Gene: Usp1 (ubiquitin specific peptidase 1) Rattus norvegicus
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Symbol: Usp1
Name: ubiquitin specific peptidase 1
Description: ENCODES a protein that exhibits peptidase activity (ortholog); thiol-dependent ubiquitin-specific protease activity (ortholog); thiol-dependent ubiquitinyl hydrolase activity (ortholog); INVOLVED IN monoubiquitinated protein deubiquitination (ortholog); protein deubiquitination (ortholog); regulation of DNA repair (ortholog); ASSOCIATED WITH Fanconi anemia (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol
AGR Description: Predicted to have cysteine-type endopeptidase activity and thiol-dependent ubiquitin-specific protease activity; predicted to be involved in several processes, including monoubiquitinated protein deubiquitination, regulation of DNA repair, and response to UV; predicted to localize to the nucleoplasm; orthologous to human USP1 (ubiquitin specific peptidase 1).
Merged Description: Predicted to have cysteine-type endopeptidase activity and thiol-dependent ubiquitin-specific protease activity; predicted to be involved in several processes, including monoubiquitinated protein deubiquitination, regulation of DNA repair, and response to UV; predicted to localize to the nucleoplasm; orthologous to human USP1 (ubiquitin specific peptidase 1); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: deubiquitinating enzyme 1; LOC313387; MGC108773; ubiquitin carboxyl-terminal hydrolase 1; ubiquitin specific peptdiase 1; ubiquitin specific protease 1; ubiquitin thioesterase 1; ubiquitin thiolesterase 1; ubiquitin-specific-processing protease 1
Orthologs:
Homo sapiens (human) : USP1 (ubiquitin specific peptidase 1)  HGNC  Alliance
Mus musculus (house mouse) : Usp1 (ubiquitin specific peptidase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Usp1 (ubiquitin specific peptidase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : USP1 (ubiquitin specific peptidase 1)
Canis lupus familiaris (dog) : USP1 (ubiquitin specific peptidase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Usp1 (ubiquitin specific peptidase 1)
Sus scrofa (pig) : USP1 (ubiquitin specific peptidase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05117,583,502 - 117,594,872 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05121,525,009 - 121,536,379 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45119,364,515 - 119,375,885 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15119,369,740 - 119,381,109 (+)NCBI
Celera5112,151,349 - 112,162,719 (+)NCBICelera
Cytogenetic Map5q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Usp1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1306461
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.