Nedd9 (neural precursor cell expressed, developmentally down-regulated 9) - Rat Genome Database

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Gene: Nedd9 (neural precursor cell expressed, developmentally down-regulated 9) Rattus norvegicus
Analyze
Symbol: Nedd9
Name: neural precursor cell expressed, developmentally down-regulated 9
RGD ID: 1306276
Description: Predicted to enable protein tyrosine kinase binding activity. Predicted to be involved in several processes, including positive regulation of dendritic spine maintenance; positive regulation of immunological synapse formation; and regulation of cell migration. Predicted to be located in several cellular components, including basolateral plasma membrane; focal adhesion; and microtubule cytoskeleton. Predicted to be active in cytoplasm. Predicted to colocalize with plasma membrane. Orthologous to human NEDD9 (neural precursor cell expressed, developmentally down-regulated 9); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: enhancer of filamentation 1; LOC291044; neural precursor cell expressed, developmentally down-regulated gene 9
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81723,495,531 - 23,673,780 (+)NCBIGRCr8
mRatBN7.21723,289,793 - 23,468,026 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1723,282,326 - 23,468,019 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1723,287,211 - 23,337,016 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01724,890,899 - 24,940,705 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01723,228,163 - 23,277,968 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01722,984,792 - 23,179,701 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1722,984,844 - 23,179,701 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01725,019,957 - 25,143,758 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41729,304,750 - 29,354,613 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11729,307,590 - 29,357,454 (+)NCBI
Celera1723,088,684 - 23,138,480 (+)NCBICelera
Cytogenetic Map17p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
(S)-nicotine  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,3-dimethoxynaphthalene-1,4-dione  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-amino-4,6-dinitrotoluene  (EXP)
3,4-dichloroaniline  (EXP,ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-methylcholanthrene  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
9-cis-retinoic acid  (ISO)
acetamide  (EXP)
actinomycin D  (ISO)
aflatoxin B1  (EXP,ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-4-oxoretinoic acid  (ISO)
all-trans-retinoic acid  (EXP,ISO)
amphotericin B  (ISO)
antirheumatic drug  (ISO)
Aroclor 1254  (ISO)
benzene  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
chloroacetaldehyde  (ISO)
chloroprene  (ISO)
chlorpromazine  (EXP)
choline  (ISO)
cidofovir anhydrous  (ISO)
cisplatin  (ISO)
clodronic acid  (ISO)
cobalt dichloride  (EXP,ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (EXP,ISO)
cylindrospermopsin  (ISO)
dibutyl phthalate  (ISO)
dichloromethane  (ISO)
diethylstilbestrol  (EXP)
dioxygen  (ISO)
disodium selenite  (ISO)
diuron  (EXP,ISO)
divanadium pentaoxide  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
Enterolactone  (ISO)
entinostat  (ISO)
ethylbenzene  (ISO)
etoposide  (ISO)
fenofibrate  (EXP,ISO)
fenthion  (ISO)
ferric oxide  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
geldanamycin  (ISO)
gemcitabine  (ISO)
genistein  (ISO)
glycidol  (EXP)
GW 501516  (ISO)
ibuprofen  (EXP,ISO)
ifosfamide  (ISO)
indometacin  (ISO)
iron atom  (EXP)
iron(0)  (EXP)
isotretinoin  (ISO)
L-methionine  (ISO)
leflunomide  (ISO)
levofloxacin  (EXP)
lipopolysaccharide  (ISO)
metformin  (EXP)
methapyrilene  (ISO)
methylisothiazolinone  (ISO)
methylmercury chloride  (ISO)
mitomycin C  (ISO)
N-acetyl-L-cysteine  (ISO)
nickel sulfate  (ISO)
nicotine  (ISO)
o-xylene  (ISO)
oxaliplatin  (EXP)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
propiconazole  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
rotenone  (EXP,ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
Soman  (EXP)
sotorasib  (ISO)
sunitinib  (ISO)
tacedinaline  (ISO)
tamoxifen  (ISO)
temozolomide  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
tetraphene  (ISO)
toluene  (ISO)
topotecan  (EXP)
trametinib  (ISO)
trichloroethene  (EXP,ISO)
trichostatin A  (ISO)
triphenyl phosphate  (EXP)
triticonazole  (EXP)
troglitazone  (EXP)
trovafloxacin  (ISO)
tungsten  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
vanadium atom  (ISO)
vanadium(0)  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:15376324   PMID:16210561   PMID:18256281   PMID:19376971   PMID:25621495   PMID:27085739  


Genomics

Comparative Map Data
Nedd9
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81723,495,531 - 23,673,780 (+)NCBIGRCr8
