Dera (deoxyribose-phosphate aldolase)

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Gene: Dera (deoxyribose-phosphate aldolase) Rattus norvegicus

Analyze

Symbol:

Dera

Name:

deoxyribose-phosphate aldolase

RGD ID:

1589836

Description:

Predicted to enable deoxyribose-phosphate aldolase activity. Predicted to be involved in carbohydrate catabolic process; deoxyribonucleoside catabolic process; and deoxyribonucleotide catabolic process. Predicted to be located in nucleoplasm. Orthologous to human DERA (deoxyribose-phosphate aldolase); PARTICIPATES IN pentose phosphate pathway; ribose 5-phosphate isomerase deficiency pathway; transaldolase deficiency pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; aconitine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

2-deoxyribose-5-phosphate aldolase homolog; 2-deoxyribose-5-phosphate aldolase homolog (C. elegans); 2-deoxyribose-5-phosphate aldolase homolog (C. elegans), pseudogene 1; 2-deoxyribose-5-phosphate aldolase homolog, pseudogene 1; deoxyribose-phosphate aldolase (putative); deoxyribose-phosphate aldolase, pseudogene 1; Dera-ps1; LOC690945; similar to Putative deoxyribose-phosphate aldolase (Phosphodeoxyriboaldolase) (Deoxyriboaldolase) (DERA)

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	DERA (deoxyribose-phosphate aldolase)	RGD	RGD
Mus musculus (house mouse):	Dera (deoxyribose-phosphate aldolase (putative))	RGD	RGD
Chinchilla lanigera (long-tailed chinchilla):	Dera (deoxyribose-phosphate aldolase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	DERA (deoxyribose-phosphate aldolase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	DERA (deoxyribose-phosphate aldolase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Dera (deoxyribose-phosphate aldolase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	DERA (deoxyribose-phosphate aldolase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	DERA (deoxyribose-phosphate aldolase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Dera (deoxyribose-phosphate aldolase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	DERA (deoxyribose-phosphate aldolase)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Dera (deoxyribose-phosphate aldolase (putative))	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	dera (deoxyribose-phosphate aldolase (putative))	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	F09E5.3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG8525	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	4	170,663,646 - 170,742,469 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	170,663,665 - 170,758,865 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	4	176,958,855 - 177,037,536 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	4	172,743,186 - 172,821,868 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	4	171,363,565 - 171,442,248 (+)	NCBI	Rnor_WKY
Rnor_6.0	4	171,748,254 - 171,826,414 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	171,748,273 - 171,826,409 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	236,005,130 - 236,082,656 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	174,881,147 - 174,960,828 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	4	159,239,888 - 159,318,620 (+)	NCBI		Celera
Cytogenetic Map	4	q44	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

COVID-19 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

17beta-estradiol (ISO)

2,3',4,4',5-Pentachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

4,4'-sulfonyldiphenol (ISO)

aconitine (EXP)

aflatoxin B1 (ISO)

aristolochic acid A (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

biochanin A (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

captan (ISO)

carbon nanotube (ISO)

cisplatin (ISO)

cobalt dichloride (ISO)

coumestrol (ISO)

cyclosporin A (ISO)

dexamethasone (ISO)

dibutyl phthalate (EXP)

dicrotophos (ISO)

diuron (EXP)

elemental selenium (ISO)

Enterolactone (ISO)

ethyl methanesulfonate (ISO)

fenthion (ISO)

folic acid (ISO)

folpet (ISO)

fulvestrant (ISO)

glafenine (EXP)

ivermectin (ISO)

leflunomide (ISO)

methidathion (ISO)

methyl methanesulfonate (ISO)

naphthalene (ISO)

ozone (ISO)

paracetamol (EXP,ISO)

phenobarbital (ISO)

resveratrol (ISO)

rotenone (ISO)

selenium atom (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

temozolomide (ISO)

tetrachloromethane (EXP,ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

trimellitic anhydride (ISO)

urethane (ISO)

valproic acid (ISO)

vincaleukoblastine (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

carbohydrate catabolic process (IBA)

deoxyribonucleoside catabolic process (ISO)

deoxyribonucleotide catabolic process (IBA)

deoxyribose phosphate catabolic process (IEA)

Cellular Component

cellular_component (ND)

cytoplasm (IEA)

nucleoplasm (ISO)

