Itpr1 (inositol 1,4,5-trisphosphate receptor, type 1) - Rat Genome Database

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Gene: Itpr1 (inositol 1,4,5-trisphosphate receptor, type 1) Rattus norvegicus
Analyze
Symbol: Itpr1
Name: inositol 1,4,5-trisphosphate receptor, type 1
RGD ID: 2933
Description: Exhibits several functions, including inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; ion channel binding activity; and protein C-terminus binding activity. Involved in several processes, including cellular response to cAMP; liver regeneration; and positive regulation of hepatocyte proliferation. Localizes to several cellular components, including GABA-ergic synapse; endoplasmic reticulum; and postsynaptic density. Used to study asthma. Biomarker of Huntington's disease; cardiac arrest; and transient cerebral ischemia. Human ortholog(s) of this gene implicated in Gillespie syndrome; spinocerebellar ataxia type 15; and spinocerebellar ataxia type 29. Orthologous to human ITPR1 (inositol 1,4,5-trisphosphate receptor type 1); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: I145TR; inositol 1,4,5-triphosphate receptor 1; inositol 1,4,5-triphosphate receptor type 1; inositol 1,4,5-triphosphate receptor, type 1; inositol 1,4,5-trisphosphate receptor type 1; inositol 145-triphosphate receptor type 1; InsP3R; InsP3R1; IP-3-R; IP3 receptor; IP3R 1; IP3R1; P400; type 1 inositol 1,4,5-trisphosphate receptor; type 1 InsP3 receptor
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24141,187,377 - 141,554,240 (+)NCBI
Rnor_6.0 Ensembl4140,247,313 - 140,580,748 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.04140,247,297 - 140,580,749 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04204,714,729 - 205,047,901 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44143,705,360 - 144,030,051NCBIRGSC3.4rn4RGSC3.4
Celera4129,839,611 - 130,162,657 (+)NCBICelera
RH 3.4 Map4 RGD
Cytogenetic Map4q41NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
1D-myo-inositol 1,4,5-trisphosphate  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3',5-triiodo-L-thyronine  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
3-methylcholanthrene  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-diisothiocyano-trans-stilbene-2,2'-disulfonic acid  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-amino-2,6-dinitrotoluene  (EXP)
4-hydroxyphenyl retinamide  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
7,12-dimethyltetraphene  (ISO)
7,9-dihydro-1H-purine-2,6,8(3H)-trione  (ISO)
acetaldehyde  (ISO)
actinomycin D  (ISO)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
amphetamine  (EXP)
aristolochic acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bexarotene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bleomycin A5  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP)
caffeine  (ISO)
calcitriol  (ISO)
calcium atom  (ISO)
calcium(0)  (ISO)
carbon nanotube  (ISO)
clofibrate  (ISO)
cobalt dichloride  (EXP,ISO)
cocaine  (EXP,ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
cycloheximide  (ISO)
cypermethrin  (EXP)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP)
dicrotophos  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
emodin  (ISO)
endosulfan  (EXP)
Enterolactone  (ISO)
entinostat  (ISO)
ethanol  (ISO)
etoposide  (ISO)
fenvalerate  (ISO)
flavonoids  (EXP)
folic acid  (ISO)
fomepizole  (ISO)
formaldehyde  (ISO)
genistein  (ISO)
glyphosate  (ISO)
GW 4064  (ISO)
halothane  (ISO)
homocysteine  (ISO)
hydrogen peroxide  (ISO)
lead diacetate  (ISO)
lead(0)  (EXP)
lead(2+)  (EXP)
linsidomine  (ISO)
maneb  (ISO)
melatonin  (ISO)
methapyrilene  (EXP)
methotrexate  (ISO)
methylmercury chloride  (ISO)
methylseleninic acid  (ISO)
N-hexadecanoylsphingosine  (ISO)
nevirapine  (EXP)
nickel atom  (ISO)
O-methyleugenol  (ISO)
oxaliplatin  (EXP)
oxycodone  (EXP)
paracetamol  (ISO)
paraquat  (ISO)
PCB138  (EXP,ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
