Mef2a (myocyte enhancer factor 2a)

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Gene: Mef2a (myocyte enhancer factor 2a) Rattus norvegicus

Analyze

Symbol:

Mef2a

Name:

myocyte enhancer factor 2a

RGD ID:

1359360

Description:

Enables DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Involved in several processes, including cellular response to calcium ion; cellular response to glucose stimulus; and dendrite morphogenesis. Located in nucleus. Human ortholog(s) of this gene implicated in dilated cardiomyopathy. Orthologous to human MEF2A (myocyte enhancer factor 2A); INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2-amino-2-deoxy-D-glucopyranose.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

LOC309957; myocyte-specific enhancer factor 2A; similar to myocyte enhancer factor 2C

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	MEF2A (myocyte enhancer factor 2A)	RGD	RGD
Mus musculus (house mouse):	Mef2a (myocyte enhancer factor 2A)	RGD	RGD
Chinchilla lanigera (long-tailed chinchilla):	Mef2a (myocyte enhancer factor 2A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	MEF2A (myocyte enhancer factor 2A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	MEF2A (myocyte enhancer factor 2A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Mef2a (myocyte enhancer factor 2A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	MEF2A (myocyte enhancer factor 2A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	MEF2A (myocyte enhancer factor 2A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Mef2a (myocyte enhancer factor 2A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	MEF2A (myocyte enhancer factor 2A)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Mus musculus (house mouse):	Mef2a (myocyte enhancer factor 2A)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector)
Danio rerio (zebrafish):	mef2aa (myocyte enhancer factor 2aa)	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	Mef2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PhylomeDB)
Saccharomyces cerevisiae (baker's yeast):	RLM1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|OrthoInspector\|PANTHER)
Caenorhabditis elegans (roundworm):	mef-2	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	1	120,847,874 - 120,982,488 (-)	NCBI	mRatBN7.2
mRatBN7.2 Ensembl	1	120,850,080 - 120,981,948 (-)	Ensembl
Rnor_6.0	1	128,207,715 - 128,341,681 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	128,209,971 - 128,341,263 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	129,273,893 - 129,407,071 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.1	1	122,128,377 - 122,183,406 (-)	NCBI
Celera	1	113,052,879 - 113,157,227 (-)	NCBI		Celera
Cytogenetic Map	1	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

chromosome 15q26-qter deletion syndrome (ISO)

coronary artery disease (ISO,ISS)

Coronary Artery Disease, Autosomal Dominant 1 (ISO)

dilated cardiomyopathy (ISO)

Experimental Diabetes Mellitus (IEP)

myocardial infarction (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (EXP,ISO)

17alpha-ethynylestradiol (EXP)

17beta-estradiol (ISO)

17beta-hydroxy-5alpha-androstan-3-one (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2-amino-2-deoxy-D-glucopyranose (EXP,ISO)

3,4-methylenedioxymethamphetamine (ISO)

4-phenylbutyric acid (EXP,ISO)

5-azacytidine (ISO)

acrolein (ISO)

acrylamide (ISO)

aflatoxin B1 (ISO)

aldehydo-D-glucosamine (EXP,ISO)

alpha-pinene (ISO)

benzene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

beta-D-glucosamine (EXP,ISO)

bis(2-chloroethyl) sulfide (ISO)

bisphenol A (EXP,ISO)

cadmium dichloride (EXP,ISO)

caffeine (EXP)

carbamazepine (ISO)

chloroprene (EXP)

choline (ISO)

cocaine (EXP)

coumestrol (ISO)

Cuprizon (EXP)

cyclosporin A (ISO)

dantrolene (EXP)

dibutyl phthalate (EXP)

diclofenac (ISO)

dimethylselenide (ISO)

dioxygen (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (EXP)

enniatin (EXP)

Enterolactone (ISO)

ethanol (ISO)

folic acid (ISO)

geraniol (ISO)

hydrogen cyanide (ISO)

L-methionine (ISO)

lead diacetate (ISO)

leflunomide (ISO)

metformin (ISO)

methylmercury chloride (ISO)

metoprolol (EXP)

nickel atom (ISO)

nitric oxide (ISO)

oxytocin (ISO)

ozone (ISO)

paracetamol (ISO)

phenobarbital (ISO)

phenylmercury acetate (ISO)

propiconazole (ISO)

raloxifene (ISO)

reactive oxygen species (ISO)

S-butyl-DL-homocysteine (S,R)-sulfoximine (ISO)

SB 431542 (ISO)

sodium arsenate (ISO)

sodium arsenite (EXP)

succimer (ISO)

sulfates (ISO)

tamoxifen (ISO)

tauroursodeoxycholic acid (EXP,ISO)

theophylline (ISO)

topotecan (EXP)

torcetrapib (ISO)

trichostatin A (ISO)

triptonide (ISO)

urethane (ISO)

valproic acid (ISO)

vinclozolin (EXP)

vorinostat (ISO)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

apoptotic process (IEA)

cardiac conduction (IEA,ISO)

cell differentiation (IBA)

cellular response to calcium ion (IDA,IEA,ISO)

cellular response to glucose stimulus (IEP)

dendrite morphogenesis (IMP)

ERK5 cascade (IEA,ISO,ISS)

heart development (IBA,ISO)

MAPK cascade (ISO,ISS)

mitochondrial genome maintenance (IEA,ISO)

mitochondrion distribution (IEA,ISO)

negative regulation of transcription by RNA polymerase II (IEA,ISO,ISS)

nervous system development (IEA)

positive regulation of cardiac muscle hypertrophy (IEA,ISO)

positive regulation of gene expression (IEA,ISO)

positive regulation of glucose import (IEA,ISO)

positive regulation of transcription by RNA polymerase II (IBA,IDA,IEA,IMP,ISO)

positive regulation of transcription, DNA-templated (IMP,ISO)

regulation of transcription by RNA polymerase II (IBA)

regulation of transcription, DNA-templated (ISO)

transcription, DNA-templated (IEA,ISO)

ventricular cardiac myofibril assembly (IEA,ISO)

Cellular Component

chromatin (IEA,ISO)

cytosol (IEA,ISO)

nucleoplasm (IEA,ISO,TAS)

nucleus (IDA,IEA,ISO,ISS)

transcription regulator complex (IEA,ISO)

Molecular Function

chromatin binding (IEA,ISO,ISS)

DNA binding (ISO)

DNA-binding transcription activator activity, RNA polymerase II-specific (IEA,ISO)