mRatBN7.21723,289,793 - 23,468,026 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1723,282,326 - 23,468,019 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1723,287,211 - 23,337,016 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01724,890,899 - 24,940,705 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01723,228,163 - 23,277,968 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01722,984,792 - 23,179,701 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1722,984,844 - 23,179,701 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01725,019,957 - 25,143,758 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41729,304,750 - 29,354,613 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11729,307,590 - 29,357,454 (+)NCBI
Celera1723,088,684 - 23,138,480 (+)NCBICelera
Cytogenetic Map17p12NCBI
NEDD9
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38611,183,298 - 11,382,348 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl611,183,298 - 11,382,348 (-)EnsemblGRCh38hg38GRCh38
GRCh37611,183,531 - 11,382,581 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36611,291,519 - 11,340,887 (-)NCBINCBI36Build 36hg18NCBI36
Celera612,411,994 - 12,611,049 (-)NCBICelera
Cytogenetic Map6p24.2NCBI
HuRef611,114,819 - 11,313,849 (-)NCBIHuRef
CHM1_1611,185,979 - 11,385,008 (-)NCBICHM1_1
T2T-CHM13v2.0611,051,218 - 11,250,286 (-)NCBIT2T-CHM13v2.0
Nedd9
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391341,463,392 - 41,640,836 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1341,463,057 - 41,640,838 (-)EnsemblGRCm39 Ensembl
GRCm381341,309,916 - 41,487,362 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1341,309,581 - 41,487,362 (-)EnsemblGRCm38mm10GRCm38
MGSCv371341,405,285 - 41,582,689 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361341,320,960 - 41,498,261 (-)NCBIMGSCv36mm8
Celera1342,392,251 - 42,568,113 (-)NCBICelera
Cytogenetic Map13A3.3- A4NCBI
cM Map1320.43NCBI
Nedd9
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554653,129,707 - 3,282,632 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554653,101,409 - 3,281,481 (+)NCBIChiLan1.0ChiLan1.0
NEDD9
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2525,830,897 - 25,880,332 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1621,820,942 - 21,870,381 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0611,022,321 - 11,071,747 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1611,297,701 - 11,346,973 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl611,297,701 - 11,420,186 (-)Ensemblpanpan1.1panPan2
NEDD9
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13510,852,334 - 11,033,656 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3510,854,295 - 10,964,650 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3510,801,380 - 10,984,979 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03510,954,569 - 11,138,759 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3510,954,585 - 11,138,702 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13510,785,077 - 10,968,606 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03510,833,555 - 11,017,186 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03512,155,116 - 12,341,102 (-)NCBIUU_Cfam_GSD_1.0
Nedd9
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494613,448,398 - 13,594,214 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365341,760,142 - 1,863,565 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365341,816,755 - 1,863,200 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NEDD9
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl77,807,044 - 7,914,061 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.177,807,042 - 8,093,553 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.278,268,188 - 8,442,553 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NEDD9
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11760,759,411 - 60,959,558 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1760,911,264 - 60,959,603 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604411,216,443 - 11,417,455 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nedd9
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475614,737,054 - 14,850,708 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475614,663,114 - 14,850,132 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Nedd9
1239 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:189
Count of miRNA genes:153
Interacting mature miRNAs:171
Transcripts:ENSRNOT00000067374
Prediction methods:Miranda, Pita
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10401807Kidm52Kidney mass QTL 52kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17131701463Rat
70184BpQTLcluster14Blood pressure QTL cluster 143.38arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)17131990913Rat