phenethyl caffeate  (ISO)
phenobarbital  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
pirinixic acid  (EXP,ISO)
potassium chloride  (EXP)
procaine  (ISO)
progesterone  (ISO)
propanal  (ISO)
propiconazole  (ISO)
pyrazinecarboxamide  (EXP)
quercetin  (ISO)
resveratrol  (ISO)
rotenone  (EXP)
sarin  (ISO)
SB 431542  (ISO)
scopolamine  (EXP)
silicon dioxide  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (EXP,ISO)
sodium dodecyl sulfate  (ISO)
Soman  (EXP)
succimer  (ISO)
sulindac sulfide  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
tauroursodeoxycholic acid  (ISO)
testosterone  (ISO)
thapsigargin  (ISO)
thioacetamide  (EXP)
toluene  (EXP)
topiramate  (EXP)
topotecan  (EXP)
trichostatin A  (ISO)
urethane  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (EXP)
vincristine  (ISO)
vorinostat  (ISO)
xestospongin C  (ISO)
XL147  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
acebutolol pharmacodynamics pathway  (ISO)
adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway  (ISO)
Alzheimer's disease pathway  (IEA)
amiodarone pharmacodynamics pathway  (ISO)
amlodipine pharmacodynamics pathway  (ISO)
atenolol pharmacodynamics pathway  (ISO)
betaxolol pharmacodynamics pathway  (ISO)
bisoprolol pharmacodynamics pathway  (ISO)
bupranolol drug pathway  (ISO)
bupranolol pharmacodynamics pathway  (ISO)
calcium transport pathway  (ISO)
calcium/calcium-mediated signaling pathway  (IEA,ISO)
carvedilol pharmacodynamics pathway  (ISO)
diltiazem pharmacodynamics pathway  (ISO)
disopyramide pharmacodynamics pathway  (ISO)
dobutamine pharmacodynamics pathway  (ISO)
esmolol pharmacodynamics pathway  (ISO)
flecainde pharmacodynamics pathway  (ISO)
fosphenytoin pharmacodynamics pathway  (ISO)
glutamate signaling pathway  (IEA)
gonadotropin-releasing hormone signaling pathway  (IEA)
Huntington's disease pathway  (IEA)
ibutilide pharmacodynamics pathway  (ISO)
isoprenaline pharmacodynamics pathway  (ISO)
isradipine pharmacodynamics pathway  (ISO)
levobunolol pharmacodynamics pathway  (ISO)
lidocaine pharmacodynamics pathway  (ISO)
long term depression  (IEA)
long term potentiation  (IEA)
metoprolol pharmacodynamics pathway  (ISO)
mexiletine pharmacodynamics pathway  (ISO)
nadolol pharmacodynamics pathway  (ISO)
nebivolol pharmacodynamics pathway  (ISO)
nifedipine pharmacodynamics pathway  (ISO)
nimodipine pharmacodynamics pathway  (ISO)
nisoldipine pharmacodynamics pathway  (ISO)
nitrendipine pharmacodynamics pathway  (ISO)
penbutolol pharmacodynamics pathway  (ISO)
phenytoin pharmacodynamics pathway  (ISO)
phosphatidylinositol 3-kinase signaling pathway  (IEA)
pindolol pharmacodynamics pathway  (ISO)
procainamide pharmacodynamics pathway  (ISO)
propranolol pharmacodynamics pathway  (ISO)
quinidine pharmacodynamics pathway  (ISO)
sotalol pharmacodynamics pathway  (ISO)
timolol pharmacodynamics pathway  (ISO)
verapamil pharmacodynamics pathway  (ISO)

References

References - curated
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4. Bickler PE and Fahlman CS, Brain Res. 2010 Jun 22;1340:86-95. Epub 2010 Apr 29.
5. Cardenas C, etal., J Cell Sci. 2005 Jul 15;118(Pt 14):3131-40.
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11. Fan G, etal., Nature. 2015 Nov 19;527(7578):336-41. doi: 10.1038/nature15249. Epub 2015 Oct 12.
12. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
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14. GOA data from the GO Consortium
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16. Haug LS, etal., Neurodegeneration. 1996 Jun;5(2):169-76.
17. Higo T, etal., Neuron. 2010 Dec 9;68(5):865-78.
18. Hirata K, etal., Hepatology 2002 Aug;36(2):284-96.
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20. Ikebara JM, etal., PLoS One. 2017 Jan 10;12(1):e0169861. doi: 10.1371/journal.pone.0169861. eCollection 2017.
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23. Jurkovicova D, etal., Pflugers Arch. 2007 Jun;454(3):415-25. Epub 2007 Feb 7.
