Gene: Mfn1 (mitofusin 1) Rattus norvegicus
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Symbol: Mfn1
Name: mitofusin 1
Description: ENCODES a protein that exhibits protein homodimerization activity; GTPase activity (ortholog); INVOLVED IN cellular response to dexamethasone stimulus; cellular response to glucose stimulus; cellular response to hypoxia; PARTICIPATES IN mitochondria fusion pathway; ASSOCIATED WITH Acute Heart Injury; acute kidney failure; Acute Lung Injury; FOUND IN mitochondrial inner membrane; mitochondrial outer membrane; integral component of membrane (ortholog); INTERACTS WITH 2,6-dinitrotoluene; 4-DAMP(1+); 6-propyl-2-thiouracil
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Fzo1b; mitochondrial transmembrane GTPase FZO1B; mitofusin-1; transmembrane GTPase MFN1
Orthologs:
Homo sapiens (human) : MFN1 (mitofusin 1)  HGNC  Alliance
Mus musculus (house mouse) : Mfn1 (mitofusin 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mfn1 (mitofusin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MFN1 (mitofusin 1)
Canis lupus familiaris (dog) : MFN1 (mitofusin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mfn1 (mitofusin 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02118,929,738 - 118,971,689 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02138,586,943 - 138,627,280 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42118,739,155 - 118,783,037 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12118,684,116 - 118,727,999 (+)NCBI
Celera2110,426,431 - 110,467,687 (+)NCBICelera
Cytogenetic Map2q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Mfn1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621460
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2018-08-21
Status: ACTIVE