(-)-demecolcine increases expression ISO RGD:1347215 6480464 Demecolcine results in increased expression of TIMP1 mRNA CTD PMID:23649840 (-)-epigallocatechin 3-gallate multiple interactions ISO RGD:731433 6480464 epigallocatechin gallate inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA] CTD PMID:20438794 (2R,4R)-1-[(2S)-5-(diaminomethylideneamino)-2-[(3-methyl-1,2,3,4-tetrahydroquinolin-8-yl)sulfonylamino]-1-oxopentyl]-4-methyl-2-piperidinecarboxylic acid multiple interactions ISO RGD:731433 6480464 argatroban inhibits the reaction [Dietary Fats results in increased expression of TIMP1 mRNA] CTD PMID:22841818 (R)-carnitine multiple interactions EXP 6480464 Carnitine inhibits the reaction [sunitinib results in increased expression of TIMP1 mRNA] CTD PMID:26581635 (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of TIMP1 mRNA CTD PMID:25729387 (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE increases expression EXP 6480464 Topotecan results in increased expression of TIMP1 mRNA CTD PMID:25729387 (S)-colchicine increases expression EXP 6480464 Colchicine results in increased expression of TIMP1 mRNA CTD PMID:20624997 (S)-nicotine multiple interactions ISO RGD:1347215 6480464 [Nicotine co-treated with lipopolysaccharide, E. coli O26-B6] affects the expression of TIMP1 mRNA CTD PMID:18986645 (S)-nicotine affects expression ISO RGD:1347215 6480464 Nicotine affects the expression of TIMP1 mRNA CTD PMID:18986645 1,1-dichloroethene increases expression ISO RGD:731433 6480464 vinylidene chloride results in increased expression of TIMP1 mRNA CTD PMID:26682919 1,2,4-trimethylbenzene increases expression EXP 6480464 pseudocumene results in increased expression of TIMP1 protein CTD PMID:17337753 1,3,5-trinitro-1,3,5-triazinane increases expression EXP 6480464 cyclonite results in increased expression of TIMP1 mRNA CTD PMID:25559034 1-chloro-2,4-dinitrobenzene affects expression ISO RGD:731433 6480464 Dinitrochlorobenzene affects the expression of TIMP1 mRNA CTD PMID:22302311 1-naphthyl isothiocyanate increases expression EXP 6480464 1-Naphthylisothiocyanate results in increased expression of TIMP1 mRNA CTD PMID:17522070 more ... 1-naphthyl isothiocyanate multiple interactions ISO RGD:731433 6480464 F2R protein promotes the reaction [1-Naphthylisothiocyanate results in increased expression of TIMP1 mRNA] more ... CTD PMID:21037076 , PMID:24633426 1-naphthyl isothiocyanate increases expression ISO RGD:731433 6480464 1-Naphthylisothiocyanate results in increased expression of TIMP1 mRNA, 1-Naphthylisothiocyanate results in increased expression of TIMP1 protein CTD PMID:21037076 more ... 1-octadec-9-enoylglycero-3-phosphate multiple interactions ISO RGD:731433 6480464 3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl amino)-3-methyl-5-isoxazolyl) benzylsulfanyl) propanoic acid inhibits the reaction [lysophosphatidic acid results in increased expression of TIMP1 protein] CTD PMID:25822713 1-octadec-9-enoylglycero-3-phosphate increases expression ISO RGD:731433 6480464 lysophosphatidic acid results in increased expression of TIMP1 protein CTD PMID:25822713 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of TIMP1 mRNA CTD PMID:17557909 17alpha-ethynylestradiol affects expression EXP 6480464 Ethinyl Estradiol affects the expression of TIMP1 mRNA CTD PMID:16079270 17beta-estradiol decreases expression ISO RGD:1347215 6480464 Estradiol results in decreased expression of TIMP1 mRNA CTD PMID:16202921 17beta-estradiol increases expression ISO RGD:731433 6480464 Estradiol results in increased expression of TIMP1 mRNA CTD PMID:19484750 17beta-estradiol increases expression ISO RGD:1347215 6480464 Estradiol results in increased expression of TIMP1 mRNA CTD PMID:20106945 , PMID:21632981 17beta-estradiol multiple interactions ISO RGD:1347215 6480464 [Estradiol co-treated with EGF protein] results in increased expression of TIMP1 mRNA, [Progesterone co-treated with Estradiol] results in increased expression of TIMP1 mRNA CTD PMID:20226447 , PMID:24758408 2,2',4,4'-Tetrabromodiphenyl ether increases expression EXP 6480464 2 more ... CTD PMID:21394737 2,2,2-trichloroethanol increases expression ISO RGD:1347215 6480464 2 more ... CTD PMID:21741468 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:731433 6480464 [Tetrachlorodibenzodioxin co-treated with Carbon Tetrachloride] results in increased expression of TIMP1 mRNA more ... CTD PMID:16054899 , PMID:27693115 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of TIMP1 mRNA CTD PMID:15644576 more ... 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:731433 6480464 Tetrachlorodibenzodioxin affects the expression of TIMP1 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:731433 6480464 Tetrachlorodibenzodioxin results in increased expression of TIMP1 mRNA CTD PMID:19770486 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:731433 6480464 Tetrachlorodibenzodioxin results in decreased expression of TIMP1 mRNA CTD PMID:16054899 , PMID:17586704 2,3-dimethoxynaphthalene-1,4-dione increases expression ISO RGD:1347215 6480464 2 more ... CTD PMID:17547211 2,4,6-trinitrobenzenesulfonic acid multiple interactions ISO RGD:731433 6480464 Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TIMP1 mRNA] CTD PMID:18200517 2,4,6-trinitrobenzenesulfonic acid multiple interactions EXP 6480464 ilomastat affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TIMP1 mRNA], ilomastat affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TIMP1 protein] CTD PMID:18837084 2,4,6-trinitrobenzenesulfonic acid increases expression EXP 6480464 Trinitrobenzenesulfonic Acid results in increased expression of TIMP1 mRNA, Trinitrobenzenesulfonic Acid results in increased expression of TIMP1 protein CTD PMID:18837084 2,4,6-trinitrobenzenesulfonic acid increases expression ISO RGD:731433 6480464 Trinitrobenzenesulfonic Acid results in increased expression of TIMP1 mRNA CTD PMID:17982090 , PMID:18200517 2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione multiple interactions EXP 6480464 Thalidomide inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA] more ... CTD PMID:15464241 , PMID:17030452 2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile affects expression ISO RGD:1347215 6480464 Verapamil affects the expression of TIMP1 protein CTD PMID:12388792 2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile multiple interactions EXP 6480464 Verapamil inhibits the reaction [ferrous sulfate results in increased expression of TIMP1 protein] CTD PMID:27095094 2-acetamidofluorene increases expression EXP 6480464 2-Acetylaminofluorene results in increased expression of TIMP1 mRNA CTD PMID:18678246 2-amino-2-deoxy-D-glucopyranose multiple interactions EXP 6480464 Glucosamine inhibits the reaction [IL1B results in increased expression of TIMP1 mRNA], IL1B promotes the reaction [Glucosamine results in increased expression of TIMP1 mRNA] CTD PMID:17109745 2-amino-2-deoxy-D-glucopyranose increases expression EXP 6480464 Glucosamine results in increased expression of TIMP1 mRNA CTD PMID:17109745 2-butoxyethanol increases expression ISO RGD:731433 6480464 n-butoxyethanol results in increased expression of TIMP1 mRNA CTD PMID:19812364 2-HYDROXY-(5-([4-(2-PYRIDINYLAMINO)SULFONYL]PHENYL)AZO)BENZOIC ACID multiple interactions EXP 6480464 Sulfasalazine inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 protein] CTD PMID:15633128 2-nitrofluorene increases expression EXP 6480464 2-nitrofluorene results in increased expression of TIMP1 mRNA CTD PMID:14600272 , PMID:15890375 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine multiple interactions EXP 6480464 FR 139317 inhibits the reaction [Puromycin Aminonucleoside results in increased expression of TIMP1 mRNA] CTD PMID:9175058 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine increases expression EXP 6480464 Puromycin Aminonucleoside results in increased expression of TIMP1 mRNA CTD PMID:9175058 3,3',4,4',5-pentachlorobiphenyl increases expression ISO RGD:731433 6480464 3 more ... CTD PMID:28163111 3,3',4,4',5-pentachlorobiphenyl multiple interactions ISO RGD:731433 6480464 3 more ... CTD PMID:28163111 , PMID:28973532 3,3',5,5'-tetrabromobisphenol A increases expression ISO RGD:731433 6480464 tetrabromobisphenol A results in increased expression of TIMP1 mRNA CTD PMID:25172293 3,3',5,5'-tetrabromobisphenol A decreases expression EXP 6480464 tetrabromobisphenol A results in decreased expression of TIMP1 mRNA CTD PMID:28300664 3,3'-diindolylmethane increases expression ISO RGD:1347215 6480464 3, 3'-diindolylmethane analog results in increased expression of TIMP1 protein CTD PMID:25794856 3,4-dichloroaniline increases expression ISO RGD:1347215 6480464 3, 4-dichloroaniline results in increased expression of TIMP1 mRNA CTD PMID:24172598 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:731433 6480464 [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of TIMP1 mRNA more ... CTD PMID:16054899 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:1347215 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of TIMP1 mRNA CTD PMID:28628672 3-methylcholanthrene increases expression ISO RGD:1347215 6480464 Methylcholanthrene results in increased expression of TIMP1 mRNA CTD PMID:22579512 4,4'-diaminodiphenylmethane increases expression EXP 6480464 4, 4'-diaminodiphenylmethane results in increased expression of TIMP1 mRNA CTD PMID:25380136 4,4'-diaminodiphenylmethane decreases expression EXP 6480464 4, 4'-diaminodiphenylmethane results in decreased expression of TIMP1 mRNA CTD PMID:18289764 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one increases expression EXP 6480464 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of TIMP1 mRNA CTD PMID:14600272 , PMID:15890375 4-hydroxynon-2-enal decreases expression ISO RGD:731433 6480464 4-hydroxy-2-nonenal results in decreased expression of TIMP1 mRNA CTD PMID:19191707 4-hydroxynon-2-enal increases expression ISO RGD:1347215 6480464 4-hydroxy-2-nonenal results in increased expression of TIMP1 mRNA CTD PMID:14672615 4-hydroxyphenyl retinamide increases expression ISO RGD:731433 6480464 Fenretinide results in increased expression of TIMP1 mRNA CTD PMID:28973697 5-(1,4-diazepane-1-sulfonyl)isoquinoline affects expression ISO RGD:731433 6480464 fasudil affects the expression of TIMP1 mRNA CTD PMID:22465603 5-azacytidine increases expression ISO RGD:1347215 6480464 Azacitidine results in increased expression of TIMP1 mRNA CTD PMID:20823114 