Col5a1 (collagen type V alpha 1 chain) - Rat Genome Database

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Gene: Col5a1 (collagen type V alpha 1 chain) Rattus norvegicus
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Symbol: Col5a1
Name: collagen type V alpha 1 chain
RGD ID: 70920
Description: Enables heparin binding activity. Predicted to be involved in several processes, including collagen biosynthetic process; collagen fibril organization; and wound healing, spreading of epidermal cells. Predicted to act upstream of or within several processes, including circulatory system development; skin development; and tendon development. Predicted to be located in basement membrane. Predicted to be part of collagen type V trimer. Predicted to be active in collagen-containing extracellular matrix and extracellular space. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome and Ehlers-Danlos syndrome classic type 1. Orthologous to human COL5A1 (collagen type V alpha 1 chain); PARTICIPATES IN syndecan signaling pathway; cell-extracellular matrix signaling pathway; Entamoebiasis pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: collagen alpha 1 (V); collagen alpha-1(V) chain; collagen, type V, alpha 1; procollagen, type V, alpha 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8331,606,475 - 31,755,097 (+)NCBIGRCr8
mRatBN7.2311,208,429 - 11,356,715 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl311,208,512 - 11,354,588 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx314,276,142 - 14,421,992 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0322,861,404 - 23,007,143 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0321,115,526 - 21,261,367 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.036,430,180 - 6,581,010 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl36,430,201 - 6,578,882 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0311,788,675 - 11,937,880 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.436,826,169 - 6,971,054 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.136,826,468 - 6,971,354 (+)NCBI
Celera36,002,130 - 6,146,263 (+)NCBICelera
Cytogenetic Map3p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Col5a1RatEhlers-Danlos syndrome  ISORGD:7334351581211 RGD 
Col5a1RatEhlers-Danlos syndrome  ISORGD:7334351581212 RGD 
Col5a1RatEhlers-Danlos syndrome  ISORGD:7334351581210 RGD 
Col5a1RatEhlers-Danlos syndrome  ISORGD:733435734808DNA:repeat:intron:IVS17 (human)RGD 
1 to 20 of 56 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Col5a1Rat17-beta hydroxysteroid dehydrogenase 3 deficiency  ISORGD:7334358554872ClinVar Annotator: match by term: 17 alpha ketosteroid reductase deficiency of testisClinVarPMID:25326637|PMID:25741868|PMID:28492532
Col5a1RatAdams-Oliver Syndrome 5  ISORGD:7334358554872ClinVar Annotator: match by term: Adams-Oliver syndrome 5ClinVarPMID:28492532|PMID:29907982
Col5a1Rataortic aneurysm  ISORGD:7334358554872ClinVar Annotator: match by term: Aortic dilatationClinVarPMID:28492532
Col5a1Rataortic valve disease 1  ISORGD:7334358554872ClinVar Annotator: match by term: Aortic valve disease 1ClinVarPMID:25741868|PMID:28074886|PMID:28492532|PMID:30858776|PMID:31903434|PMID:33737726
Col5a1RatBrugada syndrome  ISORGD:7334358554872ClinVar Annotator: match by term: Brugada syndromeClinVar 
Col5a1RatCardiac Arrhythmias  ISORGD:7334358554872ClinVar Annotator: match by term: Cardiac arrhythmiaClinVarPMID:17576681|PMID:25741868|PMID:28492532|PMID:28914264|PMID:9536098
Col5a1Ratclubfoot  ISORGD:7334358554872ClinVar Annotator: match by term: ClubfootClinVarPMID:25741868
Col5a1RatConfusion  ISORGD:7334358554872ClinVar Annotator: match by term: ConfusionClinVarPMID:25741868|PMID:28492532
Col5a1Ratconnective tissue disease  ISORGD:7334358554872ClinVar Annotator: match by term: Connective tissue disease | ClinVar Annotator: match by term: Connective more ...ClinVarPMID:10602121|PMID:10796876|PMID:10946364|PMID:11992482|PMID:15580559|PMID:17576681|PMID:19370768|PMID:20635400|PMID:20979576|PMID:22696272|PMID:24033266|PMID:25741868|PMID:27975164|PMID:28074886|PMID:28492532|PMID:28550590|PMID:29924831|PMID:30858776|PMID:31903434|PMID:33726816|PMID:33737726|PMID:33914963|PMID:34422331|PMID:36411388|PMID:9536098
Col5a1Ratdevelopmental and epileptic encephalopathy 14  ISORGD:7334358554872ClinVar Annotator: match by term: Developmental and epileptic encephalopathy, 14ClinVarPMID:28492532
Col5a1RatEhlers-Danlos syndrome  ISORGD:7334358554872ClinVar Annotator: match by term: Ehlers-Danlos syndromeClinVarPMID:10471441|PMID:10602121|PMID:10777716|PMID:10946364|PMID:11992482|PMID:12145749|PMID:15580559|PMID:16199547|PMID:16431952|PMID:19370768|PMID:20635400|PMID:20979576|PMID:22696272|PMID:23587214|PMID:24033266|PMID:25122555|PMID:25741868|PMID:26608033|PMID:26854089|PMID:27011056|PMID:28074886|PMID:28485813|PMID:28492532|PMID:28550590|PMID:29924831|PMID:30675029|PMID:30858776|PMID:31064749|PMID:31829210|PMID:32508047|PMID:32938213|PMID:33206719|PMID:33737726|PMID:33914963|PMID:34150014|PMID:34265140|PMID:35128800|PMID:35396906|PMID:35723357|PMID:35982159|PMID:36973604|PMID:37427422