Molecular Function

deoxyribose-phosphate aldolase activity (IBA,ISO)

molecular_function (ND)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

pentose phosphate pathway (ISO)

ribose 5-phosphate isomerase deficiency pathway (ISO)

transaldolase deficiency pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	SMPDB Annotation Import Pipeline	Pipeline to import SMPDB annotations from SMPDB into RGD
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
5.	Comprehensive gene review and curation	RGD comprehensive gene curation

Additional References at PubMed

PMID:9226884	PMID:23376485	PMID:31505169

Genomics

Comparative Map Data

Dera
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	4	170,663,646 - 170,742,469 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	170,663,665 - 170,758,865 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	4	176,958,855 - 177,037,536 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	4	172,743,186 - 172,821,868 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	4	171,363,565 - 171,442,248 (+)	NCBI	Rnor_WKY
Rnor_6.0	4	171,748,254 - 171,826,414 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	171,748,273 - 171,826,409 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	236,005,130 - 236,082,656 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	174,881,147 - 174,960,828 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	4	159,239,888 - 159,318,620 (+)	NCBI		Celera
Cytogenetic Map	4	q44	NCBI

DERA
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	15,911,332 - 16,037,381 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	12	15,911,302 - 16,037,381 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	12	16,064,266 - 16,190,315 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	15,955,453 - 16,081,582 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	12	15,955,549 - 16,081,478	NCBI
Celera	12	21,209,100 - 21,335,267 (+)	NCBI		Celera
Cytogenetic Map	12	p12.3	NCBI
HuRef	12	15,833,389 - 15,959,597 (+)	NCBI		HuRef
CHM1_1	12	16,030,127 - 16,156,272 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	12	15,788,590 - 15,914,666 (+)	NCBI		T2T-CHM13v2.0

Dera
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	137,731,093 - 137,814,894 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	137,731,544 - 137,834,338 (+)	Ensembl		GRCm39 Ensembl
GRCm38	6	137,754,577 - 137,837,872 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	137,754,546 - 137,857,340 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	137,703,098 - 137,786,393 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	6	137,718,773 - 137,802,068 (+)	NCBI		MGSCv36	mm8
Celera	6	140,820,521 - 140,904,146 (+)	NCBI		Celera
Cytogenetic Map	6	G1	NCBI

Dera
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955413	12,571,176 - 12,685,852 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955413	12,571,341 - 12,682,985 (+)	NCBI	ChiLan1.0	ChiLan1.0

DERA
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	12	16,308,938 - 16,433,927 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	16,308,938 - 16,433,916 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	12	15,912,337 - 16,037,778 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

DERA
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	27	30,675,225 - 30,741,202 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	27	30,675,247 - 30,817,388 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	27	15,655,878 - 15,773,298 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	27	30,994,487 - 31,111,963 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	27	30,992,054 - 31,111,933 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	27	30,885,023 - 31,002,386 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	27	30,839,662 - 30,957,127 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	27	15,378,197 - 15,495,659 (+)	NCBI		UU_Cfam_GSD_1.0

Dera
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	91,827,965 - 91,937,587 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936587	1,555,531 - 1,665,289 (-)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936587	1,555,534 - 1,665,217 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

DERA
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	56,590,980 - 56,706,458 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	5	56,590,982 - 56,706,479 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	59,878,455 - 59,995,841 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