7,12-dimethyltetraphene decreases expression EXP 6480464 9 more ... CTD PMID:12097258 acetylsalicylic acid increases expression ISO RGD:1347215 6480464 Aspirin results in increased expression of TIMP1 mRNA CTD PMID:18971601 acetylsalicylic acid increases secretion ISO RGD:731433 6480464 Aspirin results in increased secretion of TIMP1 protein CTD PMID:19462226 acetylsalicylic acid increases expression ISO RGD:731433 6480464 Aspirin results in increased expression of TIMP1 mRNA CTD PMID:19462226 aflatoxin B1 affects expression ISO RGD:1347215 6480464 Aflatoxin B1 affects the expression of TIMP1 protein CTD PMID:20106945 aflatoxin B1 increases methylation ISO RGD:1347215 6480464 Aflatoxin B1 results in increased methylation of TIMP1 intron CTD PMID:30157460 aflatoxin B1 increases expression ISO RGD:1347215 6480464 Aflatoxin B1 results in increased expression of TIMP1 mRNA CTD PMID:21632981 more ... aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of TIMP1 mRNA CTD PMID:14600272 , PMID:15890375 AICA ribonucleotide multiple interactions ISO RGD:1347215 6480464 AICA ribonucleotide inhibits the reaction [TGFB1 protein results in increased expression of TIMP1 protein] CTD PMID:27688165 alachlor increases expression EXP 6480464 alachlor results in increased expression of TIMP1 mRNA CTD PMID:12419858 aldehydo-D-glucosamine multiple interactions EXP 6480464 Glucosamine inhibits the reaction [IL1B results in increased expression of TIMP1 mRNA], IL1B promotes the reaction [Glucosamine results in increased expression of TIMP1 mRNA] CTD PMID:17109745 aldehydo-D-glucosamine increases expression EXP 6480464 Glucosamine results in increased expression of TIMP1 mRNA CTD PMID:17109745 aldehydo-D-glucose increases secretion ISO RGD:1347215 6480464 Glucose deficiency results in increased secretion of TIMP1 protein CTD PMID:24802182 alendronic acid affects expression EXP 6480464 Alendronate affects the expression of TIMP1 mRNA CTD PMID:16079270 all-trans-retinoic acid multiple interactions ISO RGD:1347215 6480464 [Tretinoin co-treated with OSM protein] results in increased expression of TIMP1 mRNA CTD PMID:16467367 all-trans-retinoic acid multiple interactions EXP 6480464 Tretinoin inhibits the reaction [Doxorubicin results in increased expression of TIMP1 mRNA], Tretinoin inhibits the reaction [Doxorubicin results in increased expression of TIMP1 protein] CTD PMID:19357873 all-trans-retinoic acid increases expression ISO RGD:1347215 6480464 Tretinoin results in increased expression of TIMP1 mRNA CTD PMID:15498508 , PMID:16467367 allyl alcohol increases expression EXP 6480464 allyl alcohol results in increased expression of TIMP1 mRNA CTD PMID:23558518 AM-251 multiple interactions ISO RGD:1347215 6480464 [iodopravadoline co-treated with AM 251] inhibits the reaction [Dronabinol results in increased expression of TIMP1 protein] more ... CTD PMID:18159069 aminoguanidine increases expression EXP 6480464 pimagedine results in increased expression of TIMP1 mRNA CTD PMID:18380797 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of TIMP1 mRNA CTD PMID:16483693 Ammothamnine multiple interactions EXP 6480464 oxymatrine inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 protein] CTD PMID:15633229 amphotericin B methyl ester increases expression ISO RGD:731433 6480464 methylamphotericin B results in increased expression of TIMP1 mRNA CTD PMID:22863853 ampicillin decreases expression ISO RGD:1347215 6480464 Ampicillin results in decreased expression of TIMP1 mRNA CTD PMID:21632981 anandamide increases expression ISO RGD:1347215 6480464 anandamide results in increased expression of TIMP1 mRNA CTD PMID:16330497 anandamide multiple interactions ISO RGD:1347215 6480464 N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [anandamide results in increased expression of TIMP1 mRNA] CTD PMID:16330497 anethole increases expression ISO RGD:1347215 6480464 anethole results in increased expression of TIMP1 mRNA CTD PMID:21212515 anthocyanin multiple interactions ISO RGD:731433 6480464 Anthocyanins inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 protein] CTD PMID:30056145 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO RGD:1347215 6480464 pyrazolanthrone inhibits the reaction [thymoquinone results in increased expression of TIMP1 protein] CTD PMID:27060453 antirheumatic drug decreases expression ISO RGD:1347215 6480464 Antirheumatic Agents results in decreased expression of TIMP1 mRNA CTD PMID:24449571 arachidonic acid multiple interactions EXP 6480464 [ferric nitrilotriacetate co-treated with Arachidonic Acid] results in increased expression of TIMP1 mRNA, CYGB protein inhibits the reaction [[ferric nitrilotriacetate co-treated with Arachidonic Acid] results in increased expression of TIMP1 mRNA] CTD PMID:16581302 Arecaidine increases expression ISO RGD:1347215 6480464 arecaidine results in increased expression of TIMP1 mRNA, arecaidine results in increased expression of TIMP1 protein CTD PMID:16311067 arecoline increases expression ISO RGD:1347215 6480464 Arecoline results in increased expression of TIMP1 mRNA, Arecoline results in increased expression of TIMP1 protein CTD PMID:16311067 argatroban multiple interactions ISO RGD:731433 6480464 argatroban inhibits the reaction [Dietary Fats results in increased expression of TIMP1 mRNA] CTD PMID:22841818 arsenic acid multiple interactions ISO RGD:731433 6480464 Dietary Fats promotes the reaction [arsenic acid results in increased expression of TIMP1 mRNA] CTD PMID:18296743 arsenic acid increases expression ISO RGD:731433 6480464 arsenic acid results in increased expression of TIMP1 mRNA CTD PMID:18296743 arsenite(3-) multiple interactions ISO RGD:731433 6480464 Dietary Fats promotes the reaction [arsenite results in increased expression of TIMP1 mRNA] CTD PMID:18296743 arsenite(3-) increases expression EXP 6480464 arsenite results in increased expression of TIMP1 mRNA CTD PMID:18296743 ATP multiple interactions ISO RGD:731433 6480464 azetidine analog inhibits the reaction [Adenosine Triphosphate results in decreased secretion of TIMP1 protein] CTD PMID:26522449 ATP decreases secretion ISO RGD:731433 6480464 Adenosine Triphosphate results in decreased secretion of TIMP1 protein CTD PMID:26522449 Aurothioglucose multiple interactions ISO RGD:731433 6480464 [Dietary Fats co-treated with Aurothioglucose] results in increased expression of TIMP1 protein CTD PMID:21382165 Azaspiracid increases expression EXP 6480464 azaspiracid results in increased expression of TIMP1 protein CTD PMID:26865666 azathioprine increases expression ISO RGD:1347215 6480464 Azathioprine results in increased expression of TIMP1 mRNA CTD PMID:22623647 azetidine multiple interactions ISO RGD:731433 6480464 azetidine analog inhibits the reaction [Adenosine Triphosphate results in decreased secretion of TIMP1 protein] CTD PMID:26522449 bacitracin increases expression EXP 6480464 Bacitracin results in increased expression of TIMP1 mRNA CTD PMID:18289764 beclomethasone increases expression ISO RGD:1347215 6480464 Beclomethasone results in increased expression of TIMP1 protein CTD PMID:10452757 benazepril decreases expression EXP 6480464 benazepril results in decreased expression of TIMP1 mRNA, benazepril results in decreased expression of TIMP1 protein CTD PMID:11867951 , PMID:18471418 benazepril multiple interactions EXP 6480464 benazepril inhibits the reaction [Doxorubicin results in increased expression of TIMP1 mRNA], benazepril inhibits the reaction [Doxorubicin results in increased expression of TIMP1 protein] CTD PMID:19357873 benomyl increases expression ISO RGD:1347215 6480464 Benomyl results in increased expression of TIMP1 mRNA CTD PMID:25530041 benzo[a]pyrene increases expression ISO RGD:731433 6480464 Benzo(a)pyrene results in increased expression of TIMP1 mRNA CTD PMID:22228805 benzo[a]pyrene affects methylation ISO RGD:1347215 6480464 Benzo(a)pyrene affects the methylation of TIMP1 promoter CTD PMID:30157460 benzo[a]pyrene increases expression ISO RGD:1347215 6480464 Benzo(a)pyrene results in increased expression of TIMP1 mRNA CTD PMID:20106945 more ... Benzo[k]fluoranthene increases expression ISO RGD:1347215 6480464 benzo(k)fluoranthene results in increased expression of TIMP1 mRNA CTD PMID:22579512 beta-D-glucosamine multiple interactions EXP 6480464 Glucosamine inhibits the reaction [IL1B results in increased expression of TIMP1 mRNA], IL1B promotes the reaction [Glucosamine results in increased expression of TIMP1 mRNA] CTD PMID:17109745 beta-D-glucosamine increases expression EXP 6480464 Glucosamine results in increased expression of TIMP1 mRNA CTD PMID:17109745 beta-naphthoflavone multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TIMP1 mRNA CTD PMID:18164116 , PMID:20045035 betulin multiple interactions EXP 6480464 betulin inhibits the reaction [Ethanol results in increased expression of TIMP1 protein] CTD PMID:21172400 betulinic acid multiple interactions EXP 6480464 betulinic acid inhibits the reaction [Ethanol results in increased expression of TIMP1 protein] CTD PMID:21172400 bezafibrate multiple interactions ISO RGD:731433 6480464 Bezafibrate inhibits the reaction [[Choline deficiency co-treated with Methionine deficiency] results in increased expression of TIMP1 mRNA] CTD PMID:18513333 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of TIMP1 mRNA CTD PMID:25181051 bisphenol A multiple interactions ISO RGD:1347215 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of TIMP1 mRNA CTD PMID:28628672 Bisphenol A diglycidyl ether multiple interactions EXP 6480464 2, 2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [ursolic acid inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased expression of TIMP1 protein]] CTD PMID:27274199 bleomycin A2 increases expression ISO RGD:731433 6480464 Bleomycin results in increased expression of TIMP1 mRNA, Bleomycin results in increased expression of TIMP1 protein CTD PMID:26345256 , PMID:28300665 bleomycin A2 multiple interactions ISO RGD:731433 6480464 Dexamethasone inhibits the reaction [Bleomycin results in increased expression of TIMP1 protein], Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of TIMP1 protein] CTD PMID:28300665 bromobenzene increases expression EXP 6480464 bromobenzene results in increased expression of TIMP1 mRNA CTD PMID:12628495 , PMID:15056800 budesonide multiple interactions EXP 6480464 Budesonide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TIMP1 mRNA] CTD PMID:15734790 