Col5a1RatEhlers-Danlos syndrome arthrochalasia type 1  ISORGD:7334358554872ClinVar Annotator: match by term: Ehlers-Danlos syndrome type 7A | ClinVar Annotator: match by term: more ...ClinVarPMID:10471441|PMID:10602121|PMID:10946364|PMID:11992482|PMID:12145749|PMID:15580559|PMID:17576681|PMID:19019335|PMID:19370768|PMID:20635400|PMID:20979576|PMID:22696272|PMID:24033266|PMID:24685354|PMID:24951259|PMID:25741868|PMID:26608033|PMID:26854089|PMID:27011056|PMID:28492532|PMID:29924831|PMID:30858776|PMID:9536098
Col5a1RatEhlers-Danlos syndrome arthrochalasia type 1  ISORGD:7334358554872ClinVar Annotator: match by term: Ehlers-Danlos syndrome type 7AClinVarPMID:10471441|PMID:10602121|PMID:10946364|PMID:11992482|PMID:12145749|PMID:15580559|PMID:17576681|PMID:19019335|PMID:19370768|PMID:20635400|PMID:20979576|PMID:22696272|PMID:24033266|PMID:24685354|PMID:24951259|PMID:25741868|PMID:26608033|PMID:26854089|PMID:27011056|PMID:28492532|PMID:29924831|PMID:30858776|PMID:32508047|PMID:33737726|PMID:35723357|PMID:9536098
Col5a1RatEhlers-Danlos syndrome arthrochalasia type 1  ISORGD:7334358554872ClinVar Annotator: match by term: Ehlers-Danlos syndrome type 7AClinVarPMID:10471441|PMID:10602121|PMID:10946364|PMID:11992482|PMID:12145749|PMID:15580559|PMID:17576681|PMID:19019335|PMID:19370768|PMID:20635400|PMID:20979576|PMID:22696272|PMID:24033266|PMID:24685354|PMID:24951259|PMID:25741868|PMID:26608033|PMID:26854089|PMID:27011056|PMID:28492532|PMID:29924831|PMID:30858776|PMID:32508047|PMID:9536098
Col5a1RatEhlers-Danlos syndrome arthrochalasia type 1  ISORGD:7334358554872ClinVar Annotator: match by term: Ehlers-Danlos syndrome arthrochalasia type | ClinVar Annotator: match by term: more ...ClinVarPMID:10471441|PMID:10602121|PMID:10946364|PMID:11992482|PMID:12145749|PMID:15580559|PMID:17576681|PMID:19019335|PMID:19370768|PMID:20635400|PMID:20979576|PMID:22696272|PMID:24033266|PMID:24685354|PMID:24951259|PMID:25741868|PMID:26608033|PMID:26854089|PMID:27011056|PMID:28166811|PMID:28492532|PMID:29924831|PMID:30858776|PMID:9536098
Col5a1RatEhlers-Danlos syndrome classic type 1  ISORGD:7334358554872ClinVar Annotator: match by term: EHLERS-DANLOS SYNDROME, GRAVIS TYPE | ClinVar Annotator: match by term: more ...ClinVarPMID:10471441|PMID:10602121|PMID:10777716|PMID:10796876|PMID:10946364|PMID:11992482|PMID:12145749|PMID:15264295|PMID:15580559|PMID:16199547|PMID:16431952|PMID:16751282|PMID:17576681|PMID:18972565|PMID:19011090|PMID:19019335|PMID:19344236|PMID:19370768|PMID:20301422|PMID:20635400|PMID:20979576|PMID:21611149|PMID:22696272|PMID:23587214|PMID:24033266|PMID:24088041|PMID:24685354|PMID:24951259|PMID:25326637|PMID:25640679|PMID:25741868|PMID:26188975|PMID:26608033|PMID:26633545|PMID:26854089|PMID:27011056|PMID:27959697|PMID:27975164|PMID:28454995|PMID:28485813|PMID:28492532|PMID:28550590|PMID:28714197|PMID:28748566|PMID:29578302|PMID:29907982|PMID:29924831|PMID:30467950|PMID:30858776|PMID:31064749|PMID:31141158|PMID:31625567|PMID:31660461|PMID:31903434|PMID:32581362|PMID:32720758|PMID:32766464|PMID:32938213|PMID:33161638|PMID:33206719|PMID:33656776|PMID:33834621|PMID:35723357|PMID:7695699|PMID:8218237|PMID:8575750|PMID:8923000|PMID:8950675|PMID:9042913|PMID:9536098|PMID:9683580
Col5a1RatEhlers-Danlos syndrome classic type 1  ISORGD:7334358554872ClinVar Annotator: match by term: EHLERS-DANLOS SYNDROME, CLASSIC TYPE, 1 | ClinVar Annotator: match by more ...ClinVarPMID:10471441|PMID:10602121|PMID:10777716|PMID:10796876|PMID:10946364|PMID:11992482|PMID:12145749|PMID:15264295|PMID:15580559|PMID:16199547|PMID:16751282|PMID:17576681|PMID:18972565|PMID:19011090|PMID:19019335|PMID:19344236|PMID:19370768|PMID:20301422|PMID:20635400|PMID:20979576|PMID:22696272|PMID:23587214|PMID:24033266|PMID:24088041|PMID:24685354|PMID:24951259|PMID:25326637|PMID:25640679|PMID:25741868|PMID:26608033|PMID:26633545|PMID:26854089|PMID:27011056|PMID:28166811|PMID:28454995|PMID:28492532|PMID:28550590|PMID:29924831|PMID:30858776|PMID:31064749|PMID:31141158|PMID:31903434|PMID:32581362|PMID:32720758|PMID:32938213|PMID:35723357|PMID:7695699|PMID:8218237|PMID:8575750|PMID:8923000|PMID:8950675|PMID:9042913|PMID:9536098|PMID:9683580
Col5a1RatEhlers-Danlos syndrome classic type 1  ISORGD:7334358554872ClinVar Annotator: match by term: EHLERS-DANLOS SYNDROME, SEVERE CLASSIC TYPE | ClinVar Annotator: match by more ...ClinVarPMID:10471441|PMID:10602121|PMID:10777716|PMID:10796876|PMID:10946364|PMID:11992482|PMID:12145749|PMID:15264295|PMID:15580559|PMID:16199547|PMID:16751282|PMID:17576681|PMID:18972565|PMID:19011090|PMID:19019335|PMID:19344236|PMID:19370768|PMID:20301422|PMID:20635400|PMID:20979576|PMID:22696272|PMID:23587214|PMID:24033266|PMID:24088041|PMID:24685354|PMID:24951259|PMID:25640679|PMID:25741868|PMID:26608033|PMID:26633545|PMID:26854089|PMID:27011056|PMID:28166811|PMID:28454995|PMID:28492532|PMID:28550590|PMID:29924831|PMID:30858776|PMID:31064749|PMID:31141158|PMID:31903434|PMID:32581362|PMID:32720758|PMID:32938213|PMID:35723357|PMID:7695699|PMID:8218237|PMID:8575750|PMID:8923000|PMID:8950675|PMID:9042913|PMID:9536098|PMID:9683580