24. Kajimoto K, etal., Biochem Pharmacol 2003 Mar 15;65(6):995-8.
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26. Kozaki Y, etal., J Physiol Sci. 2015 Sep;65(5):417-25. doi: 10.1007/s12576-015-0380-9. Epub 2015 May 14.
27. Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
28. Lee B, etal., Endocrinology 2001 May;142(5):1744-51.
29. Lee HP, etal., Neuroscience. 2010 May 19;167(3):799-808. Epub 2010 Feb 26.
30. Lencesova L, etal., FEBS Lett 2002 Nov 20;531(3):432-6.
31. Li M, etal., J Inflamm (Lond). 2011 Jul 21;8(1):18.
32. Li Y, etal., J Biol Chem. 2005 Dec 16;280(50):41298-306. Epub 2005 Oct 13.
33. Ludtke SJ, etal., Structure. 2011 Aug 10;19(8):1192-9. doi: 10.1016/j.str.2011.05.003.
34. Marelli C, etal., Arch Neurol. 2011 May;68(5):637-43.
35. Matsumoto M and Nagata E, J Mol Med (Berl). 1999 May;77(5):406-11.
36. Maximov A, etal., Mol Cell Neurosci. 2003 Feb;22(2):271-83.
37. MGD data from the GO Consortium
38. Mignery GA, etal., J Biol Chem 1990 Jul 25;265(21):12679-85.
39. NCBI rat LocusLink and RefSeq merged data July 26, 2002
40. Nicolay NH, etal., J Neurosci Res. 2007 Jul;85(9):2026-36.
41. Oliveira AG, etal., Liver Int. 2015 Apr;35(4):1162-71. doi: 10.1111/liv.12587. Epub 2014 Jun 2.
42. Olson TM and Keating MT, J Clin Invest 1996 Jan 15;97(2):528-32.
43. OMIM Disease Annotation Pipeline
44. Pipeline to import KEGG annotations from KEGG into RGD
45. Pipeline to import SMPDB annotations from SMPDB into RGD
46. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
47. RGD automated import pipeline for gene-chemical interactions
48. Smutzer G, etal., Brain Res Mol Brain Res 1997 Mar;44(2):347-54.
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50. Takei K, etal., J Neurosci. 1992 Feb;12(2):489-505.
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54. Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
55. Tovey SC, etal., J Biol Chem. 2010 Apr 23;285(17):12979-89. doi: 10.1074/jbc.M109.096016. Epub 2010 Feb 26.
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Additional References at PubMed
PMID:8663526   PMID:8889548   PMID:9716504   PMID:9858485   PMID:10191279   PMID:10506212   PMID:10828023   PMID:11117745   PMID:11285228   PMID:11587548   PMID:11972451   PMID:12167631  
PMID:12477932   PMID:12617961   PMID:12820984   PMID:14517800   PMID:14593108   PMID:14982933   PMID:15364918   PMID:15579147   PMID:15613488   PMID:15739177   PMID:15774532   PMID:15843050  
PMID:16118475   PMID:16198415   PMID:16223514   PMID:16237118   PMID:16377004   PMID:16691292   PMID:16723353   PMID:16793548   PMID:16840702   PMID:17284437   PMID:17327232   PMID:17416589  
PMID:17496801   PMID:17502376   PMID:17590087   PMID:17636122   PMID:18799650   PMID:18835357   PMID:18955483   PMID:19120137   PMID:19141613   PMID:19292454   PMID:19386591   PMID:19752026  
PMID:19845505   PMID:19934645   PMID:19946888   PMID:20378853   PMID:20713546   PMID:20813840   PMID:21071436   PMID:21098487   PMID:21389686   PMID:22207335   PMID:22286060   PMID:22762283  
PMID:22871113   PMID:23009366   PMID:23045459   PMID:23137780   PMID:23542070   PMID:23555994   PMID:23650371   PMID:24097979   PMID:25201980   PMID:25262337   PMID:25368151   PMID:28336440  
PMID:28526746   PMID:28923351   PMID:29476059   PMID:30053369   PMID:30090007   PMID:30470765  


Genomics

Candidate Gene Status
Itpr1 is a candidate Gene for QTL Bp116
Comparative Map Data
Itpr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24141,187,377 - 141,554,240 (+)NCBI
Rnor_6.0 Ensembl4140,247,313 - 140,580,748 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.04140,247,297 - 140,580,749 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04204,714,729 - 205,047,901 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44143,705,360 - 144,030,051NCBIRGSC3.4rn4RGSC3.4
Celera4129,839,611 - 130,162,657 (+)NCBICelera
RH 3.4 Map4 RGD
Cytogenetic Map4q41NCBI
ITPR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl34,493,345 - 4,847,506 (+)EnsemblGRCh38hg38GRCh38
GRCh3834,493,348 - 4,847,506 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3734,535,032 - 4,889,190 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3634,510,034 - 4,864,286 (+)NCBINCBI36hg18NCBI36
Build 3434,510,135 - 4,864,079NCBI
Celera34,473,120 - 4,827,522 (+)NCBI
Cytogenetic Map3p26.1NCBI
HuRef34,468,779 - 4,822,934 (+)NCBIHuRef
CHM1_134,485,103 - 4,839,760 (+)NCBICHM1_1
Itpr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396108,190,044 - 108,528,077 (+)NCBIGRCm39mm39
GRCm39 Ensembl6108,190,057 - 108,528,070 (+)Ensembl
GRCm386108,213,083 - 108,551,116 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6108,213,096 - 108,551,109 (+)EnsemblGRCm38mm10GRCm38
MGSCv376108,163,090 - 108,501,108 (+)NCBIGRCm37mm9NCBIm37
MGSCv366108,178,895 - 108,516,886 (+)NCBImm8
Celera6110,018,018 - 110,348,287 (+)NCBICelera
Cytogenetic Map6E1- E2NCBI
cM Map649.74NCBI