631207Niddm41Non-insulin dependent diabetes mellitus QTL 41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)17137830672Rat
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17160781592Rat
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17169599340Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17169599340Rat
1300123Bp194Blood pressure QTL 1942.82arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)17211514934551001Rat
631499Stl1Serum triglyceride level QTL 13.6blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)17327139827389946Rat
1354613Kidm14Kidney mass QTL 146.2kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)17429913035837242Rat
1354596Bw32Body weight QTL 324.5body mass (VT:0001259)body weight (CMO:0000012)17429913060781592Rat
1354630Cm34Cardiac mass QTL 348.7heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)17429913069599340Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)17429913069599340Rat
1354651Lmblg2Limb length QTL 26tibia length (VT:0004357)tibia length (CMO:0000450)17429913069599340Rat
2293648Bmd31Bone mineral density QTL 314.50.0001femur size trait (VT:1000369)femoral neck cortical cross-sectional area (CMO:0001702)17435448727028127Rat
2293664Bmd28Bone mineral density QTL 285.10.0001femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)17435448727028127Rat
2303627Vencon8Ventilatory control QTL 80.001respiration trait (VT:0001943)tidal volume (CMO:0000222)17452803849528038Rat
10054088Scort28Serum corticosterone level QTL 282.040.0102blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17452803849528038Rat
2303561Bw91Body weight QTL 912body mass (VT:0001259)body weight (CMO:0000012)17886846253868462Rat
1582199Insul5Insulin level QTL 53.40.0119blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)17920136523653323Rat
1582208Kidm32Kidney mass QTL 323.90.0018kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17920136523653323Rat
1582224Epfw4Epididymal fat weight QTL 43.50.0058epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)17920136523653323Rat
1582225Bw67Body weight QTL 676.20.0001body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
1582226Bw64Body weight QTL 644.20.0017body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
1582241Bw70Body weight QTL 704.60.0003body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
1582245Bw73Body weight QTL 734.60.0004body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
1582258Bw76Body weight QTL 764.60.0005body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
2300002Iddm36Insulin dependent diabetes mellitus QTL 361.98blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)17999128640540197Rat
1331765Hrtrt15Heart rate QTL 154.094heart pumping trait (VT:2000009)heart rate (CMO:0000002)171533061355836425Rat
1354640Scl32Serum cholesterol level QTL 325.4blood HDL cholesterol amount (VT:0000184)blood high density lipoprotein cholesterol level (CMO:0000052)171578159260781592Rat
1354659Scl68Serum cholesterol level QTL 683.9blood VLDL cholesterol amount (VT:0005144)blood very low density lipoprotein cholesterol level (CMO:0000648)171578159260781592Rat
7394837Memor18Memory QTL 18exploratory behavior trait (VT:0010471)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)171864018263640182Rat
1354628Stl13Serum triglyceride level QTL 133.8blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)172129303960781592Rat
70157Niddm32Non-insulin dependent diabetes mellitus QTL 324.34blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)172245492450909196Rat
61394Bp8Blood pressure QTL 82.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172308056759555013Rat

Markers in Region
RH136902  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21723,467,765 - 23,467,945 (+)MAPPERmRatBN7.2
Rnor_6.01723,179,441 - 23,179,620NCBIRnor6.0
Rnor_5.01725,143,490 - 25,143,669UniSTSRnor5.0
RGSC_v3.41729,354,353 - 29,354,532UniSTSRGSC3.4
Celera1723,138,220 - 23,138,399UniSTS
RH 3.4 Map17279.7UniSTS
Cytogenetic Map17p12UniSTS
RH141358  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21723,467,700 - 23,467,912 (+)MAPPERmRatBN7.2
Rnor_6.01723,179,376 - 23,179,587NCBIRnor6.0
Rnor_5.01725,143,425 - 25,143,636UniSTSRnor5.0
RGSC_v3.41729,354,288 - 29,354,499UniSTSRGSC3.4
Celera1723,138,155 - 23,138,366UniSTS
RH 3.4 Map17278.1UniSTS
Cytogenetic Map17p12UniSTS
RH144310  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21723,466,409 - 23,466,533 (+)MAPPERmRatBN7.2
Rnor_6.01723,178,085 - 23,178,208NCBIRnor6.0
Rnor_5.01725,142,134 - 25,142,257UniSTSRnor5.0
RGSC_v3.41729,352,997 - 29,353,120UniSTSRGSC3.4
Celera1723,136,870 - 23,136,993UniSTS
RH 3.4 Map17277.4UniSTS
Cytogenetic Map17p12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 28 16 8 19 8 1 1 27 33 33 11 1