Col5a1RatEhlers-Danlos syndrome classic type 1  ISORGD:7334358554872ClinVar Annotator: match by term: EDS I | ClinVar Annotator: match by term: EHLERS-DANLOS SYNDROME, more ...ClinVarPMID:10471441|PMID:10602121|PMID:10777716|PMID:10796876|PMID:10946364|PMID:11992482|PMID:12145749|PMID:15264295|PMID:15580559|PMID:16199547|PMID:16431952|PMID:16751282|PMID:17576681|PMID:18972565|PMID:19011090|PMID:19019335|PMID:19344236|PMID:19370768|PMID:20301422|PMID:20308875|PMID:20635400|PMID:20979576|PMID:21541907|PMID:21611149|PMID:22696272|PMID:23587214|PMID:24033266|PMID:24088041|PMID:24685354|PMID:24951259|PMID:25122555|PMID:25326637|PMID:25640679|PMID:25741868|PMID:26608033|PMID:26633545|PMID:26854089|PMID:27011056|PMID:27959697|PMID:27975164|PMID:28074886|PMID:28306229|PMID:28454995|PMID:28485813|PMID:28492532|PMID:28550590|PMID:28748566|PMID:28914264|PMID:29578302|PMID:29907982|PMID:29924831|PMID:30467950|PMID:30675029|PMID:30858776|PMID:31061749|PMID:31064749|PMID:31141158|PMID:31239369|PMID:31625567|PMID:31660461|PMID:31829210|PMID:31903434|PMID:32467296|PMID:32508047|PMID:32581362|PMID:32720758|PMID:32736638|PMID:32766464|PMID:32938213|PMID:33161638|PMID:33206719|PMID:33656776|PMID:33726816|PMID:33737726|PMID:33834621|PMID:33914963|PMID:34041919|PMID:34150014|PMID:34265140|PMID:34422331|PMID:35128800|PMID:35234813|PMID:35396906|PMID:35599849|PMID:35723357|PMID:35982159|PMID:36411388|PMID:36973604|PMID:37079061|PMID:37427422|PMID:37884635|PMID:38254962|PMID:38929591|PMID:7695699|PMID:8218237|PMID:8575750|PMID:8923000|PMID:8950675|PMID:9042913|PMID:9536098|PMID:9683580
Col5a1RatEhlers-Danlos syndrome classic type 1  ISORGD:7334358554872ClinVar Annotator: match by term: EHLERS-DANLOS SYNDROME, CLASSIC TYPE, 1 | ClinVar Annotator: match by more ...ClinVarPMID:10471441|PMID:10602121|PMID:10777716|PMID:10796876|PMID:10946364|PMID:11992482|PMID:12145749|PMID:15264295|PMID:15580559|PMID:16199547|PMID:16431952|PMID:16751282|PMID:17576681|PMID:18972565|PMID:19011090|PMID:19019335|PMID:19344236|PMID:19370768|PMID:20301422|PMID:20635400|PMID:20979576|PMID:21611149|PMID:22696272|PMID:23587214|PMID:24033266|PMID:24088041|PMID:24685354|PMID:24951259|PMID:25326637|PMID:25640679|PMID:25741868|PMID:26188975|PMID:26608033|PMID:26633545|PMID:26854089|PMID:27011056|PMID:27959697|PMID:27975164|PMID:28074886|PMID:28454995|PMID:28485813|PMID:28492532|PMID:28550590|PMID:28714197|PMID:28748566|PMID:29578302|PMID:29907982|PMID:29924831|PMID:30467950|PMID:30858776|PMID:31064749|PMID:31141158|PMID:31625567|PMID:31660461|PMID:31903434|PMID:32508047|PMID:32581362|PMID:32720758|PMID:32766464|PMID:32938213|PMID:33161638|PMID:33206719|PMID:33656776|PMID:33834621|PMID:34422331|PMID:35723357|PMID:7695699|PMID:8218237|PMID:8575750|PMID:8923000|PMID:8950675|PMID:9042913|PMID:9536098|PMID:9683580
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1 to 10 of 10 rows
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Original Reference(s)
Col5a1RatAnimal Mammary Neoplasms  ISORGD:73343511554173CTD Direct Evidence: marker/mechanismCTDPMID:12376462
Col5a1Ratcarcinoma  ISORGD:73343511554173CTD Direct Evidence: marker/mechanismCTDPMID:12376462
Col5a1RatEhlers-Danlos syndrome classic type 1  ISORGD:73343511554173CTD Direct Evidence: marker/mechanismCTDPMID:8752669|PMID:9042913|PMID:20635400
Col5a1RatEhlers-Danlos syndrome classic type 2  ISORGD:73343511554173CTD Direct Evidence: marker/mechanismCTDPMID:8752669|PMID:9042913
Col5a1RatExperimental Liver Cirrhosis  ISORGD:73343511554173CTD Direct Evidence: marker/mechanismCTDPMID:25380136
Col5a1RatExperimental Mammary Neoplasms  ISORGD:73343511554173CTD Direct Evidence: marker/mechanismCTDPMID:12376462
Col5a1RatKeloid  ISORGD:73343511554173CTD Direct Evidence: marker/mechanismCTDPMID:20128793
Col5a1RatProstatic Neoplasms  ISORGD:73343511554173CTD Direct Evidence: marker/mechanismCTDPMID:29610475
Col5a1RatSpontaneous Abortions  ISORGD:73343511554173CTD Direct Evidence: marker/mechanismCTDPMID:18539642
Col5a1RatSpontaneous Rupture  ISORGD:73343511554173CTD Direct Evidence: marker/mechanismCTDPMID:20635400
1 to 10 of 10 rows
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Original Reference(s)
Col5a1RatEhlers-Danlos syndrome classic type 1  ISSRGD:73343613592920OMIM:130000MouseDO 
Object Symbol
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With
Reference
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Original Reference(s)
Col5a1RatEhlers-Danlos syndrome classic type 1  ISORGD:7334357240710 OMIM 
Col5a1RatMultifocal Fibromuscular Dysplasia  ISORGD:7334357240710 OMIM 