DNA-binding transcription factor activity (ISO)

DNA-binding transcription factor activity, RNA polymerase II-specific (IBA,IDA,ISO)

DNA-binding transcription factor binding (ISO,ISS)

histone acetyltransferase binding (IEA,ISO,ISS)

histone deacetylase binding (IBA,IEA,ISO,ISS)

protein binding (ISO)

protein dimerization activity (IEA)

protein heterodimerization activity (IEA,ISO)

protein kinase binding (IEA,ISO)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (IBA,IEA,ISO)

RNA polymerase II transcription regulatory region sequence-specific DNA binding (IEA,ISO,ISS)

RNA polymerase II-specific DNA-binding transcription factor binding (IEA,ISO)

sequence-specific DNA binding (IDA,ISO)

SMAD binding (IEA,ISO,ISS)

References

References - curated


1.	Clark AL and Naya FJ, J Biol Chem. 2015 Sep 18;290(38):23162-72. doi: 10.1074/jbc.M115.672659. Epub 2015 Aug 3.
2.	Feng B, etal., Am J Physiol Endocrinol Metab. 2008 Jun;294(6):E1119-26. Epub 2008 Apr 15.
3.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.	Kobarg CB, etal., FEBS Lett. 2005 May 9;579(12):2615-22. Epub 2005 Apr 8.
5.	Leupin O, etal., J Bone Miner Res. 2007 Dec;22(12):1957-67.
6.	Mao Z and Wiedmann M, J Biol Chem. 1999 Oct 22;274(43):31102-7.
7.	OMIM Disease Annotation Pipeline
8.	RGD automated data pipeline
9.	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10.	RGD automated import pipeline for gene-chemical interactions
11.	Shalizi A, etal., Science. 2006 Feb 17;311(5763):1012-7.
12.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
13.	Wang Q Curr Atheroscler Rep. 2005 May;7(3):235-41.
14.	Xu J, etal., J Biol Chem. 2006 Apr 7;281(14):9152-62. Epub 2006 Feb 9.

Additional References at PubMed

PMID:7760790	PMID:8096811	PMID:8900141	PMID:9013788	PMID:9430690	PMID:9738004	PMID:9858528	PMID:10458488	PMID:10748098	PMID:10835359	PMID:11160896	PMID:12097321
PMID:12130539	PMID:12379849	PMID:12826611	PMID:15132737	PMID:15466416	PMID:15491989	PMID:15735306	PMID:16024167	PMID:16043483	PMID:16407236	PMID:16484497	PMID:16985263
PMID:17431507	PMID:17630987	PMID:17785444	PMID:17855618	PMID:18198354	PMID:19197241	PMID:19362076	PMID:20363751	PMID:20399744	PMID:20590529	PMID:20833138	PMID:21379568
PMID:21468593	PMID:21724844	PMID:22194471	PMID:22622902	PMID:23261540	PMID:23349925	PMID:23424201	PMID:23486945	PMID:24161931	PMID:25089838	PMID:25147362	PMID:28263745
PMID:28473466	PMID:29588465	PMID:29606596	PMID:29678571	PMID:29783071	PMID:29928931	PMID:32485181

Genomics

Comparative Map Data

Mef2a
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	1	120,847,874 - 120,982,488 (-)	NCBI	mRatBN7.2
mRatBN7.2 Ensembl	1	120,850,080 - 120,981,948 (-)	Ensembl
Rnor_6.0	1	128,207,715 - 128,341,681 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	128,209,971 - 128,341,263 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	129,273,893 - 129,407,071 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.1	1	122,128,377 - 122,183,406 (-)	NCBI
Celera	1	113,052,879 - 113,157,227 (-)	NCBI		Celera
Cytogenetic Map	1	q22	NCBI

MEF2A
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	15	99,565,417 - 99,716,466 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	15	99,565,417 - 99,716,488 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	15	100,105,622 - 100,256,693 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	15	97,956,185 - 98,071,524 (+)	NCBI	NCBI36		hg18	NCBI36
Build 34	15	97,956,184 - 98,071,524	NCBI
Celera	15	76,525,015 - 76,675,549 (+)	NCBI
Cytogenetic Map	15	q26.3	NCBI
HuRef	15	76,235,794 - 76,386,442 (+)	NCBI		HuRef
CHM1_1	15	99,947,526 - 100,097,943 (+)	NCBI		CHM1_1

Mef2a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	66,880,911 - 67,026,435 (-)	NCBI	GRCm39		mm39
GRCm39 Ensembl	7	66,880,911 - 67,022,606 (-)	Ensembl
GRCm38	7	67,231,163 - 67,376,456 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	67,231,163 - 67,372,858 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	74,378,710 - 74,517,744 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	7	67,112,774 - 67,251,808 (-)	NCBI			mm8
Celera	7	64,692,674 - 64,806,488 (-)	NCBI		Celera
Cytogenetic Map	7	C	NCBI
cM Map	7	36.72	NCBI

Mef2a
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955416	26,953,798 - 27,051,171 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955416	26,926,753 - 27,051,171 (+)	NCBI	ChiLan1.0	ChiLan1.0

MEF2A
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	15	97,428,808 - 97,579,092 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	15	97,428,744 - 97,579,092 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	15	78,246,439 - 78,396,720 (+)	NCBI	Mhudiblu_PPA_v0		panPan3

MEF2A
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	3	41,012,103 - 41,177,588 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	3	41,015,713 - 41,179,448 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	3	43,686,343 - 43,878,500 (-)	NCBI
ROS_Cfam_1.0	3	41,389,861 - 41,582,392 (-)	NCBI
UMICH_Zoey_3.1	3	40,922,313 - 41,112,375 (-)	NCBI
UNSW_CanFamBas_1.0	3	41,153,499 - 41,343,252 (-)	NCBI
UU_Cfam_GSD_1.0	3	41,373,135 - 41,563,186 (-)	NCBI

Mef2a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	142,352,128 - 142,499,799 (+)	NCBI
SpeTri2.0	NW_004936483	3,837,891 - 3,982,334 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MEF2A
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	138,341,153 - 138,511,311 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	138,398,270 - 138,508,639 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	154,615,130 - 154,689,503 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MEF2A
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	29	18,150,315 - 18,312,975 (+)	NCBI	ChlSab1.1		chlSab2
ChlSab1.1 Ensembl	29	18,150,854 - 18,309,247 (+)	Ensembl	ChlSab1.1		chlSab2
Vero_WHO_p1.0	NW_023666059	28,253,312 - 28,416,154 (-)	NCBI	Vero_WHO_p1.0

