733UniSTSRnor5.0
RGSC_v3.41185,634,083 - 185,634,724UniSTSRGSC3.4
Celera1178,735,239 - 178,735,880UniSTS
Cytogenetic Map1q36UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000025203   ⟹   ENSRNOP00000025203
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1181,073,788 - 181,077,395 (+)Ensembl
Rnor_6.0 Ensembl1197,903,582 - 197,907,189 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000109633   ⟹   ENSRNOP00000084136
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1181,074,047 - 181,077,348 (+)Ensembl
RefSeq Acc Id: NM_001106295   ⟹   NP_001099765
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81190,504,373 - 190,507,980 (+)NCBI
mRatBN7.21181,073,788 - 181,077,395 (+)NCBI
Rnor_6.01197,903,582 - 197,907,189 (+)NCBI
Rnor_5.01204,882,342 - 204,885,949 (+)NCBI
RGSC_v3.41185,631,333 - 185,634,940 (+)RGD
Celera1178,732,489 - 178,736,096 (+)RGD
Sequence:
RefSeq Acc Id: NP_001099765   ⟸   NM_001106295
- Peptide Label: precursor
- UniProtKB: P85834 (UniProtKB/Swiss-Prot),   A6I973 (UniProtKB/TrEMBL),   A0A8I5ZXD5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000025203   ⟸   ENSRNOT00000025203
Ensembl Acc Id: ENSRNOP00000084136   ⟸   ENSRNOT00000109633
Protein Domains
tr-type G

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P85834-F1-model_v2 AlphaFold P85834 1-452 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13690399
Promoter ID:EPDNEW_R923
Type:initiation region
Name:Tufm_1
Description:Tu translation elongation factor, mitochondrial
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01197,903,846 - 197,903,906EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305501 AgrOrtholog
BioCyc Gene G2FUF-57448 BioCyc
Ensembl Genes ENSRNOG00000018604 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055031153 UniProtKB/Swiss-Prot
  ENSRNOG00060029136 UniProtKB/Swiss-Prot
  ENSRNOG00065016529 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000025203.7 UniProtKB/Swiss-Prot
  ENSRNOT00000109633.1 UniProtKB/TrEMBL
  ENSRNOT00055054012 UniProtKB/Swiss-Prot
  ENSRNOT00060050579 UniProtKB/Swiss-Prot
  ENSRNOT00065027543 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Translation factors UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro EF-Tu_GTP-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF-Tu_GTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EFTu-like_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EFTU_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G_TR_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  T_Tr_GTP-bd_dom UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
  Transl_B-barrel_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Transl_elong_EF1A/Init_IF2_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Transl_elong_EFTu/EF1A_bac/org UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Transl_elong_EFTu/EF1A_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:293481 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 293481 ENTREZGENE
PANTHER ELONGATION FACTOR TU, MITOCHONDRIAL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ELONGATION FACTOR TU-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam GTP_EFTU UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GTP_EFTU_D2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GTP_EFTU_D3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Tufm PhenoGen
PRINTS ELONGATNFCT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE G_TR_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G_TR_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000018604 RatGTEx
  ENSRNOG00055031153 RatGTEx
  ENSRNOG00060029136 RatGTEx
  ENSRNOG00065016529 RatGTEx
Superfamily-SCOP SSF50447 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF50465 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZXD5 ENTREZGENE, UniProtKB/TrEMBL
  A6I973 ENTREZGENE, UniProtKB/TrEMBL
  A6I975_RAT UniProtKB/TrEMBL
  EFTU_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Tufm  Tu translation elongation factor, mitochondrial   Tufm_predicted  Tu translation elongation factor, mitochondrial (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Tufm_predicted  Tu translation elongation factor, mitochondrial (predicted)      Symbol and Name status set to approved 70820 APPROVED