1 to 20 of 218 rows

  
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Original Reference(s)
Col5a1Rat(1->4)-beta-D-glucan multiple interactionsISORGD:7334366480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of COL5A1 mRNACTDPMID:36331819
Col5a1Rat1,2-dimethylhydrazine multiple interactionsISORGD:7334366480464[1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of COL5A1 mRNACTDPMID:22206623
Col5a1Rat1-naphthyl isothiocyanate increases expressionEXP 64804641-Naphthylisothiocyanate results in increased expression of COL5A1 mRNACTDPMID:25380136
Col5a1Rat17alpha-ethynylestradiol affects expressionISORGD:7334366480464Ethinyl Estradiol affects the expression of COL5A1 mRNACTDPMID:17555576
Col5a1Rat17alpha-ethynylestradiol increases expressionISORGD:7334356480464Ethinyl Estradiol results in increased expression of COL5A1 mRNACTDPMID:18936297
Col5a1Rat17alpha-ethynylestradiol increases expressionISORGD:7334366480464Ethinyl Estradiol results in increased expression of COL5A1 mRNACTDPMID:17942748
Col5a1Rat17alpha-ethynylestradiol multiple interactionsISORGD:7334366480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of COL5A1 mRNACTDPMID:17942748
Col5a1Rat17alpha-ethynylestradiol affects expressionEXP 6480464Ethinyl Estradiol affects the expression of COL5A1 mRNACTDPMID:16079270
Col5a1Rat17alpha-ethynylestradiol increases expressionEXP 6480464Ethinyl Estradiol results in increased expression of COL5A1 mRNACTDPMID:12075121|PMID:12655037
Col5a1Rat17beta-estradiol decreases expressionISORGD:7334356480464Estradiol results in decreased expression of COL5A1 mRNACTDPMID:19167446
Col5a1Rat17beta-estradiol multiple interactionsEXP 6480464[estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of COL5A1 mRNACTDPMID:32741896
Col5a1Rat17beta-estradiol multiple interactionsISORGD:7334356480464[Estradiol co-treated with TGFB1 protein] results in increased expression of COL5A1 mRNACTDPMID:30165855
Col5a1Rat17beta-estradiol increases expressionISORGD:7334366480464Estradiol results in increased expression of COL5A1 mRNACTDPMID:19484750
Col5a1Rat17beta-estradiol 3-benzoate multiple interactionsEXP 6480464[estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of COL5A1 mRNACTDPMID:32741896
Col5a1Rat2,2',4,4'-Tetrabromodiphenyl ether increases expressionISORGD:73343564804642,2',4,4'-tetrabromodiphenyl ether results in increased expression of COL5A1 proteinCTDPMID:31675489
Col5a1Rat2,2',4,4'-Tetrabromodiphenyl ether multiple interactionsISORGD:7334366480464[Flame Retardants results in increased abundance of 2,2',4,4'-tetrabromodiphenyl ether] which results in decreased expression of more ...CTDPMID:38995820
Col5a1Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISORGD:7334366480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of COL5A1 mRNACTDPMID:17942748
Col5a1Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of COL5A1 mRNACTDPMID:33387578
Col5a1Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISORGD:7334356480464Tetrachlorodibenzodioxin affects the expression of COL5A1 mRNACTDPMID:36370075
Col5a1Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of COL5A1 mRNACTDPMID:34747641