ITPR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.134,549,775 - 4,904,811 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl34,572,921 - 4,904,811 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v034,448,574 - 4,802,545 (+)NCBIMhudiblu_PPA_v0panPan3
ITPR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12012,746,171 - 13,065,256 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2012,747,315 - 13,064,198 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2012,719,920 - 13,038,750 (-)NCBI
ROS_Cfam_1.02012,789,247 - 13,108,309 (-)NCBI
UMICH_Zoey_3.12012,494,231 - 12,813,462 (-)NCBI
UNSW_CanFamBas_1.02012,835,196 - 13,153,754 (-)NCBI
UU_Cfam_GSD_1.02012,821,769 - 13,140,816 (-)NCBI
Itpr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494210,941,137 - 11,243,016 (+)NCBI
SpeTri2.0NW_0049365773,896,455 - 4,198,396 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ITPR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1361,068,126 - 61,398,908 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11361,068,131 - 61,398,918 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21367,499,295 - 67,702,956 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ITPR1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12240,574,569 - 40,925,857 (+)NCBI
ChlSab1.1 Ensembl2240,574,374 - 40,926,842 (+)Ensembl
Vero_WHO_p1.0NW_023666041125,743,247 - 126,095,217 (-)NCBI
Itpr1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462477314,856,803 - 15,193,173 (+)NCBI

Position Markers
D4Rat195  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24141,356,262 - 141,356,570 (+)MAPPER
mRatBN7.24141,356,262 - 141,356,469 (+)MAPPER
Rnor_6.04140,425,986 - 140,426,192NCBIRnor6.0
Rnor_6.04140,425,986 - 140,426,293NCBIRnor6.0
Rnor_5.04204,893,198 - 204,893,404UniSTSRnor5.0
Rnor_5.04204,893,198 - 204,893,505UniSTSRnor5.0
RGSC_v3.44143,875,116 - 143,875,322UniSTSRGSC3.4
RGSC_v3.44143,875,116 - 143,875,423UniSTSRGSC3.4
RGSC_v3.44143,875,115 - 143,875,322RGDRGSC3.4
RGSC_v3.14144,119,957 - 144,120,163RGD
Celera4130,008,518 - 130,008,825UniSTS
Celera4130,008,518 - 130,008,724UniSTS
RH 3.4 Map4890.8RGD
RH 3.4 Map4890.8UniSTS
RH 2.0 Map4897.9RGD
SHRSP x BN Map465.6899RGD
Cytogenetic Map4q41UniSTS
D4Rat196  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24141,235,569 - 141,235,720 (+)MAPPER
Rnor_6.04140,295,371 - 140,295,521NCBIRnor6.0
Rnor_5.04204,762,862 - 204,763,012UniSTSRnor5.0
RGSC_v3.44143,753,495 - 143,753,646RGDRGSC3.4
RGSC_v3.44143,753,496 - 143,753,646UniSTSRGSC3.4
RGSC_v3.14143,998,336 - 143,998,487RGD
Celera4129,887,354 - 129,887,504UniSTS
SHRSP x BN Map465.65RGD
SHRSP x BN Map465.65UniSTS
Cytogenetic Map4q41UniSTS
D4Got259  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24141,480,540 - 141,480,804 (+)MAPPER
Rnor_6.04140,550,598 - 140,550,861NCBIRnor6.0
Rnor_5.04205,017,750 - 205,018,013UniSTSRnor5.0
RGSC_v3.44144,000,102 - 144,000,365UniSTSRGSC3.4
Celera4130,132,792 - 130,133,055UniSTS
Cytogenetic Map4q41UniSTS
RH133754  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24141,322,729 - 141,322,910 (+)MAPPER
Rnor_6.04140,382,763 - 140,382,943NCBIRnor6.0
Rnor_5.04204,850,254 - 204,850,434UniSTSRnor5.0
RGSC_v3.44143,841,369 - 143,841,549UniSTSRGSC3.4
Celera4129,974,518 - 129,974,698UniSTS
RH 3.4 Map4885.6UniSTS
Cytogenetic Map4q41UniSTS
RH94529  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24141,510,212 - 141,510,376 (+)MAPPER
Rnor_6.04140,580,470 - 140,580,633NCBIRnor6.0
Rnor_5.04205,047,622 - 205,047,785UniSTSRnor5.0
RGSC_v3.44144,029,773 - 144,029,936UniSTSRGSC3.4
Celera4130,162,378 - 130,162,541UniSTS
RH 3.4 Map4890.9UniSTS
Cytogenetic Map4q41UniSTS
RH140203  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24141,509,945 - 141,510,139 (+)MAPPER
Rnor_6.04140,580,203 - 140,580,396NCBIRnor6.0
Rnor_5.04205,047,355 - 205,047,548UniSTSRnor5.0
RGSC_v3.44144,029,506 - 144,029,699UniSTSRGSC3.4
Celera4130,162,111 - 130,162,304UniSTS
RH 3.4 Map4886.7UniSTS
Cytogenetic Map4q41UniSTS
AU048843  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24141,306,952 - 141,307,250 (+)MAPPER
Rnor_6.04140,366,986 - 140,367,283NCBIRnor6.0
Rnor_5.04204,834,477 - 204,834,774UniSTSRnor5.0
RGSC_v3.44143,825,377 - 143,825,674UniSTSRGSC3.4
Celera4129,958,745 - 129,959,042UniSTS
Cytogenetic Map4q41UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)47850904182171018Rat
731165Uae21Urinary albumin excretion QTL 212.40.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)4106347236151347236Rat
737821Hcar9Hepatocarcinoma resistance QTL 93.7liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)4105971071168047091Rat
1298082Stresp4Stress response QTL 4blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)446898276145611886Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)463537179157286626Rat
631683Bp116Blood pressure QTL 1160.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4123111827168111827Rat
737978Pia23Pristane induced arthritis QTL 235.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4131532269168047091Rat