Low 15 41 33 33 7 9 47 2 8 7
Below cutoff 1

Sequence


RefSeq Acc Id: ENSRNOT00000067374   ⟹   ENSRNOP00000060831
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1723,418,203 - 23,468,019 (+)Ensembl
Rnor_6.0 Ensembl1723,116,661 - 23,179,701 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000078310   ⟹   ENSRNOP00000071096
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1723,282,326 - 23,468,019 (+)Ensembl
Rnor_6.0 Ensembl1722,984,844 - 23,178,516 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000090794   ⟹   ENSRNOP00000074425
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1723,135,985 - 23,177,936 (+)Ensembl
RefSeq Acc Id: NM_001011922   ⟹   NP_001011922
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81723,623,961 - 23,673,780 (+)NCBI
mRatBN7.21723,418,202 - 23,468,026 (+)NCBI
Rnor_6.01723,116,661 - 23,179,701 (+)NCBI
Rnor_5.01725,019,957 - 25,143,758 (+)NCBI
RGSC_v3.41729,304,750 - 29,354,613 (+)RGD
Celera1723,088,684 - 23,138,480 (+)RGD
Sequence:
RefSeq Acc Id: XM_006253786   ⟹   XP_006253848
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81723,495,531 - 23,673,778 (+)NCBI
mRatBN7.21723,289,793 - 23,468,024 (+)NCBI
Rnor_6.01722,984,792 - 23,179,699 (+)NCBI
Rnor_5.01725,019,957 - 25,143,758 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039095477   ⟹   XP_038951405
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81723,643,129 - 23,673,778 (+)NCBI
mRatBN7.21723,437,374 - 23,468,025 (+)NCBI
RefSeq Acc Id: NP_001011922   ⟸   NM_001011922
- UniProtKB: Q5U2Y4 (UniProtKB/TrEMBL),   A6J767 (UniProtKB/TrEMBL),   F7F3Z5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006253848   ⟸   XM_006253786
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JZL7 (UniProtKB/TrEMBL),   A6J766 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000060831   ⟸   ENSRNOT00000067374
RefSeq Acc Id: ENSRNOP00000074425   ⟸   ENSRNOT00000090794
RefSeq Acc Id: ENSRNOP00000071096   ⟸   ENSRNOT00000078310
RefSeq Acc Id: XP_038951405   ⟸   XM_039095477
- Peptide Label: isoform X2
Protein Domains
SH3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JZL7-F1-model_v2 AlphaFold A0A0G2JZL7 1-897 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700382
Promoter ID:EPDNEW_R10906
Type:multiple initiation site
Name:Nedd9_1
Description:neural precursor cell expressed, developmentally down-regulated9
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R10907  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01723,116,644 - 23,116,704EPDNEW
RGD ID:13700391
Promoter ID:EPDNEW_R10907
Type:initiation region
Name:Nedd9_2
Description:neural precursor cell expressed, developmentally down-regulated9
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R10906  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01723,135,975 - 23,136,035EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306276 AgrOrtholog
BioCyc Gene G2FUF-9750 BioCyc
Ensembl Genes ENSRNOG00000014548 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000067374 ENTREZGENE
  ENSRNOT00000067374.3 UniProtKB/TrEMBL
  ENSRNOT00000078310.2 UniProtKB/TrEMBL
Gene3D-CATH 1.20.120.830 UniProtKB/TrEMBL
  Alpha-catenin/vinculin-like UniProtKB/TrEMBL
  SH3 Domains UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7121465 IMAGE-MGC_LOAD
InterPro CAS_DUF3513 UniProtKB/TrEMBL
  CAS_fam UniProtKB/TrEMBL
  NEDD9_SH3 UniProtKB/TrEMBL
  Serine_rich UniProtKB/TrEMBL
  Serine_rich_sf UniProtKB/TrEMBL
  SH3-like_dom UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
KEGG Report rno:291044 UniProtKB/TrEMBL
MGC_CLONE MGC:94019 IMAGE-MGC_LOAD
NCBI Gene 291044 ENTREZGENE
PANTHER ENHANCER OF FILAMENTATION 1 UniProtKB/TrEMBL
  PTHR10654 UniProtKB/TrEMBL
Pfam DUF3513 UniProtKB/TrEMBL
  Serine_rich UniProtKB/TrEMBL
  SH3_9 UniProtKB/TrEMBL
PhenoGen Nedd9 PhenoGen
PROSITE SH3 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000014548 RatGTEx
SMART SH3 UniProtKB/TrEMBL
Superfamily-SCOP SH3 UniProtKB/TrEMBL
UniProt A0A0G2JZL7 ENTREZGENE, UniProtKB/TrEMBL
  A6J766 ENTREZGENE, UniProtKB/TrEMBL
  A6J767 ENTREZGENE, UniProtKB/TrEMBL
  F7F3Z5 ENTREZGENE, UniProtKB/TrEMBL
  Q5U2Y4 ENTREZGENE
UniProt Secondary Q5U2Y4 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-09-25 Nedd9  neural precursor cell expressed, developmentally down-regulated 9  Nedd9  neural precursor cell expressed, developmentally down-regulated gene 9  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Nedd9  neural precursor cell expressed, developmentally down-regulated gene 9  Nedd9_predicted  neural precursor cell expressed, developmentally down-regulated gene 9 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Nedd9_predicted  neural precursor cell expressed, developmentally down-regulated gene 9 (predicted)      Symbol and Name status set to approved 70820 APPROVED