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Biological Process
1 to 18 of 18 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Col5a1Ratbiological_process  ND 159840711/2008: no relevant rat dataRGD 
Col5a1Ratblood vessel development acts_upstream_of_or_withinISORGD:7334361624291MGI:3664598 PMID:16492673RGDPMID:16492673
Col5a1Ratcell adhesion involved_inISORGD:7334351624291 PMID:18305566RGDPMID:18305566
Col5a1Ratcell adhesion involved_inIBAPANTHER:PTN007763083|UniProtKB:P209081600115GO_REF:0000033GO_CentralGO_REF:0000033
Col5a1Ratcell migration involved_inISORGD:7334351624291 PMID:18305566RGDPMID:18305566
Col5a1Ratcollagen biosynthetic process involved_inISORGD:7334351624291 PMID:11278977, PMID:15095409RGDPMID:11278977|PMID:15095409
Col5a1Ratcollagen fibril organization involved_inISORGD:7334351624291 PMID:11278977, PMID:15095409, PMID:9683580RGDPMID:11278977|PMID:15095409|PMID:9683580
Col5a1Ratcollagen fibril organization acts_upstream_of_or_withinISORGD:7334361624291MGI:3664598|MGI:88446 PMID:15383546, PMID:16492673, PMID:17029294, PMID:21467034RGDPMID:15383546|PMID:16492673|PMID:17029294|PMID:21467034
Col5a1Ratcollagen fibril organization involved_inIBAMGI:88457|PANTHER:PTN007763083|UniProtKB:P209081600115GO_REF:0000033GO_CentralGO_REF:0000033
Col5a1Rateye morphogenesis involved_inISORGD:7334351624291 PMID:16431952RGDPMID:16431952
Col5a1Ratheart morphogenesis acts_upstream_of_or_withinISORGD:7334361624291MGI:88446 PMID:17029294RGDPMID:17029294
Col5a1Ratintegrin biosynthetic process involved_inISORGD:7334351624291 PMID:18305566RGDPMID:18305566
Col5a1Ratnegative regulation of endodermal cell differentiation involved_inISORGD:7334351624291 PMID:23154389RGDPMID:23154389
Col5a1Ratskin development involved_inISORGD:7334351624291 PMID:9683580RGDPMID:9683580
Col5a1Ratskin development acts_upstream_of_or_withinISORGD:7334361624291MGI:3664598 PMID:15383546, PMID:16492673RGDPMID:15383546|PMID:16492673
Col5a1Ratsupramolecular fiber organization involved_inISORGD:7334351624291 PMID:14970208RGDPMID:14970208
Col5a1Rattendon development acts_upstream_of_or_withinISORGD:7334361624291MGI:3664598|MGI:88446 PMID:21467034RGDPMID:21467034
Col5a1Ratwound healing, spreading of epidermal cells involved_inISORGD:7334351624291 PMID:18305566RGDPMID:18305566
1 to 18 of 18 rows

Cellular Component
1 to 11 of 11 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Col5a1Ratbasement membrane located_inISORGD:7334361624291 PMID:14676276RGDPMID:14676276
Col5a1Ratcollagen trimer part_ofIEAUniProtKB-KW:KW-01761600115GO_REF:0000043UniProtGO_REF:0000043
Col5a1Ratcollagen trimer part_ofISORGD:7334361624291MGI:3664598 PMID:15383546, PMID:16492673, PMID:17683922RGDPMID:15383546|PMID:16492673|PMID:17683922
Col5a1Ratcollagen type V trimer  TAS 70693 RGD 
Col5a1Ratcollagen type V trimer part_ofIBAPANTHER:PTN007763083|UniProtKB:P209081600115GO_REF:0000033GO_CentralGO_REF:0000033
Col5a1Ratcollagen type V trimer part_ofISORGD:7334351624291 PMID:9683580RGDPMID:9683580
Col5a1Ratcollagen-containing extracellular matrix located_inISORGD:7334351624291 PMID:14970208RGDPMID:14970208
Col5a1Ratcollagen-containing extracellular matrix is_active_inIBAFB:FBgn0000299|FB:FBgn0016075|MGI:104687|MGI:104688|MGI:1858212|MGI:2152695|MGI:2672118|MGI:2685312|MGI:88449|MGI:88451|MGI:88452|MGI:88453|MGI:88454|MGI:88455|MGI:88456|MGI:88457|MGI:88462|MGI:88467|MGI:88468|PANTHER:PTN001166351|RGD:2371|RGD:2372|RGD:2374|RGD:2375|RGD:70922|RGD:71029|UniProtKB:P02458|UniProtKB:P02461|UniProtKB:P02462|UniProtKB:P02467|UniProtKB:P05997|UniProtKB:P08123|UniProtKB:P12107|UniProtKB:P20908|UniProtKB:P53420|UniProtKB:Q01955|UniProtKB:Q03692|WB:WBGene00000527|WB:WBGene00001263|WB:WBGene000022801600115GO_REF:0000033GO_CentralGO_REF:0000033
Col5a1Ratextracellular matrix located_inISORGD:7334361624291 PMID:17029294RGDPMID:17029294
Col5a1Ratextracellular region located_inIEAUniProtKB-KW:KW-09641600115GO_REF:0000043UniProtGO_REF:0000043
Col5a1Ratextracellular space is_active_inIBAMGI:88452|MGI:88467|MGI:88468|PANTHER:PTN008390299|RGD:61817|RGD:70936|RGD:727898|UniProtKB:P02458|UniProtKB:P02461|UniProtKB:P08123|WB:WBGene000006741600115GO_REF:0000033GO_CentralGO_REF:0000033
1 to 11 of 11 rows