6478760Anxrr45Anxiety related response QTL 450.06717locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4110702761155702761Rat
6478763Anxrr46Anxiety related response QTL 460.07428locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4110702761155702761Rat
6478778Anxrr51Anxiety related response QTL 510.25384locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4123587009168587009Rat
1298524Oia8Oil induced arthritis QTL 8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4136351734174694858Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)458640017154427984Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)458640017154427984Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)458640017154427984Rat
631511Pia7Pristane induced arthritis QTL 74.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4131532269168047091Rat
634347Hcar8Hepatocarcinoma resistance QTL 85.8liver integrity trait (VT:0010547)liver tumorous lesion area to total liver area ratio (CMO:0001075)4123478354168478354Rat
7411558Bw133Body weight QTL 13313.840.001body mass (VT:0001259)body weight gain (CMO:0000420)4124442168169442168Rat
7207480Bss105Bone structure and strength QTL 1058.1femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)4109636356154636356Rat
1300116Hrtrt5Heart rate QTL 53.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)4115372758150038284Rat
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)436615599145611886Rat
1358364Sradr4Stress Responsive Adrenal Weight QTL 44.92adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)4128602727173602727Rat
1331738Bp209Blood pressure QTL 2092.979arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)4136351734180689124Rat
1331802Srn5Serum renin concentration QTL 53.045renin activity (VT:0005581)plasma renin activity level (CMO:0000116)4116726724157291438Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)443414792146942075Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)443414792146942075Rat
1358202Gluco11Glucose level QTL 112.40.02adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)486438317168047091Rat
1549827Scl46Serum cholesterol level QTL 463.5blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)4131864442176864442Rat
1549832Bss3Bone structure and strength QTL 311femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)4109636356154636356Rat
1582232Gluco25Glucose level QTL 253.60.0023blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)486312589146942261Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)443414605155469929Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)484475257178931073Rat
1578674Bmd12Bone mineral density QTL 123.8femur mineral mass (VT:0010011)cortical volumetric bone mineral density (CMO:0001730)4137171018182171018Rat
61362Oia2Oil induced arthritis QTL 20.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4136351734174694858Rat
61406Scwia1Streptococcal cell wall induced arthritis QTL 12.3joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)4105682594150682594Rat
61422Cia13Collagen induced arthritis QTL 134.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4132455408168047091Rat
61434Cia3Collagen induced arthritis QTL 34.8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)499066823144066823Rat
70177Xhs1X-ray hypersensitivity QTL 125.1intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)481959983152055009Rat
70200Alc18Alcohol consumption QTL 189.2drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)455324953148360954Rat
724558Plsm2Polydactyly-luxate syndrome (PLS) morphotypes QTL 20.0003hindlimb integrity trait (VT:0010563)hind foot phalanges count (CMO:0001949)4131834282176834282Rat
2293840Kiddil9Kidney dilation QTL 92.9kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)4120400597146942261Rat
2302049Pia32Pristane induced arthritis QTL 325.10.001blood autoantibody amount (VT:0003725)serum immunoglobulin G-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002112)4105277348150277348Rat
2303623Vencon2Ventilatory control QTL 23.8respiration trait (VT:0001943)minute ventilation (CMO:0000132)4134917642179917642Rat
634335Anxrr16Anxiety related response QTL 167.22locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)494893247168046938Rat
70201Gcr1Gastric cancer resistance QTL 12.7stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)4119705414146087100Rat
12798523Anxrr56Anxiety related response QTL 562.830.05locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)486312589147702403Rat
724535Cm18Cardiac mass QTL 182.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)4117926139162926139Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)43043231145254791Rat
12798527Anxrr58Anxiety related response QTL 584.110.05locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4120318422146087100Rat
2312567Glom19Glomerulus QTL 191.90.006kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)449906054145611886Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)423850384169318094Rat