C60 fullerene increases expression ISO RGD:731433 6480464 fullerene C60 results in increased expression of TIMP1 mRNA CTD PMID:20064541 cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of TIMP1 mRNA CTD PMID:25993096 cadmium dichloride multiple interactions EXP 6480464 Curcumin inhibits the reaction [Cadmium Chloride results in increased export of TIMP1 protein] CTD PMID:29421648 cadmium dichloride increases export EXP 6480464 Cadmium Chloride results in increased export of TIMP1 protein CTD PMID:29421648 cadmium dichloride increases secretion EXP 6480464 Cadmium Chloride results in increased secretion of TIMP1 protein CTD PMID:26815315 cadmium dichloride decreases expression ISO RGD:1347215 6480464 Cadmium Chloride results in decreased expression of TIMP1 mRNA CTD PMID:26472689 cadmium sulfate multiple interactions ISO RGD:731433 6480464 cadmium sulfate affects the reaction [MTF1 affects the expression of TIMP1 mRNA] CTD PMID:16221973 calcium dichloride decreases expression ISO RGD:731433 6480464 Calcium Chloride results in decreased expression of TIMP1 mRNA CTD PMID:22728078 calcium dichloride multiple interactions ISO RGD:731433 6480464 Quercetin inhibits the reaction [Calcium Chloride results in decreased expression of TIMP1 mRNA] CTD PMID:22728078 cannabidiol increases expression ISO RGD:1347215 6480464 Cannabidiol results in increased expression of TIMP1 mRNA, Cannabidiol results in increased expression of TIMP1 protein CTD PMID:22198381 cannabidiol multiple interactions ISO RGD:1347215 6480464 ICAM1 mutant form inhibits the reaction [Cannabidiol results in increased expression of TIMP1 protein] CTD PMID:22198381 capsaicin increases expression ISO RGD:1347215 6480464 Capsaicin results in increased expression of TIMP1 mRNA CTD PMID:21310942 capsaicin increases expression EXP 6480464 Capsaicin results in increased expression of TIMP1 protein CTD PMID:22150557 capsaicin multiple interactions EXP 6480464 [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of TIMP1 protein] more ... CTD PMID:22150557 capsazepine multiple interactions ISO RGD:1347215 6480464 capsazepine inhibits the reaction [methanandamide results in increased expression of TIMP1 protein] CTD PMID:18159069 carbendazim increases expression ISO RGD:1347215 6480464 carbendazim results in increased expression of TIMP1 mRNA CTD PMID:25530041 carbofuran increases expression EXP 6480464 Carbofuran results in increased expression of TIMP1 mRNA CTD PMID:20211217 carbon nanotube affects expression ISO RGD:731433 6480464 Nanotubes, Carbon affects the expression of TIMP1 mRNA CTD PMID:23845593 carbon nanotube increases expression ISO RGD:731433 6480464 Nanotubes, Carbon analog results in increased expression of TIMP1 mRNA, Nanotubes, Carbon results in increased expression of TIMP1 mRNA CTD PMID:24664304 , PMID:25554681 carfilzomib multiple interactions EXP 6480464 carfilzomib inhibits the reaction [Diethylnitrosamine results in increased expression of TIMP1 protein] CTD PMID:24632418 carvedilol multiple interactions EXP 6480464 carvedilol inhibits the reaction [Ethanol results in increased expression of TIMP1 mRNA], carvedilol inhibits the reaction [Ethanol results in increased expression of TIMP1 protein] CTD PMID:22413959 carvedilol decreases expression EXP 6480464 carvedilol results in decreased expression of TIMP1 mRNA CTD PMID:21216836 cefaloridine increases expression EXP 6480464 Cephaloridine results in increased expression of TIMP1 mRNA CTD PMID:18500788 chenodeoxycholic acid multiple interactions ISO RGD:731433 6480464 Chenodeoxycholic Acid affects the reaction [alisol A 24-acetate inhibits the reaction [[Choline deficiency co-treated with Methionine deficiency] results in increased expression of TIMP1 mRNA]], Chenodeoxycholic Acid inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA] CTD PMID:27773935 , PMID:29883724 chlordecone multiple interactions ISO RGD:731433 6480464 [Chlordecone co-treated with Carbon Tetrachloride] results in increased expression of TIMP1 mRNA CTD PMID:26853152 chloroform increases expression EXP 6480464 Chloroform results in increased expression of TIMP1 mRNA CTD PMID:17522070 , PMID:23558518 chloropicrin increases expression ISO RGD:1347215 6480464 chloropicrin results in increased expression of TIMP1 mRNA CTD PMID:26352163 choline multiple interactions ISO RGD:731433 6480464 3 more ... CTD PMID:18513333 more ... Chorionic gonadotropin multiple interactions ISO RGD:731433 6480464 [Gonadotropins, Equine co-treated with Chorionic Gonadotropin] results in increased expression of TIMP mRNA CTD PMID:15831568 chromium atom increases expression ISO RGD:1347215 6480464 Chromium results in increased expression of TIMP1 mRNA, Chromium results in increased expression of TIMP1 protein CTD PMID:15878362 , PMID:16581223 chromium atom multiple interactions ISO RGD:1347215 6480464 Genistein inhibits the reaction [Chromium results in increased expression of TIMP1 mRNA] CTD PMID:15878362 chromium(3+) multiple interactions ISO RGD:1347215 6480464 Genistein inhibits the reaction [Chromium results in increased expression of TIMP1 mRNA] CTD PMID:15878362 chromium(3+) increases expression ISO RGD:1347215 6480464 Chromium results in increased expression of TIMP1 mRNA, Chromium results in increased expression of TIMP1 protein CTD PMID:15878362 , PMID:16581223 chrysene increases expression ISO RGD:1347215 6480464 chrysene results in increased expression of TIMP1 mRNA CTD PMID:22579512 cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of TIMP1 mRNA, Cisplatin results in increased expression of TIMP1 protein CTD PMID:18289764 , PMID:23287709 cisplatin increases expression ISO RGD:1347215 6480464 Cisplatin results in increased expression of TIMP1 mRNA, Cisplatin results in increased expression of TIMP1 protein CTD PMID:23287709 cisplatin multiple interactions ISO RGD:1347215 6480464 [Cisplatin co-treated with Paclitaxel] results in increased expression of TIMP1 mRNA CTD PMID:20705681 cisplatin increases expression ISO RGD:731433 6480464 Cisplatin results in increased expression of TIMP1 mRNA CTD PMID:21151649 clodronic acid multiple interactions ISO RGD:731433 6480464 Clodronic Acid inhibits the reaction [PTEN gene mutant form results in increased expression of TIMP1 mRNA] CTD PMID:27022031 cobalt atom increases expression ISO RGD:1347215 6480464 Cobalt results in increased expression of TIMP1 mRNA CTD PMID:15878362 cobalt atom multiple interactions ISO RGD:1347215 6480464 Genistein inhibits the reaction [Cobalt results in increased expression of TIMP1 mRNA] CTD PMID:15878362 cobalt(2+) increases expression ISO RGD:1347215 6480464 Cobalt results in increased expression of TIMP1 mRNA CTD PMID:15878362 cobalt(2+) multiple interactions ISO RGD:1347215 6480464 Genistein inhibits the reaction [Cobalt results in increased expression of TIMP1 mRNA] CTD PMID:15878362 Colforsin dapropate hydrochloride increases expression ISO RGD:731433 6480464 Colforsin results in increased expression of TIMP1 mRNA CTD PMID:20378682 copper atom multiple interactions EXP 6480464 [ATP7B protein affects the susceptibility to Copper] which affects the expression of TIMP1 mRNA, [glycyl-histidyl-lysine co-treated with Copper] results in increased secretion of TIMP1 protein CTD PMID:11045606 , PMID:23112546 copper atom decreases expression EXP 6480464 Copper results in decreased expression of TIMP1 mRNA CTD PMID:30556269 copper(0) multiple interactions EXP 6480464 [ATP7B protein affects the susceptibility to Copper] which affects the expression of TIMP1 mRNA, [glycyl-histidyl-lysine co-treated with Copper] results in increased secretion of TIMP1 protein CTD PMID:11045606 , PMID:23112546 copper(0) decreases expression EXP 6480464 Copper results in decreased expression of TIMP1 mRNA CTD PMID:30556269 copper(2+) multiple interactions EXP 6480464 [ATP7B protein affects the susceptibility to Copper] which affects the expression of TIMP1 mRNA, [glycyl-histidyl-lysine co-treated with Copper] results in increased secretion of TIMP1 protein CTD PMID:11045606 , PMID:23112546 copper(2+) decreases expression EXP 6480464 Copper results in decreased expression of TIMP1 mRNA CTD PMID:30556269 copper(II) sulfate increases expression ISO RGD:1347215 6480464 Copper Sulfate results in increased expression of TIMP1 mRNA CTD PMID:19549813 crocidolite asbestos increases expression ISO RGD:731433 6480464 Asbestos, Crocidolite results in increased expression of TIMP1 CTD PMID:16574944 cucurbitacin E multiple interactions ISO RGD:731433 6480464 cucurbitacin E inhibits the reaction [Thioacetamide results in increased expression of TIMP1 protein] CTD PMID:27363783 cucurbitacin E decreases expression EXP 6480464 cucurbitacin E results in decreased expression of TIMP1 mRNA, cucurbitacin E results in decreased expression of TIMP1 protein CTD PMID:27363783 curcumin multiple interactions ISO RGD:731433 6480464 Curcumin inhibits the reaction [Thioacetamide results in increased expression of TIMP1 protein], Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TIMP1 mRNA] CTD PMID:18200517 , PMID:27363783 curcumin multiple interactions EXP 6480464 Curcumin inhibits the reaction [Cadmium Chloride results in increased export of TIMP1 protein] CTD PMID:29421648 curcumin decreases expression ISO RGD:1347215 6480464 Curcumin results in decreased expression of TIMP1 protein CTD PMID:17996675 cyanuric acid multiple interactions EXP 6480464 [cyanuric acid co-treated with melamine] results in increased expression of TIMP1 mRNA, [melamine co-treated with cyanuric acid] results in increased expression of TIMP1 mRNA CTD PMID:21784140 , PMID:23022069 cycloheximide decreases response to substance EXP 6480464 TIMP1 protein results in decreased susceptibility to Cycloheximide CTD PMID:15860571 cyclophosphamide increases expression EXP 6480464 Cyclophosphamide results in increased expression of TIMP1 mRNA CTD PMID:23558518 cyclosporin A increases expression EXP 6480464 Cyclosporine results in increased expression of TIMP1 mRNA CTD PMID:21865292 , PMID:23558518 cyclosporin A increases expression ISO RGD:1347215 6480464 Cyclosporine results in increased expression of TIMP1 mRNA CTD PMID:10914799 more ... cylindrospermopsin increases expression ISO RGD:1347215 6480464 cylindrospermopsin results in increased expression of TIMP1 mRNA CTD PMID:23726867 cystamine multiple interactions EXP 6480464 Cystamine inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA] CTD PMID:17708605 cytarabine