Molecular Function
1 to 11 of 11 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Col5a1Ratextracellular matrix structural constituent enablesIEAInterPro:IPR0008851600115GO_REF:0000002InterProGO_REF:0000002
Col5a1Ratextracellular matrix structural constituent enablesISORGD:7334361624291 PMID:15383546RGDPMID:15383546
Col5a1Ratextracellular matrix structural constituent conferring tensile strength enablesIBAPANTHER:PTN001166351|UniProtKB:P02462|WB:WBGene000022801600115GO_REF:0000033GO_CentralGO_REF:0000033
Col5a1Ratheparin binding  IDA 70693 RGD 
Col5a1Ratheparin binding enablesIEAUniProtKB-KW:KW-03581600115GO_REF:0000043UniProtGO_REF:0000043
Col5a1Ratheparin binding enablesIBAPANTHER:PTN007763083|RGD:70920|UniProtKB:P209081600115GO_REF:0000033GO_CentralGO_REF:0000033
Col5a1Ratheparin binding enablesISORGD:7334351624291 PMID:2203476RGDPMID:2203476
Col5a1Ratplatelet-derived growth factor binding enablesISORGD:7334351624291 PMID:8900172RGDPMID:8900172
Col5a1Ratprotein binding enablesISORGD:7334351624291UniProtKB:P01033|UniProtKB:P02751-1|UniProtKB:P08253|UniProtKB:P13497|UniProtKB:P17706|UniProtKB:P24821|UniProtKB:Q15113 PMID:20979576, PMID:28514442, PMID:33961781RGDPMID:20979576|PMID:28514442|PMID:33961781
Col5a1Ratprotein binding enablesISORGD:7334361624291PR:Q2QI47 PMID:14676276RGDPMID:14676276
Col5a1Ratproteoglycan binding enablesISORGD:7334351624291UniProtKB:Q00657 PMID:9099729RGDPMID:9099729
1 to 11 of 11 rows

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Col5a1Ratcell-extracellular matrix signaling pathway  IEA 6907045 KEGGrno:04512
Col5a1RatEntamoebiasis pathway  IEA 6907045 KEGGrno:05146

Imported Annotations - PID (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Col5a1Ratsyndecan signaling pathway  ISORGD:7334356484113 PIDPID:200156

1 to 17 of 17 rows
#
Reference Title
Reference Citation
1. COL5A1 exon 14 splice acceptor mutation causes a functional null allele, haploinsufficiency of alpha 1(V) and abnormal heterotypic interstitial fibrils in Ehlers-Danlos syndrome II. Bouma P, etal., J Biol Chem. 2001 Apr 20;276(16):13356-64. Epub 2001 Jan 19.
2. The gene encoding collagen alpha1(V)(COL5A1) is linked to mixed Ehlers-Danlos syndrome type I/II. Burrows NP, etal., J Invest Dermatol 1996 Jun;106(6):1273-6.
3. Schwann cells synthesize type V collagen that contains a novel alpha 4 chain. Molecular cloning, biochemical characterization, and high affinity heparin binding of alpha 4(V) collagen. Chernousov MA, etal., J Biol Chem 2000 Sep 8;275(36):28208-15.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
6. Gene Data Set MGD Curation, June 12, 2002
7. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
8. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
9. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
10. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
11. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
12. GOA pipeline RGD automated data pipeline
13. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
14. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
15. Comprehensive gene review and curation RGD comprehensive gene curation
16. Order of intron removal influences multiple splice outcomes, including a two-exon skip, in a COL5A1 acceptor-site mutation that results in abnormal pro-alpha1(V) N-propeptides and Ehlers-Danlos syndrome type I. Takahara K, etal., Am J Hum Genet. 2002 Sep;71(3):451-65. Epub 2002 Jul 17.
17. COL5A1 haploinsufficiency is a common molecular mechanism underlying the classical form of EDS. Wenstrup RJ, etal., Am J Hum Genet. 2000 Jun;66(6):1766-76. Epub 2000 Apr 24.
1 to 17 of 17 rows
PMID:2203476   PMID:8900172   PMID:9099729   PMID:9683580   PMID:9822201   PMID:12477932   PMID:14676276   PMID:14970208   PMID:15095409   PMID:15383546   PMID:16431952   PMID:16492673  
PMID:17029294   PMID:17683922   PMID:18305566   PMID:20551380   PMID:21467034   PMID:21713001   PMID:22206666   PMID:23154389   PMID:23376485   PMID:23658023   PMID:24006456   PMID:27068509  
PMID:27559042   PMID:35352799  