12798519Anxrr54Anxiety related response QTL 542.540.05locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4112807675157807675Rat
61451Ciaa4CIA Autoantibody QTL 43.1blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)4125884464168047091Rat
1331759Hrtrt13Heart rate QTL 133.54628heart pumping trait (VT:2000009)heart rate (CMO:0000002)4108876717169215811Rat
2293659Bmd35Bone mineral density QTL 354.50.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)4136908430182878540Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2097
Count of miRNA genes:288
Interacting mature miRNAs:363
Transcripts:ENSRNOT00000040255, ENSRNOT00000041130, ENSRNOT00000043646, ENSRNOT00000064025
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 38 28 12 19 12 8 8 43 35 33 11 8
Low 1 5 29 29 29 3 31 8
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001007235 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001270596 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001270597 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006236987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008763167 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008763168 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008763169 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008763170 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008763171 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008763172 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008763173 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008763174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008763175 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008763176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008763177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008763178 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107092 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107094 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107098 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107099 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107101 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC091346 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BF402715 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473957 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225812 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233552 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GQ233032 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  J05510 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000148 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M64698 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M64699 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U38653 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U38665 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U38812 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000040255   ⟹   ENSRNOP00000043615
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl4140,247,313 - 140,579,675 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000041130   ⟹   ENSRNOP00000049540
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl4140,247,335 - 140,580,748 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000043646   ⟹   ENSRNOP00000048661
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl4140,247,335 - 140,580,748 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000064025   ⟹   ENSRNOP00000063885
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl4140,247,335 - 140,580,748 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000082723   ⟹   ENSRNOP00000075403
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl4140,377,565 - 140,579,477 (+)Ensembl
RefSeq Acc Id: NM_001007235   ⟹   NP_001007236
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24141,187,418 - 141,510,492 (+)NCBI
Rnor_6.04140,247,335 - 140,580,749 (+)NCBI
Rnor_5.04204,714,729 - 205,047,901 (+)NCBI
RGSC_v3.44143,705,360 - 144,030,051 (+)RGD
Celera4129,839,611 - 130,162,657 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001270596   ⟹   NP_001257525
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24141,187,418 - 141,510,492 (+)NCBI
Rnor_6.04140,247,335 - 140,580,749 (+)NCBI
Rnor_5.04204,714,729 - 205,047,901 (+)NCBI
Celera4129,839,611 - 130,162,657 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001270597   ⟹   NP_001257526
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24141,187,418 - 141,510,492 (+)NCBI
Rnor_6.04140,247,335 - 140,580,749 (+)NCBI
Rnor_5.04204,714,729 - 205,047,901 (+)NCBI
Celera4129,839,611 - 130,162,657 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006236987   ⟹   XP_006237049
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24141,187,378 - 141,510,492 (+)NCBI
Rnor_6.04140,247,297 - 140,580,749 (+)NCBI
Rnor_5.04204,714,729 - 205,047,901 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008763167   ⟹   XP_008761389