decreases expression ISO RGD:1347215 6480464 Cytarabine results in decreased expression of TIMP1 mRNA CTD PMID:21198554 D-glucosamine multiple interactions EXP 6480464 Glucosamine inhibits the reaction [IL1B results in increased expression of TIMP1 mRNA], IL1B promotes the reaction [Glucosamine results in increased expression of TIMP1 mRNA] CTD PMID:17109745 D-glucosamine increases expression EXP 6480464 Glucosamine results in increased expression of TIMP1 mRNA CTD PMID:17109745 D-glucose increases secretion ISO RGD:1347215 6480464 Glucose deficiency results in increased secretion of TIMP1 protein CTD PMID:24802182 Deguelin increases expression ISO RGD:1347215 6480464 deguelin results in increased expression of TIMP1 protein CTD PMID:25322282 dexamethasone multiple interactions ISO RGD:731433 6480464 [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of TIMP1 mRNA more ... CTD PMID:16054899 , PMID:28300665 dexamethasone multiple interactions ISO RGD:1347215 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of TIMP1 mRNA CTD PMID:28628672 dexamethasone decreases expression ISO RGD:731433 6480464 Dexamethasone results in decreased expression of TIMP1 mRNA CTD PMID:22733784 dexamethasone increases expression EXP 6480464 Dexamethasone results in increased expression of TIMP1 mRNA, Dexamethasone results in increased expression of TIMP1 protein CTD PMID:16718785 dextran sulfate multiple interactions ISO RGD:731433 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TIMP1 mRNA CTD PMID:29950665 diallyl disulfide increases expression ISO RGD:1347215 6480464 diallyl disulfide results in increased expression of TIMP1 mRNA CTD PMID:20600798 diallyl trisulfide increases expression ISO RGD:1347215 6480464 diallyl trisulfide results in increased expression of TIMP1 mRNA, diallyl trisulfide results in increased expression of TIMP1 protein CTD PMID:24084732 dibenz[a,h]anthracene increases expression ISO RGD:1347215 6480464 1 more ... CTD PMID:22579512 dibutyl phthalate decreases expression EXP 6480464 Dibutyl Phthalate results in decreased expression of TIMP1 mRNA CTD PMID:21266533 dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of TIMP1 mRNA CTD PMID:15829613 , PMID:21266533 dichlorine multiple interactions EXP 6480464 [Ozone co-treated with Chlorine] results in decreased expression of TIMP1 mRNA CTD PMID:18636392 diclofenac decreases expression EXP 6480464 Diclofenac results in decreased expression of TIMP1 mRNA CTD PMID:19022234 diclofenac increases expression ISO RGD:731433 6480464 Diclofenac results in increased expression of TIMP1 mRNA CTD PMID:26934552 diethylstilbestrol increases expression EXP 6480464 Diethylstilbestrol results in increased expression of TIMP1 mRNA CTD PMID:15890375 diltiazem multiple interactions EXP 6480464 Diltiazem inhibits the reaction [ferrous sulfate results in increased expression of TIMP1 protein] CTD PMID:27095094 dioxygen multiple interactions EXP 6480464 2 more ... CTD PMID:12882763 more ... dioxygen multiple interactions ISO RGD:731433 6480464 [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of TIMP1 mRNA CTD PMID:30529165 dioxygen increases expression EXP 6480464 Oxygen deficiency results in increased expression of TIMP1 mRNA, Oxygen results in increased expression of TIMP1 mRNA CTD PMID:16980344 , PMID:22911455 diuron decreases expression EXP 6480464 Diuron results in decreased expression of TIMP1 mRNA CTD PMID:25152437 diuron increases expression ISO RGD:1347215 6480464 Diuron metabolite results in increased expression of TIMP1 mRNA CTD PMID:24172598 dopamine increases expression EXP 6480464 Dopamine results in increased expression of TIMP1 mRNA CTD PMID:21983523 doxorubicin decreases expression EXP 6480464 Doxorubicin results in decreased expression of TIMP1 mRNA, Doxorubicin results in decreased expression of TIMP1 protein CTD PMID:20051877 , PMID:30588110 doxorubicin affects expression ISO RGD:1347215 6480464 Doxorubicin affects the expression of TIMP1 mRNA CTD PMID:29803840 doxorubicin increases expression EXP 6480464 Doxorubicin results in increased expression of TIMP1 mRNA, Doxorubicin results in increased expression of TIMP1 protein CTD PMID:19357873 more ... doxorubicin multiple interactions EXP 6480464 [Lisinopril co-treated with GH1 protein] inhibits the reaction [Doxorubicin results in decreased expression of TIMP1 protein] more ... CTD PMID:19357873 more ... ebselen multiple interactions EXP 6480464 ebselen inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA] CTD PMID:11903743 edaravone multiple interactions EXP 6480464 Edaravone inhibits the reaction [Paraquat results in increased expression of TIMP1 mRNA] CTD PMID:21040696 elemental selenium decreases expression ISO RGD:1347215 6480464 Selenium results in decreased expression of TIMP1 mRNA CTD PMID:17390030 elemental selenium multiple interactions ISO RGD:1347215 6480464 Selenium inhibits the reaction [T-2 Toxin results in decreased expression of TIMP1 protein] CTD PMID:21144892 elemental selenium increases expression EXP 6480464 Selenium deficiency results in increased expression of TIMP1 mRNA CTD PMID:11444866 erythromycin estolate increases expression EXP 6480464 Erythromycin Estolate results in increased expression of TIMP1 mRNA CTD PMID:17522070 ethanol multiple interactions ISO RGD:731433 6480464 [Ethanol co-treated with Thioacetamide] results in increased expression of TIMP1 mRNA more ... CTD PMID:16780996 more ... ethanol increases expression ISO RGD:731433 6480464 Ethanol results in increased expression of TIMP1 mRNA, Ethanol results in increased expression of TIMP1 protein CTD PMID:28964808 ethanol increases expression EXP 6480464 Ethanol results in increased expression of TIMP1 mRNA, Ethanol results in increased expression of TIMP1 protein CTD PMID:21172400 more ... ethanol multiple interactions EXP 6480464 8-(4-methoxyphenyl)-4-oxo-4 more ... CTD PMID:21172400 more ... fasudil hydrochloride affects expression ISO RGD:731433 6480464 fasudil affects the expression of TIMP1 mRNA CTD PMID:22465603 fenhexamid increases expression ISO RGD:1347215 6480464 N-(2, 3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of TIMP1 mRNA CTD PMID:25461557 fenofibrate multiple interactions ISO RGD:731433 6480464 Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA] more ... CTD PMID:19593819 , PMID:28871336 fenoldopam increases expression EXP 6480464 Fenoldopam results in increased expression of TIMP1 mRNA CTD PMID:21983523 ferric oxide multiple interactions ISO RGD:731433 6480464 [Magnetite Nanoparticles co-treated with ferric oxide] results in increased expression of TIMP1 mRNA CTD PMID:20540983 Fexofenadine hydrochloride multiple interactions ISO RGD:1347215 6480464 fexofenadine inhibits the reaction [TNF protein results in increased expression of TIMP1 protein] CTD PMID:15663564 flavonoids multiple interactions EXP 6480464 Flavonoids inhibits the reaction [Dimethylnitrosamine results in increased expression of TIMP1 protein] CTD PMID:16270385 flurbiprofen increases expression ISO RGD:1347215 6480464 Flurbiprofen results in increased expression of TIMP1 protein CTD PMID:19501039 flurbiprofen multiple interactions ISO RGD:1347215 6480464 [[Flurbiprofen results in increased expression of TIMP1 protein] which results in decreased expression of MMP9 mRNA] which results in decreased degradation of HPGD protein, [Flurbiprofen results in increased expression of TIMP1 protein] which results in decreased expression of MMP9 mRNA CTD PMID:19501039 folic acid multiple interactions ISO RGD:731433 6480464 [Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of TIMP1 mRNA, [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of TIMP1 mRNA CTD PMID:20938992 , PMID:23439872 folic acid increases expression EXP 6480464 Folic Acid deficiency results in increased expression of TIMP1 mRNA CTD PMID:20406136 formaldehyde increases expression ISO RGD:1347215 6480464 Formaldehyde results in increased expression of TIMP1 mRNA CTD PMID:23649840 fosinopril decreases expression EXP 6480464 Fosinopril results in decreased expression of TIMP1 mRNA, Fosinopril results in decreased expression of TIMP1 protein CTD PMID:21051829 fosinopril multiple interactions EXP 6480464 [Valsartan co-treated with Fosinopril] results in decreased expression of TIMP1 mRNA, [Valsartan co-treated with Fosinopril] results in decreased expression of TIMP1 protein CTD PMID:21051829 fucoidan decreases secretion ISO RGD:1347215 6480464 fucoidan results in decreased secretion of TIMP1 protein CTD PMID:16364234 furan increases expression EXP 6480464 furan results in increased expression of TIMP1 mRNA CTD PMID:15120968 more ... gadodiamide hydrate increases expression ISO RGD:1347215 6480464 gadodiamide results in increased expression of TIMP1 mRNA, gadodiamide results in increased expression of TIMP1 protein CTD PMID:19561517 gadodiamide hydrate increases expression EXP 6480464 gadodiamide results in increased expression of TIMP1 protein CTD PMID:20938346 gadodiamide hydrate multiple interactions ISO RGD:1347215 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [gadodiamide results in increased expression of TIMP1 protein], U 0126 inhibits the reaction [gadodiamide results in increased expression of TIMP1 protein] CTD PMID:19561517 gallic acid multiple interactions EXP 6480464 Gallic Acid inhibits the reaction [ALB modified form results in increased expression of TIMP1 mRNA] CTD PMID:24309158 genistein decreases expression ISO RGD:1347215 6480464 Genistein results in decreased expression of TIMP1 mRNA CTD PMID:15754008 genistein multiple interactions EXP 6480464 Genistein inhibits the reaction [Ethanol results in increased expression of TIMP1 mRNA] CTD PMID:23274713 genistein multiple interactions ISO RGD:1347215 6480464 Genistein inhibits the reaction [Chromium results in increased expression of TIMP1 mRNA] more ... CTD PMID:15878362 gentamycin increases secretion EXP 6480464 Gentamicins results in increased secretion of TIMP1 protein CTD PMID:20816719 gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of TIMP1 mRNA CTD PMID:18289764 gentamycin affects localization EXP 6480464 Gentamicins affects the localization of TIMP1 protein CTD PMID:20118187 glafenine increases expression EXP 6480464 Glafenine results in increased expression of TIMP1 mRNA CTD PMID:24136188 glucose increases secretion ISO RGD:1347215 6480464 Glucose deficiency results in increased secretion of TIMP1 protein CTD PMID:24802182 Gly-His-Lys multiple interactions