DERA
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	15,819,678 - 15,947,137 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	15,819,708 - 15,947,159 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666069	19,353,060 - 19,480,500 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Dera
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624752	22,031,023 - 22,133,821 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624752	22,031,094 - 22,133,771 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Dera
358 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	285
Count of miRNA genes:	177
Interacting mature miRNAs:	207
Transcripts:	ENSRNOT00000009998
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2316958	Gluco58	Glucose level QTL 58	10		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	4	11320076	180699135	Rat
1576316	Ept5	Estrogen-induced pituitary tumorigenesis QTL 5	3.8		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	4	83428419	177635233	Rat
1549827	Scl46	Serum cholesterol level QTL 46	3.5		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	4	132396220	177396220	Rat
724558	Plsm2	Polydactyly-luxate syndrome (PLS) morphotypes QTL 2		0.0003	hindlimb integrity trait (VT:0010563)	hind foot phalanges count (CMO:0001949)	4	132422778	177422778	Rat
2303623	Vencon2	Ventilatory control QTL 2	3.8		respiration trait (VT:0001943)	minute ventilation (CMO:0000132)	4	135204660	180204660	Rat
1578674	Bmd12	Bone mineral density QTL 12	3.8		femur mineral mass (VT:0010011)	cortical volumetric bone mineral density (CMO:0001730)	4	135699135	180699135	Rat
2293659	Bmd35	Bone mineral density QTL 35	4.5	0.0001	femur strength trait (VT:0010010)	femoral neck ultimate force (CMO:0001703)	4	137755016	181392681	Rat
61362	Oia2	Oil induced arthritis QTL 2		0.001	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	138503169	173369699	Rat
1298524	Oia8	Oil induced arthritis QTL 8			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	138503169	173369699	Rat
1331738	Bp209	Blood pressure QTL 209	2.979		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	4	138503169	179293946	Rat
6478718	Anxrr34	Anxiety related response QTL 34		0.00896	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	144639524	182687754	Rat
6478748	Anxrr42	Anxiety related response QTL 42		0.28008	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	144639524	182687754	Rat
6478754	Anxrr43	Anxiety related response QTL 43		0.14035	locomotor behavior trait (VT:0001392)	distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)	4	144639524	182687754	Rat
6478693	Anxrr32	Anxiety related response QTL 32		0.00092	locomotor behavior trait (VT:0001392)	measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)	4	144639524	182687754	Rat
6478700	Anxrr33	Anxiety related response QTL 33		0.00896	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	144639524	182687754	Rat
10401796	Kidm48	Kidney mass QTL 48			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	4	145568712	182687754	Rat
634342	Cia24	Collagen induced arthritis QTL 24	4.5		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	146565735	175236377	Rat
10053718	Scort25	Serum corticosterone level QTL 25	2.15	0.0097	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	4	155561574	182687754	Rat
1300109	Rf13	Renal function QTL 13	3.91		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	4	157710145	182687754	Rat

Markers in Region

D4Rat69

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	4	170,730,137 - 170,730,299 (+)	MAPPER	mRatBN7.2
Rnor_6.0	4	171,813,837 - 171,813,998	NCBI	Rnor6.0
Rnor_5.0	4	236,070,607 - 236,070,768	UniSTS	Rnor5.0
RGSC_v3.4	4	174,948,632 - 174,948,794	RGD	RGSC3.4
RGSC_v3.4	4	174,948,633 - 174,948,794	UniSTS	RGSC3.4
RGSC_v3.1	4	175,193,756 - 175,193,918	RGD
Celera	4	159,306,232 - 159,306,393	UniSTS
RH 2.0 Map	4	1062.7	RGD
SHRSP x BN Map	4	91.8399	RGD
FHH x ACI Map	4	111.33	RGD
Cytogenetic Map	4	q44	UniSTS

RH132144

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	4	170,675,423 - 170,675,605 (+)	MAPPER	mRatBN7.2
Rnor_6.0	4	171,760,008 - 171,760,189	NCBI	Rnor6.0
Rnor_5.0	4	236,016,880 - 236,017,061	UniSTS	Rnor5.0
RGSC_v3.4	4	174,892,883 - 174,893,064	UniSTS	RGSC3.4
Celera	4	159,251,644 - 159,251,825	UniSTS
RH 3.4 Map	4	1027.1	UniSTS
Cytogenetic Map	4	q44	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	35	57	41	19	41	5	8	66	35	34	11	5
Low		8					3	3	8		7		3
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001399006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_003749862	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_003753958	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473964	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ212862	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ219539	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000151	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000009998 ⟹ ENSRNOP00000009998

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	4	170,663,665 - 170,742,469 (+)	Ensembl
Rnor_6.0 Ensembl	4	171,748,273 - 171,826,409 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000114322 ⟹ ENSRNOP00000092261

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	4	170,663,763 - 170,742,470 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000116905 ⟹ ENSRNOP00000088760

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	4	170,663,665 - 170,758,865 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000117802 ⟹ ENSRNOP00000087892

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	4	170,685,252 - 170,742,470 (+)	Ensembl

RefSeq Acc Id:

XM_003749862 ⟹ XP_003749910

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	4	170,663,646 - 170,742,469 (+)	NCBI
Rnor_6.0	4	171,748,254 - 171,826,414 (+)	NCBI
Rnor_5.0	4	236,005,130 - 236,082,656 (+)	NCBI