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04140,248,102 - 140,580,749 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008763168   ⟹   XP_008761390
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04140,248,102 - 140,580,749 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008763169   ⟹   XP_008761391
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04140,248,102 - 140,580,749 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008763170   ⟹   XP_008761392
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04140,248,102 - 140,580,749 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008763171   ⟹   XP_008761393
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04140,248,102 - 140,580,749 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008763172   ⟹   XP_008761394
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04140,248,102 - 140,580,749 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008763173   ⟹   XP_008761395
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04140,248,102 - 140,580,749 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008763174   ⟹   XP_008761396
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04140,248,102 - 140,580,749 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008763175   ⟹   XP_008761397
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04140,248,102 - 140,580,749 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008763176   ⟹   XP_008761398
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04140,248,102 - 140,580,749 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008763177   ⟹   XP_008761399
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04140,248,102 - 140,580,749 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008763178   ⟹   XP_008761400
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04140,248,102 - 140,580,749 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039107092   ⟹   XP_038963020
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24141,187,378 - 141,510,492 (+)NCBI
RefSeq Acc Id: XM_039107093   ⟹   XP_038963021
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24141,187,378 - 141,510,492 (+)NCBI
RefSeq Acc Id: XM_039107094   ⟹   XP_038963022
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24141,187,377 - 141,554,240 (+)NCBI
RefSeq Acc Id: XM_039107095   ⟹   XP_038963023
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24141,187,378 - 141,510,492 (+)NCBI
RefSeq Acc Id: XM_039107096   ⟹   XP_038963024
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24141,187,378 - 141,510,492 (+)NCBI
RefSeq Acc Id: XM_039107097   ⟹   XP_038963025
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24141,187,378 - 141,510,492 (+)NCBI
RefSeq Acc Id: XM_039107098   ⟹   XP_038963026
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24141,187,378 - 141,510,492 (+)NCBI
RefSeq Acc Id: XM_039107099   ⟹   XP_038963027
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24141,187,379 - 141,510,492 (+)NCBI
RefSeq Acc Id: XM_039107100   ⟹   XP_038963028
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24141,187,378 - 141,510,492 (+)NCBI
RefSeq Acc Id: XM_039107101   ⟹   XP_038963029
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24141,187,379 - 141,510,492 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_001007236   ⟸   NM_001007235
- Peptide Label: isoform 1
- UniProtKB: C7E1V2 (UniProtKB/TrEMBL),   Q5BJS8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001257526   ⟸   NM_001270597
- Peptide Label: isoform 3
- UniProtKB: P29994 (UniProtKB/Swiss-Prot),   C7E1V2 (UniProtKB/TrEMBL),   Q5BJS8 (UniProtKB/TrEMBL),   A0A0A0MY31 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001257525   ⟸   NM_001270596
- Peptide Label: isoform 2
- UniProtKB: C7E1V2 (UniProtKB/TrEMBL),   F1LQX8 (UniProtKB/TrEMBL),   Q5BJS8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006237049   ⟸   XM_006236987
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_008761389   ⟸   XM_008763167
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_008761390   ⟸   XM_008763168
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_008761391   ⟸   XM_008763169
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_008761392   ⟸   XM_008763170
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_008761393   ⟸   XM_008763171
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_008761394   ⟸   XM_008763172
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_008761396   ⟸   XM_008763174
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_008761395   ⟸   XM_008763173
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_008761399   ⟸   XM_008763177
- Peptide Label: isoform X11
- Sequence:
RefSeq Acc Id: XP_008761397   ⟸   XM_008763175
- Peptide Label: isoform X9
- Sequence:
RefSeq Acc Id: XP_008761398   ⟸   XM_008763176
- Peptide Label: isoform X10
- Sequence:
RefSeq Acc Id: XP_008761400   ⟸   XM_008763178
- Peptide Label: isoform X12
- Sequence:
RefSeq Acc Id: ENSRNOP00000075403   ⟸   ENSRNOT00000082723
RefSeq Acc Id: ENSRNOP00000049540   ⟸   ENSRNOT00000041130
RefSeq Acc Id: ENSRNOP00000048661   ⟸   ENSRNOT00000043646
RefSeq Acc Id: ENSRNOP00000043615   ⟸   ENSRNOT00000040255
RefSeq Acc Id: ENSRNOP00000063885   ⟸   ENSRNOT00000064025
RefSeq Acc Id: XP_038963022   ⟸   XM_039107094
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038963020   ⟸   XM_039107092
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038963023   ⟸   XM_039107095
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038963024   ⟸   XM_039107096
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038963021   ⟸   XM_039107093
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038963025   ⟸   XM_039107097
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038963028   ⟸   XM_039107100
- Peptide Label: isoform X10
RefSeq Acc Id: XP_038963026   ⟸   XM_039107098
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038963027   ⟸   XM_039107099
- Peptide Label: isoform X9
RefSeq Acc Id: XP_038963029   ⟸   XM_039107101
- Peptide Label: isoform X11
Protein Domains
MIR

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693288
Promoter ID:EPDNEW_R3807
Type:single initiation site
Name:Itpr1_1
Description:inositol 1,4,5-trisphosphate receptor, type 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04140,247,229 - 140,247,289EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2933 AgrOrtholog
Ensembl Genes ENSRNOG00000007104 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000043615 UniProtKB/TrEMBL
  ENSRNOP00000048661 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000049540 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000063885 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000075403 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000040255 UniProtKB/TrEMBL
  ENSRNOT00000041130 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000043646 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000064025 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000082723 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7316579 IMAGE-MGC_LOAD
InterPro ARM-type_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ins145_P3_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  InsP3_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ion_trans_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MIR_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MIR_motif UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RIH_assoc-dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RIH_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RyR/IP3R_RIH_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:25262 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:109369 IMAGE-MGC_LOAD
NCBI Gene 25262 ENTREZGENE
Pfam Ins145_P3_rec UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ion_trans UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MIR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RIH_assoc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RYDR_ITPR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB ITPR1 RGD
PhenoGen Itpr1 PhenoGen
PRINTS INSP3RECEPTR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE MIR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART MIR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF100909 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF48371 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF82109 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC228573
UniProt A0A0A0MY31 ENTREZGENE, UniProtKB/TrEMBL
  A0A0G2KAH9_RAT UniProtKB/TrEMBL
  C7E1V2 ENTREZGENE, UniProtKB/TrEMBL
  F1LNT1_RAT UniProtKB/TrEMBL
  F1LQX8 ENTREZGENE, UniProtKB/TrEMBL
  ITPR1_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q5BJS8 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary F1LQS8 UniProtKB/TrEMBL
  Q62869 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-08-02 Itpr1  inositol 1,4,5-trisphosphate receptor, type 1  Itpr1  inositol 1,4,5-triphosphate receptor, type 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-11-17 Itpr1  inositol 1,4,5-triphosphate receptor, type 1  Itpr1  inositol 1,4,5-triphosphate receptor 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2003-04-09 Itpr1  inositol 1,4,5-triphosphate receptor 1    inositol 1,4,5-triphosphate receptor type 1  Name updated 629478 APPROVED
2002-06-10 Itpr1  inositol 1,4,5-triphosphate receptor type 1      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_process mobilizes calcium ion permeability in insulin secreting cells 68695
gene_process plays a role in insulin secretion 68695
gene_regulation down regulated in response to muscarinic receptor activation by carbachol 68695
gene_transcript has two alternative splicing forms which are differentially expressed in a neuronal and non-neuronal manner 729259