USP1 (ubiquitin specific peptidase 1) - Rat Genome Database

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Gene: USP1 (ubiquitin specific peptidase 1) Pan paniscus
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Symbol: USP1
Name: ubiquitin specific peptidase 1
RGD ID: 11830051
Description: ENCODES a protein that exhibits peptidase activity (ortholog); INVOLVED IN skeletal system development (ortholog); ASSOCIATED WITH congenital disorder of glycosylation It (ortholog); Fanconi anemia (ortholog); intellectual disability (ortholog); FOUND IN cytosol (inferred); nucleoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ubiquitin carboxyl-terminal hydrolase 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21164,400,198 - 164,427,944 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11163,549,851 - 163,577,601 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0161,694,775 - 61,710,216 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1163,509,781 - 63,525,446 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl163,510,196 - 63,525,446 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
USP1Bonobocongenital disorder of glycosylation It  ISOUSP1 (Homo sapiens)8554872ClinVar Annotator: match by term: PGM1-congenital disorder of glycosylationClinVarPMID:28492532
USP1Bonobointellectual disability  ISOUSP1 (Homo sapiens)8554872ClinVar Annotator: match by term: Intellectual disability and severeClinVarPMID:25741868
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
USP1BonoboFanconi anemia  ISOUsp1 (Mus musculus)9068941 MouseDO 


Biological Process
1 to 11 of 11 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
USP1Bonobomonoubiquitinated protein deubiquitination involved_inIEAUniProtKB:O94782 and ensembl:ENSP00000343526150520179 EnsemblGO_REF:0000107
USP1Bonobopositive regulation of receptor signaling pathway via JAK-STAT involved_inIEAUniProtKB:O94782 and ensembl:ENSP00000343526150520179 EnsemblGO_REF:0000107
USP1Bonoboprotein deubiquitination involved_inIEAInterPro:IPR001394 and InterPro:IPR033815150520179 InterProGO_REF:0000002
USP1Bonoboprotein deubiquitination involved_inIEAUniProtKB:O94782 and ensembl:ENSP00000343526150520179 EnsemblGO_REF:0000107
USP1Bonoboprotein deubiquitination involved_inIEAPANTHER:PTN002364247150520179 TreeGrafterGO_REF:0000118
USP1Bonoboproteolysis involved_inIEAUniProtKB-KW:KW-0645150520179 UniProtGO_REF:0000043
USP1Bonoboregulation of DNA repair involved_inIEAUniProtKB:O94782 and ensembl:ENSP00000343526150520179 EnsemblGO_REF:0000107
USP1Bonoboregulation of DNA repair involved_inIEAInterPro:IPR033815150520179 InterProGO_REF:0000002
USP1Bonoboresponse to UV involved_inIEAUniProtKB:O94782 and ensembl:ENSP00000343526150520179 EnsemblGO_REF:0000107
USP1Bonoboskeletal system development involved_inIEAUniProtKB:Q8BJQ2 and ensembl:ENSMUSP00000030289150520179 EnsemblGO_REF:0000107
USP1Bonoboskeletal system development acts_upstream_of_or_withinISOMGI:43635839068941 PMID:21925315MGIPMID:21925315
1 to 11 of 11 rows

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
USP1Bonobocytosol located_inIEAPANTHER:PTN002364247150520179 TreeGrafterGO_REF:0000118
USP1Bonobonucleoplasm located_inIEAUniProtKB:O94782 and ensembl:ENSP00000343526150520179 EnsemblGO_REF:0000107
USP1Bonobonucleus located_inIEAUniProtKB:O94782 and ensembl:ENSP00000343526150520179 EnsemblGO_REF:0000107
USP1Bonobonucleus located_inIEAPANTHER:PTN002364247150520179 TreeGrafterGO_REF:0000118