Mef2a
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624768	4,701,734 - 4,852,833 (-)	NCBI	HetGla_female_1.0		hetGla2

Position Markers

BF390775

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	120,863,112 - 120,863,262 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	128,222,938 - 128,223,087	NCBI	Rnor6.0
Rnor_5.0	1	129,288,675 - 129,288,824	UniSTS	Rnor5.0
Celera	1	113,065,868 - 113,066,017	UniSTS
RH 3.4 Map	1	1466.59	UniSTS
Cytogenetic Map	1	q22	UniSTS

AU048441

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	120,856,288 - 120,856,447 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	128,216,130 - 128,216,288	NCBI	Rnor6.0
Rnor_5.0	1	129,282,308 - 129,282,466	UniSTS	Rnor5.0
Celera	1	113,059,044 - 113,059,202	UniSTS
Cytogenetic Map	1	q22	UniSTS

Mef2a

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	120,882,766 - 120,882,900 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	128,242,704 - 128,242,837	NCBI	Rnor6.0
Rnor_5.0	1	129,308,375 - 129,308,508	UniSTS	Rnor5.0
Celera	1	113,085,480 - 113,085,613	UniSTS
Cytogenetic Map	1	q22	UniSTS

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1358359	Sradr1	Stress Responsive Adrenal Weight QTL 1	4.74		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	30882023	123479925	Rat
70225	Bp58	Blood pressure QTL 58	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	32356093	162846471	Rat
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	32737458	199368955	Rat
2313402	Anxrr24	Anxiety related response QTL 24			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	1	48963584	144267916	Rat
1578654	Bss10	Bone structure and strength QTL 10	4		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	1	49393172	159356837	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	49393289	199050459	Rat
2298545	Neuinf8	Neuroinflammation QTL 8	4.6		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	1	57336763	151090257	Rat
1358192	Ept13	Estrogen-induced pituitary tumorigenesis QTL 13	3.4		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	1	77494165	122494165	Rat
10054135	Gmadr2	Adrenal mass QTL 2	1.97	0.0129	adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	77857876	122857876	Rat
61344	Bp29	Blood pressure QTL 29	7.5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	78350581	123350581	Rat
7411712	Strs4	Sensitivity to stroke QTL 4	8.7		cerebrum integrity trait (VT:0010549)	percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)	1	78430536	123430536	Rat
1582234	Gluco18	Glucose level QTL 18	3.4	0.0003	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	78479925	123479925	Rat
4889494	Scort2	Serum corticosterone level QTL 2	4.2		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	1	80592172	125592172	Rat
1578780	Cm52	Cardiac mass QTL 52	3.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	1	81591954	219808434	Rat
738022	Anxrr13	Anxiety related response QTL 13	4.6	0.00039	locomotor behavior trait (VT:0001392)	number of 20 x 20 cm floor squares crossed into, out of or within a discrete space in an experimental apparatus (CMO:0001514)	1	83547917	128547917	Rat
724529	Cm16	Cardiac mass QTL 16	2.7		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	1	87580395	150700247	Rat
724521	Uae1	Urinary albumin excretion QTL 1	3.8	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	90508614	173018436	Rat
1358902	Bw47	Body weight QTL 47	1.67		body mass (VT:0001259)	body weight (CMO:0000012)	1	90508614	180359386	Rat
1302788	Scl19	Serum cholesterol QTL 19	4.6	0.001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	90532338	123479925	Rat
1300153	Bp171	Blood pressure QTL 171	3.37		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	90664883	143200202	Rat
2293142	Bp314	Blood pressure QTL 314			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	92184926	137184926	Rat
724567	Tcas6	Tongue tumor susceptibility QTL 6	6.85		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	1	92948896	144267916	Rat
1331793	Bp200	Blood pressure QTL 200	3.71601		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	94494440	172949803	Rat
1331751	Bp199	Blood pressure QTL 199	3.60022		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	94494440	181830018	Rat
1331749	Hrtrt11	Heart rate QTL 11	2.973		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	1	94494440	198211706	Rat
70209	Niddm23	Non-insulin dependent diabetes mellitus QTL 23	2.82		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	94494440	198324465	Rat
731168	Bp154	Blood pressure QTL 154	3.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	94642722	214537671	Rat
61346	Rf2	Renal disease susceptibility QTL 2	3.7		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	1	99267916	144267916	Rat
61399	Tcat1	Tongue tumor resistance QTL 1	3.3		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 5 mm (CMO:0001879)	1	99267916	144267916	Rat
8655649	Arrd1	Age-related retinal degeneration QTL 1	4.89		retinal layer morphology trait (VT:0003727)	percentage of study population developing retinopathy during a period of time (CMO:0002453)	1	100357752	183970443	Rat
2317833	Alcrsp19	Alcohol response QTL 19	12.4	0.001	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	1	100979852	145979852	Rat
1641897	Alcrsp1	Alcohol response QTL 1			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	1	100979852	145979852	Rat
2303591	Gluco41	Glucose level QTL 41	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	102168504	147168504	Rat
61370	Mcs3	Mammary carcinoma susceptibility QTL 3	2.15		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	1	102268556	147268556	Rat
1354623	Rf46	Renal function QTL 46	3.8		blood creatinine amount (VT:0005328)	plasma creatinine level (CMO:0000537)	1	102813953	151162766	Rat
1354591	Cm36	Cardiac mass QTL 36	4.1		heart left ventricle mass (VT:0007031)	calculated heart weight (CMO:0000073)	1	102813953	201278233	Rat
1354615	Cm32	Cardiac mass QTL 32	5.2		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	1	102813953	201278233	Rat
1354606	Bp246	Blood pressure QTL 246	3.6		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	1	102813953	218753816	Rat
9590300	Scort16	Serum corticosterone level QTL 16	4.39	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	1	103111621	148111621	Rat
8694370	Bw154	Body weight QTL 154	8.91	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	1	103111621	148111621	Rat
631569	Bp93	Blood pressure QTL 93		0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	106047847	121834139	Rat
631496	Bp97	Blood pressure QTL 97	3.08		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	106047847	151047847	Rat
1300158	Bp173	Blood pressure QTL 173	3.48		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	1	115540693	185145286	Rat
7794788	Mcs32	Mammary carcinoma susceptibility QTL 32	2.61		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	1	115540693	238914717	Rat
631199	Cm23	Cardiac mass QTL 23	4.6	0.0004	heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	1	115585465	172949803	Rat
7421630	Bp362	Blood pressure QTL 362		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	118608292	241799120	Rat
2313060	Bss71	Bone structure and strength QTL 71	2.6	0.0001	long bone metaphysis morphology trait (VT:0000133)	tibia midshaft total cross-sectional area (CMO:0001715)	1	118944747	163944747	Rat
631205	Bp196	Blood pressure QTL 196	4	0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	118944897	199050459	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	898
Count of miRNA genes:	222
Interacting mature miRNAs:	289
Transcripts:	ENSRNOT00000070864, ENSRNOT00000072915
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	42	36	20	19	20	8	10	74	35	38	11	8
Low		1	21	21		21		1			3
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001014035	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008759541	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008759542	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017589308	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039080825	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039080830	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039080833	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039080839	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039080843	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039080850	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC081907	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473980	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DQ323505	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GU646868	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000039	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000070864 ⟹ ENSRNOP00000065122

