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Gene: Mef2a (myocyte enhancer factor 2a) Rattus norvegicus
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Symbol: Mef2a
Name: myocyte enhancer factor 2a
Description: Exhibits DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Involved in several processes, including cellular response to calcium ion; cellular response to glucose stimulus; and dendrite morphogenesis. Localizes to the nucleus. Human ortholog(s) of this gene implicated in dilated cardiomyopathy. Orthologous to human MEF2A (myocyte enhancer factor 2A); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,2-dimethylhydrazine; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC309957; myocyte-specific enhancer factor 2A; similar to myocyte enhancer factor 2C
Orthologs:
Homo sapiens (human) : MEF2A (myocyte enhancer factor 2A)  HGNC  Alliance
Mus musculus (house mouse) : Mef2a (myocyte enhancer factor 2A)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mef2a (myocyte enhancer factor 2A)
Pan paniscus (bonobo/pygmy chimpanzee) : MEF2A (myocyte enhancer factor 2A)
Canis lupus familiaris (dog) : MEF2A (myocyte enhancer factor 2A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mef2a (myocyte enhancer factor 2A)
Sus scrofa (pig) : MEF2A (myocyte enhancer factor 2A)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01128,207,715 - 128,341,681 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01129,273,893 - 129,407,071 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.11122,128,377 - 122,183,406 (-)NCBI
Celera1113,052,879 - 113,157,227 (-)NCBICelera
Cytogenetic Map1q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Mef2a
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1359360
Created: 2005-07-29
Species: Rattus norvegicus
Last Modified: 2019-05-21
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.