Col5a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8331,606,475 - 31,755,097 (+)NCBIGRCr8
mRatBN7.2311,208,429 - 11,356,715 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl311,208,512 - 11,354,588 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx314,276,142 - 14,421,992 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0322,861,404 - 23,007,143 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0321,115,526 - 21,261,367 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.036,430,180 - 6,581,010 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl36,430,201 - 6,578,882 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0311,788,675 - 11,937,880 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.436,826,169 - 6,971,054 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.136,826,468 - 6,971,354 (+)NCBI
Celera36,002,130 - 6,146,263 (+)NCBICelera
Cytogenetic Map3p12NCBI
COL5A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389134,641,803 - 134,844,843 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9134,641,803 - 134,844,843 (+)EnsemblGRCh38hg38GRCh38
GRCh379137,533,649 - 137,736,689 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369136,673,473 - 136,876,510 (+)NCBINCBI36Build 36hg18NCBI36
Build 349134,759,596 - 134,960,684NCBI
Celera9108,048,806 - 108,251,522 (+)NCBICelera
Cytogenetic Map9q34.3NCBI
HuRef9106,996,262 - 107,200,594 (+)NCBIHuRef
CHM1_19137,682,127 - 137,886,117 (+)NCBICHM1_1
T2T-CHM13v2.09146,859,174 - 147,065,950 (+)NCBIT2T-CHM13v2.0
Col5a1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39227,776,393 - 27,929,522 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl227,776,437 - 27,929,526 (+)EnsemblGRCm39 Ensembl
GRCm38227,886,381 - 28,039,510 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl227,886,425 - 28,039,514 (+)EnsemblGRCm38mm10GRCm38
MGSCv37227,741,945 - 27,895,030 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36227,708,694 - 27,859,533 (+)NCBIMGSCv36mm8
Celera227,589,197 - 27,742,307 (+)NCBICelera
Cytogenetic Map2A3NCBI
cM Map219.38NCBI
Col5a1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555133,533,614 - 3,658,161 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555133,533,612 - 3,660,605 (+)NCBIChiLan1.0ChiLan1.0
COL5A1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2114,523,306 - 4,731,588 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan194,525,346 - 4,733,918 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v09105,746,388 - 105,956,280 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19134,391,081 - 134,543,769 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9134,342,955 - 134,544,651 (+)Ensemblpanpan1.1panPan2
COL5A1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1950,706,852 - 50,856,691 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl950,770,277 - 50,854,728 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha949,989,837 - 50,140,047 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0951,583,512 - 51,733,920 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl951,583,513 - 51,732,204 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1950,343,968 - 50,494,164 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0950,687,121 - 50,838,052 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0950,765,252 - 50,915,697 (+)NCBIUU_Cfam_GSD_1.0
Col5a1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947200,761,510 - 200,900,677 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366692,476,818 - 2,580,891 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366692,474,381 - 2,613,541 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
COL5A1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1273,971,971 - 274,085,111 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11273,934,219 - 274,083,264 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21308,064,240 - 308,174,334 (+)NCBISscrofa10.2Sscrofa10.2susScr3
COL5A1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1123,301,643 - 3,507,300 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl123,301,175 - 3,459,607 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660581,612,962 - 1,827,783 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Col5a1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247602,593,961 - 2,713,772 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247602,593,923 - 2,713,772 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Col5a1
639 total Variants

Predicted Target Of
Summary Value
Count of predictions:104
Count of miRNA genes:80
Interacting mature miRNAs:90
Transcripts:ENSRNOT00000012334
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 22 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1558647Cm46Cardiac mass QTL 465.40.0000055heart mass (VT:0007028)heart wet weight (CMO:0000069)31077882330356773Rat
1358357Srcrtb1Stress Responsive Cort Basal QTL 16.360.002blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)3865816227494778Rat
6893355Bw101Body weight QTL 1010.40.38body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
4889966Bss95Bone structure and strength QTL 954.4tibia area (VT:1000281)tibia-fibula cross-sectional area (CMO:0001718)3136847613Rat
1558654Bw56Body weight QTL 564.50.0000171body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
10401810Kidm53Kidney mass QTL 53kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3822719447233430Rat
1298526Arunc3Aerobic running capacity QTL 32.2exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)3822719433703538Rat
8693641Alc30Alcohol consumption QTL 3020.739drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)31043430624512004Rat
1558650Cm48Cardiac mass QTL 4840.0001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)31077882330356773Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)31086191289878372Rat

