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Gene: Prkcd (protein kinase C, delta) Rattus norvegicus
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Symbol: Prkcd
Name: protein kinase C, delta
Description: Exhibits TIR domain binding activity; calcium-independent protein kinase C activity; and protein kinase binding activity. Involved in several processes, including D-aspartate import across plasma membrane; aging; and positive regulation of glucose import. Localizes to the cytoplasm; nucleus; and plasma membrane. Used to study brain ischemia and hypertension. Biomarker of hyperinsulinism; hypertension; muscular disease; obesity; and restrictive cardiomyopathy. Human ortholog(s) of this gene implicated in autoimmune lymphoproliferative syndrome type 3 and fatty liver disease. Orthologous to human PRKCD (protein kinase C delta); PARTICIPATES IN the extracellular signal-regulated Raf/Mek/Erk signaling pathway; vascular endothelial growth factor signaling pathway; ceramide signaling pathway; INTERACTS WITH (+)-pilocarpine; (R)-mevalonic acid; (RS)-amphetamine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: nPKC-delta; Pkcd; protein kinase C delta type
Orthologs:
Homo sapiens (human) : PRKCD (protein kinase C delta)  HGNC  Alliance
Mus musculus (house mouse) : Prkcd (protein kinase C, delta)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prkcd (protein kinase C delta)
Pan paniscus (bonobo/pygmy chimpanzee) : PRKCD (protein kinase C delta)
Canis lupus familiaris (dog) : PRKCD (protein kinase C delta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prkcd (protein kinase C delta)
Sus scrofa (pig) : PRKCD (protein kinase C delta)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0166,655,131 - 6,675,746 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0166,588,990 - 6,608,725 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4165,954,218 - 5,975,743 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1165,954,214 - 5,975,741 (-)NCBI
Celera169,398,816 - 9,419,806 (+)NCBICelera
Cytogenetic Map16p16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Prkcd
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 67383
Created: 2001-06-01
Species: Rattus norvegicus
Last Modified: 2019-09-03
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.