Molecular Function
1 to 10 of 10 rows

  
1 to 10 of 10 rows

PMID:22301074   PMID:30032202  



USP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21164,400,198 - 164,427,944 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11163,549,851 - 163,577,601 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0161,694,775 - 61,710,216 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1163,509,781 - 63,525,446 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl163,510,196 - 63,525,446 (+)Ensemblpanpan1.1panPan2
USP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38162,436,395 - 62,451,804 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl162,436,297 - 62,451,804 (+)EnsemblGRCh38hg38GRCh38
GRCh37162,902,066 - 62,917,475 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36162,674,563 - 62,690,063 (+)NCBINCBI36Build 36hg18NCBI36
Build 34162,614,699 - 62,629,430NCBI
Celera161,191,184 - 61,206,684 (+)NCBICelera
Cytogenetic Map1p31.3NCBI
HuRef161,014,014 - 61,029,515 (+)NCBIHuRef
CHM1_1163,017,306 - 63,032,808 (+)NCBICHM1_1
T2T-CHM13v2.0162,314,982 - 62,330,391 (+)NCBIT2T-CHM13v2.0
Usp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39498,812,047 - 98,823,780 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl498,812,047 - 98,823,780 (+)EnsemblGRCm39 Ensembl
GRCm38498,923,810 - 98,935,543 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl498,923,810 - 98,935,543 (+)EnsemblGRCm38mm10GRCm38
MGSCv37498,590,501 - 98,602,224 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36498,415,828 - 98,427,551 (+)NCBIMGSCv36mm8
Celera497,290,878 - 97,302,597 (+)NCBICelera
Cytogenetic Map4C6NCBI
cM Map445.6NCBI
Usp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85118,703,056 - 118,714,426 (+)NCBIGRCr8
mRatBN7.25113,587,564 - 113,598,934 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5113,587,564 - 113,598,932 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5116,161,227 - 116,172,610 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05117,886,562 - 117,897,946 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05117,949,094 - 117,960,477 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05117,583,502 - 117,594,872 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5117,583,502 - 117,594,870 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05121,525,009 - 121,536,379 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45119,364,515 - 119,375,885 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15119,369,740 - 119,381,109 (+)NCBI
Celera5112,151,349 - 112,162,719 (+)NCBICelera
Cytogenetic Map5q33NCBI
Usp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542327,237,003 - 27,251,892 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542327,236,242 - 27,254,064 (-)NCBIChiLan1.0ChiLan1.0
USP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1547,655,533 - 47,666,767 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl547,656,039 - 47,666,210 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha547,709,417 - 47,728,116 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0547,832,714 - 47,851,368 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl547,839,987 - 47,850,507 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1547,787,677 - 47,806,321 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0547,734,051 - 47,752,692 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0547,996,113 - 48,014,814 (-)NCBIUU_Cfam_GSD_1.0
Usp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505875,834,633 - 75,844,494 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936692148,116 - 159,170 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936692147,699 - 159,921 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
USP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6149,970,915 - 149,985,509 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16149,971,471 - 149,985,946 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
USP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12070,602,300 - 70,617,280 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2070,603,056 - 70,614,069 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603346,836,799 - 46,851,713 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Usp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474231,391,022 - 31,399,724 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474231,390,279 - 31,399,789 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Ensembl Acc Id: ENSPPAT00000032977   ⟹   ENSPPAP00000010327
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl163,510,196 - 63,525,446 (+)Ensembl
RefSeq Acc Id: XM_003809155   ⟹   XP_003809203
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21164,400,198 - 164,415,615 (-)NCBI
NHGRI_mPanPan11163,549,851 - 163,564,757 (-)NCBI
Mhudiblu_PPA_v0161,695,126 - 61,710,216 (+)NCBI
PanPan1.1163,510,196 - 63,525,446 (+)NCBI
Sequence:
RefSeq Acc Id: XM_003809156   ⟹   XP_003809204
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21164,400,198 - 164,417,233 (-)NCBI
NHGRI_mPanPan11163,549,851 - 163,565,593 (-)NCBI
Mhudiblu_PPA_v0161,694,775 - 61,710,216 (+)NCBI
PanPan1.1163,509,781 - 63,525,446 (+)NCBI
Sequence:
RefSeq Acc Id: XM_055091891   ⟹   XP_054947866
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21164,400,198 - 164,427,944 (-)NCBI
NHGRI_mPanPan11163,549,851 - 163,577,601 (-)NCBI
Protein RefSeqs XP_003809203 (Get FASTA)   NCBI Sequence Viewer  
  XP_003809204 (Get FASTA)   NCBI Sequence Viewer  
  XP_054947866 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000010327.1
RefSeq Acc Id: XP_003809204   ⟸   XM_003809156
- UniProtKB: A0A2R8ZZC2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003809203   ⟸   XM_003809155
- UniProtKB: A0A2R8ZZC2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000010327   ⟸   ENSPPAT00000032977
RefSeq Acc Id: XP_054947866   ⟸   XM_055091891
- UniProtKB: A0A2R8ZZC2 (UniProtKB/TrEMBL)
USP



1 to 19 of 19 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSPPAG00000028383 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000032977.1 UniProtKB/TrEMBL
Gene3D-CATH Cysteine proteinases UniProtKB/TrEMBL
InterPro Papain-like_cys_pep_sf UniProtKB/TrEMBL
  Peptidase_C19 UniProtKB/TrEMBL
  Peptidase_C19_UCH UniProtKB/TrEMBL
  USP1 UniProtKB/TrEMBL
  USP_CS UniProtKB/TrEMBL
  USP_dom UniProtKB/TrEMBL
KEGG Report pps:100982030 UniProtKB/TrEMBL
NCBI Gene USP1 ENTREZGENE
PANTHER UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UniProtKB/TrEMBL
  UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 1 UniProtKB/TrEMBL
Pfam UCH UniProtKB/TrEMBL
PROSITE USP_1 UniProtKB/TrEMBL
  USP_2 UniProtKB/TrEMBL
  USP_3 UniProtKB/TrEMBL
Superfamily-SCOP SSF54001 UniProtKB/TrEMBL
UniProt A0A2R8ZZC2 ENTREZGENE, UniProtKB/TrEMBL
1 to 19 of 19 rows