EXP 6480464 [glycyl-histidyl-lysine co-treated with Copper] results in increased secretion of TIMP1 protein CTD PMID:11045606 graphite increases expression EXP 6480464 Graphite results in increased expression of TIMP1 mRNA CTD PMID:29933104 herbimycin multiple interactions ISO RGD:1347215 6480464 herbimycin inhibits the reaction [Phosphorylcholine analog results in increased expression of TIMP1 mRNA] CTD PMID:15878362 Hexachloro-1,3-butadiene decreases expression EXP 6480464 hexachlorobutadiene results in decreased expression of TIMP1 mRNA CTD PMID:21905055 Hexachloro-1,3-butadiene increases expression EXP 6480464 hexachlorobutadiene results in increased expression of TIMP1 mRNA, hexachlorobutadiene results in increased expression of TIMP1 protein CTD PMID:21259293 , PMID:21905055 hexachlorobenzene increases expression EXP 6480464 Hexachlorobenzene results in increased expression of TIMP1 mRNA CTD PMID:15159207 hexadecanoic acid multiple interactions ISO RGD:1347215 6480464 [Oleic Acid co-treated with Palmitic Acid] results in increased expression of TIMP1 mRNA, [Palmitic Acid co-treated with Oleic Acid] affects the expression of TIMP1 mRNA CTD PMID:26187275 , PMID:30547786 homocysteine multiple interactions EXP 6480464 Dizocilpine Maleate inhibits the reaction [Homocysteine analog results in increased expression of TIMP1 mRNA], Dizocilpine Maleate inhibits the reaction [Homocysteine analog results in increased expression of TIMP1 protein] CTD PMID:20406136 homocysteine increases expression EXP 6480464 Homocysteine analog results in increased expression of TIMP1 mRNA, Homocysteine analog results in increased expression of TIMP1 protein CTD PMID:20406136 hydrogen peroxide multiple interactions EXP 6480464 Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of TIMP1 protein], tetramethylpyrazine inhibits the reaction [Hydrogen Peroxide results in increased expression of TIMP1 protein] CTD PMID:20881940 , PMID:23022513 hydrogen peroxide increases expression EXP 6480464 Hydrogen Peroxide results in increased expression of TIMP1 protein CTD PMID:20881940 , PMID:23022513 ilomastat multiple interactions EXP 6480464 ilomastat affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TIMP1 mRNA], ilomastat affects the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TIMP1 protein] CTD PMID:18837084 imiquimod increases expression ISO RGD:731433 6480464 imiquimod results in increased expression of TIMP1 protein CTD PMID:14708627 Indeno[1,2,3-cd]pyrene increases expression ISO RGD:1347215 6480464 indeno(1 more ... CTD PMID:22579512 Indeno[1,2,3-cd]pyrene decreases expression ISO RGD:731433 6480464 indeno(1 more ... CTD PMID:26377693 indometacin increases expression ISO RGD:1347215 6480464 Indomethacin results in increased expression of TIMP1 protein CTD PMID:11719597 indometacin multiple interactions ISO RGD:1347215 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of TIMP1 mRNA CTD PMID:28628672 iron(2+) sulfate (anhydrous) increases expression EXP 6480464 ferrous sulfate results in increased expression of TIMP1 protein CTD PMID:27095094 iron(2+) sulfate (anhydrous) multiple interactions EXP 6480464 Diltiazem inhibits the reaction [ferrous sulfate results in increased expression of TIMP1 protein] more ... CTD PMID:27095094 iron(III) nitrilotriacetate multiple interactions EXP 6480464 [ferric nitrilotriacetate co-treated with Arachidonic Acid] results in increased expression of TIMP1 mRNA, CYGB protein inhibits the reaction [[ferric nitrilotriacetate co-treated with Arachidonic Acid] results in increased expression of TIMP1 mRNA] CTD PMID:16581302 isocyanuric acid multiple interactions EXP 6480464 [cyanuric acid co-treated with melamine] results in increased expression of TIMP1 mRNA, [melamine co-treated with cyanuric acid] results in increased expression of TIMP1 mRNA CTD PMID:21784140 , PMID:23022069 isoprenaline increases expression ISO RGD:731433 6480464 Isoproterenol results in increased expression of TIMP1 mRNA CTD PMID:20003209 isoprenaline decreases expression ISO RGD:1347215 6480464 Isoproterenol results in decreased expression of TIMP1 mRNA CTD PMID:24286936 isoprenaline increases expression EXP 6480464 Isoproterenol results in increased expression of TIMP1 mRNA, Isoproterenol results in increased expression of TIMP1 protein CTD PMID:20211217 more ... juglone multiple interactions ISO RGD:1347215 6480464 [juglone co-treated with Ascorbic Acid] affects the expression of TIMP1 mRNA CTD PMID:29992683 ketoconazole decreases expression EXP 6480464 Ketoconazole results in decreased expression of TIMP1 mRNA CTD PMID:18289764 L-ascorbic acid increases expression ISO RGD:1347215 6480464 Ascorbic Acid results in increased expression of TIMP1 protein CTD PMID:12510807 L-ascorbic acid multiple interactions ISO RGD:1347215 6480464 [Ascorbic Acid co-treated with Quartz] results in increased expression of TIMP1 mRNA, [juglone co-treated with Ascorbic Acid] affects the expression of TIMP1 mRNA CTD PMID:27381660 , PMID:29992683 L-ascorbic acid multiple interactions EXP 6480464 Ascorbic Acid inhibits the reaction [AGT protein modified form results in increased expression of TIMP1 protein], Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of TIMP1 protein] CTD PMID:20881940 L-ascorbic acid increases expression EXP 6480464 Ascorbic Acid results in increased expression of TIMP1 mRNA CTD PMID:15372504 L-cysteine multiple interactions EXP 6480464 Cysteine inhibits the reaction [Thioacetamide results in increased expression of TIMP1 mRNA] CTD PMID:15158331 L-methionine multiple interactions ISO RGD:731433 6480464 3 more ... CTD PMID:18513333 more ... L-methionine multiple interactions EXP 6480464 Methionine inhibits the reaction [Thioacetamide results in increased expression of TIMP1 mRNA] CTD PMID:15158331 lamivudine decreases expression ISO RGD:1347215 6480464 Lamivudine results in decreased expression of TIMP1 protein CTD PMID:15309715 lipopolysaccharide increases expression ISO RGD:731433 6480464 Lipopolysaccharides results in increased expression of TIMP1 mRNA, Lipopolysaccharides results in increased expression of TIMP1 protein CTD PMID:19133137 more ... lipopolysaccharide multiple interactions ISO RGD:731433 6480464 terameprocol inhibits the reaction [Lipopolysaccharides results in increased expression of TIMP1 protein] CTD PMID:19133137 lisinopril dihydrate multiple interactions EXP 6480464 [Lisinopril co-treated with GH1 protein] inhibits the reaction [Doxorubicin results in decreased expression of TIMP1 protein], Lisinopril inhibits the reaction [Doxorubicin results in decreased expression of TIMP1 protein] CTD PMID:20051877 lithocholic acid increases expression ISO RGD:731433 6480464 Lithocholic Acid results in increased expression of TIMP1 mRNA CTD PMID:16436656 lornoxicam increases expression EXP 6480464 lornoxicam results in increased expression of TIMP1 mRNA CTD PMID:23142791 losartan multiple interactions EXP 6480464 Losartan inhibits the reaction [Paraquat results in increased expression of TIMP1 mRNA] more ... CTD PMID:20137537 , PMID:25233898 losartan decreases expression EXP 6480464 Losartan results in decreased expression of TIMP1 mRNA CTD PMID:20137537 LY294002 multiple interactions ISO RGD:1347215 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [gadodiamide results in increased expression of TIMP1 protein] CTD PMID:19561517 Meclizine affects expression ISO RGD:1347215 6480464 Meclizine affects the expression of TIMP1 protein CTD PMID:12388792 megestrol affects expression ISO RGD:1347215 6480464 Megestrol affects the expression of TIMP1 protein CTD PMID:12388792 melamine multiple interactions EXP 6480464 [cyanuric acid co-treated with melamine] results in increased expression of TIMP1 mRNA, [melamine co-treated with cyanuric acid] results in increased expression of TIMP1 mRNA CTD PMID:21784140 , PMID:23022069 mercury dichloride increases expression EXP 6480464 Mercuric Chloride results in increased expression of TIMP1 mRNA CTD PMID:11817102 metaproterenol increases expression EXP 6480464 Metaproterenol results in increased expression of TIMP1 mRNA CTD PMID:23558518 methamphetamine increases expression EXP 6480464 Methamphetamine results in increased expression of TIMP1 mRNA CTD PMID:19564919 methapyrilene increases expression EXP 6480464 Methapyrilene results in increased expression of TIMP1 mRNA CTD PMID:15890375 Methazolamide affects expression ISO RGD:1347215 6480464 Methazolamide affects the expression of TIMP1 protein CTD PMID:12388792 methylmercury chloride increases expression ISO RGD:1347215 6480464 methylmercuric chloride results in increased expression of TIMP1 mRNA CTD PMID:28001369 methylmercury chloride increases expression EXP 6480464 methylmercuric chloride results in increased expression of TIMP1 protein CTD PMID:28526320 mifepristone multiple interactions EXP 6480464 Mifepristone inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased expression of TIMP1 protein] CTD PMID:30229846 milrinone increases expression EXP 6480464 Milrinone results in increased expression of TIMP1 mRNA CTD PMID:22936366 mitoxantrone increases expression EXP 6480464 Mitoxantrone results in increased expression of TIMP1 mRNA CTD PMID:23558518 mono(2-ethylhexyl) phthalate decreases expression ISO RGD:731433 6480464 mono-(2-ethylhexyl)phthalate results in decreased expression of TIMP1 mRNA CTD PMID:22401849 mono(2-ethylhexyl) phthalate increases expression ISO RGD:1347215 6480464 mono-(2-ethylhexyl)phthalate results in increased expression of TIMP1 protein CTD PMID:28416457 mono(2-ethylhexyl) phthalate multiple interactions ISO RGD:1347215 6480464 2-chloro-5-nitrobenzanilide inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of TIMP1 protein] more ... CTD PMID:28416457 monocrotaline increases expression EXP 6480464 Monocrotaline results in increased expression of TIMP1 mRNA CTD PMID:22022327 monocrotaline multiple interactions EXP 6480464 Simvastatin inhibits the reaction [Monocrotaline results in increased expression of TIMP1 mRNA] CTD PMID:22022327 N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2-ylidene)acetamide affects expression ISO RGD:1347215 6480464 Methazolamide affects the expression of TIMP1 protein CTD PMID:12388792 N-acetyl-1,4-benzoquinone imine increases expression ISO RGD:1347215 6480464 N-acetyl-4-benzoquinoneimine results in increased expression of TIMP1 mRNA CTD PMID:28286204 N-methyl-4-phenylpyridinium decreases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of