Sequence:

show sequence

CGTGGCTCAGGGCGGGCATTTGGCAGGAAGGAGGAAGACCAGGCCTGTGTGGCGCCCTACCCTG
GTGCAAGAGTTACCTTTCAGCTGTGGCCGCAATGGCTGCTCACTGCCGGGGCACAGAGCTCGAT
CTCAGCTGGGTCTCCAGAGTTCAAGTGAACCATGCGGCTGTGCTGAGGCGGGCCGAGCAGATCC
AGGCCCGCCGAAGTGTGAAGAAGGAATGGCAGGCTGCGTGGCTCCTGAAAGCTGTCACGTTCAT
AGACCTCACCACGCTTTCTGGTGATGACACGTTTTCCAACGTTCAACGGCTCTGTTATAAAGCC
AAATATCCAATCCGGGCAGACCTCTTAAAAGCCTTAAATATGCATGACGAAGGTATCACCACGG
CTGCGGTCTGTGTTTACCCTGCCCGGGTCTGCGATGCTGTGAAGGCACTGAAGGCCGCAGGCTG
CAGGATCCCTGTGGCATCAGTGGCCACTGGCTTTCCAGCTGGACAGACTCATTTAAAGACTCGA
TTGGAAGAGGTCAGACTGGCAGTGGAGGACGGAGCTACTGAAATCGACGTGGTCATTAACAGGA
CCTTGGTGCTGACTGGCCAGTGGGAAGCTCTCTACGATGAGATCACTCAGTTTCGAAAGGCCTG
TGGGGAGGCCCATCTCAAAACCATCTTGGCTACGGGAGAGCTCGGCTCTCTCACCAACATCTAC
AAAGCCAGCCTGGTAGCAATGATGGCGGGATCAGATTTTATTAAGACCTCTACTGGAAAAGAAA
CAGTAAACGCCACCTTCCCGGTAGCCATCGTGATGCTGCGGGCCATTAGAGATTTCTTCTGGAA
AACTGGAAACAAGGTAGGCTTTAAGCCTGCAGGAGGCATCCGTACAGCGAAGGAATCCCTTGTG
TGGCTCTCTCTGGTAAAGGAGGAACTGGGGGATGAGTGGCTGACTCCCGACCTCTTCCGGATAG
GGGCCAGCTCTCTGCTCTCCGACATCGAGAGACAGATTTACCATCACGTGACTGGACGATATGC
GGCTTATCACGATCTTCCAATGTCTTAGGTCAGCAGCCAGCCCAGAAAAGCATCTTGCAACAAA
TTTTTTTTTAAAAAATGTTTTTGCATAATTGCTAAGGTTATGTAATTACAGAGCCATTAACTGA
CTCCCCCCCCACTAAAATCCCCCCTGAAATCAACTCAGAACAATAGAGGAAACAAACCAGTCGA
ATCTAAATGTGGAACTCAAATCAAGAAAGGTTGAAATGGTCTTCATTACCAAGATGTCTGCATT
TATTAATTTTGTGAAGATTTTCTCTGAAAAACTCAGGAAAAAATGTTTCTACTAACCCGTACTG
CAGAAAATTCTGAAGGGAAAATGGAGTTAAATTGCCTGAGACCTGAGATTCCAGGGCAGGCGGG
GCCTGGAGGGAAGGGTGCTTGTTACCAGACCTGACACCCTGTTCCGCTCTCAGTAACTACAGGG
TGGACGGGGAGAACGGACACCAAAGATTGTCCTCGATGATCACATAGCCATGTCCCCTATCTCT
GACGCATAATAAATAAATTAAAAATGGGATCAAAATTAAAATGGGTGCTACAGCAAAGGGACAC
TCTGCCTCCCTGTGCTGCCTCCCATTGGAGCCCTGCCCTGGCATCCACCTGACCTTCTGTGCTG
TACAGAACACTCTCATTAATTGTTTGCTAACGAGATTATGATGTTGTTGCAAGAAAATGTGAAT
AACACTGAATTTTAAATACAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001385935	(Get FASTA)	NCBI Sequence Viewer
	XP_003749910	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM01579	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

XP_003749910 ⟸ XM_003749862

- UniProtKB:

F1M1H0 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAAHCRGTELDLSWVSRVQVNHAAVLRRAEQIQARRSVKKEWQAAWLLKAVTFIDLTTLSGDDT
FSNVQRLCYKAKYPIRADLLKALNMHDEGITTAAVCVYPARVCDAVKALKAAGCRIPVASVATG
FPAGQTHLKTRLEEVRLAVEDGATEIDVVINRTLVLTGQWEALYDEITQFRKACGEAHLKTILA
TGELGSLTNIYKASLVAMMAGSDFIKTSTGKETVNATFPVAIVMLRAIRDFFWKTGNKVGFKPA
GGIRTAKESLVWLSLVKEELGDEWLTPDLFRIGASSLLSDIERQIYHHVTGRYAAYHDLPMS

hide sequence

RefSeq Acc Id:

ENSRNOP00000009998 ⟸ ENSRNOT00000009998

RefSeq Acc Id:

ENSRNOP00000088760 ⟸ ENSRNOT00000116905

RefSeq Acc Id:

ENSRNOP00000087892 ⟸ ENSRNOT00000117802

RefSeq Acc Id:

ENSRNOP00000092261 ⟸ ENSRNOT00000114322

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F1M1H0-F1-model_v2	AlphaFold	F1M1H0	1-318	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13693473

Promoter ID:

EPDNEW_R3996

Type:

initiation region

Name:

Dera_1

Description:

deoxyribose-phosphate aldolase

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	4	171,748,298 - 171,748,358	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1589836	AgrOrtholog
BioCyc Gene	G2FUF-42568	BioCyc
Ensembl Genes	ENSRNOG00000007570	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000009998	ENTREZGENE
	ENSRNOP00000009998.5	UniProtKB/TrEMBL
	ENSRNOP00000087892.1	UniProtKB/TrEMBL
	ENSRNOP00000088760.1	UniProtKB/TrEMBL
	ENSRNOP00000092261.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000009998	ENTREZGENE
	ENSRNOT00000009998.5	UniProtKB/TrEMBL
	ENSRNOT00000114322.1	UniProtKB/TrEMBL
	ENSRNOT00000116905.1	UniProtKB/TrEMBL
	ENSRNOT00000117802.1	UniProtKB/TrEMBL
Gene3D-CATH	3.20.20.70	UniProtKB/TrEMBL
InterPro	Aldolase_TIM	UniProtKB/TrEMBL
	DeoC	UniProtKB/TrEMBL
	DeoC/FbaB/lacD_aldolase	UniProtKB/TrEMBL
KEGG Report	rno:690945	UniProtKB/TrEMBL
NCBI Gene	690945	ENTREZGENE
PANTHER	PTHR10889	UniProtKB/TrEMBL
Pfam	DeoC	UniProtKB/TrEMBL
PhenoGen	Dera	PhenoGen
PIRSF	DeoC	UniProtKB/TrEMBL
SMART	DeoC	UniProtKB/TrEMBL
TIGRFAMs	deoC	UniProtKB/TrEMBL
UniProt	A0A8I6A8V2_RAT	UniProtKB/TrEMBL
	A0A8I6AAD4_RAT	UniProtKB/TrEMBL
	A0A8I6AHH8_RAT	UniProtKB/TrEMBL
	F1M1H0	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-03-15	Dera	deoxyribose-phosphate aldolase	Dera	deoxyribose-phosphate aldolase (putative)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2012-07-16	Dera	deoxyribose-phosphate aldolase (putative)	Dera-ps1	deoxyribose-phosphate aldolase, pseudogene 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2012-06-26	Dera-ps1	deoxyribose-phosphate aldolase, pseudogene 1	Dera-ps1	2-deoxyribose-5-phosphate aldolase homolog (C. elegans), pseudogene 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2011-06-08	Dera-ps1	2-deoxyribose-5-phosphate aldolase homolog (C. elegans), pseudogene 1	Dera	2-deoxyribose-5-phosphate aldolase homolog (C. elegans)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-11-21	Dera	2-deoxyribose-5-phosphate aldolase homolog (C. elegans)	LOC690945	similar to Putative deoxyribose-phosphate aldolase (Phosphodeoxyriboaldolase) (Deoxyriboaldolase) (DERA)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-01-09	LOC690945	similar to Putative deoxyribose-phosphate aldolase (Phosphodeoxyriboaldolase) (Deoxyriboaldolase) (DERA)	LOC686184	similar to Putative deoxyribose-phosphate aldolase (Phosphodeoxyriboaldolase) (Deoxyriboaldolase) (DERA)	Data Merged	1643240	APPROVED
2006-11-20	LOC690945	similar to Putative deoxyribose-phosphate aldolase (Phosphodeoxyriboaldolase) (Deoxyriboaldolase) (DERA)			Symbol and Name status set to provisional	70820	PROVISIONAL
2006-11-19	LOC686184	similar to Putative deoxyribose-phosphate aldolase (Phosphodeoxyriboaldolase) (Deoxyriboaldolase) (DERA)			Symbol and Name status set to provisional	70820	PROVISIONAL

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Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

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Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

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MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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