Gene: Timp1 (TIMP metallopeptidase inhibitor 1) Rattus norvegicus
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Symbol: Timp1
Name: TIMP metallopeptidase inhibitor 1
Description: ENCODES a protein that exhibits protease binding; cytokine activity (ortholog); metalloendopeptidase inhibitor activity (ortholog); INVOLVED IN aging; cartilage development; cell activation; PARTICIPATES IN interleukin-6 signaling pathway; ASSOCIATED WITH Brain Injuries; cholestasis; chronic obstructive pulmonary disease; FOUND IN basement membrane; extracellular matrix (ortholog); extracellular space (ortholog); INTERACTS WITH (R)-carnitine; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; (S)-colchicine
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: metalloproteinase inhibitor 1; Timp; TIMP-1; tissue inhibitor of metallopeptidase 1; tissue inhibitor of metalloproteinase 1; tissue inhibitor of metalloproteinases 1
Orthologs:
Homo sapiens (human) : TIMP1 (TIMP metallopeptidase inhibitor 1)  HGNC  Alliance
Mus musculus (house mouse) : Timp1 (tissue inhibitor of metalloproteinase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Timp1 (TIMP metallopeptidase inhibitor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TIMP1 (TIMP metallopeptidase inhibitor 1)
Canis lupus familiaris (dog) : TIMP1 (TIMP metallopeptidase inhibitor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Timp1 (TIMP metallopeptidase inhibitor 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X1,364,771 - 1,369,451 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X2,179,962 - 2,184,814 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X12,542,496 - 12,547,094 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X12,548,051 - 12,552,650 (-)NCBI
CeleraX1,780,586 - 1,785,184 (-)NCBICelera
Cytogenetic MapXq11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Timp1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621675
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2018-10-09
Status: ACTIVE