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	120,850,098 - 120,981,948 (-)	Ensembl
Rnor_6.0 Ensembl	1	128,211,192 - 128,341,240 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000072915 ⟹ ENSRNOP00000064552

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	120,850,080 - 120,981,914 (-)	Ensembl
Rnor_6.0 Ensembl	1	128,209,971 - 128,341,263 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000084946 ⟹ ENSRNOP00000068554

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	120,850,080 - 120,981,914 (-)	Ensembl
Rnor_6.0 Ensembl	1	128,211,391 - 128,287,151 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000089723 ⟹ ENSRNOP00000068690

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	120,850,080 - 120,981,914 (-)	Ensembl
Rnor_6.0 Ensembl	1	128,211,391 - 128,287,151 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000113672 ⟹ ENSRNOP00000094055

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	120,850,098 - 120,981,948 (-)	Ensembl

RefSeq Acc Id:

NM_001014035 ⟹ NP_001014057

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	120,850,123 - 120,981,960 (-)	NCBI
Rnor_6.0	1	128,209,964 - 128,341,263 (-)	NCBI
Rnor_5.0	1	129,273,893 - 129,407,071 (-)	NCBI
Celera	1	113,052,879 - 113,157,227 (-)	RGD

Sequence:

show sequence

CCGGCGAGTCCCGGGCTGAAGGAGGCGGCTCCGGGCGGCGCGGAGTGCTGTGGCGGGCCGGGCC
GGGGCTGCGGCGTATGCGCGCCCGCCGGCTGTAGCGGAGACTCGGAATTGCATCTTGTGGAAAA
GGAACAAAGAAGAACTTTCTGCAAGGATAAAATATTTTTAAGACAATTTCAGCGGCAGCCTTGG
ACTGGAAGGTTAAATAATAGGAACTGTGTACGATGCATTAGGATATTGAAGAAAATTAGCTTCT
GAATTAATTATTTGGAATATAAGGAAGAAAAGGTGACTTTTGAAAATGGGGCGAAAGAAAATAC
AAATTACACGCATAATGGATGAGAGGAACCGACAGGTGACTTTTACAAAGCGAAAGTTCGGATT
GATGAAGAAAGCCTATGAACTCAGTGTGCTCTGTGACTGTGAGATAGCACTCATCATCTTCAAC
AGCTCTAACAAGTTGTTTCAGTACGCCAGCACTGACATGGACAAAGTCCTTCTCAAGTACACCG
AGTACAACGAGCCTCATGAAAGCAGGACGAACTCGGATATTGTGGAGGCTCTGAACAAGAAGGA
ACACAGAGGCTGCGACAGCCCAGACCCTGATACTTCATATGTGCTAACTCCACATACAGAAGAA
AAATATAAAAAAATTAATGAGGAATTTGATAATATGATGCGGAATCATAAAATCGCACCTGGCT
TGCCGCCTCAGAACTTCTCAATGTCTGTCACAGTCCCTGTGACCAGCCCTAATGCTTTGTCGTA
CACTAACCCAGGGAGTTCACTCGTGTCACCGTCTTTGGCAGCCAGCTCAACATTAGCAGAGTCC
AGCATGCTGTCTCCACCCCCAGCCACGCTACATAGAAATGTGTCTCCAGGAGCTCCGCAGAGAC
CACCAAGCACTGGCAGTGCAGGTGGGATGTTGAGCACTACAGACCTCACGGTACCAAATGGAGC
TGGAAATAGTCCTGTGGGGAATGGATTTGTAAACTCAAGGGCCTCTCCAAATTTGATTGGAAAT
ACTGGTGCGAATAGTGTAGGCAAAGTCATGCCTACAAAGTCCCCCCCGCCACCAGGTGGGGGCA
GTGTTGGAATGAACAGTCGGAAACCAGATCTACGGGTTGTCATTCCCCCTTCAAGCAAGGGCAT
GATGCCCCCACTTAATGCCCAAAGGATAAGTAGTTCTCAAGCCACACAACCTCTTGCCACGCCC
GTGGTGTCTGTGACAACTCCAAGCTTGCCTCCGCAGGGACTAGTGTACTCGGCCATGCCGACAG
CCTACAACACTGATTACTCATTGACCAGCGCTGACCTGTCCGCCCTGCAAGGCTTTACTTCCCC
TGGAATGCTGTCTCTGGGGCAGGCTTCAGCCTGGCAGCAGCACCATCTAGGACAAGCGGCCCTC
AGCTCTCTAGTGGCTGGAGGGCAGTTATCTCAGGGTTCAAATTTGTCCATTAACACCAACCAGA
ACATCAACATTAAGTCAGAGCCAATTTCACCTCCCCGTGATAGAATGACCCCATCAGGCTTCCA
GCAGCAGCAGCAGCAGCAGCCACAGCAGCAACCACCGCCACAACCTCCACAGCCCCAGCCCCAA
CCCCGGCAGGAAATGGGGCGCTCCCCTGTGGACAGTCTGAGCAGCTCTAGCAGCTCCTACGATG
GCAGTGACCGGGAGGATCCACGGGGCGACTTCCATTCTCCAATTGTGCTTGGCCGACCTCCAAA
TGCTGAGGACAGAGAAAGCCCCTCTGTAAAACGCATGAGGATGGACACATGGGTGACCTAAGGC
TTCCTGGTTCATGTCTGTTCTTTGTGTTACTGCAGTGAACTGCCCTACATATCTTAAATTGGTG
AATAAGGACATGAGTTCAATATATTTATATGTACATGCATACATATATATCCCTTTACATATAT
ATGTATGTCGGTGTGAGTGTGTGTATGTGTGGGTGTGTGTTGCATACACAGAATCAGGCACTTA
CTGCGACTCCTTGTAGGTATGCAGATGTGTGCACACGGCACACAGAGCACCTTGTAGAGACAGA
CCAGCCTGGCACTTCCTTGGACTACTTGTCTCCTAAGATAAAGTTTTTGCAGAGAAACGTGTAC
CCATATATAATTCTTCCACATTAGCCTGCAGAAACCTAGGGGCCCCTATTTGTTTTATTTACCT
GTGCGGTGACTGTAGTTACTTCAAAAAAAAAAAAAATTGCTTTGTAGAACAGAGCAGTAGAAAA
GCAGGAACCAAGAAAGCAATACTGTACATAAAGTCATTTATATTAATAACCCAACCTGGCATGG
GTCTATTGCAGAGGGGTGCATGGGCAAGGGCTGTCTATATTAAACAGACACAGTAAACAAAGAG
CCCCACACATAACTGTTTTGCACGTGCAAAAAAATGTATTGGGTCAAAGAAGTGATTTTTAGCT
ATTAAAAAGAGAGAATAGAAAACACGCATGAAATATTCAGAAATACTAGCCTAGAAATATAGAG
CATTAACAAAATAAAATTAATATATTAGTTATAATTGGAATATGTCAGAAGTTTCTTTTACATT
CATATCTTTAAAAATTAAAGAAACTGATTTTAGGTCATGTATATTTTATATGAAAGAAAACACC
CTTAATGAATTGATGACTATATATAAAATTATATCCACTACTTTTGAACACATTCTGCTGAATT
ATTTATATAAGCCAAAGCTGTATGTTGTAACTTTTTTTTTTAAAGAATAGCTTTATCTTGTTTT
AACTTTTTAGTTTTATTTTAAGAGGGAAGAAAAAAACAAAAATATCTTGCAAGCAGAACCTTGG
AAAAAAAAAAAGCCATGAACATTATTATTCTATATGTAAATTAAAAGTCGAGCCAAACTCTTTG
TGTATATAGCATCTTAAATATATTACCACCTTTGATGTAAGTACCTATGTATTGTATGGTCACC
AGATTAAAAAGTATATTTTTGTGGATTGCCACCAATTTGGGGGGAAAGGCGAAGTCCTTAAGTA
GAGTATTCACTGTTTAATATTTACTATTTTGTTAAATATACTGTACTTTGGATTTTAATTATTA
GCCCAGTTTTTCAGAGGATTGTGTAAAGGGGTTTCCCCTCACTGGTGGTGAATGTGTGATGTTC
TGTTGTAATCTTTGTGCTGTATGGGGTGAGCATCATTATATATTTTATATGTGTACATAAATAG
CAAAGTGGCAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_008759541 ⟹ XP_008757763

