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Gene: Mvp (major vault protein) Rattus norvegicus
Symbol: Mvp
Name: major vault protein
Description: Predicted to have identical protein binding activity; protein kinase binding activity; and protein phosphatase binding activity. Predicted to be involved in several processes, including negative regulation of epidermal growth factor receptor signaling pathway; negative regulation of protein phosphorylation; and protein activation cascade. Predicted to localize to several cellular components, including cytoskeleton; cytosol; and perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in mitral valve prolapse. Orthologous to human MVP (major vault protein); INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Homo sapiens (human) : MVP (major vault protein)  HGNC  Alliance
Mus musculus (house mouse) : Mvp (major vault protein)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mvp (major vault protein)
Pan paniscus (bonobo/pygmy chimpanzee) : MVP (major vault protein)
Canis lupus familiaris (dog) : MVP (major vault protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mvp (major vault protein)
Sus scrofa (pig) : MVP (major vault protein)
Chlorocebus sabaeus (African green monkey) : MVP (major vault protein)
Heterocephalus glaber (naked mole-rat) : Mvp (major vault protein)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01198,420,813 - 198,448,612 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1198,420,806 - 198,450,047 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01205,401,190 - 205,428,854 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41186,164,811 - 186,192,802 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11186,314,691 - 186,342,683 (-)NCBI
Celera1179,249,451 - 179,276,973 (-)NCBICelera
Cytogenetic Map1q37NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Mvp
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 70932
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.