TIMP1 mRNA CTD PMID:28801915 N-methyl-4-phenylpyridinium increases methylation EXP 6480464 1-Methyl-4-phenylpyridinium results in increased methylation of TIMP1 gene CTD PMID:28801915 N-methyl-N-nitrosourea increases expression EXP 6480464 Methylnitrosourea results in increased expression of TIMP1 mRNA CTD PMID:17412507 N-nitrosodiethylamine increases expression ISO RGD:1347215 6480464 Diethylnitrosamine results in increased expression of TIMP1 mRNA CTD PMID:21527772 N-nitrosodiethylamine decreases expression ISO RGD:731433 6480464 Diethylnitrosamine results in decreased expression of TIMP1 mRNA CTD PMID:23288052 N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TIMP1 mRNA more ... CTD PMID:18164116 more ... N-nitrosodiethylamine increases expression EXP 6480464 Diethylnitrosamine results in increased expression of TIMP1 mRNA, Diethylnitrosamine results in increased expression of TIMP1 protein CTD PMID:18665156 , PMID:24632418 N-nitrosodimethylamine increases expression EXP 6480464 Dimethylnitrosamine results in increased expression of TIMP1 mRNA, Dimethylnitrosamine results in increased expression of TIMP1 protein CTD PMID:14600272 more ... N-nitrosodimethylamine multiple interactions EXP 6480464 2-phenyl-4-(3-pyridin-2-yl-1H-pyrazol-4-yl)pyridine inhibits the reaction [Dimethylnitrosamine results in increased expression of TIMP1 mRNA] more ... CTD PMID:15339415 more ... N-nitrosodimethylamine multiple interactions ISO RGD:731433 6480464 bicyclol inhibits the reaction [Dimethylnitrosamine results in increased expression of TIMP1 mRNA] CTD PMID:16603200 N-nitrosodimethylamine increases expression ISO RGD:731433 6480464 Dimethylnitrosamine results in increased expression of TIMP1 mRNA CTD PMID:16603200 N-nitrosodimethylamine increases expression ISO RGD:1347215 6480464 Dimethylnitrosamine results in increased expression of TIMP1 mRNA CTD PMID:17547211 N-nitrosomorpholine increases expression EXP 6480464 N-nitrosomorpholine results in increased expression of TIMP1 mRNA CTD PMID:19716841 naloxone increases expression EXP 6480464 Naloxone results in increased expression of TIMP1 mRNA CTD PMID:17522070 naphthalene increases expression ISO RGD:1347215 6480464 naphthalene results in increased expression of TIMP1 mRNA CTD PMID:22579512 naphthalene increases expression ISO RGD:731433 6480464 naphthalene results in increased expression of TIMP1 mRNA CTD PMID:18978301 naproxen multiple interactions EXP 6480464 [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of TIMP1 protein], Naproxen inhibits the reaction [Capsaicin results in increased expression of TIMP1 protein] CTD PMID:22150557 naringin multiple interactions ISO RGD:731433 6480464 naringin inhibits the reaction [Paraquat results in increased expression of TIMP1 mRNA], naringin inhibits the reaction [Paraquat results in increased expression of TIMP1 protein] CTD PMID:23603004 Natamycin increases expression ISO RGD:731433 6480464 Natamycin results in increased expression of TIMP1 mRNA CTD PMID:22863853 nickel atom increases expression ISO RGD:1347215 6480464 Nickel results in increased expression of TIMP1, Nickel results in increased expression of TIMP1 mRNA CTD PMID:21401309 more ... nickel sulfate increases expression EXP 6480464 nickel sulfate results in increased expression of TIMP1 mRNA CTD PMID:11114790 nickel sulfate increases expression ISO RGD:731433 6480464 nickel sulfate results in increased expression of TIMP1 mRNA CTD PMID:16100012 nickel sulfate increases expression ISO RGD:1347215 6480464 nickel sulfate results in increased expression of TIMP1 mRNA CTD PMID:16780908 nicotine multiple interactions ISO RGD:1347215 6480464 [Nicotine co-treated with lipopolysaccharide, E. coli O26-B6] affects the expression of TIMP1 mRNA CTD PMID:18986645 nicotine affects expression ISO RGD:1347215 6480464 Nicotine affects the expression of TIMP1 mRNA CTD PMID:18986645 nimodipine multiple interactions EXP 6480464 Nimodipine inhibits the reaction [ferrous sulfate results in increased expression of TIMP1 protein] CTD PMID:27095094 NS-398 multiple interactions ISO RGD:1347215 6480464 N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [anandamide results in increased expression of TIMP1 mRNA] more ... CTD PMID:16330497 nystatin increases expression ISO RGD:731433 6480464 Nystatin results in increased expression of TIMP1 mRNA CTD PMID:22863853 obeticholic acid multiple interactions EXP 6480464 NR0B2 protein affects the reaction [obeticholic acid inhibits the reaction [JUND protein binds to TIMP1 promoter]] more ... CTD PMID:15860571 obeticholic acid decreases expression ISO RGD:1347215 6480464 obeticholic acid results in decreased expression of TIMP1 mRNA CTD PMID:27939613 ochratoxin A increases expression EXP 6480464 ochratoxin A results in increased expression of TIMP1 mRNA, ochratoxin A results in increased expression of TIMP1 protein CTD PMID:16622519 , PMID:18308701 oleanolic acid multiple interactions ISO RGD:731433 6480464 Oleanolic Acid analog inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA] CTD PMID:17922224 oleic acid multiple interactions ISO RGD:1347215 6480464 [Oleic Acid co-treated with Palmitic Acid] results in increased expression of TIMP1 mRNA, [Palmitic Acid co-treated with Oleic Acid] affects the expression of TIMP1 mRNA CTD PMID:26187275 , PMID:30547786 orciprenaline increases expression EXP 6480464 Metaproterenol results in increased expression of TIMP1 mRNA CTD PMID:23558518 oxaliplatin increases expression EXP 6480464 oxaliplatin results in increased expression of TIMP1 mRNA CTD PMID:25729387 oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of TIMP1 mRNA CTD PMID:25729387 ozone multiple interactions ISO RGD:731433 6480464 [NOTCH3 gene mutant form affects the susceptibility to Ozone] which results in increased expression of TIMP1 mRNA, TTPA protein affects the reaction [Ozone results in increased expression of TIMP1 mRNA] CTD PMID:19555225 , PMID:25658374 ozone increases expression ISO RGD:731433 6480464 Ozone results in increased expression of TIMP1 mRNA CTD PMID:12763052 more ... ozone multiple interactions EXP 6480464 [Ozone co-treated with Chlorine] results in decreased expression of TIMP1 mRNA CTD PMID:18636392 p-menthan-3-ol multiple interactions EXP 6480464 [Tobacco Smoke Pollution co-treated with Menthol] results in increased expression of and results in increased secretion of TIMP1 protein CTD PMID:27818348 paclitaxel multiple interactions ISO RGD:1347215 6480464 [Cisplatin co-treated with Paclitaxel] results in increased expression of TIMP1 mRNA CTD PMID:20705681 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of TIMP1 protein CTD PMID:16687475 paracetamol multiple interactions ISO RGD:731433 6480464 EGR1 protein affects the reaction [Acetaminophen results in increased expression of TIMP1 mRNA] CTD PMID:28286204 paracetamol increases expression ISO RGD:731433 6480464 Acetaminophen results in increased expression of TIMP1 mRNA CTD PMID:28286204 paracetamol increases expression ISO RGD:1347215 6480464 Acetaminophen results in increased expression of TIMP1 mRNA CTD PMID:22230336 paracetamol affects expression ISO RGD:731433 6480464 Acetaminophen affects the expression of TIMP1 mRNA CTD PMID:17562736 paraquat multiple interactions EXP 6480464 [Paraquat co-treated with Oxygen] results in increased expression of TIMP1 mRNA more ... CTD PMID:12882763 more ... paraquat decreases expression ISO RGD:731433 6480464 Paraquat results in decreased expression of TIMP1 protein CTD PMID:26988026 paraquat multiple interactions ISO RGD:1347215 6480464 [CCN2 protein co-treated with Paraquat] affects the expression of TIMP1 mRNA CTD PMID:26129822 paraquat increases expression ISO RGD:731433 6480464 Paraquat results in increased expression of TIMP1 mRNA, Paraquat results in increased expression of TIMP1 protein CTD PMID:17215068 more ... paraquat increases expression EXP 6480464 Paraquat results in increased expression of TIMP1 mRNA CTD PMID:19272247 more ... paraquat multiple interactions ISO RGD:731433 6480464 ADIPOQ protein inhibits the reaction [Paraquat results in increased expression of TIMP1 protein] more ... CTD PMID:23603004 , PMID:25945502 paraquat decreases expression EXP 6480464 Paraquat results in decreased expression of TIMP1 mRNA CTD PMID:18198484 pentane-2,3-dione increases expression EXP 6480464 2, 3-pentanedione results in increased expression of TIMP1 mRNA CTD PMID:25710175 Pentoxifylline increases expression EXP 6480464 Pentoxifylline results in increased expression of TIMP1 mRNA CTD PMID:11788567 perfluorooctanoic acid multiple interactions ISO RGD:731433 6480464 perfluorooctanoic acid promotes the reaction [Dietary Fats results in increased expression of TIMP1 mRNA] CTD PMID:30711707 phenanthrene increases expression ISO RGD:1347215 6480464 phenanthrene results in increased expression of TIMP1 mRNA CTD PMID:22579512 phenobarbital increases expression EXP 6480464 Phenobarbital results in increased expression of TIMP1 mRNA CTD PMID:19162173 phenylephrine multiple interactions EXP 6480464 BCL2 protein affects the reaction [Phenylephrine results in increased expression of TIMP1 protein] more ... CTD PMID:19910689 phenylephrine increases expression EXP 6480464 Phenylephrine results in increased expression of TIMP1 mRNA, Phenylephrine results in increased expression of TIMP1 protein CTD PMID:18158353 , PMID:19910689 phenytoin increases expression ISO RGD:1347215 6480464 Phenytoin results in increased expression of TIMP1 mRNA, Phenytoin results in increased expression of TIMP1 protein CTD PMID:10914799 more ... PhIP multiple interactions EXP 6480464 [2-amino-1-methyl-6-phenylimidazo(4, 5-b)pyridine co-treated with Dietary Fats] results in decreased expression of TIMP1 mRNA CTD PMID:12097258 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:1347215 6480464 Quercetin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TIMP1 mRNA], troglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TIMP1 mRNA] CTD PMID:11414687 , PMID:18155510 phorbol 13-acetate 12-myristate increases expression ISO RGD:1347215 6480464 Tetradecanoylphorbol Acetate results in increased expression of TIMP1 mRNA CTD PMID:11414687 more ... phosgene affects expression ISO RGD:731433 6480464 Phosgene affects the expression of TIMP1 mRNA CTD PMID:16300373 phosphatidylcholine multiple interactions EXP 6480464 [silybin co-treated with Phosphatidylcholines co-treated with Vitamin E] inhibits the reaction [Dimethylnitrosamine results in increased expression of TIMP1 mRNA] CTD PMID:16169303 phosphocholine multiple interactions ISO RGD:1347215 6480464 Genistein inhibits the reaction [Phosphorylcholine analog results in increased expression of TIMP1 mRNA], herbimycin inhibits the reaction [Phosphorylcholine analog results in increased expression of TIMP1 mRNA] CTD PMID:15878362 phosphocholine increases expression ISO RGD:1347215 6480464 Phosphorylcholine analog results in increased expression of TIMP1 mRNA CTD PMID:15878362 phosphorylcholine chloride multiple interactions ISO RGD:1347215 6480464 Genistein inhibits the reaction [Phosphorylcholine analog results in increased expression of TIMP1 mRNA], herbimycin inhibits the reaction [Phosphorylcholine analog results in increased expression of TIMP1 mRNA] CTD PMID:15878362 phosphorylcholine chloride increases expression ISO RGD:1347215 6480464 Phosphorylcholine analog results in increased expression of TIMP1 mRNA CTD PMID:15878362 phthalaldehyde affects expression ISO RGD:731433 6480464 o-Phthalaldehyde affects the expression of TIMP1 mRNA CTD PMID:22302311 pioglitazone multiple interactions EXP 6480464 pioglitazone affects the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA] CTD PMID:16484506 piperonyl butoxide increases expression EXP 6480464 Piperonyl Butoxide results in increased expression of TIMP1 mRNA CTD PMID:15890375 pirfenidone multiple interactions EXP 6480464 pirfenidone inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA] more ... CTD PMID:12445421 more ... pirinixic acid multiple interactions ISO RGD:731433 6480464 pirinixic acid inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA] CTD PMID:19593819 pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of TIMP1 mRNA CTD PMID:15890375 pirinixic acid increases expression ISO RGD:731433 6480464 pirinixic acid results in increased expression of TIMP1 mRNA CTD PMID:20813756 poly(I:C) increases expression ISO RGD:731433 6480464 Poly I-C results in increased expression of TIMP1 mRNA CTD PMID:21195166 pravastatin decreases expression EXP 6480464 Pravastatin results in decreased expression of TIMP1 mRNA CTD PMID:16935385 prednisolone multiple interactions EXP 6480464 pirfenidone promotes the reaction [Prednisolone inhibits the reaction [Paraquat results in increased expression of TIMP1 mRNA]], Prednisolone inhibits the reaction [Paraquat results in increased expression of TIMP1 mRNA] CTD PMID:28921394 Pristimerin multiple interactions EXP 6480464 pristimerin inhibits the reaction [Doxorubicin results in decreased expression of TIMP1 mRNA], pristimerin inhibits the reaction [Doxorubicin results in decreased expression of TIMP1 protein] CTD PMID:30588110 progesterone multiple interactions ISO RGD:1347215 6480464 [Progesterone co-treated with Estradiol] results in increased expression of TIMP1 mRNA CTD PMID:20226447 progesterone increases expression ISO RGD:1347215 6480464 Progesterone results in increased expression of TIMP1 mRNA CTD PMID:20226447 prostaglandin E1 decreases expression EXP 6480464 Alprostadil results in decreased expression of TIMP1 CTD PMID:16859129 prostaglandin E2 increases expression ISO RGD:1347215 6480464 Dinoprostone results in increased expression of TIMP1 mRNA, Dinoprostone results in increased expression of TIMP1 protein CTD PMID:16330497 prostaglandin E2 multiple interactions ISO RGD:731433 6480464 Dinoprostone inhibits the reaction [PTGS1 gene mutant form inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 protein]] CTD PMID:25432964 prostaglandin F2alpha decreases expression ISO RGD:1347215 6480464 Dinoprost results in decreased expression of TIMP1 protein CTD PMID:11719597 puerarin multiple interactions EXP 6480464 puerarin inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA] CTD PMID:23500774 pyrrolidine dithiocarbamate multiple interactions EXP 6480464 pyrrolidine dithiocarbamic acid inhibits the reaction [Paraquat results in increased expression of TIMP1 mRNA], pyrrolidine dithiocarbamic acid inhibits the reaction [Tacrolimus results in increased expression of TIMP1 mRNA] CTD PMID:12472797 , PMID:19272247 quartz multiple interactions ISO RGD:1347215 6480464 [Ascorbic Acid co-treated with Quartz] results in increased expression of TIMP1 mRNA CTD PMID:27381660 quercetin multiple interactions ISO RGD:1347215 6480464 Quercetin promotes the reaction [Cholesterol, LDL results in increased expression of TIMP1 mRNA], Quercetin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TIMP1 mRNA] CTD PMID:11414687 quercetin multiple interactions EXP 6480464 [Quercetin co-treated with Carbon Tetrachloride] results in increased expression of TIMP1 mRNA CTD PMID:22989100 quercetin multiple interactions ISO RGD:731433 6480464 Quercetin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TIMP1 mRNA], Quercetin inhibits the reaction [Calcium Chloride results in decreased expression of TIMP1 mRNA] CTD PMID:22728078 , PMID:22915297 quercetin increases expression ISO RGD:1347215 6480464 Quercetin results in increased expression of TIMP1 mRNA, Quercetin results in increased expression of TIMP1 protein CTD PMID:11414687 , PMID:21632981 quercetin decreases expression ISO RGD:1347215 6480464 Quercetin results in decreased expression of TIMP1 mRNA, Quercetin results in decreased expression of TIMP1 protein CTD PMID:11506819 quercetin 3-O-beta-D-glucofuranoside increases expression ISO RGD:1347215 6480464 isoquercitrin results in increased expression of TIMP1 protein CTD PMID:18715546 quercetin 3-O-beta-D-glucopyranoside increases expression ISO RGD:1347215 6480464 isoquercitrin results in increased expression of TIMP1 protein CTD PMID:18715546 quinidine increases expression EXP 6480464 Quinidine results in increased expression of TIMP1 mRNA CTD PMID:17522070 raloxifene increases expression ISO RGD:1347215 6480464 Raloxifene Hydrochloride results in increased expression of TIMP1 mRNA CTD PMID:16202921 raloxifene affects expression EXP 6480464 Raloxifene Hydrochloride affects the expression of TIMP1 mRNA CTD PMID:16079270 razoxane multiple interactions EXP 6480464 Razoxane inhibits the reaction [Doxorubicin results in increased expression of TIMP1 mRNA] CTD PMID:19915844 resveratrol multiple interactions EXP 6480464 [resveratrol co-treated with Streptozocin] results in increased expression of TIMP1 mRNA, resveratrol affects the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TIMP1 mRNA] CTD PMID:15734790 , PMID:25905778 resveratrol decreases expression ISO RGD:1347215 6480464 resveratrol results in decreased expression of TIMP1 protein CTD PMID:25128170 resveratrol increases expression EXP 6480464 resveratrol results in increased expression of TIMP1 mRNA CTD PMID:25905778 resveratrol decreases expression ISO RGD:731433 6480464 resveratrol results in decreased expression of TIMP1 mRNA CTD PMID:22086758 , PMID:25394648 rotenone increases expression ISO RGD:1347215 6480464 Rotenone results in increased expression of TIMP1 mRNA CTD PMID:29955902 SB 203580 multiple interactions ISO RGD:1347215 6480464 SB 203580 inhibits the reaction [Dronabinol results in increased expression of TIMP1 protein] more ... CTD PMID:18159069 , PMID:27060453 selenium atom decreases expression ISO RGD:1347215 6480464 Selenium results in decreased expression of TIMP1 mRNA CTD PMID:17390030 selenium atom multiple interactions ISO RGD:1347215 6480464 Selenium inhibits the reaction [T-2 Toxin results in decreased expression of TIMP1 protein] CTD PMID:21144892 selenium atom increases expression EXP 6480464 Selenium deficiency results in increased expression of TIMP1 mRNA CTD PMID:11444866 serpentine asbestos multiple interactions ISO RGD:731433 6480464 SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in increased expression of TIMP1 mRNA], U 0126 inhibits the reaction [Asbestos, Serpentine results in increased expression of TIMP1 mRNA] CTD PMID:16571779 , PMID:21514415 serpentine asbestos increases expression ISO RGD:731433 6480464 Asbestos, Serpentine results in increased expression of TIMP1 mRNA CTD PMID:16571779 , PMID:21514415 silicon dioxide affects secretion ISO RGD:1347215 6480464 Silicon Dioxide analog affects the secretion of TIMP1 protein CTD PMID:25895662 silicon dioxide multiple interactions ISO RGD:731433 6480464 [SOD3 gene mutant form results in increased susceptibility to Silicon Dioxide] which results in increased expression of TIMP1 mRNA CTD PMID:30453980 silicon dioxide increases expression ISO RGD:731433 6480464 Silicon Dioxide results in increased expression of TIMP1 mRNA, Silicon Dioxide results in increased expression of TIMP1 protein CTD PMID:23221170 more ... simvastatin multiple interactions EXP 6480464 Losartan inhibits the reaction [Simvastatin results in decreased expression of TIMP1 mRNA] more ... CTD PMID:20137537 , PMID:22022327 simvastatin decreases expression EXP 6480464 Simvastatin results in decreased expression of TIMP1 mRNA CTD PMID:16414398 , PMID:20137537 sodium arsenite increases expression ISO RGD:731433 6480464 sodium arsenite results in increased expression of TIMP1 mRNA CTD PMID:21134390 sodium dichromate increases expression EXP 6480464 sodium bichromate results in increased expression of TIMP1 mRNA CTD PMID:25993096 Solasodine increases expression ISO RGD:1347215 6480464 solasodine results in increased expression of TIMP1 mRNA CTD PMID:28283413 streptozocin increases activity EXP 6480464 Streptozocin results in increased activity of TIMP1 protein CTD PMID:25246140 streptozocin increases expression EXP 6480464 Streptozocin results in increased expression of TIMP1 mRNA CTD PMID:18246672 streptozocin multiple interactions EXP 6480464 [resveratrol co-treated with Streptozocin] results in increased expression of TIMP1 mRNA, Olive Oil promotes the reaction [Streptozocin results in increased activity of TIMP1 protein] CTD PMID:25246140 , PMID:25905778 sulfasalazine multiple interactions EXP 6480464 Sulfasalazine inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 protein] CTD PMID:15633128 sulforaphane increases expression ISO RGD:1347215 6480464 sulforafan results in increased expression of TIMP1 mRNA CTD PMID:26833863 sulindac affects expression ISO RGD:1347215 6480464 Sulindac affects the expression of TIMP1 protein CTD PMID:12388792 sumatriptan multiple interactions EXP 6480464 [Naproxen co-treated with Sumatriptan] inhibits the reaction [Capsaicin results in increased expression of TIMP1 protein], Sumatriptan inhibits the reaction [Capsaicin