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	120,847,874 - 120,982,472 (-)	NCBI
Rnor_6.0	1	128,207,715 - 128,341,681 (-)	NCBI

Sequence:

show sequence

GAGAACACGGTCCTTCAGAGGGAAGCGCGCTCCAGGCTGCAGCCCCGGCGCCAAGCCGCCGTCA
TCTCCTTCCTGTGCCGGGTGATCTGTCGCCTCACCCACCCGGAAAAACATAGTCCGCCCCTCAT
GTCCTTGTGGAATAGCGCTAGCTGTTCAGAAGGCGCGGCTCTCTCTGACTGTTCCCTTGTCTTG
CCCATGACAAACCCTTCAGGACCCACCGAGAGCAGAAATATACCCTAAAAGGAGAGCTCGAGAG
AGAAGAAAGAGAGGAAGCCGAGAGGAAGGGAGAGGCGAGGCCGGCGGAGGGACACCAAGACGTC
CTCGCAGTGCGCACGCGCACCGCGAAGAACGAGTTCCGGTCTGGCCGAGGCCTGACTCCTAAAA
ATAGCCCCGGTGTGGGGATCCGTGCGCGGATGTCCCGGCGAGTCCCGGGCTGAAGGAGGCGGCT
CCGGGCGGCGCGGAGTGCTGTGGCGGGCCGGGCCGGGGCTGCGGCGTATGCGCGCCCGCCGGCT
GTAGCGGAGACTCGGAATTGCATCTTGTGGAAAAGGAACAAAGAAGAACTTTCTGCAAGGATAA
AATATTTTTAAGACAATTTCAGCGGCAGCCTTGGACTGGAAGGTTAAATAATAGGAACTGTGTA
CGATGCATTAGGATATTGAAGAAAATTAGCTTCTGAATTAATTATTTGGAATATAAGGAAGAAA
AGGTGACTTTTGAAAATGGGGCGAAAGAAAATACAAATTACACGCATAATGGATGAGAGGAACC
GACAGGTGACTTTTACAAAGCGAAAGTTCGGATTGATGAAGAAAGCCTATGAACTCAGTGTGCT
CTGTGACTGTGAGATAGCACTCATCATCTTCAACAGCTCTAACAAGTTGTTTCAGTACGCCAGC
ACTGACATGGACAAAGTCCTTCTCAAGTACACCGAGTACAACGAGCCTCATGAAAGCAGGACGA
ACTCGGATATTGTGGAGACTTTAAGAAAGAAAGGCCTTAATGGTTGTGAGAGCCCTGATGCTGA
CGATTACTTTGAGCACAGTCCACTCTCGGAGGACAGATTCAGCAAACTAAATGAAGATAGTGAT
TTTATTTTCAAACGAGGCCCTCCTGGCTTGCCGCCTCAGAACTTCTCAATGTCTGTCACAGTCC
CTGTGACCAGCCCTAATGCTTTGTCGTACACTAACCCAGGGAGTTCACTCGTGTCACCGTCTTT
GGCAGCCAGCTCAACATTAGCAGAGTCCAGCATGCTGTCTCCACCCCCAGCCACGCTACATAGA
AATGTGTCTCCAGGAGCTCCGCAGAGACCACCAAGCACTGGCAGTGCAGGTGGGATGTTGAGCA
CTACAGACCTCACGGTACCAAATGGAGCTGGAAATAGTCCTGTGGGGAATGGATTTGTAAACTC
AAGGGCCTCTCCAAATTTGATTGGAAATACTGGTGCGAATAGTGTAGGCAAAGTCATGCCTACA
AAGTCCCCCCCGCCACCAGGTGGGGGCAGTGTTGGAATGAACAGTCGGAAACCAGATCTACGGG
TTGTCATTCCCCCTTCAAGCAAGGGCATGATGCCCCCACTTAATGCCCAAAGGATAAGTAGTTC
TCAAGCCACACAACCTCTTGCCACGCCCGTGGTGTCTGTGACAACTCCAAGCTTGCCTCCGCAG
GGACTAGTGTACTCGGCCATGCCGACAGCCTACAACACTGATTACTCATTGACCAGCGCTGACC
TGTCCGCCCTGCAAGGCTTTACTTCCCCTGGAATGCTGTCTCTGGGGCAGGCTTCAGCCTGGCA
GCAGCACCATCTAGGACAAGCGGCCCTCAGCTCTCTAGTGGCTGGAGGGCAGTTATCTCAGGGT
TCAAATTTGTCCATTAACACCAACCAGAACATCAACATTAAGTCAGAGCCAATTTCACCTCCCC
GTGATAGAATGACCCCATCAGGCTTCCAGCAGCAGCAGCAGCAGCAGCCACAGCAGCAACCACC
GCCACAACCTCCACAGCCCCAGCCCCAACCCCGGCAGGAAATGGGGCGCTCCCCTGTGGACAGT
CTGAGCAGCTCTAGCAGCTCCTACGATGGCAGTGACCGGGAGGATCCACGGGGCGACTTCCATT
CTCCAATTGTGCTTGGCCGACCTCCAAATGCTGAGGACAGAGAAAGCCCCTCTGTAAAACGCAT
GAGGATGGACACATGGGTGACCTAAGGCTTCCTGGTTCATGTCTGTTCTTTGTGTTACTGCAGT
GAACTGCCCTACATATCTTAAATTGGTGAATAAGGACATGAGTTCAATATATTTATATGTACAT
GCATACATATATATCCCTTTACATATATATGTATGTCGGTGTGAGTGTGTGTATGTGTGGGTGT
GTGTTGCATACACAGAATCAGGCACTTACTGCGACTCCTTGTAGGTATGCAGATGTGTGCACAC
GGCACACAGAGCACCTTGTAGAGACAGACCAGCCTGGCACTTCCTTGGACTACTTGTCTCCTAA
GATAAAGTTTTTGCAGAGAAACGTGTACCCATATATAATTCTTCCACATTAGCCTGCAGAAACC
TAGGGGCCCCTATTTGTTTTATTTACCTGTGCGGTGACTGTAGTTACTTCAAAAAAAAAAAAAA
TTGCTTTGTAGAACAGAGCAGTAGAAAAGCAGGAACCAAGAAAGCAATACTGTACATAAAGTCA
TTTATATTAATAACCCAACCTGGCATGGGTCTATTGCAGAGGGGTGCATGGGCAAGGGCTGTCT
ATATTAAACAGACACAGTAAACAAAGAGCCCCACACATAACTGTTTTGCACGTGCAAAAAAATG
TATTGGGTCAAAGAAGTGATTTTTAGCTATTAAAAAGAGAGAATAGAAAACACGCATGAAATAT