1 to 10 of 22 rows
RH128099  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2311,355,049 - 11,355,252 (+)MAPPERmRatBN7.2
Rnor_6.036,579,338 - 6,579,540NCBIRnor6.0
Rnor_5.0311,936,213 - 11,936,415UniSTSRnor5.0
RGSC_v3.436,971,516 - 6,971,718UniSTSRGSC3.4
Celera36,146,725 - 6,146,927UniSTS
RH 3.4 Map319.2UniSTS
Cytogenetic Map3p12UniSTS
RH139630  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8331,734,668 - 31,735,039 (+)Marker Load Pipeline
mRatBN7.2311,336,631 - 11,337,002 (+)MAPPERmRatBN7.2
Rnor_6.036,560,920 - 6,561,290NCBIRnor6.0
Rnor_5.0311,917,795 - 11,918,165UniSTSRnor5.0
RGSC_v3.436,953,098 - 6,953,468UniSTSRGSC3.4
Celera36,128,250 - 6,128,620UniSTS
Cytogenetic Map3p12UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000012334   ⟹   ENSRNOP00000012334
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl311,208,835 - 11,354,588 (+)Ensembl
Rnor_6.0 Ensembl36,430,589 - 6,578,882 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000086352   ⟹   ENSRNOP00000070132
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl311,208,512 - 11,347,485 (+)Ensembl
Rnor_6.0 Ensembl36,430,201 - 6,571,377 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000110258   ⟹   ENSRNOP00000084311
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl311,240,164 - 11,354,588 (+)Ensembl
RefSeq Acc Id: NM_134452   ⟹   NP_604447
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8331,606,880 - 31,752,625 (+)NCBI
mRatBN7.2311,208,837 - 11,354,588 (+)NCBI
Rnor_6.036,430,591 - 6,578,876 (+)NCBI
Rnor_5.0311,788,675 - 11,937,880 (+)NCBI
RGSC_v3.436,826,169 - 6,971,054 (+)RGD
Celera36,002,130 - 6,146,263 (+)RGD
Sequence:
RefSeq Acc Id: XM_006233873   ⟹   XP_006233935
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8331,606,475 - 31,755,097 (+)NCBI
mRatBN7.2311,208,429 - 11,356,715 (+)NCBI
Rnor_6.036,430,180 - 6,581,010 (+)NCBI
Rnor_5.0311,788,675 - 11,937,880 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063284748   ⟹   XP_063140818
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8331,616,994 - 31,755,097 (+)NCBI
1 to 10 of 10 rows
Protein RefSeqs NP_001416521 (Get FASTA)   NCBI Sequence Viewer  
  NP_604447 (Get FASTA)   NCBI Sequence Viewer  
  XP_006233935 (Get FASTA)   NCBI Sequence Viewer  
  XP_063140818 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAF76433 (Get FASTA)   NCBI Sequence Viewer  
  CAA06509 (Get FASTA)   NCBI Sequence Viewer  
  EDL93427 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000104614
  ENSRNOP00000106819
GenBank Protein Q9JI03 (Get FASTA)   NCBI Sequence Viewer  
1 to 10 of 10 rows
RefSeq Acc Id: NP_604447   ⟸   NM_134452
- Peptide Label: precursor
- UniProtKB: Q9JI03 (UniProtKB/Swiss-Prot),   A6JTM0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006233935   ⟸   XM_006233873
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000012334   ⟸   ENSRNOT00000012334
Ensembl Acc Id: ENSRNOP00000070132   ⟸   ENSRNOT00000086352
Ensembl Acc Id: ENSRNOP00000084311   ⟸   ENSRNOT00000110258
Fibrillar collagen NC1   Laminin G-like

Name Modeler Protein Id AA Range Protein Structure
AF-Q9JI03-F1-model_v2 AlphaFold Q9JI03 1-1840 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13691952
Promoter ID:EPDNEW_R2453
Type:initiation region
Name:Col5a1_1
Description:collagen type V alpha 1 chain
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.036,430,230 - 6,430,290EPDNEW


1 to 32 of 32 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-50287 BioCyc
Ensembl Genes ENSRNOG00000008749 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000133981 ENTREZGENE
  ENSRNOT00000134795 ENTREZGENE
Gene3D-CATH 2.60.120.1000 UniProtKB/Swiss-Prot
  2.60.120.200 UniProtKB/Swiss-Prot
InterPro Collagen UniProtKB/Swiss-Prot
  Collagen_superfamily UniProtKB/Swiss-Prot
  ConA-like_dom_sf UniProtKB/Swiss-Prot
  Fib_collagen_C UniProtKB/Swiss-Prot
  Laminin_G UniProtKB/Swiss-Prot
  TSPN-like_N UniProtKB/Swiss-Prot
KEGG Report rno:85490 UniProtKB/Swiss-Prot
NCBI Gene 85490 ENTREZGENE
PANTHER COLLAGEN ALPHA UniProtKB/Swiss-Prot
  COLLAGEN ALPHA-4(IV) CHAIN-LIKE UniProtKB/Swiss-Prot
Pfam COLFI UniProtKB/Swiss-Prot
  Collagen UniProtKB/Swiss-Prot
  Laminin_G_2 UniProtKB/Swiss-Prot
PhenoGen Col5a1 PhenoGen
PROSITE NC1_FIB UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000008749 RatGTEx
SMART COLFI UniProtKB/Swiss-Prot
  LamG UniProtKB/Swiss-Prot
  TSPN UniProtKB/Swiss-Prot
Superfamily-SCOP SSF49899 UniProtKB/Swiss-Prot
UniProt A0A0G2JX47_RAT UniProtKB/TrEMBL
  A0A8I6GA68 ENTREZGENE, UniProtKB/TrEMBL
  A6JTM0 ENTREZGENE, UniProtKB/TrEMBL
  CO5A1_RAT UniProtKB/Swiss-Prot
  G3V763 ENTREZGENE, UniProtKB/TrEMBL
  Q9JI03 ENTREZGENE
1 to 32 of 32 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-07-27 Col5a1  collagen type V alpha 1 chain  Col5a1  collagen, type V, alpha 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-25 Col5a1  collagen, type V, alpha 1  Col5a1  procollagen, type V, alpha 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Col5a1  procollagen, type V, alpha 1    collagen, type V, alpha 1  Name updated 1299863 APPROVED
2002-07-09 Col5a1  collagen, type V, alpha 1      Symbol and Name updated to reflect Human and Mouse nomenclature 70877 APPROVED

Note Type Note Reference
gene_function binds heparin with high affinity 70693