results in increased expression of TIMP1 protein] CTD PMID:22150557 sunitinib multiple interactions EXP 6480464 Carnitine inhibits the reaction [sunitinib results in increased expression of TIMP1 mRNA] CTD PMID:26581635 sunitinib increases expression EXP 6480464 sunitinib results in increased expression of TIMP1 mRNA CTD PMID:26581635 T-2 Toxin decreases expression ISO RGD:1347215 6480464 T-2 Toxin results in decreased expression of TIMP1 protein CTD PMID:21144892 T-2 Toxin affects expression ISO RGD:731433 6480464 T-2 Toxin affects the expression of TIMP1 mRNA CTD PMID:21112371 T-2 Toxin multiple interactions ISO RGD:1347215 6480464 Selenium inhibits the reaction [T-2 Toxin results in decreased expression of TIMP1 protein] CTD PMID:21144892 tacrolimus hydrate multiple interactions EXP 6480464 pirfenidone promotes the reaction [Tacrolimus results in decreased expression of TIMP1 mRNA], pyrrolidine dithiocarbamic acid inhibits the reaction [Tacrolimus results in increased expression of TIMP1 mRNA] CTD PMID:12472797 , PMID:15854665 tacrolimus hydrate decreases expression EXP 6480464 Tacrolimus results in decreased expression of TIMP1 mRNA CTD PMID:11091246 , PMID:15854665 tacrolimus hydrate increases expression EXP 6480464 Tacrolimus results in increased expression of TIMP1 mRNA CTD PMID:12472797 , PMID:21865292 tamibarotene increases expression ISO RGD:1347215 6480464 tamibarotene results in increased expression of TIMP1 mRNA CTD PMID:15498508 tebuconazole increases expression ISO RGD:1347215 6480464 tebuconazole results in increased expression of TIMP1 mRNA CTD PMID:26852204 Tesaglitazar decreases expression EXP 6480464 tesaglitazar results in decreased expression of TIMP1 mRNA CTD PMID:21515302 tetrachloromethane affects expression ISO RGD:731433 6480464 Carbon Tetrachloride affects the expression of TIMP1 mRNA CTD PMID:17484886 tetrachloromethane multiple interactions EXP 6480464 [Carbon Tetrachloride co-treated with Ethanol] results in increased expression of TIMP1 mRNA more ... CTD PMID:11903743 more ... tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of TIMP1 mRNA, Carbon Tetrachloride results in increased expression of TIMP1 protein CTD PMID:11903743 more ... tetrachloromethane decreases expression ISO RGD:731433 6480464 Carbon Tetrachloride results in decreased expression of TIMP1 mRNA CTD PMID:25827057 tetrachloromethane increases expression ISO RGD:731433 6480464 Carbon Tetrachloride results in increased expression of TIMP1 mRNA, Carbon Tetrachloride results in increased expression of TIMP1 protein CTD PMID:14999682 more ... tetrachloromethane affects expression EXP 6480464 Carbon Tetrachloride affects the expression of TIMP1 mRNA CTD PMID:16239168 tetrachloromethane multiple interactions ISO RGD:731433 6480464 (+)-JQ1 compound inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA] more ... CTD PMID:14999682 more ... tetracycline increases expression EXP 6480464 Tetracycline results in increased expression of TIMP1 mRNA CTD PMID:17522070 tetramethylpyrazine multiple interactions EXP 6480464 tetramethylpyrazine inhibits the reaction [Hydrogen Peroxide results in increased expression of TIMP1 protein] CTD PMID:23022513 tetraphene increases expression ISO RGD:1347215 6480464 benz(a)anthracene results in increased expression of TIMP1 mRNA CTD PMID:22579512 thalidomide multiple interactions EXP 6480464 Thalidomide inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA] more ... CTD PMID:15464241 , PMID:17030452 theophylline increases expression EXP 6480464 Theophylline results in increased expression of TIMP1 mRNA CTD PMID:17522070 thioacetamide multiple interactions ISO RGD:731433 6480464 [Ethanol co-treated with Thioacetamide] results in increased expression of TIMP1 mRNA more ... CTD PMID:16126171 more ... thioacetamide increases expression ISO RGD:731433 6480464 Thioacetamide results in increased expression of TIMP1 mRNA, Thioacetamide results in increased expression of TIMP1 protein CTD PMID:16126171 more ... thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of TIMP1 mRNA, Thioacetamide results in increased expression of TIMP1 protein CTD PMID:11925456 more ... thioacetamide multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of TIMP1 mRNA more ... CTD PMID:11925456 more ... titanium atom increases secretion ISO RGD:1347215 6480464 Titanium results in increased secretion of TIMP1 protein CTD PMID:14661256 titanium dioxide increases expression ISO RGD:731433 6480464 titanium dioxide results in increased expression of TIMP1 mRNA CTD PMID:21259345 more ... titanium dioxide multiple interactions ISO RGD:731433 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TIMP1 mRNA CTD PMID:29950665 toluene 2,4-diisocyanate multiple interactions ISO RGD:1347215 6480464 Toluene 2, 4-Diisocyanate results in increased expression of and results in increased activity of TIMP1 protein CTD PMID:12534559 toluene 2,4-diisocyanate increases expression ISO RGD:731433 6480464 Toluene 2 more ... CTD PMID:14987308 tomatidine increases expression ISO RGD:1347215 6480464 tomatidine results in increased expression of TIMP1 mRNA CTD PMID:23566884 topotecan increases expression EXP 6480464 Topotecan results in increased expression of TIMP1 mRNA CTD PMID:25729387 topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of TIMP1 mRNA CTD PMID:25729387 tranexamic acid multiple interactions ISO RGD:731433 6480464 Tranexamic Acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of TIMP1 mRNA] CTD PMID:24633426 trans-anethole increases expression ISO RGD:1347215 6480464 anethole results in increased expression of TIMP1 mRNA CTD PMID:21212515 triclosan decreases expression ISO RGD:1347215 6480464 Triclosan results in decreased expression of TIMP1 mRNA CTD PMID:26604029 trimellitic anhydride increases expression ISO RGD:731433 6480464 trimellitic anhydride results in increased expression of TIMP1 mRNA CTD PMID:19042947 trimellitic anhydride affects expression ISO RGD:731433 6480464 trimellitic anhydride affects the expression of TIMP1 mRNA CTD PMID:22302311 tris(2-butoxyethyl) phosphate affects expression ISO RGD:1347215 6480464 tris(2-butoxyethyl) phosphate affects the expression of TIMP1 mRNA CTD PMID:29024780 troglitazone multiple interactions ISO RGD:1347215 6480464 troglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TIMP1 mRNA] CTD PMID:18155510 undecane increases expression EXP 6480464 undecane results in increased expression of TIMP1 protein CTD PMID:17337753 urethane increases expression ISO RGD:1347215 6480464 Urethane results in increased expression of TIMP1 mRNA CTD PMID:28818685 ursolic acid multiple interactions EXP 6480464 2 more ... CTD PMID:27274199 valproic acid decreases methylation ISO RGD:1347215 6480464 Valproic Acid results in decreased methylation of TIMP1 gene CTD PMID:29154799 valproic acid affects expression ISO RGD:1347215 6480464 Valproic Acid affects the expression of TIMP1 mRNA CTD PMID:25979313 valsartan multiple interactions ISO RGD:1347215 6480464 Valsartan inhibits the reaction [AGT protein results in increased expression of TIMP1 mRNA], Valsartan inhibits the reaction [AGT protein results in increased expression of TIMP1 protein] CTD PMID:12846741 valsartan multiple interactions EXP 6480464 [Valsartan co-treated with Fosinopril] results in decreased expression of TIMP1 mRNA more ... CTD PMID:15504291 , PMID:21051829 valsartan decreases expression EXP 6480464 Valsartan results in decreased expression of TIMP1 mRNA, Valsartan results in decreased expression of TIMP1 protein CTD PMID:21051829 vanadium atom decreases expression ISO RGD:1347215 6480464 Vanadium results in decreased expression of TIMP1 mRNA CTD PMID:19000753 vanadium(0) decreases expression ISO RGD:1347215 6480464 Vanadium results in decreased expression of TIMP1 mRNA CTD PMID:19000753 vanadium(3+) decreases expression ISO RGD:1347215 6480464 Vanadium results in decreased expression of TIMP1 mRNA CTD PMID:19000753 vancomycin increases expression EXP 6480464 Vancomycin results in increased expression of TIMP1 mRNA CTD PMID:18289764 verapamil affects expression ISO RGD:1347215 6480464 Verapamil affects the expression of TIMP1 protein CTD PMID:12388792 verapamil multiple interactions EXP 6480464 Verapamil inhibits the reaction [ferrous sulfate results in increased expression of TIMP1 protein] CTD PMID:27095094 vincaleukoblastine increases expression EXP 6480464 Vinblastine results in increased expression of TIMP1 mRNA CTD PMID:20624997 vinclozolin affects expression EXP 6480464 vinclozolin affects the expression of TIMP1 mRNA CTD PMID:19015723 vinclozolin increases expression EXP 6480464 vinclozolin results in increased expression of TIMP1 mRNA CTD PMID:22570695 vincristine increases expression EXP 6480464 Vincristine results in increased expression of TIMP1 mRNA CTD PMID:20624997 vincristine increases expression ISO RGD:1347215 6480464 Vincristine results in increased expression of TIMP1 mRNA CTD PMID:23649840 vitamin E increases expression ISO RGD:1347215 6480464 Vitamin E results in increased expression of TIMP1 mRNA CTD PMID:19244175 vitamin E multiple interactions EXP 6480464 [silybin co-treated with Phosphatidylcholines co-treated with Vitamin E] inhibits the reaction [Dimethylnitrosamine results in increased expression of TIMP1 mRNA] CTD PMID:16169303 XL147 multiple interactions ISO RGD:731433 6480464 [N-nitroso-tris-chloroethylurea co-treated with XL147] results in increased expression of TIMP1 mRNA CTD PMID:27935865 zinc protoporphyrin multiple interactions ISO RGD:1347215 6480464 zinc protoporphyrin promotes the reaction [ALB protein results in increased expression of TIMP1 protein] CTD PMID:21163135 zinc protoporphyrin affects expression EXP 6480464 zinc protoporphyrin affects the expression of TIMP1 CTD PMID:23704825 zoledronic acid increases expression ISO RGD:731433 6480464 zoledronic acid results in increased expression of TIMP1 mRNA CTD PMID:28871336 zoledronic acid multiple interactions ISO RGD:731433 6480464 Fenofibrate inhibits the reaction [zoledronic acid results in increased expression of TIMP1 mRNA], SLC27A2 gene mutant form inhibits the reaction [zoledronic acid results in increased expression of TIMP1 mRNA] CTD PMID:28871336 zoledronic acid increases expression ISO RGD:1347215 6480464 zoledronic acid results in increased expression of TIMP1 mRNA, zoledronic acid results in increased expression of TIMP1 protein CTD PMID:28871336
Gene-Chemical Interaction Annotations