TCAGAAATACTAGCCTAGAAATATAGAGCATTAACAAAATAAAATTAATATATTAAGTTATAAT
TGGAATATGTCAGAAGTTTCTTTTACATTCATATCTTTAAAAATTAAAGAAACTGATTTTAGGT
CATGTATATTTTATATGAAAGAAAACACCCTTAATGAATTGATGACTATATATAAAATTATATC
CACTACTTTTGAACACATTCTGCTGAATTATTTATATAAGCCAAAGCTGTATGTTGTAACTTTT
TTTTTTAAAGAATAGCTTTATCTTGTTTTAACTTTTTAGTTTTATTTTAAGAGGGAAGAAAAAA
ACAAAAATATCTTGCAAGCAGAACCTTGGAAAAAAAAAAGCCATGAACATTATTATTCTATATG
TAAATTAAAAGTCGAGCCAAACTCTTTGTGTATATAGCATCTTAAATATATTACCACCTTTGAT
GTAAGTACCTATGTATTGTATGGTCACCAGATTAAAAAGTATATTTTTGTGGATTGCCACCAAT
TTGGGGGGAAAGGCGAAGTCCTTAAGTAGAGTATTCACTGTTTAATATTTACTATTTTGTTAAA
TATACTGTACTTTGGATTTTAATTATTAGCCCAGTTTTTCAGAGGATTGTGTAAAGGGGTTTCC
CCTCACTGGTGGTGAATGTGTGATGTTCTGTTGTAATCTTTGTGCTGTATGGGGTGAGCATCAT
TATATATTTTATATGTGTACATAAATAGCAAAGTGGCAAAAAAATTGGTGTTAAGTTCATCCTG
CATAAATATAAAATGTGTTGTAACAGATTTTATAAGGCATTATTTAAAACTTGCCTTTTGTGAG
GGAAAAAAAAAAACAGTAGAAAGATGACCTAATTTAACTAATATTAGAGAAAATGGCTGAGTAG
TAGATGAGCACAAAGGTTTTATAAGTGGTAAATAATTAGGAAAATATTTGTAGGGGAAGGGATC
TTTTCTCCTTGACTCTAAAGATAGAATGATGCAGCTGGTTACAAAATCCAGGAGGGCTTTAGCG
TCCCGTGCGTGGGAAGGCACGGGCGTGCAGGGAGCAGCTCTCCTATGGTGCAGATCCCCGACAC
AATTCTTGCTGTCCTGACGGAAACTGGTGCCACCCTCAGCTTGGATTTTGAACAAGGCCTTACT
CTTACAGGGAGACAGCTCGTTGGTGATGGCAAGTTCATCCGTTTACTGGGCTTGTGCCATGAAC
AAAATTCAAAGTCCTGTATATCTTTTATCCTAGATTTTTAAATACTCCTTTTCCTGAAAAAACT
TAAAGAGTTTAAAAATGGCTGCTATTTTATACTGAACAATGTTGAGCAGCTACCTGCAGTTTTT
ACTTACATTTTGCTTTTCCCCTCGATTCCCTAAATTATGCTCCTTTTGATGTCTCCTCATCTGC
TGTCCCGACAGCTCATCAGCCAGGTTTCCTGCCTGGCCGCACACAGGTATTCGGTCCATGCACC
GTGGTGAGCACAGGCTGTGCACTGGAGAGCCTCACTGACAGTCTGGGTAGCACATGTTAGTGGA
AGCCAAGGAAGTGGGGACGGTGTCTCATCTCCTCTGTGGTCTCAGCACTTGGCTCTTCCTCAGA
GAAGGTTAGGTTTTCTTCCTCAAGTGTACTGAGTTGACTTACAGGCACGTTCCTCATAAGGTCA
CAGTCTCCCAACACTGACTTTCCAAGATACCCCTTACCACTTTGTAAACCATTTATAGCTTTGA
AAGTATTAAGTGACCCTTTCATTATTATTTATGCATGTTCATGAACTTCTGCTGTATATTGGGA
TAGGAGTTAACACATTCACATTTACTGTCTATTTTCTTGTGTGCCTTATGAGATGGCTTCTCTG
ACTGTATCTCAATAGTCTTTCTATGCAGGTTTATAATCAGTACAACTACTGTTTTCTAAAGGAA
TATTACACACGGCTCGGAGTTTGTACTTAAATTACACTGACCAAGTCACAATGTATTCCGTTTT
CAGGAACTGAATATCTGACTGTTAATCTTTTCCCATATGCCCAGTGTGATCTGGAGCATATGGG
TCTGACATCCTTCACCCAGATGCTCATGTGTGAACACATCCACATCCACAGCTCTCAGTGGAAG
CCAGCCTAGAGTAGGGAGGACACTGACGGTGTTGCTTTAAACTGACTTTTCTTACCCTTTGAGA
CTCATGTGTTTTGTATAAGACACCATCACAAGAAAGTTTTCTCCCTTCAGATAACATATTTTAT
TATTAAAAAGAAAAACAAAAAAAGCTTTTAAGTTGCACTGGACGTGGGCCGTTCCTTCGGAACT
CTTTGGATCTACACTGAGAGTGAGTGTCGCCGCTCTGTGAACACAGGTGGTCCCAGTCAAAACT
CCATCCTTTGAGCCCTAATTACATCCATTGTGTTACAAAACTAAATCAGGGGTTTGTTCTAAAA
GAACAATACATGTCTCACCATTTCCTTTCAACTGTAAAGACGACTGATAATGTATTAACATAAT
TTCTGTATTAACCATCATGCGCACAAGAAATACATAGTAAATACGGAACCTGAAAACTCCTGCA
TCGGATCATAAAAGCTAGATGATTAGAATGTGAAAAGAACTTTACAGATGTAAAACTTTTATTT
CTCTGTAGAAACTTTCTTCACTTTGCTGTGCAAGAAGACACTGCTTTGCTATATTTAAAATGGC
TTTTTTAAAAAGAGATTTATGTATTTGGTAAATGTTTGTAGTCAACAGTTCACACAAAGAAGCT
GTACACGGTTTGATCATGTAAAACCGTTTGGCGGCACAAGCTGGACTTTGTTGCCATCCTTGAG
ATGAACCTTTTAAGAAAAATAAGTTAATCTCAATTTTTCCCTGAATGTGTTGTTTTTTCTTCAT
TATACAATAAATATTATAGTGAAGTTTTTATCAAATGGTTAAGACAATGCTAGAGGTTGTTGTA
AGCTATTTGTCTCCTGCACTCACTCCAGTAAAGATGGCCTGGCTTTGACCATA

hide sequence

RefSeq Acc Id:

XM_039080825 ⟹ XP_038936753

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	120,847,874 - 120,982,484 (-)	NCBI

RefSeq Acc Id:

XM_039080830 ⟹ XP_038936758

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	120,851,550 - 120,981,723 (-)	NCBI

RefSeq Acc Id:

XM_039080833 ⟹ XP_038936761

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	120,851,550 - 120,982,488 (-)	NCBI

RefSeq Acc Id:

XM_039080839 ⟹ XP_038936767

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	120,847,874 - 120,982,481 (-)	NCBI

RefSeq Acc Id:

XM_039080843 ⟹ XP_038936771

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	120,847,874 - 120,981,715 (-)	NCBI

RefSeq Acc Id:

XM_039080850 ⟹ XP_038936778

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	120,847,874 - 120,982,484 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001014057	(Get FASTA)	NCBI Sequence Viewer
	XP_008757763	(Get FASTA)	NCBI Sequence Viewer
	XP_038936753	(Get FASTA)	NCBI Sequence Viewer
	XP_038936758	(Get FASTA)	NCBI Sequence Viewer
	XP_038936761	(Get FASTA)	NCBI Sequence Viewer
	XP_038936767	(Get FASTA)	NCBI Sequence Viewer
	XP_038936771	(Get FASTA)	NCBI Sequence Viewer
	XP_038936778	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH81907	(Get FASTA)	NCBI Sequence Viewer
	ABC55063	(Get FASTA)	NCBI Sequence Viewer
	ADI49848	(Get FASTA)	NCBI Sequence Viewer
	EDM08446	(Get FASTA)	NCBI Sequence Viewer
	EDM08447	(Get FASTA)	NCBI Sequence Viewer
	EDM08448	(Get FASTA)	NCBI Sequence Viewer
	EDM08449	(Get FASTA)	NCBI Sequence Viewer
	Q2MJT0	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_001014057 ⟸ NM_001014035

- UniProtKB:

Q2MJT0 (UniProtKB/Swiss-Prot), A0A0G2JSZ4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYASTDMDK
VLLKYTEYNEPHESRTNSDIVEALNKKEHRGCDSPDPDTSYVLTPHTEEKYKKINEEFDNMMRN
HKIAPGLPPQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTLAESSMLSPPPATLHRNVS
PGAPQRPPSTGSAGGMLSTTDLTVPNGAGNSPVGNGFVNSRASPNLIGNTGANSVGKVMPTKSP
PPPGGGSVGMNSRKPDLRVVIPPSSKGMMPPLNAQRISSSQATQPLATPVVSVTTPSLPPQGLV
YSAMPTAYNTDYSLTSADLSALQGFTSPGMLSLGQASAWQQHHLGQAALSSLVAGGQLSQGSNL
SINTNQNINIKSEPISPPRDRMTPSGFQQQQQQQPQQQPPPQPPQPQPQPRQEMGRSPVDSLSS
SSSSYDGSDREDPRGDFHSPIVLGRPPNAEDRESPSVKRMRMDTWVT

hide sequence

RefSeq Acc Id:	XP_008757763 ⟸ XM_008759541
- Peptide Label:	isoform X3
- UniProtKB:	M0R6R7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYASTDMDK VLLKYTEYNEPHESRTNSDIVETLRKKGLNGCESPDADDYFEHSPLSEDRFSKLNEDSDFIFKR GPPGLPPQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTLAESSMLSPPPATLHRNVSPG APQRPPSTGSAGGMLSTTDLTVPNGAGNSPVGNGFVNSRASPNLIGNTGANSVGKVMPTKSPPP PGGGSVGMNSRKPDLRVVIPPSSKGMMPPLNAQRISSSQATQPLATPVVSVTTPSLPPQGLVYS AMPTAYNTDYSLTSADLSALQGFTSPGMLSLGQASAWQQHHLGQAALSSLVAGGQLSQGSNLSI NTNQNINIKSEPISPPRDRMTPSGFQQQQQQQPQQQPPPQPPQPQPQPRQEMGRSPVDSLSSSS SSYDGSDREDPRGDFHSPIVLGRPPNAEDRESPSVKRMRMDTWVT hide sequence

RefSeq Acc Id:

ENSRNOP00000065122 ⟸ ENSRNOT00000070864

RefSeq Acc Id:

ENSRNOP00000064552 ⟸ ENSRNOT00000072915

RefSeq Acc Id:

ENSRNOP00000068554 ⟸ ENSRNOT00000084946

RefSeq Acc Id:

ENSRNOP00000068690 ⟸ ENSRNOT00000089723

RefSeq Acc Id:	XP_038936778 ⟸ XM_039080850
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_038936753 ⟸ XM_039080825
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038936767 ⟸ XM_039080839
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038936771 ⟸ XM_039080843
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038936761 ⟸ XM_039080833
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038936758 ⟸ XM_039080830
- Peptide Label:	isoform X1

RefSeq Acc Id:

ENSRNOP00000094055 ⟸ ENSRNOT00000113672

Protein Domains

MADS-box

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13690107

Promoter ID:

EPDNEW_R631

Type:

multiple initiation site

Name:

Mef2a_1

Description:

myocyte enhancer factor 2a

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	128,341,272 - 128,341,332	EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)

ACI/EurMcwi (2019)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

ACI/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

ACI/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

ACI/N (2020)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

ACI/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

BBDP/Wor (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

BN-Lx/CubMcwi (2019)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BN/NHsdMcwi (2019)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BN/NHsdMcwi (2020)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BN/SsN (2020)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BN/SsN (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

BUF/N (2020)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BXH2/CubMcwi (2020)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BXH3/CubMcwi (2020)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

Buf/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

COP/CrCrl (MCW & UW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob) University of Wisconsin (Dr. James Shull)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Charles River Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)

DA/OlaHsd (2019)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Envigo
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

F344/DuCrl (2019)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

F344/N (2020)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

F344/NCrl (2019)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

F344/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

F344/NRrrc (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

F344/Stm (2019)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

FHH/EurMcwi (2019)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

FHH/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHH/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

FHL/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHL/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

FXLE16/Stm (2020)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

FXLE18/Stm (2020)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

GH/OmrMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

GK/FarMcwi (2019)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

GK/Ox (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

HXB10/IpcvMcwi (2019)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB2/IpcvMcwi (2019)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB20/IpcvMcwi (2020)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB31/IpcvMcwi (2019)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB4/IpcvMcwi (2020)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LE/Stm (2019)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LE/Stm (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/Crl (2019)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEW/Crl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/NCrlBR (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEXF10A/StmMcwi (2020)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF11/Stm (2020)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF1A/Stm (2019)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF1C/Stm (2019)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF2B/Stm (2019)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF3/Stm (2020)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF4/Stm (2020)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LH/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LH/MavRrrcAek (2020)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Kwitek
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LL/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LL/MavRrrcAek (2020)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Kwitek
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LN/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LN/MavRrrcAek (2020)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Kwitek
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

M520/N (2020)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

M520/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

M520/NRrrcMcwi (2019)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

MHS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MNS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MR/N (2020)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

MR/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

MWF/Hsd (2019)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

PVG/Seac (2019)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

SBH/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBH/Ygl sequenced by MCW

SBH/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SBN/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBN/Ygl sequenced by MCW

SBN/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHR/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHR/OlalpcvMcwi (2019)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

SHRSP/A3NCrl (2019)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

SHRSP/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SR/JrHsd (2020)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Envigo
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

SR/JrHsd (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Harlan Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SR/JrHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/Jr (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/JrHsdMcwi (2019)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

SS/JrHsdMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SS/JrHsdMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WAG/Rij (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WAG/RijCrl (2020)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

WKY/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/N (2020)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

WKY/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

WKY/NCrl (2019)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

WKY/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WN/N (2020)

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Sequenced By:	MCW
Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

WN/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1359360	AgrOrtholog
Ensembl Genes	ENSRNOG00000047756	Ensembl, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000064552	UniProtKB/TrEMBL
	ENSRNOP00000065122	UniProtKB/TrEMBL
	ENSRNOP00000068554	UniProtKB/TrEMBL
	ENSRNOP00000068690	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000070864	UniProtKB/TrEMBL
	ENSRNOT00000072915	UniProtKB/TrEMBL
	ENSRNOT00000084946	UniProtKB/TrEMBL
	ENSRNOT00000089723	UniProtKB/TrEMBL
Gene3D-CATH	3.40.1810.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7111112	IMAGE-MGC_LOAD
InterPro	HJURP_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	MADS_MEF2-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TF_MADSbox	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TF_MADSbox_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:309957	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE	MGC:93837	IMAGE-MGC_LOAD
NCBI Gene	309957	ENTREZGENE
Pfam	HJURP_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SRF-TF	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Mef2a	PhenoGen
PRINTS	MADSDOMAIN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	MADS_BOX_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	MADS_BOX_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	MADS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF55455	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A0G2JSZ4	ENTREZGENE, UniProtKB/TrEMBL
	A0A0G2JT35_RAT	UniProtKB/TrEMBL
	A0A0G2JTF4_RAT	UniProtKB/TrEMBL
	D8X2M2_RAT	UniProtKB/TrEMBL
	M0R6R7	ENTREZGENE, UniProtKB/TrEMBL
	MEF2A_RAT	UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary	Q66HD7	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-09-12	Mef2a	myocyte enhancer factor 2a	LOC309957	similar to myocyte enhancer factor 2C	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-07-29	LOC309957	similar to myocyte enhancer factor 2C			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - OMIM

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